-
1
-
-
84905679771
-
The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue
-
A.C. Adams, C. Yang, T. Coskun, C.C. Cheng, R. Gemeno, Y. Luo, and A. Kharitonenkov The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue Molecular Metabolism 2 2013 31 37
-
(2013)
Molecular Metabolism
, vol.2
, pp. 31-37
-
-
Adams, A.C.1
Yang, C.2
Coskun, T.3
Cheng, C.C.4
Gemeno, R.5
Luo, Y.6
Kharitonenkov, A.7
-
2
-
-
34249711964
-
Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states
-
M.K. Badman, P. Pissios, A.R. Kennedy, G. Koukos, J.S. Flier, and E. Maratos-Flier Hepatic fibroblast growth factor 21 is regulated by PPARalpha and is a key mediator of hepatic lipid metabolism in ketotic states Cell Metab. 5 2007 426 437
-
(2007)
Cell Metab.
, vol.5
, pp. 426-437
-
-
Badman, M.K.1
Pissios, P.2
Kennedy, A.R.3
Koukos, G.4
Flier, J.S.5
Maratos-Flier, E.6
-
3
-
-
0034881391
-
The adipocyte-secreted protein Acrp30 enhances hepatic insulin action
-
A.H. Berg, T.P. Combs, X. Du, M. Brownlee, and P.E. Scherer The adipocyte-secreted protein Acrp30 enhances hepatic insulin action Nat. Med. 7 2001 947 953
-
(2001)
Nat. Med.
, vol.7
, pp. 947-953
-
-
Berg, A.H.1
Combs, T.P.2
Du, X.3
Brownlee, M.4
Scherer, P.E.5
-
4
-
-
69249093921
-
Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity
-
E.D. Berglund, C.Y. Li, H.A. Bina, S.E. Lynes, M.D. Michael, A.B. Shanafelt, A. Kharitonenkov, and D.H. Wasserman Fibroblast growth factor 21 controls glycemia via regulation of hepatic glucose flux and insulin sensitivity Endocrinology 150 2009 4084 4093
-
(2009)
Endocrinology
, vol.150
, pp. 4084-4093
-
-
Berglund, E.D.1
Li, C.Y.2
Bina, H.A.3
Lynes, S.E.4
Michael, M.D.5
Shanafelt, A.B.6
Kharitonenkov, A.7
Wasserman, D.H.8
-
5
-
-
78049279362
-
Adiponectin prevents diabetic premature senescence of endothelial progenitor cells and promotes endothelial repair by suppressing the p38 MAP kinase/p16INK4A signaling pathway
-
J. Chang, Y. Li, Y. Huang, K.S. Lam, R.L. Hoo, W.T. Wong, K.K. Cheng, Y. Wang, P.M. Vanhoutte, and A. Xu Adiponectin prevents diabetic premature senescence of endothelial progenitor cells and promotes endothelial repair by suppressing the p38 MAP kinase/p16INK4A signaling pathway Diabetes 59 2010 2949 2959
-
(2010)
Diabetes
, vol.59
, pp. 2949-2959
-
-
Chang, J.1
Li, Y.2
Huang, Y.3
Lam, K.S.4
Hoo, R.L.5
Wong, W.T.6
Cheng, K.K.7
Wang, Y.8
Vanhoutte, P.M.9
Xu, A.10
-
6
-
-
77955434383
-
Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK-SIRT1-PGC-1alpha pathway
-
M.D. Chau, J. Gao, Q. Yang, Z. Wu, and J. Gromada Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK-SIRT1-PGC-1alpha pathway Proc. Natl. Acad. Sci. USA 107 2010 12553 12558
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 12553-12558
-
-
Chau, M.D.1
Gao, J.2
Yang, Q.3
Wu, Z.4
Gromada, J.5
-
7
-
-
84855473367
-
High plasma level of fibroblast growth factor 21 is an Independent predictor of type 2 diabetes: A 5.4-year population-based prospective study in Chinese subjects
-
C. Chen, B.M. Cheung, A.W. Tso, Y. Wang, L.S. Law, K.L. Ong, N.M. Wat, A. Xu, and K.S. Lam High plasma level of fibroblast growth factor 21 is an Independent predictor of type 2 diabetes: a 5.4-year population-based prospective study in Chinese subjects Diabetes Care 34 2011 2113 2115
-
(2011)
Diabetes Care
, vol.34
, pp. 2113-2115
-
-
Chen, C.1
Cheung, B.M.2
Tso, A.W.3
Wang, Y.4
Law, L.S.5
Ong, K.L.6
Wat, N.M.7
Xu, A.8
Lam, K.S.9
-
8
-
-
80053409251
-
Growth hormone induces hepatic production of fibroblast growth factor 21 through a mechanism dependent on lipolysis in adipocytes
-
W. Chen, R.L. Hoo, M. Konishi, N. Itoh, P.C. Lee, H.Y. Ye, K.S. Lam, and A. Xu Growth hormone induces hepatic production of fibroblast growth factor 21 through a mechanism dependent on lipolysis in adipocytes J. Biol. Chem. 286 2011 34559 34566
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 34559-34566
-
-
Chen, W.1
Hoo, R.L.2
Konishi, M.3
Itoh, N.4
Lee, P.C.5
Ye, H.Y.6
Lam, K.S.7
Xu, A.8
-
9
-
-
57349098220
-
Fibroblast growth factor 21 corrects obesity in mice
-
T. Coskun, H.A. Bina, M.A. Schneider, J.D. Dunbar, C.C. Hu, Y. Chen, D.E. Moller, and A. Kharitonenkov Fibroblast growth factor 21 corrects obesity in mice Endocrinology 149 2008 6018 6027
-
(2008)
Endocrinology
, vol.149
, pp. 6018-6027
-
-
Coskun, T.1
Bina, H.A.2
Schneider, M.A.3
Dunbar, J.D.4
Hu, C.C.5
Chen, Y.6
Moller, D.E.7
Kharitonenkov, A.8
-
10
-
-
84865422329
-
TNF-α represses β-Klotho expression and impairs FGF21 action in adipose cells: Involvement of JNK1 in the FGF21 pathway
-
J. Díaz-Delfín, E. Hondares, R. Iglesias, M. Giralt, C. Caelles, and F. Villarroya TNF-α represses β-Klotho expression and impairs FGF21 action in adipose cells: involvement of JNK1 in the FGF21 pathway Endocrinology 153 2012 4238 4245
-
(2012)
Endocrinology
, vol.153
, pp. 4238-4245
-
-
Díaz-Delfín, J.1
Hondares, E.2
Iglesias, R.3
Giralt, M.4
Caelles, C.5
Villarroya, F.6
-
11
-
-
84865741904
-
βKlotho is required for fibroblast growth factor 21 effects on growth and metabolism
-
X. Ding, J. Boney-Montoya, B.M. Owen, A.L. Bookout, K.C. Coate, D.J. Mangelsdorf, and S.A. Kliewer βKlotho is required for fibroblast growth factor 21 effects on growth and metabolism Cell Metab. 16 2012 387 393
-
(2012)
Cell Metab.
, vol.16
, pp. 387-393
-
-
Ding, X.1
Boney-Montoya, J.2
Owen, B.M.3
Bookout, A.L.4
Coate, K.C.5
Mangelsdorf, D.J.6
Kliewer, S.A.7
-
12
-
-
84863012459
-
Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones
-
P.A. Dutchak, T. Katafuchi, A.L. Bookout, J.H. Choi, R.T. Yu, D.J. Mangelsdorf, and S.A. Kliewer Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones Cell 148 2012 556 567
-
(2012)
Cell
, vol.148
, pp. 556-567
-
-
Dutchak, P.A.1
Katafuchi, T.2
Bookout, A.L.3
Choi, J.H.4
Yu, R.T.5
Mangelsdorf, D.J.6
Kliewer, S.A.7
-
13
-
-
0037459090
-
Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes
-
M. Fasshauer, S. Kralisch, M. Klier, U. Lossner, M. Bluher, J. Klein, and R. Paschke Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes Biochem. Biophys. Res. Commun. 301 2003 1045 1050
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.301
, pp. 1045-1050
-
-
Fasshauer, M.1
Kralisch, S.2
Klier, M.3
Lossner, U.4
Bluher, M.5
Klein, J.6
Paschke, R.7
-
14
-
-
78049297991
-
Obesity is a fibroblast growth factor 21 (FGF21)-resistant state
-
F.M. Fisher, P.C. Chui, P.J. Antonellis, H.A. Bina, A. Kharitonenkov, J.S. Flier, and E. Maratos-Flier Obesity is a fibroblast growth factor 21 (FGF21)-resistant state Diabetes 59 2010 2781 2789
-
(2010)
Diabetes
, vol.59
, pp. 2781-2789
-
-
Fisher, F.M.1
Chui, P.C.2
Antonellis, P.J.3
Bina, H.A.4
Kharitonenkov, A.5
Flier, J.S.6
Maratos-Flier, E.7
-
15
-
-
79960726293
-
Integrated regulation of hepatic metabolism by fibroblast growth factor 21 (FGF21) in vivo
-
F.M. Fisher, J.L. Estall, A.C. Adams, P.J. Antonellis, H.A. Bina, J.S. Flier, A. Kharitonenkov, B.M. Spiegelman, and E. Maratos-Flier Integrated regulation of hepatic metabolism by fibroblast growth factor 21 (FGF21) in vivo Endocrinology 152 2011 2996 3004
-
(2011)
Endocrinology
, vol.152
, pp. 2996-3004
-
-
Fisher, F.M.1
Estall, J.L.2
Adams, A.C.3
Antonellis, P.J.4
Bina, H.A.5
Flier, J.S.6
Kharitonenkov, A.7
Spiegelman, B.M.8
Maratos-Flier, E.9
-
16
-
-
80053428117
-
Fibroblast growth factor 21 induces glucose transporter-1 expression through activation of the serum response factor/Ets-like protein-1 in adipocytes
-
X. Ge, C. Chen, X. Hui, Y. Wang, K.S. Lam, and A. Xu Fibroblast growth factor 21 induces glucose transporter-1 expression through activation of the serum response factor/Ets-like protein-1 in adipocytes J. Biol. Chem. 286 2011 34533 34541
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 34533-34541
-
-
Ge, X.1
Chen, C.2
Hui, X.3
Wang, Y.4
Lam, K.S.5
Xu, A.6
-
17
-
-
79953886306
-
Thermogenic activation induces FGF21 expression and release in brown adipose tissue
-
E. Hondares, R. Iglesias, A. Giralt, F.J. Gonzalez, M. Giralt, T. Mampel, and F. Villarroya Thermogenic activation induces FGF21 expression and release in brown adipose tissue J. Biol. Chem. 286 2011 12983 12990
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 12983-12990
-
-
Hondares, E.1
Iglesias, R.2
Giralt, A.3
Gonzalez, F.J.4
Giralt, M.5
Mampel, T.6
Villarroya, F.7
-
18
-
-
70349324370
-
Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver
-
Y. Hotta, H. Nakamura, M. Konishi, Y. Murata, H. Takagi, S. Matsumura, K. Inoue, T. Fushiki, and N. Itoh Fibroblast growth factor 21 regulates lipolysis in white adipose tissue but is not required for ketogenesis and triglyceride clearance in liver Endocrinology 150 2009 4625 4633
-
(2009)
Endocrinology
, vol.150
, pp. 4625-4633
-
-
Hotta, Y.1
Nakamura, H.2
Konishi, M.3
Murata, Y.4
Takagi, H.5
Matsumura, S.6
Inoue, K.7
Fushiki, T.8
Itoh, N.9
-
19
-
-
34249686631
-
Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21
-
T. Inagaki, P. Dutchak, G. Zhao, X. Ding, L. Gautron, V. Parameswara, Y. Li, R. Goetz, M. Mohammadi, and V. Esser Endocrine regulation of the fasting response by PPARalpha-mediated induction of fibroblast growth factor 21 Cell Metab. 5 2007 415 425
-
(2007)
Cell Metab.
, vol.5
, pp. 415-425
-
-
Inagaki, T.1
Dutchak, P.2
Zhao, G.3
Ding, X.4
Gautron, L.5
Parameswara, V.6
Li, Y.7
Goetz, R.8
Mohammadi, M.9
Esser, V.10
-
20
-
-
0037677767
-
Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors
-
M. Iwaki, M. Matsuda, N. Maeda, T. Funahashi, Y. Matsuzawa, M. Makishima, and I. Shimomura Induction of adiponectin, a fat-derived antidiabetic and antiatherogenic factor, by nuclear receptors Diabetes 52 2003 1655 1663
-
(2003)
Diabetes
, vol.52
, pp. 1655-1663
-
-
Iwaki, M.1
Matsuda, M.2
Maeda, N.3
Funahashi, T.4
Matsuzawa, Y.5
Makishima, M.6
Shimomura, I.7
-
21
-
-
33745834319
-
Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome
-
T. Kadowaki, T. Yamauchi, N. Kubota, K. Hara, K. Ueki, and K. Tobe Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome J. Clin. Invest. 116 2006 1784 1792
-
(2006)
J. Clin. Invest.
, vol.116
, pp. 1784-1792
-
-
Kadowaki, T.1
Yamauchi, T.2
Kubota, N.3
Hara, K.4
Ueki, K.5
Tobe, K.6
-
22
-
-
20444435873
-
FGF-21 as a novel metabolic regulator
-
A. Kharitonenkov, T.L. Shiyanova, A. Koester, A.M. Ford, R. Micanovic, E.J. Galbreath, G.E. Sandusky, L.J. Hammond, J.S. Moyers, and R.A. Owens FGF-21 as a novel metabolic regulator J. Clin. Invest. 115 2005 1627 1635
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1627-1635
-
-
Kharitonenkov, A.1
Shiyanova, T.L.2
Koester, A.3
Ford, A.M.4
Micanovic, R.5
Galbreath, E.J.6
Sandusky, G.E.7
Hammond, L.J.8
Moyers, J.S.9
Owens, R.A.10
-
23
-
-
33846418834
-
The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21
-
A. Kharitonenkov, V.J. Wroblewski, A. Koester, Y.F. Chen, C.K. Clutinger, X.T. Tigno, B.C. Hansen, A.B. Shanafelt, and G.J. Etgen The metabolic state of diabetic monkeys is regulated by fibroblast growth factor-21 Endocrinology 148 2007 774 781
-
(2007)
Endocrinology
, vol.148
, pp. 774-781
-
-
Kharitonenkov, A.1
Wroblewski, V.J.2
Koester, A.3
Chen, Y.F.4
Clutinger, C.K.5
Tigno, X.T.6
Hansen, B.C.7
Shanafelt, A.B.8
Etgen, G.J.9
-
24
-
-
39149091423
-
FGF-21/FGF-21 receptor interaction and activation is determined by betaKlotho
-
A. Kharitonenkov, J.D. Dunbar, H.A. Bina, S. Bright, J.S. Moyers, C. Zhang, L. Ding, R. Micanovic, S.F. Mehrbod, and M.D. Knierman FGF-21/FGF-21 receptor interaction and activation is determined by betaKlotho J. Cell. Physiol. 215 2008 1 7
-
(2008)
J. Cell. Physiol.
, vol.215
, pp. 1-7
-
-
Kharitonenkov, A.1
Dunbar, J.D.2
Bina, H.A.3
Bright, S.4
Moyers, J.S.5
Zhang, C.6
Ding, L.7
Micanovic, R.8
Mehrbod, S.F.9
Knierman, M.D.10
-
25
-
-
34848872799
-
Obesity-associated improvements in metabolic profile through expansion of adipose tissue
-
J.Y. Kim, E. van de Wall, M. Laplante, A. Azzara, M.E. Trujillo, S.M. Hofmann, T. Schraw, J.L. Durand, H. Li, and G. Li Obesity-associated improvements in metabolic profile through expansion of adipose tissue J. Clin. Invest. 117 2007 2621 2637
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 2621-2637
-
-
Kim, J.Y.1
Van De Wall, E.2
Laplante, M.3
Azzara, A.4
Trujillo, M.E.5
Hofmann, S.M.6
Schraw, T.7
Durand, J.L.8
Li, H.9
Li, G.10
-
26
-
-
33646852805
-
Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways
-
N. Kubota, Y. Terauchi, T. Kubota, H. Kumagai, S. Itoh, H. Satoh, W. Yano, H. Ogata, K. Tokuyama, and I. Takamoto Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways J. Biol. Chem. 281 2006 8748 8755
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 8748-8755
-
-
Kubota, N.1
Terauchi, Y.2
Kubota, T.3
Kumagai, H.4
Itoh, S.5
Satoh, H.6
Yano, W.7
Ogata, H.8
Tokuyama, K.9
Takamoto, I.10
-
27
-
-
82255173963
-
Hypoadiponectinemia predicts impaired endothelium-independent vasodilation in newly diagnosed type 2 diabetic patients: An 8-year prospective study
-
H. Li, Y. Xiao, H. Liu, X.Y. Chen, X.Y. Li, W.L. Tang, S.P. Liu, A.M. Xu, and Z.G. Zhou Hypoadiponectinemia predicts impaired endothelium-independent vasodilation in newly diagnosed type 2 diabetic patients: an 8-year prospective study Chin. Med. J. (Engl.) 124 2011 3607 3612
-
(2011)
Chin. Med. J. (Engl.)
, vol.124
, pp. 3607-3612
-
-
Li, H.1
Xiao, Y.2
Liu, H.3
Chen, X.Y.4
Li, X.Y.5
Tang, W.L.6
Liu, S.P.7
Xu, A.M.8
Zhou, Z.G.9
-
28
-
-
84859529243
-
Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3
-
H. Li, Z. Gao, J. Zhang, X. Ye, A. Xu, J. Ye, and W. Jia Sodium butyrate stimulates expression of fibroblast growth factor 21 in liver by inhibition of histone deacetylase 3 Diabetes 61 2012 797 806
-
(2012)
Diabetes
, vol.61
, pp. 797-806
-
-
Li, H.1
Gao, Z.2
Zhang, J.3
Ye, X.4
Xu, A.5
Ye, J.6
Jia, W.7
-
29
-
-
0037031088
-
Adiponectin and development of type 2 diabetes in the Pima Indian population
-
R.S. Lindsay, T. Funahashi, R.L. Hanson, Y. Matsuzawa, S. Tanaka, P.A. Tataranni, W.C. Knowler, and J. Krakoff Adiponectin and development of type 2 diabetes in the Pima Indian population Lancet 360 2002 57 58
-
(2002)
Lancet
, vol.360
, pp. 57-58
-
-
Lindsay, R.S.1
Funahashi, T.2
Hanson, R.L.3
Matsuzawa, Y.4
Tanaka, S.5
Tataranni, P.A.6
Knowler, W.C.7
Krakoff, J.8
-
30
-
-
72449141637
-
Transcriptional and post-translational regulation of adiponectin
-
M. Liu, and F. Liu Transcriptional and post-translational regulation of adiponectin Biochem. J. 425 2010 41 52
-
(2010)
Biochem. J.
, vol.425
, pp. 41-52
-
-
Liu, M.1
Liu, F.2
-
31
-
-
57449111690
-
A disulfide-bond A oxidoreductase-like protein (DsbA-L) regulates adiponectin multimerization
-
M. Liu, L. Zhou, A. Xu, K.S. Lam, M.D. Wetzel, R. Xiang, J. Zhang, X. Xin, L.Q. Dong, and F. Liu A disulfide-bond A oxidoreductase-like protein (DsbA-L) regulates adiponectin multimerization Proc. Natl. Acad. Sci. USA 105 2008 18302 18307
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 18302-18307
-
-
Liu, M.1
Zhou, L.2
Xu, A.3
Lam, K.S.4
Wetzel, M.D.5
Xiang, R.6
Zhang, J.7
Xin, X.8
Dong, L.Q.9
Liu, F.10
-
32
-
-
0037144394
-
Increased beta -oxidation but no insulin resistance or glucose intolerance in mice lacking adiponectin
-
K. Ma, A. Cabrero, P.K. Saha, H. Kojima, L. Li, B.H. Chang, A. Paul, and L. Chan Increased beta -oxidation but no insulin resistance or glucose intolerance in mice lacking adiponectin J. Biol. Chem. 277 2002 34658 34661
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 34658-34661
-
-
Ma, K.1
Cabrero, A.2
Saha, P.K.3
Kojima, H.4
Li, L.5
Chang, B.H.6
Paul, A.7
Chan, L.8
-
33
-
-
33646346627
-
Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists
-
A.R. Nawrocki, M.W. Rajala, E. Tomas, U.B. Pajvani, A.K. Saha, M.E. Trumbauer, Z. Pang, A.S. Chen, N.B. Ruderman, and H. Chen Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists J. Biol. Chem. 281 2006 2654 2660
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 2654-2660
-
-
Nawrocki, A.R.1
Rajala, M.W.2
Tomas, E.3
Pajvani, U.B.4
Saha, A.K.5
Trumbauer, M.E.6
Pang, Z.7
Chen, A.S.8
Ruderman, N.B.9
Chen, H.10
-
34
-
-
67649823642
-
FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response
-
M.J. Potthoff, T. Inagaki, S. Satapati, X. Ding, T. He, R. Goetz, M. Mohammadi, B.N. Finck, D.J. Mangelsdorf, S.A. Kliewer, and S.C. Burgess FGF21 induces PGC-1alpha and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response Proc. Natl. Acad. Sci. USA 106 2009 10853 10858
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 10853-10858
-
-
Potthoff, M.J.1
Inagaki, T.2
Satapati, S.3
Ding, X.4
He, T.5
Goetz, R.6
Mohammadi, M.7
Finck, B.N.8
Mangelsdorf, D.J.9
Kliewer, S.A.10
Burgess, S.C.11
-
35
-
-
84857185764
-
Endocrine fibroblast growth factors 15/19 and 21: From feast to famine
-
M.J. Potthoff, S.A. Kliewer, and D.J. Mangelsdorf Endocrine fibroblast growth factors 15/19 and 21: from feast to famine Genes Dev. 26 2012 312 324
-
(2012)
Genes Dev.
, vol.26
, pp. 312-324
-
-
Potthoff, M.J.1
Kliewer, S.A.2
Mangelsdorf, D.J.3
-
36
-
-
41649109108
-
BetaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c
-
M. Suzuki, Y. Uehara, K. Motomura-Matsuzaka, J. Oki, Y. Koyama, M. Kimura, M. Asada, A. Komi-Kuramochi, S. Oka, and T. Imamura betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c Mol. Endocrinol. 22 2008 1006 1014
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 1006-1014
-
-
Suzuki, M.1
Uehara, Y.2
Motomura-Matsuzaka, K.3
Oki, J.4
Koyama, Y.5
Kimura, M.6
Asada, M.7
Komi-Kuramochi, A.8
Oka, S.9
Imamura, T.10
-
37
-
-
84863637593
-
FGF21 promotes metabolic homeostasis via white adipose and leptin in mice
-
M.M. Véniant, C. Hale, J. Helmering, M.M. Chen, S. Stanislaus, J. Busby, S. Vonderfecht, J. Xu, and D.J. Lloyd FGF21 promotes metabolic homeostasis via white adipose and leptin in mice PLoS ONE 7 2012 e40164
-
(2012)
PLoS ONE
, vol.7
, pp. 40164
-
-
Véniant, M.M.1
Hale, C.2
Helmering, J.3
Chen, M.M.4
Stanislaus, S.5
Busby, J.6
Vonderfecht, S.7
Xu, J.8
Lloyd, D.J.9
-
38
-
-
33745222085
-
Post-translational modifications of the four conserved lysine residues within the collagenous domain of adiponectin are required for the formation of its high molecular weight oligomeric complex
-
Y. Wang, K.S. Lam, L. Chan, K.W. Chan, J.B. Lam, M.C. Lam, R.C. Hoo, W.W. Mak, G.J. Cooper, and A. Xu Post-translational modifications of the four conserved lysine residues within the collagenous domain of adiponectin are required for the formation of its high molecular weight oligomeric complex J. Biol. Chem. 281 2006 16391 16400
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 16391-16400
-
-
Wang, Y.1
Lam, K.S.2
Chan, L.3
Chan, K.W.4
Lam, J.B.5
Lam, M.C.6
Hoo, R.C.7
Mak, W.W.8
Cooper, G.J.9
Xu, A.10
-
39
-
-
34248197560
-
Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention
-
Z.V. Wang, T.D. Schraw, J.Y. Kim, T. Khan, M.W. Rajala, A. Follenzi, and P.E. Scherer Secretion of the adipocyte-specific secretory protein adiponectin critically depends on thiol-mediated protein retention Mol. Cell. Biol. 27 2007 3716 3731
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 3716-3731
-
-
Wang, Z.V.1
Schraw, T.D.2
Kim, J.Y.3
Khan, T.4
Rajala, M.W.5
Follenzi, A.6
Scherer, P.E.7
-
40
-
-
38949125405
-
Post-translational modifications of adiponectin: Mechanisms and functional implications
-
Y. Wang, K.S. Lam, M.H. Yau, and A. Xu Post-translational modifications of adiponectin: mechanisms and functional implications Biochem. J. 409 2008 623 633
-
(2008)
Biochem. J.
, vol.409
, pp. 623-633
-
-
Wang, Y.1
Lam, K.S.2
Yau, M.H.3
Xu, A.4
-
41
-
-
0034999667
-
Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia
-
C. Weyer, T. Funahashi, S. Tanaka, K. Hotta, Y. Matsuzawa, R.E. Pratley, and P.A. Tataranni Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia J. Clin. Endocrinol. Metab. 86 2001 1930 1935
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 1930-1935
-
-
Weyer, C.1
Funahashi, T.2
Tanaka, S.3
Hotta, K.4
Matsuzawa, Y.5
Pratley, R.E.6
Tataranni, P.A.7
-
42
-
-
0041302377
-
The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice
-
A. Xu, Y. Wang, H. Keshaw, L.Y. Xu, K.S. Lam, and G.J. Cooper The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice J. Clin. Invest. 112 2003 91 100
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 91-100
-
-
Xu, A.1
Wang, Y.2
Keshaw, H.3
Xu, L.Y.4
Lam, K.S.5
Cooper, G.J.6
-
43
-
-
24044479055
-
Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes
-
A. Xu, K.W. Chan, R.L. Hoo, Y. Wang, K.C. Tan, J. Zhang, B. Chen, M.C. Lam, C. Tse, G.J. Cooper, and K.S. Lam Testosterone selectively reduces the high molecular weight form of adiponectin by inhibiting its secretion from adipocytes J. Biol. Chem. 280 2005 18073 18080
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 18073-18080
-
-
Xu, A.1
Chan, K.W.2
Hoo, R.L.3
Wang, Y.4
Tan, K.C.5
Zhang, J.6
Chen, B.7
Lam, M.C.8
Tse, C.9
Cooper, G.J.10
Lam, K.S.11
-
44
-
-
59649117072
-
Selective elevation of adiponectin production by the natural compounds derived from a medicinal herb alleviates insulin resistance and glucose intolerance in obese mice
-
A. Xu, H. Wang, R.L. Hoo, G. Sweeney, P.M. Vanhoutte, Y. Wang, D. Wu, W. Chu, G. Qin, and K.S. Lam Selective elevation of adiponectin production by the natural compounds derived from a medicinal herb alleviates insulin resistance and glucose intolerance in obese mice Endocrinology 150 2009 625 633
-
(2009)
Endocrinology
, vol.150
, pp. 625-633
-
-
Xu, A.1
Wang, H.2
Hoo, R.L.3
Sweeney, G.4
Vanhoutte, P.M.5
Wang, Y.6
Wu, D.7
Chu, W.8
Qin, G.9
Lam, K.S.10
-
45
-
-
61649127208
-
Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice
-
J. Xu, D.J. Lloyd, C. Hale, S. Stanislaus, M. Chen, G. Sivits, S. Vonderfecht, R. Hecht, Y.S. Li, and R.A. Lindberg Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice Diabetes 58 2009 250 259
-
(2009)
Diabetes
, vol.58
, pp. 250-259
-
-
Xu, J.1
Lloyd, D.J.2
Hale, C.3
Stanislaus, S.4
Chen, M.5
Sivits, G.6
Vonderfecht, S.7
Hecht, R.8
Li, Y.S.9
Lindberg, R.A.10
-
46
-
-
17944365228
-
The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity
-
T. Yamauchi, J. Kamon, H. Waki, Y. Terauchi, N. Kubota, K. Hara, Y. Mori, T. Ide, K. Murakami, and N. Tsuboyama-Kasaoka The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity Nat. Med. 7 2001 941 946
-
(2001)
Nat. Med.
, vol.7
, pp. 941-946
-
-
Yamauchi, T.1
Kamon, J.2
Waki, H.3
Terauchi, Y.4
Kubota, N.5
Hara, K.6
Mori, Y.7
Ide, T.8
Murakami, K.9
Tsuboyama-Kasaoka, N.10
-
47
-
-
84863338708
-
Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB
-
C. Yang, C. Jin, X. Li, F. Wang, W.L. McKeehan, and Y. Luo Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB PLoS ONE 7 2012 e33870
-
(2012)
PLoS ONE
, vol.7
, pp. 33870
-
-
Yang, C.1
Jin, C.2
Li, X.3
Wang, F.4
McKeehan, W.L.5
Luo, Y.6
-
48
-
-
79956113302
-
Circadian rhythm of circulating fibroblast growth factor 21 is related to diurnal changes in fatty acids in humans
-
H. Yu, F. Xia, K.S. Lam, Y. Wang, Y. Bao, J. Zhang, Y. Gu, P. Zhou, J. Lu, W. Jia, and A. Xu Circadian rhythm of circulating fibroblast growth factor 21 is related to diurnal changes in fatty acids in humans Clin. Chem. 57 2011 691 700
-
(2011)
Clin. Chem.
, vol.57
, pp. 691-700
-
-
Yu, H.1
Xia, F.2
Lam, K.S.3
Wang, Y.4
Bao, Y.5
Zhang, J.6
Gu, Y.7
Zhou, P.8
Lu, J.9
Jia, W.10
Xu, A.11
-
49
-
-
48349146527
-
Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans
-
X. Zhang, D.C. Yeung, M. Karpisek, D. Stejskal, Z.G. Zhou, F. Liu, R.L. Wong, W.S. Chow, A.W. Tso, K.S. Lam, and A. Xu Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans Diabetes 57 2008 1246 1253
-
(2008)
Diabetes
, vol.57
, pp. 1246-1253
-
-
Zhang, X.1
Yeung, D.C.2
Karpisek, M.3
Stejskal, D.4
Zhou, Z.G.5
Liu, F.6
Wong, R.L.7
Chow, W.S.8
Tso, A.W.9
Lam, K.S.10
Xu, A.11
-
50
-
-
54449085766
-
Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury
-
M. Zhou, A. Xu, P.K. Tam, K.S. Lam, L. Chan, R.L. Hoo, J. Liu, K.H. Chow, and Y. Wang Mitochondrial dysfunction contributes to the increased vulnerabilities of adiponectin knockout mice to liver injury Hepatology 48 2008 1087 1096
-
(2008)
Hepatology
, vol.48
, pp. 1087-1096
-
-
Zhou, M.1
Xu, A.2
Tam, P.K.3
Lam, K.S.4
Chan, L.5
Hoo, R.L.6
Liu, J.7
Chow, K.H.8
Wang, Y.9
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