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Angewandte Chemie - International Edition

Volumn 52, Issue 46, 2013, Pages 12187-12191

Highly functionalized terpyridines as competitive inhibitors of AKAP-PKA interactions

(23) Schäfer, Gesa a Milic̈, Jelena a Eldahshan, Adeeb a Götz, Frank a Zühlke, Kerstin a Schillinger, Christian b Kreuchwig, Annika b Elkins, Jonathan M c Abdulazeez, Kamal R c Oder, Andreas a Moutty, Marie C a Masada, Nanako d Beerbaum, Monika b Schlegel, Brigitte b Niquet, Sylvia a Schmieder, Peter b Krause, Gerd b Vonkries, Jens Peter a Cooper, Dermot M F d Knapp, Stefan c more..

a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE (Germany)

b LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE (Germany)

c UNIVERSITY OF OXFORD (United Kingdom)

d UNIVERSITY OF CAMBRIDGE (United Kingdom)

e FREIE UNIVERSITÄT BERLIN (Germany)

Author keywords

AKAP; peptide mimetics; protein kinaseA; protein protein interactions; Suzuki coupling; terpyridines

Indexed keywords

AKAP; PEPTIDE MIMETICS; PROTEIN KINASE A; PROTEIN-PROTEIN INTERACTIONS; SUZUKI COUPLINGS; TERPYRIDINES;

CHEMICAL REACTIONS; CHEMISTRY;

PROTEINS;

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE ANCHORING PROTEIN; PROTEIN KINASE INHIBITOR; PYRIDINE DERIVATIVE;

ANTAGONISTS AND INHIBITORS; BINDING COMPETITION; BINDING SITE; CHEMISTRY; HEK293 CELL LINE; HUMAN; METABOLISM; MOLECULAR DOCKING; PROTEIN DOMAIN; PROTEIN TERTIARY STRUCTURE; SYNTHESIS;

A KINASE ANCHOR PROTEINS; BINDING SITES; BINDING, COMPETITIVE; CYCLIC AMP-DEPENDENT PROTEIN KINASES; HEK293 CELLS; HUMANS; MOLECULAR DOCKING SIMULATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN KINASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; PYRIDINES;

EID: 84887482737 PISSN: 14337851 EISSN: 15213773 Source Type: Journal
DOI: 10.1002/anie.201304686 Document Type: Article

Times cited : (45)

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