High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain

Human Molecular Genetics

Volumn 11, Issue 2, 2002, Pages 133-145

  Lin, Michael T ^a   Simon, David K ^b   Ahn, Colette H ^a   Kim, Lauren M ^a   Flint Beal, M ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE; MITOCHONDRIAL DNA;

ADULT; AGING; ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ARTICLE; BRAIN MITOCHONDRION; CLINICAL ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DETERIORATION; DNA SEQUENCE; ENZYME ACTIVITY; FEMALE; HUMAN; HUMAN TISSUE; MALE; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; OXIDATION; POINT MUTATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSEUDOGENE; SOMATIC MUTATION;

EID: 0037081814     PISSN: 09646906     EISSN: None     Source Type: Journal    
DOI: 10.1093/hmg/11.2.133     Document Type: Article

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