Mitochondrial oxidative stress causes hyperphosphorylation of tau

PLoS ONE

Volumn 2, Issue 6, 2007, Pages

  Melov, Simon ^a   Adlard, Paul A ^b   Morten, Karl ^a   Johnson, Felicity ^a   Golden, Tamara R ^a   Hinerfeld, Doug ^a   Schilling, Birgit ^a   Mavros, Christine ^b   Masters, Colin L ^b   Volitakis, Irene ^b   Li, Qiao Xin ^b   Laughton, Katrina ^b   Hubbard, Alan ^c   Cherny, Robert A ^b   Gibson, Brad ^a   Bush, Ashley I ^b,d  

^a BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; ANTIOXIDANT; COPPER; EPITOPE; MANGANESE; MANGANESE SUPEROXIDE DISMUTASE; REACTIVE OXYGEN METABOLITE; SERINE; TAU PROTEIN; ZINC; METAL; SUPEROXIDE DISMUTASE;

AGING; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN LEVEL; BRAIN MITOCHONDRION; CATALYSIS; CONTROLLED STUDY; DEGENERATIVE DISEASE; DISEASE EXACERBATION; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FEMALE; HETEROZYGOSITY; KNOCKOUT MOUSE; LIFESPAN; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHENOTYPIC VARIATION; PROTEIN PHOSPHORYLATION; ANIMAL; C57BL MOUSE; CHEMISTRY; DRUG EFFECT; ELECTROSPRAY MASS SPECTROMETRY; ENZYME IMMUNOASSAY; IMMUNOPRECIPITATION; METABOLISM; MITOCHONDRION; MOUSE MUTANT; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; SENILE PLAQUE; WESTERN BLOTTING;

MUS;

ANIMALS; ANTIOXIDANTS; BLOTTING, WESTERN; FEMALE; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; MALE; METALS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; OXIDATIVE STRESS; PHOSPHORYLATION; REACTIVE OXYGEN SPECIES; SENILE PLAQUES; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUPEROXIDE DISMUTASE; TAU PROTEINS;

EID: 38849150935     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0000536     Document Type: Article

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