-
1
-
-
34248202517
-
Tying the loose ends together in DNA double strand break repair with 53BP1
-
Adams M.M., Carpenter P.B. Tying the loose ends together in DNA double strand break repair with 53BP1. Cell Div. 2006, 1:19.
-
(2006)
Cell Div.
, vol.1
, pp. 19
-
-
Adams, M.M.1
Carpenter, P.B.2
-
2
-
-
0035134286
-
Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage
-
Anderson L., Henderson C., Adachi Y. Phosphorylation and rapid relocalization of 53BP1 to nuclear foci upon DNA damage. Mol. Cell. Biol. 2001, 21:1719-1729.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 1719-1729
-
-
Anderson, L.1
Henderson, C.2
Adachi, Y.3
-
3
-
-
33646117239
-
Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks
-
Bekker-Jensen S., Lukas C., Kitagawa R., Melander F., Kastan M.B., Bartek J., Lukas J. Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks. J. Cell Biol. 2006, 173:195-206.
-
(2006)
J. Cell Biol.
, vol.173
, pp. 195-206
-
-
Bekker-Jensen, S.1
Lukas, C.2
Kitagawa, R.3
Melander, F.4
Kastan, M.B.5
Bartek, J.6
Lukas, J.7
-
4
-
-
77649267656
-
Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70
-
Boboila C., Jankovic M., Yan C.T., Wang J.H., Wesemann D.R., Zhang T., Fazeli A., Feldman L., Nussenzweig A., Nussenzweig M., Alt F.W. Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70. Proc. Natl. Acad. Sci. USA 2010, 107:3034-3039.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 3034-3039
-
-
Boboila, C.1
Jankovic, M.2
Yan, C.T.3
Wang, J.H.4
Wesemann, D.R.5
Zhang, T.6
Fazeli, A.7
Feldman, L.8
Nussenzweig, A.9
Nussenzweig, M.10
Alt, F.W.11
-
5
-
-
77149176004
-
Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4
-
Boboila C., Yan C., Wesemann D.R., Jankovic M., Wang J.H., Manis J., Nussenzweig A., Nussenzweig M., Alt F.W. Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4. J. Exp. Med. 2010, 207:417-427.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 417-427
-
-
Boboila, C.1
Yan, C.2
Wesemann, D.R.3
Jankovic, M.4
Wang, J.H.5
Manis, J.6
Nussenzweig, A.7
Nussenzweig, M.8
Alt, F.W.9
-
6
-
-
29244456155
-
The GAR motif of 53BP1 is arginine methylated by PRMT1 and is necessary for 53BP1 DNA binding activity
-
Boisvert F.M., Rhie A., Richard S., Doherty A.J. The GAR motif of 53BP1 is arginine methylated by PRMT1 and is necessary for 53BP1 DNA binding activity. Cell Cycle 2005, 4:1834-1841.
-
(2005)
Cell Cycle
, vol.4
, pp. 1834-1841
-
-
Boisvert, F.M.1
Rhie, A.2
Richard, S.3
Doherty, A.J.4
-
7
-
-
77951057068
-
53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination
-
Bothmer A., Robbiani D.F., Feldhahn N., Gazumyan A., Nussenzweig A., Nussenzweig M.C. 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination. J. Exp. Med. 2010, 207:855-865.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 855-865
-
-
Bothmer, A.1
Robbiani, D.F.2
Feldhahn, N.3
Gazumyan, A.4
Nussenzweig, A.5
Nussenzweig, M.C.6
-
8
-
-
33845666681
-
Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair
-
Botuyan M.V., Lee J., Ward I.M., Kim J.E., Thompson J.R., Chen J., Mer G. Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair. Cell 2006, 127:1361-1373.
-
(2006)
Cell
, vol.127
, pp. 1361-1373
-
-
Botuyan, M.V.1
Lee, J.2
Ward, I.M.3
Kim, J.E.4
Thompson, J.R.5
Chen, J.6
Mer, G.7
-
9
-
-
77950958141
-
53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks
-
Bunting S.F., Callén E., Wong N., Chen H.T., Polato F., Gunn A., Bothmer A., Feldhahn N., Fernandez-Capetillo O., Cao L., et al. 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks. Cell 2010, 141:243-254.
-
(2010)
Cell
, vol.141
, pp. 243-254
-
-
Bunting, S.F.1
Callén, E.2
Wong, N.3
Chen, H.T.4
Polato, F.5
Gunn, A.6
Bothmer, A.7
Feldhahn, N.8
Fernandez-Capetillo, O.9
Cao, L.10
-
10
-
-
0037012845
-
Genomic instability in mice lacking histone H2AX
-
Celeste A., Petersen S., Romanienko P.J., Fernandez-Capetillo O., Chen H.T., Sedelnikova O.A., Reina-San-Martin B., Coppola V., Meffre E., Difilippantonio M.J., et al. Genomic instability in mice lacking histone H2AX. Science 2002, 296:922-927.
-
(2002)
Science
, vol.296
, pp. 922-927
-
-
Celeste, A.1
Petersen, S.2
Romanienko, P.J.3
Fernandez-Capetillo, O.4
Chen, H.T.5
Sedelnikova, O.A.6
Reina-San-Martin, B.7
Coppola, V.8
Meffre, E.9
Difilippantonio, M.J.10
-
11
-
-
0037711771
-
Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks
-
Celeste A., Fernandez-Capetillo O., Kruhlak M.J., Pilch D.R., Staudt D.W., Lee A., Bonner R.F., Bonner W.M., Nussenzweig A. Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks. Nat. Cell Biol. 2003, 5:675-679.
-
(2003)
Nat. Cell Biol.
, vol.5
, pp. 675-679
-
-
Celeste, A.1
Fernandez-Capetillo, O.2
Kruhlak, M.J.3
Pilch, D.R.4
Staudt, D.W.5
Lee, A.6
Bonner, R.F.7
Bonner, W.M.8
Nussenzweig, A.9
-
12
-
-
57049124828
-
53BP1 facilitates long-range DNA end-joining during V(D)J recombination
-
Difilippantonio S., Gapud E., Wong N., Huang C.Y., Mahowald G., Chen H.T., Kruhlak M.J., Callen E., Livak F., Nussenzweig M.C., et al. 53BP1 facilitates long-range DNA end-joining during V(D)J recombination. Nature 2008, 456:529-533.
-
(2008)
Nature
, vol.456
, pp. 529-533
-
-
Difilippantonio, S.1
Gapud, E.2
Wong, N.3
Huang, C.Y.4
Mahowald, G.5
Chen, H.T.6
Kruhlak, M.J.7
Callen, E.8
Livak, F.9
Nussenzweig, M.C.10
-
13
-
-
57049132043
-
53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility
-
Dimitrova N., Chen Y.C., Spector D.L., de Lange T. 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility. Nature 2008, 456:524-528.
-
(2008)
Nature
, vol.456
, pp. 524-528
-
-
Dimitrova, N.1
Chen, Y.C.2
Spector, D.L.3
de Lange, T.4
-
14
-
-
0036902410
-
53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer
-
DiTullio R.A., Mochan T.A., Venere M., Bartkova J., Sehested M., Bartek J., Halazonetis T.D. 53BP1 functions in an ATM-dependent checkpoint pathway that is constitutively activated in human cancer. Nat. Cell Biol. 2002, 4:998-1002.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 998-1002
-
-
DiTullio, R.A.1
Mochan, T.A.2
Venere, M.3
Bartkova, J.4
Sehested, M.5
Bartek, J.6
Halazonetis, T.D.7
-
15
-
-
59049091728
-
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
-
Doil C., Mailand N., Bekker-Jensen S., Menard P., Larsen D.H., Pepperkok R., Ellenberg J., Panier S., Durocher D., Bartek J., et al. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins. Cell 2009, 136:435-446.
-
(2009)
Cell
, vol.136
, pp. 435-446
-
-
Doil, C.1
Mailand, N.2
Bekker-Jensen, S.3
Menard, P.4
Larsen, D.H.5
Pepperkok, R.6
Ellenberg, J.7
Panier, S.8
Durocher, D.9
Bartek, J.10
-
16
-
-
0036903037
-
DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1
-
Fernandez-Capetillo O., Chen H.T., Celeste A., Ward I., Romanienko P.J., Morales J.C., Naka K., Xia Z., Camerini-Otero R.D., Motoyama N., et al. DNA damage-induced G2-M checkpoint activation by histone H2AX and 53BP1. Nat. Cell Biol. 2002, 4:993-997.
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 993-997
-
-
Fernandez-Capetillo, O.1
Chen, H.T.2
Celeste, A.3
Ward, I.4
Romanienko, P.J.5
Morales, J.C.6
Naka, K.7
Xia, Z.8
Camerini-Otero, R.D.9
Motoyama, N.10
-
17
-
-
1542515338
-
A census of human cancer genes
-
Futreal P.A., Coin L., Marshall M., Down T., Hubbard T., Wooster R., Rahman N., Stratton M.R. A census of human cancer genes. Nat. Rev. Cancer 2004, 4:177-183.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 177-183
-
-
Futreal, P.A.1
Coin, L.2
Marshall, M.3
Down, T.4
Hubbard, T.5
Wooster, R.6
Rahman, N.7
Stratton, M.R.8
-
18
-
-
0030886293
-
Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse
-
Guo F., Gopaul D.N., van Duyne G.D. Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse. Nature 1997, 389:40-46.
-
(1997)
Nature
, vol.389
, pp. 40-46
-
-
Guo, F.1
Gopaul, D.N.2
van Duyne, G.D.3
-
19
-
-
78651406669
-
H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes
-
Helmink B.A., Tubbs A.T., Dorsett Y., Bednarski J.J., Walker L.M., Feng Z., Sharma G.G., McKinnon P.J., Zhang J., Bassing C.H., Sleckman B.P. H2AX prevents CtIP-mediated DNA end resection and aberrant repair in G1-phase lymphocytes. Nature 2011, 469:245-249.
-
(2011)
Nature
, vol.469
, pp. 245-249
-
-
Helmink, B.A.1
Tubbs, A.T.2
Dorsett, Y.3
Bednarski, J.J.4
Walker, L.M.5
Feng, Z.6
Sharma, G.G.7
McKinnon, P.J.8
Zhang, J.9
Bassing, C.H.10
Sleckman, B.P.11
-
20
-
-
70349859881
-
DNA damage, aging, and cancer
-
Hoeijmakers J.H. DNA damage, aging, and cancer. N. Engl. J. Med. 2009, 361:1475-1485.
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 1475-1485
-
-
Hoeijmakers, J.H.1
-
21
-
-
36249031962
-
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly
-
Huen M.S., Grant R., Manke I., Minn K., Yu X., Yaffe M.B., Chen J. RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly. Cell 2007, 131:901-914.
-
(2007)
Cell
, vol.131
, pp. 901-914
-
-
Huen, M.S.1
Grant, R.2
Manke, I.3
Minn, K.4
Yu, X.5
Yaffe, M.B.6
Chen, J.7
-
22
-
-
77949708459
-
Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1
-
Huen M.S., Huang J., Leung J.W., Sy S.M., Leung K.M., Ching Y.P., Tsao S.W., Chen J. Regulation of chromatin architecture by the PWWP domain-containing DNA damage-responsive factor EXPAND1/MUM1. Mol. Cell 2010, 37:854-864.
-
(2010)
Mol. Cell
, vol.37
, pp. 854-864
-
-
Huen, M.S.1
Huang, J.2
Leung, J.W.3
Sy, S.M.4
Leung, K.M.5
Ching, Y.P.6
Tsao, S.W.7
Chen, J.8
-
23
-
-
9244252580
-
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
-
Huyen Y., Zgheib O., Ditullio R.A., Gorgoulis V.G., Zacharatos P., Petty T.J., Sheston E.A., Mellert H.S., Stavridi E.S., Halazonetis T.D. Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks. Nature 2004, 432:406-411.
-
(2004)
Nature
, vol.432
, pp. 406-411
-
-
Huyen, Y.1
Zgheib, O.2
Ditullio, R.A.3
Gorgoulis, V.G.4
Zacharatos, P.5
Petty, T.J.6
Sheston, E.A.7
Mellert, H.S.8
Stavridi, E.S.9
Halazonetis, T.D.10
-
24
-
-
0141815630
-
Potential role for 53BP1 in DNA end-joining repair through direct interaction with DNA
-
Iwabuchi K., Basu B.P., Kysela B., Kurihara T., Shibata M., Guan D., Cao Y., Hamada T., Imamura K., Jeggo P.A., et al. Potential role for 53BP1 in DNA end-joining repair through direct interaction with DNA. J. Biol. Chem. 2003, 278:36487-36495.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 36487-36495
-
-
Iwabuchi, K.1
Basu, B.P.2
Kysela, B.3
Kurihara, T.4
Shibata, M.5
Guan, D.6
Cao, Y.7
Hamada, T.8
Imamura, K.9
Jeggo, P.A.10
-
25
-
-
77955841149
-
Collaboration and competition between DNA double-strand break repair pathways
-
Kass E.M., Jasin M. Collaboration and competition between DNA double-strand break repair pathways. FEBS Lett. 2010, 584:3703-3708.
-
(2010)
FEBS Lett.
, vol.584
, pp. 3703-3708
-
-
Kass, E.M.1
Jasin, M.2
-
26
-
-
36749084931
-
Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase
-
Kolas N.K., Chapman J.R., Nakada S., Ylanko J., Chahwan R., Sweeney F.D., Panier S., Mendez M., Wildenhain J., Thomson T.M., et al. Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase. Science 2007, 318:1637-1640.
-
(2007)
Science
, vol.318
, pp. 1637-1640
-
-
Kolas, N.K.1
Chapman, J.R.2
Nakada, S.3
Ylanko, J.4
Chahwan, R.5
Sweeney, F.D.6
Panier, S.7
Mendez, M.8
Wildenhain, J.9
Thomson, T.M.10
-
27
-
-
57049114872
-
S1219 residue of 53BP1 is phosphorylated by ATM kinase upon DNA damage and required for proper execution of DNA damage response
-
Lee H., Kwak H.J., Cho I.T., Park S.H., Lee C.H. S1219 residue of 53BP1 is phosphorylated by ATM kinase upon DNA damage and required for proper execution of DNA damage response. Biochem. Biophys. Res. Commun. 2009, 378:32-36.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.378
, pp. 32-36
-
-
Lee, H.1
Kwak, H.J.2
Cho, I.T.3
Park, S.H.4
Lee, C.H.5
-
28
-
-
77953229115
-
The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway
-
Lieber M.R. The mechanism of double-strand DNA break repair by the nonhomologous DNA end-joining pathway. Annu. Rev. Biochem. 2010, 79:181-211.
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 181-211
-
-
Lieber, M.R.1
-
29
-
-
36248966246
-
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
-
Mailand N., Bekker-Jensen S., Faustrup H., Melander F., Bartek J., Lukas C., Lukas J. RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins. Cell 2007, 131:887-900.
-
(2007)
Cell
, vol.131
, pp. 887-900
-
-
Mailand, N.1
Bekker-Jensen, S.2
Faustrup, H.3
Melander, F.4
Bartek, J.5
Lukas, C.6
Lukas, J.7
-
30
-
-
2442707746
-
53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination
-
Manis J.P., Morales J.C., Xia Z., Kutok J.L., Alt F.W., Carpenter P.B. 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination. Nat. Immunol. 2004, 5:481-487.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 481-487
-
-
Manis, J.P.1
Morales, J.C.2
Xia, Z.3
Kutok, J.L.4
Alt, F.W.5
Carpenter, P.B.6
-
31
-
-
0037772381
-
Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability
-
Morales J.C., Xia Z., Lu T., Aldrich M.B., Wang B., Rosales C., Kellems R.E., Hittelman W.N., Elledge S.J., Carpenter P.B. Role for the BRCA1 C-terminal repeats (BRCT) protein 53BP1 in maintaining genomic stability. J. Biol. Chem. 2003, 278:14971-14977.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 14971-14977
-
-
Morales, J.C.1
Xia, Z.2
Lu, T.3
Aldrich, M.B.4
Wang, B.5
Rosales, C.6
Kellems, R.E.7
Hittelman, W.N.8
Elledge, S.J.9
Carpenter, P.B.10
-
32
-
-
0034268780
-
Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme
-
Muramatsu M., Kinoshita K., Fagarasan S., Yamada S., Shinkai Y., Honjo T. Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme. Cell 2000, 102:553-563.
-
(2000)
Cell
, vol.102
, pp. 553-563
-
-
Muramatsu, M.1
Kinoshita, K.2
Fagarasan, S.3
Yamada, S.4
Shinkai, Y.5
Honjo, T.6
-
33
-
-
77950955761
-
Origin of chromosomal translocations in lymphoid cancer
-
Nussenzweig A., Nussenzweig M.C. Origin of chromosomal translocations in lymphoid cancer. Cell 2010, 141:27-38.
-
(2010)
Cell
, vol.141
, pp. 27-38
-
-
Nussenzweig, A.1
Nussenzweig, M.C.2
-
34
-
-
33644643189
-
Role of genomic instability and p53 in AID-induced c-myc-Igh translocations
-
Ramiro A.R., Jankovic M., Callen E., Difilippantonio S., Chen H.T., McBride K.M., Eisenreich T.R., Chen J., Dickins R.A., Lowe S.W., et al. Role of genomic instability and p53 in AID-induced c-myc-Igh translocations. Nature 2006, 440:105-109.
-
(2006)
Nature
, vol.440
, pp. 105-109
-
-
Ramiro, A.R.1
Jankovic, M.2
Callen, E.3
Difilippantonio, S.4
Chen, H.T.5
McBride, K.M.6
Eisenreich, T.R.7
Chen, J.8
Dickins, R.A.9
Lowe, S.W.10
-
35
-
-
0035972194
-
Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways
-
Rappold I., Iwabuchi K., Date T., Chen J. Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways. J. Cell Biol. 2001, 153:613-620.
-
(2001)
J. Cell Biol.
, vol.153
, pp. 613-620
-
-
Rappold, I.1
Iwabuchi, K.2
Date, T.3
Chen, J.4
-
36
-
-
0037866984
-
H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation
-
Reina-San-Martin B., Difilippantonio S., Hanitsch L., Masilamani R.F., Nussenzweig A., Nussenzweig M.C. H2AX is required for recombination between immunoglobulin switch regions but not for intra-switch region recombination or somatic hypermutation. J. Exp. Med. 2003, 197:1767-1778.
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1767-1778
-
-
Reina-San-Martin, B.1
Difilippantonio, S.2
Hanitsch, L.3
Masilamani, R.F.4
Nussenzweig, A.5
Nussenzweig, M.C.6
-
37
-
-
33846340098
-
Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells
-
Reina-San-Martin B., Chen J., Nussenzweig A., Nussenzweig M.C. Enhanced intra-switch region recombination during immunoglobulin class switch recombination in 53BP1-/- B cells. Eur. J. Immunol. 2007, 37:235-239.
-
(2007)
Eur. J. Immunol.
, vol.37
, pp. 235-239
-
-
Reina-San-Martin, B.1
Chen, J.2
Nussenzweig, A.3
Nussenzweig, M.C.4
-
38
-
-
0030818183
-
B lymphocyte-specific, Cre-mediated mutagenesis in mice
-
Rickert R.C., Roes J., Rajewsky K. B lymphocyte-specific, Cre-mediated mutagenesis in mice. Nucleic Acids Res. 1997, 25:1317-1318.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 1317-1318
-
-
Rickert, R.C.1
Roes, J.2
Rajewsky, K.3
-
39
-
-
57149146036
-
AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations
-
Robbiani D.F., Bothmer A., Callen E., Reina-San-Martin B., Dorsett Y., Difilippantonio S., Bolland D.J., Chen H.T., Corcoran A.E., Nussenzweig A., Nussenzweig M.C. AID is required for the chromosomal breaks in c-myc that lead to c-myc/IgH translocations. Cell 2008, 135:1028-1038.
-
(2008)
Cell
, vol.135
, pp. 1028-1038
-
-
Robbiani, D.F.1
Bothmer, A.2
Callen, E.3
Reina-San-Martin, B.4
Dorsett, Y.5
Difilippantonio, S.6
Bolland, D.J.7
Chen, H.T.8
Corcoran, A.E.9
Nussenzweig, A.10
Nussenzweig, M.C.11
-
40
-
-
8844248619
-
Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage
-
Sanders S.L., Portoso M., Mata J., Bähler J., Allshire R.C., Kouzarides T. Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage. Cell 2004, 119:603-614.
-
(2004)
Cell
, vol.119
, pp. 603-614
-
-
Sanders, S.L.1
Portoso, M.2
Mata, J.3
Bähler, J.4
Allshire, R.C.5
Kouzarides, T.6
-
41
-
-
77952294873
-
Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8
-
Santos M.A., Huen M.S., Jankovic M., Chen H.T., López-Contreras A.J., Klein I.A., Wong N., Barbancho J.L., Fernandez-Capetillo O., Nussenzweig M.C., et al. Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8. J. Exp. Med. 2010, 207:973-981.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 973-981
-
-
Santos, M.A.1
Huen, M.S.2
Jankovic, M.3
Chen, H.T.4
López-Contreras, A.J.5
Klein, I.A.6
Wong, N.7
Barbancho, J.L.8
Fernandez-Capetillo, O.9
Nussenzweig, M.C.10
-
42
-
-
65549129613
-
Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin
-
Savic V., Yin B., Maas N.L., Bredemeyer A.L., Carpenter A.C., Helmink B.A., Yang-Iott K.S., Sleckman B.P., Bassing C.H. Formation of dynamic gamma-H2AX domains along broken DNA strands is distinctly regulated by ATM and MDC1 and dependent upon H2AX densities in chromatin. Mol. Cell 2009, 34:298-310.
-
(2009)
Mol. Cell
, vol.34
, pp. 298-310
-
-
Savic, V.1
Yin, B.2
Maas, N.L.3
Bredemeyer, A.L.4
Carpenter, A.C.5
Helmink, B.A.6
Yang-Iott, K.S.7
Sleckman, B.P.8
Bassing, C.H.9
-
43
-
-
0034739853
-
P53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks
-
Schultz L.B., Chehab N.H., Malikzay A., Halazonetis T.D. p53 binding protein 1 (53BP1) is an early participant in the cellular response to DNA double-strand breaks. J. Cell Biol. 2000, 151:1381-1390.
-
(2000)
J. Cell Biol.
, vol.151
, pp. 1381-1390
-
-
Schultz, L.B.1
Chehab, N.H.2
Malikzay, A.3
Halazonetis, T.D.4
-
45
-
-
59049103900
-
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage
-
Stewart G.S., Panier S., Townsend K., Al-Hakim A.K., Kolas N.K., Miller E.S., Nakada S., Ylanko J., Olivarius S., Mendez M., et al. The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage. Cell 2009, 136:420-434.
-
(2009)
Cell
, vol.136
, pp. 420-434
-
-
Stewart, G.S.1
Panier, S.2
Townsend, K.3
Al-Hakim, A.K.4
Kolas, N.K.5
Miller, E.S.6
Nakada, S.7
Ylanko, J.8
Olivarius, S.9
Mendez, M.10
-
46
-
-
0038143321
-
Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX
-
Ward I.M., Minn K., Jorda K.G., Chen J. Accumulation of checkpoint protein 53BP1 at DNA breaks involves its binding to phosphorylated histone H2AX. J. Biol. Chem. 2003, 278:19579-19582.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 19579-19582
-
-
Ward, I.M.1
Minn, K.2
Jorda, K.G.3
Chen, J.4
-
47
-
-
2542463148
-
53BP1 is required for class switch recombination
-
Ward I.M., Reina-San-Martin B., Olaru A., Minn K., Tamada K., Lau J.S., Cascalho M., Chen L., Nussenzweig A., Livak F., et al. 53BP1 is required for class switch recombination. J. Cell Biol. 2004, 165:459-464.
-
(2004)
J. Cell Biol.
, vol.165
, pp. 459-464
-
-
Ward, I.M.1
Reina-San-Martin, B.2
Olaru, A.3
Minn, K.4
Tamada, K.5
Lau, J.S.6
Cascalho, M.7
Chen, L.8
Nussenzweig, A.9
Livak, F.10
-
48
-
-
33846015507
-
The tandem BRCT domain of 53BP1 is not required for its repair function
-
Ward I., Kim J.E., Minn K., Chini C.C., Mer G., Chen J. The tandem BRCT domain of 53BP1 is not required for its repair function. J. Biol. Chem. 2006, 281:38472-38477.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 38472-38477
-
-
Ward, I.1
Kim, J.E.2
Minn, K.3
Chini, C.C.4
Mer, G.5
Chen, J.6
-
49
-
-
65549143757
-
RAD18 promotes DNA double-strand break repair during G1 phase through chromatin retention of 53BP1
-
Watanabe K., Iwabuchi K., Sun J., Tsuji Y., Tani T., Tokunaga K., Date T., Hashimoto M., Yamaizumi M., Tateishi S. RAD18 promotes DNA double-strand break repair during G1 phase through chromatin retention of 53BP1. Nucleic Acids Res. 2009, 37:2176-2193.
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 2176-2193
-
-
Watanabe, K.1
Iwabuchi, K.2
Sun, J.3
Tsuji, Y.4
Tani, T.5
Tokunaga, K.6
Date, T.7
Hashimoto, M.8
Yamaizumi, M.9
Tateishi, S.10
-
50
-
-
0032587877
-
Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation
-
Xu X., Wagner K.U., Larson D., Weaver Z., Li C., Ried T., Hennighausen L., Wynshaw-Boris A., Deng C.X. Conditional mutation of Brca1 in mammary epithelial cells results in blunted ductal morphogenesis and tumour formation. Nat. Genet. 1999, 22:37-43.
-
(1999)
Nat. Genet.
, vol.22
, pp. 37-43
-
-
Xu, X.1
Wagner, K.U.2
Larson, D.3
Weaver, Z.4
Li, C.5
Ried, T.6
Hennighausen, L.7
Wynshaw-Boris, A.8
Deng, C.X.9
-
51
-
-
0034946638
-
Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis
-
Xu X., Qiao W., Linke S.P., Cao L., Li W.M., Furth P.A., Harris C.C., Deng C.X. Genetic interactions between tumor suppressors Brca1 and p53 in apoptosis, cell cycle and tumorigenesis. Nat. Genet. 2001, 28:266-271.
-
(2001)
Nat. Genet.
, vol.28
, pp. 266-271
-
-
Xu, X.1
Qiao, W.2
Linke, S.P.3
Cao, L.4
Li, W.M.5
Furth, P.A.6
Harris, C.C.7
Deng, C.X.8
-
52
-
-
74049095565
-
MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX
-
Yuan J., Chen J. MRE11-RAD50-NBS1 complex dictates DNA repair independent of H2AX. J. Biol. Chem. 2010, 285:1097-1104.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 1097-1104
-
-
Yuan, J.1
Chen, J.2
-
53
-
-
59449094470
-
An oligomerized 53BP1 tudor domain suffices for recognition of DNA double-strand breaks
-
Zgheib O., Pataky K., Brugger J., Halazonetis T.D. An oligomerized 53BP1 tudor domain suffices for recognition of DNA double-strand breaks. Mol. Cell. Biol. 2009, 29:1050-1058.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 1050-1058
-
-
Zgheib, O.1
Pataky, K.2
Brugger, J.3
Halazonetis, T.D.4
-
54
-
-
78651386197
-
ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks
-
Zha S., Guo C., Boboila C., Oksenych V., Cheng H.L., Zhang Y., Wesemann D.R., Yuen G., Patel H., Goff P.H., et al. ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks. Nature 2011, 469:250-254.
-
(2011)
Nature
, vol.469
, pp. 250-254
-
-
Zha, S.1
Guo, C.2
Boboila, C.3
Oksenych, V.4
Cheng, H.L.5
Zhang, Y.6
Wesemann, D.R.7
Yuen, G.8
Patel, H.9
Goff, P.H.10
-
55
-
-
77955875047
-
The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers
-
Zhang Y., Gostissa M., Hildebrand D.G., Becker M.S., Boboila C., Chiarle R., Lewis S., Alt F.W. The role of mechanistic factors in promoting chromosomal translocations found in lymphoid and other cancers. Adv. Immunol. 2010, 106:93-133.
-
(2010)
Adv. Immunol.
, vol.106
, pp. 93-133
-
-
Zhang, Y.1
Gostissa, M.2
Hildebrand, D.G.3
Becker, M.S.4
Boboila, C.5
Chiarle, R.6
Lewis, S.7
Alt, F.W.8
|