-
1
-
-
84874084734
-
Role of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma
-
Hernandez-Gea V, Toffanin S, Friedman SL, et al. Role of the microenvironment in the pathogenesis and treatment of hepatocellular carcinoma. Gastroenterology 2013; 144: 512-27.
-
(2013)
Gastroenterology
, vol.144
, pp. 512-527
-
-
Hernandez-Gea, V.1
Toffanin, S.2
Friedman, S.L.3
-
4
-
-
56949101730
-
Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention
-
Ho HK, Pok S, Streit S, et al. Fibroblast growth factor receptor 4 regulates proliferation, anti-apoptosis and alpha-fetoprotein secretion during hepatocellular carcinoma progression and represents a potential target for therapeutic intervention. J Hepatol 2009; 50: 118-27.
-
(2009)
J Hepatol
, vol.50
, pp. 118-127
-
-
Ho, H.K.1
Pok, S.2
Streit, S.3
-
5
-
-
79952497178
-
Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by Oncogenomic screening
-
Sawey ET, Chanrion M, Cai C, et al. Identification of a therapeutic strategy targeting amplified FGF19 in liver cancer by Oncogenomic screening. Cancer Cell 2011; 19: 347-58.
-
(2011)
Cancer Cell
, vol.19
, pp. 347-358
-
-
Sawey, E.T.1
Chanrion, M.2
Cai, C.3
-
6
-
-
84856565638
-
Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinoma
-
Miura S, Mitsuhashi N, Shimizu H, et al. Fibroblast growth factor 19 expression correlates with tumor progression and poorer prognosis of hepatocellular carcinoma. BMC Cancer 2012; 12: 56.
-
(2012)
BMC Cancer
, vol.12
, pp. 56
-
-
Miura, S.1
Mitsuhashi, N.2
Shimizu, H.3
-
7
-
-
37849029159
-
Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models
-
Desnoyers LR, Pai R, Ferrando RE, et al. Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models. Oncogene 2008; 27: 85-97.
-
(2008)
Oncogene
, vol.27
, pp. 85-97
-
-
Desnoyers, L.R.1
Pai, R.2
Ferrando, R.E.3
-
8
-
-
84866171951
-
Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse models
-
French DM, Lin BC, Wang M, et al. Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse models. PLoS One 2012; 7: e36713.
-
(2012)
PLoS One
, vol.7
, pp. e36713
-
-
French, D.M.1
Lin, B.C.2
Wang, M.3
-
9
-
-
0036086285
-
A mouse model of hepatocellular carcinoma: Ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice
-
Nicholes K, Guillet S, Tomlinson E, et al. A mouse model of hepatocellular carcinoma: ectopic expression of fibroblast growth factor 19 in skeletal muscle of transgenic mice. Am J Pathol 2002; 160: 2295-307.
-
(2002)
Am J Pathol
, vol.160
, pp. 2295-2307
-
-
Nicholes, K.1
Guillet, S.2
Tomlinson, E.3
-
10
-
-
84876934226
-
Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in mice
-
Uriarte I, Fernández-Barrena MG, Monte MJ, et al. Identification of fibroblast growth factor 15 as a novel mediator of liver regeneration and its application in the prevention of post-resection liver failure in mice. Gut 2013; 62: 899-910.
-
(2013)
Gut
, vol.62
, pp. 899-910
-
-
Uriarte, I.1
Fernández-Barrena, M.G.2
Monte, M.J.3
-
11
-
-
84859812538
-
Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4
-
Dapito DH, Mencin A, Gwak G-Y, et al. Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4. Cancer Cell 2012; 21: 504-16.
-
(2012)
Cancer Cell
, vol.21
, pp. 504-516
-
-
Dapito, D.H.1
Mencin, A.2
Gwak, G.-Y.3
-
12
-
-
21444455580
-
Novel role for amphiregulin in protection from liver injury
-
Berasain C, García-Trevijano ER, Castillo J, et al. Novel role for amphiregulin in protection from liver injury. J Biol Chem 2005; 280: 19012-20.
-
(2005)
J Biol Chem
, vol.280
, pp. 19012-19020
-
-
Berasain, C.1
García-Trevijano, E.R.2
Castillo, J.3
-
13
-
-
84155178059
-
Nicotinamide inhibits the early stage of carcinogen-induced hepatocarcinogenesis in mice and suppresses human hepatocellular carcinoma cell growth
-
Park SY, Lee KB, Lee M-J, et al. Nicotinamide inhibits the early stage of carcinogen-induced hepatocarcinogenesis in mice and suppresses human hepatocellular carcinoma cell growth. J Cell Physiol 2012; 227: 899-908.
-
(2012)
J Cell Physiol
, vol.227
, pp. 899-908
-
-
Park, S.Y.1
Lee, K.B.2
Lee, M.-J.3
-
15
-
-
65449128051
-
Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential
-
Moles A, Tarrats N, Fernández-Checa JC, et al. Cathepsins B and D drive hepatic stellate cell proliferation and promote their fibrogenic potential. Hepatology 2009; 49: 1297-307.
-
(2009)
Hepatology
, vol.49
, pp. 1297-1307
-
-
Moles, A.1
Tarrats, N.2
Fernández-Checa, J.C.3
-
16
-
-
71549138697
-
The epidermal growth factor receptor ligand amphiregulin is a negative regulator of hepatic acute-phase gene expression
-
Pardo-Saganta A, Pardo-Saganta A, Latasa MU, et al. The epidermal growth factor receptor ligand amphiregulin is a negative regulator of hepatic acute-phase gene expression. J Hepatol 2009; 51: 1010-20.
-
(2009)
J Hepatol
, vol.51
, pp. 1010-1020
-
-
Pardo-Saganta, A.1
Pardo-Saganta, A.2
Latasa, M.U.3
-
17
-
-
82455210238
-
Connective tissue growth factor autocriny in human hepatocellular carcinoma: Oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activation
-
Urtasun R, Latasa MU, Demartis MI, et al. Connective tissue growth factor autocriny in human hepatocellular carcinoma: oncogenic role and regulation by epidermal growth factor receptor/yes-associated protein-mediated activation. Hepatology 2011; 54: 2149-58.
-
(2011)
Hepatology
, vol.54
, pp. 2149-2158
-
-
Urtasun, R.1
Latasa, M.U.2
Demartis, M.I.3
-
18
-
-
48949084865
-
Connective tissue growth factor: A fibrogenic master switch in fibrotic liver diseases
-
Gressner OA, Gressner AM,. Connective tissue growth factor: a fibrogenic master switch in fibrotic liver diseases. Liver Int 2008; 28: 1065-79.
-
(2008)
Liver Int
, vol.28
, pp. 1065-1079
-
-
Gressner, O.A.1
Gressner, A.M.2
-
19
-
-
84871432729
-
Regulation of amphiregulin gene expression by β-catenin signaling in human hepatocellular carcinoma cells: A novel crosstalk between FGF19 and the EGFR system
-
Latasa MU, Salis F, Urtasun R, et al. Regulation of amphiregulin gene expression by β-catenin signaling in human hepatocellular carcinoma cells: a novel crosstalk between FGF19 and the EGFR system. PLoS One 2012; 7: e52711.
-
(2012)
PLoS One
, vol.7
, pp. e52711
-
-
Latasa, M.U.1
Salis, F.2
Urtasun, R.3
-
20
-
-
65749086156
-
Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis
-
Huang X, Yang C, Jin C, et al. Resident hepatocyte fibroblast growth factor receptor 4 limits hepatocarcinogenesis. Mol Carcinog 2009; 48: 553-62.
-
(2009)
Mol Carcinog
, vol.48
, pp. 553-562
-
-
Huang, X.1
Yang, C.2
Jin, C.3
-
21
-
-
35448964238
-
Loss of hepatocyte growth factor/c-Met signaling pathway accelerates early stages of N-nitrosodiethylamine induced hepatocarcinogenesis
-
Takami T, Kaposi-Novak P, Uchida K, et al. Loss of hepatocyte growth factor/c-Met signaling pathway accelerates early stages of N-nitrosodiethylamine induced hepatocarcinogenesis. Cancer Res 2007; 67: 9844-51.
-
(2007)
Cancer Res
, vol.67
, pp. 9844-9851
-
-
Takami, T.1
Kaposi-Novak, P.2
Uchida, K.3
-
22
-
-
84870489524
-
Promotion of liver regeneration/repair by farnesoid X receptor in both liver and intestine in mice
-
Zhang L, Wang Y-D, Chen W-D, et al. Promotion of liver regeneration/repair by farnesoid X receptor in both liver and intestine in mice. Hepatology 2012; 56: 2336-43.
-
(2012)
Hepatology
, vol.56
, pp. 2336-2343
-
-
Zhang, L.1
Wang, Y.-D.2
Chen, W.-D.3
-
24
-
-
84893785854
-
Carbohydrate feeding dissociates the postprandial FGF19 response from circulating bile acid levels in humans
-
Morton GJ, Kaiyala KJ, Foster-Schubert KE, et al. Carbohydrate feeding dissociates the postprandial FGF19 response from circulating bile acid levels in humans. J Clin Endocrinol Metab 2014; 99: E241-5.
-
(2014)
J Clin Endocrinol Metab
, vol.99
, pp. E241-E245
-
-
Morton, G.J.1
Kaiyala, K.J.2
Foster-Schubert, K.E.3
-
25
-
-
84924315402
-
A genomic portrait of resectable hepatocellular carcinomas: Implications of RB1 and FGF19 aberrations for patient stratification
-
in press.
-
Ahn S-M, Jang SJ, Shim JH, et al. A genomic portrait of resectable hepatocellular carcinomas: Implications of RB1 and FGF19 aberrations for patient stratification. Hepatology, in press.
-
Hepatology
-
-
Ahn, S.-M.1
Jang, S.J.2
Shim, J.H.3
|