Consequences of isostructural main-chain modifications for the design of antimicrobial foldamers: Helical mimics of host-defense peptides based on a heterogeneous amide/urea backbone

Angewandte Chemie - International Edition

Volumn 49, Issue 2, 2010, Pages 333-336

  Claudon, Paul ^a   Violette, Aude ^a   Lamour, Karen ^a   Decossas, Marion ^a   Fournel, Sylvie ^a   Heurtault, Béatrice ^b   Godet, Julien ^b   Mély, Yves ^b   Jamart Grégoire, Brigitte ^c   Averlant Petit, Marie Christine ^c   Briand, Jean Paul ^a   Duportail, Guy ^b   Monteil, Henri ^b   Guichard, Gilles ^a,d  

^a INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b UNIVERSITÉ DE STRASBOURG   (France)

^c LAB DE CHIM PHYS MACROMOLECULAIRE   (France)

^d UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

Amphiphiles; Antimicrobial agents; Helical structures; Peptidomimetics; Structure activity relationships

Indexed keywords

ANTIMICROBIAL AGENTS; MICROORGANISMS; PEPTIDES; UREA;

CHEMICAL EQUATIONS; HELICAL STRUCTURES; HOST DEFENSE; ISOSTRUCTURAL; MAIN CHAINS; PEPTIDOMIMETICS; RECOGNITION PROPERTIES; STRUCTURE ACTIVITY RELATIONSHIPS;

AMPHIPHILES;

EID: 73349095395     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200905591     Document Type: Article

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