Declining signal dependence of Nrf2-MafS-regulated gene expression correlates with aging phenotypes

Aging Cell

Volumn 12, Issue 4, 2013, Pages 554-562

  Rahman, Mohammed Mahidur ^a,c   Sykiotis, Gerasimos P ^a,d   Nishimura, Mayuko ^b,e   Bodmer, Rolf ^b   Bohmann, Dirk ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b BURNHAM INSTITUTE   (United States)

^c INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^d UNIVERSITY OF PATRAS   (Greece)

^e KITASATO UNIVERSITY   (Japan)

Author keywords

Aging; Drosophila; Keap1; Nrf2; Oxidative stress; Small Maf

Indexed keywords

TRANSCRIPTION FACTOR MAF; TRANSCRIPTION FACTOR NRF2; CAP-N-COLLAR PROTEIN, DROSOPHILA; DROSOPHILA PROTEIN; MESSENGER RNA; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR;

AGING; ANTIOXIDANT ACTIVITY; ARTICLE; CELLULAR STRESS RESPONSE; DIMERIZATION; DROSOPHILA; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE TARGETING; HEART PERFORMANCE; MOTOR PERFORMANCE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ADAPTATION; ANIMAL; CELL LINE; FEMALE; GENETIC TRANSCRIPTION; GENETICS; HEART; MALE; METABOLISM; MOTOR ACTIVITY; OXIDATIVE STRESS; PHYSIOLOGY;

ADAPTATION, PHYSIOLOGICAL; AGING; ANIMALS; CELL LINE; DROSOPHILA; DROSOPHILA PROTEINS; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; MAF TRANSCRIPTION FACTORS, SMALL; MALE; MOTOR ACTIVITY; OXIDATIVE STRESS; PHENOTYPE; REPRESSOR PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 84880514122     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12078     Document Type: Article

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