-
1
-
-
0037155199
-
PDZ domains: Structural modules for protein complex assembly
-
Hung, A. Y. & Sheng, M. PDZ domains: structural modules for protein complex assembly. J. Biol. Chem. 277, 5699-5702 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 5699-5702
-
-
Hung, A.Y.1
Sheng, M.2
-
2
-
-
2442602096
-
MAGUKs in synapse assembly and function: An emerging view
-
Montgomery, J. M., Zamorano, P. L. & Garner, C. C. MAGUKs in synapse assembly and function: an emerging view. Cell. Mol. Life Sci. 61, 911-929 (2004).
-
(2004)
Cell. Mol. Life Sci.
, vol.61
, pp. 911-929
-
-
Montgomery, J.M.1
Zamorano, P.L.2
Garner, C.C.3
-
3
-
-
0037320688
-
Assembly and plasticity of the glutamatergic postsynaptic specialization
-
McGee, A. W. & Bredt, D. S. Assembly and plasticity of the glutamatergic postsynaptic specialization. Curr. Opin. Neurobiol. 13, 111-118 (2003).
-
(2003)
Curr. Opin. Neurobiol.
, vol.13
, pp. 111-118
-
-
McGee, A.W.1
Bredt, D.S.2
-
4
-
-
0034916230
-
PDZ domains and the organization of supramolecular complexes
-
Sheng, M. & Sala, C. PDZ domains and the organization of supramolecular complexes. Annu. Rev. Neurosci. 24, 1-29 (2001).
-
(2001)
Annu. Rev. Neurosci.
, vol.24
, pp. 1-29
-
-
Sheng, M.1
Sala, C.2
-
5
-
-
0037174634
-
Postsynaptic signaling and plasticity mechanisms
-
Sheng, M. & Kim, M. J. Postsynaptic signaling and plasticity mechanisms. Science 298, 776-780 (2002).
-
(2002)
Science
, vol.298
, pp. 776-780
-
-
Sheng, M.1
Kim, M.J.2
-
6
-
-
0035697173
-
Structure of the SH3-guanylate kinase module from PSD-95 suggests a mechanism for regulated assembly of MAGUK scaffolding proteins
-
McGee, A. W. et al. Structure of the SH3-guanylate kinase module from PSD-95 suggests a mechanism for regulated assembly of MAGUK scaffolding proteins. Mol. Cell 8, 1291-1301 (2001).
-
(2001)
Mol. Cell
, vol.8
, pp. 1291-1301
-
-
McGee, A.W.1
-
7
-
-
0035695024
-
Structural characterization of the intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95
-
Tavares, G. A., Panepucci, E. H. & Brunger, A. T. Structural characterization of the intramolecular interaction between the SH3 and guanylate kinase domains of PSD-95. Mol. Cell 8, 1313-1325 (2001).
-
(2001)
Mol. Cell
, vol.8
, pp. 1313-1325
-
-
Tavares, G.A.1
Panepucci, E.H.2
Brunger, A.T.3
-
8
-
-
0037436384
-
Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95
-
Long, J. F. et al. Supramodular structure and synergistic target binding of the N-terminal tandem PDZ domains of PSD-95. J. Mol. Biol. 327, 203-214 (2003). The structure of the first two PDZ domains of PSD-95 was determined by NMR, suggesting a model in which the tandem PDZ domains are oriented in a similar direction to promote interaction with pairs of C termini extending from oligomeric membrane receptors or ion channels.
-
(2003)
J. Mol. Biol.
, vol.327
, pp. 203-214
-
-
Long, J.F.1
-
9
-
-
0032898374
-
Requirement of N-terminal cysteines of PSD-95 for PSD-95 multimerization and ternary complex formation, but not for binding to potassium channel Kv1.4
-
Hsueh, Y. P. & Sheng, M. Requirement of N-terminal cysteines of PSD-95 for PSD-95 multimerization and ternary complex formation, but not for binding to potassium channel Kv1.4. J. Biol. Chem. 274, 532-536 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 532-536
-
-
Hsueh, Y.P.1
Sheng, M.2
-
10
-
-
0042386445
-
Lipid- and protein-mediated multimerization of PSD-95: Implications for receptor clustering and assembly of synaptic protein networks
-
Christopherson, K. S. et al. Lipid- and protein-mediated multimerization of PSD-95: implications for receptor clustering and assembly of synaptic protein networks. J. Cell Sci. 116, 3213-3219 (2003).
-
(2003)
J. Cell Sci.
, vol.116
, pp. 3213-3219
-
-
Christopherson, K.S.1
-
11
-
-
0037424515
-
Crystal structure of GRIP1 PDZ6-peptide complex reveals the structural basis for class II PDZ target recognition and PDZ domain-mediated multimerization
-
Im, Y. J. et al. Crystal structure of GRIP1 PDZ6-peptide complex reveals the structural basis for class II PDZ target recognition and PDZ domain-mediated multimerization. J. Biol. Chem. 278, 8501-8507 (2002).
-
(2002)
J. Biol. Chem.
, vol.278
, pp. 8501-8507
-
-
Im, Y.J.1
-
12
-
-
0035865546
-
Laminar organization of the NMDA receptor complex within the postsynaptic density
-
Valtschanoff, J. G. & Weinberg, R. J. Laminar organization of the NMDA receptor complex within the postsynaptic density. J. Neurosci. 21, 1211-1217 (2001).
-
(2001)
J. Neurosci.
, vol.21
, pp. 1211-1217
-
-
Valtschanoff, J.G.1
Weinberg, R.J.2
-
13
-
-
0348010289
-
2+/ calmodulin-dependent protein kinase II at the PSD
-
2+/calmodulin-dependent protein kinase II at the PSD. J. Neurosci. 23, 11270-11278 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 11270-11278
-
-
Petersen, J.D.1
-
15
-
-
0032608712
-
Assembly and maturation of the Drosophila larval neuromuscular junction
-
Gramates, L. S. & Budnik, V. Assembly and maturation of the Drosophila larval neuromuscular junction. Int. Rev. Neurobiol. 43, 93-117 (1999).
-
(1999)
Int. Rev. Neurobiol.
, vol.43
, pp. 93-117
-
-
Gramates, L.S.1
Budnik, V.2
-
16
-
-
0032481058
-
Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein
-
Migaud, M. et al. Enhanced long-term potentiation and impaired learning in mice with mutant postsynaptic density-95 protein. Nature 396, 433-439 (1998).
-
(1998)
Nature
, vol.396
, pp. 433-439
-
-
Migaud, M.1
-
17
-
-
0032559283
-
Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo
-
Sprengel, R. et al. Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo. Cell 92, 279-289 (1998).
-
(1998)
Cell
, vol.92
, pp. 279-289
-
-
Sprengel, R.1
-
18
-
-
0033492575
-
Microtubule binding by CRIPT and its potential role in the synaptic clustering of PSD-95
-
Passafaro, M., Sala, C., Niethammer, M. & Sheng, M. Microtubule binding by CRIPT and its potential role in the synaptic clustering of PSD-95. Nature Neurosci. 2, 1063-1069 (1999).
-
(1999)
Nature Neurosci.
, vol.2
, pp. 1063-1069
-
-
Passafaro, M.1
Sala, C.2
Niethammer, M.3
Sheng, M.4
-
19
-
-
0034659803
-
C-terminal truncation of NR2A subunits impairs synaptic but not extrasynaptic localization of NMDA receptors
-
Steigerwald, F. et al. C-terminal truncation of NR2A subunits impairs synaptic but not extrasynaptic localization of NMDA receptors. J. Neurosci. 20, 4573-4581 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 4573-4581
-
-
Steigerwald, F.1
-
20
-
-
0037109723
-
Relationship between availability of NMDA receptor subunits and their expression at the synapse
-
Prybylowski, K. et al. Relationship between availability of NMDA receptor subunits and their expression at the synapse. J. Neurosci. 22, 8902-8910 (2002).
-
(2002)
J. Neurosci.
, vol.22
, pp. 8902-8910
-
-
Prybylowski, K.1
-
21
-
-
0037130451
-
Subunit-specific NMDA receptor trafficking to synapses
-
Barria, A. & Malinow, R. Subunit-specific NMDA receptor trafficking to synapses. Neuron 35, 345-353 (2002).
-
(2002)
Neuron
, vol.35
, pp. 345-353
-
-
Barria, A.1
Malinow, R.2
-
22
-
-
0032168178
-
Role of the carboxy-terminal region of the GluR ε2 subunit in synaptic localization of the NMDA receptor channel
-
Mori, H. et al. Role of the carboxy-terminal region of the GluR ε2 subunit in synaptic localization of the NMDA receptor channel. Neuron 21, 571-580 (1998).
-
(1998)
Neuron
, vol.21
, pp. 571-580
-
-
Mori, H.1
-
23
-
-
0034941552
-
Molecular determinants of NMDA receptor internalization
-
Roche, K. W. et al. Molecular determinants of NMDA receptor internalization. Nature Neurosci. 4, 794-802 (2001).
-
(2001)
Nature Neurosci.
, vol.4
, pp. 794-802
-
-
Roche, K.W.1
-
24
-
-
0033966213
-
Internalization of the Kv1.4 potassium channel is suppressed by clustering interactions with PSD-95
-
Jugloff, D. G., Khanna, R., Schlichter, L. C. & Jones, O. T. Internalization of the Kv1.4 potassium channel is suppressed by clustering interactions with PSD-95. J. Biol. Chem. 275, 1357-1364. (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 1357-1364
-
-
Jugloff, D.G.1
Khanna, R.2
Schlichter, L.C.3
Jones, O.T.4
-
25
-
-
0034623942
-
β1-adrenergic receptor association with PSD-95. Inhibition of receptor internalization and facilitation of β1-adrenergic receptor interaction with N-methyl-D-aspartate receptors
-
Hu, L. A. et al. β1-adrenergic receptor association with PSD-95. Inhibition of receptor internalization and facilitation of β1-adrenergic receptor interaction with N-methyl-D-aspartate receptors. J. Biol. Chem. 275, 38659-38666 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 38659-38666
-
-
Hu, L.A.1
-
26
-
-
0030770840
-
Binding of neuroligins to PSD-95
-
Irie, M. et al. Binding of neuroligins to PSD-95. Science 277, 1511-1515 (1997).
-
(1997)
Science
, vol.277
, pp. 1511-1515
-
-
Irie, M.1
-
27
-
-
0037200037
-
SynCAM, a synaptic adhesion molecule that drives synapse assembly
-
Biederer, T. et al. SynCAM, a synaptic adhesion molecule that drives synapse assembly. Science 297, 1525-1531 (2002). This paper identifies SynCAM, a homophilic cell-adhesion molecule of the immunoglobulin superfamily located on both sides of the synapse, which promotes synapse formation by interacting with cytoplasmic PDZ proteins.
-
(2002)
Science
, vol.297
, pp. 1525-1531
-
-
Biederer, T.1
-
28
-
-
0037743572
-
Neurexin mediates the assembly of presynaptic terminals
-
Dean, C. et al. Neurexin mediates the assembly of presynaptic terminals. Nature Neurosci. 6, 708-716 (2003). This paper reports that the neuroligin-β-neurexin complex induces presynaptic assembly by two steps: clustering of presynaptic β-neurexin by interaction with oligomeric neuroligin, and recruitment of presynaptic molecules through the PDZ-binding C terminus of β-neurexin.
-
(2003)
Nature Neurosci.
, vol.6
, pp. 708-716
-
-
Dean, C.1
-
29
-
-
0032514263
-
Direct interaction of CASK/LIN-2 and syndecan heparan sulfate proteoglycan and their overlapping distribution in neuronal synapses
-
Hsueh, Y. P. et al. Direct interaction of CASK/LIN-2 and syndecan heparan sulfate proteoglycan and their overlapping distribution in neuronal synapses. J. Cell. Biol. 142, 139-151 (1998).
-
(1998)
J. Cell. Biol.
, vol.142
, pp. 139-151
-
-
Hsueh, Y.P.1
-
30
-
-
0242551549
-
Some assembly required: The development of neuronal synapses
-
Li, Z. & Sheng, M. Some assembly required: the development of neuronal synapses. Nature Rev. Mol. Cell Biol. 4, 833-841 (2003).
-
(2003)
Nature Rev. Mol. Cell Biol.
, vol.4
, pp. 833-841
-
-
Li, Z.1
Sheng, M.2
-
31
-
-
0242656298
-
FASt remodeling of synapses in Drosophila
-
Packard, M., Mathew, D. & Budnik, V. FASt remodeling of synapses in Drosophila. Curr. Opin. Neurobiol. 13, 527-534 (2003).
-
(2003)
Curr. Opin. Neurobiol.
, vol.13
, pp. 527-534
-
-
Packard, M.1
Mathew, D.2
Budnik, V.3
-
32
-
-
0033995266
-
+ channels differentially couple to PDZ proteins of the PSD-95/SAP 90 family
-
+ channels differentially couple to PDZ proteins of the PSD-95/SAP90 family. J. Neurosci. 20, 156-162 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 156-162
-
-
Nehring, R.B.1
-
33
-
-
13344277364
-
Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and α1-syntrophin mediated by PDZ domains
-
Brenman, J. E. et al. Interaction of nitric oxide synthase with the postsynaptic density protein PSD-95 and α1-syntrophin mediated by PDZ domains. Cell 84, 757-767 (1996).
-
(1996)
Cell
, vol.84
, pp. 757-767
-
-
Brenman, J.E.1
-
34
-
-
0037174635
-
Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions
-
Aarts, M. et al. Treatment of ischemic brain damage by perturbing NMDA receptor-PSD-95 protein interactions. Science 298, 846-850 (2002). A synthetic peptide that mimics the PDZ-binding C terminus of an NMDAR subunit (NR2B) blocks NMDA-induced excitotoxicity without affecting NMDAR function, suggesting the therapeutic potential of this approach in stroke treatment.
-
(2002)
Science
, vol.298
, pp. 846-850
-
-
Aarts, M.1
-
35
-
-
0032078872
-
A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II
-
Chen, H. J., Rojas-Soto, M., Oguni, A. & Kennedy, M. B. A synaptic Ras-GTPase activating protein (p135 SynGAP) inhibited by CaM kinase II. Neuron 20, 895-904 (1998).
-
(1998)
Neuron
, vol.20
, pp. 895-904
-
-
Chen, H.J.1
Rojas-Soto, M.2
Oguni, A.3
Kennedy, M.B.4
-
36
-
-
0032055396
-
SynGAP: A synaptic RasGAP that associates with the PSD-95/SAP90 protein family
-
Kim, J. H., Liao, D., Lau, L. F. & Huganir, R. L. SynGAP: a synaptic RasGAP that associates with the PSD-95/SAP90 protein family. Neuron 20, 683-691 (1998).
-
(1998)
Neuron
, vol.20
, pp. 683-691
-
-
Kim, J.H.1
Liao, D.2
Lau, L.F.3
Huganir, R.L.4
-
38
-
-
0037162696
-
Ras and Rap control AMPA receptor trafficking during synaptic plasticity
-
Zhu, J. J., Qin, Y., Zhao, M., Van Aelst, L. & Malinow, R. Ras and Rap control AMPA receptor trafficking during synaptic plasticity. Cell 110, 443-455 (2002).
-
(2002)
Cell
, vol.110
, pp. 443-455
-
-
Zhu, J.J.1
Qin, Y.2
Zhao, M.3
Van Aelst, L.4
Malinow, R.5
-
39
-
-
0037111835
-
SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor
-
Komiyama, N. H. et al. SynGAP regulates ERK/MAPK signaling, synaptic plasticity, and learning in the complex with postsynaptic density 95 and NMDA receptor. J. Neurosci. 22, 9721-9732 (2002).
-
(2002)
J. Neurosci.
, vol.22
, pp. 9721-9732
-
-
Komiyama, N.H.1
-
40
-
-
0037442509
-
The role of synaptic GTPase-activating protein in neuronal development and synaptic plasticity
-
Kim, J. H., Lee, H. K., Takamiya, K. & Huganir, R. L. The role of synaptic GTPase-activating protein in neuronal development and synaptic plasticity. J. Neurosci. 23, 1119-1124 (2003). References 39 and 40, studies on SynGAP-deficient mice, report that SynGAP, a PSD-95-binding GAP for Ras, regulates the MAP kinase pathway, synaptic AMPAR clustering, LTP and spatial learning.
-
(2003)
J. Neurosci.
, vol.23
, pp. 1119-1124
-
-
Kim, J.H.1
Lee, H.K.2
Takamiya, K.3
Huganir, R.L.4
-
41
-
-
0033671742
-
Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex
-
Colledge, M. et al. Targeting of PKA to glutamate receptors through a MAGUK-AKAP complex. Neuron 27, 107 (2000).
-
(2000)
Neuron
, vol.27
, pp. 107
-
-
Colledge, M.1
-
42
-
-
0037092436
-
Regulation of GluR1 by the A-kinase anchoring protein 79 (AKAP79) signaling complex shares properties with long-term depression
-
Tavalin, S. J. et al. Regulation of GluR1 by the A-kinase anchoring protein 79 (AKAP79) signaling complex shares properties with long-term depression. J. Neurosci. 22, 3044-3051 (2002).
-
(2002)
J. Neurosci.
, vol.22
, pp. 3044-3051
-
-
Tavalin, S.J.1
-
43
-
-
0033639083
-
Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting
-
Ehlers, M. D. Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting. Neuron 28, 511-525 (2000).
-
(2000)
Neuron
, vol.28
, pp. 511-525
-
-
Ehlers, M.D.1
-
44
-
-
0034702259
-
Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity
-
Lee, H. K., Barbarosie, M., Kameyama, K., Bear, M. F. & Huganir, R. L. Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity. Nature 405, 955-959 (2000).
-
(2000)
Nature
, vol.405
, pp. 955-959
-
-
Lee, H.K.1
Barbarosie, M.2
Kameyama, K.3
Bear, M.F.4
Huganir, R.L.5
-
45
-
-
0032215153
-
Involvement of a postsynaptic protein kinase A substrate in the expression of homosynaptic long-term depression
-
Kameyama, K., Lee, H. K., Bear, M. F. & Huganir, R. L. Involvement of a postsynaptic protein kinase A substrate in the expression of homosynaptic long-term depression. Neuron 21, 1163-1175 (1998).
-
(1998)
Neuron
, vol.21
, pp. 1163-1175
-
-
Kameyama, K.1
Lee, H.K.2
Bear, M.F.3
Huganir, R.L.4
-
46
-
-
1842731881
-
Src kinases: A hub for NMDA receptor regulation
-
Salter, M. W. & Kalia, L. V. Src kinases: a hub for NMDA receptor regulation. Nature Rev. Neurosci. 5, 317-328 (2004).
-
(2004)
Nature Rev. Neurosci.
, vol.5
, pp. 317-328
-
-
Salter, M.W.1
Kalia, L.V.2
-
47
-
-
12144288368
-
Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD
-
Ahmadian, G. et al. Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD. EMBO J. 23, 1040-1050 (2004).
-
(2004)
EMBO J.
, vol.23
, pp. 1040-1050
-
-
Ahmadian, G.1
-
48
-
-
1542614147
-
Interactions between Src family protein tyrosine kinases and PSD-95
-
Kalia, L. V. & Salter, M. W. Interactions between Src family protein tyrosine kinases and PSD-95. Neuropharmacology 45, 720-728 (2003).
-
(2003)
Neuropharmacology
, vol.45
, pp. 720-728
-
-
Kalia, L.V.1
Salter, M.W.2
-
49
-
-
0033582266
-
PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A
-
Tezuka, T., Umemori, H., Akiyama, T., Nakanishi, S. & Yamamoto, T. PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A. Proc. Natl Acad. Sci. USA 96, 435-440 (1999).
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 435-440
-
-
Tezuka, T.1
Umemori, H.2
Akiyama, T.3
Nakanishi, S.4
Yamamoto, T.5
-
50
-
-
17744380787
-
CAKβ/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus
-
Huang, Y. et al. CAKβ/Pyk2 kinase is a signaling link for induction of long-term potentiation in CA1 hippocampus. Neuron 29, 485-496 (2001).
-
(2001)
Neuron
, vol.29
, pp. 485-496
-
-
Huang, Y.1
-
51
-
-
0035654078
-
Dendritic spines: Structure, dynamics and regulation
-
Hering, H. & Sheng, M. Dendritic spines: structure, dynamics and regulation. Nature Rev. Neurosci. 2, 880-888 (2001).
-
(2001)
Nature Rev. Neurosci.
, vol.2
, pp. 880-888
-
-
Hering, H.1
Sheng, M.2
-
52
-
-
0037068824
-
Spine motility. Phenomenology, mechanisms, and function
-
Bonhoeffer, T. & Yuste, R. Spine motility. Phenomenology, mechanisms, and function. Neuron 35, 1019-1027 (2002).
-
(2002)
Neuron
, vol.35
, pp. 1019-1027
-
-
Bonhoeffer, T.1
Yuste, R.2
-
53
-
-
0035139220
-
The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis
-
Penzes, P. et al. The neuronal Rho-GEF Kalirin-7 interacts with PDZ domain-containing proteins and regulates dendritic morphogenesis. Neuron 29, 229-242 (2001).
-
(2001)
Neuron
, vol.29
, pp. 229-242
-
-
Penzes, P.1
-
54
-
-
0037461752
-
Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin
-
Penzes, P. et al. Rapid induction of dendritic spine morphogenesis by trans-synaptic ephrinB-EphB receptor activation of the Rho-GEF kalirin. Neuron 37, 263-274 (2003). Activation of EphB receptors by their ephrinB ligand stimulates Kalirin-7, a PSD-95-binding guanine nucleotide exchange factor (GEF) for Rac1, and promotes spine formation through a signalling pathway that involves Rac1 and PAK.
-
(2003)
Neuron
, vol.37
, pp. 263-274
-
-
Penzes, P.1
-
55
-
-
0037127073
-
Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors
-
Takasu, M. A., Dalva, M. B., Zigmond, R. E. & Greenberg, M. E. Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors. Science 295, 491-495 (2002).
-
(2002)
Science
, vol.295
, pp. 491-495
-
-
Takasu, M.A.1
Dalva, M.B.2
Zigmond, R.E.3
Greenberg, M.E.4
-
56
-
-
2442683994
-
Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry
-
Peng, J. et al. Semiquantitative proteomic analysis of rat forebrain postsynaptic density fractions by mass spectrometry. J. Biol. Chem. 217, 21003-21011 (2004). As well as identifying approximately 400 proteins in the PSD fraction, this paper uses quantitative mass spectrometry to measure the relative abundance in molar terms of key proteins of the PSD, including PSD-95, GKAP, Shank1, NMDAR (NR1) and AMPAR (GluR1 and GluR2).
-
(2004)
J. Biol. Chem.
, vol.217
, pp. 21003-21011
-
-
Peng, J.1
-
57
-
-
0344443828
-
Targeted protein degradation and synapse remodeling by an inducible protein kinase
-
Pak, D. T. & Sheng, M. Targeted protein degradation and synapse remodeling by an inducible protein kinase. Science 302, 1368-1373 (2003). SNK, a protein kinase induced by synaptic activity, binds to and phosphorylates SPAR, a postsynaptic GAP for the small GTPase Rap, leading to degradation of SPAR by the ubiquitin-proteasome pathway, and resulting in activity-dependent loss of synapses and spines.
-
(2003)
Science
, vol.302
, pp. 1368-1373
-
-
Pak, D.T.1
Sheng, M.2
-
58
-
-
0034680745
-
PSD-95 involvement in maturation of excitatory synapses
-
El-Husseini, A. E., Schnell, E., Chetkovich, D. M., Nicoll, R. A. & Bredt, D. S. PSD-95 involvement in maturation of excitatory synapses. Science 290, 1364-1368 (2000).
-
(2000)
Science
, vol.290
, pp. 1364-1368
-
-
El-Husseini, A.E.1
Schnell, E.2
Chetkovich, D.M.3
Nicoll, R.A.4
Bredt, D.S.5
-
59
-
-
0034044563
-
The Shank family of scaffold proteins
-
Sheng, M. & Kim, E. The Shank family of scaffold proteins. J. Cell Sci. 113, 1851-1856 (2000).
-
(2000)
J. Cell Sci.
, vol.113
, pp. 1851-1856
-
-
Sheng, M.1
Kim, E.2
-
60
-
-
0026492629
-
The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein
-
Cho, K. O., Hunt, C. A. & Kennedy, M. B. The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein. Neuron 9, 929-942 (1992).
-
(1992)
Neuron
, vol.9
, pp. 929-942
-
-
Cho, K.O.1
Hunt, C.A.2
Kennedy, M.B.3
-
61
-
-
0038045645
-
Postsynaptic density-95 mimics and occludes hippocampal long-term potentiation and enhances long-term depression
-
Stein, V., House, D. R., Bredt, D. S. & Nicoll, R. A. Postsynaptic density-95 mimics and occludes hippocampal long-term potentiation and enhances long-term depression. J. Neurosci. 23, 5503-5506 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 5503-5506
-
-
Stein, V.1
House, D.R.2
Bredt, D.S.3
Nicoll, R.A.4
-
62
-
-
0037319324
-
PSD-95 regulates synaptic transmission and plasticity in rat cerebral cortex
-
Beique, J. C. & Andrade, R. PSD-95 regulates synaptic transmission and plasticity in rat cerebral cortex. J. Physiol. 546, 859-867 (2003).
-
(2003)
J. Physiol.
, vol.546
, pp. 859-867
-
-
Beique, J.C.1
Andrade, R.2
-
63
-
-
0742322856
-
Postsynaptic density 95 controls AMPA receptor incorporation during long-term potentiation and experience-driven synaptic plasticity
-
Ehrlich, I. & Malinow, R. Postsynaptic density 95 controls AMPA receptor incorporation during long-term potentiation and experience-driven synaptic plasticity. J. Neurosci. 24, 916-927 (2004). References 61-63 demonstrate a central role for PSD-95 in the control of synaptic abundance of AMPARs and synaptic plasticity based on electrophysiological experiments in brain slices transfected with PSD-95 constructs.
-
(2004)
J. Neurosci.
, vol.24
, pp. 916-927
-
-
Ehrlich, I.1
Malinow, R.2
-
64
-
-
0034700490
-
Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms
-
Chen, L. et al. Stargazin regulates synaptic targeting of AMPA receptors by two distinct mechanisms. Nature 408, 936-943 (2000). Stargazin, an AMPAR- and PSD-95-associated membrane protein, is shown to promote synaptic AMPAR targeting by two distinct mechanisms: surface expression and synaptic targeting.
-
(2000)
Nature
, vol.408
, pp. 936-943
-
-
Chen, L.1
-
65
-
-
0037109042
-
Direct interactions between PSD-95 and stargazin control synaptic AMPA receptor number
-
Schnell, E. et al. Direct interactions between PSD-95 and stargazin control synaptic AMPA receptor number. Proc. Natl Acad. Sci. USA 99, 13902-13907 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 13902-13907
-
-
Schnell, E.1
-
66
-
-
1342312287
-
Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity
-
Yao, W. D. et al. Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity. Neuron 41, 625-638 (2004). Using gene-expression profiling and PSD-95-deficient mice, this paper implicates changes in the level of PSD-95 in psychostimulant action and addiction to drugs of abuse.
-
(2004)
Neuron
, vol.41
, pp. 625-638
-
-
Yao, W.D.1
-
67
-
-
0033103971
-
Synaptic targeting of the postsynaptic density protein PSD-95 mediated by lipid and protein motifs
-
Craven, S. E., El-Husseini, A. E. & Bredt, D. S. Synaptic targeting of the postsynaptic density protein PSD-95 mediated by lipid and protein motifs. Neuron 22, 497-509 (1999).
-
(1999)
Neuron
, vol.22
, pp. 497-509
-
-
Craven, S.E.1
El-Husseini, A.E.2
Bredt, D.S.3
-
68
-
-
18344396972
-
Synaptic strength regulated by palmitate cycling on PSD-95
-
El-Husseini Ael, D. et al. Synaptic strength regulated by palmitate cycling on PSD-95. Cell 108, 849-863 (2002). This paper reports that palmitoylation and depalmitoylation of PSD-95 regulate the synaptic localization of PSD-95, and consequently of AMPARs, in an activity-dependent manner.
-
(2002)
Cell
, vol.108
, pp. 849-863
-
-
El-Husseini Ael, D.1
-
69
-
-
0345119031
-
Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression
-
Colledge, M. et al. Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression. Neuron 40, 595-607 (2003). The authors provide evidence that synaptic activity rapidly breaks down PSD-95 via the ubiquitin-proteasome pathway and that this degradation is required for activity-induced internalization of synaptic AMPARs.
-
(2003)
Neuron
, vol.40
, pp. 595-607
-
-
Colledge, M.1
-
70
-
-
0742270492
-
Cyclin-dependent kinase 5 phosphorylates the N-terminal domain of the postsynaptic density protein PSD-95 in neurons
-
Morabito, M. A., Sheng, M. & Tsai, L. H. Cyclin-dependent kinase 5 phosphorylates the N-terminal domain of the postsynaptic density protein PSD-95 in neurons. J. Neurosci. 24, 865-876 (2004).
-
(2004)
J. Neurosci.
, vol.24
, pp. 865-876
-
-
Morabito, M.A.1
Sheng, M.2
Tsai, L.H.3
-
71
-
-
3242672694
-
CaMKII-dependent phosphorylation drives synapse-associated protein 97 into spines
-
Mauceri, D., Cattabeni, F., Di Luca, M. & Gardoni, F. CaMKII-dependent phosphorylation drives synapse-associated protein 97 into spines. J. Biol. Chem. 279, 23813-23821 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 23813-23821
-
-
Mauceri, D.1
Cattabeni, F.2
Di Luca, M.3
Gardoni, F.4
-
72
-
-
0033529567
-
Regulation of DLG localization at synapses by CaMKII-dependent phosphorylation
-
Koh, Y. H., Popova, E., Thomas, U., Griffith, L. C. & Budnik, V. Regulation of DLG localization at synapses by CaMKII-dependent phosphorylation. Cell 98, 353-363 (1999).
-
(1999)
Cell
, vol.98
, pp. 353-363
-
-
Koh, Y.H.1
Popova, E.2
Thomas, U.3
Griffith, L.C.4
Budnik, V.5
-
73
-
-
0038383463
-
The dynamic organization of postsynaptic proteins: Translocating molecules regulate synaptic function
-
Inoue, A. & Okabe, S. The dynamic organization of postsynaptic proteins: translocating molecules regulate synaptic function. Curr. Opin. Neurobiol. 13, 332-340 (2003).
-
(2003)
Curr. Opin. Neurobiol.
, vol.13
, pp. 332-340
-
-
Inoue, A.1
Okabe, S.2
-
74
-
-
0037418328
-
Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate receptor 2A signaling
-
Fagiolini, M. et al. Separable features of visual cortical plasticity revealed by N-methyl-D-aspartate receptor 2A signaling. Proc. Natl Acad. Sci. USA 100, 2854-2859 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 2854-2859
-
-
Fagiolini, M.1
-
75
-
-
0042626165
-
Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein
-
Tao, Y. X. et al. Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein. J. Neurosci. 23, 6703-6712 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 6703-6712
-
-
Tao, Y.X.1
-
76
-
-
0037844855
-
PDZ-containing proteins provide a functional postsynaptic scaffold for nicotinic receptors in neurons
-
Conroy, W. G., Liu, Z., Nai, Q., Coggan, J. S. & Berg, D. K. PDZ-containing proteins provide a functional postsynaptic scaffold for nicotinic receptors in neurons. Neuron 38, 759-771 (2003).
-
(2003)
Neuron
, vol.38
, pp. 759-771
-
-
Conroy, W.G.1
Liu, Z.2
Nai, Q.3
Coggan, J.S.4
Berg, D.K.5
-
77
-
-
1642275887
-
PSD93 regulates synaptic stability at neuronal cholinergic synapses
-
Parker, M. J., Zhao, S., Bredt, D. S., Sanes, J. R. & Feng, G. PSD93 regulates synaptic stability at neuronal cholinergic synapses. J. Neurosci. 24, 378-388 (2004). References 76 and 77 identify PSD-93 as being important for the structure and functions of neuronal cholinergic synapses, in addition to glutamatergic synapses.
-
(2004)
J. Neurosci.
, vol.24
, pp. 378-388
-
-
Parker, M.J.1
Zhao, S.2
Bredt, D.S.3
Sanes, J.R.4
Feng, G.5
-
78
-
-
0034604696
-
Ion channel clustering by membrane-associated guanylate kinases. Differential regulation by N-terminal lipid and metal binding motifs
-
El-Husseini, A. E. et al. Ion channel clustering by membrane-associated guanylate kinases. Differential regulation by N-terminal lipid and metal binding motifs. J. Biol. Chem. 275, 23904-23910 (2000).
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23904-23910
-
-
El-Husseini, A.E.1
-
79
-
-
0033792684
-
SAP97 concentrates at the postsynaptic density in cerebral cortex
-
Valtschanoff, J. G. et al. SAP97 concentrates at the postsynaptic density in cerebral cortex. Eur. J. Neurosci. 12, 3605-3614 (2000).
-
(2000)
Eur. J. Neurosci.
, vol.12
, pp. 3605-3614
-
-
Valtschanoff, J.G.1
-
80
-
-
0035478061
-
Synapse-associated protein 97 selectively associates with a subset of AMPA receptors early in their biosynthetic pathway
-
Sans, N. et al. Synapse-associated protein 97 selectively associates with a subset of AMPA receptors early in their biosynthetic pathway. J. Neurosci. 21, 7506-7516 (2001).
-
(2001)
J. Neurosci.
, vol.21
, pp. 7506-7516
-
-
Sans, N.1
-
81
-
-
0038794104
-
Synapse-associated protein-97 isoform-specific regulation of surface AMPA receptors and synaptic function in cultured neurons
-
Rumbaugh, G., Sia, G. M., Garner, C. C. & Huganir, R. L. Synapse-associated protein-97 isoform-specific regulation of surface AMPA receptors and synaptic function in cultured neurons. J. Neurosci. 23, 4567-4576 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 4567-4576
-
-
Rumbaugh, G.1
Sia, G.M.2
Garner, C.C.3
Huganir, R.L.4
-
82
-
-
0034143323
-
A developmental change in NMDA receptor-associated proteins at hippocampal synapses
-
Sans, N. et al. A developmental change in NMDA receptor-associated proteins at hippocampal synapses. J. Neurosci. 20, 1260-1271 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 1260-1271
-
-
Sans, N.1
-
83
-
-
0037417988
-
Developmental loss of miniature N-methyl-D-aspartate receptor currents in NR2A knockout mice
-
Townsend, M., Yoshii, A., Mishina, M. & Constantine-Paton, M. Developmental loss of miniature N-methyl-D-aspartate receptor currents in NR2A knockout mice. Proc. Natl Acad. Sci. USA 100, 1340-1345 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1340-1345
-
-
Townsend, M.1
Yoshii, A.2
Mishina, M.3
Constantine-Paton, M.4
-
84
-
-
0037385008
-
PSD-95 regulates NMDA receptors in developing cerebellar granule neurons of the rat
-
Losi, G. et al. PSD-95 regulates NMDA receptors in developing cerebellar granule neurons of the rat. J. Physiol. 548, 21-29 (2003).
-
(2003)
J. Physiol.
, vol.548
, pp. 21-29
-
-
Losi, G.1
-
85
-
-
0742298944
-
Interaction of transmembrane AMPA receptor regulatory proteins with multiple membrane associated guanylate kinases
-
Dakoji, S., Tomita, S., Karimzadegan, S., Nicoll, R. A. & Bredt, D. S. Interaction of transmembrane AMPA receptor regulatory proteins with multiple membrane associated guanylate kinases. Neuropharmacology 45, 849-856 (2003).
-
(2003)
Neuropharmacology
, vol.45
, pp. 849-856
-
-
Dakoji, S.1
Tomita, S.2
Karimzadegan, S.3
Nicoll, R.A.4
Bredt, D.S.5
-
86
-
-
0032584656
-
SAP97 is associated with the α-amino-3-hydroxy-5-methylisoxazole-4- propionic acid receptor GluR1 subunit
-
Leonard, A. S., Davare, M. A., Home, M. C., Garner, C. C. & Hell, J. W. SAP97 is associated with the α-amino-3-hydroxy-5-methylisoxazole-4- propionic acid receptor GluR1 subunit. J. Biol. Chem. 273, 19518-19524 (1998).
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 19518-19524
-
-
Leonard, A.S.1
Davare, M.A.2
Home, M.C.3
Garner, C.C.4
Hell, J.W.5
-
87
-
-
0141918783
-
AMPA receptor trafficking at excitatory synapses
-
Bredt, D. S. & Nicoll, R. A. AMPA receptor trafficking at excitatory synapses. Neuron 40, 361-379 (2003).
-
(2003)
Neuron
, vol.40
, pp. 361-379
-
-
Bredt, D.S.1
Nicoll, R.A.2
-
88
-
-
0036305484
-
AMPA receptor trafficking and synaptic plasticity
-
Malinow, R. & Malenka, R. C. AMPA receptor trafficking and synaptic plasticity. Annu. Rev. Neurosci. 25, 103-126 (2002).
-
(2002)
Annu. Rev. Neurosci.
, vol.25
, pp. 103-126
-
-
Malinow, R.1
Malenka, R.C.2
-
89
-
-
0242407128
-
Tandem PDZ repeats in glutamate receptor-interacting proteins have a novel mode of PDZ domain-mediated target binding
-
Feng, W., Shi, Y., Li, M. & Zhang, M. Tandem PDZ repeats in glutamate receptor-interacting proteins have a novel mode of PDZ domain-mediated target binding. Nature Struct. Biol. 10, 972-978 (2003).
-
(2003)
Nature Struct. Biol.
, vol.10
, pp. 972-978
-
-
Feng, W.1
Shi, Y.2
Li, M.3
Zhang, M.4
-
90
-
-
0033103887
-
EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains
-
Bruckner, K. et al. EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains. Neuron 22, 511-524 (1999).
-
(1999)
Neuron
, vol.22
, pp. 511-524
-
-
Bruckner, K.1
-
91
-
-
0033679909
-
GRASP-1: A neuronal RasGEF associated with the AMPA receptor/GRIP complex
-
Ye, B. et al. GRASP-1: a neuronal RasGEF associated with the AMPA receptor/GRIP complex. Neuron 26, 603-617 (2000).
-
(2000)
Neuron
, vol.26
, pp. 603-617
-
-
Ye, B.1
-
92
-
-
0037187640
-
Interaction between GRIP and liprin-a/SYD2 required for AMPA receptor targeting
-
Wyszynski, M. et al. Interaction between GRIP and liprin-a/SYD2 required for AMPA receptor targeting. Neuron 34, 39-52 (2002).
-
(2002)
Neuron
, vol.34
, pp. 39-52
-
-
Wyszynski, M.1
-
93
-
-
0842310833
-
A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1
-
Takamiya, K. et al. A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1. Nature Genet. 36, 172-177 (2004).
-
(2004)
Nature Genet.
, vol.36
, pp. 172-177
-
-
Takamiya, K.1
-
94
-
-
0037456522
-
Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP
-
Hirbec, H. et al. Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP. Neuron 37, 625-638 (2003).
-
(2003)
Neuron
, vol.37
, pp. 625-638
-
-
Hirbec, H.1
-
95
-
-
0037076403
-
Epidermolysis bullosa and embryonic lethality in mice lacking the multi-PDZ domain protein GRIP1
-
Bladt, F., Tafuri, A., Gelkop, S., Langille, L. & Pawson, T. Epidermolysis bullosa and embryonic lethality in mice lacking the multi-PDZ domain protein GRIP1. Proc. Natl Acad. Sci. USA 99, 6816-6821 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 6816-6821
-
-
Bladt, F.1
Tafuri, A.2
Gelkop, S.3
Langille, L.4
Pawson, T.5
-
96
-
-
0036584774
-
Differential palmitoylation directs the AMPA receptor-binding protein ABP to spines or to intracellular clusters
-
DeSouza, S., Fu, J., States, B. A. & Ziff, E. B. Differential palmitoylation directs the AMPA receptor-binding protein ABP to spines or to intracellular clusters. J. Neurosci. 22, 3493-3503 (2002).
-
(2002)
J. Neurosci.
, vol.22
, pp. 3493-3503
-
-
DeSouza, S.1
Fu, J.2
States, B.A.3
Ziff, E.B.4
-
97
-
-
0042422070
-
Intracellular membrane targeting and suppression of Ser880 phosphorylation of glutamate receptor 2 by the linker I-set II domain of AMPA receptor-binding protein
-
Fu, J., deSouza, S. & Ziff, E. B. Intracellular membrane targeting and suppression of Ser880 phosphorylation of glutamate receptor 2 by the linker I-set II domain of AMPA receptor-binding protein. J. Neurosci. 23, 7592-7601 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 7592-7601
-
-
Fu, J.1
DeSouza, S.2
Ziff, E.B.3
-
98
-
-
0033178981
-
Association of AMPA receptors with a subset of glutamate receptor-interacting protein in vivo
-
Wyszynski, M. et al. Association of AMPA receptors with a subset of glutamate receptor-interacting protein in vivo. J. Neurosci. 19, 6528-6537 (1999).
-
(1999)
J. Neurosci.
, vol.19
, pp. 6528-6537
-
-
Wyszynski, M.1
-
99
-
-
0037036109
-
Trans-synaptic Eph receptor-ephrin signaling in hippocampal mossy fiber LTP
-
Contractor, A. et al. Trans-synaptic Eph receptor-ephrin signaling in hippocampal mossy fiber LTP. Science 296, 1864-1869 (2002). This paper shows that the PDZ interaction of EphB receptors with GRIP and trans-synaptic interactions between B-ephrins and EphB receptors are important for the induction of mossy fibre LTP in the CA3 area of the hippocampus.
-
(2002)
Science
, vol.296
, pp. 1864-1869
-
-
Contractor, A.1
-
100
-
-
0346732915
-
Hippocampal plasticity requires postsynaptic ephrinBs
-
Grunwald, I. C. et al. Hippocampal plasticity requires postsynaptic ephrinBs. Nature Neurosci. 7, 33-40 (2004).
-
(2004)
Nature Neurosci.
, vol.7
, pp. 33-40
-
-
Grunwald, I.C.1
-
101
-
-
0346218115
-
Surface expression of the netrin receptor UNC5H1 is regulated through a protein kinase C-interacting protein/protein kinase-dependent mechanism
-
Williams, M. E., Wu, S. C., McKenna, W. L. & Hinck, L. Surface expression of the netrin receptor UNC5H1 is regulated through a protein kinase C-interacting protein/protein kinase-dependent mechanism. J. Neurosci. 23, 11279-11288 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 11279-11288
-
-
Williams, M.E.1
Wu, S.C.2
McKenna, W.L.3
Hinck, L.4
-
102
-
-
0037124377
-
PICK1 is required for the control of synaptic transmission by the metabotropic glutamate receptor 7
-
Perroy, J. et al. PICK1 is required for the control of synaptic transmission by the metabotropic glutamate receptor 7. EMBO J. 21, 2990-2999 (2002).
-
(2002)
EMBO J.
, vol.21
, pp. 2990-2999
-
-
Perroy, J.1
-
103
-
-
0037013318
-
The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs
-
Hirbec, H. et al. The PDZ proteins PICK1, GRIP, and syntenin bind multiple glutamate receptor subtypes. Analysis of PDZ binding motifs. J. Biol. Chem. 277, 15221-15224 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 15221-15224
-
-
Hirbec, H.1
-
104
-
-
0035026044
-
Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1
-
Torres, G. E. et al. Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1. Neuron 30, 121-134 (2001).
-
(2001)
Neuron
, vol.30
, pp. 121-134
-
-
Torres, G.E.1
-
105
-
-
0035805585
-
The ERBB2/HER2 receptor deferentially interacts with ERBIN and PICK1 PSD-95/DLG/ZO-1 domain proteins
-
Jaulin-Bastard, F. et al. The ERBB2/HER2 receptor deferentially interacts with ERBIN and PICK1 PSD-95/DLG/ZO-1 domain proteins. J. Biol. Chem. 276, 15256-15263 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 15256-15263
-
-
Jaulin-Bastard, F.1
-
106
-
-
0037076287
-
Differential roles for NSF and GRIP/ABP in AMPA receptor cycling
-
Braithwaite, S. P., Xia, H. & Malenka, R. C. Differential roles for NSF and GRIP/ABP in AMPA receptor cycling. Proc. Natl Acad. Sci. USA 99, 7096-7101 (2002).
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 7096-7101
-
-
Braithwaite, S.P.1
Xia, H.2
Malenka, R.C.3
-
107
-
-
0038518145
-
Requirement of AMPA receptor GluR2 phosphorylation for cerebellar long-term depression
-
Chung, H. J., Steinberg, J. P., Huganir, R. L. & Linden, D. J. Requirement of AMPA receptor GluR2 phosphorylation for cerebellar long-term depression. Science 300, 1751-1755 (2003). By rescue experiments in GluR2-deficient Purkinje cell cultures, the authors show that phosphorylation of Ser880 in GLUR2 is required for the induction of cerebellar LTD.
-
(2003)
Science
, vol.300
, pp. 1751-1755
-
-
Chung, H.J.1
Steinberg, J.P.2
Huganir, R.L.3
Linden, D.J.4
-
108
-
-
0034523581
-
PDZ proteins interacting with C-terminal GluR2/3 are invoked in a PKC-dependent regulation of AMPA receptors at hippocampal synapses
-
Daw, M. I. et al. PDZ proteins interacting with C-terminal GluR2/3 are invoked in a PKC-dependent regulation of AMPA receptors at hippocampal synapses. Neuron 28, 873-886 (2000).
-
(2000)
Neuron
, vol.28
, pp. 873-886
-
-
Daw, M.I.1
-
109
-
-
0035949629
-
Interaction of the AMPA receptor subunit GluR2/3 with PDZ domains regulates hippocampal long-term depression
-
Kim, C. H., Chung, H. J., Lee, H. K. & Huganir, R. L. Interaction of the AMPA receptor subunit GluR2/3 with PDZ domains regulates hippocampal long-term depression. Proc. Natl Acad. Sci. USA 98, 11725-11730 (2001).
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 11725-11730
-
-
Kim, C.H.1
Chung, H.J.2
Lee, H.K.3
Huganir, R.L.4
-
110
-
-
0141919571
-
Glutamate receptor subunit 2 Serine 880 phosphorylation modulates synaptic transmission and mediates plasticity in CA1 pyramidal cells
-
Seidenman, K. J., Steinberg, J. P., Huganir, R. & Malinow, R. Glutamate receptor subunit 2 Serine 880 phosphorylation modulates synaptic transmission and mediates plasticity in CA1 pyramidal cells. J. Neurosci. 23, 9220-9228 (2003).
-
(2003)
J. Neurosci.
, vol.23
, pp. 9220-9228
-
-
Seidenman, K.J.1
Steinberg, J.P.2
Huganir, R.3
Malinow, R.4
-
111
-
-
0036662882
-
Association of the kinesin superfamily motor protein KIF1Bα with postsynaptic density-95 (PSD-95), synapse-associated protein-97, and synaptic scaffolding molecule PSD-95/discs large/zona occludens-1 proteins
-
Mok, H. et al. Association of the kinesin superfamily motor protein KIF1Bα with postsynaptic density-95 (PSD-95), synapse-associated protein-97, and synaptic scaffolding molecule PSD-95/discs large/zona occludens-1 proteins. J. Neurosci. 22, 5253-5258 (2002).
-
(2002)
J. Neurosci.
, vol.22
, pp. 5253-5258
-
-
Mok, H.1
-
112
-
-
0037424398
-
Direct interaction with a kinesin-related motor mediates transport of mammalian discs large tumor suppressor homologue in epithelial cells
-
Asaba, N., Hanada, T., Takeuchi, A. & Chishti, A. H. Direct interaction with a kinesin-related motor mediates transport of mammalian discs large tumor suppressor homologue in epithelial cells. J. Biol. Chem. 278, 8395-8400 (2002).
-
(2002)
J. Biol. Chem.
, vol.278
, pp. 8395-8400
-
-
Asaba, N.1
Hanada, T.2
Takeuchi, A.3
Chishti, A.H.4
-
113
-
-
0037163078
-
Interaction of SAP97 with minus-end-directed actin motor myosin VI. Implications for AMPA receptor trafficking
-
Wu, H., Nash, J. E., Zamorano, P. & Garner, C. C. Interaction of SAP97 with minus-end-directed actin motor myosin VI. Implications for AMPA receptor trafficking. J. Biol. Chem. 277, 30928-30934 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 30928-30934
-
-
Wu, H.1
Nash, J.E.2
Zamorano, P.3
Garner, C.C.4
-
114
-
-
0034660288
-
Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein
-
Naisbitt, S. et al. Interaction of the postsynaptic density-95/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein. J. Neurosci. 20, 4524-4534 (2000).
-
(2000)
J. Neurosci.
, vol.20
, pp. 4524-4534
-
-
Naisbitt, S.1
-
115
-
-
0038713372
-
NMDA receptor trafficking through an interaction between PDZ proteins and the exocyst complex
-
Sans, N. et al. NMDA receptor trafficking through an interaction between PDZ proteins and the exocyst complex. Nature Cell Biol. 5, 520-530 (2003). This paper reports that SecB, a component of the exocyst complex, associates with SAP102, a member of the PSD-95 family, and regulates the surface expression and synaptic localization of the NMDARs.
-
(2003)
Nature Cell Biol.
, vol.5
, pp. 520-530
-
-
Sans, N.1
-
116
-
-
0032544565
-
The LIN-2/LIN-7/LIN-10 complex mediates basolateral membrane localization of the C. elegans EGF receptor LET-23 in vulval epithelial cells
-
Kaech, S. M., Whitfield, C. W. & Kim, S. K. The LIN-2/LIN-7/LIN-10 complex mediates basolateral membrane localization of the C. elegans EGF receptor LET-23 in vulval epithelial cells. Cell 94, 761-771 (1998).
-
(1998)
Cell
, vol.94
, pp. 761-771
-
-
Kaech, S.M.1
Whitfield, C.W.2
Kim, S.K.3
-
117
-
-
0032544612
-
LIN-10 is a shared component of the polarized protein localization pathways in neurons and epithelia
-
Rongo, C., Whitfield, C. W., Rodal, A., Kim, S. K. & Kaplan, J. M. LIN-10 is a shared component of the polarized protein localization pathways in neurons and epithelia. Cell 94, 751-759 (1998).
-
(1998)
Cell
, vol.94
, pp. 751-759
-
-
Rongo, C.1
Whitfield, C.W.2
Rodal, A.3
Kim, S.K.4
Kaplan, J.M.5
-
118
-
-
0034625631
-
Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport
-
Setou, M., Nakagawa, T., Seog, D. H. & Hirokawa, N. Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport. Science 288, 1796-1802 (2000). The KIF17 kinesin motor is shown to interact with the PDZ1 domain of LIN10 and to transport the LIN2/LIN7/LIN10/ NMDAR complex to synapses, suggesting that PDZ proteins can function as receptors that link motors to their specific cargoes.
-
(2000)
Science
, vol.288
, pp. 1796-1802
-
-
Setou, M.1
Nakagawa, T.2
Seog, D.H.3
Hirokawa, N.4
-
119
-
-
0037417897
-
A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission
-
Ho, A., Morishita, W., Hammer, R. E., Malenka, R. C. & Sudhof, T. C. A role for Mints in transmitter release: Mint 1 knockout mice exhibit impaired GABAergic synaptic transmission. Proc. Natl Acad. Sci. USA 100, 1409-1414 (2003).
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1409-1414
-
-
Ho, A.1
Morishita, W.2
Hammer, R.E.3
Malenka, R.C.4
Sudhof, T.C.5
-
120
-
-
0034673760
-
Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2
-
Hsueh, Y. P., Wang, T. F., Yang, F. C. & Sheng, M. Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2. Nature 404, 298-302 (2000).
-
(2000)
Nature
, vol.404
, pp. 298-302
-
-
Hsueh, Y.P.1
Wang, T.F.2
Yang, F.C.3
Sheng, M.4
-
121
-
-
11144354900
-
Transcriptional modification by a CASK-interacting nucleosome assembly protein
-
Wang, G. S. et al. Transcriptional modification by a CASK-interacting nucleosome assembly protein. Neuron 42, 113-128 (2004).
-
(2004)
Neuron
, vol.42
, pp. 113-128
-
-
Wang, G.S.1
-
122
-
-
0037007668
-
Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites
-
Setou, M. et al. Glutamate-receptor-interacting protein GRIP1 directly steers kinesin to dendrites. Nature 417, 83-87 (2002).
-
(2002)
Nature
, vol.417
, pp. 83-87
-
-
Setou, M.1
-
123
-
-
0038176515
-
Association of the kinesin motor KIF1A with the multimodular protein liprin-α
-
Shin, H. et al. Association of the kinesin motor KIF1A with the multimodular protein liprin-α. J. Biol. Chem. 278, 11393-11401 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 11393-11401
-
-
Shin, H.1
-
124
-
-
0037171756
-
PSD-95 mediates formation of a functional homomeric Kir5.1 channel in the brain
-
Tanemoto, M., Fujita, A., Higashi, K. & Kurachi, Y. PSD-95 mediates formation of a functional homomeric Kir5.1 channel in the brain. Neuron 34, 387-397 (2002).
-
(2002)
Neuron
, vol.34
, pp. 387-397
-
-
Tanemoto, M.1
Fujita, A.2
Higashi, K.3
Kurachi, Y.4
-
125
-
-
0037059786
-
G protein-coupled receptor kinase 5 regulates β1-adrenergic receptor association with PSD-95
-
Hu, L. A., Chen, W., Premont, R. T., Cong, M. & Lefkowitz, R. J. G protein-coupled receptor kinase 5 regulates β1-adrenergic receptor association with PSD-95. J. Biol. Chem. 277, 1607-1613 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1607-1613
-
-
Hu, L.A.1
Chen, W.2
Premont, R.T.3
Cong, M.4
Lefkowitz, R.J.5
-
126
-
-
0037023742
-
Phosphorylation of stargazin by protein kinase A regulates its interaction win PSD-95
-
Choi, J. et al. Phosphorylation of stargazin by protein kinase A regulates its interaction win PSD-95. J. Biol. Chem. 277, 12359-12363 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 12359-12363
-
-
Choi, J.1
-
127
-
-
0037101605
-
Phosphorylation of the postsynaptic density-95 (PSD-95)/discs large/zona occludens-1 binding site of stargazin regulates binding to PSD-95 and synaptic targeting of AMPA receptors
-
Chetkovich, D. M., Chen, L., Stocker, T. J., Nicoll, R. A. & Bredt, D. S. Phosphorylation of the postsynaptic density-95 (PSD-95)/discs large/zona occludens-1 binding site of stargazin regulates binding to PSD-95 and synaptic targeting of AMPA receptors. J. Neurosci. 22, 5791-5796 (2002).
-
(2002)
J. Neurosci.
, vol.22
, pp. 5791-5796
-
-
Chetkovich, D.M.1
Chen, L.2
Stocker, T.J.3
Nicoll, R.A.4
Bredt, D.S.5
-
128
-
-
0035425710
-
PICK1 targets activated protein kinase Cα to AMPA receptor clusters in spines of hippocampal neurons and reduces surface levels of the AMPA-type glutamate receptor subunit 2
-
Perez, J. L. et al. PICK1 targets activated protein kinase Cα to AMPA receptor clusters in spines of hippocampal neurons and reduces surface levels of the AMPA-type glutamate receptor subunit 2. J. Neurosci. 21, 5417-5428 (2001).
-
(2001)
J. Neurosci.
, vol.21
, pp. 5417-5428
-
-
Perez, J.L.1
-
129
-
-
0038143615
-
The NMDA receptor complex is altered in an animal model of human cerebral heterotopia
-
Gardoni, F. et al. The NMDA receptor complex is altered in an animal model of human cerebral heterotopia. J. Neuropathol. Exp. Neurol. 62, 662-675 (2003).
-
(2003)
J. Neuropathol. Exp. Neurol.
, vol.62
, pp. 662-675
-
-
Gardoni, F.1
-
130
-
-
0030604722
-
Crystal structures of a complexed and peptide-free membrane protein-binding domain: Molecular basis of peptide recognition by PDZ
-
Doyle, D. A. et al. Crystal structures of a complexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by PDZ. Cell 85, 1067-1076 (1996).
-
(1996)
Cell
, vol.85
, pp. 1067-1076
-
-
Doyle, D.A.1
-
131
-
-
0029098659
-
Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95
-
Komau, H. C., Schenker, L. T., Kennedy, M. B. & Seeburg, P. H. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science 269, 1737-1740 (1995).
-
(1995)
Science
, vol.269
, pp. 1737-1740
-
-
Komau, H.C.1
Schenker, L.T.2
Kennedy, M.B.3
Seeburg, P.H.4
-
132
-
-
0032191152
-
SAP90 binds and clusters kainate receptors causing incomplete desensitization
-
Garcia, E. P. et al. SAP90 binds and clusters kainate receptors causing incomplete desensitization. Neuron 21, 727-739 (1998).
-
(1998)
Neuron
, vol.21
, pp. 727-739
-
-
Garcia, E.P.1
-
133
-
-
0033562433
-
Postsynaptic density-93 interacts with the 62 glutamate receptor subunit at parallel fiber synapses
-
Roche, K. W. et al. Postsynaptic density-93 interacts with the 62 glutamate receptor subunit at parallel fiber synapses. J. Neurosci. 19, 3926-3934 (1999).
-
(1999)
J. Neurosci.
, vol.19
, pp. 3926-3934
-
-
Roche, K.W.1
-
134
-
-
2442626585
-
The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins
-
Becamel, C. et al. The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins. J. Biol. Chem. 279, 20257-20266 (2004).
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20257-20266
-
-
Becamel, C.1
-
135
-
-
0034724391
-
The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses
-
Garcia, R. A., Vasudevan, K. & Buonanno, A. The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses. Proc. Natl Acad. Sci. USA 97, 3596-3601 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 3596-3601
-
-
Garcia, R.A.1
Vasudevan, K.2
Buonanno, A.3
-
136
-
-
0033697710
-
Regulation of neuregulin signaling by PSD-95 interacting with ErbB4 at CNS synapses
-
Huang, Y. Z. et al. Regulation of neuregulin signaling by PSD-95 interacting with ErbB4 at CNS synapses. Neuron 26, 443-455 (2000).
-
(2000)
Neuron
, vol.26
, pp. 443-455
-
-
Huang, Y.Z.1
-
137
-
-
1642499478
-
Cypin regulates dendrite patterning in hippocampal neurons by promoting microtubule assembly
-
Akum, B. F. et al. Cypin regulates dendrite patterning in hippocampal neurons by promoting microtubule assembly. Nature Neurosci. 7, 145-152 (2004).
-
(2004)
Nature Neurosci.
, vol.7
, pp. 145-152
-
-
Akum, B.F.1
-
138
-
-
0037561152
-
Interaction of the tyrosine kinase Pyk2 with the N-methyl-D-aspartate receptor complex via the Src homology 3 domains of PSD-95 and SAP102
-
Seabold, G. K., Burette, A., Lim, I. A., Weinberg, R. J. & Hell, J. W. Interaction of the tyrosine kinase Pyk2 with the N-methyl-D-aspartate receptor complex via the Src homology 3 domains of PSD-95 and SAP102. J. Biol. Chem. 278, 15040-15048 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 15040-15048
-
-
Seabold, G.K.1
Burette, A.2
Lim, I.A.3
Weinberg, R.J.4
Hell, J.W.5
-
139
-
-
0031052970
-
GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP 90 family of channel clustering molecules
-
Kim, E. et al. GKAP, a novel synaptic protein that interacts with the guanylate kinase-like domain of the PSD-95/SAP90 family of channel clustering molecules. J. Cell. Biol. 136, 669-678 (1997).
-
(1997)
J. Cell. Biol.
, vol.136
, pp. 669-678
-
-
Kim, E.1
-
140
-
-
0036703649
-
Postsynaptic targeting of alternative postsynaptic density-95 isoforms by distinct mechanisms
-
Chetkovich, D. M. et al. Postsynaptic targeting of alternative postsynaptic density-95 isoforms by distinct mechanisms. J. Neurosci. 22, 6415-6425 (2002).
-
(2002)
J. Neurosci.
, vol.22
, pp. 6415-6425
-
-
Chetkovich, D.M.1
-
141
-
-
0036179747
-
A novel and conserved protein-protein interaction domain of mammalian Lin-2/CASK binds and recruits SAP97 to the lateral surface of epithelia
-
Lee, S., Fan, S., Makarova, O., Straight, S. & Margolis, B. A novel and conserved protein-protein interaction domain of mammalian Lin-2/CASK binds and recruits SAP97 to the lateral surface of epithelia. Mol. Cell Biol. 22, 1778-1791 (2002).
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 1778-1791
-
-
Lee, S.1
Fan, S.2
Makarova, O.3
Straight, S.4
Margolis, B.5
-
142
-
-
0034254991
-
Spinophilin regulates the formation and function of dendritic spines
-
Feng, J. et al. Spinophilin regulates the formation and function of dendritic spines. Proc. Natl Acad. Sci. USA 97, 9287-9292 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 9287-9292
-
-
Feng, J.1
-
143
-
-
0037232646
-
Nectin and afadin: Novel organizers of intercellular junctions
-
Takai, Y. & Nakanishi, H. Nectin and afadin: novel organizers of intercellular junctions. J. Cell Sci. 116, 17-27 (2003).
-
(2003)
J. Cell Sci.
, vol.116
, pp. 17-27
-
-
Takai, Y.1
Nakanishi, H.2
-
144
-
-
0035863159
-
2+/calmodulin-dependent protein kinase II and α-actinin
-
2+/calmodulin-dependent protein kinase II and α-actinin. J. Neurosci. 21, 423-433 (2001).
-
(2001)
J. Neurosci.
, vol.21
, pp. 423-433
-
-
Wallkonis, R.S.1
-
145
-
-
18744419607
-
Erbin: Sorting out ErbB2 receptors or giving Ras a break?
-
Kolch, W. Erbin: sorting out ErbB2 receptors or giving Ras a break? Sci. STKE, pe37 (2003).
-
(2003)
Sci. STKE
-
-
Kolch, W.1
-
146
-
-
0034879863
-
Regulation of dendritic spine morphology and synaptic function by Shank and Homer
-
Sala, C. et al. Regulation of dendritic spine morphology and synaptic function by Shank and Homer. Neuron 31, 115-130 (2001).
-
(2001)
Neuron
, vol.31
, pp. 115-130
-
-
Sala, C.1
-
147
-
-
0038013863
-
Tamalin is a scaffold protein that interacts with multiple neuronal proteins in distinct modes of protein-protein association
-
Kitano, J. et al. Tamalin is a scaffold protein that interacts with multiple neuronal proteins in distinct modes of protein-protein association. J. Biol. Chem. 278, 14762-14768 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 14762-14768
-
-
Kitano, J.1
|