Key role of mitochondria in Alzheimer's disease synaptic dysfunction

Current Pharmaceutical Design

Volumn 19, Issue 36, 2013, Pages 6440-6450

  Cavallucci, Virve ^a   Ferraina, Caterina ^b   D'Amelio, Marcello ^a,c  

^a IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^b EUROPEAN BRAIN RESEARCH INSTITUTE   (Italy)

^c UNIVERSITY CAMPUS BIO MEDICO   (Italy)

Author keywords

Apoptosis; ATP production; Cell death; Mitochondria dynamics; Neurotransmitter release; Synaptic function

Indexed keywords

AMYLOID PRECURSOR PROTEIN; APOPTOSIS INDUCING FACTOR; APOPTOSOME; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; CASPASE 9; CATALASE; CYCLOPHILIN D; CYTOCHROME C; CYTOCHROME C OXIDASE; GLUTATHIONE PEROXIDASE; MELANOMA ANTIGEN; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; NERVE GROWTH FACTOR; NEUROTROPHIC FACTOR; NEUROTROPHIN 3; NEUROTROPHIN RECEPTOR; NEUROTROPHIN RECEPTOR P75; PEPTIDYLPROLYL ISOMERASE; PRESENILIN; PRESENILIN 1; PRESENILIN 2; REACTIVE OXYGEN METABOLITE; RYANODINE RECEPTOR; SEROTONIN 1A RECEPTOR; SUPEROXIDE DISMUTASE; TAU PROTEIN; VOLTAGE DEPENDENT ANION CHANNEL;

ALZHEIMER DISEASE; AMYLOID PLAQUE; APOPTOSIS; AUTOSOMAL DOMINANT INHERITANCE; AUTOSOMAL DOMINANT OPTIC ATROPHY; BRAIN MITOCHONDRION; BRAIN TISSUE; CELL MEMBRANE; COGNITIVE DEFECT; DENDRITIC SPINE; DEPOLARIZATION; DISEASE ASSOCIATION; DOWN REGULATION; ELECTRON TRANSPORT; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; EXOCYTOSIS; FIBROBLAST; FRONTAL CORTEX; GABAERGIC TRANSMISSION; GENE LINKAGE DISEQUILIBRIUM; GLUCOSE METABOLISM; GLUCOSE UTILIZATION; HIPPOCAMPAL NEURONAL CULTURE; HIPPOCAMPUS; HUMAN; INTRACELLULAR SPACE; LEARNING DISORDER; LIPID PEROXIDATION; LIVER MITOCHONDRION; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MEMORY DISORDER; MILD COGNITIVE IMPAIRMENT; MITOCHONDRIAL DYNAMICS; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; NERVE CELL PLASTICITY; NERVE FIBER TRANSPORT; NEUROBLASTOMA CELL; NEUROTRANSMITTER RELEASE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; OXIDATIVE STRESS; OXYGEN CONSUMPTION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RESPIRATORY CHAIN; REVIEW; SCHWANN CELL; SENILE PLAQUE; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; SPATIAL LEARNING; SYNAPSE VESICLE; SYNAPTIC POTENTIAL; SYNAPTIC TRANSMISSION; TEMPORAL CORTEX; WILD TYPE;

ALZHEIMER DISEASE; ANIMALS; HUMANS; MITOCHONDRIA; SYNAPSES;

EID: 84886783440     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612811319360005     Document Type: Review

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