메뉴 건너뛰기




Volumn 8, Issue 9, 2013, Pages

Modifications of Hippocampal Circuits and Early Disruption of Adult Neurogenesis in the Tg2576 Mouse Model of Alzheimer's Disease

Author keywords

[No Author keywords available]

Indexed keywords

CALBINDIN; NEUROPEPTIDE Y;

EID: 84884676997     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0076497     Document Type: Article
Times cited : (75)

References (74)
  • 1
    • 80053630587 scopus 로고    scopus 로고
    • Abeta oligomers inhibit synapse remodelling necessary for memory consolidation
    • doi: 10.1016/j.neurobiolaging.2010.01.001
    • Freir DB, Fedriani R, Scully D, Smith IM, Selkoe DJ, et al. (2011) Abeta oligomers inhibit synapse remodelling necessary for memory consolidation. Neurobiol Aging 32: 2211-2218. doi:10.1016/j.neurobiolaging.2010.01.001. PubMed: 20097446.
    • (2011) Neurobiol Aging , vol.32 , pp. 2211-2218
    • Freir, D.B.1    Fedriani, R.2    Scully, D.3    Smith, I.M.4    Selkoe, D.J.5
  • 2
    • 33846633336 scopus 로고    scopus 로고
    • Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease
    • doi: 10.1523/JNEUROSCI.3501-06.2007
    • Lacor PN, Buniel MC, Furlow PW, Clemente AS, Velasco PT, et al. (2007) Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. J Neurosci 27: 796-807. doi:10.1523/JNEUROSCI.3501-06.2007. PubMed: 17251419.
    • (2007) J Neurosci , vol.27 , pp. 796-807
    • Lacor, P.N.1    Buniel, M.C.2    Furlow, P.W.3    Clemente, A.S.4    Velasco, P.T.5
  • 3
    • 33645038471 scopus 로고    scopus 로고
    • A specific amyloid-beta protein assembly in the brain impairs memory
    • doi: 10.1038/nature04533
    • Lesné S, Koh MT, Kotilinek L, Kayed R, Glabe CG, et al. (2006) A specific amyloid-beta protein assembly in the brain impairs memory. Nature 440: 352-357. doi:10.1038/nature04533. PubMed: 16541076.
    • (2006) Nature , vol.440 , pp. 352-357
    • Lesné, S.1    Koh, M.T.2    Kotilinek, L.3    Kayed, R.4    Glabe, C.G.5
  • 4
    • 70350266228 scopus 로고    scopus 로고
    • Amyloid imaging in aging and dementia: testing the amyloid hypothesis in vivo
    • PubMed: 19847050
    • Rabinovici GD, Jagust WJ, (2009) Amyloid imaging in aging and dementia: testing the amyloid hypothesis in vivo. Behav Neurol 21: 117-128. PubMed: 19847050.
    • (2009) Behav Neurol , vol.21 , pp. 117-128
    • Rabinovici, G.D.1    Jagust, W.J.2
  • 5
    • 0036489445 scopus 로고    scopus 로고
    • The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease
    • PubMed: 11880515
    • Westerman MA, Cooper-Blacketer D, Mariash A, Kotilinek L, Kawarabayashi T, et al. (2002) The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease. J Neurosci 22: 1858-1867. PubMed: 11880515.
    • (2002) J Neurosci , vol.22 , pp. 1858-1867
    • Westerman, M.A.1    Cooper-Blacketer, D.2    Mariash, A.3    Kotilinek, L.4    Kawarabayashi, T.5
  • 6
    • 0042924399 scopus 로고    scopus 로고
    • Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits
    • doi: 10.1073/pnas.1133381100
    • Palop JJ, Jones B, Kekonius L, Chin J, Yu GQ, et al. (2003) Neuronal depletion of calcium-dependent proteins in the dentate gyrus is tightly linked to Alzheimer's disease-related cognitive deficits. Proc Natl Acad Sci U S A 100: 9572-9577. doi:10.1073/pnas.1133381100. PubMed: 12881482.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 9572-9577
    • Palop, J.J.1    Jones, B.2    Kekonius, L.3    Chin, J.4    Yu, G.Q.5
  • 7
    • 27144530643 scopus 로고    scopus 로고
    • Vulnerability of dentate granule cells to disruption of arc expression in human amyloid precursor protein transgenic mice
    • doi: 10.1523/JNEUROSCI.2829-05.2005
    • Palop JJ, Chin J, Bien-Ly N, Massaro C, Yeung BZ, et al. (2005) Vulnerability of dentate granule cells to disruption of arc expression in human amyloid precursor protein transgenic mice. J Neurosci 25: 9686-9693. doi:10.1523/JNEUROSCI.2829-05.2005. PubMed: 16237173.
    • (2005) J Neurosci , vol.25 , pp. 9686-9693
    • Palop, J.J.1    Chin, J.2    Bien-Ly, N.3    Massaro, C.4    Yeung, B.Z.5
  • 8
    • 34548264782 scopus 로고    scopus 로고
    • Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease
    • doi: 10.1016/j.neuron.2007.07.025
    • Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, et al. (2007) Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron 55: 697-711. doi:10.1016/j.neuron.2007.07.025. PubMed: 17785178.
    • (2007) Neuron , vol.55 , pp. 697-711
    • Palop, J.J.1    Chin, J.2    Roberson, E.D.3    Wang, J.4    Thwin, M.T.5
  • 9
    • 84860334015 scopus 로고    scopus 로고
    • Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model
    • doi: 10.1016/j.cell.2012.02.046
    • Verret L, Mann EO, Hang GB, Barth AM, Cobos I, et al. (2012) Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model. Cell 149: 708-721. doi:10.1016/j.cell.2012.02.046. PubMed: 22541439.
    • (2012) Cell , vol.149 , pp. 708-721
    • Verret, L.1    Mann, E.O.2    Hang, G.B.3    Barth, A.M.4    Cobos, I.5
  • 10
    • 27144489060 scopus 로고    scopus 로고
    • Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease
    • doi: 10.1523/JNEUROSCI.2980-05.2005
    • Chin J, Palop JJ, Puoliväli J, Massaro C, Bien-Ly N, et al. (2005) Fyn kinase induces synaptic and cognitive impairments in a transgenic mouse model of Alzheimer's disease. J Neurosci 25: 9694-9703. doi:10.1523/JNEUROSCI.2980-05.2005. PubMed: 16237174.
    • (2005) J Neurosci , vol.25 , pp. 9694-9703
    • Chin, J.1    Palop, J.J.2    Puoliväli, J.3    Massaro, C.4    Bien-Ly, N.5
  • 11
    • 63849180498 scopus 로고    scopus 로고
    • Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy
    • doi: 10.1523/JNEUROSCI.5215-08.2009
    • Minkeviciene R, Rheims S, Dobszay MB, Zilberter M, Hartikainen J, et al. (2009) Amyloid beta-induced neuronal hyperexcitability triggers progressive epilepsy. J Neurosci 29: 3453-3462. doi:10.1523/JNEUROSCI.5215-08.2009. PubMed: 19295151.
    • (2009) J Neurosci , vol.29 , pp. 3453-3462
    • Minkeviciene, R.1    Rheims, S.2    Dobszay, M.B.3    Zilberter, M.4    Hartikainen, J.5
  • 12
    • 77952484484 scopus 로고    scopus 로고
    • Synaptic depression and aberrant excitatory network activity in Alzheimer's disease: two faces of the same coin?
    • doi: 10.1007/s12017-009-8097-7
    • Palop JJ, Mucke L, (2010) Synaptic depression and aberrant excitatory network activity in Alzheimer's disease: two faces of the same coin? Neuromol Med 12: 48-55. doi:10.1007/s12017-009-8097-7. PubMed: 19838821.
    • (2010) Neuromol Med , vol.12 , pp. 48-55
    • Palop, J.J.1    Mucke, L.2
  • 13
    • 77952543738 scopus 로고    scopus 로고
    • Neurogenesis and Alzheimer's disease: at the crossroads
    • doi: 10.1016/j.expneurol.2009.08.009
    • Lazarov O, Marr RA, (2010) Neurogenesis and Alzheimer's disease: at the crossroads. Exp Neurol 223: 267-281. doi:10.1016/j.expneurol.2009.08.009. PubMed: 19699201.
    • (2010) Exp Neurol , vol.223 , pp. 267-281
    • Lazarov, O.1    Marr, R.A.2
  • 14
    • 34547684593 scopus 로고    scopus 로고
    • Hippocampal neurogenesis during normal and pathological aging
    • doi: 10.1016/j.psyneuen.2007.04.014
    • Verret L, Trouche S, Zerwas M, Rampon C, (2007) Hippocampal neurogenesis during normal and pathological aging. Psychoneuroendocrinology 32 (Suppl 1):: S26-S30. doi:10.1016/j.psyneuen.2007.04.014. PubMed: 17629417.
    • (2007) Psychoneuroendocrinology , vol.32 , Issue.SUPPL. 1
    • Verret, L.1    Trouche, S.2    Zerwas, M.3    Rampon, C.4
  • 15
    • 65249124662 scopus 로고    scopus 로고
    • Recruitment of adult-generated neurons into functional hippocampal networks contributes to updating and strengthening of spatial memory
    • doi: 10.1073/pnas.0811054106
    • Trouche S, Bontempi B, Roullet P, Rampon C, (2009) Recruitment of adult-generated neurons into functional hippocampal networks contributes to updating and strengthening of spatial memory. Proc Natl Acad Sci U S A 106: 5919-5924. doi:10.1073/pnas.0811054106. PubMed: 19321751.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 5919-5924
    • Trouche, S.1    Bontempi, B.2    Roullet, P.3    Rampon, C.4
  • 16
    • 39149107803 scopus 로고    scopus 로고
    • Mechanisms and functional implications of adult neurogenesis
    • doi: 10.1016/j.cell.2008.01.033
    • Zhao C, Deng W, Gage FH, (2008) Mechanisms and functional implications of adult neurogenesis. Cell 132: 645-660. doi:10.1016/j.cell.2008.01.033. PubMed: 18295581.
    • (2008) Cell , vol.132 , pp. 645-660
    • Zhao, C.1    Deng, W.2    Gage, F.H.3
  • 17
    • 84863601480 scopus 로고    scopus 로고
    • All in the Family: How the APPs Regulate Neurogenesis
    • PubMed: 22675290
    • Lazarov O, Demars MP, (2012) All in the Family: How the APPs Regulate Neurogenesis. Front Neurosci 6: 81. PubMed: 22675290.
    • (2012) Front Neurosci , vol.6 , pp. 81
    • Lazarov, O.1    Demars, M.P.2
  • 18
    • 47249089923 scopus 로고    scopus 로고
    • Subfield and layer-specific depletion in calbindin-D28K, calretinin and parvalbumin immunoreactivity in the dentate gyrus of amyloid precursor protein/presenilin 1 transgenic mice
    • doi: 10.1016/j.neuroscience.2008.05.023
    • Popović M, Caballero-Bleda M, Kadish I, Van Groen T, (2008) Subfield and layer-specific depletion in calbindin-D28K, calretinin and parvalbumin immunoreactivity in the dentate gyrus of amyloid precursor protein/presenilin 1 transgenic mice. Neuroscience 155: 182-191. doi:10.1016/j.neuroscience.2008.05.023. PubMed: 18583063.
    • (2008) Neuroscience , vol.155 , pp. 182-191
    • Popović, M.1    Caballero-Bleda, M.2    Kadish, I.3    Van Groen, T.4
  • 19
    • 34250815052 scopus 로고    scopus 로고
    • Alzheimer's-type amyloidosis in transgenic mice impairs survival of newborn neurons derived from adult hippocampal neurogenesis
    • doi: 10.1523/JNEUROSCI.5564-06.2007
    • Verret L, Jankowsky JL, Xu GM, Borchelt DR, Rampon C, (2007) Alzheimer's-type amyloidosis in transgenic mice impairs survival of newborn neurons derived from adult hippocampal neurogenesis. J Neurosci 27: 6771-6780. doi:10.1523/JNEUROSCI.5564-06.2007. PubMed: 17581964.
    • (2007) J Neurosci , vol.27 , pp. 6771-6780
    • Verret, L.1    Jankowsky, J.L.2    Xu, G.M.3    Borchelt, D.R.4    Rampon, C.5
  • 20
    • 70450250252 scopus 로고    scopus 로고
    • Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease
    • doi: 10.1016/j.stem.2009.10.003
    • Sun B, Halabisky B, Zhou Y, Palop JJ, Yu G, et al. (2009) Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease. Cell Stem Cell 5: 624-633. doi:10.1016/j.stem.2009.10.003. PubMed: 19951690.
    • (2009) Cell Stem Cell , vol.5 , pp. 624-633
    • Sun, B.1    Halabisky, B.2    Zhou, Y.3    Palop, J.J.4    Yu, G.5
  • 21
    • 46749144083 scopus 로고    scopus 로고
    • Age-dependent loss of dentate gyrus granule cells in APP/PS1KI mice
    • doi: 10.1016/j.brainres.2008.05.052
    • Cotel MC, Bayer TA, Wirths O, (2008) Age-dependent loss of dentate gyrus granule cells in APP/PS1KI mice. Brain Res 1222: 207-213. doi:10.1016/j.brainres.2008.05.052. PubMed: 18585693.
    • (2008) Brain Res , vol.1222 , pp. 207-213
    • Cotel, M.C.1    Bayer, T.A.2    Wirths, O.3
  • 22
    • 79952899908 scopus 로고    scopus 로고
    • Impaired neurogenesis, neuronal loss, and brain functional deficits in the APPxPS1-Ki mouse model of Alzheimer's disease
    • doi: 10.1016/j.neurobiolaging.2009.03.009
    • Faure A, Verret L, Bozon B, El Tannir El Tayara N, Ly M, et al. (2011) Impaired neurogenesis, neuronal loss, and brain functional deficits in the APPxPS1-Ki mouse model of Alzheimer's disease. Neurobiol Aging 32: 407-418. doi:10.1016/j.neurobiolaging.2009.03.009. PubMed: 19398247.
    • (2011) Neurobiol Aging , vol.32 , pp. 407-418
    • Faure, A.1    Verret, L.2    Bozon, B.3    El Tannir El Tayara, N.4    Ly, M.5
  • 23
    • 0029742199 scopus 로고    scopus 로고
    • Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
    • doi: 10.1126/science.274.5284.99
    • Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, et al. (1996) Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274: 99-102. doi:10.1126/science.274.5284.99. PubMed: 8810256.
    • (1996) Science , vol.274 , pp. 99-102
    • Hsiao, K.1    Chapman, P.2    Nilsen, S.3    Eckman, C.4    Harigaya, Y.5
  • 24
    • 0242383891 scopus 로고    scopus 로고
    • Alterations in cholinergic and non-cholinergic neurotransmitter receptor densities in transgenic Tg2576 mouse brain with beta-amyloid plaque pathology
    • doi: 10.1016/j.ijdevneu.2003.08.001
    • Klingner M, Apelt J, Kumar A, Sorger D, Sabri O, et al. (2003) Alterations in cholinergic and non-cholinergic neurotransmitter receptor densities in transgenic Tg2576 mouse brain with beta-amyloid plaque pathology. Int J Dev Neurosci 21: 357-369. doi:10.1016/j.ijdevneu.2003.08.001. PubMed: 14599482.
    • (2003) Int J Dev Neurosci , vol.21 , pp. 357-369
    • Klingner, M.1    Apelt, J.2    Kumar, A.3    Sorger, D.4    Sabri, O.5
  • 25
    • 24944458139 scopus 로고    scopus 로고
    • Early changes in Abeta levels in the brain of APPswe transgenic mice--implication on synaptic density, alpha7 neuronal nicotinic acetylcholine- and N-methyl-D-aspartate receptor levels
    • doi: 10.1016/j.mcn.2005.07.012
    • Unger C, Hedberg MM, Mustafiz T, Svedberg MM, Nordberg A, (2005) Early changes in Abeta levels in the brain of APPswe transgenic mice--implication on synaptic density, alpha7 neuronal nicotinic acetylcholine- and N-methyl-D-aspartate receptor levels. Mol Cell Neurosci 30: 218-227. doi:10.1016/j.mcn.2005.07.012. PubMed: 16107318.
    • (2005) Mol Cell Neurosci , vol.30 , pp. 218-227
    • Unger, C.1    Hedberg, M.M.2    Mustafiz, T.3    Svedberg, M.M.4    Nordberg, A.5
  • 26
    • 0035863055 scopus 로고    scopus 로고
    • Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease
    • PubMed: 11160418
    • Kawarabayashi T, Younkin LH, Saido TC, Shoji M, Ashe KH, et al. (2001) Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. J Neurosci 21: 372-381. PubMed: 11160418.
    • (2001) J Neurosci , vol.21 , pp. 372-381
    • Kawarabayashi, T.1    Younkin, L.H.2    Saido, T.C.3    Shoji, M.4    Ashe, K.H.5
  • 27
    • 0037088959 scopus 로고    scopus 로고
    • Intra- and intertask relationships in a behavioral test battery given to Tg2576 transgenic mice and controls
    • doi: 10.1016/S0031-9384(02)00640-6
    • Arendash GW, King DL, (2002) Intra- and intertask relationships in a behavioral test battery given to Tg2576 transgenic mice and controls. Physiol Behav 75: 643-652. doi:10.1016/S0031-9384(02)00640-6. PubMed: 12020729.
    • (2002) Physiol Behav , vol.75 , pp. 643-652
    • Arendash, G.W.1    King, D.L.2
  • 28
    • 43249100232 scopus 로고    scopus 로고
    • Effects of the genetic background on cognitive performances of TG2576 mice
    • doi: 10.1016/j.bbr.2008.03.017
    • Lassalle JM, Halley H, Daumas S, Verret L, Francés B, (2008) Effects of the genetic background on cognitive performances of TG2576 mice. Behav Brain Res 191: 104-110. doi:10.1016/j.bbr.2008.03.017. PubMed: 18433892.
    • (2008) Behav Brain Res , vol.191 , pp. 104-110
    • Lassalle, J.M.1    Halley, H.2    Daumas, S.3    Verret, L.4    Francés, B.5
  • 29
    • 70449368211 scopus 로고    scopus 로고
    • X11beta rescues memory and long-term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice
    • doi: 10.1093/hmg/ddp408
    • Mitchell JC, Ariff BB, Yates DM, Lau KF, Perkinton MS, et al. (2009) X11beta rescues memory and long-term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice. Hum Mol Genet 18: 4492-4500. doi:10.1093/hmg/ddp408. PubMed: 19744962.
    • (2009) Hum Mol Genet , vol.18 , pp. 4492-4500
    • Mitchell, J.C.1    Ariff, B.B.2    Yates, D.M.3    Lau, K.F.4    Perkinton, M.S.5
  • 30
    • 80052335857 scopus 로고    scopus 로고
    • Which memory task for my mouse? A systematic review of spatial memory performance in the Tg2576 Alzheimer's mouse model
    • Stewart S, Cacucci F, Lever C, (2011) Which memory task for my mouse? A systematic review of spatial memory performance in the Tg2576 Alzheimer's mouse model. J Alzheimers Dis 26: 105-126.
    • (2011) J Alzheimers Dis , vol.26 , pp. 105-126
    • Stewart, S.1    Cacucci, F.2    Lever, C.3
  • 31
    • 84868099665 scopus 로고    scopus 로고
    • Transient enriched housing before amyloidosis onset sustains cognitive improvement in Tg2576 mice
    • PubMed: 22727275
    • Verret L, Krezymon A, Halley H, Trouche S, Zerwas M, et al. (2013) Transient enriched housing before amyloidosis onset sustains cognitive improvement in Tg2576 mice. Neurobiol Aging, 34: 211-25. PubMed: 22727275.
    • (2013) Neurobiol Aging , vol.34 , pp. 211-225
    • Verret, L.1    Krezymon, A.2    Halley, H.3    Trouche, S.4    Zerwas, M.5
  • 32
    • 0028810244 scopus 로고
    • Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins
    • doi: 10.1016/0896-6273(95)90107-8
    • Hsiao KK, Borchelt DR, Olson K, Johannsdottir R, Kitt C, et al. (1995) Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins. Neuron 15: 1203-1218. doi:10.1016/0896-6273(95)90107-8. PubMed: 7576662.
    • (1995) Neuron , vol.15 , pp. 1203-1218
    • Hsiao, K.K.1    Borchelt, D.R.2    Olson, K.3    Johannsdottir, R.4    Kitt, C.5
  • 33
    • 62849111110 scopus 로고    scopus 로고
    • Neurogenin2 directs granule neuroblast production and amplification while NeuroD1 specifies neuronal fate during hippocampal neurogenesis
    • doi: 10.1371/journal.pone.0004779
    • Roybon L, Hjalt T, Stott S, Guillemot F, Li JY, et al. (2009) Neurogenin2 directs granule neuroblast production and amplification while NeuroD1 specifies neuronal fate during hippocampal neurogenesis. PLOS ONE 4: e4779. doi:10.1371/journal.pone.0004779. PubMed: 19274100.
    • (2009) PLOS ONE , vol.4
    • Roybon, L.1    Hjalt, T.2    Stott, S.3    Guillemot, F.4    Li, J.Y.5
  • 34
    • 27744484327 scopus 로고    scopus 로고
    • Neuronal differentiation in the adult hippocampus recapitulates embryonic development
    • doi: 10.1523/JNEUROSCI.3114-05.2005
    • Espósito MS, Piatti VC, Laplagne DA, Morgenstern NA, Ferrari CC, et al. (2005) Neuronal differentiation in the adult hippocampus recapitulates embryonic development. J Neurosci 25: 10074-10086. doi:10.1523/JNEUROSCI.3114-05.2005. PubMed: 16267214.
    • (2005) J Neurosci , vol.25 , pp. 10074-10086
    • Espósito, M.S.1    Piatti, V.C.2    Laplagne, D.A.3    Morgenstern, N.A.4    Ferrari, C.C.5
  • 35
    • 30644474606 scopus 로고    scopus 로고
    • Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus
    • doi: 10.1523/JNEUROSCI.3648-05.2006
    • Zhao C, Teng EM, Summers RG Jr., Ming GL, Gage FH, (2006) Distinct morphological stages of dentate granule neuron maturation in the adult mouse hippocampus. J Neurosci 26: 3-11. doi:10.1523/JNEUROSCI.3648-05.2006. PubMed: 16399667.
    • (2006) J Neurosci , vol.26 , pp. 3-11
    • Zhao, C.1    Teng, E.M.2    Summers Jr., R.G.3    Ming, G.L.4    Gage, F.H.5
  • 36
    • 0026734317 scopus 로고
    • Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation
    • PubMed: 1613552
    • Harris KM, Jensen FE, Tsao B, (1992) Three-dimensional structure of dendritic spines and synapses in rat hippocampus (CA1) at postnatal day 15 and adult ages: implications for the maturation of synaptic physiology and long-term potentiation. J Neurosci 12: 2685-2705. PubMed: 1613552.
    • (1992) J Neurosci , vol.12 , pp. 2685-2705
    • Harris, K.M.1    Jensen, F.E.2    Tsao, B.3
  • 37
    • 65249091454 scopus 로고    scopus 로고
    • Epilepsy and cognitive impairments in Alzheimer disease
    • doi: 10.1001/archneurol.2009.15
    • Palop JJ, Mucke L, (2009) Epilepsy and cognitive impairments in Alzheimer disease. Arch Neurol 66: 435-440. doi:10.1001/archneurol.2009.15. PubMed: 19204149.
    • (2009) Arch Neurol , vol.66 , pp. 435-440
    • Palop, J.J.1    Mucke, L.2
  • 38
    • 78049283756 scopus 로고    scopus 로고
    • Transsynaptic progression of amyloid-beta-induced neuronal dysfunction within the entorhinal-hippocampal network
    • doi: 10.1016/j.neuron.2010.10.020
    • Harris JA, Devidze N, Verret L, Ho K, Halabisky B, et al. (2010) Transsynaptic progression of amyloid-beta-induced neuronal dysfunction within the entorhinal-hippocampal network. Neuron 68: 428-441. doi:10.1016/j.neuron.2010.10.020. PubMed: 21040845.
    • (2010) Neuron , vol.68 , pp. 428-441
    • Harris, J.A.1    Devidze, N.2    Verret, L.3    Ho, K.4    Halabisky, B.5
  • 39
    • 0026786520 scopus 로고
    • Functional changes in neuropeptide Y- and somatostatin-containing neurons induced by limbic seizures in the rat
    • doi: 10.1016/0306-4522(92)90207-I
    • Sperk G, Marksteiner J, Gruber B, Bellmann R, Mahata M, et al. (1992) Functional changes in neuropeptide Y- and somatostatin-containing neurons induced by limbic seizures in the rat. Neuroscience 50: 831-846. doi:10.1016/0306-4522(92)90207-I. PubMed: 1360155.
    • (1992) Neuroscience , vol.50 , pp. 831-846
    • Sperk, G.1    Marksteiner, J.2    Gruber, B.3    Bellmann, R.4    Mahata, M.5
  • 40
    • 34548258322 scopus 로고    scopus 로고
    • Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models
    • doi: 10.1074/jbc.M701078200
    • Cheng IH, Scearce-Levie K, Legleiter J, Palop JJ, Gerstein H, et al. (2007) Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models. J Biol Chem 282: 23818-23828. doi:10.1074/jbc.M701078200. PubMed: 17548355.
    • (2007) J Biol Chem , vol.282 , pp. 23818-23828
    • Cheng, I.H.1    Scearce-Levie, K.2    Legleiter, J.3    Palop, J.J.4    Gerstein, H.5
  • 41
    • 0037775776 scopus 로고    scopus 로고
    • Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice
    • PubMed: 12832546
    • Dickey CA, Loring JF, Montgomery J, Gordon MN, Eastman PS, et al. (2003) Selectively reduced expression of synaptic plasticity-related genes in amyloid precursor protein + presenilin-1 transgenic mice. J Neurosci 23: 5219-5226. PubMed: 12832546.
    • (2003) J Neurosci , vol.23 , pp. 5219-5226
    • Dickey, C.A.1    Loring, J.F.2    Montgomery, J.3    Gordon, M.N.4    Eastman, P.S.5
  • 42
    • 84855921307 scopus 로고    scopus 로고
    • Requirement of adult-born neurons for hippocampus-dependent learning
    • doi: 10.1016/j.bbr.2011.07.001
    • Marín-Burgin A, Schinder AF, (2012) Requirement of adult-born neurons for hippocampus-dependent learning. Behav Brain Res 227: 391-399. doi:10.1016/j.bbr.2011.07.001. PubMed: 21763727.
    • (2012) Behav Brain Res , vol.227 , pp. 391-399
    • Marín-Burgin, A.1    Schinder, A.F.2
  • 43
    • 84862140584 scopus 로고    scopus 로고
    • Modification of hippocampal circuitry by adult neurogenesis
    • doi: 10.1002/dneu.22014
    • Song J, Christian KM, Ming GL, Song H, (2012) Modification of hippocampal circuitry by adult neurogenesis. Dev Neurobiol 72: 1032-1043. doi:10.1002/dneu.22014. PubMed: 22354697.
    • (2012) Dev Neurobiol , vol.72 , pp. 1032-1043
    • Song, J.1    Christian, K.M.2    Ming, G.L.3    Song, H.4
  • 44
    • 0037262305 scopus 로고    scopus 로고
    • Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice
    • doi: 10.1242/dev.00203
    • Kempermann G, Gast D, Kronenberg G, Yamaguchi M, Gage FH, (2003) Early determination and long-term persistence of adult-generated new neurons in the hippocampus of mice. Development 130: 391-399. doi:10.1242/dev.00203. PubMed: 12466205.
    • (2003) Development , vol.130 , pp. 391-399
    • Kempermann, G.1    Gast, D.2    Kronenberg, G.3    Yamaguchi, M.4    Gage, F.H.5
  • 45
    • 19944430637 scopus 로고    scopus 로고
    • Doublecortin expression levels in adult brain reflect neurogenesis
    • doi: 10.1111/j.1460-9568.2004.03813.x
    • Couillard-Despres S, Winner B, Schaubeck S, Aigner R, Vroemen M, et al. (2005) Doublecortin expression levels in adult brain reflect neurogenesis. Eur J Neurosci 21: 1-14. doi:10.1111/j.1460-9568.2004.03813.x. PubMed: 15654838.
    • (2005) Eur J Neurosci , vol.21 , pp. 1-14
    • Couillard-Despres, S.1    Winner, B.2    Schaubeck, S.3    Aigner, R.4    Vroemen, M.5
  • 46
    • 77649339173 scopus 로고    scopus 로고
    • A symphony of signals conducts early and late stages of adult neurogenesis
    • doi: 10.1016/j.neuropharm.2010.01.010
    • Pathania M, Yan LD, Bordey A, (2010) A symphony of signals conducts early and late stages of adult neurogenesis. Neuropharmacology 58: 865-876. doi:10.1016/j.neuropharm.2010.01.010. PubMed: 20097213.
    • (2010) Neuropharmacology , vol.58 , pp. 865-876
    • Pathania, M.1    Yan, L.D.2    Bordey, A.3
  • 47
    • 77951498581 scopus 로고    scopus 로고
    • New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory?
    • doi: 10.1038/nrn2822
    • Deng W, Aimone JB, Gage FH, (2010) New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nat Rev Neurosci 11: 339-350. doi:10.1038/nrn2822. PubMed: 20354534.
    • (2010) Nat Rev Neurosci , vol.11 , pp. 339-350
    • Deng, W.1    Aimone, J.B.2    Gage, F.H.3
  • 48
    • 0036194016 scopus 로고    scopus 로고
    • Structure and function of dendritic spines
    • doi: 10.1146/annurev.physiol.64.081501.160008
    • Nimchinsky EA, Sabatini BL, Svoboda K, (2002) Structure and function of dendritic spines. Annu Rev Physiol 64: 313-353. doi:10.1146/annurev.physiol.64.081501.160008. PubMed: 11826272.
    • (2002) Annu Rev Physiol , vol.64 , pp. 313-353
    • Nimchinsky, E.A.1    Sabatini, B.L.2    Svoboda, K.3
  • 49
    • 0036632229 scopus 로고    scopus 로고
    • Molecular regulation of dendritic spine shape and function
    • doi: 10.1159/000065433
    • Sala C, (2002) Molecular regulation of dendritic spine shape and function. Neurosignals 11: 213-223. doi:10.1159/000065433. PubMed: 12393947.
    • (2002) Neurosignals , vol.11 , pp. 213-223
    • Sala, C.1
  • 50
    • 78651506630 scopus 로고    scopus 로고
    • Amyloid-beta/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease
    • doi: 10.1523/JNEUROSCI.4152-10.2011
    • Roberson ED, Halabisky B, Yoo JW, Yao J, Chin J, et al. (2011) Amyloid-beta/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease. J Neurosci 31: 700-711. doi:10.1523/JNEUROSCI.4152-10.2011. PubMed: 21228179.
    • (2011) J Neurosci , vol.31 , pp. 700-711
    • Roberson, E.D.1    Halabisky, B.2    Yoo, J.W.3    Yao, J.4    Chin, J.5
  • 51
    • 34548277538 scopus 로고    scopus 로고
    • Neuropeptide Y in the dentate gyrus
    • doi: 10.1016/S0079-6123(07)63017-9
    • Sperk G, Hamilton T, Colmers WF, (2007) Neuropeptide Y in the dentate gyrus. Prog Brain Res 163: 285-297. doi:10.1016/S0079-6123(07)63017-9. PubMed: 17765725.
    • (2007) Prog Brain Res , vol.163 , pp. 285-297
    • Sperk, G.1    Hamilton, T.2    Colmers, W.F.3
  • 52
    • 0033057715 scopus 로고    scopus 로고
    • Neuropeptide Y: emerging evidence for a functional role in seizure modulation
    • doi: 10.1016/S0166-2236(98)01284-3
    • Vezzani A, Sperk G, Colmers WF, (1999) Neuropeptide Y: emerging evidence for a functional role in seizure modulation. Trends Neurosci 22: 25-30. doi:10.1016/S0166-2236(98)01284-3. PubMed: 10088996.
    • (1999) Trends Neurosci , vol.22 , pp. 25-30
    • Vezzani, A.1    Sperk, G.2    Colmers, W.F.3
  • 53
    • 0030337503 scopus 로고    scopus 로고
    • Interneurons of the hippocampus
    • PubMed: 8915675
    • Freund TF, Buzsáki G, (1996) Interneurons of the hippocampus. Hippocampus 6: 347-470. PubMed: 8915675.
    • (1996) Hippocampus , vol.6 , pp. 347-470
    • Freund, T.F.1    Buzsáki, G.2
  • 54
    • 33644836941 scopus 로고    scopus 로고
    • Plasticity of neuropeptide Y in the dentate gyrus after seizures, and its relevance to seizure-induced neurogenesis
    • PubMed: 16383008
    • Scharfman HE, Gray WP, (2006) Plasticity of neuropeptide Y in the dentate gyrus after seizures, and its relevance to seizure-induced neurogenesis. EXS: pp. 193-211. PubMed: 16383008.
    • (2006) EXS , pp. 193-211
    • Scharfman, H.E.1    Gray, W.P.2
  • 55
    • 0035102386 scopus 로고    scopus 로고
    • Augmented senile plaque load in aged female beta-amyloid precursor protein-transgenic mice
    • doi: 10.1016/S0002-9440(10)64064-3
    • Callahan MJ, Lipinski WJ, Bian F, Durham RA, Pack A, et al. (2001) Augmented senile plaque load in aged female beta-amyloid precursor protein-transgenic mice. Am J Pathol 158: 1173-1177. doi:10.1016/S0002-9440(10)64064-3. PubMed: 11238065.
    • (2001) Am J Pathol , vol.158 , pp. 1173-1177
    • Callahan, M.J.1    Lipinski, W.J.2    Bian, F.3    Durham, R.A.4    Pack, A.5
  • 56
    • 84861844315 scopus 로고    scopus 로고
    • Critical role of soluble amyloid-beta for early hippocampal hyperactivity in a mouse model of Alzheimer's disease
    • doi: 10.1073/pnas.1206171109
    • Busche MA, Chen X, Henning HA, Reichwald J, Staufenbiel M, et al. (2012) Critical role of soluble amyloid-beta for early hippocampal hyperactivity in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 109: 8740-8745. doi:10.1073/pnas.1206171109. PubMed: 22592800.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 8740-8745
    • Busche, M.A.1    Chen, X.2    Henning, H.A.3    Reichwald, J.4    Staufenbiel, M.5
  • 57
    • 52249115856 scopus 로고    scopus 로고
    • Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease
    • doi: 10.1126/science.1162844
    • Busche MA, Eichhoff G, Adelsberger H, Abramowski D, Wiederhold KH, et al. (2008) Clusters of hyperactive neurons near amyloid plaques in a mouse model of Alzheimer's disease. Science 321: 1686-1689. doi:10.1126/science.1162844. PubMed: 18802001.
    • (2008) Science , vol.321 , pp. 1686-1689
    • Busche, M.A.1    Eichhoff, G.2    Adelsberger, H.3    Abramowski, D.4    Wiederhold, K.H.5
  • 58
    • 77954132249 scopus 로고    scopus 로고
    • Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks
    • doi: 10.1038/nn.2583
    • Palop JJ, Mucke L, (2010) Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks. Nat Neurosci 13: 812-818. doi:10.1038/nn.2583. PubMed: 20581818.
    • (2010) Nat Neurosci , vol.13 , pp. 812-818
    • Palop, J.J.1    Mucke, L.2
  • 59
    • 3343015515 scopus 로고    scopus 로고
    • Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress
    • doi: 10.1016/j.neuroscience.2004.05.040
    • Dong H, Goico B, Martin M, Csernansky CA, Bertchume A, et al. (2004) Modulation of hippocampal cell proliferation, memory, and amyloid plaque deposition in APPsw (Tg2576) mutant mice by isolation stress. Neuroscience 127: 601-609. doi:10.1016/j.neuroscience.2004.05.040. PubMed: 15283960.
    • (2004) Neuroscience , vol.127 , pp. 601-609
    • Dong, H.1    Goico, B.2    Martin, M.3    Csernansky, C.A.4    Bertchume, A.5
  • 60
    • 78951489047 scopus 로고    scopus 로고
    • Cell proliferation and total granule cell number in dentate gyrus of transgenic Tg2576 mouse
    • PubMed: 21196944
    • Ihunwo AO, Schliebs R, (2010) Cell proliferation and total granule cell number in dentate gyrus of transgenic Tg2576 mouse. Acta Neurobiol Exp Wars 70: 362-369. PubMed: 21196944.
    • (2010) Acta Neurobiol Exp Wars , vol.70 , pp. 362-369
    • Ihunwo, A.O.1    Schliebs, R.2
  • 61
    • 0042362874 scopus 로고    scopus 로고
    • Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease
    • doi: 10.1046/j.1471-4159.2002.01267.x
    • Haughey NJ, Nath A, Chan SL, Borchard AC, Rao MS, et al. (2002) Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease. J Neurochem 83: 1509-1524. doi:10.1046/j.1471-4159.2002.01267.x. PubMed: 12472904.
    • (2002) J Neurochem , vol.83 , pp. 1509-1524
    • Haughey, N.J.1    Nath, A.2    Chan, S.L.3    Borchard, A.C.4    Rao, M.S.5
  • 62
    • 66249086574 scopus 로고    scopus 로고
    • Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease
    • doi: 10.1523/JNEUROSCI.0421-09.2009
    • He P, Shen Y, (2009) Interruption of beta-catenin signaling reduces neurogenesis in Alzheimer's disease. J Neurosci 29: 6545-6557. doi:10.1523/JNEUROSCI.0421-09.2009. PubMed: 19458225.
    • (2009) J Neurosci , vol.29 , pp. 6545-6557
    • He, P.1    Shen, Y.2
  • 63
    • 2942530513 scopus 로고    scopus 로고
    • Neurogenic effect of beta-amyloid peptide in the development of neural stem cells
    • doi: 10.1523/JNEUROSCI.0974-04.2004
    • López-Toledano MA, Shelanski ML, (2004) Neurogenic effect of beta-amyloid peptide in the development of neural stem cells. J Neurosci 24: 5439-5444. doi:10.1523/JNEUROSCI.0974-04.2004. PubMed: 15190117.
    • (2004) J Neurosci , vol.24 , pp. 5439-5444
    • López-Toledano, M.A.1    Shelanski, M.L.2
  • 64
    • 78650659370 scopus 로고    scopus 로고
    • Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease
    • doi: 10.1038/nn.2709
    • D'Amelio M, Cavallucci V, Middei S, Marchetti C, Pacioni S, et al. (2011) Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease. Nat Neurosci 14: 69-76. doi:10.1038/nn.2709. PubMed: 21151119.
    • (2011) Nat Neurosci , vol.14 , pp. 69-76
    • D'Amelio, M.1    Cavallucci, V.2    Middei, S.3    Marchetti, C.4    Pacioni, S.5
  • 65
    • 70450250252 scopus 로고    scopus 로고
    • Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease
    • 1016/j.stem.2009.10.003
    • Sun B, Halabisky B, Zhou Y, Palop JJ, Yu G, et al. (2009) Imbalance between GABAergic and Glutamatergic Transmission Impairs Adult Neurogenesis in an Animal Model of Alzheimer's Disease. Cell Stem Cell Volumes 6: 10-633 1016/j.stem.2009.10.003.
    • (2009) Cell Stem Cell , vol.6 , pp. 10-633
    • Sun, B.1    Halabisky, B.2    Zhou, Y.3    Palop, J.J.4    Yu, G.5
  • 66
    • 79952610782 scopus 로고    scopus 로고
    • Metal ionophore treatment restores dendritic spine density and synaptic protein levels in a mouse model of Alzheimer's disease
    • doi: 10.1371/journal.pone.0017669
    • Adlard PA, Bica L, White AR, Nurjono M, Filiz G, et al. (2011) Metal ionophore treatment restores dendritic spine density and synaptic protein levels in a mouse model of Alzheimer's disease. PLOS ONE 6: e17669. doi:10.1371/journal.pone.0017669. PubMed: 21412423.
    • (2011) PLOS ONE , vol.6
    • Adlard, P.A.1    Bica, L.2    White, A.R.3    Nurjono, M.4    Filiz, G.5
  • 67
    • 33746079643 scopus 로고    scopus 로고
    • Different dendrite and dendritic spine alterations in basal and apical arbors in mutant human amyloid precursor protein transgenic mice
    • doi: 10.1016/j.brainres.2006.04.109
    • Alpár A, Ueberham U, Brückner MK, Seeger G, Arendt T, et al. (2006) Different dendrite and dendritic spine alterations in basal and apical arbors in mutant human amyloid precursor protein transgenic mice. Brain Res 1099: 189-198. doi:10.1016/j.brainres.2006.04.109. PubMed: 16781686.
    • (2006) Brain Res , vol.1099 , pp. 189-198
    • Alpár, A.1    Ueberham, U.2    Brückner, M.K.3    Seeger, G.4    Arendt, T.5
  • 68
    • 33645520634 scopus 로고    scopus 로고
    • Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease
    • doi: 10.1073/pnas.0600948103
    • Jacobsen JS, Wu CC, Redwine JM, Comery TA, Arias R, et al. (2006) Early-onset behavioral and synaptic deficits in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 103: 5161-5166. doi:10.1073/pnas.0600948103. PubMed: 16549764.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 5161-5166
    • Jacobsen, J.S.1    Wu, C.C.2    Redwine, J.M.3    Comery, T.A.4    Arias, R.5
  • 69
    • 0043095312 scopus 로고    scopus 로고
    • Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype
    • doi: 10.1016/S0969-9961(03)00079-2
    • Lanz TA, Carter DB, Merchant KM, (2003) Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype. Neurobiol Dis 13: 246-253. doi:10.1016/S0969-9961(03)00079-2. PubMed: 12901839.
    • (2003) Neurobiol Dis , vol.13 , pp. 246-253
    • Lanz, T.A.1    Carter, D.B.2    Merchant, K.M.3
  • 70
    • 79952401018 scopus 로고    scopus 로고
    • Reduced spine density in specific regions of CA1 pyramidal neurons in two transgenic mouse models of Alzheimer's disease
    • doi: 10.1523/JNEUROSCI.6142-10.2011
    • Perez-Cruz C, Nolte MW, van Gaalen MM, Rustay NR, Termont A, et al. (2011) Reduced spine density in specific regions of CA1 pyramidal neurons in two transgenic mouse models of Alzheimer's disease. J Neurosci 31: 3926-3934. doi:10.1523/JNEUROSCI.6142-10.2011. PubMed: 21389247.
    • (2011) J Neurosci , vol.31 , pp. 3926-3934
    • Perez-Cruz, C.1    Nolte, M.W.2    van Gaalen, M.M.3    Rustay, N.R.4    Termont, A.5
  • 71
    • 84881115847 scopus 로고    scopus 로고
    • Delayed dendritic development in newly generated dentate granule cells by cell-autonomous expression of the amyloid precursor protein
    • doi: 10.1016/j.mcn.2013.07.003
    • Morgenstern NA, Giacomini D, Lombardi G, Castaño EM, Schinder AF, (2013) Delayed dendritic development in newly generated dentate granule cells by cell-autonomous expression of the amyloid precursor protein. Mol Cell Neurosci 56: 298-306. doi:10.1016/j.mcn.2013.07.003. PubMed: 23851186.
    • (2013) Mol Cell Neurosci , vol.56 , pp. 298-306
    • Morgenstern, N.A.1    Giacomini, D.2    Lombardi, G.3    Castaño, E.M.4    Schinder, A.F.5
  • 72
    • 77950459972 scopus 로고    scopus 로고
    • Hippocampal interneuron loss in an APP/PS1 double mutant mouse and in Alzheimer's disease
    • doi: 10.1007/s00429-010-0242-4
    • Takahashi H, Brasnjevic I, Rutten BP, Van Der Kolk N, Perl DP, et al. (2010) Hippocampal interneuron loss in an APP/PS1 double mutant mouse and in Alzheimer's disease. Brain Struct Funct 214: 145-160. doi:10.1007/s00429-010-0242-4. PubMed: 20213270.
    • (2010) Brain Struct Funct , vol.214 , pp. 145-160
    • Takahashi, H.1    Brasnjevic, I.2    Rutten, B.P.3    Van Der Kolk, N.4    Perl, D.P.5
  • 73
    • 84865801305 scopus 로고    scopus 로고
    • Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision
    • doi: 10.1038/nature11306
    • Song J, Zhong C, Bonaguidi MA, Sun GJ, Hsu D, et al. (2012) Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision. Nature 489: 150-154. doi:10.1038/nature11306. PubMed: 22842902.
    • (2012) Nature , vol.489 , pp. 150-154
    • Song, J.1    Zhong, C.2    Bonaguidi, M.A.3    Sun, G.J.4    Hsu, D.5
  • 74
    • 80255127361 scopus 로고    scopus 로고
    • Neurogenesis, cellular plasticity and cognition: the impact of stem cells in the adult and aging brain- a mini-review
    • doi: 10.1159/000323481
    • Couillard-Despres S, Iglseder B, Aigner L, (2011) Neurogenesis, cellular plasticity and cognition: the impact of stem cells in the adult and aging brain- a mini-review. Gerontology 57: 559-564. doi:10.1159/000323481. PubMed: 21311170.
    • (2011) Gerontology , vol.57 , pp. 559-564
    • Couillard-Despres, S.1    Iglseder, B.2    Aigner, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.