Genotoxic bioactivation of constituents of a diesel exhaust particle extract by the human lung

Environmental and Molecular Mutagenesis

Volumn 54, Issue 3, 2013, Pages 158-171

  Iba, Michael M ^a   Caccavale, Robert J ^b  

^a RUTGERS UNIVERSITY   (United States)

^b SAINT PETER S UNIVERSITY HOSPITAL   (United States)

Author keywords

H2Ax; Ames test; CYP1A1; Diesel emissions; NQO1

Indexed keywords

ALPHA NAPHTHOFLAVONE; BIODIESEL; CYTOCHROME P450 1A1; CYTOCHROME P450 1A2; CYTOCHROME P450 2B6; CYTOCHROME P450 3A; DICOUMAROL; DIESEL EXHAUST PARTICLE EXTRACT; DOUBLE STRANDED DNA; HISTONE H2AX; KETOCONAZOLE; NQO1 PROTEIN; PROTEIN; TICLOPIDINE; UNCLASSIFIED DRUG;

AGED; ANIMAL EXPERIMENT; ARTICLE; BRONCHUS MUCOSA; CATALYSIS; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; EX VIVO STUDY; FEMALE; GENOTOXICITY; HUMAN; LUNG; LUNG ALVEOLUS; LUNG ALVEOLUS CELL; LUNG ALVEOLUS EPITHELIUM; LUNG PARENCHYMA; LUNG TOXICITY; MALE; MUTAGENICITY; NONHUMAN; OXIDATION; PROTEIN EXPRESSION; RAT; SALMONELLA TYPHIMURIUM;

AGED; AGED, 80 AND OVER; AIR POLLUTANTS; ANIMALS; BIOTRANSFORMATION; BLOTTING, WESTERN; CYTOCHROME P-450 CYP1A1; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; LIVER; LUNG; MALE; MUTAGENICITY TESTS; MUTAGENS; NAD(P)H DEHYDROGENASE (QUINONE); POLYCYCLIC HYDROCARBONS, AROMATIC; RATS; RATS, SPRAGUE-DAWLEY; SALMONELLA TYPHIMURIUM; TISSUE CULTURE TECHNIQUES; VEHICLE EMISSIONS;

RATTUS; SALMONELLA; SALMONELLA TYPHIMURIUM;

EID: 84875051043     PISSN: 08936692     EISSN: 10982280     Source Type: Journal    
DOI: 10.1002/em.21759     Document Type: Article

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