Therapeutic potential of the endocrine fibroblast growth factors FGF19, FGF21 and FGF23

Nature Reviews Drug Discovery

Volumn 15, Issue 1, 2016, Pages 51-69

  Degirolamo, Chiara ^a,b,c   Sabbà, Carlo ^a   Moschetta, Antonio ^a,b  

^a UNIVERSITY OF BARI   (Italy)

^b NATIONAL CANCER INSTITUTE GIOVANNI PAOLO II   (Italy)

^c Letscom Srl   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMG 876; CALCITRIOL; CALCIUM CARBONATE; COMPLEMENT COMPONENT C4; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; FARNESOID X RECEPTOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 19; FIBROBLAST GROWTH FACTOR 21; FIBROBLAST GROWTH FACTOR 23; KRN 23; LY 2405319; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUROPEPTIDE Y; NGM 282; OBETICHOLIC ACID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PF 05231023; PLACEBO; PROTEIN KINASE B; PROTEIN TYROSINE PHOSPHATASE SHP 2; PX 104; RECOMBINANT FIBROBLAST GROWTH FACTOR 21; SEVELAMER CARBONATE; SRT 2379; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; UNCLASSIFIED DRUG; UNINDEXED DRUG; URSODEOXYCHOLIC ACID; VITAMIN D RECEPTOR; FGF19 PROTEIN, HUMAN; NEW DRUG;

ADAPTATION; BILIARY CIRRHOSIS; BINDING AFFINITY; CARDIOVASCULAR DISEASE; CHRONIC KIDNEY DISEASE; DIABETES MELLITUS; ENERGY EXPENDITURE; GENE CONTROL; HUMAN; INFLAMMATORY BOWEL DISEASE; INSULIN SENSITIVITY; LIVER CELL CARCINOMA; MALIGNANT NEOPLASTIC DISEASE; METABOLIC REGULATION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; OXIDATIVE STRESS; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); PHASE 4 CLINICAL TRIAL (TOPIC); PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REVIEW; SHORT BOWEL SYNDROME; SIGNAL TRANSDUCTION; THERMOGENESIS; UPREGULATION; X LINKED HYPOPHOSPHATEMIC RICKETS; AGONISTS; ANIMAL; BIOLOGICAL MODEL; CHRONIC DISEASE; HOMEOSTASIS; PHYSIOLOGY;

ANIMALS; CHRONIC DISEASE; DRUGS, INVESTIGATIONAL; FIBROBLAST GROWTH FACTORS; HOMEOSTASIS; HUMANS; MODELS, BIOLOGICAL;

EID: 84955209323     PISSN: 14741776     EISSN: 14741784     Source Type: Journal    
DOI: 10.1038/nrd.2015.9     Document Type: Review

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