A mouse model of amyloid β oligomers: Their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo

Journal of Neuroscience

Volumn 30, Issue 14, 2010, Pages 4845-4856

  Tomiyama, Takami ^a,b   Matsuyama, Shogo ^b   Iso, Hiroyuki ^c   Umeda, Tomohiro ^a,b   Takuma, Hiroshi ^a   Ohnishi, Kiyouhisa ^a   Ishibashi, Kenichi ^a   Teraoka, Rie ^a   Sakama, Naomi ^a   Yamashita, Takenari ^a   Nishitsuji, Kazuchika ^a   Ito, Kazuhiro ^a   Shimada, Hiroyuki ^a   Lambert, Mary P ^d   Klein, William L ^d   Mori, Hiroshi ^a,b  

^a OSAKA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b HIMEJI DOKKYO UNIVERSITY   (Japan)

^c HYOGO COLLEGE OF MEDICINE   (Japan)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; OLIGOMER; SYNAPTOPHYSIN; TAU PROTEIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL LOSS; COGNITIVE DEFECT; CONTROLLED STUDY; GENE MUTATION; HIPPOCAMPUS; HISTOPATHOLOGY; IN VIVO STUDY; MEMORY DISORDER; MICROGLIA; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; OLIGOMERIZATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; ANIMALS; CELL DEATH; DISEASE MODELS, ANIMAL; HUMANS; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, TRANSGENIC; NEUROGLIA; NEURONS; PHOSPHORYLATION; SYNAPSES; TAU PROTEINS;

EID: 77950617631     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5825-09.2010     Document Type: Article

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