Intraneuronal Aβ accumulation precedes plaque formation in β-amyloid precursor protein and presenilin-1 double-transgenic mice

Neuroscience Letters

Volumn 306, Issue 1-2, 2001, Pages 116-120

  Wirths, Oliver ^a   Multhaup, Gerd ^b   Czech, Christian ^c   Blanchard, Véronique ^c   Moussaoui, Saliha ^c   Tremp, Günter ^c   Pradier, Laurent ^c   Beyreuther, Konrad ^b   Bayer, Thomas A ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

^c SANOFI   (France)

Author keywords

Immunohistochemistry; Intraneuronal Abeta; Platelet derived growth factor ; Post mortem; Transgenic mouse; Western blot

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; MUTANT PROTEIN; PRESENILIN 1; MEMBRANE PROTEIN; PSEN1 PROTEIN, HUMAN;

AGED; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; BRAIN REGION; CHRONIC DISEASE; CLINICAL FEATURE; CONTROLLED STUDY; CORRELATION FUNCTION; HIPPOCAMPUS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MOUSE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENILE PLAQUE; TISSUE DISTRIBUTION; TRANSGENIC MOUSE; ANIMAL; BRAIN; BRAIN CORTEX; GENETICS; GLIOSIS; HUMAN; METABOLISM; MUTATION; NERVE CELL; PATHOLOGY; PATHOPHYSIOLOGY;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BRAIN; CEREBRAL CORTEX; GLIOSIS; HIPPOCAMPUS; HUMANS; IMMUNOHISTOCHEMISTRY; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; MUTATION; NEURONS; PRESENILIN-1; SENILE PLAQUES;

EID: 0035933279     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)01876-6     Document Type: Article

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