Hepatocyte FRS2α is essential for the endocrine fibroblast growth factor to limit the amplitude of bile acid production induced by prandial activity

Current Molecular Medicine

Volumn 14, Issue 6, 2014, Pages 703-711

  Wang, C ^a,b   Yang, C ^b,e   Chang, J Y F ^b,f   You, P ^c   Li, Y ^d   Jin, C ^b,g   Luo, Y ^b   Li, X ^a   McKeehan, W L ^b   Wang, F ^b  

^a WENZHOU MEDICAL UNIVERSITY   (China)

^b TEXAS A AND M HEALTH SCIENCE CENTER   (United States)

^c ZHONGSHAN HOSPITAL OF XIAMEN UNIVERSITY   (China)

^d HARBIN MEDICAL UNIVERSITY   (China)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^f UNIVERSITY OF WASHINGTON   (United States)

^g GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Bile acid; CYP7A1; FGF15 FGF19; Fgfr4; FRS2

Indexed keywords

CHOLESTEROL 7ALPHA MONOOXYGENASE; FIBROBLAST GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 4; MESSENGER RNA; BILE ACID; CYP7A1 PROTEIN, MOUSE; FIBROBLAST GROWTH FACTOR RECEPTOR 4; FRS2ALPHA PROTEIN, MOUSE; MEMBRANE PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE ACID SYNTHESIS; BODY WEIGHT; CONTROLLED STUDY; DOWNSTREAM PROCESSING; FLUORESCENCE IN SITU HYBRIDIZATION; GENE EXPRESSION; GENE OVEREXPRESSION; HISTOLOGY; HOMEOSTASIS; LIVER CELL; LIVER WEIGHT; MALE; MAP KINASE ASSAY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION; WESTERN BLOTTING; ALLELE; ANIMAL; BIOSYNTHESIS; CYTOLOGY; DEFICIENCY; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; LIVER; METABOLISM; TRANSGENIC MOUSE;

ALLELES; ANIMALS; BILE ACIDS AND SALTS; BODY WEIGHT; CHOLESTEROL 7-ALPHA-HYDROXYLASE; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION; GENOTYPE; HEPATOCYTES; LIVER; MALE; MEMBRANE PROTEINS; MICE; MICE, TRANSGENIC; RECEPTOR, FIBROBLAST GROWTH FACTOR, TYPE 4; SIGNAL TRANSDUCTION;

EID: 84906239059     PISSN: 15665240     EISSN: 18755666     Source Type: Journal    
DOI: 10.2174/1566524014666140724095112     Document Type: Article

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