Phytochemicals inhibit catechol-O-methyltransferase activity in cytosolic fractions from healthy human mammary tissues: Implications for catechol estrogen-induced DNA damage

Toxicological Sciences

Volumn 81, Issue 2, 2004, Pages 316-324

  van Duursen, Marjorie B M ^a   Sanderson, J Thomas ^a   de Jong, Paul Chr ^b   Kraaij, Marlies ^a   van den Berg, Martin ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b ST ANTONIUS HOSPITAL   (Netherlands)

Author keywords

Catechol estrogens; COMT; DNA damage; Phytochemicals

Indexed keywords

2' FLUORO 3,4 DIHYDROXY 5 NITROBENZOPHENONE; CATECHIN; CATECHOL ESTROGEN; CATECHOL METHYLTRANSFERASE; CATECHOL METHYLTRANSFERASE INHIBITOR; CHRYSIN; DNA; EPICATECHIN; ESTRADIOL DERIVATIVE; FLAVONE; GENISTIN; PLANT MEDICINAL PRODUCT; QUERCETIN;

ARTICLE; BREAST; BREAST CARCINOGENESIS; BREAST REDUCTION; CATALYSIS; CHEMOSENSITIVITY; COMET ASSAY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSOL; DNA DAMAGE; ENZYME ACTIVITY; ENZYME INHIBITION; ESTROGEN METABOLISM; ESTROGEN SYNTHESIS; HORMONE INHIBITION; HUMAN; HUMAN TISSUE; IC 50; MUTAGENICITY;

BENZOPHENONES; BREAST; CATECHOL O-METHYLTRANSFERASE; CELL LINE, TUMOR; CELL SURVIVAL; COMET ASSAY; CYTOSOL; DNA DAMAGE; DNA, NEOPLASM; ENZYME INHIBITORS; ESTROGENS, CATECHOL; FEMALE; HUMANS; INDICATORS AND REAGENTS; ULTRAVIOLET RAYS;

MINK CELL FOCUS-FORMING VIRUS;

EID: 5744248613     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfh216     Document Type: Article

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