C-terminal tail of FGF19 determines its specificity toward Klotho co-receptors

Journal of Biological Chemistry

Volumn 283, Issue 48, 2008, Pages 33304-33309

  Wu, Xinle ^a   Lemon, Bryan ^a   Li, XiaoFan ^a   Gupte, Jamila ^a   Weiszmann, Jennifer ^a   Stevens, Jennitte ^a   Hawkins, Nessa ^a   Shen, Wenyan ^a   Lindberg, Richard ^a   Chen, Jin Long ^a   Tian, Hui ^a   Li, Yang ^a  

^a AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING ENERGY; BODY FLUIDS; CELL CULTURE; GLUCOSE; PORT TERMINALS;

BILE ACIDS; BINDING SPECIFICITIES; C TERMINUSES; CHIMERIC PROTEINS; FAMILY MEMBERS; FIBROBLAST GROWTH FACTORS; IN VITRO; N TERMINUSES; RELEVANT TARGETS; TRANSMEMBRANE PROTEINS;

PROTEINS;

CHIMERIC PROTEIN; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 19; FIBROBLAST GROWTH FACTOR 21; FIBROBLAST GROWTH FACTOR 23; KLOTHO PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN ALPHA KLOTHO; PROTEIN BETA KLOTHO; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

CELL LINE; FIBROBLAST GROWTH FACTORS; GLUCURONIDASE; HUMANS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 57749105436     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M803319200     Document Type: Article

References (18)

1. Fu, L., John, L. M., Adams, S. H., Yu, X. X., Tomlinson, E., Renz, M., Williams, P. M., Soriano, R., Corpuz, R., Moffat, B., Vandlen, R., Simmons, L., Foster, J., Stephan, J. P., Tsai, S. P., and Stewart, T. A. (2004) Endocrinology 145, 2594-2603
2. Tomlinson, E., Fu, L., John, L., Hultgren, B., Huang, X., Renz, M., Stephan, J. P., Tsai, S. P., Powell-Braxton, L., French, D., and Stewart, T. A. (2002) Endocrinology 143, 1741-1747
3. Kharitonenkov, A., Shiyanova, T. L., Koester, A., Ford, A. M., Micanovic, R., Galbreath, E. J., Sandusky, G. E., Hammond, L. J., Moyers, J. S., Owens, R. A., Gromada, J., Brozinick, J. T., Hawkins, E. D., Wroblewski, V. J., Li, D. S., Mehrbod, F., Jaskunas, S. R., and Shanafelt, A. B. (2005) J. Clin. Investig. 115, 1627-1635
4. Saito, H., Kusano, K., Kinosaki, M., Ito, H., Hirata, M., Segawa, H., Miyamoto, K., and Fukushima, N. (2003) J. Biol. Chem. 278, 2206-2211
5. Inagaki, T., Choi, M., Moschetta, A., Peng, L., Cummins, C. L., McDonald, J. G., Luo, G., Jones, S. A., Goodwin, B., Richardson, J. A., Gerard, R. D., Repa, J. J., Mangelsdorf, D. J., and Kliewer, S. A. (2005) Cell Metab. 2, 217-225
6. Inagaki, T., Dutchak, P., Zhao, G., Ding, X., Gautron, L., Parameswara, V., Li, Y., Goetz, R., Mohammadi, M., Esser, V., Elmquist, J. K., Gerard, R. D., Burgess, S. C., Hammer, R. E., Mangelsdorf, D. J., and Kliewer, S. A. (2007) Cell Metab. 5, 415-425
7. Goetz, R., Beenken, A., Ibrahimi, O. A., Kalinina, J., Olsen, S. K., Eliseenkova, A. V., Xu, C., Neubert, T. A., Zhang, F., Linhardt, R. J., Yu, X., White, K. E., Inagaki, T., Kliewer, S. A., Yamamoto, M., Kurosu, H., Ogawa, Y., Kuro-o, M., Lanske, B., Razzaque, M. S., and Mohammadi, M. (2007) Mol. Cell. Biol. 27, 3417-3428
8. Mohammadi, M., Olsen, S. K., and Ibrahimi, O. A. (2005) Cytokine Growth Factor Rev. 16, 107-137
9. Kurosu, H., Choi, M., Ogawa, Y., Dickson, A. S., Goetz, R., Eliseenkova, A. V., Mohammadi, M., Rosenblatt, K. P., Kliewer, S. A., and Kuro-o, M. (2007) J. Biol. Chem. 282, 26687-26695
10. Kurosu, H., Ogawa, Y., Miyoshi, M., Yamamoto, M., Nandi, A., Rosenblatt, K. P., Baum, M. G., Schiavi, S., Hu, M. C., Moe, O. W., and Kuro-o, M. (2006) J. Biol. Chem. 281, 6120-6123
11. Wu, X., Ge, H., Gupte, J., Weiszmann, J., Shimamoto, G., Stevens, J., Hawkins, N., Lemon, B., Shen, W., Xu, J., Veniant, M. M., Li, Y. S., Lindberg, R., Chen, J. L., Tian, H., and Li, Y. (2007) J. Biol. Chem. 282, 29069-29072
12. Ito, S., Kinoshita, S., Shiraishi, N., Nakagawa, S., Sekine, S., Fujimori, T., and Nabeshima, Y. I. (2000) Mech. Dev. 98, 115-119
13. Tsujikawa, H., Kurotaki, Y., Fujimori, T., Fukuda, K., and Nabeshima, Y. (2003) Mol. Endocrinol. 17, 2393-2403
14. Ogawa, Y., Kurosu, H., Yamamoto, M., Nandi, A., Rosenblatt, K. P., Goetz, R., Eliseenkova, A. V., Mohammadi, M., and Kuro-o, M. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 7432-7437
15. Shimada, T., Kakitani, M., Yamazaki, Y., Hasegawa, H., Takeuchi, Y., Fujita, T., Fukumoto, S., Tomizuka, K., and Yamashita, T. (2004) J. Clin. Investig. 113, 561-568
16. Yoshida, T., Fujimori, T., and Nabeshima, Y. (2002) Endocrinology 143, 683-689
17. Ito, S., Fujimori, T., Furuya, A., Satoh, J., Nabeshima, Y., and Nabeshima, Y. (2005) J. Clin. Investig. 115, 2202-2208
18. Harmer, N. J., Pellegrini, L., Chirgadze, D., Fernandez-Recio, J., and Blundell, T. L. (2004) Biochemistry 43, 629-640