Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 29, Issue 11, 2009, Pages 1851-1857

  Zakkar, Mustafa ^a   Van Der Heiden, Kim ^a   Luong, Le Anh ^a   Chaudhury, Hera ^a   Cuhlmann, Simon ^a,b   Hamdulay, Shahir S ^a   Krams, Rob ^b   Edirisinghe, Indika ^c   Rahman, Irfan ^c   Carlsen, Harald ^d   Haskard, Dorian O ^a   Mason, Justin C ^a   Evans, Paul C ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^d UNIVERSITY OF OSLO   (Norway)

Author keywords

Arterial endothelium; MKK3 6; MKP 1; Nrf2; P38; Proinflammatory activation; Shear stress; Sulforaphane

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; SULFORAPHANE; TRANSCRIPTION FACTOR NRF2; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL EXPERIMENT; ARTICLE; ATHEROSCLEROSIS; CELL ACTIVATION; CELL PROTECTION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME INACTIVATION; HUMAN; HUMAN CELL; INFLAMMATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SHEAR STRESS; SIGNAL TRANSDUCTION;

ANIMALS; ARTERIES; ARTERITIS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENDOTHELIAL CELLS; ENZYME ACTIVATION; INFLAMMATION MEDIATORS; MALE; MICE; MICE, INBRED C57BL; NF-E2-RELATED FACTOR 2; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; RANDOM ALLOCATION; SENSITIVITY AND SPECIFICITY; SHEAR STRENGTH; SIGNAL TRANSDUCTION; THIOCYANATES;

EID: 73949142348     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.109.193375     Document Type: Article

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