-
1
-
-
40449120350
-
An oncogene-induced DNA damage model for cancer development
-
Halazonetis, T. D., Gorgoulis, V. G. & Bartek, J. An oncogene-induced DNA damage model for cancer development. Science 319, 1352-1355 (2008).
-
(2008)
Science
, vol.319
, pp. 1352-1355
-
-
Halazonetis, T.D.1
Gorgoulis, V.G.2
Bartek, J.3
-
2
-
-
60549094865
-
Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites
-
Burrow, A. A., Williams, L. E., Pierce, L. C. & Wang, Y. H. Over half of breakpoints in gene pairs involved in cancer-specific recurrent translocations are mapped to human chromosomal fragile sites. BMC Genomics 10, 59 (2009).
-
(2009)
BMC Genomics
, vol.10
, pp. 59
-
-
Burrow, A.A.1
Williams, L.E.2
Pierce, L.C.3
Wang, Y.H.4
-
3
-
-
33748623634
-
Common fragile sites as targets for chromosome rearrangements
-
(Amst.
-
Arlt, M. F., Durkin, S. G., Ragland, R. L. & Glover, T. W. Common fragile sites as targets for chromosome rearrangements. DNA Repair (Amst.) 5, 1126-1135 (2006).
-
(2006)
DNA Repair
, vol.5
, pp. 1126-1135
-
-
Arlt, M.F.1
Durkin, S.G.2
Ragland, R.L.3
Glover, T.W.4
-
4
-
-
84881615685
-
Common fragile site profiling in epithelial and erythroid cells reveals that most recurrent cancer deletions lie in fragile sites hosting large genes
-
Le Tallec, B. et al. Common fragile site profiling in epithelial and erythroid cells reveals that most recurrent cancer deletions lie in fragile sites hosting large genes. Cell Reports 4, 420-428 (2013).
-
(2013)
Cell Reports
, vol.4
, pp. 420-428
-
-
Le Tallec, B.1
-
5
-
-
84874362586
-
Replication stress links structural and numerical cancer chromosomal instability
-
Burrell, R. A. et al. Replication stress links structural and numerical cancer chromosomal instability. Nature 494, 492-496 (2013).
-
(2013)
Nature
, vol.494
, pp. 492-496
-
-
Burrell, R.A.1
-
6
-
-
0021278143
-
DNA polymerase ? Inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes
-
Glover, T. W., Berger, C., Coyle, J. & Echo, B. DNA polymerase ? inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes. Hum. Genet. 67, 136-142 (1984).
-
(1984)
Hum. Genet.
, vol.67
, pp. 136-142
-
-
Glover, T.W.1
Berger, C.2
Coyle, J.3
Echo, B.4
-
7
-
-
84881439745
-
MUS81 promotes common fragile site expression
-
Ying, S. et al. MUS81 promotes common fragile site expression. Nature Cell Biol. 15, 1001-1007 (2013).
-
(2013)
Nature Cell Biol.
, vol.15
, pp. 1001-1007
-
-
Ying, S.1
-
8
-
-
84881471113
-
ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis
-
Naim, V., Wilhelm, T., Debatisse, M. & Rosselli, F. ERCC1 and MUS81-EME1 promote sister chromatid separation by processing late replication intermediates at common fragile sites during mitosis. Nature Cell Biol. 15, 1008-1015 (2013).
-
(2013)
Nature Cell Biol.
, vol.15
, pp. 1008-1015
-
-
Naim, V.1
Wilhelm, T.2
Debatisse, M.3
Rosselli, F.4
-
9
-
-
84899476646
-
Structure-specific endonucleases: Guardians of fragile site stability
-
Minocherhomji, S. & Hickson, I. D. Structure-specific endonucleases: Guardians of fragile site stability. Trends Cell Biol. 24, 321-327 (2014).
-
(2014)
Trends Cell Biol.
, vol.24
, pp. 321-327
-
-
Minocherhomji, S.1
Hickson, I.D.2
-
10
-
-
0031924605
-
Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: Implications for the mechanism of fragile site induction
-
Le Beau, M. M. et al. Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: Implications for the mechanism of fragile site induction. Hum. Mol. Genet. 7, 755-761 (1998).
-
(1998)
Hum. Mol. Genet.
, vol.7
, pp. 755-761
-
-
Le Beau, M.M.1
-
11
-
-
4344610852
-
Timing and checkpoints in the regulation of mitotic progression
-
Meraldi, P., Draviam, V. M. & Sorger, P. K. Timing and checkpoints in the regulation of mitotic progression. Dev. Cell 7, 45-60 (2004).
-
(2004)
Dev. Cell
, vol.7
, pp. 45-60
-
-
Meraldi, P.1
Draviam, V.M.2
Sorger, P.K.3
-
12
-
-
33746094659
-
Selective small-molecule inhibitor reveals critical mitotic functions of human cdk1
-
Vassilev, L. T. et al. Selective small-molecule inhibitor reveals critical mitotic functions of human CDK1. Proc. Natl Acad. Sci. USA 103, 10660-10665 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 10660-10665
-
-
Vassilev, L.T.1
-
13
-
-
0037059611
-
Nuclear envelope breakdown proceeds by microtubule-induced tearing of the lamina
-
Beaudouin, J., Gerlich, D., Daigle, N., Eils, R. & Ellenberg, J. Nuclear envelope breakdown proceeds by microtubule-induced tearing of the lamina. Cell 108, 83-96 (2002).
-
(2002)
Cell
, vol.108
, pp. 83-96
-
-
Beaudouin, J.1
Gerlich, D.2
Daigle, N.3
Eils, R.4
Ellenberg, J.5
-
14
-
-
67349227137
-
Replication stress induces sister-chromatid bridging at fragile site loci in mitosis
-
Chan, K. L., Palmai-Pallag, T., Ying, S. & Hickson, I. D. Replication stress induces sister-chromatid bridging at fragile site loci in mitosis. Nature Cell Biol. 11, 753-760 (2009).
-
(2009)
Nature Cell Biol.
, vol.11
, pp. 753-760
-
-
Chan, K.L.1
Palmai-Pallag, T.2
Ying, S.3
Hickson, I.D.4
-
15
-
-
35848930133
-
The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks
-
Hanada, K. et al. The structure-specific endonuclease Mus81 contributes to replication restart by generating double-strand DNA breaks. Nature Struct. Mol. Biol. 14, 1096-1104 (2007).
-
(2007)
Nature Struct. Mol. Biol.
, vol.14
, pp. 1096-1104
-
-
Hanada, K.1
-
16
-
-
42449115326
-
Saccharomyces cerevisiae Mus81-Mms4 is a catalytic DNA structure-selective endonuclease
-
Ehmsen, K. T. & Heyer, W.-D. Saccharomyces cerevisiae Mus81-Mms4 is a catalytic, DNA structure-selective endonuclease. Nucleic Acids Res. 36, 2182-2195 (2008).
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 2182-2195
-
-
Ehmsen, K.T.1
Heyer, W.-D.2
-
17
-
-
84886241606
-
Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells
-
Wyatt, H. D., Sarbajna, S., Matos, J. & West, S. C. Coordinated actions of SLX1-SLX4 and MUS81-EME1 for Holliday junction resolution in human cells. Mol. Cell 52, 234-247 (2013).
-
(2013)
Mol. Cell
, vol.52
, pp. 234-247
-
-
Wyatt, H.D.1
Sarbajna, S.2
Matos, J.3
West, S.C.4
-
18
-
-
84886251421
-
Cooperative control of Holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases
-
Castor, D. et al. Cooperative control of Holliday junction resolution and DNA repair by the SLX1 and MUS81-EME1 nucleases. Mol. Cell 52, 221-233 (2013).
-
(2013)
Mol. Cell
, vol.52
, pp. 221-233
-
-
Castor, D.1
-
19
-
-
79952281751
-
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
-
Lukas, C. et al. 53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress. Nature Cell Biol. 13, 243-253 (2011).
-
(2011)
Nature Cell Biol.
, vol.13
, pp. 243-253
-
-
Lukas, C.1
-
20
-
-
79955490586
-
Replication stress induces 53BP1-containing OPT domains in G1 cells
-
Harrigan, J. A. et al. Replication stress induces 53BP1-containing OPT domains in G1 cells. J. Cell Biol. 193, 97-108 (2011).
-
(2011)
J. Cell Biol.
, vol.193
, pp. 97-108
-
-
Harrigan, J.A.1
-
21
-
-
84864752050
-
Condensins: Universal organizers of chromosomes with diverse functions
-
Hirano, T. Condensins: Universal organizers of chromosomes with diverse functions. Genes Dev. 26, 1659-1678 (2012).
-
(2012)
Genes Dev.
, vol.26
, pp. 1659-1678
-
-
Hirano, T.1
-
22
-
-
84885592677
-
Wapl is an essential regulator of chromatin structure and chromosome segregation
-
Tedeschi, A. et al. Wapl is an essential regulator of chromatin structure and chromosome segregation. Nature 501, 564-568 (2013).
-
(2013)
Nature
, vol.501
, pp. 564-568
-
-
Tedeschi, A.1
-
23
-
-
33846931644
-
The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1
-
Lénárt, P. et al. The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1. Curr. Biol. 17, 304-315 (2007).
-
(2007)
Curr. Biol.
, vol.17
, pp. 304-315
-
-
Lénárt, P.1
-
24
-
-
84892743776
-
Break-induced replication repair of damaged forks induces genomic duplications in human cells
-
Costantino, L. et al. Break-induced replication repair of damaged forks induces genomic duplications in human cells. Science 343, 88-91 (2014).
-
(2014)
Science
, vol.343
, pp. 88-91
-
-
Costantino, L.1
-
25
-
-
84882372684
-
Break-induced replication occurs by conservative DNA synthesis
-
Donnianni, R. A. & Symington, L. S. Break-induced replication occurs by conservative DNA synthesis. Proc. Natl Acad. Sci. USA 110, 13475-13480 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 13475-13480
-
-
Donnianni, R.A.1
Symington, L.S.2
-
26
-
-
34547927220
-
Break-induced replication and telomerase-independent telomere maintenance require Pol32
-
Lydeard, J. R., Jain, S., Yamaguchi, M. & Haber, J. E. Break-induced replication and telomerase-independent telomere maintenance require Pol32. Nature 448, 820-823 (2007).
-
(2007)
Nature
, vol.448
, pp. 820-823
-
-
Lydeard, J.R.1
Jain, S.2
Yamaguchi, M.3
Haber, J.E.4
-
27
-
-
84863005628
-
Common variation near CDKN1A POLD3 and SHROOM2 influences colorectal cancer risk
-
Dunlop, M. G. et al. Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Nature Genet. 44, 770-776 (2012).
-
(2012)
Nature Genet.
, vol.44
, pp. 770-776
-
-
Dunlop, M.G.1
-
28
-
-
84964696552
-
TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells
-
Pedersen, R. T., Kruse, T., Nilsson, J., Oestergaard, V. H. & Lisby, M. TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells. J. Cell Biol. 210, 565-582 (2015).
-
(2015)
J. Cell Biol.
, vol.210
, pp. 565-582
-
-
Pedersen, R.T.1
Kruse, T.2
Nilsson, J.3
Oestergaard, V.H.4
Lisby, M.5
-
29
-
-
84885866032
-
Pif1 helicase and Pol? Promote recombination-coupled DNA synthesis via bubble migration
-
Wilson, M. A. et al. Pif1 helicase and Pol? promote recombination-coupled DNA synthesis via bubble migration. Nature 502, 393-396 (2013).
-
(2013)
Nature
, vol.502
, pp. 393-396
-
-
Wilson, M.A.1
-
30
-
-
84885843906
-
Migrating bubble during break-induced replication drives conservative DNA synthesis
-
Saini, N. et al. Migrating bubble during break-induced replication drives conservative DNA synthesis. Nature 502, 389-392 (2013).
-
(2013)
Nature
, vol.502
, pp. 389-392
-
-
Saini, N.1
|