Physical exercise prior and during treatment reduces sub-chronic doxorubicin-induced mitochondrial toxicity and oxidative stress

Mitochondrion

Volumn 20, Issue , 2015, Pages 22-33

  Marques Aleixo, Inês ^a   Santos Alves, Estela ^a,b   Mariani, Diogo ^a   Rizo Roca, David ^c   Padrão, Ana I ^d   Rocha Rodrigues, Sílvia ^a   Viscor, Ginés ^c   Torrella, J Ramon ^c   Ferreira, Rita ^d   Oliveira, Paulo J ^b   Magalhães, José ^a   Ascensão, António ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF COIMBRA   (Portugal)

^c UNIVERSITY OF BARCELONA   (Spain)

^d UNIVERSITY OF AVEIRO   (Portugal)

Author keywords

Adriamycin; Bioenergetics; Cardioprotection; Exercise; Oxidative damage

Indexed keywords

ACONITATE HYDRATASE; CARBONYL DERIVATIVE; CELL PROTEIN; COMPLEX V; DOXORUBICIN; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL TRANSCRIPTION FACTOR A; OXIDOREDUCTASE; P66SHC PROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SIRTUIN 3; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2; ANTINEOPLASTIC ANTIBIOTIC; CARDIOTOXIN;

ACETYLATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ULTRASTRUCTURE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; EXERCISE; HEART MITOCHONDRION; HEART PROTECTION; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRIAL TOXICITY; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; RAT; TREADMILL EXERCISE; ANIMAL; ENERGY METABOLISM; HUMAN; SPRAGUE DAWLEY RAT;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; CARDIOTOXINS; DOXORUBICIN; ENERGY METABOLISM; HUMANS; MALE; OXIDATIVE STRESS; PHYSICAL CONDITIONING, ANIMAL; RATS, SPRAGUE-DAWLEY;

EID: 84910599790     PISSN: 15677249     EISSN: 18728278     Source Type: Journal    
DOI: 10.1016/j.mito.2014.10.008     Document Type: Article

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