Personalised nutrition: Status and perspectives

British Journal of Nutrition

Volumn 98, Issue 1, 2007, Pages 26-31

  Joost, Hans Georg ^a   Gibney, Michael J ^b   Cashman, Kevin D ^c   Görman, Ulf ^d   Hesketh, John E ^e   Mueller, Michael ^f   van Ommen, Ben ^g   Williams, Christine M ^h   Mathers, John C ^e  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b ST JAMES S HOSPITAL   (Ireland)

^c UNIVERSITY COLLEGE CORK   (Ireland)

^d LUND UNIVERSITY   (Sweden)

^e NEWCASTLE UNIVERSITY   (United Kingdom)

^f WAGENINGEN UNIVERSITY   (Netherlands)

^g TNO   (Netherlands)

^h UNIVERSITY OF READING   (United Kingdom)

Author keywords

Disease risk; Genotype; Nutrigenetics; Nutrigenomics; Nutritional recommendations

Indexed keywords

ACYLTRANSFERASE; GLUTATHIONE TRANSFERASE; XENOBIOTIC AGENT;

CARCINOGENESIS; CHOLESTEROL METABOLISM; CHRONIC DISEASE; DIABETES MELLITUS; DIETARY INTAKE; ENVIRONMENTAL FACTOR; FAMILIAL HYPERLIPEMIA; FOOD COMPOSITION; GENE INTERACTION; GENE MUTATION; GENETIC COUNSELING; GENETIC HETEROGENEITY; GENETIC SCREENING; GENETIC VARIABILITY; GENOTYPE; GENOTYPE PHENOTYPE CORRELATION; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; MENTAL DEFICIENCY; NONHUMAN; NUTRIENT SUPPLY; NUTRIGENOMICS; NUTRITIONAL ASSESSMENT; NUTRITIONAL STATUS; NUTRITIONAL VALUE; REVIEW; RISK BENEFIT ANALYSIS; RISK FACTOR; RISK REDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM;

CHRONIC DISEASE; FOOD; GENOTYPE; HUMANS; MODELS, GENETIC; NUTRITION DISORDERS; NUTRITION PHYSIOLOGY; NUTRITIONAL REQUIREMENTS; RESEARCH;

EID: 34547989732     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114507685195     Document Type: Review

References (41)

1. Ambrosone CB, Freudenheim JL, Thompson PA, Bowman E, Vena JE, Marshall JR, Graham S, Laughlin P, Nemoto T & Shields PG (1999) Manganese superoxide dismutase (MnSOD) genetic polymorphisms, dietary antioxidants, and risk of breast cancer. Cancer Res 59, 602-606.
2. Cai Q, Shu XO, Wen W, Cheng JR, Dai Q, Gao YT & Zheng W (2004) Genetic polymorphism in the manganese superoxide dismutase gene, antioxidant intake, and breast cancer risk: Results from the Shanghai Breast Cancer Study. Breast Cancer Res 6, R647-R655.
3. Cardon LR & Bell JI (2001) Association study designs for complex diseases. Nat Rev Genet 2, 91-99.
4. Cashman KD (2005) Homocysteine and osteoporotic fracture risk: A potential role for B vitamins. Nutr Rev 63, 29-36.
5. Colditz GA, Willett WC, Rotnitzky A & Manson JE (1995) Weight gain as a risk factor for clinical diabetes mellitus in women. Ann Intern Med 122, 481-486.
6. Cusack S & Cashman KD (2003) Impact of genetic variation on metabolic response of bone to diet. Proc Nutr Soc 62, 901-912.
7. Davis CD & Milner J (2004) Frontiers in nutrigenomics, proteomics, metabolomics and cancer prevention. Mutat Res 551, 51-64.
8. Deitz AC, Zheng W, Leff MA, Gross M, Wen WQ, Doll MA, Xiao GH, Folsom AR & Hein DW (2000) N-Acetyltransferase-2 genetic polymorpbism, well-done meat intake, and breast cancer risk among postmenopausal women. Cancer Epidemiol Biomarkers Prev 9, 905-910.
9. Dolinoy DC, Weidman JR, Waterland RA & Jirtle RL (2006) Maternal genistein alters coat color and protects Avy mouse offspring from obesity by modifying the fetal epigenome. Environ Health Perspect 11, 567-572.
10. Enattah NS, Sahi T, Savilahti E, Terwilliger JD, Peltonen L & Jarvela I (2002) Identification of a variant associated with adult-type hypolactasia. Nat Genet 30, 233-237.
11. Feuk L, Marshall CR, Wintle RF & Scherer SW (2006) Structural variants: changing the landscape of chromosomes and design of disease studies. Hum Mol Genet 15 (Spec. No. 1), R57-R66.
12. Gaskell G, Allum N & Stares S (2003) Europeans and biotechnology in 2002. Eurobarometer 58-0. http://www.ec.europa.eu/public_opinion/ archives/ebs/ebs_177_en.pdf.
13. German JB, Bauman DE, Burrin DG, et al. (2004) Metabolomics in the opening decade of the 21st century: Building the roads to individualized health. J Nutr 134, 2729-2732.
14. Helgadottir A, Manolescu A, Helgason A, et al. (2006) A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction. Nat Genetics 38, 68-74.
15. Hesketh J, Wybranska J, Dommels Y, King M, Ellitot R, Pico C & Keijer J (2006) Nutrient-gene interactions in benefit-risk analysis. Br J Nutr 95, 1232-1236.
16. Hinds DA, Stuve LL, Nilsen GB, Halperin E, Eskin E, Ballinger DG, Frazer KA & Cox DR (2005) Whole-genome patterns of common DNA variation in three human populations. Science 307, 1072-1079.
17. Hirschhorn JN, Lohmuelter K, Byrne E & Hirschhorn K (2002) A comprehensive review of genetic association studies. Genet Med 4, 45-61.
18. Jaenisch R & Bird A (2003) Epigenetic regulation of gene expression: How the genome integrates intrinsic and environmental signals. Nat Genetics 33, Suppl., 245-254.
19. Joint WHO/Food and Agriculture Association Expert Consultation (2003) Diet, Nutrition, and the Prevention of chronic Diseases. WHO Technical Report Series No. 916. http://www.who.int/dietphysicalactivity/ publications/trs916/en/
20. Joseph MA, Moysich KB, Freudenheim JL, Shields PG, Bowman ED, Zhang Y, Marshall JR & Ambrosone CB (2004) Cruciferous vegetables, genetic polymorphisms in glutathione S-transferases M1 and T1, and prostate cancer risk. Nutr Cancer 50, 206-213.
21. Kaput J, Ordovas JM, Ferguson L, et al. (2005) The case for strategic international alliances to harness nutritional genomics for public and personal health. Br J Nutr 94, 623-632.
22. Kaput J & Rodriguez RL (2004) Nutritional genomics: The next frontier in the postgenomic era. Physiol Genomics 16, 166-177.
23. Knoblauch H, Bauerfeind A, Toliat MR, et al. (2004) Haplotypes and SNPs in 13 lipid-relevant genes explain most of the genetic variance in high-density lipoprotein and low-density lipoprotein cholesterol. Hum Mol Genet 13, 993-1004.
24. Levy HL (1999) Phenylketonuria: Old disease, new approach to treatment. Proc Natl Acad Sci U S A 96, 1811-1813.
25. Li H, Kantoff PW, Giovannucci E, Leitzmann MF, Gaziano JM, Stampfer MJ & Ma J (2005) Manganese superoxide dismutase polymorphism, prediagnostic antioxidant status, and risk of clinical significant prostate cancer. Cancer Res 65, 2498-24504.
26. Loktionov A, Scollen S, McKeown N & Bingham SA (2000) Gene-nutrient interactions: Dietary behaviour associated with high coronary heart disease risk particularly affects serum LDL cholesterol in apolipoprotein E epsilon4-carrying free-living individuals. Br J Nutr 84, 885-890.
27. Mathers JC (2002) Pulses and carcinogenesis: Potential for the prevention of colon, breast and other cancers. Br J Nutr 88, Suppl. 3, S273-S279.
28. Nishina PM, Wang J, Toyofuku W, Kuypers FA, Ishida BY & Paigen B (1993) Atherosclerosis and plasma and liver lipids in nine inbred strains of mice. Lipids 28, 599-605.
29. Ordovas JM (2004) The quest for cardiovascular health in the genomic era: Nutrigenetics and plasma lipoproteins. Proc Nutr Soc 63 145-152.
30. Ordovas JM & Corella D (2004) Nutritional genomics. Annu Rev Genomics Hum Genet 5, 71-118.
31. Ordovas JM, Corella D, Cupples LA, Demissie S, Kelleher A, Coltell O, Wilson PW, Schaefer EJ & Tucker K (2002) Polyunsaturated fatty acids modulate the effects of the APOA1 G-A polymorphism on HDL-cholesterol concentrations in a sex-specific manner: The Framingham, Study. Am J Clin Nutr 75, 38-46.
32. Payseur BA, Clark AG, Hixson J, Boerwinkle E & Sing CF (2006) Contrasting multi-site genotypic distributions among discordant quantitative phenotypes: The APOA1/C3/A4/A5 gene cluster and cardiovascular disease risk factors. Genetic Epidemiol 30, 508-518.
33. Plum L, Giesen K, Kluge R, Junger E, Linnartz K, Schürmann A, Becker W & Joost HG (2002) Characterisation of the mouse diabetes susceptibility locus Nidd/SJL: Islet cell destruction, interaction with the obesity QTL Nob1, and effect of dietary fat. Diabetologia 45, 823-830.
34. Redon R, Ishikawa S, Fitch KR, et al. (2006) Global variation in copy number in the human genome. Nature 444, 444-454.
35. Russo G (2006) Home health tests are 'genetic horoscopes'. Nature 442, 497.
36. Seow A, Yuan JM, Sun CL, Van Den Berg D, Lee HP & Yu MC (2002) Dietary isothiocyanates, glutathione S-transferase polymorphisms and colorectal cancer risk in the Singapore Chinese Health Study. Carcinogenesis 23, 2055-2061.
37. Sharp L & little J (2004) Polymorphisms in folate metabolism and colorectal neoplasia: A HuGE review. Am J Epidemiol 159, 423-443.
38. Song Y, Niu T, Manson JE, Kwiatkowski DJ & Liu S (2004) Are variants in the CAPN10 gene related to risk of type 2 diabetes? A quantitative assessment of population and family-based association studies. Am J Hum Genet 74, 208-222.
39. Strain JJ, Dowey L, Ward M, Pentieva K & McNulty H (2004) B-vitamins, homocysteine metabolism and CVD. Proc Nutr Soc 63, 597-603.
40. van Ommen B & Stierum R (2002) Nutrigenomics: Exploiting systems biology in the nutrition and health arena. Curr Opin Biotechnol 13, 517-521.
41. Wuschke S, Dahm S, Schmidt C, Joost HG & Al-Hasani H (2006) A meta-analysis of QTL associated with body weight and adiposity in mice. Int J Obesity Published online. DOI:10.1038/sj.ijo.0803473.