NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector

Archives of Biochemistry and Biophysics

Volumn 501, Issue 1, 2010, Pages 116-123

  Dinkova Kostova, Albena T ^a,b   Talalay, Paul ^b  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Antioxidant response element (ARE); Benzene toxicity; Estrogen quinone; Keap1; Microtubule stability; Nrf2; Oxidative stress; P53; Proteasomal degradation

Indexed keywords

KELCH LIKE ECH ASSOCIATED PROTEIN 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE DEHYDROGENASE 1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ANTIOXIDANT; ESTROGEN; KEAP1 PROTEIN, HUMAN; NQO1 PROTEIN, HUMAN; PROTEASOME; PROTEIN BINDING; PROTEIN P53; QUINONE DERIVATIVE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SIGNAL PEPTIDE; TP53 PROTEIN, HUMAN;

ANTIOXIDANT RESPONSIVE ELEMENT; CELL PROTECTION; ENZYME ACTIVITY; HUMAN; NEUROPROTECTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN DEGRADATION; REVIEW; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOLOGICAL MODEL; GENE INACTIVATION; GENE SILENCING; GENETIC POLYMORPHISM; GENETICS; METABOLISM; PROTEIN STABILITY; SIGNAL TRANSDUCTION; TOXICITY;

ANIMALS; ANTIOXIDANTS; ESTROGENS; GENE KNOCKDOWN TECHNIQUES; GENE KNOCKOUT TECHNIQUES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, BIOLOGICAL; NAD(P)H DEHYDROGENASE (QUINONE); OXIDATIVE STRESS; POLYMORPHISM, GENETIC; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEIN STABILITY; QUINONES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 77956171147     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2010.03.019     Document Type: Review

References (113)

1. Harman D., Amer J. Aging Assoc. 2000, 23:25-31.
2. S. Moloughney, Neutraceutical World, 2010. Available from http://neutraceuticalworld.com/contents/view/14063.
3. Fridovich I. Annu. Rev. Biochem. 1995, 64:97-112.
4. Sies H. Oxidative Stress II. Oxidants and Antioxidants 1991, Academic Press, London.
5. Lane N. Oxygen The Molecule that made the World 2002, Oxford University Press, Oxford.
6. Halliwell B., Gutteridge J.M.C. Free Radicals in Biology and Medicine 2007, Oxford University Press. fourth ed.
7. Dinkova-Kostova A.T., Cheah J., Samouilov A., Zweier J.L., Bozak R.E., Hicks R.J., Talalay P. Med. Chem. 2007, 3:261-268.
8. Dinkova-Kostova A.T., Talalay P. Mol. Nutr. Food Res. 2008, 52(Suppl. 1):S128-S138.
9. Talalay P. Biofactors 2000, 12:5-11.
10. Kensler T.W., Wakabayashi N., Biswal S. Annu. Rev. Pharmacol. Toxicol. 2007, 47:89-116.
11. Holtzclaw W.D., Dinkova-Kostova A.T., Talalay P. Adv. Enzyme Regul. 2004, 44:335-367.
12. Dinkova-Kostova A.T., Holtzclaw W.D., Kensler T.W. Chem. Res. Toxicol. 2005, 18:1779-1791.
13. Ross D. Drug Metab. Rev. 2004, 36:639-654.
14. Ernster L., Navazio F. Acta Chem. Scand. 1958, 12:595.
15. Märki F., Martius C. Biochem. Z. 1960, 333:111-135.
16. Iyanagi T., Yamazaki I. Biochim. Biophys. Acta 1970, 216:288-294.
17. Faig M., Bianchet M.A., Talalay P., Chen S., Winski S., Ross D., Amzel L.M. Proc. Natl. Acad. Sci. USA 2000, 97:3177-3182.
18. Bianchet M.A., Faig M., Amzel L.M. Methods Enzymol. 2004, 382:144-174.
19. Deller S., Macheroux P., Sollner S. Cell. Mol. Life Sci. 2008, 65:141-160.
20. Williams-Ashman H.G., Huggins C. Med. Exp. Int. J. Exp. Med. 1961, 4:223-226.
21. Huggins C. Experimental Leukemia and Mammary Cancer: Induction, Prevention, Cure 1979, The University of Chicago Press, Chicago.
22. Prochaska H.J., Santamaria A.B. Anal. Biochem. 1988, 169:328-336.
23. Prochaska H.J., Santamaria A.B., Talalay P. Proc. Natl. Acad. Sci. USA 1992, 89:2394-2398.
24. Fahey J.W., Dinkova-Kostova A.T., Stephenson K.K., Talalay P. Methods Enzymol. 2004, 382:243-258.
25. Zhang Y., Talalay P., Cho C.G., Posner G.H. Proc. Natl. Acad. Sci. USA 1992, 89:2399-2403.
26. Zhang Y., Tang L. Acta Pharmacol. Sin. 2007, 28:1343-1354.
27. Dinkova-Kostova A.T., Fahey J.W., Talalay P. Methods Enzymol. 2004, 382:423-448.
28. Pearson K.J., Lewis K.N., Price N.L., Chang J.W., Perez E., Cascajo M.V., Tamashiro K.L., Poosala S., Csiszar A., Ungvari Z., Kensler T.W., Yamamoto M., Egan J.M., Longo D.L., Ingram D.K., Navas P., de Cabo R. Proc. Natl. Acad. Sci. USA 2008, 105:2325-2330.
29. Motohashi H., Yamamoto M. Trends Mol. Med. 2004, 10:549-557.
30. Nguyen T., Nioi P., Pickett C.B. J. Biol. Chem. 2009, 284:13291-13295.
31. Hayes J.D., McMahon M. Trends Biochem. Sci. 2009, 34:176-188.
32. Nguyen T., Sherratt P.J., Pickett C.B. Annu. Rev. Pharmacol. Toxicol. 2003, 43:233-260.
33. Nioi P., McMahon M., Itoh K., Yamamoto M., Hayes J.D. Biochem. J. 2003, 374:337-348.
34. Moi P., Chan K., Asunis I., Cao A., Kan Y.W. Proc. Natl. Acad. Sci. USA 1994, 91:9926-9930.
35. Itoh K., Chiba T., Takahashi S., Ishii T., Igarashi K., Katoh Y., Oyake T., Hayashi N., Satoh K., Hatayama I., Yamamoto M., Nabeshima Y. Biochem. Biophys. Res. Commun. 1997, 236:313-322.
36. Itoh K., Wakabayashi N., Katoh Y., Ishii T., Igarashi K., Engel J.D., Yamamoto M. Genes Dev. 1999, 13:76-86.
37. Itoh K., Wakabayashi N., Katoh Y., Ishii T., O'Connor T., Yamamoto M. Genes Cells 2003, 8:379-391.
38. McMahon M., Itoh K., Yamamoto M., Hayes J.D. J. Biol. Chem. 2003, 278:21592-21600.
39. Zhang D.D., Lo S.C., Cross J.V., Templeton D.J., Hannink M. Mol. Cell. Biol. 2004, 24:10941-10953.
40. Cullinan S.B., Gordan J.D., Jin J., Harper J.W., Diehl J.A. Mol. Cell. Biol. 2004, 24:8477-8486.
41. Kobayashi A., Kang M.I., Okawa H., Ohtsuji M., Zenke Y., Chiba T., Igarashi K., Yamamoto M. Mol. Cell. Biol. 2004, 24:7130-7139.
42. Dinkova-Kostova A.T., Holtzclaw W.D., Cole R.N., Itoh K., Wakabayashi N., Katoh Y., Yamamoto M., Talalay P. Proc. Natl. Acad. Sci. USA 2002, 99:11908-11913.
43. Farmer E.E., Davoine C. Curr. Opin. Plant Biol. 2007, 10:380-386.
44. Benson A.M., Hunkeler M.J., Talalay P. Proc. Natl. Acad. Sci. USA 1980, 77:5216-5220.
45. Suh J.H., Shenvi S.V., Dixon B.M., Liu H., Jaiswal A.K., Liu R.M., Hagen T.M. Proc. Natl. Acad. Sci. USA 2004, 101:3381-3386.
46. Wefers H., Komai T., Talalay P., Sies H. FEBS Lett. 1984, 169:63-66.
47. Prochaska H.J., Talalay P., Sies H. J. Biol. Chem. 1987, 262:1931-1934.
48. Siegel D., Gustafson D.L., Dehn D.L., Han J.Y., Boonchoong P., Berliner L.J., Ross D. Mol. Pharmacol. 2004, 65:1238-1247.
49. Zhu H., Jia Z., Mahaney J.E., Ross D., Misra H.P., Trush M.A., Li Y. Cardiovasc. Toxicol. 2007, 7:202-211.
50. D. Ross, H. Zhou, Chem. Biol. Interact., in press, doi:10.1016/j.cbi.2009.11.017.
51. Lan Q., Zhang L., Li G., Vermeulen R., Weinberg R.S., Dosemeci M., Rappaport S.M., Shen M., Alter B.P., Wu Y., Kopp W., Waidyanatha S., Rabkin C., Guo W., Chanock S., Hayes R.B., Linet M., Kim S., Yin S., Rothman N., Smith M.T. Science 2004, 306:1774-1776.
52. Ross D., Kepa J.K., Winski S.L., Beall H.D., Anwar A., Siegel D. Chem. Biol. Interact. 2000, 129:77-97.
53. Ross D., Siegel D. Methods Enzymol. 2004, 382:115-144.
54. Ross D. Chem. Biol. Interact. 2005, 153-154:137-146.
55. Siegel D., Anwar A., Winski S.L., Kepa J.K., Zolman K.L., Ross D. Mol. Pharmacol. 2001, 59:263-268.
56. Edwards Y.H., Potter J., Hopkinson D.A. Biochem. J. 1980, 187:429-436.
57. Smith M.T. Proc. Natl. Acad. Sci. USA 1999, 96:7624-7626.
58. Rothman N., Smith M.T., Hayes R.B., Traver R.D., Hoener B., Campleman S., Li G.L., Dosemeci M., Linet M., Zhang L., Xi L., Wacholder S., Lu W., Meyer K.B., Titenko-Holland N., Stewart J.T., Yin S., Ross D. Cancer Res. 1997, 57:2839-2842.
59. Moran J.L., Siegel D., Ross D. Proc. Natl. Acad. Sci. USA 1999, 96:8150-8155.
60. Bauer A.K., Faiola B., Abernethy D.J., Marchan R., Pluta L.J., Wong V.A., Roberts K., Jaiswal A.K., Gonzalez F.J., Butterworth B.E., Borghoff S., Parkinson H., Everitt J., Recio L. Cancer Res. 2003, 63:929-935.
61. Zhu H., Li Y., Trush M.A. J. Toxicol. Environ. Health 1995, 46:183-201.
62. Trush M.A., Twerdok L.E., Rembish S.J., Zhu H., Li Y. Environ. Health Perspect. 1996, 104(Suppl. 6):1227-1234.
63. Chandrasena R.E., Edirisinghe P.D., Bolton J.L., Thatcher G.R. Chem. Res. Toxicol. 2008, 21:1324-1329.
64. Gaikwad N.W., Rogan E.G., Cavalieri E.L. Free Radic. Biol. Med. 2007, 43:1289-1298.
65. Zahid M., Gaikwad N.W., Ali M.F., Lu F., Saeed M., Yang L., Rogan E.G., Cavalieri E.L. Free Radic. Biol. Med. 2008, 45:136-145.
66. Lu F., Zahid M., Wang C., Saeed M., Cavalieri E.L., Rogan E.G. Cancer Prev. Res. (Phila Pa) 2008, 1:135-145.
67. Montano M.M., Chaplin L.J., Deng H., Mesia-Vela S., Gaikwad N., Zahid M., Rogan E. Oncogene 2007, 26:3587-3590.
68. Singh S., Chakravarti D., Edney J.A., Hollins R.R., Johnson P.J., West W.W., Higginbotham S.M., Cavalieri E.L., Rogan E.G. Oncol. Rep. 2005, 14:1091-1096.
69. Wang X.J., Hayes J.D., Higgins L.G., Wolf C.R., Dinkova-Kostova A.T. Chem. Biol. 2010, 17:75-85.
70. Singh S., Zahid M., Saeed M., Gaikwad N.W., Meza J.L., Cavalieri E.L., Rogan E.G., Chakravarti D. J. Steroid Biochem. Mol. Biol. 2009, 117:56-66.
71. Fagerholm R., Hofstetter B., Tommiska J., Aaltonen K., Vrtel R., Syrjäkoski K., Kallioniemi A., Kilpivaara O., Mannermaa A., Kosma V.M., Uusitupa M., Eskelinen M., Kataja V., Aittomäki K., von Smitten K., Heikkilä P., Lukas J., Holli K., Bartkova J., Blomqvist C., Bartek J., Nevanlinna H. Nat. Genet. 2008, 40:844-853.
72. Zafar K.S., Siegel D., Ross D. Mol. Pharmacol. 2006, 70:1079-1086.
73. Zafar K.S., Inayat-Hussain S.H., Siegel D., Bao A., Shieh B., Ross D. Toxicol. Lett. 2006, 166:261-267.
74. Jia Z., Zhu H., Misra B.R., Li Y., Misra H.P. Neurochem. Res. 2008, 33:2197-2205.
75. Duffy S., So A., Murphy T.H. J. Neurochem. 1998, 71:69-77.
76. Hara H., Ohta M., Ohta K., Kuno S., Adachi T. Mol. Brain Res. 2003, 119:125-131.
77. Jia Z., Zhu H., Misra H.P., Li Y. Brain Res. 2008, 1197:159-169.
78. Jia Z., Zhu H., Li Y., Misra H.P. Neurochem. Res. 2009, 34:1924-1934.
79. Siebert A., Desai V., Chandrasekaran K., Fiskum G., Jafri M.S. J. Neurosci. Res. 2009, 87:1659-1669.
80. Lim J.H., Kim K.M., Kim S.W., Hwang O., Choi H.J. Pharmacol. Res. 2008, 57:325-331.
81. Weinreb O., Bar-Am O., Amit T., Drigues N., Sagi Y., Youdim M.B. Chem. Biol. Interact. 2008, 175:318-326.
82. Bar-Am O., Weinreb O., Amit T., Youdim M.B. J. Mol. Neurosci. 2009, 37:135-145.
83. Miyazaki I., Asanuma M., Diaz-Corrales F.J., Fukuda M., Kitaichi K., Miyoshi K., Ogawa N. FASEB J. 2006, 20:571-573.
84. Zafar K.S., Inayat-Hussain S.H., Ross D. J. Neurochem. 2007, 102:913-921.
85. Van Muiswinkel F.L., de Vos R.A., Bol J.G., Andringa G., Jansen Steur E.N., Ross D., Siegel D., Drukarch B. Neurobiol. Aging 2004, 25:1253-1262.
86. Raina A.K., Templeton D.J., Deak J.C., Perry G., Smith M.A. Redox Rep. 1999, 4:23-27.
87. SantaCruz K.S., Yazlovitskaya E., Collins J., Johnson J., DeCarli C. Neurobiol. Aging 2004, 25:63-69.
88. Harada S., Fujii C., Hayashi A., Ohkoshi N. Biochem. Biophys. Res. Commun. 2001, 288:887-892.
89. Shao M., Liu Z., Tao E., Chen B. Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2001, 18:122-124.
90. Wang B., Jin F., Xie Y., Tang Y., Kan R., Zheng C., Yang Z., Wang L. Neurosci. Lett. 2006, 409:179-181.
91. Dick F.D., De Palma G., Ahmadi A., Osborne A., Scott N.W., Prescott G.J., Bennett J., Semple S., Dick S., Mozzoni P., Haites N., Wettinger S.B., Mutti A., Otelea M., Seaton A., Soderkvist P., Felice A. Occup. Environ. Med. 2007, 64:673-680.
92. Bian J.T. J. Mol. Neurosci. 2008, 34:235-240.
93. Beyer R.E. Mol. Aspects Med. 1994, 15(Suppl.):s117-s129.
94. Beyer R.E., Segura-Aguilar J., Di Bernardo S., Cavazzoni M., Fato R., Fiorentini D., Galli M.C., Setti M., Landi L., Lenaz G. Mol. Aspects Med. 1997, 18(Suppl.):S15-S23.
95. Landi L., Fiorentini D., Galli M.C., Segura-Aguilar J., Beyer R.E. Free Radic. Biol. Med. 1997, 22:329-335.
96. Beyer R.E., Segura-Aguilar J., Di Bernardo S., Cavazzoni M., Fato R., Fiorentini D., Galli M.C., Setti M., Landi L., Lenaz G. Natl. Acad. Sci. USA 1996, 93:2528-2532.
97. Siegel D., Bolton E.M., Burr J.A., Liebler D.C., Ross D. Mol. Pharmacol. 1997, 52:300-305.
98. Long D.J., Gaikwad A., Multani A., Pathak S., Montgomery C.A., Gonzalez F.G., Jaiswal A.K. Cancer Res. 2002, 62:3030-3036.
99. Asher G., Lotem J., Cohen B., Sachs L., Shaul Y. Proc. Natl. Acad. Sci. USA 2001, 98:1188-1193.
100. Gaikwad A., Long D.J., Stringer J.L., Jaiswal A.K. J. Biol. Chem. 2001, 276:22559-22564.
101. Iskander K., Gaikwad A., Paquet M., Long D.J., Brayton C., Barrios R., Jaiswal A.K. Cancer Res. 2005, 65:2054-2058.
102. Thimmulappa R.K., Mai K.H., Srisuma S., Kensler T.W., Yamamoto M., Biswal S. Cancer Res. 2002, 62:5196-5203.
103. Wignall S.M., Gray N.S., Chang Y.T., Juarez L., Jacob R., Burlingame A., Schultz P.G., Heald R. Chem. Biol. 2004, 11:135-146.
104. Asher G., Lotem J., Kama R., Sachs L., Shaul Y. Proc. Natl. Acad. Sci. USA 2002, 99:3099-3104.
105. Gong X., Kole L., Iskander K., Jaiswal A.K. Cancer Res. 2007, 67:5380-5388.
106. Asher G., Lotem J., Sachs L., Kahana C., Shaul Y. Proc. Natl. Acad. Sci. USA 2002, 99:13125-13130.
107. Asher G., Lotem J., Tsvetkov P., Reiss V., Sachs L., Shaul Y. Proc. Natl. Acad. Sci. USA 2003, 100:15065-15070.
108. Anwar A., Dehn D. J. Biol. Chem. 2003, 278:10368-10373.
109. Asher G., Tsvetkov P., Kahana C., Shaul Y. Genes Dev. 2005, 19:316-321.
110. Asher G., Dym O., Tsvetkov P., Adler J., Shaul Y. Biochemistry 2006, 45:6372-6378.
111. Garate M., Wong R.P., Campos E.I., Wang Y., Li G. EMBO Rep. 2008, 9:576-581.
112. Asher G., Bercovich Z., Tsvetkov P., Shaul Y., Kahana C. Mol. Cell 2005, 17:645-655.
113. Alard A., Fabre B., Anesia R., Marboeuf C., Pierre P., Susini C., Bousquet C., Pyronnet S. Mol. Cell. Biol. 2010, 30:1097-1105.