Synthetic α-helix mimetics as agonists and antagonists of islet amyloid polypeptide aggregation

Angewandte Chemie - International Edition

Volumn 49, Issue 4, 2010, Pages 736-739

  Saraogi, Ishu ^a   Hebda, James A ^a   Becerril, Jorge ^a   Estroff, Lara A ^a   Miranker, Andrew D ^a   Hamilton, Andrew D ^a  

^a YALE UNIVERSITY   (United States)

Author keywords

helix mimetics; Amyloid peptides; Diabetes; Helical structures; Proteomimetics

Indexed keywords

AMYLOID FORMATION; HELICAL MOTIFS; HELICAL STRUCTURES; MIMETICS; PROTEOMIMETICS; TYPE II;

PEPTIDES;

GLYCOPROTEINS;

1,2 DIOLEOYL SN GLYCERO 3 PHOSPHOGLYCEROL; 1,2 OLEOYLPHOSPHATIDYLCHOLINE; 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOGLYCEROL; 1,2-OLEOYLPHOSPHATIDYLCHOLINE; AMIDE; AMYLIN; AMYLOID; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLGLYCEROL;

ARTICLE; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; DRUG POTENTIATION; HYDROGEN BOND; KINETICS; METABOLISM; PROTEIN BINDING; X RAY CRYSTALLOGRAPHY;

AMIDES; AMYLOID; CRYSTALLOGRAPHY, X-RAY; HYDROGEN BONDING; KINETICS; MOLECULAR CONFORMATION; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLGLYCEROLS; PROTEIN BINDING;

EID: 74849110603     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.200901694     Document Type: Article

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