메뉴 건너뛰기




Volumn 20, Issue 14, 2000, Pages 5032-5040

Postcleavage sequence specificity in V(D)J recombination

Author keywords

[No Author keywords available]

Indexed keywords

LYMPHOCYTE ANTIGEN RECEPTOR;

EID: 0033934684     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.20.14.5032-5040.2000     Document Type: Article
Times cited : (24)

References (47)
  • 1
    • 0030887862 scopus 로고    scopus 로고
    • RAG1 and RAG2 form a stable post-cleavage synaptic complex with DNA containing signal ends in V(D)J recombination
    • Agrawal, A., and D. B. Schatz. 1997. RAG1 and RAG2 form a stable post-cleavage synaptic complex with DNA containing signal ends in V(D)J recombination. Cell 89:43-53.
    • (1997) Cell , vol.89 , pp. 43-53
    • Agrawal, A.1    Schatz, D.B.2
  • 2
    • 0031826699 scopus 로고    scopus 로고
    • Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences
    • Akamatsu, Y., and M. A. Oettinger. 1998. Distinct roles of RAG1 and RAG2 in binding the V(D)J recombination signal sequences. Mol. Cell. Biol. 18: 4670-4678.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 4670-4678
    • Akamatsu, Y.1    Oettinger, M.A.2
  • 3
    • 0025642707 scopus 로고
    • Disruption of the human SCL locus by "illegitimate" V-(D)-J recombinase activity
    • Aplan, P. D., D. P. Lombardi, A. M. Ginsberg, J. Cossman, V. L. Bertness, and I. R. Kirsch. 1990. Disruption of the human SCL locus by "illegitimate" V-(D)-J recombinase activity. Science 250:1426-1429.
    • (1990) Science , vol.250 , pp. 1426-1429
    • Aplan, P.D.1    Lombardi, D.P.2    Ginsberg, A.M.3    Cossman, J.4    Bertness, V.L.5    Kirsch, I.R.6
  • 4
    • 0345379607 scopus 로고    scopus 로고
    • A RAG1 and RAG2 tetramer complex is active in cleavage in V(D)J recombination
    • Bailin, T., X. Mo, and M. Sadofsky. 1999. A RAG1 and RAG2 tetramer complex is active in cleavage in V(D)J recombination. Mol. Cell. Biol. 19:4664-4671.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4664-4671
    • Bailin, T.1    Mo, X.2    Sadofsky, M.3
  • 6
    • 0033571736 scopus 로고    scopus 로고
    • Gamma-irradiation directly affects the formation of coding joints in SCID cell lines
    • Binnie, A., S. Olson, G. E. Wu, and S. M. Lewis. 1999. Gamma-irradiation directly affects the formation of coding joints in SCID cell lines. J. Immunol. 163:5418-5426.
    • (1999) J. Immunol. , vol.163 , pp. 5418-5426
    • Binnie, A.1    Olson, S.2    Wu, G.E.3    Lewis, S.M.4
  • 7
    • 0025151168 scopus 로고
    • Site-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemia
    • Brown, L., J.-T. Cheng, Q. Chen, M. J. Siciliano, W. Crist, G. Buchanan, and R. Baer. 1990. Site-specific recombination of the tal-1 gene is a common occurrence in human T cell leukemia. EMBO J. 9:3343-3351.
    • (1990) EMBO J. , vol.9 , pp. 3343-3351
    • Brown, L.1    Cheng, J.-T.2    Chen, Q.3    Siciliano, M.J.4    Crist, W.5    Buchanan, G.6    Baer, R.7
  • 8
    • 0032883119 scopus 로고    scopus 로고
    • Chromatin remodeling directly activates V(D)J recombination
    • Cherry, S. R., and D. Baltimore. 1999. Chromatin remodeling directly activates V(D)J recombination. Proc. Natl. Acad. Sci. USA 96:10788-10793.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 10788-10793
    • Cherry, S.R.1    Baltimore, D.2
  • 9
    • 0033043388 scopus 로고    scopus 로고
    • Disordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: Parallels with E2A-deficient mice
    • Cherrinsky, D. S., X. F. Zhao, D. H. Lam, M. Ellsworth, K. W. Gross, and P. D. Aplan. 1999. Disordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: parallels with E2A-deficient mice. Mol. Cell. Biol. 19:5025-5035.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 5025-5035
    • Cherrinsky, D.S.1    Zhao, X.F.2    Lam, D.H.3    Ellsworth, M.4    Gross, K.W.5    Aplan, P.D.6
  • 10
    • 0001265782 scopus 로고    scopus 로고
    • RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination
    • Difilippantonio, M. J., C. J. McMahan, Q. M. Eastman, E. Spanopoulou, and D. G. Schatz. 1996. RAG1 mediates signal sequence recognition and recruitment of RAG2 in V(D)J recombination. Cell 87:253-262.
    • (1996) Cell , vol.87 , pp. 253-262
    • Difilippantonio, M.J.1    McMahan, C.J.2    Eastman, Q.M.3    Spanopoulou, E.4    Schatz, D.G.5
  • 12
    • 0026687789 scopus 로고
    • The basis for the mechanistic bias for deletional over inversional V(D)J recombination
    • Gauss, G. H., and M. R. Lieber. 1992. The basis for the mechanistic bias for deletional over inversional V(D)J recombination. Genes Dev. 6:1553-1561.
    • (1992) Genes Dev. , vol.6 , pp. 1553-1561
    • Gauss, G.H.1    Lieber, M.R.2
  • 13
    • 0033168204 scopus 로고    scopus 로고
    • Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase
    • Golding, A., S. Chandler, E. Ballestar, A. P. Wolffe, and M. S. Schlissel. 1999. Nucleosome structure completely inhibits in vitro cleavage by the V(D)J recombinase. EMBO J. 18:3712-3723.
    • (1999) EMBO J. , vol.18 , pp. 3712-3723
    • Golding, A.1    Chandler, S.2    Ballestar, E.3    Wolffe, A.P.4    Schlissel, M.S.5
  • 14
    • 0030795764 scopus 로고    scopus 로고
    • A complex of RAG-1 and RAG-2 proteins persists on DNA after single-strand cleavage at V(D)J recombination signal sequences
    • Grawunder, U., and M. R. Lieber. 1997. A complex of RAG-1 and RAG-2 proteins persists on DNA after single-strand cleavage at V(D)J recombination signal sequences. Nucleic Acids Res. 7:1375-1382.
    • (1997) Nucleic Acids Res. , vol.7 , pp. 1375-1382
    • Grawunder, U.1    Lieber, M.R.2
  • 16
    • 0034695658 scopus 로고    scopus 로고
    • Activation of DNA-dependent protein kinase by single-stranded DNA ends
    • Hammarsten, O., L. G. DeFazio, and G. Chu. 2000. Activation of DNA-dependent protein kinase by single-stranded DNA ends. J. Biol. Chem. 275:1541-1550.
    • (2000) J. Biol. Chem. , vol.275 , pp. 1541-1550
    • Hammarsten, O.1    Defazio, L.G.2    Chu, G.3
  • 17
    • 0024691453 scopus 로고
    • V(D)J recombination: A functional definition of the joining signals
    • Hesse, J. E., M. R. Lieber, K. Mizuuchi, and M. Gellert. 1989. V(D)J recombination: a functional definition of the joining signals. Genes Dev. 3:1053-1061.
    • (1989) Genes Dev. , vol.3 , pp. 1053-1061
    • Hesse, J.E.1    Lieber, M.R.2    Mizuuchi, K.3    Gellert, M.4
  • 18
    • 0032084698 scopus 로고    scopus 로고
    • Assembly of a 12/23 paired signal complex: A critical control point in V(D)J recombination
    • Hiom, K., and M. Gellert. 1998. Assembly of a 12/23 paired signal complex: a critical control point in V(D)J recombination. Mol. Cell 1:1011-1019.
    • (1998) Mol. Cell , vol.1 , pp. 1011-1019
    • Hiom, K.1    Gellert, M.2
  • 19
    • 0030964130 scopus 로고    scopus 로고
    • A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage
    • Hiom, K., and M. Gellert. 1997. A stable RAG1-RAG2-DNA complex that is active in V(D)J cleavage. Cell 88:65-72.
    • (1997) Cell , vol.88 , pp. 65-72
    • Hiom, K.1    Gellert, M.2
  • 20
    • 0030880960 scopus 로고    scopus 로고
    • Coding joint formation in a cell-free V(D)J recombination system
    • Leu, R. M. J., Q. M. Eastman, and D. G. Schatz. 1997. Coding joint formation in a cell-free V(D)J recombination system. Immunity 7:303-314.
    • (1997) Immunity , vol.7 , pp. 303-314
    • Leu, R.M.J.1    Eastman, Q.M.2    Schatz, D.G.3
  • 21
    • 0024255703 scopus 로고
    • Novel strand exchanges in V(D)J recombination
    • Lewis, S., J. E. Hesse, K. Mizuuchi, and M. Gellert. 1988. Novel strand exchanges in V(D)J recombination. Cell 55:1099-1107.
    • (1988) Cell , vol.55 , pp. 1099-1107
    • Lewis, S.1    Hesse, J.E.2    Mizuuchi, K.3    Gellert, M.4
  • 22
    • 0028048275 scopus 로고
    • The mechanism of V(D)J joining: Lessons from molecular, immunological, and comparative analyses
    • Lewis, S. M. 1994. The mechanism of V(D)J joining: lessons from molecular, immunological, and comparative analyses. Adv. Immunol. 56:27-150.
    • (1994) Adv. Immunol. , vol.56 , pp. 27-150
    • Lewis, S.M.1
  • 23
    • 0027983024 scopus 로고
    • P nucleotide insertions and the resolution of hairpin DNA structures in mammalian cells
    • Lewis, S. M. 1994. P nucleotide insertions and the resolution of hairpin DNA structures in mammalian cells. Proc. Natl. Acad. Sci. USA 91:1332-1336.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 1332-1336
    • Lewis, S.M.1
  • 24
    • 0030962091 scopus 로고    scopus 로고
    • Cryptic signals and the fidelity of V(D)J joining
    • Lewis, S. M., E. Agard, S. Suh, and L. Czyzyk. 1997. Cryptic signals and the fidelity of V(D)J joining. Mol. Cell. Biol. 17:3125-3136.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 3125-3136
    • Lewis, S.M.1    Agard, E.2    Suh, S.3    Czyzyk, L.4
  • 25
    • 0026052160 scopus 로고
    • Cutting and closing without recombination in V(D)J joining
    • Lewis, S. M., and J. E. Hesse. 1991. Cutting and closing without recombination in V(D)J joining. EMBO J. 10:3631-3639.
    • (1991) EMBO J. , vol.10 , pp. 3631-3639
    • Lewis, S.M.1    Hesse, J.E.2
  • 26
    • 0023801238 scopus 로고
    • The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombination
    • Lieber, M. R., J. E. Hesse, S. Lewis, G. C. Bosma, N. R. Rosenberg, K. Mizuuchi, M. J. Bosma, and M. Gellert. 1988. The defect in murine severe combined immune deficiency: Joining of signal sequences but not coding segments in V(D)J recombination. Cell 55:7-16.
    • (1988) Cell , vol.55 , pp. 7-16
    • Lieber, M.R.1    Hesse, J.E.2    Lewis, S.3    Bosma, G.C.4    Rosenberg, N.R.5    Mizuuchi, K.6    Bosma, M.J.7    Gellert, M.8
  • 27
    • 0031775443 scopus 로고    scopus 로고
    • The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus
    • Matsuda, F., K. Ishii, P. Bourvagnet, K. Kuma, H. Hayashida, T. Miyata. and T. Honjo. 1998. The complete nucleotide sequence of the human immunoglobulin heavy chain variable region locus. J. Exp. Med. 188:2151-2162.
    • (1998) J. Exp. Med. , vol.188 , pp. 2151-2162
    • Matsuda, F.1    Ishii, K.2    Bourvagnet, P.3    Kuma, K.4    Hayashida, H.5    Miyata, T.6    Honjo, T.7
  • 28
    • 0027535651 scopus 로고
    • P nucleotides in V(D)J recombination: A fine-structure analysis
    • Meier, J. T., and S. M. Lewis. 1993. P nucleotides in V(D)J recombination: a fine-structure analysis. Mol. Cell. Biol. 13:1078-1092.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1078-1092
    • Meier, J.T.1    Lewis, S.M.2
  • 29
    • 0030753633 scopus 로고    scopus 로고
    • Cell-free V(D)J recombination
    • Ramdsen, D. A., T. T. Paull, and M. Gellert. 1997. Cell-free V(D)J recombination. Nature 388:488-491.
    • (1997) Nature , vol.388 , pp. 488-491
    • Ramdsen, D.A.1    Paull, T.T.2    Gellert, M.3
  • 30
    • 0028291092 scopus 로고
    • Conservation of sequence in recombination signal sequence spacers
    • Ramsden, D. A., K. Baetz, and G. E. Wu. 1994. Conservation of sequence in recombination signal sequence spacers. Nucleic Acids Res. 22:1785-1796.
    • (1994) Nucleic Acids Res. , vol.22 , pp. 1785-1796
    • Ramsden, D.A.1    Baetz, K.2    Wu, G.E.3
  • 31
    • 0029891597 scopus 로고    scopus 로고
    • Distinct DNA sequence and structure requirements for the two steps of V(D)J recombination signal cleavage
    • Ramsden, D. A., J. F. McBlane, D. C. V. Gent, and M. Gellert. 1996. Distinct DNA sequence and structure requirements for the two steps of V(D)J recombination signal cleavage. EMBO J. 15:3197-3206.
    • (1996) EMBO J. , vol.15 , pp. 3197-3206
    • Ramsden, D.A.1    McBlane, J.F.2    Gent, D.C.V.3    Gellert, M.4
  • 32
    • 0017111732 scopus 로고
    • A quantitative assay for transformation of bone marrow cells by Abelson murine leukemia virus
    • Rosenberg, N., and D. Baltimore. 1976. A quantitative assay for transformation of bone marrow cells by Abelson murine leukemia virus. J. Exp. Med. 143:1453-1463.
    • (1976) J. Exp. Med. , vol.143 , pp. 1453-1463
    • Rosenberg, N.1    Baltimore, D.2
  • 34
    • 0033395080 scopus 로고    scopus 로고
    • Quantification of illegitimate V(D)J recombinase-mediated mutations in lymphocytes of newborns and adults
    • Scheerer, J. B., L. Xi, G. W. Knapp, R. W. Setzer, W. L. Bigbee, and J. C. Fuscoe. 1999. Quantification of illegitimate V(D)J recombinase-mediated mutations in lymphocytes of newborns and adults. Mutat. Res. 431:291-303.
    • (1999) Mutat. Res. , vol.431 , pp. 291-303
    • Scheerer, J.B.1    Xi, L.2    Knapp, G.W.3    Setzer, R.W.4    Bigbee, W.L.5    Fuscoe, J.C.6
  • 35
    • 0031171282 scopus 로고    scopus 로고
    • Accessibility and the developmental regulation of V(D)J recombination
    • Schlissel, M. S., and P. Stanhope-Baker. 1997. Accessibility and the developmental regulation of V(D)J recombination. Semin. Immunol. 9:161-170.
    • (1997) Semin. Immunol. , vol.9 , pp. 161-170
    • Schlissel, M.S.1    Stanhope-Baker, P.2
  • 36
    • 0027410476 scopus 로고
    • V(D)J recombination: Signal and coding joint resolution are uncoupled and depend on parallel synapsis of the sites
    • Sheehan, K. M., and M. R. Lieber. 1993. V(D)J recombination: signal and coding joint resolution are uncoupled and depend on parallel synapsis of the sites. Mol. Cell. Biol. 13:1363-1370.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 1363-1370
    • Sheehan, K.M.1    Lieber, M.R.2
  • 37
    • 0032973315 scopus 로고    scopus 로고
    • DNA hairpin opening mediated by the RAG1 and RAG2 proteins
    • Shockett, P. E., and D. G. Schatz. 1999. DNA hairpin opening mediated by the RAG1 and RAG2 proteins. Mol. Cell. Biol. 19:4159-4156.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 4159-14156
    • Shockett, P.E.1    Schatz, D.G.2
  • 38
    • 0021089697 scopus 로고
    • Energetics of DNA twisting. II. Topoisomer analysis
    • Shore, D., and R. L. Baldwin. 1983. Energetics of DNA twisting. II. Topoisomer analysis. J. Mol. Biol. 170:983-1007.
    • (1983) J. Mol. Biol. , vol.170 , pp. 983-1007
    • Shore, D.1    Baldwin, R.L.2
  • 39
    • 0001191247 scopus 로고
    • DNA flexibility studied by covalent closure of short fragments into circles
    • Shore, D., J. Langowski, and R. L. Baldwin. 1981. DNA flexibility studied by covalent closure of short fragments into circles. Proc. Natl. Acad. Sci. USA 78:4833-4837.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 4833-4837
    • Shore, D.1    Langowski, J.2    Baldwin, R.L.3
  • 40
    • 0029983727 scopus 로고    scopus 로고
    • Accessibility control of antigen-receptor variable-region gene assembly: Role of cis-acting elements
    • Sleckman, B. P., J. R. German, and F. W. Alt. 1996. Accessibility control of antigen-receptor variable-region gene assembly: role of cis-acting elements. Annu. Rev. Immunol. 14:459-481.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 459-481
    • Sleckman, B.P.1    German, J.R.2    Alt, F.W.3
  • 41
    • 0031741234 scopus 로고    scopus 로고
    • Failure of hairpin-ended and nicked DNA to activate DNA-dependent protein kinase: Implications for V(D)J recombination
    • Smider, V., W. K. Rathmell, G. Brown, S. Lewis, and G. Chu. 1998. Failure of hairpin-ended and nicked DNA to activate DNA-dependent protein kinase: implications for V(D)J recombination. Mol. Cell. Biol. 18:6853-6858.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 6853-6858
    • Smider, V.1    Rathmell, W.K.2    Brown, G.3    Lewis, S.4    Chu, G.5
  • 43
    • 0032913232 scopus 로고    scopus 로고
    • Roles of the "dispensable" portions of RAG-1 and RAG-2 in V(D)J recombination
    • Steen, S. B., J. O. Han, C. Mundy, M. A. Oettinger, and D. B. Roth. 1999. Roles of the "dispensable" portions of RAG-1 and RAG-2 in V(D)J recombination. Mol. Cell. Biol. 19:3010-3017.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 3010-3017
    • Steen, S.B.1    Han, J.O.2    Mundy, C.3    Oettinger, M.A.4    Roth, D.B.5
  • 44
    • 0032126295 scopus 로고    scopus 로고
    • V(D)J recombination signal recognition: Distinct, overlapping DNA-protein contacts in complexes containing RAG1 with and without RAG2
    • Swanson, P. C., and S. Desiderio. 1998. V(D)J recombination signal recognition: Distinct, overlapping DNA-protein contacts in complexes containing RAG1 with and without RAG2. Immunity 9:115-125.
    • (1998) Immunity , vol.9 , pp. 115-125
    • Swanson, P.C.1    Desiderio, S.2
  • 45
    • 0020534965 scopus 로고
    • Somatic generation of antibody diversity
    • Tonegawa, S. 1983. Somatic generation of antibody diversity. Nature 302: 575-581.
    • (1983) Nature , vol.302 , pp. 575-581
    • Tonegawa, S.1
  • 46
    • 0033103012 scopus 로고    scopus 로고
    • Control of V(D)J recombinational accessibility of the D beta 1 gene segment at the TCR beta locus by a germline promoter
    • Whitehurst, C. E., S. Chattopadhyay, and J. Chen. 1999. Control of V(D)J recombinational accessibility of the D beta 1 gene segment at the TCR beta locus by a germline promoter. Immunity 10:313-322.
    • (1999) Immunity , vol.10 , pp. 313-322
    • Whitehurst, C.E.1    Chattopadhyay, S.2    Chen, J.3
  • 47
    • 0032718391 scopus 로고    scopus 로고
    • Flanking nuclear matrix attachment regions synergize with the T cell receptor delta enhancer to promote V(D)J recombination
    • Zhong, X. P., J. Carabana, and M. S. Krangel. 1999. Flanking nuclear matrix attachment regions synergize with the T cell receptor delta enhancer to promote V(D)J recombination. Proc. Natl. Acad. Sci. USA 96:11970-11975.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 11970-11975
    • Zhong, X.P.1    Carabana, J.2    Krangel, M.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.