FGF21 acts centrally to induce sympathetic nerve activity, energy expenditure, and weight loss

Cell Metabolism

Volumn 20, Issue 4, 2014, Pages 670-677

  Owen, Bryn M ^a   Ding, Xunshan ^a,b,d   Morgan, Donald A ^c   Coate, Katie Colbert ^a,b   Bookout, Angie L ^a   Rahmouni, Kamal ^c   Kliewer, Steven A ^a,b   Mangelsdorf, David J ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d NGM Biopharmaceuticals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 TERT BUTYL 3 [6 (3,5 DIMETHOXYPHENYL) 2 (4 DIETHYLAMINOBUTYLAMINO)PYRIDO[2,3 D]PYRIMIDIN 7 YL]UREA; BETAKLOTHO RECEPTOR; CORTICOTROPIN RELEASING FACTOR; FIBROBLAST GROWTH FACTOR 21; FIBROBLAST GROWTH FACTOR RECEPTOR; UNCLASSIFIED DRUG; FIBROBLAST GROWTH FACTOR; KLB PROTEIN, MOUSE; MEMBRANE PROTEIN; MESSENGER RNA;

ADRENERGIC STIMULATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; DRUG MECHANISM; ENERGY EXPENDITURE; HYPOTHALAMUS; LIPID DIET; MALE; MOUSE; NERVE FUNCTION; NONHUMAN; OBESITY; SYMPATHETIC NERVE; SYMPATHETIC NERVE ACTIVITY; WEIGHT REDUCTION; ADRENERGIC SYSTEM; ANIMAL; C57BL MOUSE; DEFICIENCY; DRUG EFFECTS; ENERGY METABOLISM; GENETICS; KNOCKOUT MOUSE; METABOLISM; MOUSE MUTANT; THERMOGENESIS; TRANSGENIC MOUSE;

ADIPOSE TISSUE, BROWN; ANIMALS; CORTICOTROPIN-RELEASING HORMONE; ENERGY METABOLISM; FIBROBLAST GROWTH FACTORS; HYPOTHALAMUS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICE, OBESE; MICE, TRANSGENIC; RNA, MESSENGER; SYMPATHETIC NERVOUS SYSTEM; THERMOGENESIS; WEIGHT LOSS;

EID: 84908018672     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2014.07.012     Document Type: Article

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