-
1
-
-
73949136827
-
Cardiovascular fitness is associated with cognition in young adulthood
-
Åberg MA, Pedersen NL, Torén K, Svartengren M, Bäckstrand B, Johnsson T et al (2009) Cardiovascular fitness is associated with cognition in young adulthood. Proc Natl Acad Sci 106:20906–20911.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 20906-20911
-
-
Åberg, M.A.1
Pedersen, N.L.2
Torén, K.3
Svartengren, M.4
Bäckstrand, B.5
Johnsson, T.6
-
2
-
-
18244384051
-
Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease
-
Adlard PA, Perreau VM, Pop V, Cotman CW (2005) Voluntary exercise decreases amyloid load in a transgenic model of Alzheimer's disease. J Neurosci 25:4217–4221.
-
(2005)
J Neurosci
, vol.25
, pp. 4217-4221
-
-
Adlard, P.A.1
Perreau, V.M.2
Pop, V.3
Cotman, C.W.4
-
3
-
-
80052198680
-
Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging
-
Ahlskog JE, Geda YE, Graff-Radford NR, Petersen RC (2011) Physical exercise as a preventive or disease-modifying treatment of dementia and brain aging. Mayo Clin Proc 86:876–884.
-
(2011)
Mayo Clin Proc
, vol.86
, pp. 876-884
-
-
Ahlskog, J.E.1
Geda, Y.E.2
Graff-Radford, N.R.3
Petersen, R.C.4
-
4
-
-
80052198680
-
-
(eds) (, Mayo Clinic Proceedings., Elsevier, New York
-
Ahlskog JE, Geda YE, Graff-Radford NR, Petersen RC (eds) (2011) Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging. Mayo Clinic Proceedings. Elsevier: New York.
-
(2011)
Physical Exercise as a Preventive or Disease-Modifying Treatment of Dementia and Brain Aging
-
-
Ahlskog, J.E.1
Geda, Y.E.2
Graff-Radford, N.R.3
Petersen, R.C.4
-
5
-
-
0033963704
-
Oxidative stress and gene regulation
-
Allen R, Tresini M (2000) Oxidative stress and gene regulation. Free Radic Biol Med 28:463–499.
-
(2000)
Free Radic Biol Med
, vol.28
, pp. 463-499
-
-
Allen, R.1
Tresini, M.2
-
6
-
-
77957256216
-
Phosphorylation of tau at Thr212, Thr231, and Ser262 combined causes neurodegeneration
-
Alonso AD, Di Clerico J, Li B, Corbo CP, Alaniz ME, Grundke-Iqbal I et al (2010) Phosphorylation of tau at Thr212, Thr231, and Ser262 combined causes neurodegeneration. J Biol Chem 285:30851–30860.
-
(2010)
J Biol Chem
, vol.285
, pp. 30851-30860
-
-
Alonso, A.D.1
Di Clerico, J.2
Li, B.3
Corbo, C.P.4
Alaniz, M.E.5
Grundke-Iqbal, I.6
-
7
-
-
84922975921
-
Cerebrospinal fluid levels of a 20–22 kDa NH2 fragment of human tau provide a novel neuronal injury biomarker in Alzheimer's disease and other dementias
-
Amadoro G, Corsetti V, Sancesario GM, Lubrano A, Melchiorri G, Bernardini S et al (2014) Cerebrospinal fluid levels of a 20–22 kDa NH2 fragment of human tau provide a novel neuronal injury biomarker in Alzheimer's disease and other dementias. J Alzheimer's Dis 42:211–226.
-
(2014)
J Alzheimer's Dis
, vol.42
, pp. 211-226
-
-
Amadoro, G.1
Corsetti, V.2
Sancesario, G.M.3
Lubrano, A.4
Melchiorri, G.5
Bernardini, S.6
-
8
-
-
77957563700
-
A NH2 tau fragment targets neuronal mitochondria at AD synapses: possible implications for neurodegeneration
-
Amadoro G, Corsetti V, Stringaro A, Colone M, D'Aguanno S, Meli G et al (2010) A NH2 tau fragment targets neuronal mitochondria at AD synapses: possible implications for neurodegeneration. J Alzheimer's Dis 21:445–470.
-
(2010)
J Alzheimer's Dis
, vol.21
, pp. 445-470
-
-
Amadoro, G.1
Corsetti, V.2
Stringaro, A.3
Colone, M.4
D'Aguanno, S.5
Meli, G.6
-
9
-
-
0742306778
-
Role of N-terminal tau domain integrity on the survival of cerebellar granule neurons
-
Amadoro G, Serafino A, Barbato C, Ciotti M, Sacco A, Calissano P et al (2004) Role of N-terminal tau domain integrity on the survival of cerebellar granule neurons. Cell Death Differ 11:217–230.
-
(2004)
Cell Death Differ
, vol.11
, pp. 217-230
-
-
Amadoro, G.1
Serafino, A.2
Barbato, C.3
Ciotti, M.4
Sacco, A.5
Calissano, P.6
-
10
-
-
0037437192
-
Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells
-
Anandatheerthavarada HK, Biswas G, Robin M-A, Avadhani NG (2003) Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells. J Cell Biol 161:41–54.
-
(2003)
J Cell Biol
, vol.161
, pp. 41-54
-
-
Anandatheerthavarada, H.K.1
Biswas, G.2
Robin, M.-A.3
Avadhani, N.G.4
-
11
-
-
73649098791
-
Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria
-
Area-Gomez E, de Groof AJ, Boldogh I, Bird TD, Gibson GE, Koehler CM et al (2009) Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria. Am J Pathol 175:1810–1816.
-
(2009)
Am J Pathol
, vol.175
, pp. 1810-1816
-
-
Area-Gomez, E.1
de Groof, A.J.2
Boldogh, I.3
Bird, T.D.4
Gibson, G.E.5
Koehler, C.M.6
-
12
-
-
52949119162
-
A peptide containing residues 26–44 of tau protein impairs mitochondrial oxidative phosphorylation acting at the level of the adenine nucleotide translocator
-
Atlante A, Amadoro G, Bobba A, De Bari L, Corsetti V, Pappalardo G et al (2008) A peptide containing residues 26–44 of tau protein impairs mitochondrial oxidative phosphorylation acting at the level of the adenine nucleotide translocator. Biochim Biophys Acta (BBA)-Bioenerg 1777:1289–1300.
-
(2008)
Biochim Biophys Acta (BBA)-Bioenerg
, vol.1777
, pp. 1289-1300
-
-
Atlante, A.1
Amadoro, G.2
Bobba, A.3
De Bari, L.4
Corsetti, V.5
Pappalardo, G.6
-
13
-
-
1642289188
-
Role of tau protein in both physiological and pathological conditions
-
Avila J, Lucas JJ, Perez M, Hernandez F (2004) Role of tau protein in both physiological and pathological conditions. Physiol Rev 84:361–384.
-
(2004)
Physiol Rev
, vol.84
, pp. 361-384
-
-
Avila, J.1
Lucas, J.J.2
Perez, M.3
Hernandez, F.4
-
14
-
-
79958041601
-
The SirT3 divining rod points to oxidative stress
-
Bell EL, Guarente L (2011) The SirT3 divining rod points to oxidative stress. Mol Cell 42:561–568.
-
(2011)
Mol Cell
, vol.42
, pp. 561-568
-
-
Bell, E.L.1
Guarente, L.2
-
15
-
-
84890565652
-
Intra-hippocampal transplantation of neural precursor cells with transgenic over-expression of IL-1 receptor antagonist rescues memory and neurogenesis impairments in an Alzheimer's disease model
-
Ben-Menachem-Zidon O, Ben-Menahem Y, Ben-Hur T, Yirmiya R (2014) Intra-hippocampal transplantation of neural precursor cells with transgenic over-expression of IL-1 receptor antagonist rescues memory and neurogenesis impairments in an Alzheimer's disease model. Neuropsychopharmacology 39:401–414.
-
(2014)
Neuropsychopharmacology
, vol.39
, pp. 401-414
-
-
Ben-Menachem-Zidon, O.1
Ben-Menahem, Y.2
Ben-Hur, T.3
Yirmiya, R.4
-
17
-
-
84886951814
-
Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition
-
Bernardo TC, Cunha-Oliveira T, Serafim TL, Holy J, Krasutsky D, Kolomitsyna O et al (2013) Dimethylaminopyridine derivatives of lupane triterpenoids cause mitochondrial disruption and induce the permeability transition. Bioorg Med Chem 21:7239–7249.
-
(2013)
Bioorg Med Chem
, vol.21
, pp. 7239-7249
-
-
Bernardo, T.C.1
Cunha-Oliveira, T.2
Serafim, T.L.3
Holy, J.4
Krasutsky, D.5
Kolomitsyna, O.6
-
18
-
-
50249135503
-
Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease
-
Bezprozvanny I, Mattson MP (2008) Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease. Trends Neurosci 31:454–463.
-
(2008)
Trends Neurosci
, vol.31
, pp. 454-463
-
-
Bezprozvanny, I.1
Mattson, M.P.2
-
19
-
-
0037101606
-
Presynaptic mitochondrial calcium sequestration influences transmission at mammalian central synapses
-
Billups B, Forsythe ID (2002) Presynaptic mitochondrial calcium sequestration influences transmission at mammalian central synapses. J Neurosci 22:5840–5847.
-
(2002)
J Neurosci
, vol.22
, pp. 5840-5847
-
-
Billups, B.1
Forsythe, I.D.2
-
20
-
-
0022365608
-
The distribution of tau in the mammalian central nervous system
-
Binder LI, Frankfurter A, Rebhun LI (1985) The distribution of tau in the mammalian central nervous system. J Cell Biol 101:1371–1378.
-
(1985)
J Cell Biol
, vol.101
, pp. 1371-1378
-
-
Binder, L.I.1
Frankfurter, A.2
Rebhun, L.I.3
-
21
-
-
84862088615
-
Inhibition of microglial activation protects hippocampal neurogenesis and improves cognitive deficits in a transgenic mouse model for Alzheimer's disease
-
Biscaro B, Lindvall O, Tesco G, Ekdahl CT, Nitsch RM (2012) Inhibition of microglial activation protects hippocampal neurogenesis and improves cognitive deficits in a transgenic mouse model for Alzheimer's disease. Neurodegener Dis 9:187–198.
-
(2012)
Neurodegener Dis
, vol.9
, pp. 187-198
-
-
Biscaro, B.1
Lindvall, O.2
Tesco, G.3
Ekdahl, C.T.4
Nitsch, R.M.5
-
22
-
-
84899019792
-
Amyloid-β and tau: the trigger and bullet in Alzheimer disease pathogenesis
-
Bloom GS (2014) Amyloid-β and tau: the trigger and bullet in Alzheimer disease pathogenesis. JAMA Neurol 71:505–508.
-
(2014)
JAMA Neurol
, vol.71
, pp. 505-508
-
-
Bloom, G.S.1
-
23
-
-
84953210392
-
Exercise-induced neuroprotection of hippocampus in APP/PS1 transgenic mice via upregulation of mitochondrial 8-oxoguanine DNA glycosylase
-
Bo H, Kang W, Jiang N, Wang X, Zhang Y, Ji LL (2014) Exercise-induced neuroprotection of hippocampus in APP/PS1 transgenic mice via upregulation of mitochondrial 8-oxoguanine DNA glycosylase. Oxid Med Cell Longev 2014:834502.
-
(2014)
Oxid Med Cell Longev
, vol.2014
, pp. 834502
-
-
Bo, H.1
Kang, W.2
Jiang, N.3
Wang, X.4
Zhang, Y.5
Ji, L.L.6
-
24
-
-
34447308750
-
A systems biology analysis of protein-protein interactions between yeast superoxide dismutases and DNA repair pathways
-
Bonatto D (2007) A systems biology analysis of protein-protein interactions between yeast superoxide dismutases and DNA repair pathways. Free Radic Biol Med 43:557–567.
-
(2007)
Free Radic Biol Med
, vol.43
, pp. 557-567
-
-
Bonatto, D.1
-
25
-
-
0036231792
-
Cytochrome c oxidase and mitochondrial F1F0-ATPase (ATP synthase) activities in platelets and brain from patients with Alzheimer's disease
-
Bosetti F, Brizzi F, Barogi S, Mancuso M, Siciliano G, Tendi EA et al (2002) Cytochrome c oxidase and mitochondrial F1F0-ATPase (ATP synthase) activities in platelets and brain from patients with Alzheimer's disease. Neurobiol Aging 23:371–376.
-
(2002)
Neurobiol Aging
, vol.23
, pp. 371-376
-
-
Bosetti, F.1
Brizzi, F.2
Barogi, S.3
Mancuso, M.4
Siciliano, G.5
Tendi, E.A.6
-
26
-
-
0028362458
-
A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads
-
Braak F, Braak H, Mandelkow E-M (1994) A sequence of cytoskeleton changes related to the formation of neurofibrillary tangles and neuropil threads. Acta Neuropathol 87:554–567.
-
(1994)
Acta Neuropathol
, vol.87
, pp. 554-567
-
-
Braak, F.1
Braak, H.2
Mandelkow, E.-M.3
-
28
-
-
0025965521
-
Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion
-
Breen K, Bruce M, Anderton B (1991) Beta amyloid precursor protein mediates neuronal cell-cell and cell-surface adhesion. J Neurosci Res 28:90–100.
-
(1991)
J Neurosci Res
, vol.28
, pp. 90-100
-
-
Breen, K.1
Bruce, M.2
Anderton, B.3
-
29
-
-
84937019697
-
Mitochondrial dysfunction contributes to the pathogenesis of Alzheimer's disease
-
Cabezas-Opazo FA, Vergara-Pulgar K, Pérez MJ, Jara C, Osorio-Fuentealba C, Quintanilla RA (2015) Mitochondrial dysfunction contributes to the pathogenesis of Alzheimer's disease. Oxid Med Cell Longev 2015:509654.
-
(2015)
Oxid Med Cell Longev
, vol.2015
, pp. 509654
-
-
Cabezas-Opazo, F.A.1
Vergara-Pulgar, K.2
Pérez, M.J.3
Jara, C.4
Osorio-Fuentealba, C.5
Quintanilla, R.A.6
-
30
-
-
84958748059
-
Alterations in mitochondrial quality control in Alzheimer's disease
-
Cai Q, Tammineni P (2016) Alterations in mitochondrial quality control in Alzheimer's disease. Front Cell Neurosci 10:24.
-
(2016)
Front Cell Neurosci
, vol.10
, pp. 24
-
-
Cai, Q.1
Tammineni, P.2
-
31
-
-
81255190781
-
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
-
Calkins MJ, Manczak M, Mao P, Shirendeb U, Reddy PH (2011) Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease. Hum Mol Genet 20:4515–4529.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 4515-4529
-
-
Calkins, M.J.1
Manczak, M.2
Mao, P.3
Shirendeb, U.4
Reddy, P.H.5
-
32
-
-
79751537405
-
Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons
-
Calkins MJ, Reddy PH (2011) Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons. Biochim Biophys Acta 1812:507–513.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 507-513
-
-
Calkins, M.J.1
Reddy, P.H.2
-
33
-
-
79960557491
-
Assessment of newly synthesized mitochondrial DNA using BrdU labeling in primary neurons from Alzheimer's disease mice: implications for impaired mitochondrial biogenesis and synaptic damage
-
Calkins MJ, Reddy PH (2011) Assessment of newly synthesized mitochondrial DNA using BrdU labeling in primary neurons from Alzheimer's disease mice: implications for impaired mitochondrial biogenesis and synaptic damage. Biochim Biophys Acta 1812:1182–1189.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 1182-1189
-
-
Calkins, M.J.1
Reddy, P.H.2
-
35
-
-
28744449206
-
Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease
-
Caspersen C, Wang N, Yao J, Sosunov A, Chen X, Lustbader JW et al (2005) Mitochondrial Abeta: a potential focal point for neuronal metabolic dysfunction in Alzheimer's disease. Faseb J 19:2040–2041.
-
(2005)
Faseb J
, vol.19
, pp. 2040-2041
-
-
Caspersen, C.1
Wang, N.2
Yao, J.3
Sosunov, A.4
Chen, X.5
Lustbader, J.W.6
-
36
-
-
84886783440
-
Key role of mitochondria in Alzheimer's disease synaptic dysfunction
-
Cavallucci V, Ferraina C, D'Amelio M (2013) Key role of mitochondria in Alzheimer's disease synaptic dysfunction. Curr Pharm Des 19:6440–6450.
-
(2013)
Curr Pharm Des
, vol.19
, pp. 6440-6450
-
-
Cavallucci, V.1
Ferraina, C.2
D'Amelio, M.3
-
37
-
-
84859709003
-
Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell death
-
Cha M-Y, Han S-H, Son SM, Hong H-S, Choi Y-J, Byun J et al (2012) Mitochondria-specific accumulation of amyloid β induces mitochondrial dysfunction leading to apoptotic cell death. PLoS One 7:e34929.
-
(2012)
PLoS One
, vol.7
-
-
Cha, M.-Y.1
Han, S.-H.2
Son, S.M.3
Hong, H.-S.4
Choi, Y.-J.5
Byun, J.6
-
38
-
-
33745274726
-
Mitochondria: dynamic organelles in disease, aging, and development
-
Chan DC (2006) Mitochondria: dynamic organelles in disease, aging, and development. Cell 125:1241–1252.
-
(2006)
Cell
, vol.125
, pp. 1241-1252
-
-
Chan, D.C.1
-
39
-
-
55049110863
-
Relationship of serum brain-derived neurotrophic factor (BDNF) and health-related lifestyle in healthy human subjects
-
Chan KL, Tong KY, Yip SP (2008) Relationship of serum brain-derived neurotrophic factor (BDNF) and health-related lifestyle in healthy human subjects. Neurosci Lett 447:124–128.
-
(2008)
Neurosci Lett
, vol.447
, pp. 124-128
-
-
Chan, K.L.1
Tong, K.Y.2
Yip, S.P.3
-
41
-
-
77951096150
-
Mitochondrial dynamics–fusion, fission, movement, and mitophagy–in neurodegenerative diseases
-
Chen H, Chan DC (2009) Mitochondrial dynamics–fusion, fission, movement, and mitophagy–in neurodegenerative diseases. Hum Mol Genet 18:R169–RR76.
-
(2009)
Hum Mol Genet
, vol.18
, pp. RR76-R169
-
-
Chen, H.1
Chan, D.C.2
-
42
-
-
76949097532
-
The combination of exercise training and alpha-lipoic acid treatment has therapeutic effects on the pathogenic phenotypes of Alzheimer's disease in NSE/APPsw-transgenic mice
-
Cho JY, Um HS, Kang EB, Cho IH, Kim CH, Cho JS et al (2010) The combination of exercise training and alpha-lipoic acid treatment has therapeutic effects on the pathogenic phenotypes of Alzheimer's disease in NSE/APPsw-transgenic mice. Int J Mol Med 25:337–346.
-
(2010)
Int J Mol Med
, vol.25
, pp. 337-346
-
-
Cho, J.Y.1
Um, H.S.2
Kang, E.B.3
Cho, I.H.4
Kim, C.H.5
Cho, J.S.6
-
43
-
-
70249114428
-
Contribution of glutathione status to oxidant-induced mitochondrial DNA damage in colonic epithelial cells
-
Circu ML, Moyer MP, Harrison L, Aw TY (2009) Contribution of glutathione status to oxidant-induced mitochondrial DNA damage in colonic epithelial cells. Free Radic Biol Med 47:1190–1198.
-
(2009)
Free Radic Biol Med
, vol.47
, pp. 1190-1198
-
-
Circu, M.L.1
Moyer, M.P.2
Harrison, L.3
Aw, T.Y.4
-
44
-
-
79953275008
-
Genetic influences on exercise-induced adult hippocampal neurogenesis across 12 divergent mouse strains
-
Clark PJ, Kohman RA, Miller DS, Bhattacharya TK, Brzezinska WJ, Rhodes JS (2011) Genetic influences on exercise-induced adult hippocampal neurogenesis across 12 divergent mouse strains. Genes Brain Behav 10:345–353.
-
(2011)
Genes Brain Behav
, vol.10
, pp. 345-353
-
-
Clark, P.J.1
Kohman, R.A.2
Miller, D.S.3
Bhattacharya, T.K.4
Brzezinska, W.J.5
Rhodes, J.S.6
-
45
-
-
84947045067
-
Metabolomic analysis of exercise effects in the POLG mitochondrial DNA mutator mouse brain
-
Clark-Matott J, Saleem A, Dai Y, Shurubor Y, Ma X, Safdar A et al (2015) Metabolomic analysis of exercise effects in the POLG mitochondrial DNA mutator mouse brain. Neurobiol Aging 36:2972–2983.
-
(2015)
Neurobiol Aging
, vol.36
, pp. 2972-2983
-
-
Clark-Matott, J.1
Saleem, A.2
Dai, Y.3
Shurubor, Y.4
Ma, X.5
Safdar, A.6
-
46
-
-
84893929527
-
Acute aerobic exercise increases brain-derived neurotrophic factor levels in elderly with Alzheimer's disease
-
Coelho FG, Vital TM, Stein AM, Arantes FJ, Rueda AV, Camarini R et al (2014) Acute aerobic exercise increases brain-derived neurotrophic factor levels in elderly with Alzheimer's disease. J Alzheimers Dis 39:401–408.
-
(2014)
J Alzheimers Dis
, vol.39
, pp. 401-408
-
-
Coelho, F.G.1
Vital, T.M.2
Stein, A.M.3
Arantes, F.J.4
Rueda, A.V.5
Camarini, R.6
-
47
-
-
16544362766
-
Neurocognitive aging and cardiovascular fitness: recent findings and future directions
-
Colcombe SJ, Kramer AF, McAuley E, Erickson KI, Scalf P (2004) Neurocognitive aging and cardiovascular fitness: recent findings and future directions. J Mol Neurosci: MN 24:9–14.
-
(2004)
J Mol Neurosci: MN
, vol.24
, pp. 9-14
-
-
Colcombe, S.J.1
Kramer, A.F.2
McAuley, E.3
Erickson, K.I.4
Scalf, P.5
-
48
-
-
0030769092
-
Alzheimer's Aβ (1–42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells
-
Cook DG, Forman MS, Sung JC, Leight S, Kolson DL, Iwatsubo T et al (1997) Alzheimer's Aβ (1–42) is generated in the endoplasmic reticulum/intermediate compartment of NT2N cells. Nat Med 3:1021–1023.
-
(1997)
Nat Med
, vol.3
, pp. 1021-1023
-
-
Cook, D.G.1
Forman, M.S.2
Sung, J.C.3
Leight, S.4
Kolson, D.L.5
Iwatsubo, T.6
-
49
-
-
84867725518
-
Alzheimer disease as a vascular disorder: where do mitochondria fit?
-
Correia SC, Santos RX, Cardoso S, Carvalho C, Candeias E, Duarte AI et al (2012) Alzheimer disease as a vascular disorder: where do mitochondria fit? Exp Gerontol 47:878–886.
-
(2012)
Exp Gerontol
, vol.47
, pp. 878-886
-
-
Correia, S.C.1
Santos, R.X.2
Cardoso, S.3
Carvalho, C.4
Candeias, E.5
Duarte, A.I.6
-
50
-
-
84878623135
-
Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease
-
Correia SC, Santos RX, Santos MS, Casadesus G, Lamanna JC, Perry G et al (2013) Mitochondrial abnormalities in a streptozotocin-induced rat model of sporadic Alzheimer's disease. Curr Alzheimer Res 10:406–419.
-
(2013)
Curr Alzheimer Res
, vol.10
, pp. 406-419
-
-
Correia, S.C.1
Santos, R.X.2
Santos, M.S.3
Casadesus, G.4
Lamanna, J.C.5
Perry, G.6
-
51
-
-
45649083723
-
Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models
-
Corsetti V, Amadoro G, Gentile A, Capsoni S, Ciotti M, Cencioni M et al (2008) Identification of a caspase-derived N-terminal tau fragment in cellular and animal Alzheimer's disease models. Mol Cell Neurosci 38:381–392.
-
(2008)
Mol Cell Neurosci
, vol.38
, pp. 381-392
-
-
Corsetti, V.1
Amadoro, G.2
Gentile, A.3
Capsoni, S.4
Ciotti, M.5
Cencioni, M.6
-
52
-
-
84888223184
-
AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons
-
Amadoro G, Corsetti V, Florenzano F, Atlante A, Ciotti MT, Mongiardi MP et al (2014) AD-linked, toxic NH2 human tau affects the quality control of mitochondria in neurons. Neurobiol Dis 62:489–507.
-
(2014)
Neurobiol Dis
, vol.62
, pp. 489-507
-
-
Amadoro, G.1
Corsetti, V.2
Florenzano, F.3
Atlante, A.4
Ciotti, M.T.5
Mongiardi, M.P.6
-
53
-
-
84859421209
-
A mitochondrial etiology of Alzheimer and Parkinson disease
-
Coskun P, Wyrembak J, Schriner SE, Chen HW, Marciniack C, Laferla F et al (2012) A mitochondrial etiology of Alzheimer and Parkinson disease. Biochim Biophys Acta 1820:553–564.
-
(2012)
Biochim Biophys Acta
, vol.1820
, pp. 553-564
-
-
Coskun, P.1
Wyrembak, J.2
Schriner, S.E.3
Chen, H.W.4
Marciniack, C.5
Laferla, F.6
-
54
-
-
3242668604
-
Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication
-
Coskun PE, Beal MF, Wallace DC (2004) Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication. Proc Natl Acad Sci U S A 101:10726–10731.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 10726-10731
-
-
Coskun, P.E.1
Beal, M.F.2
Wallace, D.C.3
-
55
-
-
77956197653
-
Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia
-
Coskun PE, Wyrembak J, Derbereva O, Melkonian G, Doran E, Lott IT et al (2010) Systemic mitochondrial dysfunction and the etiology of Alzheimer's disease and down syndrome dementia. J Alzheimers Dis 20 Suppl 2:S293–S310.
-
(2010)
J Alzheimers Dis
, vol.20 Suppl 2
, pp. S293-S310
-
-
Coskun, P.E.1
Wyrembak, J.2
Derbereva, O.3
Melkonian, G.4
Doran, E.5
Lott, I.T.6
-
56
-
-
81355133149
-
Environmental enrichment fails to rescue working memory deficits, neuron loss, and neurogenesis in APP/PS1KI mice
-
Cotel MC, Jawhar S, Christensen DZ, Bayer TA, Wirths O (2012) Environmental enrichment fails to rescue working memory deficits, neuron loss, and neurogenesis in APP/PS1KI mice. Neurobiol Aging 33:96–107.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 96-107
-
-
Cotel, M.C.1
Jawhar, S.2
Christensen, D.Z.3
Bayer, T.A.4
Wirths, O.5
-
57
-
-
76649138004
-
Running enhances spatial pattern separation in mice
-
Creer DJ, Romberg C, Saksida LM, van Praag H, Bussey TJ (2010) Running enhances spatial pattern separation in mice. Proc Natl Acad Sci U S A 107:2367–2372.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 2367-2372
-
-
Creer, D.J.1
Romberg, C.2
Saksida, L.M.3
van Praag, H.4
Bussey, T.J.5
-
58
-
-
77955824765
-
An intimate liaison: spatial organization of the endoplasmic reticulum–mitochondria relationship
-
de Brito OM, Scorrano L (2010) An intimate liaison: spatial organization of the endoplasmic reticulum–mitochondria relationship. EMBO J 29:2715–2723.
-
(2010)
EMBO J
, vol.29
, pp. 2715-2723
-
-
de Brito, O.M.1
Scorrano, L.2
-
59
-
-
0036447681
-
Vascular basis of Alzheimer's pathogenesis
-
de la Torre JC (2002) Vascular basis of Alzheimer's pathogenesis. Ann N Y Acad Sci 977:196–215.
-
(2002)
Ann N Y Acad Sci
, vol.977
, pp. 196-215
-
-
de la Torre, J.C.1
-
60
-
-
84890559348
-
Alzheimer's as a metabolic disease
-
Demetrius LA, Driver J (2013) Alzheimer's as a metabolic disease. Biogerontology 14:641–649.
-
(2013)
Biogerontology
, vol.14
, pp. 641-649
-
-
Demetrius, L.A.1
Driver, J.2
-
61
-
-
84915756478
-
Preventing Alzheimer's disease by means of natural selection
-
Demetrius LA, Driver JA (2015) Preventing Alzheimer's disease by means of natural selection. J R Soc Interface 12:20140919.
-
(2015)
J R Soc Interface
, vol.12
, pp. 20140919
-
-
Demetrius, L.A.1
Driver, J.A.2
-
62
-
-
84940902321
-
Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect
-
Demetrius LA, Magistretti PJ, Pellerin L (2014) Alzheimer's disease: the amyloid hypothesis and the Inverse Warburg effect. Front Physiol 5:522.
-
(2014)
Front Physiol
, vol.5
, pp. 522
-
-
Demetrius, L.A.1
Magistretti, P.J.2
Pellerin, L.3
-
63
-
-
84878252585
-
An inverse-Warburg effect and the origin of Alzheimer's disease
-
Demetrius LA, Simon DK (2012) An inverse-Warburg effect and the origin of Alzheimer's disease. Biogerontology 13:583–594.
-
(2012)
Biogerontology
, vol.13
, pp. 583-594
-
-
Demetrius, L.A.1
Simon, D.K.2
-
64
-
-
35448960851
-
Functions and dysfunctions of mitochondrial dynamics
-
Detmer SA, Chan DC (2007) Functions and dysfunctions of mitochondrial dynamics. Nat Rev Mol Cell Biol 8:870–879.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 870-879
-
-
Detmer, S.A.1
Chan, D.C.2
-
65
-
-
33748283747
-
Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction
-
Devi L, Prabhu BM, Galati DF, Avadhani NG, Anandatheerthavarada HK (2006) Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction. J Neurosci 26:9057–9068.
-
(2006)
J Neurosci
, vol.26
, pp. 9057-9068
-
-
Devi, L.1
Prabhu, B.M.2
Galati, D.F.3
Avadhani, N.G.4
Anandatheerthavarada, H.K.5
-
66
-
-
54849438798
-
Exercise-induced synaptogenesis in the hippocampus is dependent on UCP2-regulated mitochondrial adaptation
-
Dietrich MO, Andrews ZB, Horvath TL (2008) Exercise-induced synaptogenesis in the hippocampus is dependent on UCP2-regulated mitochondrial adaptation. J Neurosci 28:10766–10771.
-
(2008)
J Neurosci
, vol.28
, pp. 10766-10771
-
-
Dietrich, M.O.1
Andrews, Z.B.2
Horvath, T.L.3
-
67
-
-
33748742072
-
Exercise affects energy metabolism and neural plasticity-related proteins in the hippocampus as revealed by proteomic analysis
-
Ding Q, Vaynman S, Souda P, Whitelegge JP, Gomez-Pinilla F (2006) Exercise affects energy metabolism and neural plasticity-related proteins in the hippocampus as revealed by proteomic analysis. Eur J Neurosci 24:1265–1276.
-
(2006)
Eur J Neurosci
, vol.24
, pp. 1265-1276
-
-
Ding, Q.1
Vaynman, S.2
Souda, P.3
Whitelegge, J.P.4
Gomez-Pinilla, F.5
-
68
-
-
77956197971
-
Mitochondrial amyloid-β levels are associated with the extent of mitochondrial dysfunction in different brain regions and the degree of cognitive impairment in Alzheimer's transgenic mice
-
Dragicevic N, Mamcarz M, Zhu Y, Buzzeo R, Tan J, Arendash GW et al (2010) Mitochondrial amyloid-β levels are associated with the extent of mitochondrial dysfunction in different brain regions and the degree of cognitive impairment in Alzheimer's transgenic mice. J Alzheimer's Dis 20:535–550.
-
(2010)
J Alzheimer's Dis
, vol.20
, pp. 535-550
-
-
Dragicevic, N.1
Mamcarz, M.2
Zhu, Y.3
Buzzeo, R.4
Tan, J.5
Arendash, G.W.6
-
69
-
-
0036086130
-
Free radicals in the physiological control of cell function
-
Dröge W (2002) Free radicals in the physiological control of cell function. Physiol Rev 82:47–95.
-
(2002)
Physiol Rev
, vol.82
, pp. 47-95
-
-
Dröge, W.1
-
70
-
-
53549129483
-
Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease
-
Du H, Guo L, Fang F, Chen D, Sosunov AA, McKhann GM et al (2008) Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease. Nat Med 14:1097–1105.
-
(2008)
Nat Med
, vol.14
, pp. 1097-1105
-
-
Du, H.1
Guo, L.2
Fang, F.3
Chen, D.4
Sosunov, A.A.5
McKhann, G.M.6
-
71
-
-
78649815388
-
Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model
-
Du H, Guo L, Yan S, Sosunov AA, McKhann GM, Yan SS (2010) Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model. Proc Natl Acad Sci U S A 107:18670–18675.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 18670-18675
-
-
Du, H.1
Guo, L.2
Yan, S.3
Sosunov, A.A.4
McKhann, G.M.5
Yan, S.S.6
-
72
-
-
72149118206
-
Mitochondrial permeability transition pore in Alzheimer's disease: cyclophilin D and amyloid beta
-
Du H, Yan SS (2010) Mitochondrial permeability transition pore in Alzheimer's disease: cyclophilin D and amyloid beta. Biochim Biophys Acta 1802:198–204.
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 198-204
-
-
Du, H.1
Yan, S.S.2
-
73
-
-
39449138356
-
Tau inhibits anterograde axonal transport and perturbs stability in growing axonal neurites in part by displacing kinesin cargo: neurofilaments attenuate tau-mediated neurite instability
-
Dubey M, Chaudhury P, Kabiru H, Shea TB (2008) Tau inhibits anterograde axonal transport and perturbs stability in growing axonal neurites in part by displacing kinesin cargo: neurofilaments attenuate tau-mediated neurite instability. Cell Motil Cytoskel 65:89–99.
-
(2008)
Cell Motil Cytoskel
, vol.65
, pp. 89-99
-
-
Dubey, M.1
Chaudhury, P.2
Kabiru, H.3
Shea, T.B.4
-
74
-
-
81455157378
-
Mitochondrial dysfunction—the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-beta toxicity
-
Eckert A, Schmitt K, Götz J (2011) Mitochondrial dysfunction—the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-beta toxicity. Alzheimers Res Ther 3:1186.
-
(2011)
Alzheimers Res Ther
, vol.3
, pp. 1186
-
-
Eckert, A.1
Schmitt, K.2
Götz, J.3
-
75
-
-
33646186499
-
Exercise, cognition and Alzheimer's disease: more is not necessarily better
-
Eggermont L, Swaab D, Luiten P, Scherder E (2006) Exercise, cognition and Alzheimer's disease: more is not necessarily better. Neurosci Biobehav Rev 30:562–575.
-
(2006)
Neurosci Biobehav Rev
, vol.30
, pp. 562-575
-
-
Eggermont, L.1
Swaab, D.2
Luiten, P.3
Scherder, E.4
-
76
-
-
84947792370
-
Short-term treadmill exercise increased tau insolubility and neuroinflammation in tauopathy model mice
-
Elahi M, Motoi Y, Matsumoto SE, Hasan Z, Ishiguro K, Hattori N (2016) Short-term treadmill exercise increased tau insolubility and neuroinflammation in tauopathy model mice. Neurosci Lett 610:207–212.
-
(2016)
Neurosci Lett
, vol.610
, pp. 207-212
-
-
Elahi, M.1
Motoi, Y.2
Matsumoto, S.E.3
Hasan, Z.4
Ishiguro, K.5
Hattori, N.6
-
77
-
-
79952611543
-
Exercise training increases size of hippocampus and improves memory
-
Erickson KI, Voss MW, Prakash RS, Basak C, Szabo A, Chaddock L et al (2011) Exercise training increases size of hippocampus and improves memory. Proc Natl Acad Sci U S A 108:3017–3022.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 3017-3022
-
-
Erickson, K.I.1
Voss, M.W.2
Prakash, R.S.3
Basak, C.4
Szabo, A.5
Chaddock, L.6
-
78
-
-
70449435581
-
Altered mitochondria, energy metabolism, voltage-dependent anion channel, and lipid rafts converge to exhaust neurons in Alzheimer's disease
-
Ferrer I (2009) Altered mitochondria, energy metabolism, voltage-dependent anion channel, and lipid rafts converge to exhaust neurons in Alzheimer's disease. J Bioenerg Biomembr 41:425–431.
-
(2009)
J Bioenerg Biomembr
, vol.41
, pp. 425-431
-
-
Ferrer, I.1
-
79
-
-
84890092993
-
Role of exercise-induced reactive oxygen species in the modulation of heat shock protein response
-
Fittipaldi S, Dimauro I, Mercatelli N, Caporossi D (2014) Role of exercise-induced reactive oxygen species in the modulation of heat shock protein response. Free Radic Res 48:52–70.
-
(2014)
Free Radic Res
, vol.48
, pp. 52-70
-
-
Fittipaldi, S.1
Dimauro, I.2
Mercatelli, N.3
Caporossi, D.4
-
80
-
-
84906666540
-
Mitochondrial dysfunction: cause and consequence of Alzheimer's disease
-
Friedland-Leuner K, Stockburger C, Denzer I, Eckert GP, Muller WE (2014) Mitochondrial dysfunction: cause and consequence of Alzheimer's disease. Prog Mol Biol Transl Sci 127:183–210.
-
(2014)
Prog Mol Biol Transl Sci
, vol.127
, pp. 183-210
-
-
Friedland-Leuner, K.1
Stockburger, C.2
Denzer, I.3
Eckert, G.P.4
Muller, W.E.5
-
82
-
-
84958202226
-
Oxidative stress is a central target for physical exercise neuroprotection against pathological brain aging
-
Garcia-Mesa Y, Colie S, Corpas R, Cristofol R, Comellas F, Nebreda AR et al (2016) Oxidative stress is a central target for physical exercise neuroprotection against pathological brain aging. J Gerontol a Biol Sci Med Sci 71:40–49.
-
(2016)
J Gerontol a Biol Sci Med Sci
, vol.71
, pp. 40-49
-
-
Garcia-Mesa, Y.1
Colie, S.2
Corpas, R.3
Cristofol, R.4
Comellas, F.5
Nebreda, A.R.6
-
83
-
-
84859485513
-
Melatonin plus physical exercise are highly neuroprotective in the 3xTg-AD mouse
-
Garcia-Mesa Y, Gimenez-Llort L, Lopez LC, Venegas C, Cristofol R, Escames G et al (2012) Melatonin plus physical exercise are highly neuroprotective in the 3xTg-AD mouse. Neurobiol Aging 33:1124–1129.
-
(2012)
Neurobiol Aging
, vol.33
, pp. 1124-1129
-
-
Garcia-Mesa, Y.1
Gimenez-Llort, L.2
Lopez, L.C.3
Venegas, C.4
Cristofol, R.5
Escames, G.6
-
84
-
-
79957791224
-
Physical exercise protects against Alzheimer's disease in 3xTg-AD mice
-
Garcia-Mesa Y, Lopez-Ramos JC, Gimenez-Llort L, Revilla S, Guerra R, Gruart A et al (2011) Physical exercise protects against Alzheimer's disease in 3xTg-AD mice. J Alzheimers Dis 24:421–454.
-
(2011)
J Alzheimers Dis
, vol.24
, pp. 421-454
-
-
Garcia-Mesa, Y.1
Lopez-Ramos, J.C.2
Gimenez-Llort, L.3
Revilla, S.4
Guerra, R.5
Gruart, A.6
-
85
-
-
84901195109
-
Physical exercise neuroprotects ovariectomized 3xTg-AD mice through BDNF mechanisms
-
Garcia-Mesa Y, Pareja-Galeano H, Bonet-Costa V, Revilla S, Gomez-Cabrera MC, Gambini J et al (2014) Physical exercise neuroprotects ovariectomized 3xTg-AD mice through BDNF mechanisms. Psychoneuroendocrinology 45:154–166.
-
(2014)
Psychoneuroendocrinology
, vol.45
, pp. 154-166
-
-
Garcia-Mesa, Y.1
Pareja-Galeano, H.2
Bonet-Costa, V.3
Revilla, S.4
Gomez-Cabrera, M.C.5
Gambini, J.6
-
86
-
-
84890803688
-
Autophagy and apoptosis dysfunction in neurodegenerative disorders
-
Ghavami S, Shojaei S, Yeganeh B, Ande SR, Jangamreddy JR, Mehrpour M et al (2014) Autophagy and apoptosis dysfunction in neurodegenerative disorders. Prog Neurobiol 112:24–49.
-
(2014)
Prog Neurobiol
, vol.112
, pp. 24-49
-
-
Ghavami, S.1
Shojaei, S.2
Yeganeh, B.3
Ande, S.R.4
Jangamreddy, J.R.5
Mehrpour, M.6
-
87
-
-
78349250222
-
Gender-Specific Neuroimmunoendocrine Response to Treadmill Exercise in 3xTg-AD Mice
-
Gimenez-Llort L, Garcia Y, Buccieri K, Revilla S, Sunol C, Cristofol R et al (2010) Gender-Specific Neuroimmunoendocrine Response to Treadmill Exercise in 3xTg-AD Mice. Int J Alzheimers Dis 2010:128354.
-
(2010)
Int J Alzheimers Dis
, vol.2010
, pp. 128354
-
-
Gimenez-Llort, L.1
Garcia, Y.2
Buccieri, K.3
Revilla, S.4
Sunol, C.5
Cristofol, R.6
-
88
-
-
84864150633
-
Peripheral immune system and neuroimmune communication impairment in a mouse model of Alzheimer's disease
-
Gimenez-Llort L, Mate I, Manassra R, Vida C, De la Fuente M (2012) Peripheral immune system and neuroimmune communication impairment in a mouse model of Alzheimer's disease. Ann N Y Acad Sci 1262:74–84.
-
(2012)
Ann N Y Acad Sci
, vol.1262
, pp. 74-84
-
-
Gimenez-Llort, L.1
Mate, I.2
Manassra, R.3
Vida, C.4
De la Fuente, M.5
-
89
-
-
14644436322
-
Homing in on intracellular Abeta?
-
Golde TE, Janus C (2005) Homing in on intracellular Abeta? Neuron 45:639–642.
-
(2005)
Neuron
, vol.45
, pp. 639-642
-
-
Golde, T.E.1
Janus, C.2
-
90
-
-
33847732649
-
Ultrastructural localization of intraneuronal Abeta-peptide in Alzheimer disease brains
-
Gomez-Ramos P, Asuncion Moran M (2007) Ultrastructural localization of intraneuronal Abeta-peptide in Alzheimer disease brains. J Alzheimers Dis 11:53–59.
-
(2007)
J Alzheimers Dis
, vol.11
, pp. 53-59
-
-
Gomez-Ramos, P.1
Asuncion Moran, M.2
-
91
-
-
0033582159
-
Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer β-amyloid peptides
-
Greenfield JP, Tsai J, Gouras GK, Hai B, Thinakaran G, Checler F et al (1999) Endoplasmic reticulum and trans-Golgi network generate distinct populations of Alzheimer β-amyloid peptides. Proc Natl Acad Sci 96:742–747.
-
(1999)
Proc Natl Acad Sci
, vol.96
, pp. 742-747
-
-
Greenfield, J.P.1
Tsai, J.2
Gouras, G.K.3
Hai, B.4
Thinakaran, G.5
Checler, F.6
-
92
-
-
84988551838
-
Mitochondrial dysfunction: the missing link between aging and sporadic Alzheimer's disease
-
Grimm A, Friedland K, Eckert A (2015) Mitochondrial dysfunction: the missing link between aging and sporadic Alzheimer's disease. Biogerontology 16:801.
-
(2015)
Biogerontology
, vol.16
, pp. 801
-
-
Grimm, A.1
Friedland, K.2
Eckert, A.3
-
93
-
-
84889860617
-
Oxidative stress, mitochondrial damage and neurodegenerative diseases
-
Guo C, Sun L, Chen X, Zhang D (2013) Oxidative stress, mitochondrial damage and neurodegenerative diseases. Neural Regen Res 8:2003–2014.
-
(2013)
Neural Regen Res
, vol.8
, pp. 2003-2014
-
-
Guo, C.1
Sun, L.2
Chen, X.3
Zhang, D.4
-
94
-
-
62249177925
-
Physical activity and risk of neurodegenerative disease: a systematic review of prospective evidence
-
Hamer M, Chida Y (2009) Physical activity and risk of neurodegenerative disease: a systematic review of prospective evidence. Psychol Med 39:3–11.
-
(2009)
Psychol Med
, vol.39
, pp. 3-11
-
-
Hamer, M.1
Chida, Y.2
-
95
-
-
84859429769
-
The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease
-
Hamilton A, Holscher C (2012) The effect of ageing on neurogenesis and oxidative stress in the APP(swe)/PS1(deltaE9) mouse model of Alzheimer's disease. Brain Res 1449:83–93.
-
(2012)
Brain Res
, vol.1449
, pp. 83-93
-
-
Hamilton, A.1
Holscher, C.2
-
96
-
-
77956826478
-
Widespread deficits in adult neurogenesis precede plaque and tangle formation in the 3xTg mouse model of Alzheimer's disease
-
Hamilton LK, Aumont A, Julien C, Vadnais A, Calon F, Fernandes KJ (2010) Widespread deficits in adult neurogenesis precede plaque and tangle formation in the 3xTg mouse model of Alzheimer's disease. Eur J Neurosci 32:905–920.
-
(2010)
Eur J Neurosci
, vol.32
, pp. 905-920
-
-
Hamilton, L.K.1
Aumont, A.2
Julien, C.3
Vadnais, A.4
Calon, F.5
Fernandes, K.J.6
-
97
-
-
51349110166
-
The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae
-
Hansson Petersen CA, Alikhani N, Behbahani H, Wiehager B, Pavlov PF, Alafuzoff I et al (2008) The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae. Proc Natl Acad Sci U S A 105:13145–13150.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 13145-13150
-
-
Hansson Petersen, C.A.1
Alikhani, N.2
Behbahani, H.3
Wiehager, B.4
Pavlov, P.F.5
Alafuzoff, I.6
-
98
-
-
0030769091
-
Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 amyloid peptides
-
Hartmann T, Bieger SC, Brühl B, Tienari PJ, Ida N, Allsop D et al (1997) Distinct sites of intracellular production for Alzheimer's disease Aβ40/42 amyloid peptides. Nat Med 3:1016–1020.
-
(1997)
Nat Med
, vol.3
, pp. 1016-1020
-
-
Hartmann, T.1
Bieger, S.C.2
Brühl, B.3
Tienari, P.J.4
Ida, N.5
Allsop, D.6
-
100
-
-
0034329291
-
Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members
-
Heber S, Herms J, Gajic V, Hainfellner J, Aguzzi A, Rülicke T et al (2000) Mice with combined gene knock-outs reveal essential and partially redundant functions of amyloid precursor protein family members. J Neurosci 20:7951–7963.
-
(2000)
J Neurosci
, vol.20
, pp. 7951-7963
-
-
Heber, S.1
Herms, J.2
Gajic, V.3
Hainfellner, J.4
Aguzzi, A.5
Rülicke, T.6
-
101
-
-
84877337663
-
Modulation of the endoplasmic reticulum–mitochondria interface in Alzheimer's disease and related models
-
Hedskog L, Pinho CM, Filadi R, Rönnbäck A, Hertwig L, Wiehager B et al (2013) Modulation of the endoplasmic reticulum–mitochondria interface in Alzheimer's disease and related models. Proc Natl Acad Sci 110:7916–7921.
-
(2013)
Proc Natl Acad Sci
, vol.110
, pp. 7916-7921
-
-
Hedskog, L.1
Pinho, C.M.2
Filadi, R.3
Rönnbäck, A.4
Hertwig, L.5
Wiehager, B.6
-
102
-
-
5344237365
-
The effects of exercise training on elderly persons with cognitive impairment and dementia: a meta-analysis
-
Heyn P, Abreu BC, Ottenbacher KJ (2004) The effects of exercise training on elderly persons with cognitive impairment and dementia: a meta-analysis. Arch Phys Med Rehabil 85:1694–1704.
-
(2004)
Arch Phys Med Rehabil
, vol.85
, pp. 1694-1704
-
-
Heyn, P.1
Abreu, B.C.2
Ottenbacher, K.J.3
-
103
-
-
30544452263
-
The axonal transport of mitochondria
-
Hollenbeck PJ, Saxton WM (2005) The axonal transport of mitochondria. J Cell Sci 118:5411–5419.
-
(2005)
J Cell Sci
, vol.118
, pp. 5411-5419
-
-
Hollenbeck, P.J.1
Saxton, W.M.2
-
104
-
-
84901752701
-
Mitochondrial dysfunctions in neurodegenerative diseases: relevance to Alzheimer's disease
-
Hroudová J, Singh N, Fišar Z (2014) Mitochondrial dysfunctions in neurodegenerative diseases: relevance to Alzheimer's disease. BioMed Res Int 2014:175062.
-
(2014)
BioMed Res Int
, vol.2014
, pp. 175062
-
-
Hroudová, J.1
Singh, N.2
Fišar, Z.3
-
105
-
-
84879781233
-
Exercise counteracts declining hippocampal function in aging and Alzheimer's disease
-
Intlekofer KA, Cotman CW (2013) Exercise counteracts declining hippocampal function in aging and Alzheimer's disease. Neurobiol Dis 57:47–55.
-
(2013)
Neurobiol Dis
, vol.57
, pp. 47-55
-
-
Intlekofer, K.A.1
Cotman, C.W.2
-
106
-
-
19944375450
-
Tau pathology in Alzheimer disease and other tauopathies
-
Iqbal K, Alonso AC, Chen S, Chohan MO, El-Akkad E, Gong C-X et al (2005) Tau pathology in Alzheimer disease and other tauopathies. Biochim Biophys Acta (BBA)-Mol Basis Dis 1739:198–210.
-
(2005)
Biochim Biophys Acta (BBA)-Mol Basis Dis
, vol.1739
, pp. 198-210
-
-
Iqbal, K.1
Alonso, A.C.2
Chen, S.3
Chohan, M.O.4
El-Akkad, E.5
Gong, C.-X.6
-
107
-
-
68249087424
-
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
-
Ishihara N, Nomura M, Jofuku A, Kato H, Suzuki SO, Masuda K et al (2009) Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice. Nat Cell Biol 11:958–966.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 958-966
-
-
Ishihara, N.1
Nomura, M.2
Jofuku, A.3
Kato, H.4
Suzuki, S.O.5
Masuda, K.6
-
108
-
-
0842323739
-
Interplay between mitochondria and cellular calcium signalling
-
Jacobson J, Duchen MR (2004) Interplay between mitochondria and cellular calcium signalling. Mol Cell Biochem 256:209–218.
-
(2004)
Mol Cell Biochem
, vol.256
, pp. 209-218
-
-
Jacobson, J.1
Duchen, M.R.2
-
109
-
-
78449282609
-
Metals, oxidative stress and neurodegenerative disorders
-
Jomova K, Vondrakova D, Lawson M, Valko M (2010) Metals, oxidative stress and neurodegenerative disorders. Mol Cell Biochem 345:91–104.
-
(2010)
Mol Cell Biochem
, vol.345
, pp. 91-104
-
-
Jomova, K.1
Vondrakova, D.2
Lawson, M.3
Valko, M.4
-
110
-
-
33847043933
-
Mitochondria and neuronal activity
-
Kann O, Kovács R (2007) Mitochondria and neuronal activity. Am J Physiol-Cell Physiol 292:C641–CC57.
-
(2007)
Am J Physiol-Cell Physiol
, vol.292
, pp. CC57-C641
-
-
Kann, O.1
Kovács, R.2
-
111
-
-
0042887148
-
Demonstration by FRET of BACE interaction with the amyloid precursor protein at the cell surface and in early endosomes
-
Kinoshita A, Fukumoto H, Shah T, Whelan CM, Irizarry MC, Hyman BT (2003) Demonstration by FRET of BACE interaction with the amyloid precursor protein at the cell surface and in early endosomes. J Cell Sci 116:3339–3346.
-
(2003)
J Cell Sci
, vol.116
, pp. 3339-3346
-
-
Kinoshita, A.1
Fukumoto, H.2
Shah, T.3
Whelan, C.M.4
Irizarry, M.C.5
Hyman, B.T.6
-
112
-
-
44649088895
-
Hippocampal metabolic proteins are modulated in voluntary and treadmill exercise rats
-
Kirchner L, Chen WQ, Afjehi-Sadat L, Viidik A, Skalicky M, Hoger H et al (2008) Hippocampal metabolic proteins are modulated in voluntary and treadmill exercise rats. Exp Neurol 212:145–151.
-
(2008)
Exp Neurol
, vol.212
, pp. 145-151
-
-
Kirchner, L.1
Chen, W.Q.2
Afjehi-Sadat, L.3
Viidik, A.4
Skalicky, M.5
Hoger, H.6
-
113
-
-
84890525351
-
Physical exercise and cognitive performance in the elderly: current perspectives
-
Kirk-Sanchez NJ, McGough EL (2014) Physical exercise and cognitive performance in the elderly: current perspectives. Clin Interv Aging 9:51–62.
-
(2014)
Clin Interv Aging
, vol.9
, pp. 51-62
-
-
Kirk-Sanchez, N.J.1
McGough, E.L.2
-
114
-
-
84904536244
-
Differential role of APP and APLPs for neuromuscular synaptic morphology and function
-
Klevanski M, Saar M, Baumkötter F, Weyer SW, Kins S, Müller UC (2014) Differential role of APP and APLPs for neuromuscular synaptic morphology and function. Mol Cell Neurosci 61:201–210.
-
(2014)
Mol Cell Neurosci
, vol.61
, pp. 201-210
-
-
Klevanski, M.1
Saar, M.2
Baumkötter, F.3
Weyer, S.W.4
Kins, S.5
Müller, U.C.6
-
115
-
-
84884676997
-
Modifications of hippocampal circuits and early disruption of adult neurogenesis in the tg2576 mouse model of Alzheimer's disease
-
Krezymon A, Richetin K, Halley H, Roybon L, Lassalle JM, Frances B et al (2013) Modifications of hippocampal circuits and early disruption of adult neurogenesis in the tg2576 mouse model of Alzheimer's disease. PLoS One 8:e76497.
-
(2013)
PLoS One
, vol.8
-
-
Krezymon, A.1
Richetin, K.2
Halley, H.3
Roybon, L.4
Lassalle, J.M.5
Frances, B.6
-
116
-
-
77955979357
-
Pathways linking Aβ and tau pathologies
-
LaFerla FM (2010) Pathways linking Aβ and tau pathologies. Biochem Soc Trans 38:993–995.
-
(2010)
Biochem Soc Trans
, vol.38
, pp. 993-995
-
-
LaFerla, F.M.1
-
117
-
-
34250819839
-
Intracellular amyloid-beta in Alzheimer's disease
-
LaFerla FM, Green KN, Oddo S (2007) Intracellular amyloid-beta in Alzheimer's disease. Nat Rev Neurosci 8:499–509.
-
(2007)
Nat Rev Neurosci
, vol.8
, pp. 499-509
-
-
LaFerla, F.M.1
Green, K.N.2
Oddo, S.3
-
119
-
-
79957913270
-
Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice
-
Lasagna-Reeves CA, Castillo-Carranza DL, Sengupta U, Clos AL, Jackson GR, Kayed R (2011) Tau oligomers impair memory and induce synaptic and mitochondrial dysfunction in wild-type mice. Mol Neurodegener 6:1–14.
-
(2011)
Mol Neurodegener
, vol.6
, pp. 1-14
-
-
Lasagna-Reeves, C.A.1
Castillo-Carranza, D.L.2
Sengupta, U.3
Clos, A.L.4
Jackson, G.R.5
Kayed, R.6
-
120
-
-
84884904327
-
Amyloid precursor proteins are constituents of the presynaptic active zone
-
Laßek M, Weingarten J, Einsfelder U, Brendel P, Müller U, Volknandt W (2013) Amyloid precursor proteins are constituents of the presynaptic active zone. J Neurochem 127:48–56.
-
(2013)
J Neurochem
, vol.127
, pp. 48-56
-
-
Laßek, M.1
Weingarten, J.2
Einsfelder, U.3
Brendel, P.4
Müller, U.5
Volknandt, W.6
-
122
-
-
70349256254
-
Repression of tau hyperphosphorylation by chronic endurance exercise in aged transgenic mouse model of tauopathies
-
Leem YH, Lim HJ, Shim SB, Cho JY, Kim BS, Han PL (2009) Repression of tau hyperphosphorylation by chronic endurance exercise in aged transgenic mouse model of tauopathies. J Neurosci Res 87:2561–2570.
-
(2009)
J Neurosci Res
, vol.87
, pp. 2561-2570
-
-
Leem, Y.H.1
Lim, H.J.2
Shim, S.B.3
Cho, J.Y.4
Kim, B.S.5
Han, P.L.6
-
123
-
-
84868127393
-
From mitochondrial dysfunction to amyloid beta formation: novel insights into the pathogenesis of Alzheimer's disease
-
Leuner K, Müller WE, Reichert AS (2012) From mitochondrial dysfunction to amyloid beta formation: novel insights into the pathogenesis of Alzheimer's disease. Mol Neurobiol 46:186–193.
-
(2012)
Mol Neurobiol
, vol.46
, pp. 186-193
-
-
Leuner, K.1
Müller, W.E.2
Reichert, A.S.3
-
124
-
-
84860198618
-
Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation
-
Leuner K, Schutt T, Kurz C, Eckert SH, Schiller C, Occhipinti A et al (2012) Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation. Antioxid Redox Signal 16:1421–1433.
-
(2012)
Antioxid Redox Signal
, vol.16
, pp. 1421-1433
-
-
Leuner, K.1
Schutt, T.2
Kurz, C.3
Eckert, S.H.4
Schiller, C.5
Occhipinti, A.6
-
125
-
-
0037081814
-
High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain
-
Lin MT, Simon DK, Ahn CH, Kim LM, Beal MF (2002) High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain. Hum Mol Genet 11:133–145.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 133-145
-
-
Lin, M.T.1
Simon, D.K.2
Ahn, C.H.3
Kim, L.M.4
Beal, M.F.5
-
126
-
-
16444382590
-
Gender differences in glutathione metabolism in Alzheimer's disease
-
Liu H, Harrell LE, Shenvi S, Hagen T, Liu RM (2005) Gender differences in glutathione metabolism in Alzheimer's disease. J Neurosci Res 79:861–867.
-
(2005)
J Neurosci Res
, vol.79
, pp. 861-867
-
-
Liu, H.1
Harrell, L.E.2
Shenvi, S.3
Hagen, T.4
Liu, R.M.5
-
127
-
-
84887194572
-
Physical activity and the brain: a review of this dynamic, bi-directional relationship
-
Loprinzi PD, Herod SM, Cardinal BJ, Noakes TD (2013) Physical activity and the brain: a review of this dynamic, bi-directional relationship. Brain Res 1539:95–104.
-
(2013)
Brain Res
, vol.1539
, pp. 95-104
-
-
Loprinzi, P.D.1
Herod, S.M.2
Cardinal, B.J.3
Noakes, T.D.4
-
128
-
-
11144353586
-
ABAD directly links Aß to mitochondrial toxicity in Alzheimer's Disease
-
Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N et al (2004) ABAD directly links Aß to mitochondrial toxicity in Alzheimer's Disease. Science 304:448–452.
-
(2004)
Science
, vol.304
, pp. 448-452
-
-
Lustbader, J.W.1
Cirilli, M.2
Lin, C.3
Xu, H.W.4
Takuma, K.5
Wang, N.6
-
129
-
-
84908246114
-
Axonal transport: cargo-specific mechanisms of motility and regulation
-
Maday S, Twelvetrees AE, Moughamian AJ, Holzbaur EL (2014) Axonal transport: cargo-specific mechanisms of motility and regulation. Neuron 84:292–309.
-
(2014)
Neuron
, vol.84
, pp. 292-309
-
-
Maday, S.1
Twelvetrees, A.E.2
Moughamian, A.J.3
Holzbaur, E.L.4
-
130
-
-
84930259783
-
A cellular perspective on brain energy metabolism and functional imaging
-
Magistretti PJ, Allaman I (2015) A cellular perspective on brain energy metabolism and functional imaging. Neuron 86:883–901.
-
(2015)
Neuron
, vol.86
, pp. 883-901
-
-
Magistretti, P.J.1
Allaman, I.2
-
131
-
-
33748757300
-
Mitochondrial dysfunction, oxidative stress and neurodegeneration
-
Mancuso M, Coppede F, Migliore L, Siciliano G, Murri L (2006) Mitochondrial dysfunction, oxidative stress and neurodegeneration. J Alzheimers Dis 10:59–73.
-
(2006)
J Alzheimers Dis
, vol.10
, pp. 59-73
-
-
Mancuso, M.1
Coppede, F.2
Migliore, L.3
Siciliano, G.4
Murri, L.5
-
132
-
-
33646152108
-
Mitochondria are a direct site of Aβ accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression
-
Manczak M, Anekonda TS, Henson E, Park BS, Quinn J, Reddy PH (2006) Mitochondria are a direct site of Aβ accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression. Hum Mol Genet 15:1437–1449.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1437-1449
-
-
Manczak, M.1
Anekonda, T.S.2
Henson, E.3
Park, B.S.4
Quinn, J.5
Reddy, P.H.6
-
133
-
-
79958721260
-
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage
-
Manczak M, Calkins MJ, Reddy PH (2011) Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage. Hum Mol Genet 20:2495–2509.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 2495-2509
-
-
Manczak, M.1
Calkins, M.J.2
Reddy, P.H.3
-
134
-
-
2342628596
-
Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage
-
Manczak M, Park BS, Jung Y, Reddy PH (2004) Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage. Neuromol Med 5:147–162.
-
(2004)
Neuromol Med
, vol.5
, pp. 147-162
-
-
Manczak, M.1
Park, B.S.2
Jung, Y.3
Reddy, P.H.4
-
135
-
-
84861130196
-
Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage
-
Manczak M, Reddy PH (2012) Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage. Hum Mol Genet 21:2538–2547.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 2538-2547
-
-
Manczak, M.1
Reddy, P.H.2
-
136
-
-
0345276565
-
Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses
-
Mandelkow E-M, Stamer K, Vogel R, Thies E, Mandelkow E (2003) Clogging of axons by tau, inhibition of axonal traffic and starvation of synapses. Neurobiol Aging 24:1079–1085.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 1079-1085
-
-
Mandelkow, E.-M.1
Stamer, K.2
Vogel, R.3
Thies, E.4
Mandelkow, E.5
-
137
-
-
84893021363
-
BDNF mediates adaptive brain and body responses to energetic challenges
-
Marosi K, Mattson MP (2014) BDNF mediates adaptive brain and body responses to energetic challenges. Trends Endocrinol Metab 25:89–98.
-
(2014)
Trends Endocrinol Metab
, vol.25
, pp. 89-98
-
-
Marosi, K.1
Mattson, M.P.2
-
138
-
-
84867896217
-
Physical exercise as a possible strategy for brain protection: evidence from mitochondrial-mediated mechanisms
-
Marques-Aleixo I, Oliveira PJ, Moreira PI, Magalhaes J, Ascensao A (2012) Physical exercise as a possible strategy for brain protection: evidence from mitochondrial-mediated mechanisms. Prog Neurobiol 99:149–162.
-
(2012)
Prog Neurobiol
, vol.99
, pp. 149-162
-
-
Marques-Aleixo, I.1
Oliveira, P.J.2
Moreira, P.I.3
Magalhaes, J.4
Ascensao, A.5
-
139
-
-
84947795323
-
Physical exercise improves brain cortex and cerebellum mitochondrial bioenergetics and alters apoptotic, dynamic and auto(mito)phagy markers
-
Marques-Aleixo I, Santos-Alves E, Balca MM, Rizo-Roca D, Moreira PI, Oliveira PJ et al (2015) Physical exercise improves brain cortex and cerebellum mitochondrial bioenergetics and alters apoptotic, dynamic and auto(mito)phagy markers. Neuroscience 301:480–495.
-
(2015)
Neuroscience
, vol.301
, pp. 480-495
-
-
Marques-Aleixo, I.1
Santos-Alves, E.2
Balca, M.M.3
Rizo-Roca, D.4
Moreira, P.I.5
Oliveira, P.J.6
-
140
-
-
84910599790
-
Physical exercise prior and during treatment reduces sub-chronic doxorubicin-induced mitochondrial toxicity and oxidative stress
-
Marques-Aleixo I, Santos-Alves E, Mariani D, Rizo-Roca D, Padrao AI, Rocha-Rodrigues S et al (2015) Physical exercise prior and during treatment reduces sub-chronic doxorubicin-induced mitochondrial toxicity and oxidative stress. Mitochondrion 20:22–33.
-
(2015)
Mitochondrion
, vol.20
, pp. 22-33
-
-
Marques-Aleixo, I.1
Santos-Alves, E.2
Mariani, D.3
Rizo-Roca, D.4
Padrao, A.I.5
Rocha-Rodrigues, S.6
-
141
-
-
85052358958
-
Exercise-induced protection against aging and neurodegenerative diseases: role of redox- and mitochondrial-based alterations
-
In, TFAA Farooqui, (ed), Wiley-Blackwell, New York
-
Marques-Aleixo IS-A,E, Moreira P, Oliveira P, Magalhães J, Ascensão A (2015) Exercise-induced protection against aging and neurodegenerative diseases: role of redox- and mitochondrial-based alterations. In: Diet and Exercise in Cognitive Function and Neurological Diseases. TFAA Farooqui (ed), pp. 3093–3022. Wiley-Blackwell: New York.
-
(2015)
Diet and Exercise in Cognitive Function and Neurological Diseases
, pp. 3022-3093
-
-
Marques-Aleixo, I.S.-A.1
Moreira, P.2
Oliveira, P.3
Magalhães, J.4
Ascensão, A.5
-
142
-
-
70450219539
-
Cholesterol metabolism and transport in the pathogenesis of Alzheimer's disease
-
Martins IJ, Berger T, Sharman MJ, Verdile G, Fuller SJ, Martins RN (2009) Cholesterol metabolism and transport in the pathogenesis of Alzheimer's disease. J Neurochem 111:1275–1308.
-
(2009)
J Neurochem
, vol.111
, pp. 1275-1308
-
-
Martins, I.J.1
Berger, T.2
Sharman, M.J.3
Verdile, G.4
Fuller, S.J.5
Martins, R.N.6
-
143
-
-
57049143140
-
Mitochondria in neuroplasticity and neurological disorders
-
Mattson MP, Gleichmann M, Cheng A (2008) Mitochondria in neuroplasticity and neurological disorders. Neuron 60:748–766.
-
(2008)
Neuron
, vol.60
, pp. 748-766
-
-
Mattson, M.P.1
Gleichmann, M.2
Cheng, A.3
-
144
-
-
0034612075
-
A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients
-
Maurer I, Zierz S, Moller HJ (2000) A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients. Neurobiol Aging 21:455–462.
-
(2000)
Neurobiol Aging
, vol.21
, pp. 455-462
-
-
Maurer, I.1
Zierz, S.2
Moller, H.J.3
-
145
-
-
38849150935
-
Mitochondrial oxidative stress causes hyperphosphorylation of tau
-
Melov S, Adlard PA, Morten K, Johnson F, Golden TR, Hinerfeld D et al (2007) Mitochondrial oxidative stress causes hyperphosphorylation of tau. PLoS One 2:e536.
-
(2007)
PLoS One
, vol.2
-
-
Melov, S.1
Adlard, P.A.2
Morten, K.3
Johnson, F.4
Golden, T.R.5
Hinerfeld, D.6
-
146
-
-
61649106707
-
Environmental-induced oxidative stress in neurodegenerative disorders and aging
-
Migliore L, Coppedè F (2009) Environmental-induced oxidative stress in neurodegenerative disorders and aging. Mutat Res/Genet Toxicol Environ Mutag 674:73–84.
-
(2009)
Mutat Res/Genet Toxicol Environ Mutag
, vol.674
, pp. 73-84
-
-
Migliore, L.1
Coppedè, F.2
-
147
-
-
0035828169
-
Identification of amyloid-β binding sites using an antisense peptide approach
-
Milton NG, Mayor NP, Rawlinson J (2001) Identification of amyloid-β binding sites using an antisense peptide approach. Neuroreport 12:2561–2566.
-
(2001)
Neuroreport
, vol.12
, pp. 2561-2566
-
-
Milton, N.G.1
Mayor, N.P.2
Rawlinson, J.3
-
148
-
-
0026683606
-
Differential distribution of cellular forms of β-amyloid precursor protein in murine glial cell cultures
-
Mizuguchi M, Ikeda K, Kim SU (1992) Differential distribution of cellular forms of β-amyloid precursor protein in murine glial cell cultures. Brain Res 584:219–225.
-
(1992)
Brain Res
, vol.584
, pp. 219-225
-
-
Mizuguchi, M.1
Ikeda, K.2
Kim, S.U.3
-
149
-
-
4644312270
-
Is intraneuronal amyloid beta-peptide accumulation the trigger of Alzheimer's disease pathophysiology?
-
discussion 43–439
-
Moreira PI, Liu Q, Honda K, Smith MA, Santos MS, Oliveira CR (2004) Is intraneuronal amyloid beta-peptide accumulation the trigger of Alzheimer's disease pathophysiology? J Alzheimers Dis 6:433–4; discussion 43–439.
-
(2004)
J Alzheimers Dis
, vol.6
, pp. 433-434
-
-
Moreira, P.I.1
Liu, Q.2
Honda, K.3
Smith, M.A.4
Santos, M.S.5
Oliveira, C.R.6
-
150
-
-
71849088759
-
Mitochondria: a therapeutic target in neurodegeneration
-
Moreira PI, Zhu X, Wang X, Lee H-G, Nunomura A, Petersen RB et al (2010) Mitochondria: a therapeutic target in neurodegeneration. Biochim Biophys Acta (BBA)-Mol Basis Dis 1802:212–220.
-
(2010)
Biochim Biophys Acta (BBA)-Mol Basis Dis
, vol.1802
, pp. 212-220
-
-
Moreira, P.I.1
Zhu, X.2
Wang, X.3
Lee, H.-G.4
Nunomura, A.5
Petersen, R.B.6
-
151
-
-
84903441756
-
Is Alzheimer's disease a systemic disease?
-
Morris JK, Honea RA, Vidoni ED, Swerdlow RH, Burns JM (2014) Is Alzheimer's disease a systemic disease? Biochim Biophys Acta 1842:1340–1349.
-
(2014)
Biochim Biophys Acta
, vol.1842
, pp. 1340-1349
-
-
Morris, J.K.1
Honea, R.A.2
Vidoni, E.D.3
Swerdlow, R.H.4
Burns, J.M.5
-
152
-
-
1342309919
-
Beneficial effects of moderate exercise on mice aging: survival, behavior, oxidative stress, and mitochondrial electron transfer
-
Navarro A, Gomez C, Lopez-Cepero JM, Boveris A (2004) Beneficial effects of moderate exercise on mice aging: survival, behavior, oxidative stress, and mitochondrial electron transfer. Am J Physiol Regul Integr Comp Physiol 286:R505–R511.
-
(2004)
Am J Physiol Regul Integr Comp Physiol
, vol.286
, pp. R505-R511
-
-
Navarro, A.1
Gomez, C.2
Lopez-Cepero, J.M.3
Boveris, A.4
-
154
-
-
34250705186
-
The mitochondrial permeability transition in neurologic disease
-
Norenberg MD, Rao KV (2007) The mitochondrial permeability transition in neurologic disease. Neurochem Int 50:983–997.
-
(2007)
Neurochem Int
, vol.50
, pp. 983-997
-
-
Norenberg, M.D.1
Rao, K.V.2
-
155
-
-
33747861696
-
Involvement of oxidative stress in Alzheimer disease
-
Nunomura A, Castellani RJ, Zhu X, Moreira PI, Perry G, Smith MA (2006) Involvement of oxidative stress in Alzheimer disease. J Neuropathol Exp Neurol 65:631–641.
-
(2006)
J Neuropathol Exp Neurol
, vol.65
, pp. 631-641
-
-
Nunomura, A.1
Castellani, R.J.2
Zhu, X.3
Moreira, P.I.4
Perry, G.5
Smith, M.A.6
-
156
-
-
0037730098
-
2-Methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency is caused by mutations in the HADH2 gene
-
Ofman R, Ruiter PJ, Feenstra M, Duran M, Poll-The TB, Zschocke J et al (2003) 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency is caused by mutations in the HADH2 gene. Am J Human Genet 72:1300–1307.
-
(2003)
Am J Human Genet
, vol.72
, pp. 1300-1307
-
-
Ofman, R.1
Ruiter, P.J.2
Feenstra, M.3
Duran, M.4
Poll-The, T.B.5
Zschocke, J.6
-
157
-
-
84866596476
-
Effects of physical exercise on cognitive alterations and oxidative stress in an APP/PSN1 transgenic model of Alzheimer's disease
-
Pareja-Galeano H, Brioche T, Sanchis-Gomar F, Escriva C, Dromant M, Gomez-Cabrera MC et al (2012) Effects of physical exercise on cognitive alterations and oxidative stress in an APP/PSN1 transgenic model of Alzheimer's disease. Rev Esp Geriatr Gerontol 47:198–204.
-
(2012)
Rev Esp Geriatr Gerontol
, vol.47
, pp. 198-204
-
-
Pareja-Galeano, H.1
Brioche, T.2
Sanchis-Gomar, F.3
Escriva, C.4
Dromant, M.5
Gomez-Cabrera, M.C.6
-
158
-
-
33845918450
-
β-Amyloid precursor protein is a direct cleavage target of htra2 serine protease implications for the physiological function of htra2 in the mitochondria
-
Park H-J, Kim S-S, Seong Y-M, Kim K-H, Goo HG, Yoon EJ et al (2006) β-Amyloid precursor protein is a direct cleavage target of htra2 serine protease implications for the physiological function of htra2 in the mitochondria. J Biol Chem 281:34277–34287.
-
(2006)
J Biol Chem
, vol.281
, pp. 34277-34287
-
-
Park, H.-J.1
Kim, S.-S.2
Seong, Y.-M.3
Kim, K.-H.4
Goo, H.G.5
Yoon, E.J.6
-
159
-
-
20044370830
-
The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which tau mediates β-amyloid-induced neurodegeneration
-
Park S-Y, Ferreira A (2005) The generation of a 17 kDa neurotoxic fragment: an alternative mechanism by which tau mediates β-amyloid-induced neurodegeneration. J Neurosci 25:5365–5375.
-
(2005)
J Neurosci
, vol.25
, pp. 5365-5375
-
-
Park, S.-Y.1
Ferreira, A.2
-
160
-
-
77449115085
-
Mitochondrial accumulation of APP and Aβ: significance for Alzheimer disease pathogenesis
-
Pavlov PF, Petersen CH, Glaser E, Ankarcrona M (2009) Mitochondrial accumulation of APP and Aβ: significance for Alzheimer disease pathogenesis. J Cell Mol Med 13:4137–4145.
-
(2009)
J Cell Mol Med
, vol.13
, pp. 4137-4145
-
-
Pavlov, P.F.1
Petersen, C.H.2
Glaser, E.3
Ankarcrona, M.4
-
161
-
-
79251584617
-
Mitochondrial γ-secretase participates in the metabolism of mitochondria-associated amyloid precursor protein
-
Pavlov PF, Wiehager B, Sakai J, Frykman S, Behbahani H, Winblad B et al (2011) Mitochondrial γ-secretase participates in the metabolism of mitochondria-associated amyloid precursor protein. FASEB J 25:78–88.
-
(2011)
FASEB J
, vol.25
, pp. 78-88
-
-
Pavlov, P.F.1
Wiehager, B.2
Sakai, J.3
Frykman, S.4
Behbahani, H.5
Winblad, B.6
-
162
-
-
84947443362
-
Protective effects of exercise in metabolic disorders are mediated by inhibition of mitochondrial-derived sterile inflammation
-
Peeri M, Amiri S (2015) Protective effects of exercise in metabolic disorders are mediated by inhibition of mitochondrial-derived sterile inflammation. Med Hypo 85:707–709.
-
(2015)
Med Hypo
, vol.85
, pp. 707-709
-
-
Peeri, M.1
Amiri, S.2
-
163
-
-
34248375311
-
An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus
-
Pereira AC, Huddleston DE, Brickman AM, Sosunov AA, Hen R, McKhann GM et al (2007) An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus. Proc Natl Acad Sci U S A 104:5638–5643.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 5638-5643
-
-
Pereira, A.C.1
Huddleston, D.E.2
Brickman, A.M.3
Sosunov, A.A.4
Hen, R.5
McKhann, G.M.6
-
164
-
-
0034237121
-
Oxidative damage in Alzheimer's disease: the metabolic dimension
-
Perry G, Nunomura A, Hirai K, Takeda A, Aliev G, Smith MA (2000) Oxidative damage in Alzheimer's disease: the metabolic dimension. Int J Dev Neurosci 18:417–421.
-
(2000)
Int J Dev Neurosci
, vol.18
, pp. 417-421
-
-
Perry, G.1
Nunomura, A.2
Hirai, K.3
Takeda, A.4
Aliev, G.5
Smith, M.A.6
-
165
-
-
51349110166
-
The amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae
-
Petersen CAH, Alikhani N, Behbahani H, Wiehager B, Pavlov PF, Alafuzoff I et al (2008) The amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae. Proc Natl Acad Sci 105:13145–13150.
-
(2008)
Proc Natl Acad Sci
, vol.105
, pp. 13145-13150
-
-
Petersen, C.A.H.1
Alikhani, N.2
Behbahani, H.3
Wiehager, B.4
Pavlov, P.F.5
Alafuzoff, I.6
-
166
-
-
34848917624
-
Mitochondrial effects of lipid-derived neurotoxins
-
Picklo MJ, Sr, Montine TJ (2007) Mitochondrial effects of lipid-derived neurotoxins. J Alzheimer's Dis 12:185–193.
-
(2007)
J Alzheimer's Dis
, vol.12
, pp. 185-193
-
-
Picklo, M.J.1
Montine, T.J.2
-
167
-
-
65249161745
-
Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta
-
Pigino G, Morfini G, Atagi Y, Deshpande A, Yu C, Jungbauer L et al (2009) Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta. Proc Natl Acad Sci U S A 106:5907–5912.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 5907-5912
-
-
Pigino, G.1
Morfini, G.2
Atagi, Y.3
Deshpande, A.4
Yu, C.5
Jungbauer, L.6
-
169
-
-
62449166389
-
PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia
-
Qin W, Haroutunian V, Katsel P, Cardozo CP, Ho L, Buxbaum JD et al (2009) PGC-1alpha expression decreases in the Alzheimer disease brain as a function of dementia. Arch Neurol 66:352–361.
-
(2009)
Arch Neurol
, vol.66
, pp. 352-361
-
-
Qin, W.1
Haroutunian, V.2
Katsel, P.3
Cardozo, C.P.4
Ho, L.5
Buxbaum, J.D.6
-
171
-
-
37849004479
-
Systemic adaptation to oxidative challenge induced by regular exercise
-
Radak Z, Chung HY, Goto S (2008) Systemic adaptation to oxidative challenge induced by regular exercise. Free Radic Biol Med 44:153–159.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 153-159
-
-
Radak, Z.1
Chung, H.Y.2
Goto, S.3
-
172
-
-
77954553684
-
Exercise plays a preventive role against Alzheimer's disease
-
Radak Z, Hart N, Sarga L, Koltai E, Atalay M, Ohno H et al (2010) Exercise plays a preventive role against Alzheimer's disease. J Alzheimers Dis 20:777–783.
-
(2010)
J Alzheimers Dis
, vol.20
, pp. 777-783
-
-
Radak, Z.1
Hart, N.2
Sarga, L.3
Koltai, E.4
Atalay, M.5
Ohno, H.6
-
173
-
-
36148961917
-
Effects of exercise on brain function: role of free radicals
-
Radak Z, Kumagai S, Taylor AW, Naito H, Goto S (2007) Effects of exercise on brain function: role of free radicals. Appl Physiol Nutr Metab 32:942–946.
-
(2007)
Appl Physiol Nutr Metab
, vol.32
, pp. 942-946
-
-
Radak, Z.1
Kumagai, S.2
Taylor, A.W.3
Naito, H.4
Goto, S.5
-
174
-
-
84887210624
-
The complex role of physical exercise and reactive oxygen species on brain
-
Radak Z, Marton O, Nagy E, Koltai E, Goto S (2013) The complex role of physical exercise and reactive oxygen species on brain. J Sport Health Sci 2:87–93.
-
(2013)
J Sport Health Sci
, vol.2
, pp. 87-93
-
-
Radak, Z.1
Marton, O.2
Nagy, E.3
Koltai, E.4
Goto, S.5
-
175
-
-
0034813092
-
Adaptation to exercise-induced oxidative stress: from muscle to brain
-
Radak Z, Taylor AW, Ohno H, Goto S (2001) Adaptation to exercise-induced oxidative stress: from muscle to brain. Exerc Immunol Rev 7:90–107.
-
(2001)
Exerc Immunol Rev
, vol.7
, pp. 90-107
-
-
Radak, Z.1
Taylor, A.W.2
Ohno, H.3
Goto, S.4
-
176
-
-
84873459937
-
Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signaling
-
Radak Z, Zhao Z, Koltai E, Ohno H, Atalay M (2013) Oxygen consumption and usage during physical exercise: the balance between oxidative stress and ROS-dependent adaptive signaling. Antioxid Redox Signal 18:1208–1246.
-
(2013)
Antioxid Redox Signal
, vol.18
, pp. 1208-1246
-
-
Radak, Z.1
Zhao, Z.2
Koltai, E.3
Ohno, H.4
Atalay, M.5
-
177
-
-
45149128904
-
Mitochondrial protein quality control by the proteasome involves ubiquitination and the protease Omi
-
Radke S, Chander H, Schäfer P, Meiss G, Krüger R, Schulz JB et al (2008) Mitochondrial protein quality control by the proteasome involves ubiquitination and the protease Omi. J Biol Chem 283:12681–12685.
-
(2008)
J Biol Chem
, vol.283
, pp. 12681-12685
-
-
Radke, S.1
Chander, H.2
Schäfer, P.3
Meiss, G.4
Krüger, R.5
Schulz, J.B.6
-
178
-
-
79958034614
-
The association between school-based physical activity, including physical education, and academic performance: a systematic review of the literature
-
Rasberry CN, Lee SM, Robin L, Laris BA, Russell LA, Coyle KK et al (2011) The association between school-based physical activity, including physical education, and academic performance: a systematic review of the literature. Prev Med 52 Suppl 1:S10–S20.
-
(2011)
Prev Med
, vol.52 Suppl 1
, pp. S10-S20
-
-
Rasberry, C.N.1
Lee, S.M.2
Robin, L.3
Laris, B.A.4
Russell, L.A.5
Coyle, K.K.6
-
179
-
-
79954573206
-
The positive impact of physical activity on cognition during adulthood: a review of underlying mechanisms, evidence and recommendations
-
Ratey JJ, Loehr JE (2011) The positive impact of physical activity on cognition during adulthood: a review of underlying mechanisms, evidence and recommendations. Rev Neurosci 22:171–185.
-
(2011)
Rev Neurosci
, vol.22
, pp. 171-185
-
-
Ratey, J.J.1
Loehr, J.E.2
-
180
-
-
77951226607
-
Beta-amyloid1-42 gene transfer model exhibits intraneuronal amyloid, gliosis, tau phosphorylation, and neuronal loss
-
Rebeck GW, Hoe HS, Moussa CE (2010) Beta-amyloid1-42 gene transfer model exhibits intraneuronal amyloid, gliosis, tau phosphorylation, and neuronal loss. J Biol Chem 285:7440–7446.
-
(2010)
J Biol Chem
, vol.285
, pp. 7440-7446
-
-
Rebeck, G.W.1
Hoe, H.S.2
Moussa, C.E.3
-
181
-
-
80052846665
-
Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease
-
Reddy PH (2011) Abnormal tau, mitochondrial dysfunction, impaired axonal transport of mitochondria, and synaptic deprivation in Alzheimer's disease. Brain Res 1415:136–148.
-
(2011)
Brain Res
, vol.1415
, pp. 136-148
-
-
Reddy, P.H.1
-
182
-
-
79957996565
-
Amyloid β-mediated cell death of cultured hippocampal neurons reveals extensive tau fragmentation without increased full-length tau phosphorylation
-
Reifert J, Hartung-Cranston D, Feinstein SC (2011) Amyloid β-mediated cell death of cultured hippocampal neurons reveals extensive tau fragmentation without increased full-length tau phosphorylation. J Biol Chem 286:20797–20811.
-
(2011)
J Biol Chem
, vol.286
, pp. 20797-20811
-
-
Reifert, J.1
Hartung-Cranston, D.2
Feinstein, S.C.3
-
183
-
-
84897954407
-
Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers
-
Reitz C, Mayeux R (2014) Alzheimer disease: epidemiology, diagnostic criteria, risk factors and biomarkers. Biochem Pharmacol 88:640–651.
-
(2014)
Biochem Pharmacol
, vol.88
, pp. 640-651
-
-
Reitz, C.1
Mayeux, R.2
-
184
-
-
43849096294
-
Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease
-
Resende R, Moreira PI, Proenca T, Deshpande A, Busciglio J, Pereira C et al (2008) Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease. Free Radic Biol Med 44:2051–2057.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 2051-2057
-
-
Resende, R.1
Moreira, P.I.2
Proenca, T.3
Deshpande, A.4
Busciglio, J.5
Pereira, C.6
-
185
-
-
73949142307
-
Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice
-
Rhein V, Song X, Wiesner A, Ittner LM, Baysang G, Meier F et al (2009) Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proc Natl Acad Sci 106:20057–20062.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 20057-20062
-
-
Rhein, V.1
Song, X.2
Wiesner, A.3
Ittner, L.M.4
Baysang, G.5
Meier, F.6
-
186
-
-
34447640166
-
The secreted β-amyloid precursor protein ectodomain APPsα is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice
-
Ring S, Weyer SW, Kilian SB, Waldron E, Pietrzik CU, Filippov MA et al (2007) The secreted β-amyloid precursor protein ectodomain APPsα is sufficient to rescue the anatomical, behavioral, and electrophysiological abnormalities of APP-deficient mice. J Neurosci 27:7817–7826.
-
(2007)
J Neurosci
, vol.27
, pp. 7817-7826
-
-
Ring, S.1
Weyer, S.W.2
Kilian, S.B.3
Waldron, E.4
Pietrzik, C.U.5
Filippov, M.A.6
-
187
-
-
0036968953
-
Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain
-
Rohn TT, Rissman RA, Davis MC, Kim YE, Cotman CW, Head E (2002) Caspase-9 activation and caspase cleavage of tau in the Alzheimer's disease brain. Neurobiol Dis 11:341–354.
-
(2002)
Neurobiol Dis
, vol.11
, pp. 341-354
-
-
Rohn, T.T.1
Rissman, R.A.2
Davis, M.C.3
Kim, Y.E.4
Cotman, C.W.5
Head, E.6
-
188
-
-
0030854715
-
Cellular energy utilization and molecular origin of standard metabolic rate in mammals
-
Rolfe DF, Brown GC (1997) Cellular energy utilization and molecular origin of standard metabolic rate in mammals. Physiol Rev 77:731–758.
-
(1997)
Physiol Rev
, vol.77
, pp. 731-758
-
-
Rolfe, D.F.1
Brown, G.C.2
-
189
-
-
0035954426
-
The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement
-
Sabo SL, Ikin AF, Buxbaum JD, Greengard P (2001) The Alzheimer amyloid precursor protein (APP) and FE65, an APP-binding protein, regulate cell movement. J Cell Biol 153:1403–1414.
-
(2001)
J Cell Biol
, vol.153
, pp. 1403-1414
-
-
Sabo, S.L.1
Ikin, A.F.2
Buxbaum, J.D.3
Greengard, P.4
-
190
-
-
82855169322
-
Emerging characterization of the role of SIRT3-mediated mitochondrial protein deacetylation in the heart
-
Sack MN (2011) Emerging characterization of the role of SIRT3-mediated mitochondrial protein deacetylation in the heart. Am J Physiol Heart Circ Physiol 301:H2191–H2197.
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.301
, pp. H2191-H2197
-
-
Sack, M.N.1
-
191
-
-
0034944055
-
Brain and liver mitochondria isolated from diabeticGoto-Kakizaki rats show different susceptibility to induced oxidative stress
-
Santos MS, Santos DL, Palmeira CM, Seiça R, Moreno AJ, Oliveira CR (2001) Brain and liver mitochondria isolated from diabeticGoto-Kakizaki rats show different susceptibility to induced oxidative stress. Diab/Metab Res Rev 17:223–230.
-
(2001)
Diab/Metab Res Rev
, vol.17
, pp. 223-230
-
-
Santos, M.S.1
Santos, D.L.2
Palmeira, C.M.3
Seiça, R.4
Moreno, A.J.5
Oliveira, C.R.6
-
192
-
-
84859230759
-
Tau's role in the developing brain: implications for intellectual disability
-
Sapir T, Frotscher M, Levy T, Mandelkow E-M, Reiner O (2012) Tau's role in the developing brain: implications for intellectual disability. Hum Mol Genet 21:1681–1692.
-
(2012)
Hum Mol Genet
, vol.21
, pp. 1681-1692
-
-
Sapir, T.1
Frotscher, M.2
Levy, T.3
Mandelkow, E.-M.4
Reiner, O.5
-
193
-
-
84860213834
-
Insights into mitochondrial dysfunction: aging, amyloid-β, and tau–a deleterious trio
-
Schmitt K, Grimm A, Kazmierczak A, Strosznajder JB, Götz J, Eckert A (2012) Insights into mitochondrial dysfunction: aging, amyloid-β, and tau–a deleterious trio. Antioxid Redox Signal 16:1456–1466.
-
(2012)
Antioxid Redox Signal
, vol.16
, pp. 1456-1466
-
-
Schmitt, K.1
Grimm, A.2
Kazmierczak, A.3
Strosznajder, J.B.4
Götz, J.5
Eckert, A.6
-
194
-
-
84911899819
-
Amyloid-β peptides are generated in mitochondria-associated endoplasmic reticulum membranes
-
Schreiner B, Hedskog L, Wiehager B, Ankarcrona M (2015) Amyloid-β peptides are generated in mitochondria-associated endoplasmic reticulum membranes. J Alzheimer's Dis 43:369–374.
-
(2015)
J Alzheimer's Dis
, vol.43
, pp. 369-374
-
-
Schreiner, B.1
Hedskog, L.2
Wiehager, B.3
Ankarcrona, M.4
-
195
-
-
11844272073
-
Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice
-
Schuessel K, Schafer S, Bayer TA, Czech C, Pradier L, Muller-Spahn F et al (2005) Impaired Cu/Zn-SOD activity contributes to increased oxidative damage in APP transgenic mice. Neurobiol Dis 18:89–99.
-
(2005)
Neurobiol Dis
, vol.18
, pp. 89-99
-
-
Schuessel, K.1
Schafer, S.2
Bayer, T.A.3
Czech, C.4
Pradier, L.5
Muller-Spahn, F.6
-
196
-
-
84894261400
-
Monitoring of neuronal loss in the hippocampus of Abeta-injected rat: autophagy, mitophagy, and mitochondrial biogenesis stand against apoptosis
-
Shaerzadeh F, Motamedi F, Minai-Tehrani D, Khodagholi F (2014) Monitoring of neuronal loss in the hippocampus of Abeta-injected rat: autophagy, mitophagy, and mitochondrial biogenesis stand against apoptosis. Neuromol Med 16:175–190.
-
(2014)
Neuromol Med
, vol.16
, pp. 175-190
-
-
Shaerzadeh, F.1
Motamedi, F.2
Minai-Tehrani, D.3
Khodagholi, F.4
-
197
-
-
84857073309
-
Regulation of mitochondrial transport and inter-microtubule spacing by tau phosphorylation at the sites hyperphosphorylated in Alzheimer's disease
-
Shahpasand K, Uemura I, Saito T, Asano T, Hata K, Shibata K et al (2012) Regulation of mitochondrial transport and inter-microtubule spacing by tau phosphorylation at the sites hyperphosphorylated in Alzheimer's disease. J Neurosci 32:2430–2441.
-
(2012)
J Neurosci
, vol.32
, pp. 2430-2441
-
-
Shahpasand, K.1
Uemura, I.2
Saito, T.3
Asano, T.4
Hata, K.5
Shibata, K.6
-
198
-
-
54949146482
-
Altered 8-oxoguanine glycosylase in mild cognitive impairment and late-stage Alzheimer's disease brain
-
Shao C, Xiong S, Li GM, Gu L, Mao G, Markesbery WR et al (2008) Altered 8-oxoguanine glycosylase in mild cognitive impairment and late-stage Alzheimer's disease brain. Free Radic Biol Med 45:813–819.
-
(2008)
Free Radic Biol Med
, vol.45
, pp. 813-819
-
-
Shao, C.1
Xiong, S.2
Li, G.M.3
Gu, L.4
Mao, G.5
Markesbery, W.R.6
-
199
-
-
84855687153
-
Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease
-
Sheng B, Wang X, Su B, Lee HG, Casadesus G, Perry G et al (2012) Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer's disease. J Neurochem 120:419–429.
-
(2012)
J Neurochem
, vol.120
, pp. 419-429
-
-
Sheng, B.1
Wang, X.2
Su, B.3
Lee, H.G.4
Casadesus, G.5
Perry, G.6
-
200
-
-
84856056846
-
Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration
-
Sheng Z-H, Cai Q (2012) Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration. Nat Rev Neurosci 13:77–93.
-
(2012)
Nat Rev Neurosci
, vol.13
, pp. 77-93
-
-
Sheng, Z.-H.1
Cai, Q.2
-
201
-
-
84892450175
-
Targeting neurogenesis ameliorates danger assessment in a mouse model of Alzheimer's disease
-
Shruster A, Offen D (2014) Targeting neurogenesis ameliorates danger assessment in a mouse model of Alzheimer's disease. Behav Brain Res 261:193–201.
-
(2014)
Behav Brain Res
, vol.261
, pp. 193-201
-
-
Shruster, A.1
Offen, D.2
-
202
-
-
79954662346
-
Effect of exercise on cognitive performance in community-dwelling older adults: review of intervention trials and recommendations for public health practice and research
-
Snowden M, Steinman L, Mochan K, Grodstein F, Prohaska TR, Thurman DJ et al (2011) Effect of exercise on cognitive performance in community-dwelling older adults: review of intervention trials and recommendations for public health practice and research. J Am Geriatr Soc 59:704–716.
-
(2011)
J Am Geriatr Soc
, vol.59
, pp. 704-716
-
-
Snowden, M.1
Steinman, L.2
Mochan, K.3
Grodstein, F.4
Prohaska, T.R.5
Thurman, D.J.6
-
203
-
-
0037128935
-
Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress
-
Stamer K, Vogel R, Thies E, Mandelkow E, Mandelkow E-M (2002) Tau blocks traffic of organelles, neurofilaments, and APP vesicles in neurons and enhances oxidative stress. J Cell Biol 156:1051–1063.
-
(2002)
J Cell Biol
, vol.156
, pp. 1051-1063
-
-
Stamer, K.1
Vogel, R.2
Thies, E.3
Mandelkow, E.4
Mandelkow, E.-M.5
-
204
-
-
58149220667
-
Cholesterol in Alzheimer's disease: unresolved questions
-
Stefani M, Liguri G (2009) Cholesterol in Alzheimer's disease: unresolved questions. Curr Alzheimer Res 6:15–29.
-
(2009)
Curr Alzheimer Res
, vol.6
, pp. 15-29
-
-
Stefani, M.1
Liguri, G.2
-
205
-
-
80054691291
-
Exercise training increases mitochondrial biogenesis in the brain
-
Steiner JL, Murphy EA, McClellan JL, Carmichael MD, Davis JM (2011) Exercise training increases mitochondrial biogenesis in the brain. J Appl Physiol (1985) 111:1066–1071.
-
(2011)
J Appl Physiol (1985)
, vol.111
, pp. 1066-1071
-
-
Steiner, J.L.1
Murphy, E.A.2
McClellan, J.L.3
Carmichael, M.D.4
Davis, J.M.5
-
206
-
-
84916892303
-
A cell model for the initial phase of sporadic Alzheimer's disease
-
Stockburger C, Gold VA, Pallas T, Kolesova N, Miano D, Leuner K et al (2014) A cell model for the initial phase of sporadic Alzheimer's disease. J Alzheimers Dis 42:395–411.
-
(2014)
J Alzheimers Dis
, vol.42
, pp. 395-411
-
-
Stockburger, C.1
Gold, V.A.2
Pallas, T.3
Kolesova, N.4
Miano, D.5
Leuner, K.6
-
207
-
-
70349319844
-
Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport
-
Stoothoff W, Jones PB, Spires-Jones TL, Joyner D, Chhabra E, Bercury K et al (2009) Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport. J Neurochem 111:417–427.
-
(2009)
J Neurochem
, vol.111
, pp. 417-427
-
-
Stoothoff, W.1
Jones, P.B.2
Spires-Jones, T.L.3
Joyner, D.4
Chhabra, E.5
Bercury, K.6
-
208
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
St-Pierre J, Drori S, Uldry M, Silvaggi JM, Rhee J, Jäger S et al (2006) Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 127:397–408.
-
(2006)
Cell
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
Jäger, S.6
-
209
-
-
84856521441
-
Anti-inflammatory effects of physical activity in relationship to improved cognitive status in humans and mouse models of Alzheimer's disease
-
Stranahan AM, Martin B, Maudsley S (2012) Anti-inflammatory effects of physical activity in relationship to improved cognitive status in humans and mouse models of Alzheimer's disease. Curr Alzheimer Res 9:86–92.
-
(2012)
Curr Alzheimer Res
, vol.9
, pp. 86-92
-
-
Stranahan, A.M.1
Martin, B.2
Maudsley, S.3
-
210
-
-
84892657154
-
Brain-derived neurotrophic factor (BDNF)-induced mitochondrial motility arrest and presynaptic docking contribute to BDNF-enhanced synaptic transmission
-
Su B, Ji YS, Sun XL, Liu XH, Chen ZY (2014) Brain-derived neurotrophic factor (BDNF)-induced mitochondrial motility arrest and presynaptic docking contribute to BDNF-enhanced synaptic transmission. J Biol Chem 289:1213–1226.
-
(2014)
J Biol Chem
, vol.289
, pp. 1213-1226
-
-
Su, B.1
Ji, Y.S.2
Sun, X.L.3
Liu, X.H.4
Chen, Z.Y.5
-
211
-
-
3042806534
-
A “mitochondrial cascade hypothesis” for sporadic Alzheimer's disease
-
Swerdlow RH, Khan SM (2004) A “mitochondrial cascade hypothesis” for sporadic Alzheimer's disease. Med Hypotheses 63:8–20.
-
(2004)
Med Hypotheses
, vol.63
, pp. 8-20
-
-
Swerdlow, R.H.1
Khan, S.M.2
-
212
-
-
73949088883
-
RAGE-mediated signaling contributes to intraneuronal transport of amyloid-β and neuronal dysfunction
-
Takuma K, Fang F, Zhang W, Yan S, Fukuzaki E, Du H et al (2009) RAGE-mediated signaling contributes to intraneuronal transport of amyloid-β and neuronal dysfunction. Proc Natl Acad Sci 106:20021–20026.
-
(2009)
Proc Natl Acad Sci
, vol.106
, pp. 20021-20026
-
-
Takuma, K.1
Fang, F.2
Zhang, W.3
Yan, S.4
Fukuzaki, E.5
Du, H.6
-
213
-
-
0030891028
-
Mitochondrial involvement in post-tetanic potentiation of synaptic transmission
-
Tang Y-G, Zucker RS (1997) Mitochondrial involvement in post-tetanic potentiation of synaptic transmission. Neuron 18:483–491.
-
(1997)
Neuron
, vol.18
, pp. 483-491
-
-
Tang, Y.-G.1
Zucker, R.S.2
-
214
-
-
79952315766
-
Influence of aging on membrane permeability transition in brain mitochondria
-
Toman J, Fiskum G (2011) Influence of aging on membrane permeability transition in brain mitochondria. J Bioenerg Biomembr 43:3–10.
-
(2011)
J Bioenerg Biomembr
, vol.43
, pp. 3-10
-
-
Toman, J.1
Fiskum, G.2
-
215
-
-
77950617631
-
A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo
-
Tomiyama T, Matsuyama S, Iso H, Umeda T, Takuma H, Ohnishi K et al (2010) A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo. J Neurosci 30:4845–4856.
-
(2010)
J Neurosci
, vol.30
, pp. 4845-4856
-
-
Tomiyama, T.1
Matsuyama, S.2
Iso, H.3
Umeda, T.4
Takuma, H.5
Ohnishi, K.6
-
216
-
-
84859197446
-
Does physical activity reduce risk for Alzheimer's disease through interaction with the stress neuroendocrine system?
-
Tortosa-Martinez J, Clow A (2012) Does physical activity reduce risk for Alzheimer's disease through interaction with the stress neuroendocrine system? Stress (Amsterdam, Netherlands) 15:243–261.
-
(2012)
Stress (Amsterdam, Netherlands)
, vol.15
, pp. 243-261
-
-
Tortosa-Martinez, J.1
Clow, A.2
-
217
-
-
0030969868
-
Superoxide production by the mitochondrial respiratory chain
-
Turrens JF (1997) Superoxide production by the mitochondrial respiratory chain. Biosci Rep 17:3–8.
-
(1997)
Biosci Rep
, vol.17
, pp. 3-8
-
-
Turrens, J.F.1
-
218
-
-
49349102894
-
Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view
-
Twig G, Hyde B, Shirihai OS (2008) Mitochondrial fusion, fission and autophagy as a quality control axis: the bioenergetic view. Biochim Biophys Acta (BBA)-Bioenerg 1777:1092–1097.
-
(2008)
Biochim Biophys Acta (BBA)-Bioenerg
, vol.1777
, pp. 1092-1097
-
-
Twig, G.1
Hyde, B.2
Shirihai, O.S.3
-
219
-
-
78650309919
-
Treadmill exercise represses neuronal cell death in an aged transgenic mouse model of Alzheimer's disease
-
Um HS, Kang EB, Koo JH, Kim HT, Jin L, Kim EJ et al (2011) Treadmill exercise represses neuronal cell death in an aged transgenic mouse model of Alzheimer's disease. Neurosci Res 69:161–173.
-
(2011)
Neurosci Res
, vol.69
, pp. 161-173
-
-
Um, H.S.1
Kang, E.B.2
Koo, J.H.3
Kim, H.T.4
Jin, L.5
Kim, E.J.6
-
220
-
-
54049126512
-
Exercise training acts as a therapeutic strategy for reduction of the pathogenic phenotypes for Alzheimer's disease in an NSE/APPsw-transgenic model
-
Um HS, Kang EB, Leem YH, Cho IH, Yang CH, Chae KR et al (2008) Exercise training acts as a therapeutic strategy for reduction of the pathogenic phenotypes for Alzheimer's disease in an NSE/APPsw-transgenic model. Int J Mol Med 22:529–539.
-
(2008)
Int J Mol Med
, vol.22
, pp. 529-539
-
-
Um, H.S.1
Kang, E.B.2
Leem, Y.H.3
Cho, I.H.4
Yang, C.H.5
Chae, K.R.6
-
221
-
-
84969443567
-
Intracellular amyloid beta oligomers impair organelle transport and induce dendritic spine loss in primary neurons
-
Umeda T, Ramser EM, Yamashita M, Nakajima K, Mori H, Silverman MA et al (2015) Intracellular amyloid beta oligomers impair organelle transport and induce dendritic spine loss in primary neurons. Acta Neuropathol Commun 3:51.
-
(2015)
Acta Neuropathol Commun
, vol.3
, pp. 51
-
-
Umeda, T.1
Ramser, E.M.2
Yamashita, M.3
Nakajima, K.4
Mori, H.5
Silverman, M.A.6
-
222
-
-
79955601720
-
Intraneuronal amyloid beta oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo
-
Umeda T, Tomiyama T, Sakama N, Tanaka S, Lambert MP, Klein WL et al (2011) Intraneuronal amyloid beta oligomers cause cell death via endoplasmic reticulum stress, endosomal/lysosomal leakage, and mitochondrial dysfunction in vivo. J Neurosci Res 89:1031–1042.
-
(2011)
J Neurosci Res
, vol.89
, pp. 1031-1042
-
-
Umeda, T.1
Tomiyama, T.2
Sakama, N.3
Tanaka, S.4
Lambert, M.P.5
Klein, W.L.6
-
223
-
-
5444236916
-
Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1
-
Varadi A, Johnson-Cadwell LI, Cirulli V, Yoon Y, Allan VJ, Rutter GA (2004) Cytoplasmic dynein regulates the subcellular distribution of mitochondria by controlling the recruitment of the fission factor dynamin-related protein-1. J Cell Sci 117:4389–4400.
-
(2004)
J Cell Sci
, vol.117
, pp. 4389-4400
-
-
Varadi, A.1
Johnson-Cadwell, L.I.2
Cirulli, V.3
Yoon, Y.4
Allan, V.J.5
Rutter, G.A.6
-
224
-
-
33846118789
-
Multiple-motor based transport and its regulation by Tau
-
Vershinin M, Carter BC, Razafsky DS, King SJ, Gross SP (2007) Multiple-motor based transport and its regulation by Tau. Proc Natl Acad Sci U S A 104:87–92.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 87-92
-
-
Vershinin, M.1
Carter, B.C.2
Razafsky, D.S.3
King, S.J.4
Gross, S.P.5
-
225
-
-
84903717860
-
Pharmacological properties of physical exercise in the elderly
-
Vina J, Borras C, Sanchis-Gomar F, Martinez-Bello VE, Olaso-Gonzalez G, Gambini J et al (2014) Pharmacological properties of physical exercise in the elderly. Curr Pharm Des 20:3019–3029.
-
(2014)
Curr Pharm Des
, vol.20
, pp. 3019-3029
-
-
Vina, J.1
Borras, C.2
Sanchis-Gomar, F.3
Martinez-Bello, V.E.4
Olaso-Gonzalez, G.5
Gambini, J.6
-
226
-
-
71549134294
-
Mitochondrial biogenesis in exercise and in ageing
-
Vina J, Gomez-Cabrera MC, Borras C, Froio T, Sanchis-Gomar F, Martinez-Bello VE et al (2009) Mitochondrial biogenesis in exercise and in ageing. Adv Drug Deliv Rev 61:1369–1374.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 1369-1374
-
-
Vina, J.1
Gomez-Cabrera, M.C.2
Borras, C.3
Froio, T.4
Sanchis-Gomar, F.5
Martinez-Bello, V.E.6
-
227
-
-
0031470093
-
Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice
-
Von Koch C, Zheng H, Chen H, Trumbauer M, Thinakaran G, Van der Ploeg L et al (1997) Generation of APLP2 KO mice and early postnatal lethality in APLP2/APP double KO mice. Neurobiol Aging 18:661–669.
-
(1997)
Neurobiol Aging
, vol.18
, pp. 661-669
-
-
Von Koch, C.1
Zheng, H.2
Chen, H.3
Trumbauer, M.4
Thinakaran, G.5
Van der Ploeg, L.6
-
228
-
-
43249124363
-
Microtubule-associated protein tau in development, degeneration and protection of neurons
-
Wang J-Z, Liu F (2008) Microtubule-associated protein tau in development, degeneration and protection of neurons. Prog Neurobiol 85:148–175.
-
(2008)
Prog Neurobiol
, vol.85
, pp. 148-175
-
-
Wang, J.-Z.1
Liu, F.2
-
229
-
-
84884933900
-
Voluntary exercise counteracts Abeta25-35-induced memory impairment in mice
-
Wang Q, Xu Z, Tang J, Sun J, Gao J, Wu T et al (2013) Voluntary exercise counteracts Abeta25-35-induced memory impairment in mice. Behav Brain Res 256:618–625.
-
(2013)
Behav Brain Res
, vol.256
, pp. 618-625
-
-
Wang, Q.1
Xu, Z.2
Tang, J.3
Sun, J.4
Gao, J.5
Wu, T.6
-
230
-
-
48749085779
-
Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients
-
Wang X, Su B, Fujioka H, Zhu X (2008) Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients. Am J Pathol 173:470–482.
-
(2008)
Am J Pathol
, vol.173
, pp. 470-482
-
-
Wang, X.1
Su, B.2
Fujioka, H.3
Zhu, X.4
-
231
-
-
67650732998
-
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease
-
Wang X, Su B, Lee H-g, Li X, Perry G, Smith MA et al (2009) Impaired balance of mitochondrial fission and fusion in Alzheimer's disease. J Neurosci 29:9090–9103.
-
(2009)
J Neurosci
, vol.29
, pp. 9090-9103
-
-
Wang, X.1
Su, B.2
Lee, H.-G.3
Li, X.4
Perry, G.5
Smith, M.A.6
-
232
-
-
58049218922
-
Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins
-
Wang X, Su B, Siedlak SL, Moreira PI, Fujioka H, Wang Y et al (2008) Amyloid-beta overproduction causes abnormal mitochondrial dynamics via differential modulation of mitochondrial fission/fusion proteins. Proc Natl Acad Sci U S A 105:19318–19323.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 19318-19323
-
-
Wang, X.1
Su, B.2
Siedlak, S.L.3
Moreira, P.I.4
Fujioka, H.5
Wang, Y.6
-
233
-
-
84903304059
-
Oxidative stress and mitochondrial dysfunction in Alzheimer's disease
-
Wang X, Wang W, Li L, Perry G, Lee H-g, Zhu X (2014) Oxidative stress and mitochondrial dysfunction in Alzheimer's disease. Biochim Biophys Acta (BBA)-Mol Basis Dis 1842:1240–1247.
-
(2014)
Biochim Biophys Acta (BBA)-Mol Basis Dis
, vol.1842
, pp. 1240-1247
-
-
Wang, X.1
Wang, W.2
Li, L.3
Perry, G.4
Lee, H.-G.5
Zhu, X.6
-
234
-
-
78649413837
-
Mitochondrial fusion and fission in cell life and death
-
Westermann B (2010) Mitochondrial fusion and fission in cell life and death. Nat Rev Mol Cell Biol 11:872–884.
-
(2010)
Nat Rev Mol Cell Biol
, vol.11
, pp. 872-884
-
-
Westermann, B.1
-
235
-
-
0035933279
-
Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice
-
Wirths O, Multhaup G, Czech C, Blanchard V, Moussaoui S, Tremp G et al (2001) Intraneuronal Abeta accumulation precedes plaque formation in beta-amyloid precursor protein and presenilin-1 double-transgenic mice. Neurosci Lett 306:116–120.
-
(2001)
Neurosci Lett
, vol.306
, pp. 116-120
-
-
Wirths, O.1
Multhaup, G.2
Czech, C.3
Blanchard, V.4
Moussaoui, S.5
Tremp, G.6
-
236
-
-
0028859466
-
Regulated formation of Golgi secretory vesicles containing Alzheimer β-amyloid precursor protein
-
Xu H, Greengard P, Gandy S (1995) Regulated formation of Golgi secretory vesicles containing Alzheimer β-amyloid precursor protein. J Biol Chem 270:23243–23245.
-
(1995)
J Biol Chem
, vol.270
, pp. 23243-23245
-
-
Xu, H.1
Greengard, P.2
Gandy, S.3
-
237
-
-
84884816645
-
Aerobic exercise combined with antioxidative treatment does not counteract moderate- or mid-stage Alzheimer-like pathophysiology of APP/PS1 mice
-
Xu ZQ, Zhang LQ, Wang Q, Marshall C, Xiao N, Gao JY et al (2013) Aerobic exercise combined with antioxidative treatment does not counteract moderate- or mid-stage Alzheimer-like pathophysiology of APP/PS1 mice. CNS Neurosci Ther 19:795–803.
-
(2013)
CNS Neurosci Ther
, vol.19
, pp. 795-803
-
-
Xu, Z.Q.1
Zhang, L.Q.2
Wang, Q.3
Marshall, C.4
Xiao, N.5
Gao, J.Y.6
-
238
-
-
20444441575
-
Mitochondrial dysfunction and Alzheimer's disease: role of amyloid-beta peptide alcohol dehydrogenase (ABAD)
-
Yan SD, Stern DM (2005) Mitochondrial dysfunction and Alzheimer's disease: role of amyloid-beta peptide alcohol dehydrogenase (ABAD). Int J Exp Pathol 86:161–171.
-
(2005)
Int J Exp Pathol
, vol.86
, pp. 161-171
-
-
Yan, S.D.1
Stern, D.M.2
-
239
-
-
33847051684
-
Surface plasmon resonance and nuclear magnetic resonance studies of ABAD-Aβ interaction
-
Yan Y, Liu Y, Sorci M, Belfort G, Lustbader JW, Yan SS et al (2007) Surface plasmon resonance and nuclear magnetic resonance studies of ABAD-Aβ interaction. Biochemistry 46:1724–1731.
-
(2007)
Biochemistry
, vol.46
, pp. 1724-1731
-
-
Yan, Y.1
Liu, Y.2
Sorci, M.3
Belfort, G.4
Lustbader, J.W.5
Yan, S.S.6
-
240
-
-
84939260692
-
Mitochondrial Sirt3 Expression is Decreased in APP/PS1 Double Transgenic Mouse Model of Alzheimer's Disease
-
Yang W, Zou Y, Zhang M, Zhao N, Tian Q, Gu M et al (2015) Mitochondrial Sirt3 Expression is Decreased in APP/PS1 Double Transgenic Mouse Model of Alzheimer's Disease. Neurochem Res 40:1576–1582.
-
(2015)
Neurochem Res
, vol.40
, pp. 1576-1582
-
-
Yang, W.1
Zou, Y.2
Zhang, M.3
Zhao, N.4
Tian, Q.5
Gu, M.6
-
241
-
-
70149093436
-
Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
-
Yao J, Irwin RW, Zhao L, Nilsen J, Hamilton RT, Brinton RD (2009) Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 106:14670–14675.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14670-14675
-
-
Yao, J.1
Irwin, R.W.2
Zhao, L.3
Nilsen, J.4
Hamilton, R.T.5
Brinton, R.D.6
-
243
-
-
84891787701
-
Mitochondrial energy metabolism and redox signaling in brain aging and neurodegeneration
-
Yin F, Boveris A, Cadenas E (2014) Mitochondrial energy metabolism and redox signaling in brain aging and neurodegeneration. Antioxid Redox Signal 20:353–371.
-
(2014)
Antioxid Redox Signal
, vol.20
, pp. 353-371
-
-
Yin, F.1
Boveris, A.2
Cadenas, E.3
|