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Volumn 127, Issue 42, 2005, Pages 14584-14585

A rapid library screen for tailoring β-peptide structure and function

Author keywords

[No Author keywords available]

Indexed keywords

BETA DECAPEPTIDE BETA 53-1; BETA PEPTIDE; ONCOPROTEIN; PEPTIDE DERIVATIVE; PEPTIDE LIBRARY; PROTEIN MDM2; UNCLASSIFIED DRUG;

EID: 27144443340     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja055050o     Document Type: Article
Times cited : (64)

References (22)
  • 4
    • 0000577984 scopus 로고    scopus 로고
    • One-bead-one-compound libraries have been used extensively for ligand discovery using α-peptides, peptidomimetics, and some classes of small molecules. For reviews, see: (a) Lam, K. S.; Lebl, M.; Krchnak, V. Chem. Rev. 1997, 97, 411-448.
    • (1997) Chem. Rev. , vol.97 , pp. 411-448
    • Lam, K.S.1    Lebl, M.2    Krchnak, V.3
  • 10
    • 27144542872 scopus 로고    scopus 로고
    • note
    • See the Supporting Information.
  • 18
    • 27144536998 scopus 로고    scopus 로고
    • note
    • BioBSA, BSA, or no protein resulted in no observable Qdots-SA605 fluorescence localized to the beads. See the Supporting information for details.
  • 20
    • 27144489877 scopus 로고    scopus 로고
    • note
    • Of 20 individual library beads selected at random and all subsequent beads picked as hits. 95% possessed a single major product in the expected mass range when analyzed by MALDI and MS/MS.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.