Protective effects of Brassica oleracea sprouts extract toward renal damage in high-salt-fed SHRSP: Role of AMPK/PPARa/UCP2 axis

Journal of Hypertension

Volumn 33, Issue 7, 2015, Pages 1465-1479

  Rubattu, Speranza ^a,b   Di Castro, Sara ^a   Cotugno, Maria ^a   Bianchi, Franca ^a   Mattioli, Roberto ^c   Baima, Simona ^d   Stanzione, Rosita ^a   Madonna, Michele ^a   Bozzao, Cristina ^b   Marchitti, Simona ^a   Gelosa, Paolo ^e   Sironi, Luigi ^e,f   Pignieri, Alice ^f   Maldini, Mariateresa ^d   Giusti, Anna Maria ^d,g   Nardini, Mirella ^d   Morelli, Giorgio ^d   Costantino, Paolo ^c   Volpe, Massimo ^a,b  

^a IRCCS NEUROMED   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d ISTITUTO NAZIONALE DELLA NUTRIZIONE   (Italy)

^e CENTRO CARDIOLOGICO MONZINO   (Italy)

^f UNIVERSITY OF MILAN   (Italy)

^g SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

AMPK PGC1 SIRT1 PPAR UCP2; Brassica oleracea; High salt diet; Hypertension; Renal damage; Stroke prone spontaneously hypertensive rat

Indexed keywords

ANTHOCYANIN; BRASSICA OLERACEA EXTRACT; CYANIDIN 3 GLUCOSIDE; FLAVONOID; GENIPIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MANGANESE SUPEROXIDE DISMUTASE; NITRIC OXIDE SYNTHASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PLANT EXTRACT; POLYPHENOL; PROTECTIVE AGENT; SODIUM CHLORIDE; SULFORAPHANE; UNCLASSIFIED DRUG; UNCOUPLING PROTEIN 2; ANTIOXIDANT; ION CHANNEL; IRIDOID; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN 2; SALT INTAKE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRASSICA OLERACEA; CELL VIABILITY; CONTROLLED STUDY; IN VITRO STUDY; INFLAMMATION; KIDNEY INJURY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN URINE LEVEL; PROTEINURIA; RAT; RENAL PROTECTION; SPROUT; STROKE PRONE SPONTANEOUSLY HYPERTENSIVE RAT; ADVERSE EFFECTS; ANIMAL; BLOOD PRESSURE; BRASSICA; CHEMICALLY INDUCED; CHEMISTRY; COMPLICATION; DIET; DRUG EFFECTS; GLOMERULUS; HYPERTENSION; KIDNEY DISEASES; KIDNEY PROXIMAL TUBULE; MESANGIUM; METABOLISM; PATHOLOGY; PHYSIOLOGY; SALT INTAKE; SEEDLING; SPONTANEOUSLY HYPERTENSIVE RAT; STROKE;

AMP-ACTIVATED PROTEIN KINASES; ANIMALS; ANTIOXIDANTS; BLOOD PRESSURE; BRASSICA; DIET; GLOMERULAR MESANGIUM; HYPERTENSION; ION CHANNELS; IRIDOIDS; KIDNEY DISEASES; KIDNEY GLOMERULUS; KIDNEY TUBULES, PROXIMAL; MITOCHONDRIAL PROTEINS; OXIDATIVE STRESS; PLANT EXTRACTS; PPAR ALPHA; PROTEINURIA; RATS; RATS, INBRED SHR; SEEDLINGS; SODIUM CHLORIDE, DIETARY; STROKE;

EID: 84938865951     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0000000000000562     Document Type: Article

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