Selective activation of nuclear bile acid receptor FXR in the intestine protects mice against cholestasis

Gastroenterology

Volumn 142, Issue 2, 2012, Pages

  Modica, Salvatore ^a   Petruzzelli, Michele ^a,b   Bellafante, Elena ^a   Murzilli, Stefania ^a   Salvatore, Lorena ^a   Celli, Nicola ^a   Di Tullio, Giuseppe ^a   Palasciano, Giuseppe ^b   Moustafa, Tarek ^c   Halilbasic, Emina ^c,d   Trauner, Michael ^c,d   Moschetta, Antonio ^a,b  

^a Laboratory of Lipid Metabolism and Cancer   (Italy)

^b UNIVERSITY OF BARI   (Italy)

^c MEDICAL UNIVERSITY OF GRAZ   (Austria)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

ANIT; BDL; Fibrosis; Mouse Model

Indexed keywords

1 NAPHTHYL ISOTHIOCYANATE; BILE ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE; FARNESOID X RECEPTOR; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 15; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BILE ACID BLOOD LEVEL; BILE DUCT LIGATION; CHOLESTASIS; CONTROLLED STUDY; DISEASE COURSE; EXTRAHEPATIC BILE DUCT OBSTRUCTION; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; INTESTINE; INTRAHEPATIC CHOLESTASIS; LIVER INJURY; LIVER PROTECTION; LOSS OF FUNCTION MUTATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

EID: 84856159269     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.10.028     Document Type: Article

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