Therapeutic potential of foldamers: From chemical biology tools to drug candidates?

Journal of Medicinal Chemistry

Volumn 59, Issue 21, 2016, Pages 9599-9621

  Gopalakrishnan, Ranganath ^a,b   Frolov, Andrey I ^a   Knerr, Laurent ^a   Drury, William J ^a   Valeur, Eric ^a  

^a ASTRAZENECA R AND D   (Sweden)

^b MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; ANTIBIOTIC AGENT; ANTINEOPLASTIC AGENT; BETA AMINO ACID; CELL PENETRATING PEPTIDE; CHOLESTEROL; DRUG; FOLDAMER; GAMMA AMINO ACID; HYPOXIA INDUCIBLE FACTOR 1; LUNG SURFACTANT PROTEIN; OLIGOMER; PEPTIDE HORMONE; PEPTOID; PIPERAZINE DERIVATIVE; POLYSACCHARIDE SULFATE; PROTEIN; PROTEIN BCL 2; UNCLASSIFIED DRUG; UREA; PEPTIDE; POLYCYCLIC AROMATIC HYDROCARBON;

ARTICLE; CHEMICAL INTERACTION; DNA BINDING; DRUG DEVELOPMENT; ENCAPSULATION; MOLECULAR MODEL; NONHUMAN; PDZ DOMAIN; PROTEIN AGGREGATION; PROTEIN PROTEIN INTERACTION; VIRUS ENTRY; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; HUMAN; PROTEIN FOLDING;

DRUG DISCOVERY; HUMANS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PEPTIDES; POLYCYCLIC AROMATIC HYDROCARBONS; PROTEIN FOLDING;

EID: 84994852259     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/acs.jmedchem.6b00376     Document Type: Article

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