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Volumn 4, Issue 4, 2012, Pages 727-732

Deregulation of RAD21 and RUNX1 expression in endometrial cancer

Author keywords

Endometrial cancer; Gene dosage; Gene expression; Molecular markers; RAD21; RUNX1

Indexed keywords

MESSENGER RNA; NUCLEIC ACID BINDING PROTEIN; PROTEIN RAD21; TRANSCRIPTION FACTOR RUNX1; UNCLASSIFIED DRUG;

EID: 84864701783     PISSN: 17921074     EISSN: 17921082     Source Type: Journal    
DOI: 10.3892/ol.2012.794     Document Type: Article
Times cited : (28)

References (43)
  • 1
    • 0003964363 scopus 로고    scopus 로고
    • American Cancer Society, Atlanta: American Cancer Society
    • American Cancer Society: Cancer Facts & Figures 2011. Atlanta: American Cancer Society, 2011.
    • (2011) Cancer Facts & Figures 2011
  • 2
    • 0030885925 scopus 로고    scopus 로고
    • Cohesins: Chromosomal proteins that prevent premature separation of sister chromatids
    • Michaelis C, Ciosk R and Nasmyth K: Cohesins: chromosomal proteins that prevent premature separation of sister chromatids. Cell 91: 35-45, 1997.
    • (1997) Cell , vol.91 , pp. 35-45
    • Michaelis, C.1    Ciosk, R.2    Nasmyth, K.3
  • 3
    • 0030886602 scopus 로고    scopus 로고
    • A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae
    • Guacci V, Koshland D and Strunnikov A: A direct link between sister chromatid cohesion and chromosome condensation revealed through the analysis of MCD1 in S. cerevisiae. Cell 91: 47-57, 1997.
    • (1997) Cell , vol.91 , pp. 47-57
    • Guacci, V.1    Koshland, D.2    Strunnikov, A.3
  • 4
    • 33746662847 scopus 로고    scopus 로고
    • Cohesin and DNA damage repair
    • Watrin E and Peters JM: Cohesin and DNA damage repair. Exp Cell Res 312: 2687-2693, 2006.
    • (2006) Exp Cell Res , vol.312 , pp. 2687-2693
    • Watrin, E.1    Peters, J.M.2
  • 5
    • 18044404949 scopus 로고    scopus 로고
    • Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells
    • Sonoda E, Matsusaka T, Morrison C, et al: Scc1/Rad21/Mcd1 is required for sister chromatid cohesion and kinetochore function in vertebrate cells. Dev Cell 1: 759-770, 2001.
    • (2001) Dev Cell , vol.1 , pp. 759-770
    • Sonoda, E.1    Matsusaka, T.2    Morrison, C.3
  • 6
    • 34547762839 scopus 로고    scopus 로고
    • Cohesin-dependent regulation of Runx genes
    • Horsfield JA, Anagnostou SH, Hu JK, et al: Cohesin-dependent regulation of Runx genes. Development 134: 2639-2649, 2007.
    • (2007) Development , vol.134 , pp. 2639-2649
    • Horsfield, J.A.1    Anagnostou, S.H.2    Hu, J.K.3
  • 7
    • 37549014536 scopus 로고    scopus 로고
    • Transcription alters chromosomal locations of cohesin in Saccharomyces cerevisiae
    • Bausch C, Noone S, Henry JM, et al: Transcription alters chromosomal locations of cohesin in Saccharomyces cerevisiae. Mol Cell Biol 27: 8522-8532, 2007.
    • (2007) Mol Cell Biol , vol.27 , pp. 8522-8532
    • Bausch, C.1    Noone, S.2    Henry, J.M.3
  • 8
    • 15944424637 scopus 로고    scopus 로고
    • Suppression of RAD21 gene expression decreases cell growth and enhances cytotoxicity of etoposide and bleomycin in human breast cancer cells
    • Atienza JM, Roth RB, Rosette C, et al: Suppression of RAD21 gene expression decreases cell growth and enhances cytotoxicity of etoposide and bleomycin in human breast cancer cells. Mol Cancer Ther 4: 361-368, 2005.
    • (2005) Mol Cancer Ther , vol.4 , pp. 361-368
    • Atienza, J.M.1    Roth, R.B.2    Rosette, C.3
  • 9
    • 84860389200 scopus 로고    scopus 로고
    • Enhanced RAD21 cohesin expression confers poor prognosis and resistance to chemotherapy in high grade luminal, basal and HER2 breast cancers
    • Xu H, Yan M, Patra J, et al: Enhanced RAD21 cohesin expression confers poor prognosis and resistance to chemotherapy in high grade luminal, basal and HER2 breast cancers. Breast Cancer Res 13: R9, 2011.
    • (2011) Breast Cancer Res , vol.13
    • Xu, H.1    Yan, M.2    Patra, J.3
  • 10
    • 2442683158 scopus 로고    scopus 로고
    • Expression of a novel human gene, human wings apart-like (hWAPL), is associated with cervical carcinogenesis and tumor progression
    • Oikawa K, Ohbayashi T, Kiyono T, et al: Expression of a novel human gene, human wings apart-like (hWAPL), is associated with cervical carcinogenesis and tumor progression. Cancer Res 64: 3545-3549, 2004.
    • (2004) Cancer Res , vol.64 , pp. 3545-3549
    • Oikawa, K.1    Ohbayashi, T.2    Kiyono, T.3
  • 11
    • 33645576066 scopus 로고    scopus 로고
    • Correlation of invasion and metastasis of cancer cells, and expression of the RAD21 gene in oral squamous cell carcinoma
    • Yamamoto G, Irie T, Aida T, Nagoshi Y, Tsuchiya R and Tachikawa T: Correlation of invasion and metastasis of cancer cells, and expression of the RAD21 gene in oral squamous cell carcinoma. Virchows Arch 448: 435-441, 2006.
    • (2006) Virchows Arch , vol.448 , pp. 435-441
    • Yamamoto, G.1    Irie, T.2    Aida, T.3    Nagoshi, Y.4    Tsuchiya, R.5    Tachikawa, T.6
  • 13
    • 35248864084 scopus 로고    scopus 로고
    • Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression
    • Ryu B, Kim DS, Deluca AM and Alani RM: Comprehensive expression profiling of tumor cell lines identifies molecular signatures of melanoma progression. PLoS One 2: e594, 2007.
    • (2007) PLoS One , vol.2
    • Ryu, B.1    Kim, D.S.2    Deluca, A.M.3    Alani, R.M.4
  • 14
    • 10844236511 scopus 로고    scopus 로고
    • A differential gene expression profile reveals overexpression of RUNX1/AML1 in invasive endometrioid carcinoma
    • Planagumà J, Díaz-Fuertes M, Gil-Moreno A, et al: A differential gene expression profile reveals overexpression of RUNX1/AML1 in invasive endometrioid carcinoma. Cancer Res 64: 8846-8853, 2004.
    • (2004) Cancer Res , vol.64 , pp. 8846-8853
    • Planagumà, J.1    Díaz-Fuertes, M.2    Gil-Moreno, A.3
  • 15
    • 77957865812 scopus 로고    scopus 로고
    • Rad21-cohesin haploinsufficiency impedes DNA repair and enhances gastrointestinal radiosensitivity in mice
    • Xu H, Balakrishnan K, Malaterre J, et al: Rad21-cohesin haploinsufficiency impedes DNA repair and enhances gastrointestinal radiosensitivity in mice. PLoS One 5: e12112, 2010.
    • (2010) PLoS One , vol.5
    • Xu, H.1    Balakrishnan, K.2    Malaterre, J.3
  • 16
    • 79952030327 scopus 로고    scopus 로고
    • Can corruption of chromosome cohesion create a conduit to cancer?
    • Xu H, Tomaszewski JM and McKay MJ: Can corruption of chromosome cohesion create a conduit to cancer? Nat Rev Cancer 11: 199-210, 2011.
    • (2011) Nat Rev Cancer , vol.11 , pp. 199-210
    • Xu, H.1    Tomaszewski, J.M.2    McKay, M.J.3
  • 17
    • 18344372018 scopus 로고    scopus 로고
    • The RUNX genes: Gain or loss of function in cancer
    • Blyth K, Cameron ER and Neil JC: The RUNX genes: gain or loss of function in cancer. Nat Rev Cancer 5: 376-387, 2005.
    • (2005) Nat Rev Cancer , vol.5 , pp. 376-387
    • Blyth, K.1    Cameron, E.R.2    Neil, J.C.3
  • 18
    • 3042694117 scopus 로고    scopus 로고
    • Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression
    • Rhodes DR, Yu J, Shanker K, et al: Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression. Proc Natl Acad Sci USA 101: 9309-9314, 2004.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 9309-9314
    • Rhodes, D.R.1    Yu, J.2    Shanker, K.3
  • 19
    • 18244409687 scopus 로고    scopus 로고
    • Gene expression profiling predicts clinical outcome of breast cancer
    • van't Veer LJ, Dai H, van de Vijver MJ, et al: Gene expression profiling predicts clinical outcome of breast cancer. Nature 415: 530-536, 2002.
    • (2002) Nature , vol.415 , pp. 530-536
    • van't Veer, L.J.1    Dai, H.2    van de Vijver, M.J.3
  • 20
    • 68449088127 scopus 로고    scopus 로고
    • Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura: The emerging gene portrait of the mesothelioma phenotype
    • Røe OD, Anderssen E, Helge E, et al: Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura: the emerging gene portrait of the mesothelioma phenotype. PLoS One 4: e6554, 2009.
    • (2009) PLoS One , vol.4
    • Røe, O.D.1    Anderssen, E.2    Helge, E.3
  • 21
    • 67449093469 scopus 로고    scopus 로고
    • An orthotopic endometrial cancer mouse model demonstrates a role for RUNX1 in distant metastasis
    • Doll A, Gonzalez M, Abal M, et al: An orthotopic endometrial cancer mouse model demonstrates a role for RUNX1 in distant metastasis. Int J Cancer 125: 257-263, 2009.
    • (2009) Int J Cancer , vol.125 , pp. 257-263
    • Doll, A.1    Gonzalez, M.2    Abal, M.3
  • 22
    • 77958006665 scopus 로고    scopus 로고
    • Downregulation of activated leukemic oncogenes AML1-ETO and RUNX1(K83N) expression with RNA-interference
    • (In Russian)
    • Spirin PV, Baskaran F, Orlova NN, et al: Downregulation of activated leukemic oncogenes AML1-ETO and RUNX1(K83N) expression with RNA-interference. Mol Biol (Mosk) 44: 876-888, 2010 (In Russian).
    • (2010) Mol Biol (Mosk) , vol.44 , pp. 876-888
    • Spirin, P.V.1    Baskaran, F.2    Orlova, N.N.3
  • 23
    • 80052895701 scopus 로고    scopus 로고
    • Neuroblastoma cell proliferation is sensitive to changes in levels of RUNX1 and RUNX3 protein
    • Inoue K and Ito Y: Neuroblastoma cell proliferation is sensitive to changes in levels of RUNX1 and RUNX3 protein. Gene 487: 151-155, 2011.
    • (2011) Gene , vol.487 , pp. 151-155
    • Inoue, K.1    Ito, Y.2
  • 25
    • 80055108192 scopus 로고    scopus 로고
    • RUNX1 and its understudied role in breast cancer
    • Janes KA: RUNX1 and its understudied role in breast cancer. Cell Cycle 10: 3461-3465, 2011.
    • (2011) Cell Cycle , vol.10 , pp. 3461-3465
    • Janes, K.A.1
  • 26
    • 77249119762 scopus 로고    scopus 로고
    • The landscape of somatic copy-number alteration across human cancers
    • Beroukhim R, Mermel CH, Porter D, et al: The landscape of somatic copy-number alteration across human cancers. Nature 463: 899-905, 2010.
    • (2010) Nature , vol.463 , pp. 899-905
    • Beroukhim, R.1    Mermel, C.H.2    Porter, D.3
  • 27
    • 64049094855 scopus 로고    scopus 로고
    • Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium
    • Pecorelli S: Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. Int J Gynaecol Obstet 105: 103-104, 2009.
    • (2009) Int J Gynaecol Obstet , vol.105 , pp. 103-104
    • Pecorelli, S.1
  • 28
    • 21344466560 scopus 로고    scopus 로고
    • Nadir CA125 concentration as a prognostic indicator in ovarian cancer
    • Baron AT and Maihle N: Nadir CA125 concentration as a prognostic indicator in ovarian cancer. Nat Clin Pract Oncol 2: 288-289, 2005.
    • (2005) Nat Clin Pract Oncol , vol.2 , pp. 288-289
    • Baron, A.T.1    Maihle, N.2
  • 29
    • 85066456886 scopus 로고    scopus 로고
    • Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies
    • Consultation WE: Appropriate body-mass index for Asian populations and its implications for policy and intervention strategies. Lancet 363: 157-163, 2004.
    • (2004) Lancet , vol.363 , pp. 157-163
    • Consultation, W.E.1
  • 30
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCH0034
    • Vandesompele J, De Preter K, Pattyn F, et al: Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 3: RESEARCH0034, 2002.
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    de Preter, K.2    Pattyn, F.3
  • 31
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW: A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: e45, 2001.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 32
    • 77953725585 scopus 로고    scopus 로고
    • Clinical evaluation of developed PCR-based method with hydrolysis probes for TOP2A copy number evaluation in breast cancer samples
    • Zaczek A, Markiewicz A, Jaskiewicz J, et al: Clinical evaluation of developed PCR-based method with hydrolysis probes for TOP2A copy number evaluation in breast cancer samples. Clin Biochem 43: 891-898, 2010.
    • (2010) Clin Biochem , vol.43 , pp. 891-898
    • Zaczek, A.1    Markiewicz, A.2    Jaskiewicz, J.3
  • 33
    • 77957363057 scopus 로고    scopus 로고
    • Cohesin is limiting for the suppression of DNA damage-induced recombination between homologous chromosomes
    • Covo S, Westmoreland JW, Gordenin DA and Resnick MA: Cohesin is limiting for the suppression of DNA damage-induced recombination between homologous chromosomes. PLoS Genet 6: e1001006, 2010.
    • (2010) PLoS Genet , vol.6
    • Covo, S.1    Westmoreland, J.W.2    Gordenin, D.A.3    Resnick, M.A.4
  • 34
    • 33746515537 scopus 로고    scopus 로고
    • Human SMC5/6 complex promotes sister ch romatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks
    • Potts PR, Porteus MH and Yu H: Human SMC5/6 complex promotes sister ch romatid homologous recombination by recruiting the SMC1/3 cohesin complex to double-strand breaks. EMBO J 25: 3377-3388, 2006.
    • (2006) EMBO J , vol.25 , pp. 3377-3388
    • Potts, P.R.1    Porteus, M.H.2    Yu, H.3
  • 35
    • 79251610008 scopus 로고    scopus 로고
    • Activated leukemic oncogenes AML1-ETO and c-kit: Role in development of acute myeloid leukemia and current approaches for their inhibition
    • Rulina AV, Spirin PV and Prassolov VS: Activated leukemic oncogenes AML1-ETO and c-kit: role in development of acute myeloid leukemia and current approaches for their inhibition. Biochemistry (Mosc) 75: 1650-1666, 2010.
    • (2010) Biochemistry (Mosc) , vol.75 , pp. 1650-1666
    • Rulina, A.V.1    Spirin, P.V.2    Prassolov, V.S.3
  • 36
    • 79954448043 scopus 로고    scopus 로고
    • RUNX1 mutations in acute myeloid leukemia: Results from a comprehensive genetic and clinical analysis from the AML study group
    • Gaidzik VI, Bullinger L, Schlenk RF, et al: RUNX1 mutations in acute myeloid leukemia: results from a comprehensive genetic and clinical analysis from the AML study group. J Clin Oncol 29: 1364-1372, 2011.
    • (2011) J Clin Oncol , vol.29 , pp. 1364-1372
    • Gaidzik, V.I.1    Bullinger, L.2    Schlenk, R.F.3
  • 37
    • 0037226593 scopus 로고    scopus 로고
    • A molecular signature of metastasis in primary solid tumors
    • Ramaswamy S, Ross KN, Lander ES and Golub TR: A molecular signature of metastasis in primary solid tumors. Nat Genet 33: 49-54, 2003.
    • (2003) Nat Genet , vol.33 , pp. 49-54
    • Ramaswamy, S.1    Ross, K.N.2    Lander, E.S.3    Golub, T.R.4
  • 38
    • 77950114803 scopus 로고    scopus 로고
    • Delineating genetic alterations for tumor progression in the MCF10A series of breast cancer cell lines
    • Kadota M, Yang HH, Gomez B, et al: Delineating genetic alterations for tumor progression in the MCF10A series of breast cancer cell lines. PLoS One 5: e9201, 2010.
    • (2010) PLoS One , vol.5
    • Kadota, M.1    Yang, H.H.2    Gomez, B.3
  • 39
    • 29844455237 scopus 로고    scopus 로고
    • Molecular pathology of endometrial carcinoma: Transcriptional signature in endometrioid tumors
    • Abal M, Planaguma J, Gil-Moreno A, et al: Molecular pathology of endometrial carcinoma: transcriptional signature in endometrioid tumors. Histol Histopathol 21: 197-204, 2006.
    • (2006) Histol Histopathol , vol.21 , pp. 197-204
    • Abal, M.1    Planaguma, J.2    Gil-Moreno, A.3
  • 40
    • 29744433336 scopus 로고    scopus 로고
    • Up-regulation of ERM/ETV5 correlates with the degree of myometrial infiltration in endometrioid endometrial carcinoma
    • Planagumà J, Abal M, Gil-Moreno A, et al: Up-regulation of ERM/ETV5 correlates with the degree of myometrial infiltration in endometrioid endometrial carcinoma. J Pathol 207: 422-429, 2005.
    • (2005) J Pathol , vol.207 , pp. 422-429
    • Planagumà, J.1    Abal, M.2    Gil-Moreno, A.3
  • 41
    • 33746074756 scopus 로고    scopus 로고
    • The up-regulation profiles of p21WAF1/CIP1 and RUNX1/AML1 correlate with myometrial infiltration in endometrioid endometrial carcinoma
    • Planagumà J, Gonzalez M, Doll A, et al: The up-regulation profiles of p21WAF1/CIP1 and RUNX1/AML1 correlate with myometrial infiltration in endometrioid endometrial carcinoma. Hum Pathol 37: 1050-1057, 2006.
    • (2006) Hum Pathol , vol.37 , pp. 1050-1057
    • Planagumà, J.1    Gonzalez, M.2    Doll, A.3
  • 42
    • 0027059030 scopus 로고
    • Cloning and characterization of rad21 an essential gene of Schizosaccharomyces pombe involved in DNA double-strand-break repair
    • Birkenbihl RP and Subramani S: Cloning and characterization of rad21 an essential gene of Schizosaccharomyces pombe involved in DNA double-strand-break repair. Nucleic Acids Res 20: 6605-6611, 1992.
    • (1992) Nucleic Acids Res , vol.20 , pp. 6605-6611
    • Birkenbihl, R.P.1    Subramani, S.2
  • 43
    • 0035954251 scopus 로고    scopus 로고
    • Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae
    • Sjögren C and Nasmyth K: Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae. Curr Biol 11: 991-995, 2001.
    • (2001) Curr Biol , vol.11 , pp. 991-995
    • Sjögren, C.1    Nasmyth, K.2


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