Nuclear receptors HNF4α and LRH-1 cooperate in regulating Cyp7a1 in vivo

Journal of Biological Chemistry

Volumn 287, Issue 49, 2012, Pages 41334-41341

  Kir, Serkan ^a   Zhang, Yuan ^a   Gerard, Robert D ^a,b   Kliewer, Steven A ^a,b   Mangelsdorf, David J ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; DUAL ROLE; FIBROBLAST GROWTH FACTOR; HYDROXYLASES; IN-VIVO; NUCLEAR RECEPTORS; TRANSCRIPTIONAL REPRESSION;

TRANSCRIPTION; TRANSCRIPTION FACTORS;

BODY FLUIDS;

BILE ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE; FIBROBLAST GROWTH FACTOR 19; HEPATOCYTE NUCLEAR FACTOR 4ALPHA; LIVER RECEPTOR HOMOLOG 1; PROTEIN TYROSINE PHOSPHATASE SHP;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BILE ACID SYNTHESIS; BINDING AFFINITY; BINDING SITE; CONTROLLED STUDY; DEACYLATION; DEMETHYLATION; DOWN REGULATION; ENZYME REPRESSION; IN VIVO STUDY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION; UPREGULATION;

ANIMALS; BILE ACIDS AND SALTS; BINDING SITES; CHOLESTEROL 7-ALPHA-HYDROXYLASE; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION; HEK293 CELLS; HEPATOCYTE NUCLEAR FACTOR 4; HISTONES; HUMANS; LIVER; MICE; PROMOTER REGIONS, GENETIC; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 6; RECEPTORS, CYTOPLASMIC AND NUCLEAR; TRANSCRIPTION, GENETIC;

EID: 84870334072     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.421834     Document Type: Article

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