The starvation hormone, fibroblast growth factor-21, extends lifespan in mice

eLife

Volumn 2012, Issue 1, 2012, Pages

  Zhang, Yuan ^a   Xie, Yang ^b   Berglund, Eric D ^b   Colbert Coate, Katie ^a   He, Tian Teng ^b   Katafuchi, Takeshi ^a   Xiao, Guanghua ^b   Potthoff, Matthew J ^a   Wei, Wei ^a   Wan, Yihong ^a   Yu, Ruth T ^c   Evans, Ronald M ^c   Kliewer, Steven A ^a   Mangelsdorf, David J ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; ADIPONECTIN; CHOLESTEROL; FIBROBLAST GROWTH FACTOR 21; GLUCOSE; INSULIN; KETONE BODY; LEPTIN; TRIACYLGLYCEROL; FATTY ACID; FIBROBLAST GROWTH FACTOR; GROWTH HORMONE; INSULIN-LIKE GROWTH FACTOR-1, MOUSE; MTOR PROTEIN, MOUSE; NICOTINAMIDE ADENINE DINUCLEOTIDE; SOMATOMEDIN C; TARGET OF RAPAMYCIN KINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY COMPOSITION; BODY WEIGHT; CALORIC RESTRICTION; CONTROLLED STUDY; FEMALE; FOOD INTAKE; GASTROCNEMIUS MUSCLE; GENE CONTROL; GLUCOSE HOMEOSTASIS; GLUCOSE TOLERANCE TEST; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; LIFESPAN; LIPID COMPOSITION; MALE; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXYGEN CONSUMPTION; SIGNAL TRANSDUCTION; STARVATION; WESTERN BLOTTING; ADAPTATION; ANIMAL; DIET RESTRICTION; GENE EXPRESSION REGULATION; GENETICS; INSULIN RESISTANCE; LIPID METABOLISM; LIVER; LONGEVITY; METABOLISM; OSTEOLYSIS; OXIDATION REDUCTION REACTION; TRANSGENE; TRANSGENIC MOUSE;

ADAPTATION, PHYSIOLOGICAL; ADENYLATE KINASE; ANIMALS; BONE RESORPTION; CALORIC RESTRICTION; FASTING; FATTY ACIDS; FEMALE; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION; GROWTH HORMONE; INSULIN RESISTANCE; INSULIN-LIKE GROWTH FACTOR I; KETONE BODIES; LIPID METABOLISM; LIVER; LONGEVITY; MALE; MICE; MICE, TRANSGENIC; NAD; OXIDATION-REDUCTION; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES; TRANSGENES;

EID: 84881508008     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.00065     Document Type: Article

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