Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a myokine

American Journal of Physiology - Endocrinology and Metabolism

Volumn 306, Issue 5, 2014, Pages

  Keipert, Susanne ^a,c   Ost, Mario ^a   Johann, Kornelia ^a   Imber, Francine ^a   Jastroch, Martin ^c   van Schothorst, Evert M ^b   Keijer, Jaap ^b   Klaus, Susanne ^a  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Browning; Energy metabolism; Fibroblast growth factor 21; Myokine; Uncoupling protein 1

Indexed keywords

ANTIMYCIN A1; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; FIBROBLAST GROWTH FACTOR 21; FIBROBLAST GROWTH FACTOR RECEPTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 2; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INITIATION FACTOR 2ALPHA; INSULIN; INTERLEUKIN 6; MESSENGER RNA; MYXOTHIAZOL; PHOSPHOPROTEIN PHOSPHATASE 1; TRIACYLGLYCEROL; UNCOUPLING PROTEIN 1; VASCULOTROPIN B; FIBROBLAST GROWTH FACTOR; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN; MYOKINE; UNCOUPLING PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; BROWN ADIPOSE TISSUE; CELL STRESS; CELL STRUCTURE; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; INSULIN BLOOD LEVEL; LIMIT OF DETECTION; LIPID LIVER LEVEL; MALE; MITOCHONDRIAL RESPIRATION; MOUSE; MUSCLE STRESS; MYOBLAST; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN PHOSPHORYLATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SELECTIVE AUTOPHAGY; SKELETAL MUSCLE; WHITE ADIPOSE TISSUE; ANIMAL; BODY COMPOSITION; BONE DENSITY; BROWNING; CELL LINE; DRUG EFFECT; ENERGY METABOLISM; GENETICS; METABOLISM; MITOCHONDRION; PHOSPHORYLATION; PHYSIOLOGY; TRANSGENIC MOUSE;

BROWNING; ENERGY METABOLISM; FIBROBLAST GROWTH FACTOR 21; MYOKINE; UNCOUPLING PROTEIN 1;

ADIPOSE TISSUE, WHITE; ANIMALS; BODY COMPOSITION; BONE DENSITY; CARBONYL CYANIDE P-TRIFLUOROMETHOXYPHENYLHYDRAZONE; CELL LINE; ENERGY METABOLISM; FIBROBLAST GROWTH FACTORS; ION CHANNELS; MICE; MICE, TRANSGENIC; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MUSCLE, SKELETAL; MYOBLASTS; PHOSPHORYLATION; UNCOUPLING AGENTS;

EID: 84899516860     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00330.2013     Document Type: Article

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