메뉴 건너뛰기




Volumn 86, Issue 6, 2014, Pages 1106-1115

Parathyroid hormone activates the orphan nuclear receptor Nurr1 to induce FGF23 transcription

Author keywords

Calcium sensing receptor; Chronic kidney failure; FGF23; Parathyroid hormone

Indexed keywords

CALCIMIMETIC AGENT; CALCIUM; CREATININE; CYCLIC AMP DEPENDENT PROTEIN KINASE; DACTINOMYCIN; FIBROBLAST GROWTH FACTOR 23; MESSENGER RNA; NUCLEAR RECEPTOR RELATED FACTOR 1; ORPHAN NUCLEAR RECEPTOR; PARATHYROID HORMONE; PHOSPHATE; SHORT HAIRPIN RNA; TECALCET;

EID: 84964267910     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2014.215     Document Type: Article
Times cited : (120)

References (52)
  • 1
    • 84873658813 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 and Klotho: Physiology and pathophysiology of an endocrine network of mineral metabolism
    • Hu MC, Shiizaki K, Kuro-o M et al. Fibroblast growth factor 23 and Klotho: physiology and pathophysiology of an endocrine network of mineral metabolism.. Annu Rev Physiol 2013; 75: 503-533.
    • (2013) Annu Rev Physiol , vol.75 , pp. 503-533
    • Hu, M.C.1    Shiizaki, K.2    Kuro-O, M.3
  • 2
    • 2142746439 scopus 로고    scopus 로고
    • FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis
    • Shimada T, Hasegawa H, Yamazaki Y et al. FGF-23 is a potent regulator of vitamin D metabolism and phosphate homeostasis. J Bone Miner Res 2004; 19: 429-435.
    • (2004) J Bone Miner Res , vol.19 , pp. 429-435
    • Shimada, T.1    Hasegawa, H.2    Yamazaki, Y.3
  • 3
    • 0037462746 scopus 로고    scopus 로고
    • Human fibroblast growth factor-23 mutants suppress Na-dependent phosphate co-transport activity and 1alpha,25-dihydroxyvitamin D3 production
    • Saito H, Kusano K, Kinosaki M et al. Human fibroblast growth factor-23 mutants suppress Na-dependent phosphate co-transport activity and 1alpha,25-dihydroxyvitamin D3 production. J Biol Chem 2003; 278: 2206-2211.
    • (2003) J Biol Chem , vol.278 , pp. 2206-2211
    • Saito, H.1    Kusano, K.2    Kinosaki, M.3
  • 4
    • 59649091992 scopus 로고    scopus 로고
    • In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23)-mediated regulation of systemic phosphate homeostasis
    • Nakatani T, Sarraj B, Ohnishi M et al. In vivo genetic evidence for klotho-dependent, fibroblast growth factor 23 (Fgf23)-mediated regulation of systemic phosphate homeostasis. FASEB J 2009; 23: 433-441.
    • (2009) FASEB J , vol.23 , pp. 433-441
    • Nakatani, T.1    Sarraj, B.2    Ohnishi, M.3
  • 5
    • 36849017126 scopus 로고    scopus 로고
    • The parathyroid is a target organ for FGF23 in rats
    • Ben Dov IZ, Galitzer H, Lavi-Moshayoff V et al. The parathyroid is a target organ for FGF23 in rats. J Clin Invest 2007; 117: 4003-4008.
    • (2007) J Clin Invest , vol.117 , pp. 4003-4008
    • Ben Dov, I.Z.1    Galitzer, H.2    Lavi-Moshayoff, V.3
  • 6
    • 35848947037 scopus 로고    scopus 로고
    • Fibroblast growth factor-23 regulates parathyroid hormone and 1alpha-hydroxylase expression in cultured bovine parathyroid cells
    • Krajisnik T, Bjorklund P, Marsell R et al. Fibroblast growth factor-23 regulates parathyroid hormone and 1alpha-hydroxylase expression in cultured bovine parathyroid cells. J Endocrinol 2007; 195: 125-131.
    • (2007) J Endocrinol , vol.195 , pp. 125-131
    • Krajisnik, T.1    Bjorklund, P.2    Marsell, R.3
  • 7
    • 74449094013 scopus 로고    scopus 로고
    • Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease
    • Galitzer H, Ben Dov IZ, Silver J et al. Parathyroid cell resistance to fibroblast growth factor 23 in secondary hyperparathyroidism of chronic kidney disease. Kidney Int 2010; 77: 211-218.
    • (2010) Kidney Int , vol.77 , pp. 211-218
    • Galitzer, H.1    Ben Dov, I.Z.2    Silver, J.3
  • 9
    • 74449086740 scopus 로고    scopus 로고
    • Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients
    • Komaba H, Goto S, Fujii H et al. Depressed expression of Klotho and FGF receptor 1 in hyperplastic parathyroid glands from uremic patients. Kidney Int 2010; 77: 232-238.
    • (2010) Kidney Int , vol.77 , pp. 232-238
    • Komaba, H.1    Goto, S.2    Fujii, H.3
  • 10
    • 26444484606 scopus 로고    scopus 로고
    • Effects of parathyroid hormone on Wnt signaling pathway in bone
    • Kulkarni NH, Halladay DL, Miles RR et al. Effects of parathyroid hormone on Wnt signaling pathway in bone. J Cell Biochem 2005; 95: 1178-1190.
    • (2005) J Cell Biochem , vol.95 , pp. 1178-1190
    • Kulkarni, N.H.1    Halladay, D.L.2    Miles, R.R.3
  • 11
    • 84876054771 scopus 로고    scopus 로고
    • Critical role of parathyroid hormone (PTH) receptor-1 phosphorylation in regulating acute responses to PTH
    • Maeda A, Okazaki M, Baron DM et al. Critical role of parathyroid hormone (PTH) receptor-1 phosphorylation in regulating acute responses to PTH. PNAS 2013; 110: 5864-5869.
    • (2013) PNAS , vol.110 , pp. 5864-5869
    • Maeda, A.1    Okazaki, M.2    Baron, D.M.3
  • 12
    • 69249106380 scopus 로고    scopus 로고
    • High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients
    • Jean G, Terrat JC, Vanel T et al. High levels of serum fibroblast growth factor (FGF)-23 are associated with increased mortality in long haemodialysis patients. Nephrol Dial Transplant 2009; 24: 2792-2796.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 2792-2796
    • Jean, G.1    Terrat, J.C.2    Vanel, T.3
  • 13
    • 79958724181 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease
    • Isakova T, Xie HL, Yang W et al. Fibroblast growth factor 23 and risks of mortality and end-stage renal disease in patients with chronic kidney disease. JAMA 2011; 305: 2432-2439.
    • (2011) JAMA , vol.305 , pp. 2432-2439
    • Isakova, T.1    Xie, H.L.2    Yang, W.3
  • 14
    • 77957993384 scopus 로고    scopus 로고
    • PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: A bone parathyroid feedback loop
    • Lavi-Moshayoff V, Wasserman G, Meir T et al. PTH increases FGF23 gene expression and mediates the high-FGF23 levels of experimental kidney failure: A bone parathyroid feedback loop. Am J Physiol Renal Physiol 2010; 299: F882-F889.
    • (2010) Am J Physiol Renal Physiol , vol.299 , pp. F882-F889
    • Lavi-Moshayoff, V.1    Wasserman, G.2    Meir, T.3
  • 15
    • 81255194004 scopus 로고    scopus 로고
    • Cinacalcet treatment and serum FGF23 levels in haemodialysis patients with secondary hyperparathyroidism
    • Koizumi M, Komaba H, Nakanishi S et al. Cinacalcet treatment and serum FGF23 levels in haemodialysis patients with secondary hyperparathyroidism. Nephrol Dial Transplant 2012; 27: 784-790.
    • (2012) Nephrol Dial Transplant , vol.27 , pp. 784-790
    • Koizumi, M.1    Komaba, H.2    Nakanishi, S.3
  • 16
    • 0038526314 scopus 로고    scopus 로고
    • Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors
    • Wang Z, Benoit G, Liu J et al. Structure and function of Nurr1 identifies a class of ligand-independent nuclear receptors. Nature 2003; 423: 555-560.
    • (2003) Nature , vol.423 , pp. 555-560
    • Wang, Z.1    Benoit, G.2    Liu, J.3
  • 17
    • 0031866761 scopus 로고    scopus 로고
    • The NGFI-B subfamily of the nuclear receptor superfamily (review)
    • Maruyama K, Tsukada T, Ohkura N et al. The NGFI-B subfamily of the nuclear receptor superfamily (review). Int J Oncol 1998; 12: 1237-1243.
    • (1998) Int J Oncol , vol.12 , pp. 1237-1243
    • Maruyama, K.1    Tsukada, T.2    Ohkura, N.3
  • 18
    • 0035100243 scopus 로고    scopus 로고
    • Parathyroid hormone induces expression of the nuclear orphan receptor Nurr1 in bone cells
    • Tetradis S, Bezouglaia O, Tsingotjidou A. Parathyroid hormone induces expression of the nuclear orphan receptor Nurr1 in bone cells. Endocrinology 2001; 142: 663-670.
    • (2001) Endocrinology , vol.142 , pp. 663-670
    • Tetradis, S.1    Bezouglaia, O.2    Tsingotjidou, A.3
  • 19
    • 2542527677 scopus 로고    scopus 로고
    • Regulation of the osteopontin gene by the orphan nuclear receptor NURR1 in osteoblasts
    • Lammi J, Huppunen J, Aarnisalo P. Regulation of the osteopontin gene by the orphan nuclear receptor NURR1 in osteoblasts. Mol Endocrinol 2004; 18: 1546-1557.
    • (2004) Mol Endocrinol , vol.18 , pp. 1546-1557
    • Lammi, J.1    Huppunen, J.2    Aarnisalo, P.3
  • 20
    • 11144238245 scopus 로고    scopus 로고
    • Nuclear orphan receptor Nurr1 directly transactivates the osteocalcin gene in osteoblasts
    • Pirih FQ, Tang A, Ozkurt IC et al. Nuclear orphan receptor Nurr1 directly transactivates the osteocalcin gene in osteoblasts. J Biol Chem 2004; 279: 53167-53174.
    • (2004) J Biol Chem , vol.279 , pp. 53167-53174
    • Pirih, F.Q.1    Tang, A.2    Ozkurt, I.C.3
  • 21
    • 19444385546 scopus 로고    scopus 로고
    • Parathyroid hormone induces the NR4A family of nuclear orphan receptors in vivo
    • Pirih FQ, Aghaloo TL, Bezouglaia O et al. Parathyroid hormone induces the NR4A family of nuclear orphan receptors in vivo. Biochem Biophys Res Commun 2005; 332: 494-503.
    • (2005) Biochem Biophys Res Commun , vol.332 , pp. 494-503
    • Pirih, F.Q.1    Aghaloo, T.L.2    Bezouglaia, O.3
  • 22
    • 0026434553 scopus 로고
    • Identification of the Dna-binding site for NGFI-B by genetic selection in yeast
    • Wilson TE, Fahrner TJ, Johnston M et al. Identification of the Dna-binding site for NGFI-B by genetic selection in yeast. Science 1991; 252: 1296-1300.
    • (1991) Science , vol.252 , pp. 1296-1300
    • Wilson, T.E.1    Fahrner, T.J.2    Johnston, M.3
  • 23
    • 0028946634 scopus 로고
    • A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1
    • Perlmann T, Jansson L. A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1. Genes Dev 1995; 9: 769-782.
    • (1995) Genes Dev , vol.9 , pp. 769-782
    • Perlmann, T.1    Jansson, L.2
  • 24
    • 0031002024 scopus 로고    scopus 로고
    • Dopamine neuron agenesis in Nurr1-deficient mice
    • Zetterstrom RH, Solomin L, Jansson L et al. Dopamine neuron agenesis in Nurr1-deficient mice. Science 1997; 276: 248-250.
    • (1997) Science , vol.276 , pp. 248-250
    • Zetterstrom, R.H.1    Solomin, L.2    Jansson, L.3
  • 25
    • 79960015625 scopus 로고    scopus 로고
    • Schizophrenia-relevant behaviors in a genetic mouse model of constitutive Nurr1 deficiency
    • Vuillermot S, Joodmardi E, Perlmann T et al. Schizophrenia-relevant behaviors in a genetic mouse model of constitutive Nurr1 deficiency. Genes Brain Behav 2011; 10: 589-603.
    • (2011) Genes Brain Behav , vol.10 , pp. 589-603
    • Vuillermot, S.1    Joodmardi, E.2    Perlmann, T.3
  • 26
    • 69449107033 scopus 로고    scopus 로고
    • Novel regulators of Fgf23 expression and mineralization in Hyp bone
    • Liu SG, Tang W, Fang JW et al. Novel regulators of Fgf23 expression and mineralization in Hyp bone. Mol Endocrinol 2009; 23: 1505-1518.
    • (2009) Mol Endocrinol , vol.23 , pp. 1505-1518
    • Liu, S.G.1    Tang, W.2    Fang, J.W.3
  • 27
    • 3242875213 scopus 로고    scopus 로고
    • MotifViz: An analysis and visualization tool for motif discovery
    • Fu YT, Frith MC, Haverty PM et al. MotifViz: An analysis and visualization tool for motif discovery. Nucl Acids Res 2004; 32: W420-W423.
    • (2004) Nucl Acids Res , vol.32 , pp. W420-W423
    • Fu, Y.T.1    Frith, M.C.2    Haverty, P.M.3
  • 28
    • 58149179991 scopus 로고    scopus 로고
    • The PAZAR database of gene regulatory information coupled to the ORCA toolkit for the study of regulatory sequences
    • Portales-Casamar E, Arenillas D, Lim J et al. The PAZAR database of gene regulatory information coupled to the ORCA toolkit for the study of regulatory sequences. Nucl Acids Res 2009; 37: D54-D60.
    • (2009) Nucl Acids Res , vol.37 , pp. D54-D60
    • Portales-Casamar, E.1    Arenillas, D.2    Lim, J.3
  • 29
    • 33645460160 scopus 로고    scopus 로고
    • Increased parathyroid hormone gene expression in secondary hyperparathyroidism of experimental uremia is reversed by calcimimetics: Correlation with posttranslational modification of the trans acting factor AUF1
    • Levi R, Ben Dov IZ, Lavi-Moshayoff V et al. Increased parathyroid hormone gene expression in secondary hyperparathyroidism of experimental uremia is reversed by calcimimetics: correlation with posttranslational modification of the trans acting factor AUF1. J Am Soc Nephrol 2006; 17: 107-112.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 107-112
    • Levi, R.1    Ben Dov, I.Z.2    Lavi-Moshayoff, V.3
  • 30
    • 35848930014 scopus 로고    scopus 로고
    • Regulation of fibroblast growth factor-23 in chronic kidney disease
    • Westerberg PA, Linde T, Wikstrom B et al. Regulation of fibroblast growth factor-23 in chronic kidney disease. Nephrol Dial Transplant 2007; 22: 3202-3207.
    • (2007) Nephrol Dial Transplant , vol.22 , pp. 3202-3207
    • Westerberg, P.A.1    Linde, T.2    Wikstrom, B.3
  • 31
    • 79957870135 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease
    • Isakova T, Wahl P, Vargas GS et al. Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease. Kidney Int 2011; 79: 1370-1378.
    • (2011) Kidney Int , vol.79 , pp. 1370-1378
    • Isakova, T.1    Wahl, P.2    Vargas, G.S.3
  • 32
    • 70349934206 scopus 로고    scopus 로고
    • Effects of hPTH(1-34) infusion on circulating serum phosphate, 1,25-dihydroxyvitamin D, and FGF23 levels in healthy men
    • Burnett-Bowie SA, Henao MP, Dere ME et al. Effects of hPTH(1-34) infusion on circulating serum phosphate, 1,25-dihydroxyvitamin D, and FGF23 levels in healthy men. J Bone Min Res 2009; 24: 1681-1685.
    • (2009) J Bone Min Res , vol.24 , pp. 1681-1685
    • Burnett-Bowie, S.A.1    Henao, M.P.2    Dere, M.E.3
  • 33
    • 33646367420 scopus 로고    scopus 로고
    • Fibroblast growth factor 23 is a counterregulatory phosphaturic hormone for vitamin D
    • Liu S, Tang W, Zhou J et al. Fibroblast growth factor 23 is a counterregulatory phosphaturic hormone for vitamin D. J Am Soc Nephrol 2006; 17: 1305-1315.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 1305-1315
    • Liu, S.1    Tang, W.2    Zhou, J.3
  • 34
    • 34248577022 scopus 로고    scopus 로고
    • Molecular and cellular mechanisms of the anabolic effect of intermittent PTH
    • Jilka RL. Molecular and cellular mechanisms of the anabolic effect of intermittent PTH. Bone 2007; 40: 1434-1446.
    • (2007) Bone , vol.40 , pp. 1434-1446
    • Jilka, R.L.1
  • 35
    • 67649802514 scopus 로고    scopus 로고
    • Parathyroid hormone signaling in bone and kidney
    • Lee M, Partridge NC. Parathyroid hormone signaling in bone and kidney. Curr Opin Nephrol Hypertens 2009; 18: 298-302.
    • (2009) Curr Opin Nephrol Hypertens , vol.18 , pp. 298-302
    • Lee, M.1    Partridge, N.C.2
  • 36
    • 84885300497 scopus 로고    scopus 로고
    • Plasma FGF23 levels increase rapidly after acute kidney injury
    • Christov M, Waikar SS, Pereira RC et al. Plasma FGF23 levels increase rapidly after acute kidney injury. Kidney Int 2013; 84: 776-785.
    • (2013) Kidney Int , vol.84 , pp. 776-785
    • Christov, M.1    Waikar, S.S.2    Pereira, R.C.3
  • 37
    • 79953701946 scopus 로고    scopus 로고
    • Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses
    • Powell WF, Barry KJ, Tulum I et al. Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses. J Endocrinol 2011; 209: 21-32.
    • (2011) J Endocrinol , vol.209 , pp. 21-32
    • Powell, W.F.1    Barry, K.J.2    Tulum, I.3
  • 38
    • 33846096308 scopus 로고    scopus 로고
    • Acute renal failure after bilateral nephrectomy is associated with cytokine-mediated pulmonary injury
    • Hoke TS, Douglas IS, Klein CL et al. Acute renal failure after bilateral nephrectomy is associated with cytokine-mediated pulmonary injury. J Am Soc Nephrol 2007; 18: 155-164.
    • (2007) J Am Soc Nephrol , vol.18 , pp. 155-164
    • Hoke, T.S.1    Douglas, I.S.2    Klein, C.L.3
  • 39
    • 84890806413 scopus 로고    scopus 로고
    • FGF-23 and secondary hyperparathyroidism in chronic kidney disease
    • Silver J, Naveh-Many T. FGF-23 and secondary hyperparathyroidism in chronic kidney disease. Nat Rev Nephrol 2013; 9: 641-649.
    • (2013) Nat Rev Nephrol , vol.9 , pp. 641-649
    • Silver, J.1    Naveh-Many, T.2
  • 40
    • 84864750137 scopus 로고    scopus 로고
    • Metabolic acidosis increases fibroblast growth factor 23 in neonatal mouse bone
    • Krieger NS, Culbertson CD, Kyker-Snowman K et al. Metabolic acidosis increases fibroblast growth factor 23 in neonatal mouse bone. Am J Physiol Renal Physiol 2012; 303: F431-F436.
    • (2012) Am J Physiol Renal Physiol , vol.303 , pp. F431-F436
    • Krieger, N.S.1    Culbertson, C.D.2    Kyker-Snowman, K.3
  • 41
    • 26844568409 scopus 로고    scopus 로고
    • Vitamin D receptorindependent FGF23 actions in regulating phosphate and vitamin D metabolism
    • Shimada T, Yamazaki Y, Takahashi M et al. Vitamin D receptorindependent FGF23 actions in regulating phosphate and vitamin D metabolism. Am J Physiol Renal Physiol 2005; 289: F1088-F1095.
    • (2005) Am J Physiol Renal Physiol , vol.289 , pp. F1088-F1095
    • Shimada, T.1    Yamazaki, Y.2    Takahashi, M.3
  • 43
    • 28444486604 scopus 로고    scopus 로고
    • 1alpha,25-dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: The final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport
    • Kolek OI, Hines ER, Jones MD et al. 1alpha,25-dihydroxyvitamin D3 upregulates FGF23 gene expression in bone: the final link in a renal-gastrointestinal-skeletal axis that controls phosphate transport. Am J Physiol Gastrointest Liver Physiol 2005; 289: G1036-G1042.
    • (2005) Am J Physiol Gastrointest Liver Physiol , vol.289 , pp. G1036-G1042
    • Kolek, O.I.1    Hines, E.R.2    Jones, M.D.3
  • 44
    • 81755163635 scopus 로고    scopus 로고
    • Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice
    • Farrow EG, Yu XJ, Summers LJ et al. Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice. Proc Natl Acad Sci USA 2011; 108: E1146-E1155.
    • (2011) Proc Natl Acad Sci USA , vol.108 , pp. E1146-E1155
    • Farrow, E.G.1    Yu, X.J.2    Summers, L.J.3
  • 45
    • 84881241741 scopus 로고    scopus 로고
    • Effects of iron deficiency anemia and its treatment on fibroblast growth factor 23 and phosphate homeostasis in women
    • Wolf M, Koch TA, Bregman DB. Effects of iron deficiency anemia and its treatment on fibroblast growth factor 23 and phosphate homeostasis in women. J Bone Min Res 2013; 28: 1793-1803.
    • (2013) J Bone Min Res , vol.28 , pp. 1793-1803
    • Wolf, M.1    Koch, T.A.2    Bregman, D.B.3
  • 46
    • 84876669460 scopus 로고    scopus 로고
    • 1,25-dihydroxyvitamin D-3 regulation of fibroblast growth factor-23 expression in bone cells: Evidence for primary and secondary mechanisms modulated by leptin and interleukin
    • Saini RK, Kaneko I, Jurutka PW et al. 1,25-dihydroxyvitamin D-3 regulation of fibroblast growth factor-23 expression in bone cells: evidence for primary and secondary mechanisms modulated by leptin and interleukin-Calcif Tissue Int 2013; 92: 339-353.
    • (2013) Calcif Tissue Int , vol.92 , pp. 339-353
    • Saini, R.K.1    Kaneko, I.2    Jurutka, P.W.3
  • 47
    • 80051687775 scopus 로고    scopus 로고
    • Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling
    • Martin A, Liu S, David V et al. Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling. FASEB J 2011; 25: 2551-2562.
    • (2011) FASEB J , vol.25 , pp. 2551-2562
    • Martin, A.1    Liu, S.2    David, V.3
  • 48
    • 0032924124 scopus 로고    scopus 로고
    • Parathyroid hormone regulates the expression of fibroblast growth factor-2 mRNA and fibroblast growth factor receptor mRNA in osteoblastic cells
    • Hurley MM, Tetradis S, Huang YF et al. Parathyroid hormone regulates the expression of fibroblast growth factor-2 mRNA and fibroblast growth factor receptor mRNA in osteoblastic cells. J Bone Min Res 1999; 14: 776-783.
    • (1999) J Bone Min Res , vol.14 , pp. 776-783
    • Hurley, M.M.1    Tetradis, S.2    Huang, Y.F.3
  • 49
    • 78649642147 scopus 로고    scopus 로고
    • Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective
    • Hu MC, Shi MJ, Zhang JN et al. Klotho deficiency is an early biomarker of renal ischemia-reperfusion injury and its replacement is protective. Kidney Int 2010; 78: 1240-1251.
    • (2010) Kidney Int , vol.78 , pp. 1240-1251
    • Hu, M.C.1    Shi, M.J.2    Zhang, J.N.3
  • 50
    • 79960140180 scopus 로고    scopus 로고
    • Java bioinformatics analysis web services for multiple sequence alignment-JABAWS:MSA
    • Troshin PV, Procter JB, Barton GJ. Java bioinformatics analysis web services for multiple sequence alignment-JABAWS:MSA. Bioinformatics 2011; 27: 2001-2002.
    • (2011) Bioinformatics , vol.27 , pp. 2001-2002
    • Troshin, P.V.1    Procter, J.B.2    Barton, G.J.3
  • 51
    • 0028842908 scopus 로고
    • Regulation of the Nur77 orphan steroid-receptor in activation-induced apoptosis
    • Woronicz JD, Lina A, Calnan BJ et al. Regulation of the Nur77 orphan steroid-receptor in activation-induced apoptosis. Mol Cell Biol 1995; 15: 6364-6376.
    • (1995) Mol Cell Biol , vol.15 , pp. 6364-6376
    • Woronicz, J.D.1    Lina, A.2    Calnan, B.J.3
  • 52
    • 38549096565 scopus 로고    scopus 로고
    • JASPAR, the open access database of transcription factor-binding profiles: New content and tools in the 2008 update
    • Bryne JC, Valen E, Tang MHE et al. JASPAR, the open access database of transcription factor-binding profiles: new content and tools in the 2008 update. Nucl Acids Res 2008; 36: D102-D106.
    • (2008) Nucl Acids Res , vol.36 , pp. D102-D106
    • Bryne, J.C.1    Valen, E.2    Tang, M.H.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.