Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein-protein recognition: Application to the Bim BH3 domain

Protein Science

Volumn 17, Issue 7, 2008, Pages 1232-1240

  Boersma, Melissa D ^a   Sadowsky, Jack D ^a   Tomita, York A ^b   Gellman, Samuel H ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b GEORGETOWN UNIVERSITY   (United States)

Author keywords

Apoptosis; Bcl xL; Bim; Hydrophile scan; Mcl 1; Peptide

Indexed keywords

ALANINE; BH3 PROTEIN; BIM PROTEIN; GLUTAMIC ACID; LYSINE; POLYPEPTIDE; PROTEIN BCL XL; PROTEIN MCL 1;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; BINDING AFFINITY; HUMAN; HYDROPHILICITY; MOLECULAR RECOGNITION; MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN ENGINEERING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY;

ALANINE; APOPTOSIS REGULATORY PROTEINS; CIRCULAR DICHROISM; FLUORESCENCE POLARIZATION; MEMBRANE PROTEINS; MUTATION; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS;

EID: 46449115491     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1110/ps.032896.107     Document Type: Article

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