Quinone reductase (QR) inducers from Andrographis paniculata and identification of molecular target of andrographolide

Fitoterapia

Volumn 83, Issue 8, 2012, Pages 1506-1513

  Yuan, Yonglei ^a   Ji, Long ^a   Luo, Liping ^a   Lu, Juan ^a   Ma, Xiaoqiong ^b   Ma, Zhongjun ^a   Chen, Zhe ^b  

^a ZHEJIANG UNIVERSITY   (China)

^b Chinese Traditional Medicine Hospital of Zhejiang Province   (China)

Author keywords

Andrographis paniculata; Andrographolide; Glutathione; Keap1; Quinone reductase

Indexed keywords

11,12 DIDEHYDRO 14 DEOXYANDROGRAPHOLIDE; 14 DEOXY 14,15 DEHYDROANDROGRAPHOLIDE; 14 DEOXYANDROGRAPHOLIDE; 19 HYDROXY 3 OXOENT LABDA 8(17),11,13 TRIEN 16,15 OLIDE; 3 HYDROXY 19 OXO ENT LABDA 8(17),11,13 TRIEN 16,15 OLIDE; 3 HYDROXY 4,7 MEGASTIGMADIEN 9 ONE; 3 HYDROXY BETA IONONE; 3,14 DIDEOXYANDROGRAPHOLIDE; 3H INDOLE 3 CARBOXALDEHYDE; 5 HYDROXY 7,8 DIMETHOXYFLAVONE; 7 HYDROXY 3',4' DIMETHOXYISOFLAVONONE; ALKYLATING AGENT; ANDROGRAPHIS PANICULATA EXTRACT; ANDROGRAPHOLIDE; ANDROGRAPHOSIDE; BISANDROGRAPHOLIDE D; CYSTEINE; DEHYDROVOMIFOLIOL; DIHYDROCLADRIN; DITERPENOID; GLUTATHIONE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; LOLIOLIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); SESQUITERPENE; UNCLASSIFIED DRUG;

ALKYLATION; ANDROGRAPHIS PANICULATA; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG SCREENING; ENZYME ACTIVITY; ENZYME MODIFICATION; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICHAEL ADDITION; NONHUMAN; PHYTOCHEMISTRY; PRIORITY JOURNAL;

ANDROGRAPHIS; CELL LINE; DITERPENES; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR STRUCTURE; PLANT EXTRACTS; QUINONE REDUCTASES; RECOMBINANT PROTEINS;

ANDROGRAPHIS PANICULATA;

EID: 84870782936     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2012.08.018     Document Type: Article

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