-
1
-
-
0033105414
-
Regulation of JNK signaling by GSTp
-
Adler V, Funchs SY, Benezra M, Rosario L, Tew KD, Pincus MR, Sardana M, Henderson CJ, Wolf CR, Davis RJ, and Ronai Z. Regulation of JNK signaling by GSTp. EMBO J 18: 1321-1234, 1999.
-
(1999)
EMBO J
, vol.18
, pp. 1321-1234
-
-
Adler, V.1
Funchs, S.Y.2
Benezra, M.3
Rosario, L.4
Tew, K.D.5
Pincus, M.R.6
Sardana, M.7
Henderson, C.J.8
Wolf, C.R.9
Davis, R.J.10
Ronai, Z.11
-
2
-
-
0034708832
-
The c-Jun NH 2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of ser 307
-
Aguirre V, Uchida T, Yenush L, Davis R, and White MF. The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307). J Biol Chem 275: 9047-9054, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 9047-9054
-
-
Aguirre, V.1
Uchida, T.2
Yenush, L.3
Davis, R.4
White, M.F.5
-
3
-
-
80054850136
-
Increase in Trx2/Prx3 redox system immunoreactivity in the spinal cord and hippocampus of aged dogs
-
Ahn JH, Choi JH, Song JM, Lee CH, Yoo KY, Hwang IK, Kim JS, Shin HC, and Won MH. Increase in Trx2/Prx3 redox system immunoreactivity in the spinal cord and hippocampus of aged dogs. Exp Gerontol 46: 946-952, 2011.
-
(2011)
Exp Gerontol
, vol.46
, pp. 946-952
-
-
Ahn, J.H.1
Choi, J.H.2
Song, J.M.3
Lee, C.H.4
Yoo, K.Y.5
Hwang, I.K.6
Kim, J.S.7
Shin, H.C.8
Won, M.H.9
-
4
-
-
12344335482
-
Long-lived growth hormone receptor knockout mice: Interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction
-
Al-Regaiey KA, Masternak MM, Bonkowski M, Sun L, and Bartke A. Long-lived growth hormone receptor knockout mice: interaction of reduced insulin-like growth factor i/insulin signaling and caloric restriction. Endocrinology 146: 851-860, 2005.
-
(2005)
Endocrinology
, vol.146
, pp. 851-860
-
-
Al-Regaiey, K.A.1
Masternak, M.M.2
Bonkowski, M.3
Sun, L.4
Bartke, A.5
-
5
-
-
69949102009
-
PGC-1alpha in aging and antiaging interventions
-
Anderson R and Prolla T. PGC-1alpha in aging and antiaging interventions. Biochim Biophys Acta 1790: 1059-1066, 2009.
-
(2009)
Biochim Biophys Acta
, vol.1790
, pp. 1059-1066
-
-
Anderson, R.1
Prolla, T.2
-
6
-
-
38349130508
-
Dynamic regulation of PGC-1alpha localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response
-
Anderson RM, Barger JL, Edwards MG, Braun KH, OConnor CE, Prolla TA, and Weindruch R. Dynamic regulation of PGC-1alpha localization and turnover implicates mitochondrial adaptation in calorie restriction and the stress response. Aging Cell 7: 101-111, 2008.
-
(2008)
Aging Cell
, vol.7
, pp. 101-111
-
-
Anderson, R.M.1
Barger, J.L.2
Edwards, M.G.3
Braun, K.H.4
Oconnor, C.E.5
Prolla, T.A.6
Weindruch, R.7
-
7
-
-
70449568292
-
Akt1 intramitochondrial cycling is a crucial step in the redox modulation of cell cycle progression
-
Antico Arciuch VG, Galli S, Franco MC, Lam PY, Cadenas E, Carreras MC, and Poderoso JJ. Akt1 intramitochondrial cycling is a crucial step in the redox modulation of cell cycle progression. PLoS One 4: e7523, 2009.
-
(2009)
PLoS One
, vol.4
-
-
Antico Arciuch, V.G.1
Galli, S.2
Franco, M.C.3
Lam, P.Y.4
Cadenas, E.5
Carreras, M.C.6
Poderoso, J.J.7
-
8
-
-
0033582933
-
Bridge over troubled waters: Sensing stress by disulfide bond formation
-
Aslund F and Beckwith J. Bridge over troubled waters: sensing stress by disulfide bond formation. Cell 96: 751-753, 1999.
-
(1999)
Cell
, vol.96
, pp. 751-753
-
-
Aslund, F.1
Beckwith, J.2
-
9
-
-
34548133215
-
2nd Mechanisms of mitochondrial dysfunction and energy deficiency in Alzheimers disease
-
Atamna H and Frey WH, 2nd. Mechanisms of mitochondrial dysfunction and energy deficiency in Alzheimers disease. Mitochondrion 7: 297-310, 2007.
-
(2007)
Mitochondrion
, vol.7
, pp. 297-310
-
-
Atamna, H.1
Frey, W.H.2
-
10
-
-
18244386217
-
Endogenous hydrogen peroxide regulates the excitability of midbrain dopamine neurons via ATP-sensitive potassium channels
-
Avshalumov MV, Chen BT, Koos T, Tepper JM, and Rice ME. Endogenous hydrogen peroxide regulates the excitability of midbrain dopamine neurons via ATP-sensitive potassium channels. J Neurosci 25: 4222-4231, 2005.
-
(2005)
J Neurosci
, vol.25
, pp. 4222-4231
-
-
Avshalumov, M.V.1
Chen, B.T.2
Koos, T.3
Tepper, J.M.4
Rice, M.E.5
-
11
-
-
0037390413
-
Glutamate-dependent inhibition of dopamine release in striatum is mediated by a new diffusible messenger, H2O2
-
Avshalumov MV, Chen BT, Marshall SP, Pena DM, and Rice ME. Glutamate-dependent inhibition of dopamine release in striatum is mediated by a new diffusible messenger, H2O2. J Neurosci 23: 2744-2750, 2003.
-
(2003)
J Neurosci
, vol.23
, pp. 2744-2750
-
-
Avshalumov, M.V.1
Chen, B.T.2
Marshall, S.P.3
Pena, D.M.4
Rice, M.E.5
-
12
-
-
0141482021
-
Activation of ATP-sensitive K+ (K(ATP)) channels by H2O2 underlies glutamatedependent inhibition of striatal dopamine release
-
Avshalumov MV and Rice ME. Activation of ATP-sensitive K+ (K(ATP)) channels by H2O2 underlies glutamatedependent inhibition of striatal dopamine release. Proc Natl Acad Sci U S A 100: 11729-11734, 2003.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 11729-11734
-
-
Avshalumov, M.V.1
Rice, M.E.2
-
13
-
-
0037593949
-
Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity
-
Bach D, Pich S, Soriano FX, Vega N, Baumgartner B, Oriola J, Daugaard JR, Lloberas J, Camps M, Zierath JR, Rabasa-Lhoret R, Wallberg-Henriksson H, Laville M, Palacin M, Vidal H, Rivera F, Brand M, and Zorzano A. Mitofusin-2 determines mitochondrial network architecture and mitochondrial metabolism. A novel regulatory mechanism altered in obesity. J Biol Chem 278: 17190-17197, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 17190-17197
-
-
Bach, D.1
Pich, S.2
Soriano, F.X.3
Vega, N.4
Baumgartner, B.5
Oriola, J.6
Daugaard, J.R.7
Lloberas, J.8
Camps, M.9
Zierath, J.R.10
Rabasa-Lhoret, R.11
Wallberg-Henriksson, H.12
Laville, M.13
Palacin, M.14
Vidal, H.15
Rivera, F.16
Brand, M.17
Zorzano, A.18
-
14
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
Balaban RS, Nemoto S, and Finkel T. Mitochondria, oxidants, and aging. Cell 120: 483-495, 2005.
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
15
-
-
67650708614
-
Mitochondria are the source of hydrogen peroxide for dynamic brain cell signaling
-
Bao L, Avshalumov MV, Patel JC, Lee CR, Miller EW, Chang CJ, and Rice ME. Mitochondria are the source of hydrogen peroxide for dynamic brain cell signaling. J Neurosci 29: 9002-9010, 2009.
-
(2009)
J Neurosci
, vol.29
, pp. 9002-9010
-
-
Bao, L.1
Avshalumov, M.V.2
Patel, J.C.3
Lee, C.R.4
Miller, E.W.5
Chang, C.J.6
Rice, M.E.7
-
16
-
-
27344450419
-
Partial mitochondrial inhibition causes striatal dopamine release suppression and medium spiny neuron depolarization via H2O2 elevation, not ATP depletion
-
Bao L, Avshalumov MV, and Rice ME. Partial mitochondrial inhibition causes striatal dopamine release suppression and medium spiny neuron depolarization via H2O2 elevation, not ATP depletion. J Neurosci 25: 10029-10040, 2005.
-
(2005)
J Neurosci
, vol.25
, pp. 10029-10040
-
-
Bao, L.1
Avshalumov, M.V.2
Rice, M.E.3
-
17
-
-
0036591972
-
Activation of GLUT1 by metabolic and osmotic stress: Potential involvement of AMP-Activated protein kinase (AMPK)
-
Barnes K, Ingram JC, Porras OH, Barros LF, Hudson ER, Fryer LG, Foufelle F, Carling D, Hardie DG, and Baldwin SA. Activation of GLUT1 by metabolic and osmotic stress: potential involvement of AMP-Activated protein kinase (AMPK). J Cell Sci 115: 2433-2442, 2002.
-
(2002)
J Cell Sci
, vol.115
, pp. 2433-2442
-
-
Barnes, K.1
Ingram, J.C.2
Porras, O.H.3
Barros, L.F.4
Hudson, E.R.5
Fryer, L.G.6
Foufelle, F.7
Carling, D.8
Hardie, D.G.9
Baldwin, S.A.10
-
19
-
-
0037423289
-
Negative regulation of mixed lineage kinase 3 by protein kinase B/ AKT leads to cell survival
-
Barthwal MK, Sathyanarayana P, Kundu CN, Rana B, Pradeep A, Sharma C, Woodgett JR, and Rana A. Negative regulation of mixed lineage kinase 3 by protein kinase B/ AKT leads to cell survival. J Biol Chem 278: 3897-3902, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 3897-3902
-
-
Barthwal, M.K.1
Sathyanarayana, P.2
Kundu, C.N.3
Rana, B.4
Pradeep, A.5
Sharma, C.6
Woodgett, J.R.7
Rana, A.8
-
20
-
-
0029125857
-
Aging, energy, and oxidative stress in neurodegenerative diseases
-
Beal MF. Aging, energy, and oxidative stress in neurodegenerative diseases. Ann Neurol 38: 357-366, 1995.
-
(1995)
Ann Neurol
, vol.38
, pp. 357-366
-
-
Beal, M.F.1
-
21
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman KB and Ames BN. The free radical theory of aging matures. Physiol Rev 78: 547-581, 1998.
-
(1998)
Physiol Rev
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
22
-
-
27844472159
-
Increased risk of Alzheimers disease in Type II diabetes: Insulin resistance of the brain or insulin-induced amyloid pathology?
-
Biessels GJ and Kappelle LJ. Increased risk of Alzheimers disease in Type II diabetes: insulin resistance of the brain or insulin-induced amyloid pathology? Biochem Soc Trans 33: 1041-1044, 2005.
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 1041-1044
-
-
Biessels, G.J.1
Kappelle, L.J.2
-
23
-
-
0346434149
-
Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation
-
Bijur GN and Jope RS. Rapid accumulation of Akt in mitochondria following phosphatidylinositol 3-kinase activation. J Neurochem 87: 1427-1435, 2003.
-
(2003)
J Neurochem
, vol.87
, pp. 1427-1435
-
-
Bijur, G.N.1
Jope, R.S.2
-
24
-
-
33745822021
-
The role of phospholipid hydroperoxide glutathione peroxidase isoforms in murine embryogenesis
-
Borchert A, Wang CC, Ufer C, Schiebel H, Savaskan NE, and Kuhn H. The role of phospholipid hydroperoxide glutathione peroxidase isoforms in murine embryogenesis. J Biol Chem 281: 19655-19664, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 19655-19664
-
-
Borchert, A.1
Wang, C.C.2
Ufer, C.3
Schiebel, H.4
Savaskan, N.E.5
Kuhn, H.6
-
25
-
-
0016681098
-
Mitochondrial production of superoxide anions and its relationship to the antimycininsensitive respiration
-
Boveris A and Cadenas E. Mitochondrial production of superoxide anions and its relationship to the antimycininsensitive respiration. FEBS Lett 54: 311-314, 1975.
-
(1975)
FEBS Lett
, vol.54
, pp. 311-314
-
-
Boveris, A.1
Cadenas, E.2
-
26
-
-
0034456720
-
Mitochondrial production of hydrogen peroxide regulation by nitric oxide and the role of ubisemiquinone
-
Boveris A and Cadenas E. Mitochondrial production of hydrogen peroxide regulation by nitric oxide and the role of ubisemiquinone. IUBMB Life 50: 245-250, 2000.
-
(2000)
IUBMB Life
, vol.50
, pp. 245-250
-
-
Boveris, A.1
Cadenas, E.2
-
27
-
-
0017154414
-
Role of ubiquinone in the mitochondrial generation of hydrogen peroxide
-
Boveris A, Cadenas E, and Stoppani AOM. Role of ubiquinone in the mitochondrial generation of hydrogen peroxide. Biochem J 156: 435-444, 1976.
-
(1976)
Biochem J
, vol.156
, pp. 435-444
-
-
Boveris, A.1
Cadenas, E.2
Aom, S.3
-
28
-
-
0015882341
-
The mitochondrial generation of hydrogen peroxide General properties and effect of hyperbaric oxygen
-
Boveris A and Chance B. The mitochondrial generation of hydrogen peroxide. General properties and effect of hyperbaric oxygen. Biochem J 134: 707-716, 1973.
-
(1973)
Biochem J
, vol.134
, pp. 707-716
-
-
Boveris, A.1
Chance, B.2
-
29
-
-
0001856250
-
The mitochondrial production of oxygen radicals and cellular aging
-
The Roles of Mitochondria, Free Radicals, and Antioxidants. Cadenas E and Packer L (Eds.) New York Marcel Dekker, Inc
-
Boveris A, Costa LE, and Cadenas E. The mitochondrial production of oxygen radicals and cellular aging. In: Understanding the Process of Aging. The Roles of Mitochondria, Free Radicals, and Antioxidants. Cadenas E and Packer L (Eds.). New York: Marcel Dekker, Inc.; 1999, pp.1-16.
-
(1999)
Understanding the Process of Aging
, pp. 1-16
-
-
Boveris, A.1
Costa, L.E.2
Cadenas, E.3
-
30
-
-
46349093995
-
Brain mitochondrial dysfunction in aging
-
Boveris A and Navarro A. Brain mitochondrial dysfunction in aging. IUBMB Life 60: 308-314, 2008.
-
(2008)
IUBMB Life
, vol.60
, pp. 308-314
-
-
Boveris, A.1
Navarro, A.2
-
31
-
-
0015363173
-
The cellular production of hydrogen peroxide
-
Boveris A, Oshino N, and Chance B. The cellular production of hydrogen peroxide. Biochem J 128: 617-630, 1972.
-
(1972)
Biochem J
, vol.128
, pp. 617-630
-
-
Boveris, A.1
Oshino, N.2
Chance, B.3
-
32
-
-
33745609228
-
Mitochondrial metabolic states regulate nitric oxide and hydrogen peroxide diffusion to the cytosol
-
Boveris A, Valdez LB, Zaobornyj T, and Bustamante J. Mitochondrial metabolic states regulate nitric oxide and hydrogen peroxide diffusion to the cytosol. Biochim Biophys Acta 1757: 535-542, 2006.
-
(2006)
Biochim Biophys Acta
, vol.1757
, pp. 535-542
-
-
Boveris, A.1
Valdez, L.B.2
Zaobornyj, T.3
Bustamante, J.4
-
33
-
-
0036244305
-
Nitric oxide and cell signaling pathways in mitochondrial dependent apoptosis
-
Boyd CS and Cadenas E. Nitric oxide and cell signaling pathways in mitochondrial dependent apoptosis. Biol Chem 383: 411-423, 2002.
-
(2002)
Biol Chem
, vol.383
, pp. 411-423
-
-
Boyd, C.S.1
Cadenas, E.2
-
34
-
-
79955591489
-
Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats
-
Braidy N, Guillemin GJ, Mansour H, Chan-Ling T, Poljak A, and Grant R. Age related changes in NAD+ metabolism oxidative stress and Sirt1 activity in wistar rats. PLoS One 6: e19194, 2011.
-
(2011)
PLoS One
, vol.6
-
-
Braidy, N.1
Guillemin, G.J.2
Mansour, H.3
Chan-Ling, T.4
Poljak, A.5
Grant, R.6
-
35
-
-
79954504166
-
Basic principles and emerging concepts in the redox control of transcription factors
-
Brigelius-Flohe R and Flohe L. Basic principles and emerging concepts in the redox control of transcription factors. Antioxid Redox Signal 15: 2335-2381, 2011.
-
(2011)
Antioxid Redox Signal
, vol.15
, pp. 2335-2381
-
-
Brigelius-Flohe, R.1
Flohe, L.2
-
36
-
-
0029161636
-
Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase
-
Brown GC. Nitric oxide regulates mitochondrial respiration and cell functions by inhibiting cytochrome oxidase. FEBS Lett 369: 136-139, 1995.
-
(1995)
FEBS Lett
, vol.369
, pp. 136-139
-
-
Brown, G.C.1
-
37
-
-
18244390483
-
Mitochondrial abnormalities in Alzheimer brain: Mechanistic implications
-
Bubber P, Haroutunian V, Fisch G, Blass J, and Gibson G. Mitochondrial abnormalities in Alzheimer brain: mechanistic implications. Ann Neurol 57: 695-703, 2005.
-
(2005)
Ann Neurol
, vol.57
, pp. 695-703
-
-
Bubber, P.1
Haroutunian, V.2
Fisch, G.3
Blass, J.4
Gibson, G.5
-
38
-
-
1642422773
-
Mitochondrial free radical production and cell signaling
-
Cadenas E. Mitochondrial free radical production and cell signaling. Mol Aspects Med 25: 17-26, 2004.
-
(2004)
Mol Aspects Med
, vol.25
, pp. 17-26
-
-
Cadenas, E.1
-
39
-
-
0017406503
-
Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria
-
Cadenas E, Boveris A, Ragan CI, and Stoppani AO. Production of superoxide radicals and hydrogen peroxide by NADH-ubiquinone reductase and ubiquinol-cytochrome c reductase from beef-heart mitochondria. Arch Biochem Biophys 180: 248-257, 1977.
-
(1977)
Arch Biochem Biophys
, vol.180
, pp. 248-257
-
-
Cadenas, E.1
Boveris, A.2
Ragan, C.I.3
Stoppani, A.O.4
-
40
-
-
33947606911
-
Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimers disease
-
Calabrese V, Sultana R, Scapagnini G, Guagliano E, Sapienza M, Bella R, Kanski J, Pennisi G, Mancuso C, Stella AM, and Butterfield DA. Nitrosative stress, cellular stress response, and thiol homeostasis in patients with Alzheimers disease. Antioxid Redox Signal 8: 1975-1986, 2006.
-
(2006)
Antioxid Redox Signal
, vol.8
, pp. 1975-1986
-
-
Calabrese, V.1
Sultana, R.2
Scapagnini, G.3
Guagliano, E.4
Sapienza, M.5
Bella, R.6
Kanski, J.7
Pennisi, G.8
Mancuso, C.9
Stella, A.M.10
Butterfield, D.A.11
-
41
-
-
64549127790
-
PGC-1alpha SIRT1 and AMPK, an energy sensing network that controls energy expenditure
-
Canto C and Auwerx J. PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure. Curr Opin Lipidol 20: 98-105, 2009.
-
(2009)
Curr Opin Lipidol
, vol.20
, pp. 98-105
-
-
Canto, C.1
Auwerx, J.2
-
42
-
-
67349276169
-
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
-
Canto C, Gerhart-Hines Z, Feige JN, Lagouge M, Noriega L, Milne JC, Elliott PJ, Puigserver P, and Auwerx J. AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. Nature 458: 1056-1060, 2009.
-
(2009)
Nature
, vol.458
, pp. 1056-1060
-
-
Canto, C.1
Gerhart-Hines, Z.2
Feige, J.N.3
Lagouge, M.4
Noriega, L.5
Milne, J.C.6
Elliott, P.J.7
Puigserver, P.8
Auwerx, J.9
-
43
-
-
36048945306
-
Regulation of mitochondrial fusion and division
-
Cerveny KL, Tamura Y, Zhang Z, Jensen RE, and Sesaki H. Regulation of mitochondrial fusion and division. Trends Cell Biol 17: 563-569, 2007.
-
(2007)
Trends Cell Biol
, vol.17
, pp. 563-569
-
-
Cerveny, K.L.1
Tamura, Y.2
Zhang, Z.3
Jensen, R.E.4
Sesaki, H.5
-
44
-
-
33745274726
-
Mitochondria: Dynamic organelles in disease, aging, and development
-
Chan DC. Mitochondria: dynamic organelles in disease, aging, and development. Cell 125: 1241-1252, 2006.
-
(2006)
Cell
, vol.125
, pp. 1241-1252
-
-
Chan, D.C.1
-
45
-
-
77049233362
-
Respiratory enzymes in oxidative phosphorylation
-
Chance B and Williams GR. Respiratory enzymes in oxidative phosphorylation. J Biol Chem 217: 383-427, 1955.
-
(1955)
J Biol Chem
, vol.217
, pp. 383-427
-
-
Chance, B.1
Williams, G.R.2
-
46
-
-
4744373181
-
Peroxiredoxin III a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria
-
Chang TS, Cho CS, Park S, Yu S, Kang SW, and Rhee SG. Peroxiredoxin III, a mitochondrion-specific peroxidase, regulates apoptotic signaling by mitochondria. J Biol Chem 279: 41975-41984, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 41975-41984
-
-
Chang, T.S.1
Cho, C.S.2
Park, S.3
Yu, S.4
Kang, S.W.5
Rhee, S.G.6
-
47
-
-
77951096150
-
Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases
-
Chen H and Chan DC. Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases. Hum Mol Genet 18: R169-R176, 2009.
-
(2009)
Hum Mol Genet
, vol.18
-
-
Chen, H.1
Chan, D.C.2
-
48
-
-
77955287381
-
Physiological functions of mitochondrial fusion
-
Chen H and Chan DC. Physiological functions of mitochondrial fusion. Ann N Y Acad Sci 1201: 21-25, 2010.
-
(2010)
Ann N y Acad Sci
, vol.1201
, pp. 21-25
-
-
Chen, H.1
Chan, D.C.2
-
49
-
-
56849124393
-
Reduction of mitochondrial H2O2 by overexpressing peroxiredoxin 3 improves glucose tolerance in mice
-
Chen L, Na R, Gu M, Salmon AB, Liu Y, Liang H, Qi W, Van Remmen H, Richardson A, and Ran Q. Reduction of mitochondrial H2O2 by overexpressing peroxiredoxin 3 improves glucose tolerance in mice. Aging Cell 7: 866-878, 2008.
-
(2008)
Aging Cell
, vol.7
, pp. 866-878
-
-
Chen, L.1
Na, R.2
Gu, M.3
Salmon, A.B.4
Liu, Y.5
Liang, H.6
Qi, W.7
Van Remmen, H.8
Richardson, A.9
Ran, Q.10
-
50
-
-
36349016509
-
Mitochondrial complex II in the post-ischemic heart: Oxidative injury and the role of protein S-glutathionylation
-
Chen YR, Chen CL, Pfeiffer DR, and Zweier JL. Mitochondrial complex II in the post-ischemic heart: oxidative injury and the role of protein S-glutathionylation. J Biol Chem 282: 32640-32654, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 32640-32654
-
-
Chen, Y.R.1
Chen, C.L.2
Pfeiffer, D.R.3
Zweier, J.L.4
-
51
-
-
77957229010
-
Insulin signaling meets mitochondria in metabolism
-
Cheng Z, Tseng Y, and White MF. Insulin signaling meets mitochondria in metabolism. Trends Endocrinol Metab 21: 589-598, 2010.
-
(2010)
Trends Endocrinol Metab
, vol.21
, pp. 589-598
-
-
Cheng, Z.1
Tseng, Y.2
White, M.F.3
-
52
-
-
64249133725
-
S-nitrosylation of Drp1 mediates betaamyloid-related mitochondrial fission and neuronal injury
-
Cho DH, Nakamura T, Fang J, Cieplak P, Godzik A, Gu Z, and Lipton SA. S-nitrosylation of Drp1 mediates betaamyloid-related mitochondrial fission and neuronal injury. Science 324: 102-105, 2009.
-
(2009)
Science
, vol.324
, pp. 102-105
-
-
Cho, D.H.1
Nakamura, T.2
Fang, J.3
Cieplak, P.4
Godzik, A.5
Gu, Z.6
Lipton, S.A.7
-
53
-
-
77957358299
-
Mitochondrial dynamics in cell death and neurodegeneration
-
Cho DH, Nakamura T, and Lipton SA. Mitochondrial dynamics in cell death and neurodegeneration. Cell Mol Life Sci 67: 3435-3447, 2010.
-
(2010)
Cell Mol Life Sci
, vol.67
, pp. 3435-3447
-
-
Cho, D.H.1
Nakamura, T.2
Lipton, S.A.3
-
54
-
-
72649107570
-
Transgenic mouse models for the vital selenoenzymes cytosolic thioredoxin reductase, mitochondrial thioredoxin reductase, and glutathione peroxidase 4
-
Conrad M. Transgenic mouse models for the vital selenoenzymes cytosolic thioredoxin reductase, mitochondrial thioredoxin reductase, and glutathione peroxidase 4. Biochim Biophys Acta 1790: 1575-1585, 2009.
-
(2009)
Biochim Biophys Acta
, vol.1790
, pp. 1575-1585
-
-
Conrad, M.1
-
55
-
-
77956308889
-
Angiotensin II inhibits insulin-stimulated GLUT4 translocation and Akt activation through tyrosine nitration-dependent mechanisms
-
Csibi A, Communi D, Muller N, and Bottari SP. Angiotensin II inhibits insulin-stimulated GLUT4 translocation and Akt activation through tyrosine nitration-dependent mechanisms. PLoS One 5: e10070, 2010.
-
(2010)
PLoS One
, vol.5
-
-
Csibi, A.1
Communi, D.2
Muller, N.3
Bottari, S.P.4
-
56
-
-
33749042331
-
Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration
-
Cui L, Jeong H, Borovecki F, Parkhurst CN, Tanese N, and Krainc D. Transcriptional repression of PGC-1alpha by mutant huntingtin leads to mitochondrial dysfunction and neurodegeneration. Cell 127: 59-69, 2006.
-
(2006)
Cell
, vol.127
, pp. 59-69
-
-
Cui, L.1
Jeong, H.2
Borovecki, F.3
Parkhurst, C.N.4
Tanese, N.5
Krainc, D.6
-
57
-
-
2542469551
-
Protein disulfide bond formation in the cytoplasm during oxidative stress
-
Cumming RC, Andon NL, Haynes PA, Park M, Fischer WH, and Schubert D. Protein disulfide bond formation in the cytoplasm during oxidative stress. J Biol Chem 279: 21749-21758, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 21749-21758
-
-
Cumming, R.C.1
Andon, N.L.2
Haynes, P.A.3
Park, M.4
Fischer, W.H.5
Schubert, D.6
-
58
-
-
36749081539
-
MTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex
-
Cunningham JT, Rodgers JT, Arlow DH, Vazquez F, Mootha VK, and Puigserver P. mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex. Nature 450: 736-740, 2007.
-
(2007)
Nature
, vol.450
, pp. 736-740
-
-
Cunningham, J.T.1
Rodgers, J.T.2
Arlow, D.H.3
Vazquez, F.4
Mootha, V.K.5
Puigserver, P.6
-
59
-
-
0035028296
-
Functional imaging in Parkinsons disease
-
Dagher A. Functional imaging in Parkinsons disease. Semin Neurol 21: 23-32, 2001.
-
(2001)
Semin Neurol
, vol.21
, pp. 23-32
-
-
Dagher, A.1
-
60
-
-
79956088578
-
Inorganic nitrate therapy improves Doxorubicin-induced cardiomyopathy a new window for an affordable cardiovascular therapy for everyone?
-
Daiber A, Gori T, and Munzel T. Inorganic nitrate therapy improves Doxorubicin-induced cardiomyopathy a new window for an affordable cardiovascular therapy for everyone? J Am Coll Cardiol 57: 2190-2193, 2011.
-
(2011)
J Am Coll Cardiol
, vol.57
, pp. 2190-2193
-
-
Daiber, A.1
Gori, T.2
Munzel, T.3
-
61
-
-
78650152892
-
S-glutathiolation in life and death decisions of the cell
-
Dalle-Donne I, Colombo G, Gagliano N, Colombo R, Giustarini D, Rossi R, and Milzani A. S-glutathiolation in life and death decisions of the cell. Free Radic Res 45: 3-15, 2011.
-
(2011)
Free Radic Res
, vol.45
, pp. 3-15
-
-
Dalle-Donne, I.1
Colombo, G.2
Gagliano, N.3
Colombo, R.4
Giustarini, D.5
Rossi, R.6
Milzani, A.7
-
62
-
-
38349016262
-
Molecular mechanisms and potential clinical significance of S-glutathionylation
-
Dalle-Donne I, Milzani A, Gagliano N, Colombo R, Giustarini D, and Rossi R. Molecular mechanisms and potential clinical significance of S-glutathionylation. Antioxid Redox Signal 10: 445-473, 2008.
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 445-473
-
-
Dalle-Donne, I.1
Milzani, A.2
Gagliano, N.3
Colombo, R.4
Giustarini, D.5
Rossi, R.6
-
63
-
-
40849133786
-
Silencing of peroxiredoxin 3 and peroxiredoxin 5 reveals the role of mitochondrial peroxiredoxins in the protection of human neuroblastoma SH-SY5Y cells toward MPP+
-
De Simoni S, Goemaere J, and Knoops B. Silencing of peroxiredoxin 3 and peroxiredoxin 5 reveals the role of mitochondrial peroxiredoxins in the protection of human neuroblastoma SH-SY5Y cells toward MPP+ . Neurosci Lett 433: 219-224, 2008.
-
(2008)
Neurosci Lett
, vol.433
, pp. 219-224
-
-
De Simoni, S.1
Goemaere, J.2
Knoops, B.3
-
64
-
-
0035798097
-
TOR a homeostatic ATP sensor
-
Dennis PB, Jaeschke A, Saitoh M, Fowler B, Kozma SC, and Thomas G. Mammalian TOR: a homeostatic ATP sensor. Science 294: 1102-1105, 2001.
-
(2001)
Science
, vol.294
, pp. 1102-1105
-
-
Dennis, P.B.1
Jaeschke, A.2
Saitoh, M.3
Fowler, B.4
Kozma, S.C.5
Mammalian, T.G.6
-
65
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
Dinkova-Kostova AT, Holtzclaw WD, Cole RN, Itoh K, Wakabayashi N, Katoh Y, Yamamoto M, and Talalay P. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants. Proc Natl Acad Sci U S A 99: 11908-11913, 2002.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
Holtzclaw, W.D.2
Cole, R.N.3
Itoh, K.4
Wakabayashi, N.5
Katoh, Y.6
Yamamoto, M.7
Talalay, P.8
-
66
-
-
77956250065
-
Respiration-dependent H2O2 removal in brain mitochondria via the thioredoxin/ peroxiredoxin system
-
Drechsel DA and Patel M. Respiration-dependent H2O2 removal in brain mitochondria via the thioredoxin/ peroxiredoxin system. J Biol Chem 285: 27850-27858, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 27850-27858
-
-
Drechsel, D.A.1
Patel, M.2
-
67
-
-
0142063539
-
Method for measuring ATP production in isolated mitochondria: ATP production in brain and liver mitochondria of Fischer-344 rats with age and caloric restriction
-
Drew B and Leeuwenburgh C. Method for measuring ATP production in isolated mitochondria: ATP production in brain and liver mitochondria of Fischer-344 rats with age and caloric restriction. Am J Physiol Regul Integr Comp Physiol 285: R1259-R1267, 2003.
-
(2003)
Am J Physiol Regul Integr Comp Physiol
, vol.285
-
-
Drew, B.1
Leeuwenburgh, C.2
-
68
-
-
10344238130
-
Ageing and subcellular distribution of mitochondria: Role of mitochondrial DNA deletions and energy production
-
Drew B and Leeuwenburgh C. Ageing and subcellular distribution of mitochondria: role of mitochondrial DNA deletions and energy production. Acta Physiol Scand 182: 333-341, 2004.
-
(2004)
Acta Physiol Scand
, vol.182
, pp. 333-341
-
-
Drew, B.1
Leeuwenburgh, C.2
-
69
-
-
3342976149
-
Human peroxiredoxin 5 is a peroxynitrite reductase
-
Dubuisson M, Vander Stricht D, Clippe A, Etienne F, Nauser T, Kissner R, Koppenol WH, Rees JF, and Knoops B. Human peroxiredoxin 5 is a peroxynitrite reductase. FEBS Lett 571: 161-165, 2004.
-
(2004)
FEBS Lett
, vol.571
, pp. 161-165
-
-
Dubuisson, M.1
Vander Stricht, D.2
Clippe, A.3
Etienne, F.4
Nauser, T.5
Kissner, R.6
Koppenol, W.H.7
Rees, J.F.8
Knoops, B.9
-
70
-
-
33845976357
-
Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology
-
Duvezin-Caubet S, Jagasia R, Wagener J, Hofmann S, Trifunovic A, Hansson A, Chomyn A, Bauer MF, Attardi G, Larsson NG, Neupert W, and Reichert AS. Proteolytic processing of OPA1 links mitochondrial dysfunction to alterations in mitochondrial morphology. J Biol Chem 281: 37972-37979, 2006.
-
(2006)
J Biol Chem
, vol.281
, pp. 37972-37979
-
-
Duvezin-Caubet, S.1
Jagasia, R.2
Wagener, J.3
Hofmann, S.4
Trifunovic, A.5
Hansson, A.6
Chomyn, A.7
Bauer, M.F.8
Attardi, G.9
Larsson, N.G.10
Neupert, W.11
Reichert, A.S.12
-
71
-
-
41649119244
-
The malate-Aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restric-tion-mediated life span extension in yeast
-
Easlon E, Tsang F, Skinner C, Wang C, and Lin SJ. The malate-Aspartate NADH shuttle components are novel metabolic longevity regulators required for calorie restric-tion-mediated life span extension in yeast. Genes Dev 22: 931-944, 2008.
-
(2008)
Genes Dev
, vol.22
, pp. 931-944
-
-
Easlon, E.1
Tsang, F.2
Skinner, C.3
Wang, C.4
Lin, S.J.5
-
72
-
-
11844265406
-
Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release
-
Enoksson M, Fernandes AP, Prast S, Lillig CH, Holmgren A, and Orrenius S. Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release. Biochem Biophys Res Commun 327: 774-779, 2005.
-
(2005)
Biochem Biophys Res Commun
, vol.327
, pp. 774-779
-
-
Enoksson, M.1
Fernandes, A.P.2
Prast, S.3
Lee, C.H.4
Holmgren, A.5
Orrenius, S.6
-
73
-
-
0035209380
-
Metabolic network abnormalities in early Huntingtons disease: An [(18)F]FDG PET study
-
Feigin A, Leenders KL, Moeller JR, Missimer J, Kuenig G, Spetsieris P, Antonini A, and Eidelberg D. Metabolic network abnormalities in early Huntingtons disease: an [(18)F]FDG PET study. J Nucl Med 42: 1591-1595, 2001.
-
(2001)
J Nucl Med
, vol.42
, pp. 1591-1595
-
-
Feigin, A.1
Leenders, K.L.2
Moeller, J.R.3
Missimer, J.4
Kuenig, G.5
Spetsieris, P.6
Antonini, A.7
Eidelberg, D.8
-
74
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
Finkel T and Holbrook NJ. Oxidants, oxidative stress and the biology of ageing. Nature 408: 239-247, 2000.
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
75
-
-
66049087696
-
The coordination of nuclear and mitochondrial communication during aging and calorie restriction
-
Finley LW and Haigis MC. The coordination of nuclear and mitochondrial communication during aging and calorie restriction. Ageing Res Rev 8: 173-188, 2009.
-
(2009)
Ageing Res Rev
, vol.8
, pp. 173-188
-
-
Finley, L.W.1
Haigis, M.C.2
-
76
-
-
1242272862
-
Identification and H2O2 sensitivity of the major constitutive MAPK phosphatase from rat brain
-
Foley TD, Armstrong JJ, and Kupchak BR. Identification and H2O2 sensitivity of the major constitutive MAPK phosphatase from rat brain. Biochem Biophys Res Commun 315: 568-574, 2004.
-
(2004)
Biochem Biophys Res Commun
, vol.315
, pp. 568-574
-
-
Foley, T.D.1
Armstrong, J.J.2
Kupchak, B.R.3
-
77
-
-
0035487808
-
The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis
-
Frank S, Gaume B, Bergmann-Leitner ES, Leitner WW, Robert EG, Catez F, Smith CL, and Youle RJ. The role of dynamin-related protein 1, a mediator of mitochondrial fission, in apoptosis. Dev Cell 1: 515-525, 2001.
-
(2001)
Dev Cell
, vol.1
, pp. 515-525
-
-
Frank, S.1
Gaume, B.2
Bergmann-Leitner, E.S.3
Leitner, W.W.4
Robert, E.G.5
Catez, F.6
Smith, C.L.7
Youle, R.J.8
-
78
-
-
18344390036
-
Identification by redox proteomics of glutathjionylated proteins in oxidatively stressed human T lymphocytes
-
Fratelli M, Demol H, Puype M, Casagrande S, Eberini I, Salmona M, Bonetto V, Mengozzi M, Duffieux F, Miclet E, Bachi A, Vandekerckhove J, Gianazza E, and Ghezzi P. Identification by redox proteomics of glutathjionylated proteins in oxidatively stressed human T lymphocytes. Proc Natl Acad Sci U S A 99: 3505-3510, 2002.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 3505-3510
-
-
Fratelli, M.1
Demol, H.2
Puype, M.3
Casagrande, S.4
Eberini, I.5
Salmona, M.6
Bonetto, V.7
Mengozzi, M.8
Duffieux, F.9
Miclet, E.10
Bachi, A.11
Vandekerckhove, J.12
Gianazza, E.13
Ghezzi, P.14
-
79
-
-
33645088824
-
Nicotinamide nucleotide transhydrogenase: A key role in insulin secretion
-
Freeman H, Shimomura K, Horner E, Cox RD, and Ashcroft FM. Nicotinamide nucleotide transhydrogenase: a key role in insulin secretion. Cell Metab 3: 35-45, 2006.
-
(2006)
Cell Metab
, vol.3
, pp. 35-45
-
-
Freeman, H.1
Shimomura, K.2
Horner, E.3
Cox, R.D.4
Ashcroft, F.M.5
-
80
-
-
77953357281
-
Ageing alters the supramolecular architecture of Ox-Phos complexes in rat brain cortex
-
Frenzel M, Rommelspacher H, Sugawa MD, and Dencher NA. Ageing alters the supramolecular architecture of Ox-Phos complexes in rat brain cortex. Exp Gerontol 45: 563-572, 2010.
-
(2010)
Exp Gerontol
, vol.45
, pp. 563-572
-
-
Frenzel, M.1
Rommelspacher, H.2
Sugawa, M.D.3
Dencher, N.A.4
-
81
-
-
15444339756
-
Brain insulin and insulin receptors in aging and sporadic Alzheimers disease
-
Frolich L, Blum-Degen D, Bernstein HG, Engelsberger S, Humrich J, Laufer S, Muschner D, Thalheimer A, Turk A, Hoyer S, Zochling R, Boissl KW, Jellinger K, and Riederer P. Brain insulin and insulin receptors in aging and sporadic Alzheimers disease. J Neural Transm 105: 423-438, 1998.
-
(1998)
J Neural Transm
, vol.105
, pp. 423-438
-
-
Frolich, L.1
Blum-Degen, D.2
Bernstein, H.G.3
Engelsberger, S.4
Humrich, J.5
Laufer, S.6
Muschner, D.7
Thalheimer, A.8
Turk, A.9
Hoyer, S.10
Zochling, R.11
Boissl, K.W.12
Jellinger, K.13
Riederer, P.14
-
82
-
-
78650068036
-
Regulation of mitochondrial glutathione redox status and protein glutathionylation by respiratory substrates
-
Garcia J, Han D, Sancheti H, Yap LP, Kaplowitz N, and Cadenas E. Regulation of mitochondrial glutathione redox status and protein glutathionylation by respiratory substrates. J Biol Chem 285: 39646-39654, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 39646-39654
-
-
Garcia, J.1
Han, D.2
Sancheti, H.3
Yap, L.P.4
Kaplowitz, N.5
Cadenas, E.6
-
83
-
-
71849095133
-
Cause and consequence: Mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-Associated neurodegenerative diseases
-
Gibson GE, Starkov A, Blass JP, Ratan RR, and Beal MF. Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-Associated neurodegenerative diseases. Biochim Biophys Acta 1802: 122-134, 2010.
-
(2010)
Biochim Biophys Acta
, pp. 122-134
-
-
Gibson, G.E.1
Starkov, A.2
Blass, J.P.3
Ratan, R.R.4
Beal, M.F.5
-
84
-
-
70349446460
-
Supercomplexes of the mitochondrial electron transport chain decline in the aging rat heart
-
Gomez LA, Monette JS, Chavez JD, Maier CS, and Hagen TM. Supercomplexes of the mitochondrial electron transport chain decline in the aging rat heart. Arch Biochem Biophys 490: 30-35, 2009.
-
(2009)
Arch Biochem Biophys
, vol.490
, pp. 30-35
-
-
Gomez, L.A.1
Monette, J.S.2
Chavez, J.D.3
Maier, C.S.4
Hagen, T.M.5
-
85
-
-
64449083797
-
Glutathione S-transferase p localizes in mitochondria and protects agains oxidative stress
-
Goto S, Kawakatsu M, Izumi S-i, Urata Y, Kageyama K, Ihara Y, Koji T, and Kondo T. Glutathione S-transferase p localizes in mitochondria and protects agains oxidative stress. Free Radic Biol Med 46: 1392-1403, 2009.
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 1392-1403
-
-
Goto, S.1
Kawakatsu, M.2
Izumi, S.-I.3
Urata, Y.4
Kageyama, K.5
Ihara, Y.6
Koji, T.7
Kondo, T.8
-
86
-
-
34848850156
-
An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. Elegans
-
Greer EL, Dowlatshahi D, Banko MR, Villen J, Hoang K, Blanchard D, Gygi SP, and Brunet A. An AMPK-FOXO pathway mediates longevity induced by a novel method of dietary restriction in C. elegans. Curr Biol 17: 1646-1656, 2007.
-
(2007)
Curr Biol
, vol.17
, pp. 1646-1656
-
-
Greer, E.L.1
Dowlatshahi, D.2
Banko, M.R.3
Villen, J.4
Hoang, K.5
Blanchard, D.6
Gygi, S.P.7
Brunet, A.8
-
87
-
-
0033231162
-
Biologic and pharmacologic regulation of mammalian glutathione synthesis
-
Griffith OW. Biologic and pharmacologic regulation of mammalian glutathione synthesis. Free Radic Biol Med 27: 922-935, 1999.
-
(1999)
Free Radic Biol Med
, vol.27
, pp. 922-935
-
-
Griffith, O.W.1
-
88
-
-
0001547757
-
Origin and turnover of mitochondrial glutathione
-
Griffith OW and Meister A. Origin and turnover of mitochondrial glutathione. Proc Natl Acad Sci U S A 82: 4668-4672, 1985.
-
(1985)
Proc Natl Acad Sci U S A
, vol.82
, pp. 4668-4672
-
-
Griffith, O.W.1
Meister, A.2
-
89
-
-
0023022429
-
Decreased rate of ketone-body oxidation and decreased activity of D-3-hydroxybutyrate dehydrogenase and succinyl-CoA:3-oxo-Acid CoA-transferase in heart mitochondria of diabetic rats
-
Grinblat L, Pacheco Bolanos LF, and Stoppani AO. Decreased rate of ketone-body oxidation and decreased activity of D-3-hydroxybutyrate dehydrogenase and succinyl-CoA:3-oxo-Acid CoA-transferase in heart mitochondria of diabetic rats. Biochem J 240: 49-56, 1986.
-
(1986)
Biochem J
, vol.240
, pp. 49-56
-
-
Grinblat, L.1
Pacheco Bolanos, L.F.2
Stoppani, A.O.3
-
90
-
-
42949139481
-
AMPK phosphorylation of raptor mediates a metabolic checkpoint
-
Gwinn DM, Shackelford DB, Egan DF, Mihaylova MM, Mery A, Vasquez DS, Turk BE, and Shaw RJ. AMPK phosphorylation of raptor mediates a metabolic checkpoint. Mol Cell 30: 214-226, 2008.
-
(2008)
Mol Cell
, vol.30
, pp. 214-226
-
-
Gwinn, D.M.1
Shackelford, D.B.2
Egan, D.F.3
Mihaylova, M.M.4
Mery, A.5
Vasquez, D.S.6
Turk, B.E.7
Shaw, R.J.8
-
91
-
-
0037458619
-
Voltage-dependent anion channels control the release of superoxide anion from mitochondria to cytosol
-
Han D, Antunes F, Canali R, Rettori D, and Cadenas E. Voltage-dependent anion channels control the release of superoxide anion from mitochondria to cytosol. J Biol Chem 278: 5557-5563, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 5557-5563
-
-
Han, D.1
Antunes, F.2
Canali, R.3
Rettori, D.4
Cadenas, E.5
-
92
-
-
24644469955
-
Sites and mechanisms of aconitase inactivation by peroxynitrite: Modulation by citrate and glutathione
-
Han D, Canali R, Garcia J, Aguilera R, Gallaher TK, and Cadenas E. Sites and mechanisms of aconitase inactivation by peroxynitrite: modulation by citrate and glutathione. Biochemistry 44: 11986-11996, 2005.
-
(2005)
Biochemistry
, vol.44
, pp. 11986-11996
-
-
Han, D.1
Canali, R.2
Garcia, J.3
Aguilera, R.4
Gallaher, T.K.5
Cadenas, E.6
-
93
-
-
33845596500
-
Peroxisome proliferatoractivated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism
-
Handschin C and Spiegelman BM. Peroxisome proliferatoractivated receptor gamma coactivator 1 coactivators, energy homeostasis, and metabolism. Endocr Rev 27: 728-735, 2006.
-
(2006)
Endocr Rev
, vol.27
, pp. 728-735
-
-
Handschin, C.1
Spiegelman, B.M.2
-
94
-
-
79953193036
-
Sensing of energy and nutrients by AMPactivated protein kinase
-
Hardie DG. Sensing of energy and nutrients by AMPactivated protein kinase. Am J Clin Nutr 93: 891S-6, 2011.
-
(2011)
Am J Clin Nutr
, vol.93
-
-
Hardie, D.G.1
-
95
-
-
0036864358
-
Regulation of fatty acid synthesis and oxidation by the AMP-Activated protein kinase
-
Hardie DG and Pan DA. Regulation of fatty acid synthesis and oxidation by the AMP-Activated protein kinase. Biochem Soc Trans 30: 1064-1070, 2002.
-
(2002)
Biochem Soc Trans
, vol.30
, pp. 1064-1070
-
-
Hardie, D.G.1
Pan, D.A.2
-
96
-
-
0042731713
-
Mitochondrial peroxiredoxin-3 protects hippocampal neurons from excitotoxic injury in vivo
-
Hattori F, Murayama N, Noshita T, and Oikawa S. Mitochondrial peroxiredoxin-3 protects hippocampal neurons from excitotoxic injury in vivo. J Neurochem 86: 860-868, 2003.
-
(2003)
J Neurochem
, vol.86
, pp. 860-868
-
-
Hattori, F.1
Murayama, N.2
Noshita, T.3
Oikawa, S.4
-
97
-
-
33744955359
-
Caloric restriction protects mitochondrial function with aging in skeletal and cardiac muscles
-
Hepple RT, Baker DJ, McConkey M, Murynka T, and Norris R. Caloric restriction protects mitochondrial function with aging in skeletal and cardiac muscles. Rejuvenation Res 9: 219-222, 2006.
-
(2006)
Rejuvenation Res
, vol.9
, pp. 219-222
-
-
Hepple, R.T.1
Baker, D.J.2
McConkey, M.3
Murynka, T.4
Norris, R.5
-
98
-
-
46249128955
-
S-nitrosation and thiol switching in the mitochondrion: A new paradigm for cardioprotection in ischaemic preconditioning
-
Hill BG and Darley-Usmar VM. S-nitrosation and thiol switching in the mitochondrion: a new paradigm for cardioprotection in ischaemic preconditioning. Biochem J 412: e11-e13, 2008.
-
(2008)
Biochem J
, vol.412
-
-
Hill, B.G.1
Darley-Usmar, V.M.2
-
99
-
-
73249150574
-
Regulation of vascular smooth muscle cell bioenergetic function by protein glutathiolation
-
Hill BG, Higdon AN, Dranka BP, and Darley-Usmar VM. Regulation of vascular smooth muscle cell bioenergetic function by protein glutathiolation. Biochim Biophys Acta 1797: 285-295, 2010.
-
(2010)
Biochim Biophys Acta
, vol.1797
, pp. 285-295
-
-
Hill, B.G.1
Higdon, A.N.2
Dranka, B.P.3
Darley-Usmar, V.M.4
-
100
-
-
0023681148
-
Physiological roles of nicotinamide nucleotide transhydrogenase
-
Hoek JB and Rydstrom J. Physiological roles of nicotinamide nucleotide transhydrogenase. Biochem J 254: 1-10, 1988.
-
(1988)
Biochem J
, vol.254
, pp. 1-10
-
-
Hoek, J.B.1
Rydstrom, J.2
-
101
-
-
0024393963
-
Thioredoxin and glutaredoxin systems
-
Holmgren A. Thioredoxin and glutaredoxin systems. J Biol Chem 264: 13963-13966, 1989.
-
(1989)
J Biol Chem
, vol.264
, pp. 13963-13966
-
-
Holmgren, A.1
-
103
-
-
28844480498
-
Thiol redox control via thioredoxin and glutaredoxin systems
-
Holmgren A, Johansson C, Berndt C, Lonn ME, Hudemann C, and Lillig CH. Thiol redox control via thioredoxin and glutaredoxin systems. Biochem Soc Trans 33: 1375-1377, 2005.
-
(2005)
Biochem Soc Trans
, vol.33
, pp. 1375-1377
-
-
Holmgren, A.1
Johansson, C.2
Berndt, C.3
Lonn, M.E.4
Hudemann, C.5
Lillig, C.H.6
-
104
-
-
0036757263
-
The effect of aging on p38 signaling pathway activity in the mouse liver and in response to ROS generated by 3-nitropropionic acid
-
Hsieh CC and Papaconstantinou J. The effect of aging on p38 signaling pathway activity in the mouse liver and in response to ROS generated by 3-nitropropionic acid. Mech Ageing Dev 123: 1423-1435, 2002.
-
(2002)
Mech Ageing Dev
, vol.123
, pp. 1423-1435
-
-
Hsieh, C.C.1
Papaconstantinou, J.2
-
105
-
-
0037674756
-
Ageassociated changes in SAPK/JNK and p38 MAPK signaling in response to the generation of ROS by 3-nitropropionic acid
-
Hsieh CC, Rosenblatt JI, and Papaconstantinou J. Ageassociated changes in SAPK/JNK and p38 MAPK signaling in response to the generation of ROS by 3-nitropropionic acid. Mech Ageing Dev 124: 733-746, 2003.
-
(2003)
Mech Ageing Dev
, vol.124
, pp. 733-746
-
-
Hsieh, C.C.1
Rosenblatt, J.I.2
Papaconstantinou, J.3
-
106
-
-
33645128441
-
Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase
-
Huang TT, Naeemuddin M, and Elchuri S, Yamaguchi M, Kozy HM, Carlson EJ, and Epstein CJ. Genetic modifiers of the phenotype of mice deficient in mitochondrial superoxide dismutase. Hum Mol Genet 15: 1187-1194, 2006.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 1187-1194
-
-
Huang, T.T.1
Naeemuddin, M.2
Elchuri, S.3
Yamaguchi, M.4
Kozy, H.M.5
Carlson, E.J.6
Epstein, C.J.7
-
107
-
-
22044444687
-
Glutathionylation of mitochondrial proteins
-
Hurd TR, Costa NJ, Dahm CC, Beer SM, Brown SE, Filipovska A, and Murphy MP. Glutathionylation of mitochondrial proteins. Antioxid Redox Signal 7: 999-1010, 2005.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 999-1010
-
-
Hurd, T.R.1
Costa, N.J.2
Dahm, C.C.3
Beer, S.M.4
Brown, S.E.5
Filipovska, A.6
Murphy, M.P.7
-
108
-
-
77950341411
-
Changes in the expression of mitochondrial peroxiredoxin and thioredoxin in neurons and glia and their protective effects in experimental cerebral ischemic damage
-
Hwang IK, Yoo KY, Kim DW, Lee CH, Choi JH, Kwon YG, Kim YM, Choi SY, and Won MH. Changes in the expression of mitochondrial peroxiredoxin and thioredoxin in neurons and glia and their protective effects in experimental cerebral ischemic damage. Free Radic Biol Med 48: 1242-1251, 2010.
-
(2010)
Free Radic Biol Med
, vol.48
, pp. 1242-1251
-
-
Hwang, I.K.1
Yoo, K.Y.2
Kim, D.W.3
Lee, C.H.4
Choi, J.H.5
Kwon, Y.G.6
Kim, Y.M.7
Choi, S.Y.8
Won, M.H.9
-
109
-
-
0036368596
-
Loss in oxidative stress tolerance with aging linked to reduced extracellular signal-regulated kinase and Akt kinase activities
-
Ikeyama S, Kokkonen G, Shack S, Wang XT, and Holbrook NJ. Loss in oxidative stress tolerance with aging linked to reduced extracellular signal-regulated kinase and Akt kinase activities. FASEB J 16: 114-116, 2002.
-
(2002)
FASEB J
, vol.16
, pp. 114-116
-
-
Ikeyama, S.1
Kokkonen, G.2
Shack, S.3
Wang, X.T.4
Holbrook, N.J.5
-
110
-
-
68249087424
-
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
-
Ishihara N, Nomura M, Jofuku A, Kato H, Suzuki SO, Masuda K, Otera H, Nakanishi Y, Nonaka I, Goto Y, Taguchi N, Morinaga H, Maeda M, Takayanagi R, Yokota S, and Mihara K. Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice. Nat Cell Biol 11: 958-966, 2009.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 958-966
-
-
Ishihara, N.1
Nomura, M.2
Jofuku, A.3
Kato, H.4
Suzuki, S.O.5
Masuda, K.6
Otera, H.7
Nakanishi, Y.8
Nonaka, I.9
Goto, Y.10
Taguchi, N.11
Morinaga, H.12
Maeda, M.13
Takayanagi, R.14
Yokota, S.15
Mihara, K.16
-
111
-
-
34547545892
-
AMP-Activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha
-
Jager S, Handschin C, St-Pierre J, and Spiegelman BM. AMP-Activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc Natl Acad Sci U S A 104: 12017-12022, 2007.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 12017-12022
-
-
Jager, S.1
Handschin, C.2
St-Pierre, J.3
Spiegelman, B.M.4
-
112
-
-
34548274600
-
Mitofusin 2 protects cerebellar granule neurons against injury-induced cell death
-
Jahani-Asl A, Cheung EC, Neuspiel M, MacLaurin JG, Fortin A, Park DS, McBride HM, and Slack RS. Mitofusin 2 protects cerebellar granule neurons against injury-induced cell death. J Biol Chem 282: 23788-23798, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 23788-23798
-
-
Jahani-Asl, A.1
Cheung, E.C.2
Neuspiel, M.3
Maclaurin, J.G.4
Fortin, A.5
Park, D.S.6
McBride, H.M.7
Slack, R.S.8
-
113
-
-
79953019314
-
The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity
-
Jahani-Asl A, Pilon-Larose K, Xu W, MacLaurin JG, Park DS, McBride HM, and Slack RS. The mitochondrial inner membrane GTPase, optic atrophy 1 (Opa1), restores mitochondrial morphology and promotes neuronal survival following excitotoxicity. J Biol Chem 286: 4772-4782, 2011.
-
(2011)
J Biol Chem
, vol.286
, pp. 4772-4782
-
-
Jahani-Asl, A.1
Pilon-Larose, K.2
Xu, W.3
Maclaurin, J.G.4
Park, D.S.5
McBride, H.M.6
Slack, R.S.7
-
114
-
-
53049099984
-
Short-And long-term alterations of mitochondrial morphology, dynamics and mtDNA after transient oxidative stress
-
Jendrach M, Mai S, Pohl S, Voth M, and Bereiter-Hahn J. Short-And long-term alterations of mitochondrial morphology, dynamics and mtDNA after transient oxidative stress. Mitochondrion 8: 293-304, 2008.
-
(2008)
Mitochondrion
, vol.8
, pp. 293-304
-
-
Jendrach, M.1
Mai, S.2
Pohl, S.3
Voth, M.4
Bereiter-Hahn, J.5
-
115
-
-
21144434826
-
Characterization of neural cell types expressing peroxiredoxins in mouse brain
-
Jin MH, Lee YH, Kim JM, Sun HN, Moon EY, Shong MH, Kim SU, Lee SH, Lee TH, Yu DY, and Lee DS. Characterization of neural cell types expressing peroxiredoxins in mouse brain. Neurosci Lett 381: 252-257, 2005.
-
(2005)
Neurosci Lett
, vol.381
, pp. 252-257
-
-
Jin, M.H.1
Lee, Y.H.2
Kim, J.M.3
Sun, H.N.4
Moon, E.Y.5
Shong, M.H.6
Kim, S.U.7
Lee, S.H.8
Lee, T.H.9
Yu, D.Y.10
Lee, D.S.11
-
116
-
-
0036372619
-
Redox potential of GSH/GSSG couple: Assay and biological significance
-
Jones DP. Redox potential of GSH/GSSG couple: assay and biological significance. Methods Enzymol 348: 93-112, 2002.
-
(2002)
Methods Enzymol
, vol.348
, pp. 93-112
-
-
Jones, D.P.1
-
117
-
-
78149434112
-
The Nrf2 system as a potential target for the development of indirect antioxidants
-
Jung KA and Kwak MK. The Nrf2 system as a potential target for the development of indirect antioxidants. Molecules 15: 7266-7291, 2010.
-
(2010)
Molecules
, vol.15
, pp. 7266-7291
-
-
Jung, K.A.1
Kwak, M.K.2
-
118
-
-
20844451123
-
AMPactivated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
-
Kahn BB, Alquier T, Carling D, and Hardie DG. AMPactivated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab 1: 15-25, 2005.
-
(2005)
Cell Metab
, vol.1
, pp. 15-25
-
-
Kahn, B.B.1
Alquier, T.2
Carling, D.3
Hardie, D.G.4
-
119
-
-
28044457872
-
Oxidative stress and pancreatic beta-cell dysfunction
-
Kaneto H, Kawamori D, Matsuoka TA, Kajimoto Y, and Yamasaki Y. Oxidative stress and pancreatic beta-cell dysfunction. Am J Ther 12: 529-533, 2005.
-
(2005)
Am J Ther
, vol.12
, pp. 529-533
-
-
Kaneto, H.1
Kawamori, D.2
Matsuoka, T.A.3
Kajimoto, Y.4
Yamasaki, Y.5
-
120
-
-
78751566697
-
Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimers disease
-
Kapogiannis D and Mattson MP. Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimers disease. Lancet Neurol 10: 187-198, 2011.
-
(2011)
Lancet Neurol
, vol.10
, pp. 187-198
-
-
Kapogiannis, D.1
Mattson, M.P.2
-
121
-
-
27544450920
-
The role of Fis1p-Mdv1p interactions in mitochondrial fission complex assembly
-
Karren MA, Coonrod EM, Anderson TK, and Shaw JM. The role of Fis1p-Mdv1p interactions in mitochondrial fission complex assembly. J Cell Biol 171: 291-301, 2005.
-
(2005)
J Cell Biol
, vol.171
, pp. 291-301
-
-
Karrencoonrod, E.M.1
Anderson, T.K.2
Shaw, J.M.3
-
122
-
-
36549008295
-
Constitutive expression and functional characterization of mitochondrial glutaredoxin in mouse and human brain
-
Karunakaran S, Saeed U, Ramakrishnan S, Koumar RC, and Ravindranath V. Constitutive expression and functional characterization of mitochondrial glutaredoxin in mouse and human brain. Brain Res 1185: 8-17, 2007.
-
(2007)
Brain Res
, vol.1185
, pp. 8-17
-
-
Karunakaran, S.1
Saeed, U.2
Ramakrishnan, S.3
Koumar, R.C.4
Ravindranath, V.5
-
123
-
-
36248965746
-
Mitochondrial gene expression and increased oxidative metabolism: Role in increased lifespan of fat-specific insulin receptor knock-out mice
-
Katic M, Kennedy AR, Leykin I, Norris A, McGettrick A, Gesta S, Russell SJ, Bluher M, Maratos-Flier E, and Kahn CR. Mitochondrial gene expression and increased oxidative metabolism: role in increased lifespan of fat-specific insulin receptor knock-out mice. Aging Cell 6: 827-839, 2007.
-
(2007)
Aging Cell
, vol.6
, pp. 827-839
-
-
Katic, M.1
Kennedy, A.R.2
Leykin, I.3
Norris, A.4
McGettrick, A.5
Gesta, S.6
Russell, S.J.7
Bluher, M.8
Maratos-Flier, E.9
Kahn, C.R.10
-
124
-
-
39949085437
-
Nonequilibrium thermodynamics of thiol/disulfide redox systems: A perspective on redox systems biology
-
Kemp M, Go YM, and Jones DP. Nonequilibrium thermodynamics of thiol/disulfide redox systems: a perspective on redox systems biology. Free Radic Biol Med 44: 921-937, 2008.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 921-937
-
-
Kemp, M.1
Go, Y.M.2
Jones, D.P.3
-
125
-
-
0037390718
-
Glutaredoxin is essential for maintenance of brain mitochondrial complex I: Studies with MPTP
-
Kenchappa RS and Ravindranath V. Glutaredoxin is essential for maintenance of brain mitochondrial complex I: studies with MPTP. FASEB J 17: 717-719, 2003.
-
(2003)
FASEB J
, vol.17
, pp. 717-719
-
-
Kenchappa, R.S.1
Ravindranath, V.2
-
126
-
-
15444367716
-
Regulation of mitochondrial NADP+ -dependent isocitrate dehydrogenase activity by glutathionylation
-
Kil IS and Park JW. Regulation of mitochondrial NADP+ -dependent isocitrate dehydrogenase activity by glutathionylation. J Biol Chem 280: 10846-10854, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 10846-10854
-
-
Kil, I.S.1
Park, J.W.2
-
127
-
-
0036696560
-
Influence of aging and calorie restriction on MAPKs activity in rat kidney
-
Kim HJ, Jung KJ, Yu BP, Cho CG, and Chung HY. Influence of aging and calorie restriction on MAPKs activity in rat kidney. Exp Gerontol 37: 1041-1053, 2002.
-
(2002)
Exp Gerontol
, vol.37
, pp. 1041-1053
-
-
Kim, H.J.1
Jung, K.J.2
Yu, B.P.3
Cho, C.G.4
Chung, H.Y.5
-
128
-
-
0035233637
-
Protein levels of human peroxiredoxin subtypes in brains of patients with Alzheimers disease and Down syndrome
-
Kim SH, Fountoulakis M, Cairns N, and Lubec G. Protein levels of human peroxiredoxin subtypes in brains of patients with Alzheimers disease and Down syndrome. J Neural Transm Suppl: 223-235, 2001.
-
(2001)
J Neural Transm Suppl
, pp. 223-235
-
-
Kim, S.H.1
Fountoulakis, M.2
Cairns, N.3
Lubec, G.4
-
129
-
-
79955958990
-
Peroxiredoxin II preserves cognitive function against age-linked hippocampal oxidative damage
-
Kim SU, Jin MH, Kim YS, Lee SH, Cho YS, Cho KJ, Lee KS, Kim YI, Kim GW, Kim JM, Lee TH, Lee YH, Shong MH, Kim YC, Chang KT, Yu DY, and Lee DS. Peroxiredoxin II preserves cognitive function against age-linked hippocampal oxidative damage. Neurobiol Aging 32: 1054-1068, 2011.
-
(2011)
Neurobiol Aging
, vol.32
, pp. 1054-1068
-
-
Kim, S.U.1
Jin, M.H.2
Kim, Y.S.3
Lee, S.H.4
Cho, Y.S.5
Cho, K.J.6
Lee, K.S.7
Kim, Y.I.8
Kim, G.W.9
Kim, J.M.10
Lee, T.H.11
Lee, Y.H.12
Shong, M.H.13
Kim, Y.C.14
Chang, K.T.15
Yu, D.Y.16
Lee, D.S.17
-
130
-
-
0033869092
-
Regulation of protein function by Sglutathiolation in response to oxidative and nitrosative stress
-
Klatt P and Lamas S. Regulation of protein function by Sglutathiolation in response to oxidative and nitrosative stress. Eur J Biochem 267: 4928-4944, 2000.
-
(2000)
Eur J Biochem
, vol.267
, pp. 4928-4944
-
-
Klatt, P.1
Lamas, S.2
-
131
-
-
80555148138
-
Ionizing radiation accelerates Drp1-dependent mitochondrial fission, which involves delayed mitochondrial reactive oxygen species production in normal human fibroblast-like cells
-
Kobashigawa S, Suzuki K, and Yamashita S. Ionizing radiation accelerates Drp1-dependent mitochondrial fission, which involves delayed mitochondrial reactive oxygen species production in normal human fibroblast-like cells. Biochem Biophys Res Commun 414: 795-800, 2011.
-
(2011)
Biochem Biophys Res Commun
, vol.414
, pp. 795-800
-
-
Kobashigawa, S.1
Suzuki, K.2
Yamashita, S.3
-
132
-
-
0030729851
-
High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria
-
Korshunov SS, Skulachev VP, and Starkov AA. High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. FEBS Lett 416: 15-18, 1997.
-
(1997)
FEBS Lett
, vol.416
, pp. 15-18
-
-
Korshunov, S.S.1
Skulachev, V.P.2
Starkov, A.A.3
-
133
-
-
0344406145
-
Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders
-
Krapfenbauer K, Engidawork E, Cairns N, Fountoulakis M, and Lubec G. Aberrant expression of peroxiredoxin subtypes in neurodegenerative disorders. Brain Res 967: 152-160, 2003.
-
(2003)
Brain Res
, vol.967
, pp. 152-160
-
-
Krapfenbauer, K.1
Engidawork, E.2
Cairns, N.3
Fountoulakis, M.4
Lubec, G.5
-
134
-
-
0032765396
-
5 AMP-Activated protein kinase activation causes GLUT4 translocation in skeletal muscle
-
Kurth-Kraczek EJ, Hirshman MF, Goodyear LJ, and Winder WW.5 AMP-Activated protein kinase activation causes GLUT4 translocation in skeletal muscle. Diabetes 48: 1667-1671, 1999.
-
(1999)
Diabetes
, vol.48
, pp. 1667-1671
-
-
Kurth-Kraczek, E.J.1
Hirshman, M.F.2
Goodyear, L.J.3
Winder, W.W.4
-
135
-
-
0033958726
-
Age-related changes in activities of mitochondrial electron transport complexes in various tissues of the mouse
-
Kwong LK and Sohal RS. Age-related changes in activities of mitochondrial electron transport complexes in various tissues of the mouse. Arch Biochem Biophys 373: 16-22, 2000.
-
(2000)
Arch Biochem Biophys
, vol.373
, pp. 16-22
-
-
Kwong, L.K.1
Sohal, R.S.2
-
136
-
-
23844458007
-
Age-related changes in regional brain mitochondria from Fischer 344 rats
-
LaFrance R, Brustovetsky N, Sherburne C, Delong D, and Dubinsky JM. Age-related changes in regional brain mitochondria from Fischer 344 rats. Aging Cell 4: 139-145, 2005.
-
(2005)
Aging Cell
, vol.4
, pp. 139-145
-
-
Lafrance, R.1
Brustovetsky, N.2
Sherburne, C.3
Delong, D.4
Dubinsky, J.M.5
-
137
-
-
67650134121
-
Elevated neuronal nitric oxide synthase expression during ageing and mitochondrial energy production
-
Lam PY, Yin F, Hamilton RT, and Boveris A, Cadenas E. Elevated neuronal nitric oxide synthase expression during ageing and mitochondrial energy production. Free Radic Res 43: 431-439, 2009.
-
(2009)
Free Radic Res
, vol.43
, pp. 431-439
-
-
Lam, P.Y.1
Yin, F.2
Hamilton, R.T.3
Boveris, A.4
Cadenas, E.5
-
138
-
-
27544469820
-
Age-related changes in ATP-producing pathways in human skeletal muscle in vivo
-
Lanza IR, Befroy DE, and Kent-Braun JA. Age-related changes in ATP-producing pathways in human skeletal muscle in vivo. J Appl Physiol 99: 1736-1744, 2005.
-
(2005)
J Appl Physiol
, vol.99
, pp. 1736-1744
-
-
Lanza, I.R.1
Befroy, D.E.2
Kent-Braun, J.A.3
-
139
-
-
0032402945
-
Caloric restriction prevents age-Associated accrual of oxidative damage to mouse skeletal muscle mitochondria
-
Lass A, Sohal BH, Weindruch R, Forster MJ, and Sohal RS. Caloric restriction prevents age-Associated accrual of oxidative damage to mouse skeletal muscle mitochondria. Free Radic Biol Med 25: 1089-1097, 1998.
-
(1998)
Free Radic Biol Med
, vol.25
, pp. 1089-1097
-
-
Lass, A.1
Sohal, B.H.2
Weindruch, R.3
Forster, M.J.4
Sohal, R.S.5
-
140
-
-
78149470437
-
When neurogenesis encounters aging and disease
-
Lazarov O, Mattson MP, Peterson DA, Pimplikar SW, and van Praag H. When neurogenesis encounters aging and disease. Trends Neurosci 33: 569-579, 2010.
-
(2010)
Trends Neurosci
, vol.33
, pp. 569-579
-
-
Lazarov, O.1
Mattson, M.P.2
Peterson, D.A.3
Pimplikar, S.W.4
Van Praag, H.5
-
141
-
-
0029838063
-
Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice
-
Lebovitz RM, Zhang H, Vogel H, Cartwright J, Jr., Dionne L, Lu N, Huang S, and Matzuk MM. Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice. Proc Natl Acad Sci U S A 93: 9782-9787, 1996.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 9782-9787
-
-
Lebovitz, R.M.1
Zhang, H.2
Vogel, H.3
Cartwright Jr., J.4
Dionne, L.5
Lu, N.6
Huang, S.7
Matzuk, M.M.8
-
142
-
-
0033957373
-
Impaired signal transduction in mitogen activated rat splenic lymphocytes during aging
-
Li M, Walter R, Torres C, and Sierra F. Impaired signal transduction in mitogen activated rat splenic lymphocytes during aging. Mech Ageing Dev 113: 85-99, 2000.
-
(2000)
Mech Ageing Dev
, vol.113
, pp. 85-99
-
-
Li, M.1
Walter, R.2
Torres, C.3
Sierra, F.4
-
143
-
-
0028827252
-
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase
-
Li Y, Huang T-T, Carlson EJ, Melov S, Ursell PC, Olson JL, Noble LJ, Yoshimura MP, Berger C, Chan PH, Wallace DC, and Epstein CJ. Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase. Nature Genetics 11: 376-381, 1995.
-
(1995)
Nature Genetics
, vol.11
, pp. 376-381
-
-
Li, Y.1
Huang, T.-T.2
Carlson, E.J.3
Melov, S.4
Ursell, P.C.5
Olson, J.L.6
Noble, L.J.7
Yoshimura, M.P.8
Berger, C.9
Chan, P.H.10
Wallace, D.C.11
Epstein, C.J.12
-
144
-
-
67650868959
-
Mitochondrial dynamics in mammalian health and disease
-
Liesa M, Palacin M, and Zorzano A. Mitochondrial dynamics in mammalian health and disease. Physiol Rev 89: 799-845, 2009.
-
(2009)
Physiol Rev
, vol.89
, pp. 799-845
-
-
Liesa, M.1
Palacin, M.2
Zorzano, A.3
-
145
-
-
5344252327
-
Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice
-
Lin J, Wu PH, Tarr PT, Lindenberg KS, St-Pierre J, Zhang CY, Mootha VK, Jager S, Vianna CR, Reznick RM, Cui L, Manieri M, Donovan MX, Wu Z, Cooper MP, Fan MC, Rohas LM, Zavacki AM, Cinti S, Shulman GI, Lowell BB, Krainc D, and Spiegelman BM. Defects in adaptive energy metabolism with CNS-linked hyperactivity in PGC-1alpha null mice. Cell 119: 121-135, 2004.
-
(2004)
Cell
, vol.119
, pp. 121-135
-
-
Lin, J.1
Wu, P.H.2
Tarr, P.T.3
Lindenberg, K.S.4
St-Pierre, J.5
Zhang, C.Y.6
Mootha, V.K.7
Jager, S.8
Vianna, C.R.9
Reznick, R.M.10
Cui, L.11
Manieri, M.12
Donovan, M.X.13
Wu, Z.14
Cooper, M.P.15
Fan, M.C.16
Rohas, L.M.17
Zavacki, A.M.18
Cinti, S.19
Shulman, G.I.20
Lowell, B.B.21
Krainc, D.22
Spiegelman, B.M.23
more..
-
146
-
-
33750347347
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
Lin MT and Beal MF. Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443: 787-795, 2006.
-
(2006)
Nature
, vol.443
, pp. 787-795
-
-
Lin, M.T.1
Beal, M.F.2
-
147
-
-
67349120572
-
Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA-And ROS-dependent pathway
-
Liot G, Bossy B, Lubitz S, Kushnareva Y, Sejbuk N, and Bossy-Wetzel E. Complex II inhibition by 3-NP causes mitochondrial fragmentation and neuronal cell death via an NMDA-And ROS-dependent pathway. Cell Death Differ 16: 899-909, 2009.
-
(2009)
Cell Death Differ
, vol.16
, pp. 899-909
-
-
Liot, G.1
Bossy, B.2
Lubitz, S.3
Kushnareva, Y.4
Sejbuk, N.5
Bossy-Wetzel, E.6
-
148
-
-
0030049061
-
Age-related decline in mitogen-Activated protein kinase activity in epidermal growth factor-stimulated rat hepatocytes
-
Liu Y, Guyton KZ, Gorospe M, Xu Q, Kokkonen GC, Mock YD, Roth GS, and Holbrook NJ. Age-related decline in mitogen-Activated protein kinase activity in epidermal growth factor-stimulated rat hepatocytes. J Biol Chem 271: 3604-3607, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 3604-3607
-
-
Liu, Y.1
Guyton, K.Z.2
Gorospe, M.3
Xu, Q.4
Kokkonen, G.C.5
Mock, Y.D.6
Roth, G.S.7
Holbrook, N.J.8
-
149
-
-
12344305124
-
Mitochondrial dysfunction and type 2 diabetes
-
Lowell BB and Shulman GI. Mitochondrial dysfunction and type 2 diabetes. Science 307: 384-387, 2005.
-
(2005)
Science
, vol.307
, pp. 384-387
-
-
Lowell, B.B.1
Shulman, G.I.2
-
150
-
-
79959492723
-
Targeting mitochondrial oxidative stress in heart failure throttling the afterburner
-
Maack C and Bohm M. Targeting mitochondrial oxidative stress in heart failure throttling the afterburner. J Am Coll Cardiol 58: 83-86, 2011.
-
(2011)
J Am Coll Cardiol
, vol.58
, pp. 83-86
-
-
Maack, C.1
Bohm, M.2
-
151
-
-
0035877633
-
Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade
-
Mahadev K, Zilbering A, Zhu L, and Goldstein BJ. Insulin-stimulated hydrogen peroxide reversibly inhibits protein-tyrosine phosphatase 1b in vivo and enhances the early insulin action cascade. J Biol Chem 276: 21938-21942, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 21938-21942
-
-
Mahadev, K.1
Zilbering, A.2
Zhu, L.3
Goldstein, B.J.4
-
152
-
-
73449124480
-
Mitochondrial glutathione, a key survival antioxidant
-
Mar? M, Morales A, Colell A, Garc?a-Ruiz C, and Fernandez-Checa JC. Mitochondrial glutathione, a key survival antioxidant. Antioxid Redox Signal 11: 2685-2700, 2009.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2685-2700
-
-
Mar, M.1
Morales, A.2
Colell, A.3
Garca-Ruiz, C.4
Fernandez-Checa, J.C.5
-
153
-
-
0037163076
-
The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-Activated protein kinase and inducible 6-phosphofructo-2-kinase
-
Marsin AS, Bouzin C, Bertrand L, and Hue L. The stimulation of glycolysis by hypoxia in activated monocytes is mediated by AMP-Activated protein kinase and inducible 6-phosphofructo-2-kinase. J Biol Chem 277: 30778-30783, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 30778-30783
-
-
Marsin, A.S.1
Bouzin, C.2
Bertrand, L.3
Hue, L.4
-
155
-
-
57049143140
-
Mitochondria in neuroplasticity and neurological disorders
-
Mattson MP, Gleichmann M, and Cheng A. Mitochondria in neuroplasticity and neurological disorders. Neuron 60: 748-766, 2008.
-
(2008)
Neuron
, vol.60
, pp. 748-766
-
-
Mattson, M.P.1
Gleichmann, M.2
Cheng, A.3
-
156
-
-
33645299025
-
Ageing and neuronal vulnerability
-
Mattson MP and Magnus T. Ageing and neuronal vulnerability. Nat Rev Neurosci 7: 278-294, 2006.
-
(2006)
Nat Rev Neurosci
, vol.7
, pp. 278-294
-
-
Mattson, M.P.1
Magnus, T.2
-
157
-
-
33644855216
-
Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1
-
Maurer U, Charvet C, Wagman AS, Dejardin E, and Green DR. Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1. Mol Cell 21: 749-760, 2006.
-
(2006)
Mol Cell
, vol.21
, pp. 749-760
-
-
Maurer, U.1
Charvet, C.2
Wagman, A.S.3
Dejardin, E.4
Green, D.R.5
-
158
-
-
36448969497
-
Evolutionary conservation of regulated longevity assurance mechanisms
-
McElwee JJ, Schuster E, Blanc E, Piper MD, Thomas JH, Patel DS, Selman C, Wilthers DJ, Thornton JM, Partridge L, and Gems D. Evolutionary conservation of regulated longevity assurance mechanisms. Genome Biol 8: RI32, 2007.
-
(2007)
Genome Biol
, vol.8
-
-
McElwee, J.J.1
Schuster, E.2
Blanc, E.3
Piper, M.D.4
Thomas, J.H.5
Patel, D.S.6
Selman, C.7
Wilthers, D.J.8
Thornton, J.M.9
Partridge, L.10
Gems, D.11
-
159
-
-
38449083934
-
AMPK and transcriptional regulation
-
McGee SL and Hargreaves M. AMPK and transcriptional regulation. Front Biosci 13: 3022-3033, 2008.
-
(2008)
Front Biosci
, vol.13
, pp. 3022-3033
-
-
McGee, S.L.1
Hargreaves, M.2
-
160
-
-
42049121101
-
Ca2 + -operated transcriptional networks: Molecular mechanisms and in vivo models
-
Mellstrom B, Savignac M, Gomez-Villafuertes R, and Naranjo JR. Ca2 + -operated transcriptional networks: molecular mechanisms and in vivo models. Physiol Rev 88: 421-449, 2008.
-
(2008)
Physiol Rev
, vol.88
, pp. 421-449
-
-
Mellstrom, B.1
Savignac, M.2
Gomez-Villafuertes, R.3
Naranjo, J.R.4
-
161
-
-
0033912405
-
Mitochondrial oxidative stress Physiologic consequences and potential for a role in aging
-
Melov S. Mitochondrial oxidative stress. Physiologic consequences and potential for a role in aging. Ann N Y Acad Sci 908: 219-225, 2000.
-
(2000)
Ann N y Acad Sci
, vol.908
, pp. 219-225
-
-
Melov, S.1
-
162
-
-
84867730651
-
Protein-thiol oxidation and cell death: Regulatory role of glutaredoxins
-
Allen EM and Mieyal JJ. Protein-thiol oxidation and cell death: regulatory role of glutaredoxins. Antioxid Redox Signal, 17: 1748-1763, 2012.
-
(2012)
Antioxid Redox Signal
, vol.17
, pp. 1748-1763
-
-
Allen, E.M.1
Mieyal, J.J.2
-
164
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
Murphy MP. How mitochondria produce reactive oxygen species. Biochem J 417: 1-13, 2009.
-
(2009)
Biochem J
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
165
-
-
84856729192
-
Mitochondrial thiols in antioxidant protection and redox signaling: Distinct roles of glutathionylation and other thiol modifications
-
Murphy MP. Mitochondrial thiols in antioxidant protection and redox signaling: distinct roles of glutathionylation and other thiol modifications. Antioxid Redox Signal 16: 476-495, 2012.
-
(2012)
Antioxid Redox Signal
, vol.16
, pp. 476-495
-
-
Murphy, M.P.1
-
166
-
-
39149138715
-
Overexpression of glutaredoxin-2 reduces myocardial cell death by preventing both apoptosis and necrosis
-
Nagy N, Malik G, Tosaki A, Ho YS, Maulik N, and Das DK. Overexpression of glutaredoxin-2 reduces myocardial cell death by preventing both apoptosis and necrosis. J Mol Cell Cardiol 44: 252-260, 2008.
-
(2008)
J Mol Cell Cardiol
, vol.44
, pp. 252-260
-
-
Nagy, N.1
Malik, G.2
Tosaki, A.3
Ho, Y.S.4
Maulik, N.5
Das, D.K.6
-
167
-
-
79954528153
-
High doses of vitamin e improve mitochondrial dysfunction in rat hippocampus and frontal cortex upon aging
-
Navarro A, Bandez MJ, Lopez-Cepero JM, Gomez C, Boveris AD, Cadenas E, and Boveris A. High doses of vitamin E improve mitochondrial dysfunction in rat hippocampus and frontal cortex upon aging. Am J Physiol Regul Integr Comp Physiol 300: R827-R834, 2011.
-
(2011)
Am J Physiol Regul Integr Comp Physiol
, vol.300
-
-
Navarro, A.1
Bandez, M.J.2
Lopez-Cepero, J.M.3
Gomez, C.4
Boveris, A.D.5
Cadenas, E.6
Boveris, A.7
-
168
-
-
6344289360
-
Rat brain and liver mitochondria develop oxidative stress and lose enzymatic activities on aging
-
Navarro A and Boveris A. Rat brain and liver mitochondria develop oxidative stress and lose enzymatic activities on aging. Am J Physiol Regul Integr Comp Physiol 287: R1244-R1249, 2004.
-
(2004)
Am J Physiol Regul Integr Comp Physiol
, vol.287
-
-
Navarro, A.1
Boveris, A.2
-
169
-
-
34249829274
-
Brain mitochondrial dysfunction in aging: Conditions that improve survival, neurological performance and mitochondrial function
-
Navarro A and Boveris A. Brain mitochondrial dysfunction in aging: conditions that improve survival, neurological performance and mitochondrial function. Front Biosci 12: 1154-1163, 2007.
-
(2007)
Front Biosci
, vol.12
, pp. 1154-1163
-
-
Navarro, A.1
Boveris, A.2
-
170
-
-
33847059997
-
The mitochondrial energy transduction system and the aging process
-
Navarro A and Boveris A. The mitochondrial energy transduction system and the aging process. Am J Physiol Cell Physiol 292: C670-C686, 2007.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
-
-
Navarro, A.1
Boveris, A.2
-
171
-
-
51249095380
-
Mitochondrial nitric oxide synthase, mitochondrial brain dysfunction in aging, and mitochondria-targeted antioxidants
-
Navarro A and Boveris A. Mitochondrial nitric oxide synthase, mitochondrial brain dysfunction in aging, and mitochondria-targeted antioxidants. Adv Drug Deliv Rev 60: 1534-1544, 2008.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 1534-1544
-
-
Navarro, A.1
Boveris, A.2
-
172
-
-
67349122601
-
Human brain cortex: Mitochondrial oxidative damage and adaptive response in Parkinsons disease and in dementia with Lewy bodies
-
Navarro A, Boveris A, Bandez MJ, Sanchez-Pino MJ, Gomez C, Muntane G, and Ferrer I. Human brain cortex: mitochondrial oxidative damage and adaptive response in Parkinsons disease and in dementia with Lewy bodies. Free Radic Biol Med 46: 1574-1580, 2009.
-
(2009)
Free Radic Biol Med
, vol.46
, pp. 1574-1580
-
-
Navarro, A.1
Boveris, A.2
Bandez, M.J.3
Sanchez-Pino, M.J.4
Gomez, C.5
Muntane, G.6
Ferrer, I.7
-
173
-
-
38949115246
-
Hippocampal mitochondrial dysfunction in rat aging
-
Navarro A, Lopez-Cepero JM, Bandez MJ, Sanchez-Pino M-J, Gomez C, Cadenas
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.294
-
-
Navarro, A.1
Lopez-Cepero, J.M.2
Bandez, M.J.3
Sanchez-Pino, M.-J.4
Gomez, C.5
Cadenas, E.6
Boveris, A.7
-
174
-
-
0033826520
-
Role for mitochondrial oxidants as regulators of cellular metabolism
-
Nemoto S, Takeda K, Yu ZX, Ferrans VJ, and Finkel T. Role for mitochondrial oxidants as regulators of cellular metabolism. Mol Cell Biol 20: 7311-7318, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 7311-7318
-
-
Nemoto, S.1
Takeda, K.2
Yu, Z.X.3
Ferrans, V.J.4
Finkel, T.5
-
175
-
-
33746841367
-
Nitric oxide and mitochondrial biogenesis
-
Nisoli E and Carruba MO. Nitric oxide and mitochondrial biogenesis. J Cell Sci 119: 2855-2862, 2006.
-
(2006)
J Cell Sci
, vol.119
, pp. 2855-2862
-
-
Nisoli, E.1
Carruba, M.O.2
-
176
-
-
0037827160
-
Increased expression of mitochondrial peroxiredoxin-3 (thioredoxin peroxidase-2) protects cancer cells against hypoxia and drug-induced hydrogen peroxide-dependent apoptosis
-
Nonn L, Berggren M, and Powis G. Increased expression of mitochondrial peroxiredoxin-3 (thioredoxin peroxidase-2) protects cancer cells against hypoxia and drug-induced hydrogen peroxide-dependent apoptosis. Mol Cancer Res 1: 682-689, 2003.
-
(2003)
Mol Cancer Res
, vol.1
, pp. 682-689
-
-
Nonn, L.1
Berggren, M.2
Powis, G.3
-
177
-
-
0345146921
-
Reversible inactivation of alpha-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status
-
Nulton-Persson AC, Starke DW, Mieyal JJ, and Szweda LI. Reversible inactivation of alpha-ketoglutarate dehydrogenase in response to alterations in the mitochondrial glutathione status. Biochemistry 42: 4235-4242, 2003.
-
(2003)
Biochemistry
, vol.42
, pp. 4235-4242
-
-
Nulton-Persson, A.C.1
Starke, D.W.2
Mieyal, J.J.3
Szweda, L.I.4
-
178
-
-
79959338922
-
AMPK is a direct adenylate charge-regulated protein kinase
-
Oakhill JS, Steel R, Chen ZP, Scott JW, Ling N, Tam S, and Kemp BE. AMPK is a direct adenylate charge-regulated protein kinase. Science 332: 1433-1435, 2011.
-
(2011)
Science
, vol.332
, pp. 1433-1435
-
-
Oakhill, J.S.1
Steel, R.2
Chen, Z.P.3
Scott, J.W.4
Ling, N.5
Tam, S.6
Kemp, B.E.7
-
179
-
-
68949215885
-
Role of hydrogen peroxide in NF-kB activation: From inducer to modulator
-
Oliveira-Marques V, Marinho HS, Cyrne L, and Antunes F. Role of hydrogen peroxide in NF-kB activation: from inducer to modulator. Antioxid Redox Signal 11: 2223-2243, 2009.
-
(2009)
Antioxid Redox Signal
, vol.11
, pp. 2223-2243
-
-
Oliveira-Marques, V.1
Marinho, H.S.2
Cyrne, L.3
Antunes, F.4
-
180
-
-
0032493729
-
Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway
-
Pap M and Cooper GM. Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway. J Biol Chem 273: 19929-19932, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 19929-19932
-
-
Pap, M.1
Cooper, G.M.2
-
181
-
-
52449134835
-
Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA
-
Parone PA, Da Cruz S, Tondera D, Mattenberger Y, James DI, Maechler P, Barja F, and Martinou JC. Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA. PLoS One 3: e3257, 2008.
-
(2008)
PLoS One
, vol.3
-
-
Parone, P.A.1
Da Cruz, S.2
Tondera, D.3
Mattenberger, Y.4
James, D.I.5
Maechler, P.6
Barja, F.7
Martinou, J.C.8
-
182
-
-
3042602196
-
Mitochondrial thioredoxin system: Effects of TrxR2 overexpression on redox balance, cell growth, and apoptosis
-
Patenaude A, Ven Murthy MR, and Mirault ME. Mitochondrial thioredoxin system: effects of TrxR2 overexpression on redox balance, cell growth, and apoptosis. J Biol Chem 279: 27302-27314, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 27302-27314
-
-
Patenaude, A.1
Ven Murthy, M.R.2
Mirault, M.E.3
-
183
-
-
9144258564
-
Catalase and peroxiredoxin 5 protect Xenopus embryos against alcohol-induced ocular anomalies
-
Peng Y, Yang PH, Guo Y, Ng SS, Liu J, Fung PC, Tay D, Ge J, He ML, Kung HF, and Lin MC. Catalase and peroxiredoxin 5 protect Xenopus embryos against alcohol-induced ocular anomalies. Invest Ophthalmol Vis Sci 45: 23-29, 2004.
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, pp. 23-29
-
-
Peng, Y.1
Yang, P.H.2
Guo, Y.3
Ng, S.S.4
Liu, J.5
Fung, P.C.6
Tay, D.7
Ge, J.8
He, M.L.9
Kung, H.F.10
Lin, M.C.11
-
184
-
-
39149137166
-
Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress
-
Perez VI, Lew CM, Cortez LA, Webb CR, Rodriguez M, Liu Y, Qi W, Li Y, Chaudhuri A, Van Remmen H, Richardson A, and Ikeno Y. Thioredoxin 2 haploinsufficiency in mice results in impaired mitochondrial function and increased oxidative stress. Free Radic Biol Med 44: 882-892, 2008.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 882-892
-
-
Perez, V.I.1
Lew, C.M.2
Cortez, L.A.3
Webb, C.R.4
Rodriguez, M.5
Liu, Y.6
Qi, W.7
Li, Y.8
Chaudhuri, A.9
Van Remmen, H.10
Richardson, A.11
Ikeno, Y.12
-
185
-
-
0031824258
-
Effects of healthy aging on the regional cerebral metabolic rate of glucose assessed with statistical parametric mapping
-
Petit-Taboue MC, Landeau B, Desson JF, Desgranges B, and Baron JC. Effects of healthy aging on the regional cerebral metabolic rate of glucose assessed with statistical parametric mapping. Neuroimage 7: 176-184, 1998.
-
(1998)
Neuroimage
, vol.7
, pp. 176-184
-
-
Petit-Taboue, M.C.1
Landeau, B.2
Desson, J.F.3
Desgranges, B.4
Baron, J.C.5
-
186
-
-
0035344460
-
Versatility of the mitochondrial protein import machinery
-
Pfanner N and Geissler A. Versatility of the mitochondrial protein import machinery. Nat Rev Mol Cell Biol 2: 339-349, 2001.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 339-349
-
-
Pfanner, N.1
Geissler, A.2
-
187
-
-
20444461625
-
The charcot-marie-tooth type 2a gene product, mfn2, up-regulates fuel oxidation through expression of oxphos system
-
Pich S, Bach D, Briones P, Liesa M, Camps M, Testar X, Palacin M, and Zorzano A. The Charcot-Marie-Tooth type 2A gene product, Mfn2, up-regulates fuel oxidation through expression of OXPHOS system. Hum Mol Genet 14: 1405-1415, 2005.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 1405-1415
-
-
Pich, S.1
Bach, D.2
Briones, P.3
Liesa, M.4
Camps, M.5
Testar, X.6
Palacin, M.7
Zorzano, A.8
-
188
-
-
24144487005
-
Angiotensin II induces tyrosine nitration and activation of ERK1/2 in vascular smooth muscle cells
-
Pinzar E, Wang T, Garrido MR, Xu W, Levy P, and Bottari SP. Angiotensin II induces tyrosine nitration and activation of ERK1/2 in vascular smooth muscle cells. FEBS Lett 579: 5100-5104, 2005.
-
(2005)
FEBS Lett
, vol.579
, pp. 5100-5104
-
-
Pinzar, E.1
Wang, T.2
Garrido, M.R.3
Xu, W.4
Levy, P.5
Bottari, S.P.6
-
189
-
-
33745713089
-
Effect of oxidative stress on dynamics of mitochondrial reticulum
-
Pletjushkina OY, Lyamzaev KG, Popova EN, Nepryakhina OK, Ivanova OY, Domnina LV, Chernyak BV, and Skulachev VP. Effect of oxidative stress on dynamics of mitochondrial reticulum. Biochim Biophys Acta 1757: 518-524, 2006.
-
(2006)
Biochim Biophys Acta
, vol.1757
, pp. 518-524
-
-
Pletjushkina, O.Y.1
Lyamzaev, K.G.2
Popova, E.N.3
Nepryakhina, O.K.4
Ivanova, O.Y.5
Domnina, L.V.6
Chernyak, B.V.7
Skulachev, V.P.8
-
190
-
-
0029986691
-
Nitric oxide inhibits electron transfer and increases superoxide radical production in rat heart mitochondria and submitochondrial particles
-
Poderoso JJ, Carreras MC, Lisdero C, Riobo N, Schopfer F, and Boveris A. Nitric oxide inhibits electron transfer and increases superoxide radical production in rat heart mitochondria and submitochondrial particles. Arch Biochem Biophys 328: 85-92, 1996.
-
(1996)
Arch Biochem Biophys
, vol.328
, pp. 85-92
-
-
Poderoso, J.J.1
Carreras, M.C.2
Lisdero, C.3
Riobo, N.4
Schopfer, F.5
Boveris, A.6
-
191
-
-
0032960205
-
The reaction of nitric oxide with ubiquinol: Kinetic properties and biological significance
-
Poderoso JJ, Carreras MC, Scho pfer F, Lisdero C, Riobo N, Giulivi C, Boveris AD, Boveris A, and Cadenas E. The reaction of nitric oxide with ubiquinol: kinetic properties and biological significance. Free Radic Biol Med 26: 925-935, 1999.
-
(1999)
Free Radic Biol Med
, vol.26
, pp. 925-935
-
-
Poderoso, J.J.1
Carreras, M.C.2
Scho Pfer, F.3
Lisdero, C.4
Riobo, N.5
Giulivi, C.6
Boveris, A.D.7
Boveris, A.8
Cadenas, E.9
-
192
-
-
0033621429
-
The regulation of mitochondrial oxygen uptake by redox reactions involving nitric oxide and ubiquinol
-
Poderoso JJ, Lisdero C, Schopfer F, Riobo N, Carreras MC, Cadenas E, and Boveris A. The regulation of mitochondrial oxygen uptake by redox reactions involving nitric oxide and ubiquinol. J Biol Chem 274: 37709-37716, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 37709-37716
-
-
Poderoso, J.J.1
Lisdero, C.2
Schopfer, F.3
Riobo, N.4
Carreras, M.C.5
Cadenas, E.6
Boveris, A.7
-
193
-
-
77952776083
-
Glutathionylation of adenine nucleotide translocase induced by carbon monoxide prevents mitochondrial membrane permeabilization and apoptosis
-
Queiroga CS, Almeida AS, Martel C, Brenner C, Alves PM, and Vieira HL. Glutathionylation of adenine nucleotide translocase induced by carbon monoxide prevents mitochondrial membrane permeabilization and apoptosis. J Biol Chem 285: 17077-17088, 2010.
-
(2010)
J Biol Chem
, vol.285
, pp. 17077-17088
-
-
Queiroga, C.S.1
Almeida, A.S.2
Martel, C.3
Brenner, C.4
Alves, P.M.5
Vieira, H.L.6
-
194
-
-
80255127115
-
Dual localization of glutathione S-transferase in the cytosol and mitochondria: Implications in oxidative stress, toxicity, and disease
-
Raza H. Dual localization of glutathione S-transferase in the cytosol and mitochondria: implications in oxidative stress, toxicity, and disease. FEBS J 278: 4243-4521, 2011.
-
(2011)
FEBS J
, vol.278
, pp. 4243-4521
-
-
Raza, H.1
-
195
-
-
33845197506
-
Effects of age and caloric intake on glutathione redox state in different brain regions of C57BL/6 and DBA/2 mice
-
Rebrin I, Forster MJ, and Sohal RS. Effects of age and caloric intake on glutathione redox state in different brain regions of C57BL/6 and DBA/2 mice. Brain Res 1127: 10-18, 2007.
-
(2007)
Brain Res
, vol.1127
, pp. 10-18
-
-
Rebrin, I.1
Forster, M.J.2
Sohal, R.S.3
-
196
-
-
0041326831
-
Effects of age and caloric restriction on glutathione redox state in mice
-
Rebrin I, Kamzalov S, and Sohal RS. Effects of age and caloric restriction on glutathione redox state in mice. Free Radic Biol Med 35: 626-635, 2003.
-
(2003)
Free Radic Biol Med
, vol.35
, pp. 626-635
-
-
Rebrin, I.1
Kamzalov, S.2
Sohal, R.S.3
-
197
-
-
79951643450
-
Multiple functions of peroxiredoxins: Peroxidases, sensors and regulators of the intracellular messenger HO, and protein chaperones
-
Rhee SG and Woo HA. Multiple functions of peroxiredoxins: peroxidases, sensors and regulators of the intracellular messenger HO, and protein chaperones. Antioxid Redox Signal 15: 781-794, 2011.
-
(2011)
Antioxid Redox Signal
, vol.15
, pp. 781-794
-
-
Rhee, S.G.1
Woo, H.A.2
-
198
-
-
79960543076
-
H (2)O(2): A dynamic neuromodulator
-
Rice ME. H(2)O(2): a dynamic neuromodulator. Neuroscientist 17: 389-406, 2011.
-
(2011)
Neuroscientist
, vol.17
, pp. 389-406
-
-
Rice, M.E.1
-
199
-
-
78650869592
-
Mitochondrial ROS generation and its regulation: Mechanisms involved in H(2)O(2) signaling
-
Rigoulet M, Yoboue ED, and Devin A. Mitochondrial ROS generation and its regulation: mechanisms involved in H(2)O(2) signaling. Antioxid Redox Signal 14: 459-468, 2011.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 459-468
-
-
Rigoulet, M.1
Yoboue, E.D.2
Devin, A.3
-
200
-
-
0037044724
-
The modulation of mitochondrial nitric oxide synthase activity in rat brain development
-
Riobo N, Melani M, Sanjuan N, Fiszman ML, Gravielle MC, Carreras MC, Cadenas E, and Poderoso JJ. The modulation of mitochondrial nitric oxide synthase activity in rat brain development. J Biol Chem 277: 42447-42455, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 42447-42455
-
-
Riobo, N.1
Melani, M.2
Sanjuan, N.3
Fiszman, M.L.4
Gravielle, M.C.5
Carreras, M.C.6
Cadenas, E.7
Poderoso, J.J.8
-
201
-
-
33749317431
-
The thioredoxin system in aging muscle key role of mitochondrial thioredoxin reductase in the protective effects of caloric restriction?
-
Rohrbach S, Gruenler S, Teschner M, and Holtz J. The thioredoxin system in aging muscle: key role of mitochondrial thioredoxin reductase in the protective effects of caloric restriction? Am J Physiol Regul Integr Comp Physiol 291: R927-R935, 2006.
-
(2006)
Am J Physiol Regul Integr Comp Physiol
, vol.291
-
-
Rohrbach, S.1
Gruenler, S.2
Teschner, M.3
Holtz, J.4
-
202
-
-
33745635338
-
Mitochondrial NADPH transhydrogenase, and disease
-
Rydstrom J. Mitochondrial NADPH, transhydrogenase, and disease. Biochim Biophys Acta 1757: 721-726, 2006.
-
(2006)
Biochim Biophys Acta
, vol.1757
, pp. 721-726
-
-
Rydstrom, J.1
-
203
-
-
49349105791
-
Knockdown of cytosolic glutaredoxin 1 leads to loss of mitochondrial membrane potential: Implication in neurodegenerative diseases
-
Saeed U, Durgadoss L, Valli RK, Joshi DC, Joshi PG, and Ravindranath V. Knockdown of cytosolic glutaredoxin 1 leads to loss of mitochondrial membrane potential: implication in neurodegenerative diseases. PLoS One 3: e2459, 2008.
-
(2008)
PLoS One
, vol.3
-
-
Saeed, U.1
Durgadoss, L.2
Valli, R.K.3
Joshi, D.C.4
Joshi, P.G.5
Ravindranath, V.6
-
204
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K, and Ichijo H. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J 17: 2596-2606, 1998.
-
(1998)
EMBO J
, vol.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
Takeda, K.4
Tobiume, K.5
Sawada, Y.6
Kawabata, M.7
Miyazono, K.8
Ichijo, H.9
-
205
-
-
0031984178
-
A Ginkgo biloba extract (EGb 761) prevents mitochondrial aging by protecting against oxidative stress
-
Sastre J, Millan A, Garcia de la Asuncion J, Pla R, Juan G, Pallardo, OConnor E, Martin JA, Droy-Lefaix MT, and Vina J. A Ginkgo biloba extract (EGb 761) prevents mitochondrial aging by protecting against oxidative stress. Free Radic Biol Med 24: 298-304, 1998.
-
(1998)
Free Radic Biol Med
, vol.24
, pp. 298-304
-
-
Sastre, J.1
Millan, A.2
De La Garcia, A.J.3
Pla, R.4
Juan, G.5
Pallardo Oconnor, E.6
Martin, J.A.7
Droy-Lefaix, M.T.8
Vina, J.9
-
206
-
-
42049114034
-
Transcriptional paradigms in mammalian mitochondrial biogenesis and function
-
Scarpulla RC. Transcriptional paradigms in mammalian mitochondrial biogenesis and function. Physiol Rev 88: 611-638, 2008.
-
(2008)
Physiol Rev
, vol.88
, pp. 611-638
-
-
Scarpulla, R.C.1
-
207
-
-
0035371184
-
Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple
-
Schafer FQ and Buettner GR. Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple. Free Radic Biol Med 30: 1191-1212, 2001.
-
(2001)
Free Radic Biol Med
, vol.30
, pp. 1191-1212
-
-
Schafer, F.Q.1
Buettner, G.R.2
-
208
-
-
0038230469
-
Supercomplexes in the respiratory chains of yeast and mammalian mitochondria
-
Schagger H and Pfeiffer K. Supercomplexes in the respiratory chains of yeast and mammalian mitochondria. EMBO J 19: 1777-1783, 2000.
-
(2000)
EMBO J
, vol.19
, pp. 1777-1783
-
-
Schagger, H.1
Pfeiffer, K.2
-
209
-
-
33750624967
-
Mitochondrial signaling TOR and life span
-
Schieke SM and Finkel T. Mitochondrial signaling, TOR, and life span. Biol Chem 387: 1357-1361, 2006.
-
(2006)
Biol Chem
, vol.387
, pp. 1357-1361
-
-
Schieke, S.M.1
Finkel, T.2
-
210
-
-
0025744144
-
Phospholipid hydroperoxide glutathione peroxidase is a selenoenzyme distinct from the classical glutathione peroxidase as evident from cDNA and amino acid sequencing
-
Schuckelt R, Brigelius-Flohe R, Maiorino M, Roveri A, Reumkens J, Strassburger W, Ursini F, Wolf B, and Flohe L. Phospholipid hydroperoxide glutathione peroxidase is a selenoenzyme distinct from the classical glutathione peroxidase as evident from cDNA and amino acid sequencing. Free Radic Res Commun 14: 343-361, 1991.
-
(1991)
Free Radic Res Commun
, vol.14
, pp. 343-361
-
-
Schuckelt, R.1
Brigelius-Flohe, R.2
Maiorino, M.3
Roveri, A.4
Reumkens, J.5
Strassburger, W.6
Ursini, F.7
Wolf, B.8
Flohe, L.9
-
211
-
-
66349120000
-
From protons to OXPHOS supercomplexes and Alzheimers disease: Structuredynamics-function relationships of energy-transducing membranes
-
Seelert H, Dani DN, Dante S, Hauss T, Krause F, Schafer E, Frenzel M, Poetsch A, Rexroth S, Schwassmann HJ, Suhai T, Vonck J, and Dencher NA. From protons to OXPHOS supercomplexes and Alzheimers disease: structuredynamics- function relationships of energy-transducing membranes. Biochim Biophys Acta 1787: 657-671, 2009.
-
(2009)
Biochim Biophys Acta
, vol.1787
, pp. 657-671
-
-
Seelert, H.1
Dani, D.N.2
Dante, S.3
Hauss, T.4
Krause, F.5
Schafer, E.6
Frenzel, M.7
Poetsch, A.8
Rexroth, S.9
Schwassmann, H.J.10
Suhai, T.11
Vonck, J.12
Dencher, N.A.13
-
212
-
-
3142594193
-
The LKB1 tumor suppressor negatively regulates mTOR signaling
-
Shaw RJ, Bardeesy N, Manning BD, Lopez L, Kosmatka M, DePinho RA, and Cantley LC. The LKB1 tumor suppressor negatively regulates mTOR signaling. Cancer Cell 6: 91-99, 2004.
-
(2004)
Cancer Cell
, vol.6
, pp. 91-99
-
-
Shaw, R.J.1
Bardeesy, N.2
Manning, B.D.3
Lopez, L.4
Kosmatka, M.5
Depinho, R.A.6
Cantley, L.C.7
-
213
-
-
77953810393
-
Diminished NADPH transhydrogenase activity and mitochondrial redox regulation in human failing myocardium
-
Sheeran FL, Rydstrom J, Shakhparonov MI, Pestov NB, and Pepe S. Diminished NADPH transhydrogenase activity and mitochondrial redox regulation in human failing myocardium. Biochim Biophys Acta 1797: 1138-1148, 2010.
-
(2010)
Biochim Biophys Acta
, vol.1797
, pp. 1138-1148
-
-
Sheeran, F.L.1
Rydstrom, J.2
Shakhparonov, M.I.3
Pestov, N.B.4
Pepe, S.5
-
215
-
-
0028116159
-
Effect of age and caloric restriction on DNA oxidative damage in different tissues of C57BL/6 mice
-
Sohal RS, Agarwal S, Candas M, Forster M, and Lal H. Effect of age and caloric restriction on DNA oxidative damage in different tissues of C57BL/6 mice. Mech Ageing Dev 76: 215-224, 1994.
-
(1994)
Mech Ageing Dev
, vol.76
, pp. 215-224
-
-
Sohal, R.S.1
Agarwal, S.2
Candas, M.3
Forster, M.4
Lal, H.5
-
216
-
-
68149103297
-
Mitofusins and OPA1 mediate sequential steps in mitochondrial membrane fusion
-
Song Z, Ghochani M, McCaffery JM, Frey TG, and Chan DC. Mitofusins and OPA1 mediate sequential steps in mitochondrial membrane fusion. Mol Biol Cell 20: 3525-3532, 2009.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 3525-3532
-
-
Song, Z.1
Ghochani, M.2
McCaffery, J.M.3
Frey, T.G.4
Chan, D.C.5
-
217
-
-
33749999530
-
Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
-
St-Pierre J, Drori S, Uldry M, Silvaggi JM, Rhee J, Jager S, Handschin C, Zheng K, Lin J, Yang W, Simon DK, Bachoo R, and Spiegelman BM. Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 127: 397-408, 2006.
-
(2006)
Cell
, vol.127
, pp. 397-408
-
-
St-Pierre, J.1
Drori, S.2
Uldry, M.3
Silvaggi, J.M.4
Rhee, J.5
Jager, S.6
Handschin, C.7
Zheng, K.8
Lin, J.9
Yang, W.10
Simon, D.K.11
Bachoo, R.12
Spiegelman, B.M.13
-
218
-
-
67650914230
-
AMPK in health and disease
-
Steinberg GR and Kemp BE. AMPK in Health and Disease. Physiol Rev 89: 1025-1078, 2009.
-
(2009)
Physiol Rev
, vol.89
, pp. 1025-1078
-
-
Steinberg, G.R.1
Kemp, B.E.2
-
219
-
-
36348947406
-
Mitochondrial respiratory chain is involved in insulin-stimulated hydrogen peroxide production and plays an integral role in insulin receptor autophosphorylation in neurons
-
Storozhevykh TP, Senilova YE, Persiyantseva NA, Pinelis VG, and Pomytkin IA. Mitochondrial respiratory chain is involved in insulin-stimulated hydrogen peroxide production and plays an integral role in insulin receptor autophosphorylation in neurons. BMC Neurosci 8: 84, 2007.
-
(2007)
BMC Neurosci
, vol.8
, pp. 84
-
-
Storozhevykh, T.P.1
Senilova, Y.E.2
Persiyantseva, N.A.3
Pinelis, V.G.4
Pomytkin, I.A.5
-
220
-
-
1542723493
-
Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione syn thesis which is reversible with lipoic acid
-
Suh JH, Shenvi SV, Dixon BM, Liu H, Jaiswal AK, Liu RM, and Hagen TM. Decline in transcriptional activity of Nrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid. Proc Natl Acad Sci U S A 101: 3381-3386, 2004.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3381-3386
-
-
Suh, J.H.1
Shenvi, S.V.2
Dixon, B.M.3
Liu, H.4
Jaiswal, A.K.5
Liu, R.M.6
Hagen, T.M.7
-
221
-
-
0034846004
-
Age-specific changes in expression, activity, and activation of the c-Jun NH(2)-terminal kinase and p38 mitogen-Activated protein kinases by methyl methanesulfonate in rats
-
Suh Y. Age-specific changes in expression, activity, and activation of the c-Jun NH(2)-terminal kinase and p38 mitogen-Activated protein kinases by methyl methanesulfonate in rats. Mech Ageing Dev 122: 1797-1811, 2001.
-
(2001)
Mech Ageing Dev
, vol.122
, pp. 1797-1811
-
-
Suh, Y.1
-
222
-
-
34648819814
-
Treating neurodegeneration by modifying mitochondria: Potential solutions to a Complex problem
-
Swerdlow RH. Treating neurodegeneration by modifying mitochondria: potential solutions to a Complex problem. Antioxid Redox Signal 10, 1591-1603, 2007.
-
(2007)
Antioxid Redox Signal
, vol.10
, pp. 1591-1603
-
-
Swerdlow, R.H.1
-
223
-
-
80053892506
-
Brain aging Alzheimers disease, and mitochondria
-
Swerdlow RH. Brain aging, Alzheimers disease, and mitochondria. Biochim Biophys Acta 1812: 1630-1639, 2011.
-
(2011)
Biochim Biophys Acta
, vol.1812
, pp. 1630-1639
-
-
Swerdlow, R.H.1
-
224
-
-
42049090126
-
Mitochondria: The hub of cellular Ca2 + signaling
-
Szabadkai G and Duchen MR. Mitochondria: the hub of cellular Ca2 + signaling. Physiology (Bethesda) 23: 84-94, 2008.
-
(2008)
Physiology (Bethesda)
, vol.23
, pp. 84-94
-
-
Szabadkai, G.1
Duchen, M.R.2
-
225
-
-
84887212354
-
Heterozygous mutation of Opa1 in Drosophila shortens lifespan mediated through increased reactive oxygen species production
-
Tang S, Le PK, Tse S, Wallace DC, and Huang T. Heterozygous mutation of Opa1 in Drosophila shortens lifespan mediated through increased reactive oxygen species production. PLoS One 4: e4492, 2009.
-
(2009)
PLoS One
, vol.4
-
-
Tang, S.1
Le Tse, P.K.S.2
Wallace, D.C.3
Huang, T.4
-
226
-
-
0037490142
-
Reversible glutathionylation of complex i increases mitochondrial superoxide formation
-
Taylor ER, Hurrell F, Shannon RJ, Lin TK, Hirst J, and Murphy MP. Reversible glutathionylation of complex I increases mitochondrial superoxide formation. J Biol Chem 278: 19603-19610, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 19603-19610
-
-
Taylor, E.R.1
Hurrell, F.2
Shannon, R.J.3
Lin, T.K.4
Hirst, J.5
Murphy, M.P.6
-
227
-
-
0029015864
-
Protein sulfhydryls and their role in the antioxidant function of protein S-thiolation
-
Thomas JA, Poland B, and Honzatko R. Protein sulfhydryls and their role in the antioxidant function of protein S-thiolation. Arch Biochem Biophys 319: 1-9, 1995.
-
(1995)
Arch Biochem Biophys
, vol.319
, pp. 1-9
-
-
Thomas, J.A.1
Poland, B.2
Honzatko, R.3
-
228
-
-
0142150051
-
Mitochondrial formation of reactive oxygen species
-
Turrens JF. Mitochondrial formation of reactive oxygen species. J Physiol 552: 335-344, 2003.
-
(2003)
J Physiol
, vol.552
, pp. 335-344
-
-
Turrens, J.F.1
-
229
-
-
0019083215
-
Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria
-
Turrens JF and Boveris A. Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria. Biochem J 191: 421-427, 1980.
-
(1980)
Biochem J
, vol.191
, pp. 421-427
-
-
Turrens, J.F.1
Boveris, A.2
-
230
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
Twig G, Elorza A, Molina AJ, Mohamed H, Wikstrom JD, Walzer G, Stiles L, Haigh SE, Katz S, Las G, Alroy J, Wu M, Py BF, Yuan J, Deeney JT, Corkey BE, and Shirihai OS. Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. embo J 27: 433-446, 2008.
-
(2008)
Embo J
, vol.27
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
Molina, A.J.3
Mohamed, H.4
Wikstrom, J.D.5
Walzer, G.6
Stiles, L.7
Haigh, S.E.8
Katz, S.9
Las, G.10
Alroy, J.11
Wu, M.12
Py, B.F.13
Yuan, J.14
Deeney, J.T.15
Corkey, B.E.16
Shirihai, O.S.17
-
231
-
-
79954571354
-
The interplay between mitochondrial dynamics and mitophagy
-
Twig G and Shirihai OS. The interplay between mitochondrial dynamics and mitophagy. Antioxid Redox Signal 14: 1939-1951, 2011.
-
(2011)
Antioxid Redox Signal
, vol.14
, pp. 1939-1951
-
-
Twig, G.1
Shirihai, O.S.2
-
232
-
-
0031225515
-
Phospholipid hydroperoxide glutathione peroxidase (PHGPx) more than an antioxidant enzyme?
-
Ursini F, Maiorino M, and Roveri A. Phospholipid hydroperoxide glutathione peroxidase (PHGPx): more than an antioxidant enzyme? Biomed Environ Sci 1997: 327-332, 1997.
-
(1997)
Biomed Environ Sci
, pp. 327-332
-
-
Ursini, F.1
Maiorino, M.2
Roveri, A.3
-
233
-
-
34249819641
-
Mitochondrial nitric oxide synthase, a voltage-dependent enzyme, is responsible for nitric oxide diffusion to cytosol
-
Valdez LB and Boveris A. Mitochondrial nitric oxide synthase, a voltage-dependent enzyme, is responsible for nitric oxide diffusion to cytosol. Front Biosci 12: 1210-1219, 2007.
-
(2007)
Front Biosci
, vol.12
, pp. 1210-1219
-
-
Valdez, L.B.1
Boveris, A.2
-
234
-
-
33748295795
-
Insulin signaling in the central nervous system: Learning to survive
-
van der Heide LP, Ramakers GM, and Smidt MP. Insulin signaling in the central nervous system: learning to survive. Prog Neurobiol 79: 205-221, 2006.
-
(2006)
Prog Neurobiol
, vol.79
, pp. 205-221
-
-
Van Der Heide, L.P.1
Ramakers, G.M.2
Smidt, M.P.3
-
235
-
-
64949111531
-
Current thoughts on the role of mitochondria and free radicals in the biology of aging
-
Van Remmen H and Jones DP. Current thoughts on the role of mitochondria and free radicals in the biology of aging. J Gerontol A Biol Sci Med Sci 64: 171-174, 2009.
-
(2009)
J Gerontol A Biol Sci Med Sci
, vol.64
, pp. 171-174
-
-
Van Remmen, H.1
Jones, D.P.2
-
236
-
-
67749147469
-
Absence of nitric-oxide synthase in sequentially purified rat liver mitochondria
-
Venkatakrishnan P, Nakayasu ES, Almeida IC, and Miller RT. Absence of nitric-oxide synthase in sequentially purified rat liver mitochondria. J Biol Chem 284: 19843-19855, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 19843-19855
-
-
Venkatakrishnan, P.1
Nakayasu, E.S.2
Almeida, I.C.3
Miller, R.T.4
-
237
-
-
84860296724
-
AMP-Activated protein kinase, stress responses and cardiovascular diseases
-
Wang S, Song P, and Zou MH. AMP-Activated protein kinase, stress responses and cardiovascular diseases. Clin Sci (Lond) 122: 555-573, 2012.
-
(2012)
Clin Sci (Lond)
, vol.122
, pp. 555-573
-
-
Wang, S.1
Song, P.2
Zou, M.H.3
-
238
-
-
67650732998
-
Impaired balance of mitochondrial fission and fusion in Alzheimers disease
-
Wang X, Su B, Lee HG, Li X, Perry G, Smith MA, and Zhu X. Impaired balance of mitochondrial fission and fusion in Alzheimers disease. J Neurosci 29: 9090-9103, 2009.
-
(2009)
J Neurosci
, vol.29
, pp. 9090-9103
-
-
Wang, X.1
Su, B.2
Lee, H.G.3
Li, X.4
Perry, G.5
Smith, M.A.6
Zhu, X.7
-
239
-
-
50049118173
-
Activation of the PPAR/PGC-1alpha pathway prevents a bioen-ergetic deficit and effectively improves a mitochondrial myopathy phenotype
-
Wenz T, Diaz F, Spiegelman BM, and Moraes CT. Activation of the PPAR/PGC-1alpha pathway prevents a bioen-ergetic deficit and effectively improves a mitochondrial myopathy phenotype. Cell Metab 8: 249-256, 2008.
-
(2008)
Cell Metab
, vol.8
, pp. 249-256
-
-
Wenz, T.1
Diaz, F.2
Spiegelman, B.M.3
Moraes, C.T.4
-
240
-
-
33845600791
-
Protein glutathiolation by nitric oxide: An intracellular mechanism regulating redox protein modification
-
West MB, Hill BG, Xuan YT, and Bhatnagar A. Protein glutathiolation by nitric oxide: an intracellular mechanism regulating redox protein modification. FASEB J 20: 1715-1717, 2006.
-
(2006)
FASEB J
, vol.20
, pp. 1715-1717
-
-
West, M.B.1
Hill, B.G.2
Xuan, Y.T.3
Bhatnagar, A.4
-
241
-
-
33750437278
-
Thermoregulatory and metabolic defects in Huntingtons disease transgenic mice implicate PGC-1alpha in Huntingtons disease neurodegeneration
-
Weydt P, Pineda VV, Torrence AE, Libby RT, Satterfield TF, Lazarowski ER, Gilbert ML, Morton GJ, Bammler TK, Strand AD, Cui L, Beyer RP, Easley CN, Smith AC, Krainc D, Luquet S, Sweet IR, Schwartz MW, and La Spada AR. Thermoregulatory and metabolic defects in Huntingtons disease transgenic mice implicate PGC-1alpha in Huntingtons disease neurodegeneration. Cell Metab 4: 349-362, 2006.
-
(2006)
Cell Metab
, vol.4
, pp. 349-362
-
-
Weydt, P.1
Pineda, V.V.2
Torrence, A.E.3
Libby, R.T.4
Satterfield, T.F.5
Lazarowski, E.R.6
Gilbert, M.L.7
Morton, G.J.8
Bammler, T.K.9
Strand, A.D.10
Cui, L.11
Beyer, R.P.12
Easley, C.N.13
Smith, A.C.14
Krainc, D.15
Luquet, S.16
Sweet, I.R.17
Schwartz, M.W.18
La Spada, A.R.19
-
242
-
-
0037444470
-
Mitogen-Activated protein kinase (MAPK) pathway activation: Effects of age and acute exercise on human skeletal muscle
-
Williamson D, Gallagher P, Harber M, Hollon C, and Trappe S. Mitogen-Activated protein kinase (MAPK) pathway activation: effects of age and acute exercise on human skeletal muscle. J Physiol 547: 977-987, 2003.
-
(2003)
J Physiol
, vol.547
, pp. 977-987
-
-
Williamson, D.1
Gallagher, P.2
Harber, M.3
Hollon, C.4
Trappe, S.5
-
243
-
-
0037076433
-
The c-Myc target gene PRDX3 is required for mitochondrial homeostasis and neoplastic transformation
-
Wonsey DR, Zeller KI, and Dang CV. The c-Myc target gene PRDX3 is required for mitochondrial homeostasis and neoplastic transformation. Proc Natl Acad Sci U S A 99: 6649-6654, 2002.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 6649-6654
-
-
Wonsey, D.R.1
Zeller, K.I.2
Dang, C.V.3
-
244
-
-
33745727818
-
Impairment of mitochondrial anti-oxidant defence in SOD1-related motor neuron injury and amelioration by ebselen
-
Wood-Allum CA, Barber SC, Kirby J, Heath P, Holden H, Mead R, Higginbottom A, Allen S, Beaujeux T, Alexson SE, Ince PG, and Shaw PJ. Impairment of mitochondrial anti-oxidant defence in SOD1-related motor neuron injury and amelioration by ebselen. Brain 129: 1693-1709, 2006.
-
(2006)
Brain
, vol.129
, pp. 1693-1709
-
-
Wood-Allum, C.A.1
Barber, S.C.2
Kirby, J.3
Heath, P.4
Holden, H.5
Mead, R.6
Higginbottom, A.7
Allen, S.8
Beaujeux, T.9
Alexson, S.E.10
Ince, P.G.11
Shaw, P.J.12
-
245
-
-
33749247065
-
Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells
-
Wu Z, Huang X, Feng Y, Handschin C, Gullicksen PS, Bare O, Labow M, Spiegelman B, and Stevenson SC. Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells. Proc Natl Acad Sci U S A 103: 14379-14384, 2006.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 14379-14384
-
-
Wu, Z.1
Huang, X.2
Feng, Y.3
Handschin, C.4
Gullicksen, P.S.5
Bare, O.6
Labow, M.7
Spiegelman, B.8
Stevenson, S.C.9
-
246
-
-
79954517977
-
Structure of mammalian AMPK and its regulation by ADP
-
Xiao B, Sanders MJ, Underwood E, Heath R, Mayer FV, Carmena D, Jing C, Walker PA, Eccleston JF, Haire LF, Saiu P, Howell SA, Aasland R, Martin SR, Carling D, and Gamblin SJ. Structure of mammalian AMPK and its regulation by ADP. Nature 472: 230-233, 2011.
-
(2011)
Nature
, vol.472
, pp. 230-233
-
-
Xiao, B.1
Sanders, M.J.2
Underwood, E.3
Heath, R.4
Mayer, F.V.5
Carmena, D.6
Jing, C.7
Walker, P.A.8
Eccleston, J.F.9
Haire, L.F.10
Saiu, P.11
Howell, S.A.12
Aasland, R.13
Martin, S.R.14
Carling, D.15
Gamblin, S.J.16
-
248
-
-
77956179987
-
Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence
-
Yao J, Hamilton RT, Cadenas E, and Brinton RD. Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence. Biochim Biophys Acta 1800: 1121-1126, 2010.
-
(2010)
Biochim Biophys Acta
, pp. 1121-1126
-
-
Yao, J.1
Hamilton, R.T.2
Cadenas, E.3
Brinton, R.D.4
-
249
-
-
70149093436
-
Mitochondrial bioenergetic deficit precedes Alzheimers pathology in female mouse model of Alzheimers disease
-
Yao J, Irwin RW, Zhao L, Nilsen J, Hamilton RT, and Brinton RD. Mitochondrial bioenergetic deficit precedes Alzheimers pathology in female mouse model of Alzheimers disease. Proc Natl Acad Sci U S A 106: 14670-14675, 2009.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 14670-14675
-
-
Yao, J.1
Irwin, R.W.2
Zhao, L.3
Nilsen, J.4
Hamilton, R.T.5
Brinton, R.D.6
-
250
-
-
71549131281
-
The energyredox axis in aging and age-related neurodegeneration
-
Yap LP, Garcia JV, Han D, and Cadenas E. The energyredox axis in aging and age-related neurodegeneration. Adv Drug Deliv Rev 61: 1283-1298, 2009.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 1283-1298
-
-
Yap, L.P.1
Garcia, J.V.2
Han, D.3
Cadenas, E.4
-
251
-
-
28244454785
-
Aconitase is the main functional target of aging in the citric acid cycle of kidney mitochondria from mice
-
Yarian CS, Toroser D, and Sohal RS. Aconitase is the main functional target of aging in the citric acid cycle of kidney mitochondria from mice. Mech Ageing Dev 127: 79-84, 2006.
-
(2006)
Mech Ageing Dev
, vol.127
, pp. 79-84
-
-
Yarian, C.S.1
Toroser, D.2
Sohal, R.S.3
-
252
-
-
84867725042
-
Mitochondrial thiols in the regulation of cell death pathways
-
Yin F, Sancheti H, and Cadenas E. Mitochondrial thiols in the regulation of cell death pathways. Antioxid Redox Signal 17: 1714-1727, 2012.
-
(2012)
Antioxid Redox Signal
, vol.17
, pp. 1714-1727
-
-
Yin, F.1
Sancheti, H.2
Cadenas, E.3
-
253
-
-
84855815901
-
Silencing of nicotinamide nucleotide transhydrogenase impairs cellular redox homeostasis and energy metabolism in PC12 cells
-
Yin F, Sancheti H, and Cadenas E. Silencing of nicotinamide nucleotide transhydrogenase impairs cellular redox homeostasis and energy metabolism in PC12 cells. Biochim Biophys Acta 1817: 401-409, 2012.
-
(2012)
Biochim Biophys Acta
, vol.1817
, pp. 401-409
-
-
Yin, F.1
Sancheti, H.2
Cadenas, E.3
-
254
-
-
33744480316
-
NAD+ and NADH in cellular functions and cell death
-
Ying W. NAD+ and NADH in cellular functions and cell death. Front Biosci 11: 3129-3148, 2006.
-
(2006)
Front Biosci
, vol.11
, pp. 3129-3148
-
-
Ying, W.1
-
255
-
-
37549068090
-
NAD+/NADH and NADP+/NADPH in cellular functions and cell death: Regulation and biological consequences
-
Ying W. NAD+/NADH and NADP+/NADPH in cellular functions and cell death: regulation and biological consequences. Antioxid Redox Signal 10: 179-206, 2008.
-
(2008)
Antioxid Redox Signal
, vol.10
, pp. 179-206
-
-
Ying, W.1
-
256
-
-
0043092647
-
The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1
-
Yoon Y, Krueger EW, Oswald BJ, and McNiven MA. The mitochondrial protein hFis1 regulates mitochondrial fission in mammalian cells through an interaction with the dynamin-like protein DLP1. Mol Cell Biol 23: 5409-5420, 2003.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5409-5420
-
-
Yoon, Y.1
Krueger, E.W.2
Oswald, B.J.3
McNiven, M.A.4
-
257
-
-
34548048824
-
Mitochondrial thioredoxin-2/peroxiredoxin-3 system functions in parallel with mitochondrial GSH system in protection against oxidative stress
-
Zhang H, Go YM, and Jones DP. Mitochondrial thioredoxin-2/peroxiredoxin-3 system functions in parallel with mitochondrial GSH system in protection against oxidative stress. Arch Biochem Biophys 465: 119-126, 2007.
-
(2007)
Arch Biochem Biophys
, vol.465
, pp. 119-126
-
-
Zhang, H.1
Go, Y.M.2
Jones, D.P.3
-
258
-
-
79959910616
-
The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells
-
Zhang Z, Wakabayashi N, Wakabayashi J, Tamura Y, Song WJ, Sereda S, Clerc P, Polster BM, Aja SM, Pletnikov MV, Kensler TW, Shirihai OS, Iijima M, Hussain MA, and Sesaki H. The dynamin-related GTPase Opa1 is required for glucose-stimulated ATP production in pancreatic beta cells. Mol Biol Cell 22: 2235-2245, 2011.
-
(2011)
Mol Biol Cell
, vol.22
, pp. 2235-2245
-
-
Zhang, Z.1
Wakabayashi, N.2
Wakabayashi, J.3
Tamura, Y.4
Song, W.J.5
Sereda, S.6
Clerc, P.7
Polster, B.M.8
Aja, S.M.9
Pletnikov, M.V.10
Kensler, T.W.11
Shirihai, O.S.12
Iijima, M.13
Hussain, M.A.14
Sesaki, H.15
-
259
-
-
0033427196
-
Age-Associated impairment in brain MAPK signal pathways and the effect of caloric restriction in Fischer 344 rats
-
Zhen X, Uryu K, Cai G, Johnson GP, and Friedman E. Age-Associated impairment in brain MAPK signal pathways and the effect of caloric restriction in Fischer 344 rats. J Gerontol A Biol Sci Med Sci 54: B539-B548, 1999.
-
(1999)
J Gerontol A Biol Sci Med Sci
, vol.54
-
-
Zhen, X.1
Uryu, K.2
Cai, G.3
Johnson, G.P.4
Friedman, E.5
-
260
-
-
0034863102
-
Regulation of muscle GLUT-4 transcription by AMP-Activated protein kinase
-
Zheng D, MacLean PS, Pohnert SC, Knight JB, Olson AL, Winder WW, and Dohm GL. Regulation of muscle GLUT-4 transcription by AMP-Activated protein kinase. J Appl Physiol 91: 1073-1083, 2001.
-
(2001)
J Appl Physiol
, vol.91
, pp. 1073-1083
-
-
Zheng, D.1
Maclean, P.S.2
Pohnert, S.C.3
Knight, J.B.4
Olson, A.L.5
Winder, W.W.6
Dohm, G.L.7
-
261
-
-
0032513362
-
Activation of the OxyR transcription factor by reversible disulfide bond formation
-
Zheng M, Aslund F, and Storz G. Activation of the OxyR transcription factor by reversible disulfide bond formation. Science 279: 1718-1721, 1998.
-
(1998)
Science
, vol.279
, pp. 1718-1721
-
-
Zheng, M.1
Aslund, F.2
Storz, G.3
-
262
-
-
43949146899
-
Hepatic mitochondrial transport of glutathione: Studies in isolated rat liver mitochondria and H4IIE rat hepatoma cells
-
Zhong Q, Putt DA, Xu F, and Lash LH. Hepatic mitochondrial transport of glutathione: studies in isolated rat liver mitochondria and H4IIE rat hepatoma cells. Arch Biochem Biophys 474: 119-127, 2008.
-
(2008)
Arch Biochem Biophys
, vol.474
, pp. 119-127
-
-
Zhong, Q.1
Putt, D.A.2
Xu, F.3
Lash, L.H.4
-
263
-
-
37349081929
-
C-Jun Nterminal kinase regulates mitochondrial bioenergetics by modulating pyruvate dehydrogenase activity in primary cortical neurons
-
Zhou Q, Lam PY, Han D, and Cadenas E. c-Jun Nterminal kinase regulates mitochondrial bioenergetics by modulating pyruvate dehydrogenase activity in primary cortical neurons. J Neurochem 104: 325-335, 2008.
-
(2008)
J Neurochem
, vol.104
, pp. 325-335
-
-
Zhou, Q.1
Lam, P.Y.2
Han, D.3
Cadenas, E.4
-
264
-
-
62849111251
-
Activation of c-Jun-N-terminal kinase and decline of mitochondrial pyruvate dehydrogenase activity during brain aging
-
Zhou Q, Lam PY, Han D, and Cadenas E. Activation of c-Jun-N-terminal kinase and decline of mitochondrial pyruvate dehydrogenase activity during brain aging. FEBS Lett 583: 1132-1140, 2009.
-
(2009)
FEBS Lett
, vol.583
, pp. 1132-1140
-
-
Zhou, Q.1
Lam, P.Y.2
Han, D.3
Cadenas, E.4
-
265
-
-
53049108896
-
Detoxification reactions: Relevance to aging
-
Zimniak P. Detoxification reactions: relevance to aging. Ageing Res Rev 7: 281-300, 2008.
-
(2008)
Ageing Res Rev
, vol.7
, pp. 281-300
-
-
Zimniak, P.1
|