Fibroblast growth factor-19, a novel factor that inhibits hepatic fatty acid synthesis

Journal of Biological Chemistry

Volumn 284, Issue 15, 2009, Pages 10023-10033

  Bhatnagar, Sushant ^a   Dammron, Holly A ^a   Hillgartner, F Bradley ^a  

^a WEST VIRGINIA UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOSE TISSUE; AMP-ACTIVATED PROTEIN KINASE; ANIMAL MODEL; BENEFICIAL EFFECTS; COACTIVATOR; FATTY ACID SYNTHESIS; FIBROBLAST GROWTH FACTOR; GENE TRANSCRIPTIONS; GLUCOSE TOLERANCE; HEPATIC STEATOSIS; HEPATOCYTE CULTURE; HETERODIMER; HYPERLIPIDEMIA; INHIBITORY EFFECT; KEY PROCESS; LIPOGENESIS; LIPOGENIC ENZYMES; METABOLIC SYNDROMES; P38 MAPK; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; SIGNAL TRANSDUCTION PATHWAYS; STEROL REGULATORY ELEMENT-BINDING PROTEINS; TRANSCRIPTIONAL ACTIVATORS; TRANSCRIPTIONAL REPRESSORS; TRIACYLGLYCEROL;

ACIDS; BIOACTIVITY; CELL CULTURE; CHEMICAL ACTIVATION; ENZYME ACTIVITY; ENZYMES; FATTY ACIDS; FIBROBLASTS; GLUCOSE; GLYCEROL; INSULIN; MEDICAL PROBLEMS; PEPTIDES; SIGNAL TRANSDUCTION; TRANSCRIPTION;

ENZYME INHIBITION;

BOVINE INSULIN; FATTY ACID; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 19; GLUCOSE; HETERODIMER; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; STAT3 PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; CHOLESTEROL 7ALPHA MONOOXYGENASE; CYP7A1 PROTEIN, RAT; FGF19 PROTEIN, HUMAN; FGF19 PROTEIN, RAT; INSULIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG DETERMINATION; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FATTY ACID SYNTHESIS; GLUCOSE TOLERANCE; HORMONAL REGULATION; HUMAN; HUMAN CELL; LIPOGENESIS; LIVER CELL CULTURE; MALE; METABOLIC SYNDROME X; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS INHIBITION; RAT; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANIMAL; BIOLOGICAL MODEL; CELL LINE; DIMERIZATION; LIVER; LIVER CELL; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TUMOR CELL LINE;

ANIMALIA;

ANIMALS; CELL LINE; CELL LINE, TUMOR; CHOLESTEROL 7-ALPHA-HYDROXYLASE; DIMERIZATION; FATTY ACIDS; FIBROBLAST GROWTH FACTORS; HEPATOCYTES; HUMANS; INSULIN; LIVER; MODELS, BIOLOGICAL; RATS; RATS, SPRAGUE-DAWLEY; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 65649152582     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M808818200     Document Type: Article

References (66)

1. Muoio, D. M., and Newgard, C. B. (2008) Nat. Rev. Mol. Cell Biol. 9, 193-205
2. Postic, C., and Girard, J. (2008) J. Clin. Investig. 118, 829-838
3. Savage, D. B., Petersen, K. F., and Shulman, G. I. (2007) Physiol. Rev. 87, 507-520
4. Zhou, G., Myers, R., Li, Y., Chen, Y., Shen, X., Fenyk-Melody, J., Wu, M., Ventre, J., Doebber, T., Fujii, N., Musi, N., Hirshman, M. F., Goodyear, L. J., and Moller, D. E. (2001) J. Clin. Investig. 108, 1167-1174
5. Ladher, R. K., Anakwe, K. U., Gurney, A. L., Schoenwolf, G. C., and Francis-West, P. H. (2000) Science 290, 1965-1967
6. Inagaki, T., Choi, M., Moschetta, A., Peng, L., Cummins, C. L., McDonald, J. G., Luo, G., Jones, S. A., Goodwin, B., Richardson, J. A., Gerard, R. D., Repa, J. J., Mangelsdorf, D. J., and Kliewer, S. A. (2005) Cell Metab. 2, 217-225
7. Holt, J. A., Luo, G., Billin, A. N., Bisi, J., McNeill, Y. Y., Kozarsky, K. F., Donahee, M., Wang, D. Y., Mansfield, T. A., Kliewer, S. A., Goodwin, B., and Jones, S. A. (2003) Genes Dev. 17, 1581-1591
8. Fu, L., John, L. M., Adams, S. H., Yu, X. X., Tomlinson, E., Renz, M., Williams, P. M., Soriano, R., Corpuz, R., Moffat, B., Vandlen, R., Simmons, L., Foster, J., Stephan, J. P., Tsai, S. P., and Stewart, T. A. (2004) Endocrinology 145, 2594-2603
9. Tomlinson, E., Fu, L., John, L., Hultgren, B., Huang, X., Renz, M., Stephan, J. P., Tsai, S. P., Powell-Braxton, L., French, D., and Stewart, T. A. (2002) Endocrinology 143, 1741-1747
10. Stabile, L. P., Klautky, S. A., Minor, S. M., and Salati, L. M. (1998) J. Lipid Res. 39, 1951-1963
11. Lowenstein, J. M., Brunengraber, H., and Wadke, M. (1975) Methods Enzymol. 35, 279-287
12. Chomczynski, P., and Sacchi, N. (1987) Anal. Biochem. 162, 156-159
13. Hansmannel, F., Mordier, S., and Iynedjian, P. B. (2006) Biochem. J. 399, 275-283
14. Standaert, M. L., Galloway, L., Karnam, P., Bandyopadhyay, G., Moscat, J., and Farese, R. V. (1997) J. Biol. Chem. 272, 30075-30082
15. Hillgartner, F. B., Salati, L. M., and Goodridge, A. G. (1995) Physiol. Rev. 75, 47-76
16. Saggerson, D. (2008) Annu. Rev. Nutr. 28, 253-272
17. Postic, C., Dentin, R., Denechaud, P. D., and Girard, J. (2007) Annu. Rev. Nutr. 27, 179-192
18. Dentin, R., Pegorier, J. P., Benhamed, F., Foufelle, F., Ferre, P., Fauveau, V., Magnuson, M. A., Girard, J., and Postic, C. (2004) J. Biol. Chem. 279, 20314-20326
19. Koo, S. H., Dutcher, A. K., and Towle, H. C. (2001) J. Biol. Chem. 276, 9437-9445
20. Edwards, P. A., Kennedy, M. A., and Mak, P. A. (2002) Vascul. Pharmacol. 38, 249-256
21. Repa, J. J., and Mangelsdorf, D. J. (2002) Nat. Med. 8, 1243-1248
22. Joseph, S. B., Laffitte, B. A., Patel, P. H., Watson, M. A., Matsukuma, K. E., Walczak, R., Collins, J. L., Osborne, T. F., and Tontonoz, P. (2002) J. Biol. Chem. 277, 11019-11025
23. Talukdar, S., and Hillgartner, F. B. (2006) J. Lipid Res. 47, 2451-2461
24. Tobin, K. A., Ulven, S. M., Schuster, G. U., Steineger, H. H., Andresen, S. M., Gustafsson, J. A., and Nebb, H. I. (2002) J. Biol. Chem. 277, 10691-10697
25. Narkewicz, M. R., Iynedjian, P. B., Ferre, P., and Girard, J. (1990) Biochem. J. 271, 585-589
26. Petty, K. J., Morioka, H., Mitsuhashi, T., and Nikodem, V. M. (1989) J. Biol. Chem. 264, 11483-11490
27. Zilz, N. D., Murray, M. B., and Towle, H. C. (1990) J. Biol. Chem. 265, 8136-8143
28. Foufelle, F., and Ferre, P. (2002) Biochem. J. 366, 377-391
29. Gregori, C., Guillet-Deniau, I., Girard, J., Decaux, J. F., and Pichard, A. L. (2006) FEBS Lett. 580, 410-414
30. Stoeckman, A. K., and Towle, H. C. (2002) J. Biol. Chem. 277, 27029-27035
31. Cagen, L. M., Deng, X., Wilcox, H. G., Park, E. A., Raghow, R., and Elam, M. B. (2005) Biochem. J. 385, 207-216
32. Chen, G., Liang, G., Ou, J., Goldstein, J. L., and Brown, M. S. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 11245-11250
33. Taniguchi, C. M., Emanuelli, B., and Kahn, C. R. (2006) Nat. Rev. Mol. Cell Biol. 7, 85-96
34. Fleischmann, M., and Iynedjian, P. B. (2000) Biochem. J. 349, 13-17
35. Iynedjian, P. B., Roth, R. A., Fleischmann, M., and Gjinovci, A. (2000) Biochem. J. 351, 621-627
36. Matsumoto, M., Ogawa, W., Akimoto, K., Inoue, H., Miyake, K., Furukawa, K., Hayashi, Y., Iguchi, H., Matsuki, Y., Hiramatsu, R., Shimano, H., Yamada, N., Ohno, S., Kasuga, M., and Noda, T. (2003) J. Clin. Investig. 112, 935-944
37. Ono, H., Shimano, H., Katagiri, H., Yahagi, N., Sakoda, H., Onishi, Y., Anai, M., Ogihara, T., Fujishiro, M., Viana, A. Y., Fukushima, Y., Abe, M., Shojima, N., Kikuchi, M., Yamada, N., Oka, Y., and Asano, T. (2003) Diabetes 52, 2905-2913
38. Taniguchi, C. M., Kondo, T., Sajan, M., Luo, J., Bronson, R., Asano, T., Farese, R., Cantley, L. C., and Kahn, C. R. (2006) Cell Metab. 3, 343-353
39. Sundqvist, A., Bengoechea-Alonso, M. T., Ye, X., Lukiyanchuk, V., Jin, J., Harper, J. W., and Ericsson, J. (2005) Cell Metab. 1, 379-391
40. Zhang, W., Patil, S., Chauhan, B., Guo, S., Powell, D. R., Le, J., Klotsas, A., Matika, R., Xiao, X., Franks, R., Heidenreich, K. A., Sajan, M. P., Farese, R. V., Stolz, D. B., Tso, P., Koo, S. H., Montminy, M., and Unterman, T. G. (2006) J. Biol. Chem. 281, 10105-10117
41. Kubota, N., Kubota, T., Itoh, S., Kumagai, H., Kozono, H., Takamoto, I., Mineyama, T., Ogata, H., Tokuyama, K., Ohsugi, M., Sasako, T., Moroi, M., Sugi, K., Kakuta, S., Iwakura, Y., Noda, T., Ohnishi, S., Nagai, R., Tobe, K., Terauchi, Y., Ueki, K., and Kadowaki, T. (2008) Cell Metab. 8, 49-64
42. Matsumoto, M., Ogawa, W., Teshigawara, K., Inoue, H., Miyake, K., Sakaue, H., and Kasuga, M. (2002) Diabetes 51, 1672-1680
43. Botolin, D., Wang, Y., Christian, B., and Jump, D. B. (2006) J. Lipid Res. 47, 181-192
44. Foretz, M., Pacot, C., Dugail, I., Lemarchand, P., Guichard, C., Le Liepvre, X., Berthelier-Lubrano, C., Spiegelman, B., Kim, J. B., Ferre, P., and Foufelle, F. (1999) Mol. Cell. Biol. 19, 3760-3768
45. Yamamoto, T., Shimano, H., Inoue, N., Nakagawa, Y., Matsuzaka, T., Takahashi, A., Yahagi, N., Sone, H., Suzuki, H., Toyoshima, H., and Yamada, N. (2007) J. Biol. Chem. 282, 11687-11695
46. Foretz, M., Ancellin, N., Andreelli, F., Saintillan, Y., Grondin, P., Kahn, A., Thorens, B., Vaulont, S., and Viollet, B. (2005) Diabetes 54, 1331-1339
47. Woods, A., Azzout-Marniche, D., Foretz, M., Stein, S. C., Lemarchand, P., Ferre, P., Foufelle, F., and Carling, D. (2000) Mol. Cell. Biol. 20, 6704-6711
48. Xiong, Y., Collins, Q. F., An, J., Lupo, E., Jr., Liu, H. Y., Liu, D., Robidoux, J., Liu, Z., and Cao, W. (2007) J. Biol. Chem. 282, 4975-4982
49. Lin, J., Yang, R., Tarr, P. T., Wu, P. H., Handschin, C., Li, S., Yang, W., Pei, L., Uldry, M., Tontonoz, P., Newgard, C. B., and Spiegelman, B. M. (2005) Cell 120, 261-273
50. Handschin, C., and Spiegelman, B. M. (2006) Endocr. Rev. 27, 728-735
51. Bavner, A., Sanyal, S., Gustafsson, J. A., and Treuter, E. (2005) Trends Endocrinol. Metab. 16, 478-488
52. Kerr, T. A., Saeki, S., Schneider, M., Schaefer, K., Berdy, S., Redder, T., Shan, B., Russell, D. W., and Schwarz, M. (2002) Dev. Cell 2, 713-720
53. Matsukuma, K. E., Wang, L., Bennett, M. K., and Osborne, T. F. (2007) J. Biol. Chem. 282, 20164-20171
54. Wang, L., Huang, J., Saha, P., Kulkarni, R. N., Hu, M., Kim, Y., Park, K., Chan, L., Rajan, A. S., Lee, I., and Moore, D. D. (2006) Mol. Endocrinol. 20, 2671-2681
55. Inoue, H., Ogawa, W., Ozaki, M., Haga, S., Matsumoto, M., Furukawa, K., Hashimoto, N., Kido, Y., Mori, T., Sakaue, H., Teshigawara, K., Jin, S., Iguchi, H., Hiramatsu, R., LeRoith, D., Takeda, K., Akira, S., and Kasuga, M. (2004) Nat. Med. 10, 168-174
56. Ueki, K., Kondo, T., Tseng, Y. H., and Kahn, C. R. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 10422-10427
57. Wen, Z., Zhong, Z., and Darnell, J. E., Jr. (1995) Cell 82, 241-250
58. Choi, C. S., Savage, D. B., Abu-Elheiga, L., Liu, Z. X., Kim, S., Kulkarni, A., Distefano, A., Hwang, Y. J., Reznick, R. M., Codella, R., Zhang, D., Cline, G. W., Wakil, S. J., and Shulman, G. I. (2007) Proc. Natl. Acad. Sci. U. S. A. 104, 16480-16485
59. Deng, X., Yellaturu, C., Cagen, L., Wilcox, H. G., Park, E. A., Raghow, R., and Elam, M. B. (2007) J. Biol. Chem. 282, 17517-17529
60. Hirota, K., Sakamaki, J. I., Ishida, J., Shimamoto, Y., Nishihara, S., Kodama, N., Ohta, K., Yamamoto, M., Tanimoto, K., and Fukamizu, A. (2008) J. Biol. Chem. 283, 32432-32441
61. Roth, U., Curth, K., Unterman, T. G., and Kietzmann, T. (2004) J. Biol. Chem. 279, 2623-2631
62. Lee, Y. K., Dell, H., Dowhan, D. H., Hadzopoulou-Cladaras, M., and Moore, D. D. (2000) Mol. Cell. Biol. 20, 187-195
63. Streeper, R. S., Chapman, S. C., Ayala, J. E., Svitek, C. A., Goldman, J. K., Cave, A., and O'Brien, R. M. (1998) Mol. Endocrinol. 12, 1778-1791
64. Salati, L. M., Szeszel-Fedorowicz, W., Tao, H., Gibson, M. A., Amir-Ahmady, B., Stabile, L. P., and Hodge, D. L. (2004) J. Nutr. 134, 2437S-2443S
65. Coskun, T., Bina, H. A., Schneider, M. A., Dunbar, J. D., Hu, C. C., Chen, Y., Moller, D. E., and Kharitonenkov, A. (2008) Endocrinology 149, 6018-6027
66. Xu, J., Lloyd, D. J., Hale, C., Stanislaus, S., Chen, M., Sivits, G., Vonderfecht, S. N., Hecht, R., Li, L., Lindberg, R. A., Chen, J. L., Jung, D. Y., Zhang, Z., Ko, H. J., Kim, J. K., and Veniant, M. M. (2009) Diabetes 58, 250-259