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Volumn 2016, Issue , 2016, Pages

Sulforaphane and Other Nutrigenomic Nrf2 Activators: Can the Clinician's Expectation Be Matched by the Reality?

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CHEMICAL COMPOUNDS; DETOXIFICATION; DIETARY SUPPLEMENTS; FLAVONOIDS; GENES; NUTRITION; PLANTS (BOTANY); TRANSCRIPTION;

EID: 84956697082     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2016/7857186     Document Type: Review
Times cited : (198)

References (170)
  • 1
    • 0030948595 scopus 로고    scopus 로고
    • A prospective discussion of past international nutrition catastrophes-indications for the future
    • R. L. Swank, "A prospective discussion of past international nutrition catastrophes-indications for the future," Nutrition, vol. 13, no. 4, pp. 344-348, 1997.
    • (1997) Nutrition , vol.13 , Issue.4 , pp. 344-348
    • Swank, R.L.1
  • 2
    • 84891035918 scopus 로고    scopus 로고
    • Health-promoting components of fruits and vegetables in the diet
    • R. H. Liu, "Health-promoting components of fruits and vegetables in the diet," Advances in Nutrition, vol. 4, no. 3, pp. 384S-392S, 2013.
    • (2013) Advances in Nutrition , vol.4 , Issue.3 , pp. 384S-392S
    • Liu, R.H.1
  • 3
    • 84868104205 scopus 로고    scopus 로고
    • Novel concepts of broccoli sulforaphanes and disease: Induction of phase II antioxidant and detoxification enzymes by enhanced-glucoraphanin broccoli
    • D. James, S. Devaraj, P. Bellur, S. Lakkanna, J. Vicini, and S. Boddupalli, "Novel concepts of broccoli sulforaphanes and disease: induction of phase II antioxidant and detoxification enzymes by enhanced-glucoraphanin broccoli," Nutrition Reviews, vol. 70, no. 11, pp. 654-665, 2012.
    • (2012) Nutrition Reviews , vol.70 , Issue.11 , pp. 654-665
    • James, D.1    Devaraj, S.2    Bellur, P.3    Lakkanna, S.4    Vicini, J.5    Boddupalli, S.6
  • 5
    • 34547989732 scopus 로고    scopus 로고
    • Personalised nutrition: Status and perspectives
    • H. -G. Joost, M. J. Gibney, K. D. Cashman et al. , "Personalised nutrition: status and perspectives," British Journal of Nutrition, vol. 98, no. 1, pp. 26-31, 2007.
    • (2007) British Journal of Nutrition , vol.98 , Issue.1 , pp. 26-31
    • Joost, H.-G.1    Gibney, M.J.2    Cashman, K.D.3
  • 6
    • 84884710136 scopus 로고    scopus 로고
    • Extraction, chemical characterization and biological activity determination of broccoli health promoting compounds
    • A. M. Ares, M. J. Nozal, and J. Bernal, "Extraction, chemical characterization and biological activity determination of broccoli health promoting compounds," Journal of Chromatography A, vol. 1313, pp. 78-95, 2013.
    • (2013) Journal of Chromatography A , vol.1313 , pp. 78-95
    • Ares, A.M.1    Nozal, M.J.2    Bernal, J.3
  • 7
    • 38549136863 scopus 로고    scopus 로고
    • Polyphenolic phytochemicals-just antioxidants or much more?
    • D. E. Stevenson and R. D. Hurst, "Polyphenolic phytochemicals-just antioxidants or much more?" Cellular and Molecular Life Sciences, vol. 64, no. 22, pp. 2900-2916, 2007.
    • (2007) Cellular and Molecular Life Sciences , vol.64 , Issue.22 , pp. 2900-2916
    • Stevenson, D.E.1    Hurst, R.D.2
  • 8
    • 77956170123 scopus 로고    scopus 로고
    • Polyphenols and health: Update and perspectives
    • H. Sies, "Polyphenols and health: update and perspectives," Archives of Biochemistry and Biophysics, vol. 501, no. 1, pp. 2-5, 2010.
    • (2010) Archives of Biochemistry and Biophysics , vol.501 , Issue.1 , pp. 2-5
    • Sies, H.1
  • 9
    • 13844281685 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
    • C. Manach, G. Williamson, C. Morand, A. Scalbert, and C. Rémésy, "Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies," The American Journal of Clinical Nutrition, vol. 81,no. 1, supplement,pp. 230S-242S, 2005.
    • (2005) The American Journal of Clinical Nutrition , vol.81 , Issue.1 , pp. 230S-242S
    • Manach, C.1    Williamson, G.2    Morand, C.3    Scalbert, A.4    Rémésy, C.5
  • 10
    • 48349140474 scopus 로고    scopus 로고
    • Are polyphenols antioxidants or pro-oxidants? What do we learn from cell culture and in vivo studies?
    • B. Halliwell, "Are polyphenols antioxidants or pro-oxidants? What do we learn from cell culture and in vivo studies?" Archives of Biochemistry and Biophysics, vol. 476, no. 2, pp. 107-112, 2008.
    • (2008) Archives of Biochemistry and Biophysics , vol.476 , Issue.2 , pp. 107-112
    • Halliwell, B.1
  • 11
    • 46949094048 scopus 로고    scopus 로고
    • Hormesis: Why it is important to toxicology and toxicologists
    • E. J. Calabrese, "Hormesis: why it is important to toxicology and toxicologists," Environmental Toxicology and Chemistry, vol. 27, no. 7, pp. 1451-1474, 2008.
    • (2008) Environmental Toxicology and Chemistry , vol.27 , Issue.7 , pp. 1451-1474
    • Calabrese, E.J.1
  • 12
    • 84945346213 scopus 로고    scopus 로고
    • Phytochemical compounds and protection from cardiovascular diseases: A state of the art
    • Article ID918069, 17 pages
    • B. Pagliaro, C. Santolamazza, F. Simonelli, and S. Rubattu, "Phytochemical compounds and protection from cardiovascular diseases: a state of the art," Bio Med Research International, vol. 2015, Article ID918069, 17 pages, 2015.
    • (2015) Bio Med Research International , vol.2015
    • Pagliaro, B.1    Santolamazza, C.2    Simonelli, F.3    Rubattu, S.4
  • 13
    • 77953744137 scopus 로고    scopus 로고
    • Dietary constituents of broccoli and other cruciferous vegetables: Implications for prevention and therapy of cancer
    • I. Herr and M. W. Büchler, "Dietary constituents of broccoli and other cruciferous vegetables: implications for prevention and therapy of cancer," Cancer Treatment Reviews, vol. 36, no. 5, pp. 377-383, 2010.
    • (2010) Cancer Treatment Reviews , vol.36 , Issue.5 , pp. 377-383
    • Herr, I.1    Büchler, M.W.2
  • 14
    • 84874489560 scopus 로고    scopus 로고
    • Keap1-Nrf2 signaling: A target for cancer prevention by sulforaphane
    • T. W. Kensler, P. A. Egner, A. S. Agyeman et al. , "Keap1-Nrf2 signaling: a target for cancer prevention by sulforaphane," Topics in Current Chemistry, vol. 329, pp. 163-178, 2013.
    • (2013) Topics in Current Chemistry , vol.329 , pp. 163-178
    • Kensler, T.W.1    Egner, P.A.2    Agyeman, A.S.3
  • 15
    • 47949102659 scopus 로고    scopus 로고
    • Antiproliferative and antioxidant activities of common vegetables: A comparative study
    • D. Boivin, S. Lamy, S. Lord-Dufour et al. , "Antiproliferative and antioxidant activities of common vegetables: a comparative study," Food Chemistry, vol. 112, no. 2, pp. 374-380, 2009.
    • (2009) Food Chemistry , vol.112 , Issue.2 , pp. 374-380
    • Boivin, D.1    Lamy, S.2    Lord-Dufour, S.3
  • 16
    • 34047136753 scopus 로고    scopus 로고
    • Cruciferous vegetables and human cancer risk: Epidemiologic evidence and mechanistic basis
    • J. V. Higdon, B. Delage, D. E. Williams, and R. H. Dashwood, "Cruciferous vegetables and human cancer risk: epidemiologic evidence and mechanistic basis," Pharmacological Research, vol. 55, no. 3, pp. 224-236, 2007.
    • (2007) Pharmacological Research , vol.55 , Issue.3 , pp. 224-236
    • Higdon, J.V.1    Delage, B.2    Williams, D.E.3    Dashwood, R.H.4
  • 17
    • 79959385852 scopus 로고    scopus 로고
    • Cruciferous vegetable consumption is associated with a reduced risk of total and cardiovascular disease mortality
    • X. Zhang, X. -O. Shu, Y. -B. Xiang et al. , "Cruciferous vegetable consumption is associated with a reduced risk of total and cardiovascular disease mortality," American Journal of Clinical Nutrition, vol. 94, no. 1, pp. 240-246, 2011.
    • (2011) American Journal of Clinical Nutrition , vol.94 , Issue.1 , pp. 240-246
    • Zhang, X.1    Shu, X.-O.2    Xiang, Y.-B.3
  • 18
    • 18244409629 scopus 로고    scopus 로고
    • Fruit and vegetable consumption and cognitive decline in aging women
    • J. H. Kang, A. Ascherio, and F. Grodstein, "Fruit and vegetable consumption and cognitive decline in aging women," Annals of Neurology, vol. 57, no. 5, pp. 713-720, 2005.
    • (2005) Annals of Neurology , vol.57 , Issue.5 , pp. 713-720
    • Kang, J.H.1    Ascherio, A.2    Grodstein, F.3
  • 21
    • 0034601232 scopus 로고    scopus 로고
    • Inhibition of benzo[a]pyrene-and 1,6-dinitropyrene-DNA adduct formation in human mammary epithelial cells bydibenzoylmethane and sulforaphane
    • K. Singletary and C. MacDonald, "Inhibition of benzo[a]pyrene-and 1,6-dinitropyrene-DNA adduct formation in human mammary epithelial cells bydibenzoylmethane and sulforaphane," Cancer Letters, vol. 155, no. 1, pp. 47-54, 2000.
    • (2000) Cancer Letters , vol.155 , Issue.1 , pp. 47-54
    • Singletary, K.1    MacDonald, C.2
  • 22
    • 75149174413 scopus 로고    scopus 로고
    • Depurinating estrogen-DNA adducts in the etiology and prevention of breast and other human cancers
    • E. L. Cavalieri and E. G. Rogan, "Depurinating estrogen-DNA adducts in the etiology and prevention of breast and other human cancers," Future Oncology, vol. 6, no. 1, pp. 75-91, 2010.
    • (2010) Future Oncology , vol.6 , Issue.1 , pp. 75-91
    • Cavalieri, E.L.1    Rogan, E.G.2
  • 23
    • 84896378471 scopus 로고    scopus 로고
    • Systems toxicology approach to understand the kinetics of benzo(a)pyrene uptake, biotransformation, and DNA adduct formation in a liver cell model
    • D. J. Madureira, F. T. Weiss, P. Van Midwoud, D. E. Helbling, S. J. Sturla, and K. Schirmer, "Systems toxicology approach to understand the kinetics of benzo(a)pyrene uptake, biotransformation, and DNA adduct formation in a liver cell model," Chemical Research in Toxicology, vol. 27, no. 3, pp. 443-453, 2014.
    • (2014) Chemical Research in Toxicology , vol.27 , Issue.3 , pp. 443-453
    • Madureira, D.J.1    Weiss, F.T.2    Van Midwoud, P.3    Helbling, D.E.4    Sturla, S.J.5    Schirmer, K.6
  • 24
    • 0028061444 scopus 로고
    • Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the -globin locus control region
    • P. Moi, K. Chan, I. Asunis, A. Cao, and Y. W. Kan, "Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the -globin locus control region," Proceedings of the National Academy of Sciences of the United States of America, vol. 91, no. 21, pp. 9926-9930, 1994.
    • (1994) Proceedings of the National Academy of Sciences of the United States of America , vol.91 , Issue.21 , pp. 9926-9930
    • Moi, P.1    Chan, K.2    Asunis, I.3    Cao, A.4    Kan, Y.W.5
  • 25
    • 21744445077 scopus 로고    scopus 로고
    • Nrf2, a multi-organ protector?
    • J. -M. Lee, J. Li, D. A. Johnson et al. , "Nrf2, a multi-organ protector?" The FASEB Journal, vol. 19, no. 9, pp. 1061-1066, 2005.
    • (2005) The FASEB Journal , vol.19 , Issue.9 , pp. 1061-1066
    • Lee, J.-M.1    Li, J.2    Johnson, D.A.3
  • 26
    • 77958115724 scopus 로고    scopus 로고
    • Regulation of the Nrf2-keap1 antioxidant response by the ubiquitin proteasome system: An insight into cullin-ring ubiquitin ligases
    • N. F. Villeneuve, A. Lau, and D. D. Zhang, "Regulation of the Nrf2-keap1 antioxidant response by the ubiquitin proteasome system: an insight into cullin-ring ubiquitin ligases," Antioxidants & Redox Signaling, vol. 13, no. 11, pp. 1699-1712, 2010.
    • (2010) Antioxidants & Redox Signaling , vol.13 , Issue.11 , pp. 1699-1712
    • Villeneuve, N.F.1    Lau, A.2    Zhang, D.D.3
  • 27
    • 33645993864 scopus 로고    scopus 로고
    • Quinone reductase induction as a biomarker for cancer chemoprevention
    • M. Cuendet, C. P. Oteham, R. C. Moon, and J. M. Pezzuto, "Quinone reductase induction as a biomarker for cancer chemoprevention," Journal of Natural Products, vol. 69, no. 3, pp. 460-463, 2006.
    • (2006) Journal of Natural Products , vol.69 , Issue.3 , pp. 460-463
    • Cuendet, M.1    Oteham, C.P.2    Moon, R.C.3    Pezzuto, J.M.4
  • 28
    • 1942520367 scopus 로고    scopus 로고
    • Nrf2 signaling in coordinated activation of antioxidant gene expression
    • A. K. Jaiswal, "Nrf2 signaling in coordinated activation of antioxidant gene expression,"FreeRadical Biologyand Medicine, vol. 36, no. 10, pp. 1199-1207, 2004.
    • (2004) FreeRadical Biologyand Medicine , vol.36 , Issue.10 , pp. 1199-1207
    • Jaiswal, A.K.1
  • 29
    • 2342514015 scopus 로고    scopus 로고
    • An important role of Nrf2-ARE pathway in the cellular defense mechanism
    • J. -M. Lee and J. A. Johnson, "An important role of Nrf2-ARE pathway in the cellular defense mechanism," Journal of Biochemistry and Molecular Biology, vol. 37, no. 2, pp. 139-143, 2004.
    • (2004) Journal of Biochemistry and Molecular Biology , vol.37 , Issue.2 , pp. 139-143
    • Lee, J.-M.1    Johnson, J.A.2
  • 30
    • 56249106571 scopus 로고    scopus 로고
    • Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals
    • Y. -J. Surh, J. K. Kundu, and H. -K. Na, "Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals," Planta Medica, vol. 74, no. 13, pp. 1526-1539, 2008.
    • (2008) Planta Medica , vol.74 , Issue.13 , pp. 1526-1539
    • Surh, Y.-J.1    Kundu, J.K.2    Na, H.-K.3
  • 31
  • 32
    • 84861746200 scopus 로고    scopus 로고
    • The emerging harmof antioxidants in carcinogenesis
    • C. Hart, R. Cohen, M. Norwood, and J. Stebbing, "The emerging harmof antioxidants in carcinogenesis," Future Oncology, vol. 8, no. 5, pp. 535-548, 2012.
    • (2012) Future Oncology , vol.8 , Issue.5 , pp. 535-548
    • Hart, C.1    Cohen Norwood M, R.2    Stebbing, J.3
  • 33
    • 33746889956 scopus 로고    scopus 로고
    • Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice
    • R. Hu, C. Xu, G. Shen et al. , "Gene expression profiles induced by cancer chemopreventive isothiocyanate sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (-/-) mice," Cancer Letters, vol. 243, no. 2, pp. 170-192, 2006.
    • (2006) Cancer Letters , vol.243 , Issue.2 , pp. 170-192
    • Hu, R.1    Xu, C.2    Shen, G.3
  • 34
    • 0037424262 scopus 로고    scopus 로고
    • Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway: Identification of novel gene clusters for cell survival
    • M. -K. Kwak, N. Wakabayashi, K. Itoh, H. Motohashi, M. Yamamoto, and T. W. Kensler, "Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway: identification of novel gene clusters for cell survival," The Journal of Biological Chemistry, vol. 278, no. 10, pp. 8135-8145, 2003.
    • (2003) The Journal of Biological Chemistry , vol.278 , Issue.10 , pp. 8135-8145
    • Kwak, M.-K.1    Wakabayashi, N.2    Itoh, K.3    Motohashi, H.4    Yamamoto, M.5    Kensler, T.W.6
  • 35
    • 84893744320 scopus 로고    scopus 로고
    • Oxidative stress, prooxidants, and antioxidants: The interplay
    • Article ID 761264, 19 pages
    • A. Rahal, A. Kumar, V. Singh et al. , "Oxidative stress, prooxidants, and antioxidants: the interplay," Bio Med Research International, vol. 2014,Article ID 761264, 19 pages, 2014.
    • (2014) Bio Med Research International , vol.2014
    • Rahal, A.1    Kumar, A.2    Singh, V.3
  • 36
    • 63049118830 scopus 로고    scopus 로고
    • Antioxidant and pro-oxidant capacities of ITCs
    • L. Valgimigli and R. Iori, "Antioxidant and pro-oxidant capacities of ITCs," Environmental and MolecularMutagenesis, vol. 50, no. 3, pp. 222-237, 2009.
    • (2009) Environmental and MolecularMutagenesis , vol.50 , Issue.3 , pp. 222-237
    • Valgimigli, L.1    Iori, R.2
  • 37
    • 0034854057 scopus 로고    scopus 로고
    • Potent induction of phase 2 enzymes in human prostate cells by sulforaphane
    • J. D. Brooks, V. G. Paton, and G. Vidanes, "Potent induction of phase 2 enzymes in human prostate cells by sulforaphane," Cancer Epidemiology Biomarkers and Prevention, vol. 10, no. 9, pp. 949-954, 2001.
    • (2001) Cancer Epidemiology Biomarkers and Prevention , vol.10 , Issue.9 , pp. 949-954
    • Brooks, J.D.1    Paton, V.G.2    Vidanes, G.3
  • 38
    • 27644553527 scopus 로고    scopus 로고
    • Involvement of c-Jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by sulforaphane in DU145 prostate cancer cells
    • S. -D. Cho, G. Li, H. Hu et al. , "Involvement of c-Jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by sulforaphane in DU145 prostate cancer cells," Nutrition and Cancer, vol. 52, no. 2, pp. 213-224, 2005.
    • (2005) Nutrition and Cancer , vol.52 , Issue.2 , pp. 213-224
    • Cho, S.-D.1    Li, G.2    Hu, H.3
  • 39
    • 84885448423 scopus 로고    scopus 로고
    • Sulforaphane is superior to glucoraphanin in modulating carcinogen-metabolising enzymes in Hep G2 cells
    • A. F. Abdull Razis and N. M. Noor, "Sulforaphane is superior to glucoraphanin in modulating carcinogen-metabolising enzymes in Hep G2 cells," Asian Pacific Journal of Cancer Prevention, vol. 14, no. 7, pp. 4235-4238, 2013.
    • (2013) Asian Pacific Journal of Cancer Prevention , vol.14 , Issue.7 , pp. 4235-4238
    • Abdull Razis, A.F.1    Noor, N.M.2
  • 40
    • 0029077105 scopus 로고
    • Studies on the mechanism of myrosinase-investigation of the effect of glycosyl acceptors on enzyme activity
    • M. G. Botti, M. G. Taylor, and N. P. Botting, "Studies on the mechanism of myrosinase-investigation of the effect of glycosyl acceptors on enzyme activity," Journal of Biological Chemistry, vol. 270, no. 35, pp. 20530-20535, 1995.
    • (1995) Journal of Biological Chemistry , vol.270 , Issue.35 , pp. 20530-20535
    • Botti, M.G.1    Taylor, M.G.2    Botting, N.P.3
  • 41
    • 77955656454 scopus 로고    scopus 로고
    • Preparation and stability investigation of the inclusion complex of sulforaphane with hydroxypropyl-β-cyclodextrin
    • H. Wu, H. Liang, Q. Yuan, T. Wang, and X. Yan, "Preparation and stability investigation of the inclusion complex of sulforaphane with hydroxypropyl-β-cyclodextrin," Carbohydrate Polymers, vol. 82, no. 3, pp. 613-617, 2010.
    • (2010) Carbohydrate Polymers , vol.82 , Issue.3 , pp. 613-617
    • Wu, H.1    Liang, H.2    Yuan, Q.3    Wang, T.4    Yan, X.5
  • 42
    • 80054981857 scopus 로고    scopus 로고
    • Comparison of isothiocyanate metabolite levels and histone deacetylase activity in human subjects consuming broccoli sprouts or broccoli supplement
    • J. D. Clarke, K. Riedl, D. Bella, S. J. Schwartz, J. F. Stevens, and E. Ho, "Comparison of isothiocyanate metabolite levels and histone deacetylase activity in human subjects consuming broccoli sprouts or broccoli supplement," Journal of Agricultural and Food Chemistry, vol. 59, no. 20, pp. 10955-10963, 2011.
    • (2011) Journal of Agricultural and Food Chemistry , vol.59 , Issue.20 , pp. 10955-10963
    • Clarke, J.D.1    Riedl, K.2    Bella, D.3    Schwartz, S.J.4    Stevens, J.F.5    Ho, E.6
  • 43
    • 84877588109 scopus 로고    scopus 로고
    • Comparison of bioactive phytochemical content and release of isothiocyanates in selected brassica sprouts
    • G. R. De Nicola, M. Bagatta, E. Pagnotta et al. , "Comparison of bioactive phytochemical content and release of isothiocyanates in selected brassica sprouts," Food Chemistry, vol. 141, no. 1, pp. 297-303, 2013.
    • (2013) Food Chemistry , vol.141 , Issue.1 , pp. 297-303
    • De Nicola, G.R.1    Bagatta, M.2    Pagnotta, E.3
  • 45
    • 1242274623 scopus 로고    scopus 로고
    • Chemical structures of inducers of nicotinamide quinone oxidoreductase 1 (NQO1)
    • A. T. Dinkova-Kostova, J. W. Fahey, and P. Talalay, "Chemical structures of inducers of nicotinamide quinone oxidoreductase 1 (NQO1),"Methods in Enzymology, vol. 382, pp. 423-448, 2004.
    • (2004) Methods in Enzymology , vol.382 , pp. 423-448
    • Dinkova-Kostova, A.T.1    Fahey, J.W.2    Talalay, P.3
  • 46
    • 38149062008 scopus 로고    scopus 로고
    • Are we getting enough sulfur in our diet?
    • article 24
    • M. E. Nimni, B. Han, and F. Cordoba, "Are we getting enough sulfur in our diet?" Nutrition and Metabolism, vol. 4, article 24, 2007.
    • (2007) Nutrition and Metabolism , vol.4
    • Nimni, M.E.1    Han, B.2    Cordoba, F.3
  • 47
    • 0031849275 scopus 로고    scopus 로고
    • Immunonutrition: Role of sulfur amino acids, related amino acids, and polyamines
    • R. F. Grimble and G. K. Grimble, "Immunonutrition: role of sulfur amino acids, related amino acids, and polyamines," Nutrition, vol. 14, no. 7-8, pp. 605-610, 1998.
    • (1998) Nutrition , vol.14 , Issue.7-8 , pp. 605-610
    • Grimble, R.F.1    Grimble, G.K.2
  • 48
    • 77957725492 scopus 로고    scopus 로고
    • Vegetarian diets and public health: Biomarker and redox connections
    • I. F. F. Benzie and S. Wachtel-Galor, "Vegetarian diets and public health: biomarker and redox connections," Antioxidants & Redox Signaling, vol. 13, no. 10, pp. 1575-1591, 2010.
    • (2010) Antioxidants & Redox Signaling , vol.13 , Issue.10 , pp. 1575-1591
    • Benzie, I.F.F.1    Wachtel-Galor, S.2
  • 49
    • 0030931522 scopus 로고    scopus 로고
    • Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens
    • J. W. Fahey, Y. Zhang, and P. Talalay, "Broccoli sprouts: an exceptionally rich source of inducers of enzymes that protect against chemical carcinogens," Proceedings of the National Academy of Sciences of the United States of America, vol. 94, no. 19, pp. 10367-10372, 1997.
    • (1997) Proceedings of the National Academy of Sciences of the United States of America , vol.94 , Issue.19 , pp. 10367-10372
    • Fahey, J.W.1    Zhang, Y.2    Talalay, P.3
  • 50
    • 0031894295 scopus 로고    scopus 로고
    • Indole-3-carbinol: Anticarcinogen or tumor promoter in brassica vegetables?
    • R. H. Dashwood, "Indole-3-carbinol: anticarcinogen or tumor promoter in brassica vegetables?" Chemico-Biological Interactions, vol. 110, no. 1-2, pp. 1-5, 1998.
    • (1998) Chemico-Biological Interactions , vol.110 , Issue.1-2 , pp. 1-5
    • Dashwood, R.H.1
  • 51
    • 0038049147 scopus 로고    scopus 로고
    • Translational strategies for cancer prevention in liver
    • T. W. Kensler, G. -S. Qian, J. -G. Chen, and J. D. Groopman, "Translational strategies for cancer prevention in liver," Nature Reviews Cancer, vol. 3, no. 5, pp. 321-329, 2003.
    • (2003) Nature Reviews Cancer , vol.3 , Issue.5 , pp. 321-329
    • Kensler, T.W.1    Qian, G.-S.2    Chen, J.-G.3    Groopman, J.D.4
  • 52
    • 0028856209 scopus 로고
    • Induction of phase i and phase II drug-metabolizing enzyme mRNA, protein, and activity by BHA, ethoxyquin, and oltipraz
    • T. M. Buetler, E. P. Gallagher, C. Wang, D. L. Stahl, J. D. Hayes, and D. L. Eaton, "Induction of phase I and phase II drug-metabolizing enzyme mRNA, protein, and activity by BHA, ethoxyquin, and oltipraz," Toxicology and Applied Pharmacology, vol. 135, no. 1, pp. 45-57, 1995.
    • (1995) Toxicology and Applied Pharmacology , vol.135 , Issue.1 , pp. 45-57
    • Buetler, T.M.1    Gallagher, E.P.2    Wang, C.3    Stahl, D.L.4    Hayes, J.D.5    Eaton, D.L.6
  • 53
    • 34447299123 scopus 로고    scopus 로고
    • Identification of polymorphic antioxidant response elements in the human genome
    • X. Wang, D. J. Tomso, B. N. Chorley et al. , "Identification of polymorphic antioxidant response elements in the human genome," Human Molecular Genetics, vol. 16, no. 10, pp. 1188-1200, 2007.
    • (2007) Human Molecular Genetics , vol.16 , Issue.10 , pp. 1188-1200
    • Wang, X.1    Tomso, D.J.2    Chorley, B.N.3
  • 54
    • 0031577292 scopus 로고    scopus 로고
    • An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
    • K. Itoh, T. Chiba, S. Takahashi et al. , "An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements," Biochemical and Biophysical Research Communications, vol. 236, no. 2, pp. 313-322, 1997.
    • (1997) Biochemical and Biophysical Research Communications , vol.236 , Issue.2 , pp. 313-322
    • Itoh, K.1    Chiba, T.2    Takahashi, S.3
  • 55
    • 0037462651 scopus 로고    scopus 로고
    • Degradation of transcription factorNrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium
    • D. Stewart, E. Killeen, R. Naquin, S. Alam, and J. Alam, "Degradation of transcription factorNrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium," The Journal of Biological Chemistry, vol. 278, no. 4, pp. 2396-2402, 2003.
    • (2003) The Journal of Biological Chemistry , vol.278 , Issue.4 , pp. 2396-2402
    • Stewart, D.1    Killeen, E.2    Naquin, R.3    Alam, S.4    Alam, J.5
  • 56
    • 9944255781 scopus 로고    scopus 로고
    • Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome
    • Y. Katoh, K. Iida, M. -I. Kang et al. , "Evolutionary conserved N-terminal domain of Nrf2 is essential for the Keap1-mediated degradation of the protein by proteasome," Archives of Biochemistry and Biophysics, vol. 433, no. 2, pp. 342-350, 2005.
    • (2005) Archives of Biochemistry and Biophysics , vol.433 , Issue.2 , pp. 342-350
    • Katoh, Y.1    Iida, K.2    Kang, M.-I.3
  • 57
    • 3543008924 scopus 로고    scopus 로고
    • Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
    • A. Kobayashi, M. -I. Kang, H. Okawa et al. , "Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2," Molecular and Cellular Biology, vol. 24, no. 16, pp. 7130-7139, 2004.
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.16 , pp. 7130-7139
    • Kobayashi, A.1    Kang, M.-I.2    Okawa, H.3
  • 58
    • 78751703950 scopus 로고    scopus 로고
    • Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution
    • K. Taguchi, H. Motohashi, and M. Yamamoto, "Molecular mechanisms of the Keap1-Nrf2 pathway in stress response and cancer evolution," Genes to Cells, vol. 16, no. 2, pp. 123-140, 2011.
    • (2011) Genes to Cells , vol.16 , Issue.2 , pp. 123-140
    • Taguchi, K.1    Motohashi, H.2    Yamamoto, M.3
  • 60
    • 54449093352 scopus 로고    scopus 로고
    • The hepatotoxic metabolite of acetaminophen directly activates the keap1-Nrf2 cell defense system
    • I. M. Copple, C. E. Goldring, R. E. Jenkins et al. , "The hepatotoxic metabolite of acetaminophen directly activates the keap1-Nrf2 cell defense system," Hepatology, vol. 48, no. 4, pp. 1292-1301, 2008.
    • (2008) Hepatology , vol.48 , Issue.4 , pp. 1292-1301
    • Copple, I.M.1    Goldring, C.E.2    Jenkins, R.E.3
  • 61
    • 79751525643 scopus 로고    scopus 로고
    • Role of the Nrf2-ARE pathway in early brain injury after experimental subarachnoid hemorrhage
    • G. Chen, Q. Fang, J. Zhang, D. Zhou, and Z. Wang, "Role of the Nrf2-ARE pathway in early brain injury after experimental subarachnoid hemorrhage," Journal of Neuroscience Research, vol. 89, no. 4, pp. 515-523, 2011.
    • (2011) Journal of Neuroscience Research , vol.89 , Issue.4 , pp. 515-523
    • Chen, G.1    Fang, Q.2    Zhang, J.3    Zhou, D.4    Wang, Z.5
  • 62
    • 34247606510 scopus 로고    scopus 로고
    • Molecular basis for chemoprevention by sulforaphane: A comprehensive review
    • N. Juge, R. F. Mithen, and M. Traka, "Molecular basis for chemoprevention by sulforaphane: a comprehensive review," Cellular and Molecular Life Sciences, vol. 64, no. 9, pp. 1105-1127, 2007.
    • (2007) Cellular and Molecular Life Sciences , vol.64 , Issue.9 , pp. 1105-1127
    • Juge, N.1    Mithen, R.F.2    Traka, M.3
  • 64
    • 24144469328 scopus 로고    scopus 로고
    • Induction of NAD(P)H quinone oxidoreductase by vegetables widely consumed in Catalonia, Spain
    • N. Laso, S. Mas, M. J. Lafuente et al. , "Induction of NAD(P)H quinone oxidoreductase by vegetables widely consumed in Catalonia, Spain," Nutrition and Cancer, vol. 52, no. 1, pp. 49-58, 2005.
    • (2005) Nutrition and Cancer , vol.52 , Issue.1 , pp. 49-58
    • Laso, N.1    Mas, S.2    Lafuente, M.J.3
  • 65
    • 0034490852 scopus 로고    scopus 로고
    • Chemoprotection against cancer by induction of Phase 2 enzymes
    • P. Talalay, "Chemoprotection against cancer by induction of Phase 2 enzymes," Bio Factors, vol. 12, no. 1-4, pp. 5-11, 2000.
    • (2000) Bio Factors , vol.12 , Issue.1-4 , pp. 5-11
    • Talalay, P.1
  • 66
    • 0035909947 scopus 로고    scopus 로고
    • Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: The indirect antioxidant effects of sulforaphane
    • X. Gao, A. T. Dinkova-Kostova, and P. Talalay, "Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: the indirect antioxidant effects of sulforaphane," Proceedings of the National Academy of Sciences of the United States of America, vol. 98, no. 26, pp. 15221-15226, 2001.
    • (2001) Proceedings of the National Academy of Sciences of the United States of America , vol.98 , Issue.26 , pp. 15221-15226
    • Gao, X.1    Dinkova-Kostova, A.T.2    Talalay, P.3
  • 67
    • 84929505243 scopus 로고    scopus 로고
    • Nrf2, a master regulator of detoxification and also antioxidant, anti-inflammatory and other cytoprotective mechanisms, is raised by health promoting factors
    • M. L. Pall and S. Levine, "Nrf2, a master regulator of detoxification and also antioxidant, anti-inflammatory and other cytoprotective mechanisms, is raised by health promoting factors," Sheng Li Xue Bao, vol. 67, no. 1, pp. 1-18, 2015.
    • (2015) Sheng Li Xue Bao , vol.67 , Issue.1 , pp. 1-18
    • Pall, M.L.1    Levine, S.2
  • 68
    • 84885460677 scopus 로고    scopus 로고
    • Acroleinexposure suppresses antigen-induced pulmonary inflammation
    • article 107
    • P. C. Spiess, D. Kasahara,A. Habibovic et al. , "Acroleinexposure suppresses antigen-induced pulmonary inflammation," Respiratory Research, vol. 14, article 107, 2013.
    • (2013) Respiratory Research , vol.14
    • Spiess, P.C.1    Kasahara, A.2    Habibovic, D.3
  • 69
    • 53449101213 scopus 로고    scopus 로고
    • Molecular mechanisms of natural products in chemoprevention: Induction of cytoprotective enzymes by Nrf2,"Molecular
    • A. L. Eggler, K. A. Gay, and A. D. Mesecar, "Molecular mechanisms of natural products in chemoprevention: induction of cytoprotective enzymes by Nrf2,"Molecular Nutrition and Food Research, vol. 52, supplement 1, pp. S84-S94, 2008.
    • (2008) Nutrition and Food Research , vol.52 , pp. S84-S94
    • Eggler, A.L.1    Gay, K.A.2    Mesecar, A.D.3
  • 70
    • 0037106099 scopus 로고    scopus 로고
    • Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
    • R. K. Thimmulappa, K. H. Mai, S. Srisuma, T. W. Kensler, M. Yamamoto, and S. Biswal, "Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray," Cancer Research, vol. 62,no. 18, pp. 5196-5203, 2002.
    • (2002) Cancer Research , vol.62 , Issue.18 , pp. 5196-5203
    • Thimmulappa, R.K.1    Mai, K.H.2    Srisuma, S.3    Kensler, T.W.4    Yamamoto, M.5    Biswal, S.6
  • 71
    • 84863040961 scopus 로고    scopus 로고
    • Sulforaphane induces antioxidative and antiproliferative responses by generating reactive oxygen species in human bronchial epithelial BEAS-2B cells
    • Y. -J. Lee and S. -H. Lee, "Sulforaphane induces antioxidative and antiproliferative responses by generating reactive oxygen species in human bronchial epithelial BEAS-2B cells," Journal of Korean Medical Science, vol. 26, no. 11, pp. 1474-1482, 2011.
    • (2011) Journal of Korean Medical Science , vol.26 , Issue.11 , pp. 1474-1482
    • Lee, Y.-J.1    Lee, S.-H.2
  • 72
    • 78650876692 scopus 로고    scopus 로고
    • Vitamin D: Evolutionary, physiological and health perspectives
    • M. F. Holick, "Vitamin D: evolutionary, physiological and health perspectives," Current Drug Targets, vol. 12, no. 1, pp. 4-18, 2011.
    • (2011) Current Drug Targets , vol.12 , Issue.1 , pp. 4-18
    • Holick, M.F.1
  • 73
    • 51249112155 scopus 로고    scopus 로고
    • The dietary histone deacetylase inhibitor sulforaphane induces human β-defensin-2 in intestinal epithelial cells
    • M. Schwab, V. Reynders, S. Loitsch, D. Steinhilber, O. Schröder, and J. Stein, "The dietary histone deacetylase inhibitor sulforaphane induces human β-defensin-2 in intestinal epithelial cells," Immunology, vol. 125, no. 2, pp. 241-251, 2008.
    • (2008) Immunology , vol.125 , Issue.2 , pp. 241-251
    • Schwab, M.1    Reynders, V.2    Loitsch, S.3    Steinhilber, D.4    Schröder, O.5    Stein, J.6
  • 75
    • 1642368362 scopus 로고    scopus 로고
    • Induction of cytoprotective genes through Nrf2/antioxidant response element pathway: A new therapeutic approach for the treatment of inflammatory diseases
    • X. -L. Chen and C. Kunsch, "Induction of cytoprotective genes through Nrf2/antioxidant response element pathway: a new therapeutic approach for the treatment of inflammatory diseases," Current Pharmaceutical Design, vol. 10, no. 8, pp. 879-891, 2004.
    • (2004) Current Pharmaceutical Design , vol.10 , Issue.8 , pp. 879-891
    • Chen, X.-L.1    Kunsch, C.2
  • 76
    • 0032841203 scopus 로고    scopus 로고
    • Antioxidant functions of sulforaphane: A potent inducer of phase II detoxication enzymes
    • J. W. Fahey and P. Talalay, "Antioxidant functions of sulforaphane: a potent inducer of phase II detoxication enzymes," Food and Chemical Toxicology, vol. 37, no. 9-10, pp. 973-979, 1999.
    • (1999) Food and Chemical Toxicology , vol.37 , Issue.9-10 , pp. 973-979
    • Fahey, J.W.1    Talalay, P.2
  • 77
    • 77956171147 scopus 로고    scopus 로고
    • NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector
    • A. T. Dinkova-Kostova and P. Talalay, "NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector," Archives of Biochemistry and Biophysics, vol. 501, no. 1, pp. 116-123, 2010.
    • (2010) Archives of Biochemistry and Biophysics , vol.501 , Issue.1 , pp. 116-123
    • Dinkova-Kostova, A.T.1    Talalay, P.2
  • 79
    • 1542723493 scopus 로고    scopus 로고
    • Decline in transcriptional activity ofNrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid
    • J. H. Suh, S. V. Shenvi, B. M. Dixon et al. , "Decline in transcriptional activity ofNrf2 causes age-related loss of glutathione synthesis, which is reversible with lipoic acid," Proceedings of the NationalAcademy of Sciences of theUnited States ofAmerica, vol. 101, no. 10, pp. 3381-3386, 2004.
    • (2004) Proceedings of the NationalAcademy of Sciences of TheUnited States OfAmerica , vol.101 , Issue.10 , pp. 3381-3386
    • Suh, J.H.1    Shenvi, S.V.2    Dixon, B.M.3
  • 80
    • 84880514122 scopus 로고    scopus 로고
    • Declining signal dependence of Nrf2-MafSregulated gene expression correlates with aging phenotypes
    • M. M. Rahman, G. P. Sykiotis, M. Nishimura, R. Bodmer, and D. Bohmann, "Declining signal dependence of Nrf2-MafSregulated gene expression correlates with aging phenotypes," Aging Cell, vol. 12, no. 4, pp. 554-562, 2013.
    • (2013) Aging Cell , vol.12 , Issue.4 , pp. 554-562
    • Rahman, M.M.1    Sykiotis, G.P.2    Nishimura, M.3    Bodmer, R.4    Bohmann, D.5
  • 81
    • 0033805326 scopus 로고    scopus 로고
    • Persuasive evidence that quinone reductase type 1 (DT diaphorase) protects cells against the toxicity of electrophiles and reactive forms of oxygen
    • A. T. Dinkova-Kostova and P. Talalay, "Persuasive evidence that quinone reductase type 1 (DT diaphorase) protects cells against the toxicity of electrophiles and reactive forms of oxygen," Free Radical Biology and Medicine, vol. 29,no. 3-4, pp. 231-240, 2000.
    • (2000) Free Radical Biology and Medicine , vol.29 , Issue.3-4 , pp. 231-240
    • Dinkova-Kostova, A.T.1    Talalay, P.2
  • 82
    • 84875051043 scopus 로고    scopus 로고
    • Genotoxic bioactivation of constituents of a diesel exhaust particle extract by the human lung
    • M. M. Iba and R. J. Caccavale, "Genotoxic bioactivation of constituents of a diesel exhaust particle extract by the human lung," Environmental and Molecular Mutagenesis, vol. 54, no. 3, pp. 158-171, 2013.
    • (2013) Environmental and Molecular Mutagenesis , vol.54 , Issue.3 , pp. 158-171
    • Iba, M.M.1    Caccavale, R.J.2
  • 83
    • 1242319534 scopus 로고    scopus 로고
    • Upregulation of quinone reductase by glucosinolate hydrolysis products from dietary broccoli
    • E. H. Jeffery and K. E. Stewart, "Upregulation of quinone reductase by glucosinolate hydrolysis products from dietary broccoli," Methods in Enzymology, vol. 382, pp. 457-469, 2004.
    • (2004) Methods in Enzymology , vol.382 , pp. 457-469
    • Jeffery, E.H.1    Stewart, K.E.2
  • 84
    • 2942668508 scopus 로고    scopus 로고
    • AIRarg and AIRgluc as predictors of insulin secretory reserve
    • R. P. Robertson, "AIRarg and AIRgluc as predictors of insulin secretory reserve," Transplantation Proceedings, vol. 36, no. 4, pp. 1040-1041, 2004.
    • (2004) Transplantation Proceedings , vol.36 , Issue.4 , pp. 1040-1041
    • Robertson, R.P.1
  • 85
    • 22844437903 scopus 로고    scopus 로고
    • Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers ofmammalian phase 2 cytoprotective genes
    • J. W. Fahey, K. K. Stephenson, A. T. Dinkova-Kostova, P. A. Egner, T. W. Kensler, and P. Talalay, "Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers ofmammalian phase 2 cytoprotective genes," Carcinogenesis, vol. 26, no. 7, pp. 1247-1255, 2005.
    • (2005) Carcinogenesis , vol.26 , Issue.7 , pp. 1247-1255
    • Fahey, J.W.1    Stephenson, K.K.2    Dinkova-Kostova, A.T.3    Egner, P.A.4    Kensler, T.W.5    Talalay, P.6
  • 86
    • 0032406798 scopus 로고    scopus 로고
    • Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables
    • T. A. Shapiro, J. W. Fahey, K. L. Wade, K. K. Stephenson, and P. Talalay, "Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables," Cancer Epidemiology Biomarkers and Prevention, vol. 7, no. 12, pp. 1091-1100, 1998.
    • (1998) Cancer Epidemiology Biomarkers and Prevention , vol.7 , Issue.12 , pp. 1091-1100
    • Shapiro, T.A.1    Fahey, J.W.2    Wade, K.L.3    Stephenson, K.K.4    Talalay, P.5
  • 87
    • 34248585061 scopus 로고    scopus 로고
    • Role of dietary supplements/ nutraceuticals in chemoprevention through induction of cytoprotective enzymes
    • J. W. Fahey and T. W. Kensler, "Role of dietary supplements/ nutraceuticals in chemoprevention through induction of cytoprotective enzymes," Chemical Research in Toxicology, vol. 20, no. 4, pp. 572-576, 2007.
    • (2007) Chemical Research in Toxicology , vol.20 , Issue.4 , pp. 572-576
    • Fahey, J.W.1    Kensler, T.W.2
  • 88
    • 84870782936 scopus 로고    scopus 로고
    • Quinone reductase (QR) inducers from Andrographis paniculata and identification of molecular target of andrographolide
    • Y. Yuan, L. Ji, L. Luo et al. , "Quinone reductase (QR) inducers from Andrographis paniculata and identification of molecular target of andrographolide," Fitoterapia, vol. 83, no. 8, pp. 1506-1513, 2012.
    • (2012) Fitoterapia , vol.83 , Issue.8 , pp. 1506-1513
    • Yuan, Y.1    Ji, L.2    Luo, L.3
  • 89
    • 59649102647 scopus 로고    scopus 로고
    • Induction of phase II enzyme, quinone reductase, in murine hepatoma cells in vitro by grape extracts and selected phytochemicals
    • J. Yang and R. H. Liu, "Induction of phase II enzyme, quinone reductase, in murine hepatoma cells in vitro by grape extracts and selected phytochemicals," Food Chemistry, vol. 114, no. 3, pp. 898-904, 2009.
    • (2009) Food Chemistry , vol.114 , Issue.3 , pp. 898-904
    • Yang, J.1    Liu, R.H.2
  • 90
    • 80053221096 scopus 로고    scopus 로고
    • Poor oral bioavailability of a promising anticancer agent andrographolide is due to extensive metabolism and efflux by P-glycoprotein
    • L. Ye, T. Wang, L. Tang et al. , "Poor oral bioavailability of a promising anticancer agent andrographolide is due to extensive metabolism and efflux by P-glycoprotein," Journal of Pharmaceutical Sciences, vol. 100, no. 11, pp. 5007-5017, 2011.
    • (2011) Journal of Pharmaceutical Sciences , vol.100 , Issue.11 , pp. 5007-5017
    • Ye, L.1    Wang, T.2    Tang, L.3
  • 92
    • 77955893766 scopus 로고    scopus 로고
    • Diindolylmethane (DIM) spontaneously forms from indole-3-carbinol (I3C) during cell culture experiments
    • H. L. Bradlow and M. A. Zeligs, "Diindolylmethane (DIM) spontaneously forms from indole-3-carbinol (I3C) during cell culture experiments," In Vivo, vol. 24, no. 4, pp. 387-391, 2010.
    • (2010) In Vivo , vol.24 , Issue.4 , pp. 387-391
    • Bradlow, H.L.1    Zeligs, M.A.2
  • 93
    • 33746847720 scopus 로고    scopus 로고
    • Catechol estrogen quinones as initiators of breast and other human cancers: Implications for biomarkers of susceptibility and cancer prevention
    • E. Cavalieri, D. Chakravarti, J. Guttenplan et al. , "Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention," Biochimica et Biophysica Acta, vol. 1766, no. 1, pp. 63-78, 2006.
    • (2006) Biochimica et Biophysica Acta , vol.1766 , Issue.1 , pp. 63-78
    • Cavalieri, E.1    Chakravarti, D.2    Guttenplan, J.3
  • 94
    • 34249099665 scopus 로고    scopus 로고
    • Interplay of genes regulated by estrogen and diindolylmethane in breast cancer cell lines
    • L. Mulvey, A. Chandrasekaran, K. Liu et al. , "Interplay of genes regulated by estrogen and diindolylmethane in breast cancer cell lines," Molecular Medicine, vol. 13, no. 1-2, pp. 69-78, 2007.
    • (2007) Molecular Medicine , vol.13 , Issue.1-2 , pp. 69-78
    • Mulvey, L.1    Chandrasekaran, A.2    Liu, K.3
  • 95
    • 0037367483 scopus 로고    scopus 로고
    • The effect of indole-3-carbinol and sulforaphane on a prostate cancer cell line
    • H. R. Frydoonfar, D. R. McGrath, and A. D. Spigelman, "The effect of indole-3-carbinol and sulforaphane on a prostate cancer cell line," ANZ Journal of Surgery, vol. 73, no. 3, pp. 154-156, 2003.
    • (2003) ANZ Journal of Surgery , vol.73 , Issue.3 , pp. 154-156
    • Frydoonfar, H.R.1    McGrath, D.R.2    Spigelman, A.D.3
  • 96
    • 0036119630 scopus 로고    scopus 로고
    • Development of a multi-organ rat model for evaluating chemopreventive agents: Efficacy of indole-3-carbinol
    • G. Stoner, B. Casto, S. Ralston, B. Roebuck, C. Pereira, and G. Bailey, "Development of a multi-organ rat model for evaluating chemopreventive agents: efficacy of indole-3-carbinol," Carcinogenesis, vol. 23, no. 2, pp. 265-272, 2002.
    • (2002) Carcinogenesis , vol.23 , Issue.2 , pp. 265-272
    • Stoner, G.1    Casto, B.2    Ralston, S.3    Roebuck, B.4    Pereira, C.5    Bailey, G.6
  • 97
  • 98
    • 73949142348 scopus 로고    scopus 로고
    • Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state
    • M. Zakkar, K. Van der Heiden, L. A. Luong et al. , "Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state," Arteriosclerosis, Thrombosis, and Vascular Biology, vol. 29, no. 11, pp. 1851-1857, 2009.
    • (2009) Arteriosclerosis, Thrombosis, and Vascular Biology , vol.29 , Issue.11 , pp. 1851-1857
    • Zakkar, M.1    Van Der Heiden, K.2    Luong, L.A.3
  • 99
    • 84868089323 scopus 로고    scopus 로고
    • Induction of quinone reductase by tamoxifen orDPNprotects againstmammary tumorigenesis
    • N. Krishnamurthy, Y. Hu, S. Siedlak, Y. Q. Doughman, M. Watanabe, and M. M. Montano, "Induction of quinone reductase by tamoxifen orDPNprotects againstmammary tumorigenesis," The FASEB Journal, vol. 26, no. 10, pp. 3993-4002, 2012.
    • (2012) The FASEB Journal , vol.26 , Issue.10 , pp. 3993-4002
    • Krishnamurthy, N.1    Hu, Y.2    Siedlak, S.3    Doughman, Y.Q.4    Watanabe, M.5    Montano, M.M.6
  • 101
    • 77954975984 scopus 로고    scopus 로고
    • Auranofin, a gold(I)-containing antirheumatic compound, activates Keap1/Nrf2 signaling via Rac1/iNOS signal and mitogenactivated protein kinase activation
    • N. -H. Kim, M. -K. Oh, H. J. Park, and I. -S. Kim, "Auranofin, a gold(I)-containing antirheumatic compound, activates Keap1/Nrf2 signaling via Rac1/iNOS signal and mitogenactivated protein kinase activation," Journal of Pharmacological Sciences, vol. 113, no. 3, pp. 246-254, 2010.
    • (2010) Journal of Pharmacological Sciences , vol.113 , Issue.3 , pp. 246-254
    • Kim, N.-H.1    Oh, M.-K.2    Park, H.J.3    Kim, I.-S.4
  • 102
    • 33845953401 scopus 로고    scopus 로고
    • Heme oxygenase-1 protects gastric mucosal cells against non-steroidal antiinflammatory drugs,"The
    • M. Aburaya, K. -I. Tanaka, T. Hoshino et al. , "Heme oxygenase-1 protects gastric mucosal cells against non-steroidal antiinflammatory drugs,"The Journal of Biological Chemistry, vol. 281, no. 44, pp. 33422-33432, 2006.
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.44 , pp. 33422-33432
    • Aburaya, M.1    Tanaka, K.-I.2    Hoshino, T.3
  • 103
    • 79960855656 scopus 로고    scopus 로고
    • Bardoxolone methyl and kidney function in CKD with type 2 diabetes
    • P. E. Pergola, P. Raskin, R. D. Toto et al. , "Bardoxolone methyl and kidney function in CKD with type 2 diabetes," The New England Journal of Medicine, vol. 365, no. 4, pp. 327-336, 2011.
    • (2011) The New England Journal of Medicine , vol.365 , Issue.4 , pp. 327-336
    • Pergola, P.E.1    Raskin, P.2    Toto, R.D.3
  • 104
    • 79953242026 scopus 로고    scopus 로고
    • New synthetic triterpenoids: Potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress
    • M. B. Sporn, K. T. Liby,M. M. Yore, L. Fu, J. M. Lopchuk, and G. W. Gribble, "New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress," Journal of Natural Products, vol. 74, no. 3, pp. 537-545, 2011.
    • (2011) Journal of Natural Products , vol.74 , Issue.3 , pp. 537-545
    • Sporn, M.B.1    Libym. Yore M, K.T.2    Fu, L.3    Lopchuk, J.M.4    Gribble, G.W.5
  • 105
    • 84893855713 scopus 로고    scopus 로고
    • The Nrf2 pathway in the progression of renal disease
    • C. Zoja, A. Benigni, and G. Remuzzi, "The Nrf2 pathway in the progression of renal disease," Nephrology Dialysis Transplantation, vol. 29, supplement 1, pp. i19-i24, 2014.
    • (2014) Nephrology Dialysis Transplantation , vol.29 , pp. i19-i24
    • Zoja, C.1    Benigni, A.2    Remuzzi, G.3
  • 106
    • 23044440041 scopus 로고    scopus 로고
    • Oleanolic acid and ursolic acid: Research perspectives
    • J. Liu, "Oleanolic acid and ursolic acid: research perspectives," Journal of Ethnopharmacology, vol. 100, no. 1-2, pp. 92-94, 2005.
    • (2005) Journal of Ethnopharmacology , vol.100 , Issue.1-2 , pp. 92-94
    • Liu, J.1
  • 107
    • 79955763790 scopus 로고    scopus 로고
    • Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1
    • Q. Q. Wu, Y. Wang, M. Senitko et al. , "Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1," American Journal of Physiology-Renal Physiology, vol. 300, no. 5, pp. 1180-1192, 2011.
    • (2011) American Journal of Physiology-Renal Physiology , vol.300 , Issue.5 , pp. 1180-1192
    • Wu, Q.Q.1    Wang, Y.2    Senitko, M.3
  • 108
    • 84874615691 scopus 로고    scopus 로고
    • Rationale and trial design of bardoxolone methyl evaluation in patients with chronic kidney disease and type 2 diabetes: The occurrence of renal events (BEACON)
    • D. de Zeeuw, T. Akizawa, R. Agarwal et al. , "Rationale and trial design of bardoxolone methyl evaluation in patients with chronic kidney disease and type 2 diabetes: the occurrence of renal events (BEACON)," American Journal of Nephrology, vol. 37, no. 3, pp. 212-222, 2013.
    • (2013) American Journal of Nephrology , vol.37 , Issue.3 , pp. 212-222
    • De Zeeuw, D.1    Akizawa, T.2    Agarwal, R.3
  • 109
  • 111
    • 80755171414 scopus 로고    scopus 로고
    • Antioxidant supplementation during exercise training: Beneficial or detrimental?
    • T. -T. Peternelj and J. S. Coombes, "Antioxidant supplementation during exercise training: beneficial or detrimental?" Sports Medicine, vol. 41, no. 12, pp. 1043-1069, 2011.
    • (2011) Sports Medicine , vol.41 , Issue.12 , pp. 1043-1069
    • Peternelj, T.-T.1    Coombes, J.S.2
  • 112
    • 77649272110 scopus 로고    scopus 로고
    • A systems biology perspective on Nrf2-mediated antioxidant response
    • Q. Zhang, J. Pi, C. G. Woods, and M. E. Andersen, "A systems biology perspective on Nrf2-mediated antioxidant response," Toxicology and Applied Pharmacology, vol. 244, no. 1, pp. 84-97, 2010.
    • (2010) Toxicology and Applied Pharmacology , vol.244 , Issue.1 , pp. 84-97
    • Zhang, Q.1    Pi, J.2    Woods, C.G.3    Andersen, M.E.4
  • 113
    • 84855451533 scopus 로고    scopus 로고
    • Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium
    • V. R. Muthusamy, S. Kannan, K. Sadhaasivam et al. , "Acute exercise stress activates Nrf2/ARE signaling and promotes antioxidant mechanisms in the myocardium," Free Radical Biology and Medicine, vol. 52, no. 2, pp. 366-376, 2012.
    • (2012) Free Radical Biology and Medicine , vol.52 , Issue.2 , pp. 366-376
    • Muthusamy, V.R.1    Kannan, S.2    Sadhaasivam, K.3
  • 114
    • 84896079928 scopus 로고    scopus 로고
    • Physical activity and prostate gene expression in men with low-risk prostate cancer
    • M. J. M. Magbanua, E. L. Richman, E. V. Sosa et al. , "Physical activity and prostate gene expression in men with low-risk prostate cancer," Cancer Causes and Control, vol. 25, no. 4, pp. 515-523, 2014.
    • (2014) Cancer Causes and Control , vol.25 , Issue.4 , pp. 515-523
    • Magbanua, M.J.M.1    Richman, E.L.2    Sosa, E.V.3
  • 115
    • 84884864669 scopus 로고    scopus 로고
    • The aryl hydrocarbon receptor interacts with nuclear factor erythroid 2-related factor 2 to mediate induction of NAD(P)H:quinoneoxidoreductase 1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • L. Wang, X. He, G. D. Szklarz, Y. Bi, Y. Rojanasakul, and Q. Ma, "The aryl hydrocarbon receptor interacts with nuclear factor erythroid 2-related factor 2 to mediate induction of NAD(P)H:quinoneoxidoreductase 1 by 2,3,7,8-tetrachlorodibenzo-p-dioxin," Archives of Biochemistry and Biophysics, vol. 537, no. 1, pp. 31-38, 2013.
    • (2013) Archives of Biochemistry and Biophysics , vol.537 , Issue.1 , pp. 31-38
    • Wang, L.1    He, X.2    Szklarz, G.D.3    Bi, Y.4    Rojanasakul, Y.5    Ma, Q.6
  • 116
    • 33644833039 scopus 로고    scopus 로고
    • Relative imbalances in the expression of estrogen-metabolizing enzymes in the breast tissue of women with breast carcinoma
    • S. Singh, D. Chakravarti, J. A. Edney et al. , "Relative imbalances in the expression of estrogen-metabolizing enzymes in the breast tissue of women with breast carcinoma," Oncology Reports, vol. 14, no. 4, pp. 1091-1096, 2005.
    • (2005) Oncology Reports , vol.14 , Issue.4 , pp. 1091-1096
    • Singh, S.1    Chakravarti, D.2    Edney, J.A.3
  • 117
    • 2142655894 scopus 로고    scopus 로고
    • NAD(P)H:quinone oxidoreductase 1: Role as a superoxide scavenger
    • D. Siegel, D. L. Gustafson, D. L. Dehn et al. , "NAD(P)H:quinone oxidoreductase 1: role as a superoxide scavenger," Molecular Pharmacology, vol. 65, no. 5, pp. 1238-1247, 2004.
    • (2004) Molecular Pharmacology , vol.65 , Issue.5 , pp. 1238-1247
    • Siegel, D.1    Gustafson, D.L.2    Dehn, D.L.3
  • 118
    • 84883741204 scopus 로고    scopus 로고
    • The NQO1 polymorphism C609T (Pro187Ser) and cancer susceptibility: A comprehensive metaanalysis
    • B. Lajin and A. Alachkar, "The NQO1 polymorphism C609T (Pro187Ser) and cancer susceptibility: a comprehensive metaanalysis," British Journal of Cancer, vol. 109, no. 5, pp. 1325-1337, 2013.
    • (2013) British Journal of Cancer , vol.109 , Issue.5 , pp. 1325-1337
    • Lajin, B.1    Alachkar, A.2
  • 119
    • 84938865951 scopus 로고    scopus 로고
    • Protective effects of Brassica oleracea sprouts extract toward renal damage in highsalt-fed SHRSP: Role of AMPK/PPAR/UCP2 axis
    • S. Rubattu, S. Di Castro,M. Cotugno et al. , "Protective effects of Brassica oleracea sprouts extract toward renal damage in highsalt-fed SHRSP: role of AMPK/PPAR/UCP2 axis," Journal of Hypertension, vol. 33, no. 7, pp. 1465-1479, 2015.
    • (2015) Journal of Hypertension , vol.33 , Issue.7 , pp. 1465-1479
    • Rubattu, S.1    Di Castro, M.2    Cotugno, S.3
  • 120
    • 84902554414 scopus 로고    scopus 로고
    • Vitroin vivo extrapolation (IVIVE) for predicting human intestinal absorption and first-pass elimination of drugs: Principles and applications
    • H. -J. Cho, J. -E. Kim, D. -D. Kim, and I. -S. Yoon, "In vitroin vivo extrapolation (IVIVE) for predicting human intestinal absorption and first-pass elimination of drugs: principles and applications," Drug Development and Industrial Pharmacy, vol. 40, no. 8, pp. 989-998, 2014.
    • (2014) Drug Development and Industrial Pharmacy , vol.40 , Issue.8 , pp. 989-998
    • Cho, H.-J.1    Kim, J.-E.2    Kim, D.-D.3    Yoon, I.-S.4
  • 121
    • 35348860160 scopus 로고    scopus 로고
    • Modeling gastrointestinal drug absorption requires more in vivo biopharmaceutical data: Experience from in vivo dissolution and permeability studies in humans
    • H. Lennernäs, "Modeling gastrointestinal drug absorption requires more in vivo biopharmaceutical data: experience from in vivo dissolution and permeability studies in humans," Current Drug Metabolism, vol. 8, no. 7, pp. 645-657, 2007.
    • (2007) Current Drug Metabolism , vol.8 , Issue.7 , pp. 645-657
    • Lennernäs, H.1
  • 122
    • 37549016731 scopus 로고    scopus 로고
    • Commentary: Bioavailability of flavonoids and polyphenols: Call to arms
    • M. Hu, "Commentary: bioavailability of flavonoids and polyphenols: call to arms," Molecular Pharmaceutics, vol. 4, no. 6, pp. 803-806, 2007.
    • (2007) Molecular Pharmaceutics , vol.4 , Issue.6 , pp. 803-806
    • Hu, M.1
  • 124
    • 38949204895 scopus 로고    scopus 로고
    • Absolute bioavailability and dose-dependent pharmacokinetic behaviour of dietary doses of the chemopreventive isothiocyanate sulforaphane in rat
    • N. Hanlon, N. Coldham, A. Gielbert et al. , "Absolute bioavailability and dose-dependent pharmacokinetic behaviour of dietary doses of the chemopreventive isothiocyanate sulforaphane in rat," British Journal of Nutrition, vol. 99, no. 3, pp. 559-564, 2008.
    • (2008) British Journal of Nutrition , vol.99 , Issue.3 , pp. 559-564
    • Hanlon, N.1    Coldham, N.2    Gielbert, A.3
  • 125
    • 38749131263 scopus 로고    scopus 로고
    • Effects of dietary polyphenols on gene expression in human vascular endothelial cells
    • S. K. Nicholson, G. A. Tucker, and J. M. Brameld, "Effects of dietary polyphenols on gene expression in human vascular endothelial cells," Proceedings of the Nutrition Society, vol. 67, no. 1, pp. 42-47, 2008.
    • (2008) Proceedings of the Nutrition Society , vol.67 , Issue.1 , pp. 42-47
    • Nicholson, S.K.1    Tucker, G.A.2    Brameld, J.M.3
  • 129
    • 84856401398 scopus 로고    scopus 로고
    • Reassessing bioavailability of silymarin
    • S. Javed, K. Kohli, and M. Ali, "Reassessing bioavailability of silymarin," Alternative Medicine Review, vol. 16, no. 3, pp. 239-249, 2011.
    • (2011) Alternative Medicine Review , vol.16 , Issue.3 , pp. 239-249
    • Javed, S.1    Kohli, K.2    Ali, M.3
  • 131
    • 9744222928 scopus 로고    scopus 로고
    • Potential synergy of phytochemicals in cancer prevention:mechanismof action
    • R. H. Liu, "Potential synergy of phytochemicals in cancer prevention:mechanismof action," Journal of Nutrition, vol. 134, no. 12, supplement, pp. 3479S-3485S, 2004.
    • (2004) Journal of Nutrition , vol.134 , Issue.12 , pp. 3479S-3485S
    • Liu, R.H.1
  • 132
    • 0035584140 scopus 로고    scopus 로고
    • The stomach as a bioreactor: Dietary lipid peroxidation in the gastric fluid and the effects of plantderived antioxidants
    • J. Kanner and T. Lapidot, "The stomach as a bioreactor: dietary lipid peroxidation in the gastric fluid and the effects of plantderived antioxidants," Free Radical Biology and Medicine, vol. 31, no. 11, pp. 1388-1395, 2001.
    • (2001) Free Radical Biology and Medicine , vol.31 , Issue.11 , pp. 1388-1395
    • Kanner, J.1    Lapidot, T.2
  • 133
    • 77956634425 scopus 로고    scopus 로고
    • Hormesis and synergy: Pathways and mechanisms of quercetin in cancer prevention and management
    • A. J. Vargas and R. Burd, "Hormesis and synergy: pathways and mechanisms of quercetin in cancer prevention and management," Nutrition Reviews, vol. 68, no. 7, pp. 418-428, 2010.
    • (2010) Nutrition Reviews , vol.68 , Issue.7 , pp. 418-428
    • Vargas, A.J.1    Burd, R.2
  • 134
  • 135
    • 27744563096 scopus 로고    scopus 로고
    • Essential requirement of reduced glutathione (GSH) for the anti-oxidant effect of the flavonoid quercetin
    • R. Ferraresi, L. Troiano, E. Roat et al. , "Essential requirement of reduced glutathione (GSH) for the anti-oxidant effect of the flavonoid quercetin," Free Radical Research, vol. 39, no. 11, pp. 1249-1258, 2005.
    • (2005) Free Radical Research , vol.39 , Issue.11 , pp. 1249-1258
    • Ferraresi, R.1    Troiano, L.2    Roat, E.3
  • 136
    • 5744248613 scopus 로고    scopus 로고
    • Phytochemicals inhibit catechol-O-methyltransferase activity in cytosolic fractions fromhealthy human mammary tissues: Implications for catechol estrogeninduced DNA damage
    • M. B. M. van Duursen, J. T. Sanderson, P. C. de Jong, M. Kraaij, and M. van den Berg, "Phytochemicals inhibit catechol-O-methyltransferase activity in cytosolic fractions fromhealthy human mammary tissues: implications for catechol estrogeninduced DNA damage," Toxicological Sciences, vol. 81, no. 2, pp. 316-324, 2004.
    • (2004) Toxicological Sciences , vol.81 , Issue.2 , pp. 316-324
    • Van Duursen, M.B.M.1    Sanderson, J.T.2    De Jong, P.C.3    Den Van Berg, M.4    Kraaij, M.5
  • 138
    • 84874105071 scopus 로고    scopus 로고
    • Curcumin in inflammatory diseases
    • A. Shehzad, G. Rehman, and Y. S. Lee, "Curcumin in inflammatory diseases," Bio Factors, vol. 39, no. 1, pp. 69-77, 2013.
    • (2013) Bio Factors , vol.39 , Issue.1 , pp. 69-77
    • Shehzad, A.1    Rehman, G.2    Lee, Y.S.3
  • 139
    • 80051484401 scopus 로고    scopus 로고
    • Curcumin modulates nuclear factor κb (nf-κB)-mediated inflammation in human tenocytes in vitro: Role of the phosphatidylinositol 3-kinase/Akt pathway
    • C. Buhrmann, A. Mobasheri, F. Busch et al. , "Curcumin modulates nuclear factor κB (nf-κB)-mediated inflammation in human tenocytes in vitro: role of the phosphatidylinositol 3-kinase/Akt pathway," Journal of Biological Chemistry, vol. 286, no. 32, pp. 28556-28566, 2011.
    • (2011) Journal of Biological Chemistry , vol.286 , Issue.32 , pp. 28556-28566
    • Buhrmann, C.1    Mobasheri, A.2    Busch, F.3
  • 140
    • 6044276740 scopus 로고    scopus 로고
    • Phase i clinical trial of oral curcumin: Biomarkers of systemic activity and compliance
    • R. A. Sharma, S. A. Euden, S. L. Platton et al. , "Phase I clinical trial of oral curcumin: biomarkers of systemic activity and compliance," Clinical Cancer Research, vol. 10, no. 20, pp. 6847-6854, 2004.
    • (2004) Clinical Cancer Research , vol.10 , Issue.20 , pp. 6847-6854
    • Sharma, R.A.1    Euden, S.A.2    Platton, S.L.3
  • 141
    • 34548438445 scopus 로고    scopus 로고
    • Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals
    • L. M. Howells, E. P. Moiseeva, C. P. Neal et al. , "Predicting the physiological relevance of in vitro cancer preventive activities of phytochemicals," Acta Pharmacologica Sinica, vol. 28, no. 9, pp. 1274-1304, 2007.
    • (2007) Acta Pharmacologica Sinica , vol.28 , Issue.9 , pp. 1274-1304
    • Howells, L.M.1    Moiseeva, E.P.2    Neal, C.P.3
  • 142
    • 55949117806 scopus 로고    scopus 로고
    • Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases
    • B. B. Aggarwal and K. B. Harikumar, "Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic diseases," International Journal of Biochemistry and Cell Biology, vol. 41, no. 1, pp. 40-59, 2009.
    • (2009) International Journal of Biochemistry and Cell Biology , vol.41 , Issue.1 , pp. 40-59
    • Aggarwal, B.B.1    Harikumar, K.B.2
  • 143
    • 84881361511 scopus 로고    scopus 로고
    • Curcumin: A boon to colonic diseases
    • R. Sareen, N. Jain, and V. Pandit, "Curcumin: a boon to colonic diseases," Current Drug Targets, vol. 14, no. 10, pp. 1210-1218, 2013.
    • (2013) Current Drug Targets , vol.14 , Issue.10 , pp. 1210-1218
    • Sareen, R.1    Jain, N.2    Pandit, V.3
  • 144
    • 84879628500 scopus 로고    scopus 로고
    • Turmeric (curcumin) remedies gastroprotective action
    • S. K. Yadav, A. K. Sah, R. K. Jha, P. Sah, and D. K. Shah, "Turmeric (curcumin) remedies gastroprotective action," Pharmacognosy Reviews, vol. 7, no. 13, pp. 42-46, 2013.
    • (2013) Pharmacognosy Reviews , vol.7 , Issue.13 , pp. 42-46
    • Yadav, S.K.1    Sah, A.K.2    Jha, R.K.3    Sah, P.4    Shah, D.K.5
  • 145
    • 4644332608 scopus 로고    scopus 로고
    • Detection of curcumin and itsmetabolites in hepatic tissue and portal blood of patients following oral administration
    • G. Garcea, D. J. L. Jones, R. Singh et al. , "Detection of curcumin and itsmetabolites in hepatic tissue and portal blood of patients following oral administration," British Journal of Cancer, vol. 90, no. 5, pp. 1011-1015, 2004.
    • (2004) British Journal of Cancer , vol.90 , Issue.5 , pp. 1011-1015
    • Garcea, G.1    Jones, D.J.L.2    Singh, R.3
  • 146
    • 58149084882 scopus 로고    scopus 로고
    • A pilot cross-over study to evaluate human oral bioavailability of BCM-95CG (Biocurcumax), a novel bioenhanced preparation of curcumin
    • B. Antony, B. Merina, V. S. Iyer, N. Judy, K. Lennertz, and S. Joyal, "A pilot cross-over study to evaluate human oral bioavailability of BCM-95CG (Biocurcumax), a novel bioenhanced preparation of curcumin," Indian Journal of Pharmaceutical Sciences, vol. 70, no. 4, pp. 445-449, 2008.
    • (2008) Indian Journal of Pharmaceutical Sciences , vol.70 , Issue.4 , pp. 445-449
    • Antony, B.1    Merina, B.2    Iyer, V.S.3    Judy, N.4    Lennertz, K.5    Joyal, S.6
  • 148
    • 33751072349 scopus 로고    scopus 로고
    • Resveratrol improves health and survival of mice on a high-calorie diet
    • J. A. Baur, K. J. Pearson, N. L. Price et al. , "Resveratrol improves health and survival of mice on a high-calorie diet," Nature, vol. 444, no. 7117, pp. 337-342, 2006.
    • (2006) Nature , vol.444 , Issue.7117 , pp. 337-342
    • Baur, J.A.1    Pearson, K.J.2    Price, N.L.3
  • 149
    • 48349144852 scopus 로고    scopus 로고
    • Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span
    • K. J. Pearson, J. A. Baur, K. N. Lewis et al. , "Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span," Cell Metabolism, vol. 8, no. 2, pp. 157-168, 2008.
    • (2008) Cell Metabolism , vol.8 , Issue.2 , pp. 157-168
    • Pearson, J.A.1    Lewis, N.B.K.2
  • 150
    • 79953043473 scopus 로고    scopus 로고
    • Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy
    • article e10
    • E. Morselli, M. C. Maiuri, M. Markaki et al. , "Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy," Cell Death and Disease, vol. 1, no. 1, article e10, 2010.
    • (2010) Cell Death and Disease , vol.1 , Issue.1
    • Morselli, E.1    Maiuri, M.C.2    Markaki, M.3
  • 151
    • 79961047423 scopus 로고    scopus 로고
    • Resveratrol and health-A comprehensive review of human clinical trials
    • J. M. Smoliga, J. A. Baur, and H. A. Hausenblas, "Resveratrol and health-a comprehensive review of human clinical trials," Molecular Nutrition and Food Research, vol. 55, no. 8, pp. 1129-1141, 2011.
    • (2011) Molecular Nutrition and Food Research , vol.55 , Issue.8 , pp. 1129-1141
    • Smoliga, J.M.1    Baur, J.A.2    Hausenblas, H.A.3
  • 153
    • 9444296057 scopus 로고    scopus 로고
    • High absorption but very low bioavailability of oral resveratrol in humans
    • T. Walle, F. Hsieh,M. H. DeLegge, J. E. Oatis Jr. , and U. K. Walle, "High absorption but very low bioavailability of oral resveratrol in humans,"DrugMetabolismandDisposition, vol. 32,no. 12,pp. 1377-1382, 2004.
    • (2004) DrugMetabolismandDisposition , vol.32 , Issue.12 , pp. 1377-1382
    • Walle, T.1    Hsieh, F.2    DeLegge, M.3    Oatis, J.E.4    Walle, U.K.5
  • 154
    • 84918791665 scopus 로고    scopus 로고
    • Resveratrol does not benefit patients with nonalcoholic fatty liver disease
    • V. S. Chachay, G. A. Macdonald, J. H. Martin et al. , "Resveratrol does not benefit patients with nonalcoholic fatty liver disease," Clinical Gastroenterology and Hepatology, vol. 12, no. 12, pp. 2092-2103, 2014.
    • (2014) Clinical Gastroenterology and Hepatology , vol.12 , Issue.12 , pp. 2092-2103
    • Chachay, V.S.1    Macdonald, G.A.2    Martin, J.H.3
  • 155
    • 79959261445 scopus 로고    scopus 로고
    • What is new for an old molecule systematic review and recommendations on the use of resveratrol
    • Article ID e19881
    • O. Vang, N. Ahmad, C. A. Baile et al. , "What is new for an old molecule? systematic review and recommendations on the use of resveratrol," PLoS ONE, vol. 6, no. 6,Article ID e19881, 2011.
    • (2011) PLoS ONE , vol.6 , Issue.6
    • Vang, O.1    Ahmad, N.2    Baile, C.A.3
  • 156
    • 33846519345 scopus 로고    scopus 로고
    • Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine
    • S. C. Pradhan and C. Girish, "Hepatoprotective herbal drug, silymarin from experimental pharmacology to clinical medicine," Indian Journal of Medical Research, vol. 124, no. 5, pp. 491-504, 2006.
    • (2006) Indian Journal of Medical Research , vol.124 , Issue.5 , pp. 491-504
    • Pradhan, S.C.1    Girish, C.2
  • 157
    • 77956852506 scopus 로고    scopus 로고
    • Milk thistle in liver diseases: Past, present, future
    • L. Abenavoli, R. Capasso, N. Milic, and F. Capasso, "Milk thistle in liver diseases: past, present, future," Phytotherapy Research, vol. 24, no. 10, pp. 1423-1432, 2010.
    • (2010) Phytotherapy Research , vol.24 , Issue.10 , pp. 1423-1432
    • Abenavoli, L.1    Capasso, R.2    Milic, N.3    Capasso, F.4
  • 158
    • 34547795788 scopus 로고    scopus 로고
    • Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast
    • B. S. Cornblatt, L. Ye, A. T. Dinkova-Kostova et al. , "Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast," Carcinogenesis, vol. 28, no. 7, pp. 1485-1490, 2007.
    • (2007) Carcinogenesis , vol.28 , Issue.7 , pp. 1485-1490
    • Cornblatt, B.S.1    Ye, L.2    Dinkova-Kostova, A.T.3
  • 159
    • 0036135910 scopus 로고    scopus 로고
    • Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: Pharmacokinetics of broccoli sprout isothiocyanates in humans
    • L. Ye, A. T. Dinkova-Kostova, K. L. Wade, Y. Zhang, T. A. Shapiro, and P. Talalay, "Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: pharmacokinetics of broccoli sprout isothiocyanates in humans," Clinica Chimica Acta, vol. 316, no. 1-2, pp. 43-53, 2002.
    • (2002) Clinica Chimica Acta , vol.316 , Issue.1-2 , pp. 43-53
    • Ye, L.1    Dinkova-Kostova, A.T.2    Wade, K.L.3    Zhang, Y.4    Shapiro, T.A.5    Talalay, P.6
  • 160
    • 59249103720 scopus 로고    scopus 로고
    • Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway
    • M. A. Riedl, A. Saxon, andD. Diaz-Sanchez, "Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway," Clinical Immunology, vol. 130, no. 3, pp. 244-251, 2009.
    • (2009) Clinical Immunology , vol.130 , Issue.3 , pp. 244-251
    • Riedl, M.A.1    Saxon, D.2    Diaz-Sanchez, A.3
  • 161
    • 84861913629 scopus 로고    scopus 로고
    • Protection of humans by plant glucosinolates: Efficiency of conversion of glucosinolates to isothiocyanates by the gastrointestinal microflora
    • J. W. Fahey, S. L. Wehage, W. D. Holtzclaw et al. , "Protection of humans by plant glucosinolates: efficiency of conversion of glucosinolates to isothiocyanates by the gastrointestinal microflora," Cancer Prevention Research, vol. 5, no. 4, pp. 603-611, 2012.
    • (2012) Cancer Prevention Research , vol.5 , Issue.4 , pp. 603-611
    • Fahey, J.W.1    Wehage, S.L.2    Holtzclaw, W.D.3
  • 162
    • 34447618972 scopus 로고    scopus 로고
    • Influence of cabbage processing methods and prebiotic manipulationof colonic microflora on glucosinolate breakdown in man
    • Z. Fuller, P. Louis, A. Mihajlovski, V. Rungapamestry, B. Ratcliffe, and A. J. Duncan, "Influence of cabbage processing methods and prebiotic manipulationof colonic microflora on glucosinolate breakdown in man," British Journal of Nutrition, vol. 98, no. 2, pp. 364-372, 2007.
    • (2007) British Journal of Nutrition , vol.98 , Issue.2 , pp. 364-372
    • Fuller, Z.1    Louis, P.2    Mihajlovski, A.3    Rungapamestry, V.4    Ratcliffe, B.5    Duncan, A.J.6
  • 163
    • 28644450910 scopus 로고    scopus 로고
    • Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo Township, Qidong, People's Republic of China
    • T. W. Kensler, J. -G. Chen, P. A. Egner et al. , "Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo Township, Qidong, People's Republic of China," Cancer Epidemiology Biomarkers and Prevention, vol. 14, no. 11, part 1, pp. 2605-2613, 2005.
    • (2005) Cancer Epidemiology Biomarkers and Prevention , vol.14 , Issue.11 , pp. 2605-2613
    • Kensler, T.W.1    Chen, J.-G.2    Egner, P.A.3
  • 164
    • 2942614968 scopus 로고    scopus 로고
    • Heating decreases epithiospecifier protein activity and increases sulforaphane formation in broccoli
    • N. V. Matusheski, J. A. Juvik, and E. H. Jeffery, "Heating decreases epithiospecifier protein activity and increases sulforaphane formation in broccoli," Phytochemistry, vol. 65, no. 9, pp. 1273-1281, 2004.
    • (2004) Phytochemistry , vol.65 , Issue.9 , pp. 1273-1281
    • Matusheski, N.V.1    Juvik, J.A.2    Jeffery, E.H.3
  • 165
    • 1042278894 scopus 로고    scopus 로고
    • In vitro digestion of sinigrin and glucotropaeolin by single strains of Bifidobacterium and identification of the digestive products
    • D. -L. Cheng, K. Hashimoto, and Y. Uda, "In vitro digestion of sinigrin and glucotropaeolin by single strains of Bifidobacterium and identification of the digestive products," Food and Chemical Toxicology, vol. 42, no. 3, pp. 351-357, 2004.
    • (2004) Food and Chemical Toxicology , vol.42 , Issue.3 , pp. 351-357
    • Cheng, D.-L.1    Hashimoto, K.2    Uda, Y.3
  • 166
    • 0034434321 scopus 로고    scopus 로고
    • Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh broccoli
    • C. C. Conaway, S. M. Getahun, L. L. Liebes et al. , "Disposition of glucosinolates and sulforaphane in humans after ingestion of steamed and fresh broccoli," Nutrition and Cancer, vol. 38, no. 2, pp. 168-178, 2000.
    • (2000) Nutrition and Cancer , vol.38 , Issue.2 , pp. 168-178
    • Conaway, C.C.1    Getahun, S.M.2    Liebes, L.L.3
  • 167
    • 80054979844 scopus 로고    scopus 로고
    • Bioavailability and interconversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a crossover study design
    • J. D. Clarke, A. Hsu, K. Riedl et al. , "Bioavailability and interconversion of sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a crossover study design," Pharmacological Research, vol. 64, no. 5, pp. 456-463, 2011.
    • (2011) Pharmacological Research , vol.64 , Issue.5 , pp. 456-463
    • Clarke, J.D.1    Hsu, A.2    Riedl, K.3
  • 168
    • 84887612717 scopus 로고    scopus 로고
    • Sulforaphane: Translational research from laboratory bench to clinic
    • C. A. Houghton, R. G. Fassett, and J. S. Coombes, "Sulforaphane: translational research from laboratory bench to clinic," Nutrition Reviews, vol. 71, no. 11, pp. 709-726, 2013.
    • (2013) Nutrition Reviews , vol.71 , Issue.11 , pp. 709-726
    • Houghton, C.A.1    Fassett, R.G.2    Coombes, J.S.3
  • 169
    • 84875056446 scopus 로고    scopus 로고
    • Microarray and pathway analysis highlight Nrf2/ARE-mediated expression profiling by polyphenolic myricetin
    • S. Qin, J. Chen, S. Tanigawa, and D. -X. Hou, "Microarray and pathway analysis highlight Nrf2/ARE-mediated expression profiling by polyphenolic myricetin," Molecular Nutrition and Food Research, vol. 57, no. 3, pp. 435-446, 2013.
    • (2013) Molecular Nutrition and Food Research , vol.57 , Issue.3 , pp. 435-446
    • Qin, S.1    Chen, J.2    Tanigawa, S.3    Hou, D.-X.4


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