-
1
-
-
79960325654
-
The toxicity of tau in Alzheimer disease: Turnover, targets and potential therapeutics
-
S. M. Pritchard, P. J. Dolan, A. Vitkus, and G. V. W. Johnson, "The toxicity of tau in Alzheimer disease: turnover, targets and potential therapeutics, " Journal of Cellular and Molecular Medicine, vol. 15, no. 8, pp. 1621-1635, 2011.
-
(2011)
Journal of Cellular and Molecular Medicine
, vol.15
, Issue.8
, pp. 1621-1635
-
-
Pritchard, S.M.1
Dolan, P.J.2
Vitkus, A.3
Johnson, G.V.W.4
-
2
-
-
84858046578
-
Neuropathological alterations in Alzheimer disease
-
A. Serrano-Pozo, M. P. Frosch, E. Masliah, and B. T. Hyman, "Neuropathological alterations in Alzheimer disease, " Cold Spring Harbor Perspectives in Medicine, vol. 1, no. 1, Article ID a006189, 23 pages, 2011.
-
(2011)
Cold Spring Harbor Perspectives in Medicine
, vol.1
, Issue.1
-
-
Serrano-Pozo, A.1
Frosch, M.P.2
Masliah, E.3
Hyman, B.T.4
-
3
-
-
84929657432
-
Clinicopathologic and 11C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer's disease spectrum
-
M. E. Murray, V. J. Lowe, N. R. Graff-Radford et al., "Clinicopathologic and 11C-Pittsburgh compound B implications of Thal amyloid phase across the Alzheimer's disease spectrum, " Brain, vol. 138, no. 5, pp. 1370-1381, 2015.
-
(2015)
Brain
, vol.138
, Issue.5
, pp. 1370-1381
-
-
Murray, M.E.1
Lowe, V.J.2
Graff-Radford, N.R.3
-
4
-
-
81455157378
-
Mitochondrial dysfunction - The beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity
-
A. Eckert, K. Schmitt, and J. Götz, "Mitochondrial dysfunction - the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity, " Alzheimer's Research and Therapy, vol. 3, no. 3, article 15, 2011.
-
(2011)
Alzheimer's Research and Therapy
, vol.3
, Issue.3
-
-
Eckert, A.1
Schmitt, K.2
Götz, J.3
-
5
-
-
84865187620
-
Mitochondrial dysfunction in neurodegenerative diseases
-
A. Johri andM. F. Beal, "Mitochondrial dysfunction in neurodegenerative diseases, " Journal of Pharmacology and Experimental Therapeutics, vol. 342, no. 3, pp. 619-630, 2012.
-
(2012)
Journal of Pharmacology and Experimental Therapeutics
, vol.342
, Issue.3
, pp. 619-630
-
-
Johri, A.1
Beal, M.F.2
-
6
-
-
84878586555
-
Why size matters-balancing mitochondrial dynamics in Alzheimer's disease
-
B. DuBoff, M. Feany, and J.Götz, "Why size matters-balancing mitochondrial dynamics in Alzheimer's disease, " Trends in Neurosciences, vol. 36, no. 6, pp. 325-335, 2013.
-
(2013)
Trends in Neurosciences
, vol.36
, Issue.6
, pp. 325-335
-
-
Duboff, B.1
Feany, M.2
Götz, J.3
-
7
-
-
84879853173
-
Principles of the mitochondrial fusion and fission cycle in neurons
-
M. Cagalinec, D. Safiulina, M. Liiv et al., "Principles of the mitochondrial fusion and fission cycle in neurons, " Journal of Cell Science, vol. 126, no. 10, pp. 2187-2197, 2013.
-
(2013)
Journal of Cell Science
, vol.126
, Issue.10
, pp. 2187-2197
-
-
Cagalinec, M.1
Safiulina, D.2
Liiv, M.3
-
9
-
-
36248957122
-
Mechanisms of Aβ mediated neurodegeneration in Alzheimer's disease
-
P. J. Crouch, S. M. E. Harding, A. R. White, J. Camakaris, A. I. Bush, and C. L. Masters, "Mechanisms of Aβ mediated neurodegeneration in Alzheimer's disease, " International Journal of Biochemistry & Cell Biology, vol. 40, no. 2, pp. 181-198, 2008.
-
(2008)
International Journal of Biochemistry & Cell Biology
, vol.40
, Issue.2
, pp. 181-198
-
-
Crouch, P.J.1
Harding, S.M.E.2
White, A.R.3
Camakaris, J.4
Bush, A.I.5
Masters, C.L.6
-
10
-
-
4544235673
-
Calcium, ATP, and ROS: A mitochondrial love-hate triangle
-
P. S. Brookes, Y. Yoon, J. L. Robotham, M. W. Anders, and S.-S. Sheu, "Calcium, ATP, and ROS: a mitochondrial love-hate triangle, " American Journal of Physiology - Cell Physiology, vol. 287, no. 4, pp. C817-C833, 2004.
-
(2004)
American Journal of Physiology - Cell Physiology
, vol.287
, Issue.4
, pp. C817-C833
-
-
Brookes, P.S.1
Yoon, Y.2
Robotham, J.L.3
Anders, M.W.4
Sheu, S.-S.5
-
11
-
-
84897567836
-
Mitochondrial trafficking and anchoring in neurons: New insight and implications
-
Z.-H. Sheng, "Mitochondrial trafficking and anchoring in neurons: new insight and implications, " Journal of Cell Biology, vol. 204, no. 7, pp. 1087-1098, 2014.
-
(2014)
Journal of Cell Biology
, vol.204
, Issue.7
, pp. 1087-1098
-
-
Sheng, Z.-H.1
-
13
-
-
84936994657
-
Axonal transport defects in Alzheimer's disease
-
Z.-X.Wang, L. Tan, and J.-T. Yu, "Axonal transport defects in Alzheimer's disease, " Molecular Neurobiology, vol. 51, no. 3, pp. 1309-1321, 2015.
-
(2015)
Molecular Neurobiology
, vol.51
, Issue.3
, pp. 1309-1321
-
-
Wang, Z.-X.1
Tan, L.2
Yu, J.-T.3
-
14
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
G. Twig, A. Elorza, A. J. A. Molina et al., "Fission and selective fusion govern mitochondrial segregation and elimination by autophagy, "TheEMBOJournal, vol. 27, no. 2, pp.433-446, 2008.
-
(2008)
TheEMBOJournal
, vol.27
, Issue.2
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
Molina, A.J.A.3
-
15
-
-
33745274726
-
Mitochondria: Dynamic organelles in disease, aging, and development
-
D. C. Chan, "Mitochondria: dynamic organelles in disease, aging, and development, " Cell, vol. 125, no. 7, pp. 1241-1252, 2006.
-
(2006)
Cell
, vol.125
, Issue.7
, pp. 1241-1252
-
-
Chan, D.C.1
-
16
-
-
84899637375
-
Mitochondrial morphological features are associated with fission and fusion events
-
L. M. Westrate, J. A. Drocco, K. R. Martin, W. S. Hlavacek, and J. P.MacKeigan, "Mitochondrial morphological features are associated with fission and fusion events, " PLoS ONE, vol. 9, no. 4, Article ID e95265, 15 pages, 2014.
-
(2014)
PLoS ONE
, vol.9
, Issue.4
-
-
Westrate, L.M.1
Drocco, J.A.2
Martin, K.R.3
Hlavacek, W.S.4
Mackeigan, J.P.5
-
17
-
-
84864061186
-
Deceleration of fusion-fission cycles improves mitochondrial quality control during aging
-
M. T. Figge, A. S. Reichert, M. Meyer-Hermann, and H. D. Osiewacz, "Deceleration of fusion-fission cycles improves mitochondrial quality control during aging, " PLoS Computational Biology, vol. 8, no. 6, Article ID e1002576, 18 pages, 2012.
-
(2012)
PLoS Computational Biology
, vol.8
, Issue.6
-
-
Figge, M.T.1
Reichert, A.S.2
Meyer-Hermann, M.3
Osiewacz, H.D.4
-
18
-
-
67650868959
-
Mitochondrial dynamics in mammalian health and disease
-
M. Liesa, M. Palacín, andA. Zorzano, "Mitochondrial dynamics in mammalian health and disease, " Physiological Reviews, vol. 89, no. 3, pp. 799-845, 2009.
-
(2009)
Physiological Reviews
, vol.89
, Issue.3
, pp. 799-845
-
-
Liesa, M.1
Palacín, M.2
Zorzano, A.3
-
19
-
-
84865544952
-
Mitochondrial fission, fusion, and stress
-
R. J. Youle and A. M. van der Bliek, "Mitochondrial fission, fusion, and stress, " Science, vol. 337, no. 6098, pp. 1062-1065, 2012.
-
(2012)
Science
, vol.337
, Issue.6098
, pp. 1062-1065
-
-
Youle, R.J.1
Bliek Der Van, A.M.2
-
20
-
-
77951096150
-
Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
-
H. Chen and D. C. Chan, "Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases, " HumanMolecular Genetics, vol. 18, no. 2, pp.R169-R176, 2009.
-
(2009)
HumanMolecular Genetics
, vol.18
, Issue.2
, pp. R169-R176
-
-
Chen, H.1
Chan, D.C.2
-
21
-
-
79957937433
-
Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases
-
P. H. Reddy, T. P. Reddy, M. Manczak, M. J. Calkins, U. Shirendeb, and P.Mao, "Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases, " Brain Research Reviews, vol. 67, no. 1-2, pp. 103-118, 2011.
-
(2011)
Brain Research Reviews
, vol.67
, Issue.1-2
, pp. 103-118
-
-
Reddy, P.H.1
Reddy, T.P.2
Manczak, M.3
Calkins, M.J.4
Shirendeb, U.5
Mao, P.6
-
22
-
-
25444471534
-
Dnm1 forms spirals that are structurally tailored to fit mitochondria
-
E. Ingerman, E. M. Perkins, M. Marino et al., "Dnm1 forms spirals that are structurally tailored to fit mitochondria, " The Journal of Cell Biology, vol. 170, no. 7, pp. 1021-1027, 2005.
-
(2005)
The Journal of Cell Biology
, vol.170
, Issue.7
, pp. 1021-1027
-
-
Ingerman, E.1
Perkins, E.M.2
Marino, M.3
-
23
-
-
36749075083
-
Structural basis for recruitment of mitochondrial fission complexes by Fis1
-
Y. Zhang and D. C. Chan, "Structural basis for recruitment of mitochondrial fission complexes by Fis1, " Proceedings of the National Academy of Sciences of the United States of America, vol. 104, no. 47, pp. 18526-18530, 2007.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.47
, pp. 18526-18530
-
-
Zhang, Y.1
Chan, D.C.2
-
24
-
-
84874639591
-
Fis1, Mff, MiD49, andMiD51 mediateDrp1 recruitment in mitochondrial fission
-
O. C. Losón, Z. Song, H. Chen, and D. C. Chan, "Fis1, Mff, MiD49, andMiD51 mediateDrp1 recruitment in mitochondrial fission, "Molecular Biology of the Cell, vol. 24, no. 5, pp. 659-667, 2013.
-
(2013)
Molecular Biology of the Cell
, vol.24
, Issue.5
, pp. 659-667
-
-
Losón, O.C.1
Song, Z.2
Chen, H.3
Chan, D.C.4
-
25
-
-
27744491193
-
Emerging functions of mammalian mitochondrial fusion and fission
-
H. Chen and D. C. Chan, "Emerging functions of mammalian mitochondrial fusion and fission, " Human Molecular Genetics, vol. 14, no. 2, pp. R283-R289, 2005.
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.2
, pp. R283-R289
-
-
Chen, H.1
Chan, D.C.2
-
26
-
-
68149103297
-
Mitofusins and OPA1 mediate sequential steps in mitochondrialmembrane fusion
-
Z. Song, M. Ghochani, J. M. McCaffery, T. G. Frey, and D. C. Chan, "Mitofusins and OPA1 mediate sequential steps in mitochondrialmembrane fusion, "Molecular Biology of the Cell, vol. 20, no. 15, pp. 3525-3532, 2009.
-
(2009)
Molecular Biology of the Cell
, vol.20
, Issue.15
, pp. 3525-3532
-
-
Song, Z.1
Ghochani, M.2
McCaffery, J.M.3
Frey, T.G.4
Chan, D.C.5
-
27
-
-
79960729178
-
The regulation of mitochondrial morphology: Intricate mechanisms and dynamic machinery
-
C. S. Palmer, L. D. Osellame, D. Stojanovski, and M. T. Ryan, "The regulation of mitochondrial morphology: intricate mechanisms and dynamic machinery, " Cellular Signalling, vol. 23, no. 10, pp. 1534-1545, 2011.
-
(2011)
Cellular Signalling
, vol.23
, Issue.10
, pp. 1534-1545
-
-
Palmer, C.S.1
Osellame, L.D.2
Stojanovski, D.3
Ryan, M.T.4
-
28
-
-
84884527459
-
Dominant optic atrophy, OPA1, and mitochondrial quality control: Understanding mitochondrial network dynamics
-
M. V. Alavi and N. Fuhrmann, "Dominant optic atrophy, OPA1, and mitochondrial quality control: understanding mitochondrial network dynamics, " Molecular Neurodegeneration, vol. 8, article 32, 2013.
-
(2013)
Molecular Neurodegeneration
, vol.8
-
-
Alavi, M.V.1
Fuhrmann, N.2
-
29
-
-
34547601410
-
Mitochondrial fusion protects against neurodegeneration in the cerebellum
-
H. Chen, J. M. McCaffery, and D. C. Chan, "Mitochondrial fusion protects against neurodegeneration in the cerebellum, " Cell, vol. 130, no. 3, pp. 548-562, 2007.
-
(2007)
Cell
, vol.130
, Issue.3
, pp. 548-562
-
-
Chen, H.1
McCaffery, J.M.2
Chan, D.C.3
-
30
-
-
67650732998
-
Impaired balance of mitochondrial fission and fusion in Alzheimer's disease
-
X.Wang, B. Su, H.-G. Lee et al., "Impaired balance of mitochondrial fission and fusion in Alzheimer's disease, " The Journal of Neuroscience, vol. 29, no. 28, pp. 9090-9103, 2009.
-
(2009)
The Journal of Neuroscience
, vol.29
, Issue.28
, pp. 9090-9103
-
-
Wang, X.1
Su, B.2
Lee, H.-G.3
-
31
-
-
84889650334
-
Inflammation-induced alteration of astrocyte mitochondrial dynamics requires autophagy for mitochondrial network maintenance
-
E.Motori, J. Puyal, N. Toni et al., "Inflammation-induced alteration of astrocyte mitochondrial dynamics requires autophagy for mitochondrial network maintenance, " Cell Metabolism, vol. 18, no. 6, pp. 844-859, 2013.
-
(2013)
Cell Metabolism
, vol.18
, Issue.6
, pp. 844-859
-
-
Motori, E.1
Puyal, J.2
Toni, N.3
-
32
-
-
24144438228
-
Differentiated Alzheimer's disease transmitochondrial cybrid cell lines exhibit reduced organelle movement
-
P. A. Trimmer and M. K. Borland, "Differentiated Alzheimer's disease transmitochondrial cybrid cell lines exhibit reduced organelle movement, " Antioxidants and Redox Signaling, vol. 7, no. 9-10, pp. 1101-1109, 2005.
-
(2005)
Antioxidants and Redox Signaling
, vol.7
, Issue.9-10
, pp. 1101-1109
-
-
Trimmer, P.A.1
Borland, M.K.2
-
33
-
-
58049218922
-
Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation ofmitochondrial fission/fusion proteins
-
X.Wang, B. Su, S. L. Siedlak et al., "Amyloid-β overproduction causes abnormal mitochondrial dynamics via differential modulation ofmitochondrial fission/fusion proteins, " Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 49, pp. 19318-19323, 2008.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.49
, pp. 19318-19323
-
-
Wang, X.1
Su, B.2
Siedlak, S.L.3
-
34
-
-
78649815388
-
Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model
-
H.Du, L. Guo, S. Yan, A. A. Sosunov, G. M. McKhann, and S. S. Yan, "Early deficits in synaptic mitochondria in an Alzheimer's disease mouse model, " Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 43, pp. 18670-18675, 2010.
-
(2010)
Proceedings of the National Academy of Sciences of the United States of America
, vol.107
, Issue.43
, pp. 18670-18675
-
-
Du, H.1
Guo, L.2
Yan, S.3
Sosunov, A.A.4
McKhann, G.M.5
Yan, S.S.6
-
35
-
-
84891906038
-
Presynaptic mitochondrial morphology in monkey prefrontal cortex correlates with working memory and is improved with estrogen treatment
-
Y. Hara, F. Yuk, R. Puri, W. G. M. Janssen, P. R. Rapp, and J. H. Morrison, "Presynaptic mitochondrial morphology in monkey prefrontal cortex correlates with working memory and is improved with estrogen treatment, " Proceedings of the National Academy of Sciences of the United States of America, vol. 111, no. 1, pp. 486-491, 2014.
-
(2014)
Proceedings of the National Academy of Sciences of the United States of America
, vol.111
, Issue.1
, pp. 486-491
-
-
Hara, Y.1
Yuk, F.2
Puri, R.3
Janssen, W.G.M.4
Rapp, P.R.5
Morrison, J.H.6
-
36
-
-
79958721260
-
Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: Implications for neuronal damage
-
M. Manczak, M. J. Calkins, and P. H. Reddy, "Impaired mitochondrial dynamics and abnormal interaction of amyloid beta with mitochondrial protein Drp1 in neurons from patients with Alzheimer's disease: implications for neuronal damage, " Human Molecular Genetics, vol. 20, no. 13, Article ID ddr139, pp. 2495-2509, 2011.
-
(2011)
Human Molecular Genetics
, vol.20
, Issue.13
, pp. 2495-2509
-
-
Manczak, M.1
Calkins, M.J.2
Reddy, P.H.3
-
37
-
-
77955322042
-
Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models
-
L.M. Ittner, Y. D. Ke, F.Delerue et al., "Dendritic function of tau mediates amyloid-beta toxicity in Alzheimer's disease mouse models, " Cell, vol. 142, no. 3, pp. 387-397, 2010.
-
(2010)
Cell
, vol.142
, Issue.3
, pp. 387-397
-
-
Ittner, L.M.1
Ke, Y.D.2
Delerue, F.3
-
38
-
-
84911496555
-
Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death
-
A. Martorell-Riera, M. Segarra-Mondejar, J. P. Muñoz et al., "Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death, " The EMBO Journal, vol. 33, no. 20, pp. 2388-2407, 2014.
-
(2014)
The EMBO Journal
, vol.33
, Issue.20
, pp. 2388-2407
-
-
Martorell-Riera, A.1
Segarra-Mondejar, M.2
Muñoz, J.P.3
-
39
-
-
84924571507
-
Loss of mitofusin 2 links betaamyloid-mediated mitochondrial fragmentation and Cdk5-induced oxidative stress in neuron cells
-
J. Park, H. Choi, J.-S.Min et al., "Loss of mitofusin 2 links betaamyloid-mediated mitochondrial fragmentation and Cdk5-induced oxidative stress in neuron cells, " Journal of Neurochemistry, vol. 132, no. 6, pp. 687-702, 2015.
-
(2015)
Journal of Neurochemistry
, vol.132
, Issue.6
, pp. 687-702
-
-
Park, J.1
Choi, H.2
Min, J.-S.3
-
40
-
-
33646152108
-
Mitochondria are a direct site of Abeta accumulation in Alzheimer's disease neurons: Implications for free radical generation and oxidative damage in disease progression
-
M. Manczak, T. S. Anekonda, E. Henson, B. S. Park, J. Quinn, and P. H. Reddy, "Mitochondria are a direct site of Abeta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression, " HumanMolecular Genetics, vol. 15, no. 9, pp. 1437-1449, 2006.
-
(2006)
HumanMolecular Genetics
, vol.15
, Issue.9
, pp. 1437-1449
-
-
Manczak, M.1
Anekonda, T.S.2
Henson, E.3
Park, B.S.4
Quinn, J.5
Reddy, P.H.6
-
41
-
-
51349110166
-
The amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae
-
C. A. H. Petersen, N. Alikhani, H. Behbahani et al., "The amyloid β-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae, " Proceedings of the National Academy of Sciences of the United States of America, vol. 105, no. 35, pp. 13145-13150, 2008.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, Issue.35
, pp. 13145-13150
-
-
Petersen, C.A.H.1
Alikhani, N.2
Behbahani, H.3
-
42
-
-
11144228296
-
Glycogen synthase kinase 3β induces caspase-cleaved tau aggregation in situ
-
J.-H. Cho and G. V. W. Johnson, "Glycogen synthase kinase 3β induces caspase-cleaved tau aggregation in situ, " The Journal of Biological Chemistry, vol. 279, no. 52, pp. 54716-54723, 2004.
-
(2004)
The Journal of Biological Chemistry
, vol.279
, Issue.52
, pp. 54716-54723
-
-
Cho, J.-H.1
Johnson, G.V.W.2
-
43
-
-
84867028061
-
Caspase-mediated truncation of Tau potentiates aggregation
-
S. Lee and T. B. Shea, "Caspase-mediated truncation of Tau potentiates aggregation, " International Journal of Alzheimer's Disease, vol. 2012, Article ID 731063, 7 pages, 2012.
-
(2012)
International Journal of Alzheimer's Disease
, vol.2012
-
-
Lee, S.1
Shea, T.B.2
-
44
-
-
20044385920
-
Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease
-
G. B. Stokin, C. Lillo, T. L. Falzone et al., "Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease, " Science, vol. 307, no. 5713, pp. 1282-1288, 2005.
-
(2005)
Science
, vol.307
, Issue.5713
, pp. 1282-1288
-
-
Stokin, G.B.1
Lillo, C.2
Falzone, T.L.3
-
45
-
-
45349094984
-
Mitochondrial dynamics and apoptosis
-
D.-F. Suen, K. L. Norris, and R. J. Youle, "Mitochondrial dynamics and apoptosis, " Genes & Development, vol. 22, no. 12, pp. 1577-1590, 2008.
-
(2008)
Genes & Development
, vol.22
, Issue.12
, pp. 1577-1590
-
-
Suen, D.-F.1
Norris, K.L.2
Youle, R.J.3
-
46
-
-
67650556426
-
Caspase-cleaved tau expression induces mitochondrial dysfunction in immortalized cortical neurons: Implications for the pathogenesis of Alzheimer disease
-
R. A. Quintanilla, T. A. Matthews-Roberson, P. J. Dolan, and G. V. W. Johnsion, "Caspase-cleaved tau expression induces mitochondrial dysfunction in immortalized cortical neurons: implications for the pathogenesis of Alzheimer disease, " The Journal of Biological Chemistry, vol. 284, no. 28, pp. 18754-18766, 2009.
-
(2009)
The Journal of Biological Chemistry
, vol.284
, Issue.28
, pp. 18754-18766
-
-
Quintanilla, R.A.1
Matthews-Roberson, T.A.2
Dolan, P.J.3
Johnsion, G.V.W.4
-
47
-
-
84855761078
-
Truncated tau and Aβ cooperatively impair mitochondria in primary neurons
-
R. A. Quintanilla, P. J. Dolan, Y. N. Jin, and G. V. W. Johnson, "Truncated tau and Aβ cooperatively impair mitochondria in primary neurons, " Neurobiology of Aging, vol. 33, no. 3, pp. 619.e25-619.e35, 2012.
-
(2012)
Neurobiology of Aging
, vol.33
, Issue.3
, pp. 619e25-619e35
-
-
Quintanilla, R.A.1
Dolan, P.J.2
Jin, Y.N.3
Johnson, G.V.W.4
-
48
-
-
84861130196
-
Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: Implications for mitochondrial dysfunction and neuronal damage
-
M. Manczak and P. H. Reddy, "Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage, " Human Molecular Genetics, vol. 21, no. 11, pp. 2538-2547, 2012.
-
(2012)
Human Molecular Genetics
, vol.21
, Issue.11
, pp. 2538-2547
-
-
Manczak, M.1
Reddy, P.H.2
-
49
-
-
84908210642
-
Phosphorylated tau potentiates Aβ-induced mitochondrial damage in mature neurons
-
R.A.Quintanilla, R. vonBernhardi, J. A.Godoy, N. C. Inestrosa, and G. V. W. Johnson, "Phosphorylated tau potentiates Aβ-induced mitochondrial damage in mature neurons, " Neurobiology of Disease, vol. 71, no. 1, pp. 260-269, 2014.
-
(2014)
Neurobiology of Disease
, vol.71
, Issue.1
, pp. 260-269
-
-
Quintanilla, R.A.1
Vonbernhardi, R.2
Godoy, J.A.3
Inestrosa, N.C.4
Johnson, G.V.W.5
-
50
-
-
18244390483
-
Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications
-
P.Bubber, V. Haroutunian, G. Fisch, J. P. Blass, andG.E.Gibson, "Mitochondrial abnormalities in Alzheimer brain: mechanistic implications, " Annals of Neurology, vol. 57, no. 5, pp. 695-703, 2005.
-
(2005)
Annals of Neurology
, vol.57
, Issue.5
, pp. 695-703
-
-
Bubber, P.1
Haroutunian, V.2
Fisch, G.3
Blass, J.P.4
Gibson, G.E.5
-
51
-
-
68949152521
-
Brain mitochondria as a primary target in the development of treatment strategies for Alzheimer disease
-
G. Aliev, H. H. Palacios, B. Walrafen, A. E. Lipsitt, M. E. Obrenovich, and L.Morales, "Brain mitochondria as a primary target in the development of treatment strategies for Alzheimer disease, " The International Journal of Biochemistry & Cell Biology, vol. 41, no. 10, pp. 1989-2004, 2009.
-
(2009)
The International Journal of Biochemistry & Cell Biology
, vol.41
, Issue.10
, pp. 1989-2004
-
-
Aliev, G.1
Palacios, H.H.2
Walrafen, B.3
Lipsitt, A.E.4
Obrenovich, M.E.5
Morales, L.6
-
52
-
-
69249211284
-
Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice
-
S.Hauptmann, I. Scherping, S. Dröse et al., "Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice, " Neurobiology of Aging, vol. 30, no. 10, pp. 1574-1586, 2009.
-
(2009)
Neurobiology of Aging
, vol.30
, Issue.10
, pp. 1574-1586
-
-
Hauptmann, S.1
Scherping, I.2
Dröse, S.3
-
53
-
-
73949142307
-
Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice
-
V. Rhein, X. Song, A. Wiesner et al., "Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice, " Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 47, pp. 20057-20062, 2009.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.47
, pp. 20057-20062
-
-
Rhein, V.1
Song, X.2
Wiesner, A.3
-
54
-
-
0022619098
-
Positron emission tomography in Alzheimer's disease
-
R. Duara, C. Grady, J. Haxby et al., "Positron emission tomography in Alzheimer's disease, " Neurology, vol. 36, no. 7, pp. 879-887, 1986.
-
(1986)
Neurology
, vol.36
, Issue.7
, pp. 879-887
-
-
Duara, R.1
Grady, C.2
Haxby, J.3
-
55
-
-
80052538857
-
Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: Implications for early intervention and therapeutics
-
P. Mao and P. H. Reddy, "Aging and amyloid beta-induced oxidative DNA damage and mitochondrial dysfunction in Alzheimer's disease: implications for early intervention and therapeutics, " Biochimica et Biophysica Acta, vol. 1812, no. 11, pp. 1359-1370, 2011.
-
(2011)
Biochimica et Biophysica Acta
, vol.1812
, Issue.11
, pp. 1359-1370
-
-
Mao, P.1
Reddy, P.H.2
-
56
-
-
0036272650
-
β-Amyloid inhibits integrated mitochondrial respiration and key enzyme activities
-
C. S. Casley, L. Canevari, J. M. Land, J. B. Clark, and M. A. Sharpe, "β-amyloid inhibits integrated mitochondrial respiration and key enzyme activities, " Journal of Neurochemistry, vol. 80, no. 1, pp. 91-100, 2002.
-
(2002)
Journal of Neurochemistry
, vol.80
, Issue.1
, pp. 91-100
-
-
Casley, C.S.1
Canevari, L.2
Land, J.M.3
Clark, J.B.4
Sharpe, M.A.5
-
57
-
-
19944433571
-
Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-β1-42
-
P. J. Crouch, R. Blake, J. A.Duce et al., "Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-β1-42, " Journal of Neuroscience, vol. 25, no. 3, pp. 672-679, 2005.
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.3
, pp. 672-679
-
-
Crouch, P.J.1
Blake, R.2
Duce, J.A.3
-
58
-
-
0036403832
-
β-Amyloid fragment 25-35 causes mitochondrial dysfunction in primary cortical neurons
-
C. S.Casley, J.M. Land, M.A. Sharpe, J. B. Clark, M. R. Duchen, and L. Canevari, "β-Amyloid fragment 25-35 causes mitochondrial dysfunction in primary cortical neurons, " Neurobiology of Disease, vol. 10, no. 3, pp. 258-267, 2002.
-
(2002)
Neurobiology of Disease
, vol.10
, Issue.3
, pp. 258-267
-
-
Casley, C.S.1
Land, J.M.2
Sharpe, M.A.3
Clark, J.B.4
Duchen, M.R.5
Canevari, L.6
-
59
-
-
0034745636
-
Neurotoxic Aβ peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxidesynthase mechanisms, and inhibit complex IV activity and induce amitochondrial permeability transition in vitro
-
J. K. Parks, T. S. Smith, P. A. Trimmer, J. P. Bennett Jr., and W. D. Parker Jr., "Neurotoxic Aβ peptides increase oxidative stress in vivo through NMDA-receptor and nitric-oxidesynthase mechanisms, and inhibit complex IV activity and induce amitochondrial permeability transition in vitro, " Journal of Neurochemistry, vol. 76, no. 4, pp. 1050-1056, 2001.
-
(2001)
Journal of Neurochemistry
, vol.76
, Issue.4
, pp. 1050-1056
-
-
Parks, J.K.1
Smith, T.S.2
Trimmer, P.A.3
Bennett, J.P.4
Parker, W.D.5
-
60
-
-
26444588771
-
Gradual alteration of mitochondrial structure and function by β-amyloids: Importance ofmembrane viscosity changes, energy deprivation, reactive oxygen species production, and cytochrome c release
-
A. M. Aleardi, G. Benard, O. Augereau et al., "Gradual alteration of mitochondrial structure and function by β-amyloids: importance ofmembrane viscosity changes, energy deprivation, reactive oxygen species production, and cytochrome c release, " Journal of Bioenergetics and Biomembranes, vol. 37, no. 4, pp. 207-225, 2005.
-
(2005)
Journal of Bioenergetics and Biomembranes
, vol.37
, Issue.4
, pp. 207-225
-
-
Aleardi, A.M.1
Benard, G.2
Augereau, O.3
-
61
-
-
0037192392
-
Induction of cytochrome c-mediated apoptosis by amyloid β 25-35 requires functionalmitochondria
-
S. M. Cardoso, R. H. Swerdlow, and C. R. Oliveira, "Induction of cytochrome c-mediated apoptosis by amyloid β 25-35 requires functionalmitochondria, " Brain Research, vol. 931, no.2, pp. 117-125, 2002.
-
(2002)
Brain Research
, vol.931
, Issue.2
, pp. 117-125
-
-
Cardoso, S.M.1
Swerdlow, R.H.2
Oliveira, C.R.3
-
62
-
-
19444383084
-
Abeta(31-35) and Abeta(25-35) fragments of amyloid beta-protein induce cellular death through apoptotic signals: Role of the redox state of methionine-35
-
M.E.Clementi, S.Marini, M. Coletta, F.Orsini, B.Giardina, and F.Misiti, "Abeta(31-35) and Abeta(25-35) fragments of amyloid beta-protein induce cellular death through apoptotic signals: role of the redox state of methionine-35, " FEBS Letters, vol. 579, no. 13, pp. 2913-2918, 2005.
-
(2005)
FEBS Letters
, vol.579
, Issue.13
, pp. 2913-2918
-
-
Clementi, M.E.1
Marini, S.2
Coletta, M.3
Orsini, F.4
Giardina, B.5
Misiti, F.6
-
63
-
-
84860198618
-
Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation
-
K. Leuner, T. Schütt, C. Kurz et al., "Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation, " Antioxidants & Redox Signaling, vol. 16, no. 12, pp. 1421-1433, 2012.
-
(2012)
Antioxidants & Redox Signaling
, vol.16
, Issue.12
, pp. 1421-1433
-
-
Leuner, K.1
Schütt, T.2
Kurz, C.3
-
64
-
-
84886925692
-
Mitochondrial alterations near amyloid plaques in an Alzheimer's disease mouse model
-
H. Xie, J. Guan, L. A. Borrelli, J. Xu, A. Serrano-Pozo, and B. J. Bacskai, "Mitochondrial alterations near amyloid plaques in an Alzheimer's disease mouse model, " The Journal of Neuroscience, vol. 33, no. 43, pp. 17042-17051, 2013.
-
(2013)
The Journal of Neuroscience
, vol.33
, Issue.43
, pp. 17042-17051
-
-
Xie, H.1
Guan, J.2
Borrelli, L.A.3
Xu, J.4
Serrano-Pozo, A.5
Bacskai, B.J.6
-
65
-
-
84863245760
-
Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress inmousemodels of familial Alzheimer's disease
-
E. Trushina, E. Nemutlu, S. Zhang et al., "Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress inmousemodels of familial alzheimer's disease, " PLoS ONE, vol. 7, no. 2, Article ID e32737, 17 pages, 2012.
-
(2012)
PLoS ONE
, vol.7
, Issue.2
-
-
Trushina, E.1
Nemutlu, E.2
Zhang, S.3
-
66
-
-
84871658247
-
Understanding risk factors for Alzheimer's disease: Interplay of neuroinflammation, connexin-based communication and oxidative stress
-
R. A. Quintanilla, J. A. Orellana, and R. von Bernhardi, "Understanding risk factors for Alzheimer's disease: interplay of neuroinflammation, connexin-based communication and oxidative stress, " Archives ofMedical Research, vol. 43, no. 8, pp. 632-644, 2012.
-
(2012)
Archives OfMedical Research
, vol.43
, Issue.8
, pp. 632-644
-
-
Quintanilla, R.A.1
Orellana, J.A.2
Von Bernhardi, R.3
-
67
-
-
33746238205
-
Molecular indices of oxidative stress and mitochondrial dysfunction occur early and often progress with severity of Alzheimer's disease
-
S. M. de la Monte and J. R. Wands, "Molecular indices of oxidative stress and mitochondrial dysfunction occur early and often progress with severity of Alzheimer's disease, " Journal of Alzheimer's Disease, vol. 9, no. 2, pp. 167-181, 2006.
-
(2006)
Journal of Alzheimer's Disease
, vol.9
, Issue.2
, pp. 167-181
-
-
De La Monte, S.M.1
Wands, J.R.2
-
68
-
-
70149093436
-
Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
-
J. Yao, R. W. Irwin, L. Zhao, J. Nilsen, R. T. Hamilton, and R. D. Brinton, "Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease, " Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 34, pp. 14670-14675, 2009.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.34
, pp. 14670-14675
-
-
Yao, J.1
Irwin, R.W.2
Zhao, L.3
Nilsen, J.4
Hamilton, R.T.5
Brinton, R.D.6
-
69
-
-
21244486781
-
Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice
-
D. C. David, S. Hauptmann, I. Scherping et al., "Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice, "The Journal of Biological Chemistry, vol. 280, no. 25, pp. 23802-23814, 2005.
-
(2005)
The Journal of Biological Chemistry
, vol.280
, Issue.25
, pp. 23802-23814
-
-
David, D.C.1
Hauptmann, S.2
Scherping, I.3
-
70
-
-
84862870271
-
The axonal transport of mitochondria
-
W. M. Saxton and P. J. Hollenbeck, "The axonal transport of mitochondria, " Journal of Cell Science, vol. 125, no. 9, pp. 2095-2104, 2012.
-
(2012)
Journal of Cell Science
, vol.125
, Issue.9
, pp. 2095-2104
-
-
Saxton, W.M.1
Hollenbeck, P.J.2
-
71
-
-
33749398995
-
The genetics of axonal transport and axonal transport disorders
-
J. E. Duncan and L. S. B. Goldstein, "The genetics of axonal transport and axonal transport disorders, " PLoS Genetics, vol. 2, no. 9, pp. 1275-1284, 2006.
-
(2006)
PLoS Genetics
, vol.2
, Issue.9
, pp. 1275-1284
-
-
Duncan, J.E.1
Goldstein, L.S.B.2
-
72
-
-
84901441806
-
Shaping the dynamic mitochondrial network
-
L. L. Lackner, "Shaping the dynamic mitochondrial network, " BMC Biology, vol. 12, no. 1, article 35, 2014.
-
(2014)
BMC Biology
, vol.12
, Issue.1
-
-
Lackner, L.L.1
-
73
-
-
84875443717
-
Axonal transport deficits and neurodegenerative diseases
-
S. Millecamps and J.-P. Julien, "Axonal transport deficits and neurodegenerative diseases, " Nature Reviews Neuroscience, vol. 14, no. 3, pp. 161-176, 2013.
-
(2013)
Nature Reviews Neuroscience
, vol.14
, Issue.3
, pp. 161-176
-
-
Millecamps, S.1
Julien, J.-P.2
-
74
-
-
84856056846
-
Mitochondrial transport in neurons: Impact on synaptic homeostasis and neurodegeneration
-
Z. H. Sheng and Q. Cai, "Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration, " Nature Reviews Neuroscience, vol. 13, no. 2, pp. 77-93, 2012.
-
(2012)
Nature Reviews Neuroscience
, vol.13
, Issue.2
, pp. 77-93
-
-
Sheng, Z.H.1
Cai, Q.2
-
75
-
-
84929269425
-
Regulation of mitochondrial transport in neurons
-
M. Y. Lin and Z. H. Sheng, "Regulation of mitochondrial transport in neurons, " Experimental Cell Research, vol. 334, no. 1, pp. 35-44, 2015.
-
(2015)
Experimental Cell Research
, vol.334
, Issue.1
, pp. 35-44
-
-
Lin, M.Y.1
Sheng, Z.H.2
-
76
-
-
84880806405
-
Kinesin-1-syntaphilin coupling mediates activity-dependent regulation of axonal mitochondrial transport
-
Y. Chen and Z.-H. Sheng, "Kinesin-1-syntaphilin coupling mediates activity-dependent regulation of axonal mitochondrial transport, " The Journal of Cell Biology, vol. 202, no. 2, pp. 351-364, 2013.
-
(2013)
The Journal of Cell Biology
, vol.202
, Issue.2
, pp. 351-364
-
-
Chen, Y.1
Sheng, Z.-H.2
-
77
-
-
39449138356
-
Tau inhibits anterograde axonal transport and perturbs stability in growing axonal neurites in part by displacing kinesin cargo: Neurofilaments attenuate tau-mediated neurite instability
-
M. Dubey, P. Chaudhury, H. Kabiru, and T. B. Shea, "Tau inhibits anterograde axonal transport and perturbs stability in growing axonal neurites in part by displacing kinesin cargo: neurofilaments attenuate tau-mediated neurite instability, " Cell Motility and the Cytoskeleton, vol. 65, no. 2, pp. 89-99, 2008.
-
(2008)
Cell Motility and the Cytoskeleton
, vol.65
, Issue.2
, pp. 89-99
-
-
Dubey, M.1
Chaudhury, P.2
Kabiru, H.3
Shea, T.B.4
-
78
-
-
84866150232
-
Loss of axonal mitochondria promotes tau-mediated neurodegeneration and Alzheimer's disease-related tau phosphorylation via PAR-1
-
K. Iijima-Ando, M. Sekiya, A. Maruko-Otake et al., "Loss of axonal mitochondria promotes tau-mediated neurodegeneration and Alzheimer's disease-related tau phosphorylation via PAR-1, " PLoS Genetics, vol. 8, no. 8, Article ID e1002918, 2012.
-
(2012)
PLoS Genetics
, vol.8
, Issue.8
-
-
Iijima-Ando, K.1
Sekiya, M.2
Maruko-Otake, A.3
-
79
-
-
80052846665
-
Abnormal tau, mitochondrial dysfunction, impaired axonal transport ofmitochondria, and synaptic deprivation in Alzheimer's disease
-
P. H. Reddy, "Abnormal tau, mitochondrial dysfunction, impaired axonal transport ofmitochondria, and synaptic deprivation in Alzheimer's disease, " Brain Research, vol. 1415, pp. 136-148, 2011.
-
(2011)
Brain Research
, vol.1415
, pp. 136-148
-
-
Reddy, P.H.1
-
80
-
-
79751537405
-
Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons
-
M. J. Calkins and P. H. Reddy, "Amyloid beta impairs mitochondrial anterograde transport and degenerates synapses in Alzheimer's disease neurons, " Biochimica et BiophysicaActa, vol. 1812, no. 4, pp. 507-513, 2011.
-
(2011)
Biochimica et BiophysicaActa
, vol.1812
, Issue.4
, pp. 507-513
-
-
Calkins, M.J.1
Reddy, P.H.2
-
81
-
-
77957737750
-
Tau reduction prevents Aβ-induced defects in axonal transport
-
K. A. Vossel, K. Zhang, J. Brodbeck et al., "Tau reduction prevents Aβ-induced defects in axonal transport, " Science, vol. 330, no. 6001, p. 198, 2010.
-
(2010)
Science
, vol.330
, Issue.6001
, pp. 198
-
-
Vossel, K.A.1
Zhang, K.2
Brodbeck, J.3
-
82
-
-
84936998627
-
Tau reductionprevents Aβ-induced axonal transport deficits by blocking activation of GSK3
-
K.A.Vossel, J. C. Xu, V.Fomenko et al., "Tau reductionprevents Aβ-induced axonal transport deficits by blocking activation of GSK3, " The Journal of Cell Biology, vol. 209, no. 3, pp. 419-433, 2015.
-
(2015)
The Journal of Cell Biology
, vol.209
, Issue.3
, pp. 419-433
-
-
Vossel, K.A.1
Xu, J.C.2
Fomenko, V.3
-
83
-
-
84873130522
-
Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neurons
-
L. Guo, H. Du, S. Yan et al., "Cyclophilin D deficiency rescues axonal mitochondrial transport in Alzheimer's neurons, " PLoS ONE, vol. 8, no. 1, Article ID e54914, 13 pages, 2013.
-
(2013)
PLoS ONE
, vol.8
, Issue.1
-
-
Guo, L.1
Du, H.2
Yan, S.3
-
84
-
-
81255190781
-
Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease
-
M. J. Calkins, M. Manczak, P. Mao, U. Shirendeb, and P. H. Reddy, "Impaired mitochondrial biogenesis, defective axonal transport of mitochondria, abnormal mitochondrial dynamics and synaptic degeneration in a mouse model of Alzheimer's disease, " Human Molecular Genetics, vol. 20, no. 23, pp. 4515-4529, 2011.
-
(2011)
Human Molecular Genetics
, vol.20
, Issue.23
, pp. 4515-4529
-
-
Calkins, M.J.1
Manczak, M.2
Mao, P.3
Shirendeb, U.4
Reddy, P.H.5
-
85
-
-
81055124828
-
GSK3β is involved in the relief of mitochondria pausing in a Tau-dependent manner
-
M. Llorens-Martín, G. López-Doménech, E. Soriano, and J. Avila, "GSK3β is involved in the relief of mitochondria pausing in a Tau-dependent manner, " PLoS ONE, vol. 6, no. 11, Article ID e27686, 8 pages, 2011.
-
(2011)
PLoS ONE
, vol.6
, Issue.11
-
-
Llorens-Martín, M.1
López-Doménech, G.2
Soriano, E.3
Avila, J.4
-
86
-
-
84857073309
-
Regulation of mitochondrial transport and inter-microtubule spacing by tau phosphorylation at the sites hyperphosphorylated in Alzheimer's disease
-
K. Shahpasand, I. Uemura, T. Saito et al., "Regulation of mitochondrial transport and inter-microtubule spacing by tau phosphorylation at the sites hyperphosphorylated in Alzheimer's disease, " The Journal of Neuroscience, vol. 32, no. 7, pp. 2430-2441, 2012.
-
(2012)
The Journal of Neuroscience
, vol.32
, Issue.7
, pp. 2430-2441
-
-
Shahpasand, K.1
Uemura, I.2
Saito, T.3
-
87
-
-
62849088641
-
Theamino terminus of tau inhibits kinesin-dependent axonal transport: Implications for filament toxicity
-
N. E. LaPointe, G.Morfini, G. Pigino et al., "Theamino terminus of tau inhibits kinesin-dependent axonal transport: implications for filament toxicity, " Journal of Neuroscience Research, vol. 87, no. 2, pp. 440-451, 2009.
-
(2009)
Journal of Neuroscience Research
, vol.87
, Issue.2
, pp. 440-451
-
-
Lapointe, N.E.1
Morfini, G.2
Pigino, G.3
-
88
-
-
80053289984
-
Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain
-
K. J. Kopeikina, G. A. Carlson, R. Pitstick et al., "Tau accumulation causes mitochondrial distribution deficits in neurons in a mouse model of tauopathy and in human Alzheimer's disease brain, " The American Journal of Pathology, vol. 179, no. 4, pp. 2071-2082, 2011.
-
(2011)
The American Journal of Pathology
, vol.179
, Issue.4
, pp. 2071-2082
-
-
Kopeikina, K.J.1
Carlson, G.A.2
Pitstick, R.3
-
89
-
-
84881611195
-
Motile axonalmitochondria contribute to the variability of presynaptic strength
-
T. Sun, H. Qiao, P.-Y. Pan, Y. Chen, and Z.-H. Sheng, "Motile axonalmitochondria contribute to the variability of presynaptic strength, " Cell Reports, vol. 4, no. 3, pp. 413-419, 2013.
-
(2013)
Cell Reports
, vol.4
, Issue.3
, pp. 413-419
-
-
Sun, T.1
Qiao, H.2
Pan, P.-Y.3
Chen, Y.4
Sheng, Z.-H.5
-
90
-
-
84903957220
-
Mitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons
-
N. Ohnoa, H. Chianga, D. J. Mahada et al., "Mitochondrial immobilization mediated by syntaphilin facilitates survival of demyelinated axons, " Proceedings of the National Academy of Sciences of the United States of America, vol. 111, no. 27, pp. 9953-9958, 2014.
-
(2014)
Proceedings of the National Academy of Sciences of the United States of America
, vol.111
, Issue.27
, pp. 9953-9958
-
-
Ohnoa, N.1
Chianga, H.2
Mahada, D.J.3
-
91
-
-
84923355252
-
Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo
-
P. M. Rappold, M. Cui, J. C. Grima et al., "Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo, " Nature Communications, vol. 5, article 5244, 2014.
-
(2014)
Nature Communications
, vol.5
-
-
Rappold, P.M.1
Cui, M.2
Grima, J.C.3
-
92
-
-
84901948619
-
Inhibitors ofmitochondrial fission as a therapeutic strategy for diseases with oxidative stress and mitochondrial dysfunction
-
P. H. Reddy, "Inhibitors ofmitochondrial fission as a therapeutic strategy for diseases with oxidative stress and mitochondrial dysfunction, " Journal of Alzheimer's Disease, vol. 40, no. 2, pp. 245-256, 2014.
-
(2014)
Journal of Alzheimer's Disease
, vol.40
, Issue.2
, pp. 245-256
-
-
Reddy, P.H.1
-
93
-
-
84884605867
-
Improvement of mitochondrial function and dynamics by the metabolic enhancer piracetam
-
C. Stockburger, C. Kurz, K. A. Koch, S. H. Eckert, K. Leuner, andW. E.Müller, "Improvement of mitochondrial function and dynamics by the metabolic enhancer piracetam, " Biochemical Society Transactions, vol. 41, no. 5, pp. 1331-1334, 2013.
-
(2013)
Biochemical Society Transactions
, vol.41
, Issue.5
, pp. 1331-1334
-
-
Stockburger, C.1
Kurz, C.2
Koch, K.A.3
Eckert, S.H.4
Leuner, K.5
Müller, W.E.6
-
94
-
-
78650895891
-
High-glucose stimulation increases reactive oxygen species production through the calcium and mitogen-activated protein kinase-mediated activation of mitochondrial fission
-
T. Yu, B. S. Jhun, and Y. Yoon, "High-glucose stimulation increases reactive oxygen species production through the calcium and mitogen-activated protein kinase-mediated activation of mitochondrial fission, " Antioxidants & Redox Signaling, vol. 14, no. 3, pp. 425-437, 2011.
-
(2011)
Antioxidants & Redox Signaling
, vol.14
, Issue.3
, pp. 425-437
-
-
Yu, T.1
Jhun, B.S.2
Yoon, Y.3
-
95
-
-
84890247564
-
Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell
-
X. Gan, S. Huang, L. Wu et al., "Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cell, " Biochimica et Biophysica Acta, vol. 1842, no. 2, pp. 220-231, 2014.
-
(2014)
Biochimica et Biophysica Acta
, vol.1842
, Issue.2
, pp. 220-231
-
-
Gan, X.1
Huang, S.2
Wu, L.3
-
96
-
-
84892710629
-
Reduced VDAC1 protects against Alzheimer's disease, mitochondria, and synaptic deficiencies
-
M.Manczak, T.Sheiko, W. J. Craigen, andP.H.Reddy, "Reduced VDAC1 protects against Alzheimer's disease, mitochondria, and synaptic deficiencies, " Journal of Alzheimer's Disease, vol. 37, no. 4, pp. 679-690, 2013.
-
(2013)
Journal of Alzheimer's Disease
, vol.37
, Issue.4
, pp. 679-690
-
-
Manczak, M.1
Sheiko, T.2
Craigen, W.J.3
Reddy, P.H.4
-
97
-
-
77956525855
-
HDAC6 regulates mitochondrial transport in hippocampal neurons
-
S. Chen, G. C. Owens, H. Makarenkova, and D. B. Edelman, "HDAC6 regulates mitochondrial transport in hippocampal neurons, " PLoS ONE, vol. 5, no. 5, Article ID e10848, 2010.
-
(2010)
PLoS ONE
, vol.5
, Issue.5
-
-
Chen, S.1
Owens, G.C.2
Makarenkova, H.3
Edelman, D.B.4
-
98
-
-
84871946821
-
Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease
-
N. Govindarajan, P. Rao, S. Burkhardt et al., "Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease, " EMBO Molecular Medicine, vol. 5, no. 1, pp. 52-63, 2013.
-
(2013)
EMBO Molecular Medicine
, vol.5
, Issue.1
, pp. 52-63
-
-
Govindarajan, N.1
Rao, P.2
Burkhardt, S.3
-
99
-
-
84869231972
-
Mitochondriatargeted antioxidant SS31 prevents Amyloid beta-induced mitochondrial abnormalities and synaptic degeneration in Alzheimer's disease
-
M. J. Calkins, M. Manczak, and P. H. Reddy, "Mitochondriatargeted antioxidant SS31 prevents Amyloid beta-induced mitochondrial abnormalities and synaptic degeneration in Alzheimer's disease, " Pharmaceuticals, vol. 5, no. 10, pp. 1103-1119, 2012.
-
(2012)
Pharmaceuticals
, vol.5
, Issue.10
, pp. 1103-1119
-
-
Calkins, M.J.1
Manczak, M.2
Reddy, P.H.3
-
100
-
-
84862325005
-
Mitochondriatargeted catalase reduces abnormal APP processing, amyloid β production and BACE1 in a mouse model of Alzheimer's disease: Implications for neuroprotection and lifespan extension
-
P. Mao, M. Manczak, M. J. Calkins et al., "Mitochondriatargeted catalase reduces abnormal APP processing, amyloid β production and BACE1 in a mouse model of Alzheimer's disease: implications for neuroprotection and lifespan extension, " HumanMolecular Genetics, vol. 21, no. 13, Article IDdds128, pp. 2973-2990, 2012.
-
(2012)
HumanMolecular Genetics
, vol.21
, Issue.13
, pp. 2973-2990
-
-
Mao, P.1
Manczak, M.2
Calkins, M.J.3
-
101
-
-
84899885579
-
Loss of the m-AAA protease subunit AFG3L2 causesmitochondrial transport defects and tau hyperphosphorylation
-
A. K. Kondadi, S. Wang, S. Montagner et al., "Loss of the m-AAA protease subunit AFG3L2 causesmitochondrial transport defects and tau hyperphosphorylation, " The EMBO Journal, vol. 33, no. 9, pp. 1011-1026, 2014.
-
(2014)
The EMBO Journal
, vol.33
, Issue.9
, pp. 1011-1026
-
-
Kondadi, A.K.1
Wang, S.2
Montagner, S.3
-
102
-
-
84855687153
-
Impairedmitochondrialbiogenesis contributes to mitochondrial dysfunction in Alzheimer's disease
-
B. Sheng, X.Wang, B.Suet al., "Impairedmitochondrialbiogenesis contributes to mitochondrial dysfunction in Alzheimer's disease, " Journal of Neurochemistry, vol. 120, no. 3, pp. 419-429, 2012.
-
(2012)
Journal of Neurochemistry
, vol.120
, Issue.3
, pp. 419-429
-
-
Sheng, B.1
Wang, X.2
Suet Al., B.3
-
103
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
J. St-Pierre, S. Drori, M. Uldry et al., "Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators, " Cell, vol. 127, no. 2, pp. 397-408, 2006.
-
(2006)
Cell
, vol.127
, Issue.2
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
-
104
-
-
84925515308
-
Role of PPARγ in the differentiation and function of neurons
-
R. A. Quintanilla, E. Utreras, and F. A. Cabezas-Opazo, "Role of PPARγ in the differentiation and function of neurons, " PPAR Research, vol. 2014, Article ID 768594, 9 pages, 2014.
-
(2014)
PPAR Research
, vol.2014
-
-
Quintanilla, R.A.1
Utreras, E.2
Cabezas-Opazo, F.A.3
-
105
-
-
84866333520
-
The Nrf2-antioxidant response element pathway: A target for regulating energy metabolism
-
E. E. Vomhof-DeKrey and M. J. Picklo, "The Nrf2-antioxidant response element pathway: a target for regulating energy metabolism, " The Journal of Nutritional Biochemistry, vol. 23, no. 10, pp. 1201-1206, 2012.
-
(2012)
The Journal of Nutritional Biochemistry
, vol.23
, Issue.10
, pp. 1201-1206
-
-
Vomhof-Dekrey, E.E.1
Picklo, M.J.2
-
106
-
-
70349482547
-
Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease
-
K. Kanninen, R. Heikkinen, T. Malm et al., "Intrahippocampal injection of a lentiviral vector expressing Nrf2 improves spatial learning in a mouse model of Alzheimer's disease, " Proceedings of the National Academy of Sciences of the United States of America, vol. 106, no. 38, pp. 16505-16510, 2009.
-
(2009)
Proceedings of the National Academy of Sciences of the United States of America
, vol.106
, Issue.38
, pp. 16505-16510
-
-
Kanninen, K.1
Heikkinen, R.2
Malm, T.3
-
107
-
-
33846073880
-
Expression of Nrf2 in neurodegenerative diseases
-
C. P. Ramsey, C. A. Glass, M. B.Montgomery et al., "Expression of Nrf2 in neurodegenerative diseases, " Journal of Neuropathology and Experimental Neurology, vol. 66, no. 1, pp. 75-85, 2007.
-
(2007)
Journal of Neuropathology and Experimental Neurology
, vol.66
, Issue.1
, pp. 75-85
-
-
Ramsey, C.P.1
Glass, C.A.2
Montgomery, M.B.3
-
108
-
-
53749088028
-
Nuclear factor erythroid 2-related factor 2 protects against beta amyloid
-
K.Kanninen, T.M.Malm, H. K. Jyrkkänen et al., "Nuclear factor erythroid 2-related factor 2 protects against beta amyloid, " Molecular and Cellular Neuroscience, vol. 39, no. 3, pp. 302-313, 2008.
-
(2008)
Molecular and Cellular Neuroscience
, vol.39
, Issue.3
, pp. 302-313
-
-
Kanninen, K.1
Malm, T.M.2
Jyrkkänen, H.K.3
-
109
-
-
44249103744
-
Kavalactones protect neural cells against amyloid β peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related factor 2 activation
-
C. J. Wruck, M. E. Götz, T. Herdegen, D. Varoga, L.-O. Brandenburg, and T. Pufe, "Kavalactones protect neural cells against amyloid β peptide-induced neurotoxicity via extracellular signal-regulated kinase 1/2-dependent nuclear factor erythroid 2-related factor 2 activation, " Molecular Pharmacology, vol. 73, no. 6, pp. 1785-1795, 2008.
-
(2008)
Molecular Pharmacology
, vol.73
, Issue.6
, pp. 1785-1795
-
-
Wruck, C.J.1
Götz, M.E.2
Herdegen, T.3
Varoga, D.4
Brandenburg, L.-O.5
Pufe, T.6
-
110
-
-
84897093101
-
Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52
-
C. Jo, S. Gundemir, S. Pritchard, Y. N. Jin, I. Rahman, and G. V. W. Johnson, "Nrf2 reduces levels of phosphorylated tau protein by inducing autophagy adaptor protein NDP52, " Nature Communications, vol. 5, article 3496, 2014.
-
(2014)
Nature Communications
, vol.5
-
-
Jo, C.1
Gundemir, S.2
Pritchard, S.3
Jin, Y.N.4
Rahman, I.5
Johnson, G.V.W.6
-
111
-
-
84859988979
-
Impaired mitochondrial function in psychiatric disorders
-
H. Manji, T. Kato, N. A. Di Prospero et al., "Impaired mitochondrial function in psychiatric disorders, " Nature Reviews Neuroscience, vol. 13, no. 5, pp. 293-307, 2012.
-
(2012)
Nature Reviews Neuroscience
, vol.13
, Issue.5
, pp. 293-307
-
-
Manji, H.1
Kato, T.2
Di Prospero, N.A.3
|