Restoration of leptin responsiveness in diet-induced obese mice using an optimized leptin analog in combination with exendin-4 or FGF21

Journal of Peptide Science

Volumn 18, Issue 6, 2012, Pages 383-393

  Müller, Timo D ^a,b   Sullivan, Lorraine M ^c   Habegger, Kirk ^a   Yi, Chun Xia ^a   Kabra, Dhiraj ^a   Grant, Erin ^a   Ottaway, Nickki ^a   Krishna, Radha ^a   Holland, Jenna ^a   Hembree, Jazzminn ^a   Perez Tilve, Diego ^a   Pfluger, Paul T ^a,b   Deguzman, Michael J ^c   Siladi, Marc E ^c   Kraynov, Vadim S ^c   Axelrod, Douglas W ^c   Dimarchi, Richard ^d   Pinkstaff, Jason K ^c   Tschöp, Matthias H ^a,b  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c AMBRX INC   (United States)

^d INDIANA UNIVERSITY   (United States)

Author keywords

AgRP; DIO; Ex4; FGF21; HFD; Leptin

Indexed keywords

EXENDIN 4; FIBROBLAST GROWTH FACTOR 21; LEPTIN; RECOMBINANT LEPTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CALORIC RESTRICTION; CONTROLLED STUDY; DIET; DRUG DESIGN; DRUG POTENCY; MALE; MONOTHERAPY; MOUSE; NONHUMAN; OBESITY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; WEIGHT REDUCTION;

AGOUTI; MUS; RODENTIA;

EID: 85027936258     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.2408     Document Type: Article

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