-
1
-
-
78049499084
-
Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity
-
Abbas, H. A, MacCio, D. R., Coskun, S., Jackson, J. G., Hazen, A. L., Sills, T. M., You, M. J., Hirschi, K. K. and Lozano, G. (2010). Mdm2 is required for survival of hematopoietic stem cells/progenitors via dampening of ROS-induced p53 activity. Cell Stem Cell 7, 606-617.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 606-617
-
-
Abbas, H.A.1
Maccio, D.R.2
Coskun, S.3
Jackson, J.G.4
Hazen, A.L.5
Sills, T.M.6
You, M.J.7
Hirschi, K.K.8
Lozano, G.9
-
2
-
-
82755166890
-
Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses
-
Anastasiou, D., Poulogiannis, G., Asara, J. M., Boxer, M. B., Jiang, J.-k., Shen, M., Bellinger, G., Sasaki, A. T., Locasale, J. W., Auld, D. S. et al. (2011). Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses. Science 334, 1278-1283.
-
(2011)
Science
, vol.334
, pp. 1278-1283
-
-
Anastasiou, D.1
Poulogiannis, G.2
Asara, J.M.3
Boxer, M.B.4
Jiang, J.-K.5
Shen, M.6
Bellinger, G.7
Sasaki, A.T.8
Locasale, J.W.9
Auld, D.S.10
-
3
-
-
0035988381
-
Redox factor-1: An extra-nuclear role in the regulation of endothelial oxidative stress and apoptosis
-
Angkeow, P., Deshpande, S. S., Qi, B., Liu, Y.-X., Park, Y. C., Jeon, B. H., Ozaki, M. and Irani, K. (2002). Redox factor-1: an extra-nuclear role in the regulation of endothelial oxidative stress and apoptosis. Cell Death Differ. 9, 717-725.
-
(2002)
Cell Death Differ
, vol.9
, pp. 717-725
-
-
Angkeow, P.1
Deshpande, S.S.2
Qi, B.3
Liu, Y.-X.4
Park, Y.C.5
Jeon, B.H.6
Ozaki, M.7
Irani, K.8
-
4
-
-
77951021307
-
Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells
-
Armstrong, L., Tilgner, K., Saretzki, G., Atkinson, S. P., Stojkovic, M., Moreno, R., Przyborski, S. and Lako, M. (2010). Human induced pluripotent stem cell lines show stress defense mechanisms and mitochondrial regulation similar to those of human embryonic stem cells. Stem Cells 28, 661-673.
-
(2010)
Stem Cells
, vol.28
, pp. 661-673
-
-
Armstrong, L.1
Tilgner, K.2
Saretzki, G.3
Atkinson, S.P.4
Stojkovic, M.5
Moreno, R.6
Przyborski, S.7
Lako, M.8
-
5
-
-
84866447416
-
The evolving concept of cancer and metastasis stem cells
-
Baccelli, I. and Trumpp, A. (2012). The evolving concept of cancer and metastasis stem cells. J. Cell Biol. 198, 281-293.
-
(2012)
J. Cell Biol
, vol.198
, pp. 281-293
-
-
Baccelli, I.1
Trumpp, A.2
-
6
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman, K. B. and Ames, B. N. (1998). The free radical theory of aging matures. Physiol. Rev. 78, 547-581.
-
(1998)
Physiol. Rev
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
7
-
-
77956293210
-
REX-1 expression and p38 MAPK activation status can determine proliferation/differentiation fates in human mesenchymal stem cells
-
Bhandari, D. R., Seo, K.-W., Roh, K.-H., Jung, J.-W., Kang, S.-K. and Kang, K.-S. (2010). REX-1 expression and p38 MAPK activation status can determine proliferation/differentiation fates in human mesenchymal stem cells. PLoS ONE 5, e10493.
-
(2010)
PLoS ONE
, vol.5
, pp. 10493
-
-
Bhandari, D.R.1
Seo, K.-W.2
Roh, K.-H.3
Jung, J.-W.4
Kang, S.-K.5
Kang, K.-S.6
-
8
-
-
34247187576
-
Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site
-
Bonello, S, Zaöhringer, C, BelAiba, R. S, Djordjevic, T, Hess, J, Michiels, C, Kietzmann, T. and Goörlach, A. (2007). Reactive oxygen species activate the HIF-1alpha promoter via a functional NFkappaB site. Arterioscler. Thromb. Vasc. Biol. 27, 755-761.
-
(2007)
Arterioscler. Thromb. Vasc. Biol
, vol.27
, pp. 755-761
-
-
Bonello, S.1
Zaáhringer, C.2
Belaiba, R.S.3
Djordjevic, T.4
Hess, J.5
Michiels, C.6
Kietzmann, T.7
Goörlach, A.8
-
9
-
-
84874238886
-
SIRT3 reverses aging-associated degeneration
-
Brown, K., Xie, S., Qiu, X., Mohrin, M., Shin, J., Liu, Y., Zhang, D., Scadden, D. T. and Chen, D. (2013). SIRT3 reverses aging-associated degeneration. Cell Rep. 3, 319-327.
-
(2013)
Cell Rep
, vol.3
, pp. 319-327
-
-
Brown, K.1
Xie, S.2
Qiu, X.3
Mohrin, M.4
Shin, J.5
Liu, Y.6
Zhang, D.7
Scadden, D.T.8
Chen, D.9
-
10
-
-
24144444133
-
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation
-
Brunelle, J. K., Bell, E. L., Quesada, N. M., Vercauteren, K., Tiranti, V., Zeviani, M., Scarpulla, R. C. and Chandel, N. S. (2005). Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation. Cell Metabol. 1, 409-414.
-
(2005)
Cell Metabol
, vol.1
, pp. 409-414
-
-
Brunelle, J.K.1
Bell, E.L.2
Quesada, N.M.3
Vercauteren, K.4
Tiranti, V.5
Zeviani, M.6
Scarpulla, R.C.7
Chandel, N.S.8
-
11
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet, A., Sweeney, L. B., Sturgill, J. F., Chua, K. F., Greer, P. L., Lin, Y., Tran, H., Ross, S. E., Mostoslavsky, R., Cohen, H. Y. et al. (2004). Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303, 2011-2015.
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mostoslavsky, R.9
Cohen, H.Y.10
-
12
-
-
84555207349
-
Dnmt3a is essential for hematopoietic stem cell differentiation
-
Challen, G. A., Sun, D., Jeong, M., Luo, M., Jelinek, J., Berg, J. S., Bock, C., Vasanthakumar, A., Gu, H., Xi, Y. et al. (2012). Dnmt3a is essential for hematopoietic stem cell differentiation. Nat. Genet. 44, 23-31.
-
(2012)
Nat. Genet
, vol.44
, pp. 23-31
-
-
Challen, G.A.1
Sun, D.2
Jeong, M.3
Luo, M.4
Jelinek, J.5
Berg, J.S.6
Bock, C.7
Vasanthakumar, A.8
Gu, H.9
Xi, Y.10
-
13
-
-
0032578458
-
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
-
Chandel, N. S., Maltepe, E., Goldwasser, E., Mathieu, C. E., Simon, M. C. and Schumacker, P. T. (1998). Mitochondrial reactive oxygen species trigger hypoxia-induced transcription. Proc. Natl. Acad. Sci. USA 95, 11715-11720.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 11715-11720
-
-
Chandel, N.S.1
Maltepe, E.2
Goldwasser, E.3
Mathieu, C.E.4
Simon, M.C.5
Schumacker, P.T.6
-
14
-
-
53349091768
-
TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
-
Chen, C., Liu, Y., Liu, R., Ikenoue, T., Guan, K.-L., Liu, Y. and Zheng, P. (2008). TSC-mTOR maintains quiescence and function of hematopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J. Exp. Med. 205, 2397-2408.
-
(2008)
J. Exp. Med
, vol.205
, pp. 2397-2408
-
-
Chen, C.1
Liu, Y.2
Liu, R.3
Ikenoue, T.4
Guan, K.-L.5
Liu, Y.6
Zheng, P.7
-
15
-
-
77957551487
-
Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress
-
Chuikov, S., Levi, B. P., Smith, M. L. and Morrison, S. J. (2010). Prdm16 promotes stem cell maintenance in multiple tissues, partly by regulating oxidative stress. Nat. Cell Biol. 12, 999-1006.
-
(2010)
Nat. Cell Biol
, vol.12
, pp. 999-1006
-
-
Chuikov, S.1
Levi, B.P.2
Smith, M.L.3
Morrison, S.J.4
-
16
-
-
33846501510
-
Mitochondrial oxidative metabolism is required for the cardiac differentiation of stem cells
-
Chung, S., Dzeja, P. P., Faustino, R. S., Perez-Terzic, C., Behfar, A. and Terzic, A. (2007). Mitochondrial oxidative metabolism is required for the cardiac differentiation of stem cells. Nat. Clin. Pract. Cardiovasc. Med. 4 Suppl. 1, S60-S67.
-
(2007)
Nat. Clin. Pract. Cardiovasc. Med
, vol.1
, Issue.4
, pp. S60-S67
-
-
Chung, S.1
Dzeja, P.P.2
Faustino, R.S.3
Perez-Terzic, C.4
Behfar, A.5
Terzic, A.6
-
17
-
-
3042750643
-
Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity
-
Daitoku, H., Hatta, M., Matsuzaki, H., Aratani, S., Ohshima, T., Miyagishi, M., Nakajima, T. and Fukamizu, A. (2004). Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity. Proc. Natl. Acad. Sci. U. S. A. 101, 10042-10047.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A
, vol.101
, pp. 10042-10047
-
-
Daitoku, H.1
Hatta, M.2
Matsuzaki, H.3
Aratani, S.4
Ohshima, T.5
Miyagishi, M.6
Nakajima, T.7
Fukamizu, A.8
-
18
-
-
69249229450
-
Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity
-
Dansen, T. B., Smits, L. M. M., van Triest, M. H., de Keizer, P. L. J., van Leenen, D., Koerkamp, M. G., Szypowska, A., Meppelink, A., Brenkman, A. B., Yodoi, J. et al. (2009). Redox-sensitive cysteines bridge p300/CBP-mediated acetylation and FoxO4 activity. Nat. Chem. Biol. 5, 664-672.
-
(2009)
Nat. Chem. Biol
, vol.5
, pp. 664-672
-
-
Dansen, T.B.1
Smits, L.M.M.2
Van Triest, M.H.3
De Keizer, P.L.J.4
Van Leenen, D.5
Koerkamp, M.G.6
Szypowska, A.7
Meppelink, A.8
Brenkman, A.B.9
Yodoi, J.10
-
19
-
-
84881119066
-
Role of PFKFB3-driven glycolysis in vessel sprouting
-
De Bock, K., Georgiadou, M., Schoors, S., Kuchnio, A, Wong, B.W, Cantelmo, A. R, Quaegebeur, A, Ghesquière, B, Cauwenberghs, S, Eelen, G. et al. (2013). Role of PFKFB3-driven glycolysis in vessel sprouting. Cell 154, 651-663.
-
(2013)
Cell
, vol.154
, pp. 651-663
-
-
De Bock, K.1
Georgiadou, M.2
Schoors, S.3
Kuchnio, A.4
Wong, B.W.5
Cantelmo, A.R.6
Quaegebeur, A.7
Ghesquieère, B.8
Cauwenberghs, S.9
Eelen, G.10
-
20
-
-
64749093574
-
Association of reactive oxygen species levels and radioresistance in cancer stem cells
-
Diehn, M., Cho, R.W., Lobo, N. A., Kalisky, T., Dorie, M. J., Kulp, A. N., Qian, D., Lam, J. S., Ailles, L. E., Wong, M., et al. (2009). Association of reactive oxygen species levels and radioresistance in cancer stem cells. Nature 458, 780-783.
-
(2009)
Nature
, vol.458
, pp. 780-783
-
-
Diehn, M.1
Cho, R.W.2
Lobo, N.A.3
Kalisky, T.4
Dorie, M.J.5
Kulp, A.N.6
Qian, D.7
Lam, J.S.8
Ailles, L.E.9
Wong, M.10
-
21
-
-
51849108636
-
Involvement of p38MAPK and reactive oxygen species in icariin-induced cardiomyocyte differentiation of murine embryonic stem cells in vitro
-
Ding, L., Liang, X.-G., Hu, Y., Zhu, D.-Y. and Lou, Y.-J. (2008). Involvement of p38MAPK and reactive oxygen species in icariin-induced cardiomyocyte differentiation of murine embryonic stem cells in vitro. Stem Cells Dev. 17, 751-760.
-
(2008)
Stem Cells Dev
, vol.17
, pp. 751-760
-
-
Ding, L.1
Liang, X.-G.2
Hu, Y.3
Zhu, D.-Y.4
Lou, Y.-J.5
-
22
-
-
0036977353
-
Aging-related changes in the thiol/disulfide redox state: Implications for the use of thiol antioxidants
-
Droöge, W. (2002). Aging-related changes in the thiol/disulfide redox state: implications for the use of thiol antioxidants. Exp. Gerontol. 37, 1333-1345.
-
(2002)
Exp. Gerontol
, vol.37
, pp. 1333-1345
-
-
Droöge, W.1
-
23
-
-
84891874604
-
Cited2 is required for the maintenance of glycolytic metabolism in adult hematopoietic stem cells
-
Du, J., Li, Q., Tang, F., Puchowitz, M. A., Fujioka, H., Dunwoodie, S. L., Danielpour, D. and Yang, Y.-C. (2014). Cited2 is required for the maintenance of glycolytic metabolism in adult hematopoietic stem cells. Stem Cells Dev. 23, 83-94.
-
(2014)
Stem Cells Dev
, vol.23
, pp. 83-94
-
-
Du, J.1
Li, Q.2
Tang, F.3
Puchowitz, M.A.4
Fujioka, H.5
Dunwoodie, S.L.6
Danielpour, D.7
Yang, Y.-C.8
-
24
-
-
17944375360
-
C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
-
Epstein, A. C. R., Gleadle, J. M., McNeill, L. A., Hewitson, K. S., O’Rourke, J., Mole, D. R., Mukherji, M., Metzen, E, Wilson, M. I, Dhanda, A. et al. (2001). C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation. Cell 107, 43-54.
-
(2001)
Cell
, vol.107
, pp. 43-54
-
-
Epstein, A.C.R.1
Gleadle, J.M.2
McNeill, L.A.3
Hewitson, K.S.4
O’rourke, J.5
Mole, D.R.6
Mukherji, M.7
Metzen, E.8
Wilson, M.I.9
Dhanda, A.10
-
25
-
-
16344380951
-
Low O2 tensions and the prevention of differentiation of hES cells
-
Ezashi, T., Das, P. and Roberts, R. M. (2005). Low O2 tensions and the prevention of differentiation of hES cells. Proc. Natl. Acad. Sci. USA 102, 4783-4788.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 4783-4788
-
-
Ezashi, T.1
Das, P.2
Roberts, R.M.3
-
26
-
-
0037376674
-
Oxidant signals and oxidative stress
-
Finkel, T. (2003). Oxidant signals and oxidative stress. Curr. Opin. Cell Biol. 15, 247-254.
-
(2003)
Curr. Opin. Cell Biol
, vol.15
, pp. 247-254
-
-
Finkel, T.1
-
27
-
-
79960286223
-
Signal transduction by reactive oxygen species
-
Finkel, T. (2011). Signal transduction by reactive oxygen species. J. Cell Biol. 194, 7-15.
-
(2011)
J. Cell Biol
, vol.194
, pp. 7-15
-
-
Finkel, T.1
-
28
-
-
79960945131
-
Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming
-
Folmes, C. D. L., Nelson, T. J., Martinez-Fernandez, A., Arrell, D. K., Lindor, J. Z., Dzeja, P. P., Ikeda, Y., Perez-Terzic, C. and Terzic, A. (2011). Somatic oxidative bioenergetics transitions into pluripotency-dependent glycolysis to facilitate nuclear reprogramming. Cell Metabol. 14, 264-271.
-
(2011)
Cell Metabol
, vol.14
, pp. 264-271
-
-
Folmes, C.D.L.1
Nelson, T.J.2
Martinez-Fernandez, A.3
Arrell, D.K.4
Lindor, J.Z.5
Dzeja, P.P.6
Ikeda, Y.7
Perez-Terzic, C.8
Terzic, A.9
-
29
-
-
84868347607
-
Metabolic plasticity in stem cell homeostasis and differentiation
-
Folmes, C. D. L., Dzeja, P. P., Nelson, T. J. and Terzic, A. (2012). Metabolic plasticity in stem cell homeostasis and differentiation. Cell Stem Cell 11, 596-606.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 596-606
-
-
Folmes, C.D.L.1
Dzeja, P.P.2
Nelson, T.J.3
Terzic, A.4
-
30
-
-
33645766052
-
Physiologic oxygen enhances human embryonic stem cell clonal recovery and reduces chromosomal abnormalities
-
Forsyth, N. R., Musio, A., Vezzoni, P., Simpson, A. H. R. W., Noble, B. S. and McWhir, J. (2006). Physiologic oxygen enhances human embryonic stem cell clonal recovery and reduces chromosomal abnormalities. Cloning Stem Cells 8, 16-23.
-
(2006)
Cloning Stem Cells
, vol.8
, pp. 16-23
-
-
Forsyth, N.R.1
Musio, A.2
Vezzoni, P.3
Simpson, A.H.R.W.4
Noble, B.S.5
McWhir, J.6
-
31
-
-
60149104597
-
Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells
-
Foudi, A., Hochedlinger, K., Van Buren, D., Schindler, J. W., Jaenisch, R., Carey, V. and Hock, H. (2009). Analysis of histone 2B-GFP retention reveals slowly cycling hematopoietic stem cells. Nat. Biotechnol. 27, 84-90.
-
(2009)
Nat. Biotechnol
, vol.27
, pp. 84-90
-
-
Foudi, A.1
Hochedlinger, K.2
Van Buren, D.3
Schindler, J.W.4
Jaenisch, R.5
Carey, V.6
Hock, H.7
-
32
-
-
4944225788
-
SOD2-deficiency anemia: Protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness
-
Friedman, J. S., Lopez, M. F., Fleming, M. D., Rivera, A., Martin, F. M., Welsh, M. L., Boyd, A., Doctrow, S. R. and Burakoff, S. J. (2004). SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness. Blood 104, 2565-2573.
-
(2004)
Blood
, vol.104
, pp. 2565-2573
-
-
Friedman, J.S.1
Lopez, M.F.2
Fleming, M.D.3
Rivera, A.4
Martin, F.M.5
Welsh, M.L.6
Boyd, A.7
Doctrow, S.R.8
Burakoff, S.J.9
-
33
-
-
34547509586
-
Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production
-
Funes, J. M., Quintero, M., Henderson, S., Martinez, D., Qureshi, U, Westwood, C, Clements, M. O, Bourboulia, D, Pedley, R. B, Moncada, S. et al. (2007). Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production. Proc. Natl. Acad. Sci. USA 104, 6223-6228.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 6223-6228
-
-
Funes, J.M.1
Quintero, M.2
Henderson, S.3
Martinez, D.4
Qureshi, U.5
Westwood, C.6
Clements, M.O.7
Bourboulia, D.8
Pedley, R.B.9
Moncada, S.10
-
34
-
-
78649874959
-
Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells
-
Gan, B., Hu, J., Jiang, S., Liu, Y., Sahin, E., Zhuang, L., Fletcher-Sananikone, E., Colla, S., Wang, Y. A., Chin, L. et al. (2010). Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells. Nature 468, 701-704.
-
(2010)
Nature
, vol.468
, pp. 701-704
-
-
Gan, B.1
Hu, J.2
Jiang, S.3
Liu, Y.4
Sahin, E.5
Zhuang, L.6
Fletcher-Sananikone, E.7
Colla, S.8
Wang, Y.A.9
Chin, L.10
-
35
-
-
84893442805
-
Declining NAD(+) induces a pseudohypoxic state disrupting nuclearmitochondrial communication during aging
-
Gomes, A. P., Price, N. L., Ling, A. J. Y., Moslehi, J. J., Montgomery, M. K., Rajman, L., White, J. P., Teodoro, J. S., Wrann, C. D., Hubbard, B. P. et al. (2013). Declining NAD(+) induces a pseudohypoxic state disrupting nuclearmitochondrial communication during aging. Cell 155, 1624-1638.
-
(2013)
Cell
, vol.155
, pp. 1624-1638
-
-
Gomes, A.P.1
Price, N.L.2
Ling, A.J.Y.3
Moslehi, J.J.4
Montgomery, M.K.5
Rajman, L.6
White, J.P.7
Teodoro, J.S.8
Wrann, C.D.9
Hubbard, B.P.10
-
36
-
-
2942566694
-
Redox regulation of the embryonic stem cell transcription factor oct-4 by thioredoxin
-
Guo, Y., Einhorn, L., Kelley, M., Hirota, K., Yodoi, J., Reinbold, R., Scholer, H., Ramsey, H. and Hromas, R. (2004). Redox regulation of the embryonic stem cell transcription factor oct-4 by thioredoxin. Stem Cells 22, 259-264.
-
(2004)
Stem Cells
, vol.22
, pp. 259-264
-
-
Guo, Y.1
Einhorn, L.2
Kelley, M.3
Hirota, K.4
Yodoi, J.5
Reinbold, R.6
Scholer, H.7
Ramsey, H.8
Hromas, R.9
-
37
-
-
77956427364
-
Effects of oxidative stress on mouse embryonic stem cell proliferation, apoptosis, senescence, and self-renewal
-
Guo, Y.-L., Chakraborty, S., Rajan, S. S, Wang, R. and Huang, F. (2010a). Effects of oxidative stress on mouse embryonic stem cell proliferation, apoptosis, senescence, and self-renewal. Stem Cells Dev. 19, 1321-1331.
-
(2010)
Stem Cells Dev
, vol.19
, pp. 1321-1331
-
-
Guo, Y.-L.1
Chakraborty, S.2
Rajan, S.S.3
Wang, R.4
Huang, F.5
-
38
-
-
77958191599
-
ATM activation by oxidative stress
-
Guo, Z., Kozlov, S., Lavin, M. F., Person, M. D. and Paull, T. T. (2010b). ATM activation by oxidative stress. Science 330, 517-521.
-
(2010)
Science
, vol.330
, pp. 517-521
-
-
Guo, Z.1
Kozlov, S.2
Lavin, M.F.3
Person, M.D.4
Paull, T.T.5
-
39
-
-
78649851511
-
The Lkb1 metabolic sensor maintains haematopoietic stem cell survival
-
Gurumurthy, S., Xie, S. Z., Alagesan, B., Kim, J., Yusuf, R. Z., Saez, B., Tzatsos, A., Ozsolak, F., Milos, P., Ferrari, F. et al. (2010). The Lkb1 metabolic sensor maintains haematopoietic stem cell survival. Nature 468, 659-663.
-
(2010)
Nature
, vol.468
, pp. 659-663
-
-
Gurumurthy, S.1
Xie, S.Z.2
Alagesan, B.3
Kim, J.4
Yusuf, R.Z.5
Saez, B.6
Tzatsos, A.7
Ozsolak, F.8
Milos, P.9
Ferrari, F.10
-
40
-
-
84886812954
-
The nexus of chromatin regulation and intermediary metabolism
-
Gut, P. and Verdin, E. (2013). The nexus of chromatin regulation and intermediary metabolism. Nature 502, 489-498.
-
(2013)
Nature
, vol.502
, pp. 489-498
-
-
Gut, P.1
Verdin, E.2
-
41
-
-
78649866553
-
Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1
-
Guzman, J. N., Sanchez-Padilla, J., Wokosin, D., Kondapalli, J., Ilijic, E., Schumacker, P. T. and Surmeier, D. J. (2010). Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1. N ature 468, 696-700.
-
(2010)
N ature
, vol.468
, pp. 696-700
-
-
Guzman, J.N.1
Sanchez-Padilla, J.2
Wokosin, D.3
Kondapalli, J.4
Ilijic, E.5
Schumacker, P.T.6
Surmeier, D.J.7
-
42
-
-
77949887506
-
Mammalian sirtuins: Biological insights and disease relevance
-
Haigis, M. C. and Sinclair, D. A. (2010). Mammalian sirtuins: biological insights and disease relevance. Annu. Rev. Pathol. 5, 253-295.
-
(2010)
Annu. Rev. Pathol
, vol.5
, pp. 253-295
-
-
Haigis, M.C.1
Sinclair, D.A.2
-
43
-
-
39749087530
-
SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization
-
Han, M.-K., Song, E.-K., Guo, Y., Ou, X., Mantel, C. and Broxmeyer, H. E. (2008). SIRT1 regulates apoptosis and Nanog expression in mouse embryonic stem cells by controlling p53 subcellular localization. Cell Stem Cell 2, 241-251.
-
(2008)
Cell Stem Cell
, vol.2
, pp. 241-251
-
-
Han, M.-K.1
Song, E.-K.2
Guo, Y.3
Ou, X.4
Mantel, C.5
Broxmeyer, H.E.6
-
44
-
-
0015383617
-
Free radical theory of aging: Dietary implications
-
Harman, D. (1972). Free radical theory of aging: dietary implications. Am. J. Clin. Nutr. 25, 839-843.
-
(1972)
Am. J. Clin. Nutr
, vol.25
, pp. 839-843
-
-
Harman, D.1
-
45
-
-
84878414798
-
Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo
-
Harris, J. M., Esain, V., Frechette, G. M., Harris, L. J., Cox, A. G., Cortes, M., Garnaas, M. K., Carroll, K. J., Cutting, C. C., Khan, T. et al. (2013). Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo. Blood 121, 2483-2493.
-
(2013)
Blood
, vol.121
, pp. 2483-2493
-
-
Harris, J.M.1
Esain, V.2
Frechette, G.M.3
Harris, L.J.4
Cox, A.G.5
Cortes, M.6
Garnaas, M.K.7
Carroll, K.J.8
Cutting, C.C.9
Khan, T.10
-
46
-
-
84863811010
-
A role for GPx3 in activity of normal and leukemia stem cells
-
Herault, O., Hope, K. J., Deneault, E., Mayotte, N., Chagraoui, J, Wilhelm, B. T, Cellot, S., Sauvageau, M, Andrade-Navarro M. A, Hebert, J. et al. (2012). A role for GPx3 in activity of normal and leukemia stem cells. J. Exp. Med. 209, 895-901.
-
(2012)
J. Exp. Med
, vol.209
, pp. 895-901
-
-
Herault, O.1
Hope, K.J.2
Deneault, E.3
Mayotte, N.4
Chagraoui, J.5
Wilhelm, B.T.6
Cellot, S.7
Sauvageau, M.8
Andrade-Navarro, M.A.9
HeBert, J.10
-
47
-
-
77953536606
-
Reactive oxygen species: A radical role in development?
-
Hernandez-Garcıa, D, Wood, C. D, Castro-Obregon, S and Covarrubias, L. (2010). Reactive oxygen species: a radical role in development? Free Radic. Biol. Med. 49, 130-143.
-
(2010)
Free Radic. Biol. Med
, vol.49
, pp. 130-143
-
-
Hernandez-Garcıa, D.1
Wood, C.D.2
Castro-Obregon, S.3
Covarrubias, L.4
-
48
-
-
6944226407
-
Birth weight and risk for childhood leukemia in Denmark, Sweden, Norway, and Iceland
-
Hjalgrim, L. L., Rostgaard, K., Hjalgrim, H., Westergaard, T., Thomassen, H., Forestier, E., Gustafsson, G., Kristinsson, J., Melbye, M. and Schmiegelow, K. (2004). Birth weight and risk for childhood leukemia in Denmark, Sweden, Norway, and Iceland. J. Natl. Cancer Inst. 96, 1549-1556.
-
(2004)
J. Natl. Cancer Inst
, vol.96
, pp. 1549-1556
-
-
Hjalgrim, L.L.1
Rostgaard, K.2
Hjalgrim, H.3
Westergaard, T.4
Thomassen, H.5
Forestier, E.6
Gustafsson, G.7
Kristinsson, J.8
Melbye, M.9
Schmiegelow, K.10
-
49
-
-
79551610653
-
Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila
-
Hochmuth, C. E., Biteau, B., Bohmann, D. and Jasper, H. (2011). Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila. Cell Stem Cell 8, 188-199.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 188-199
-
-
Hochmuth, C.E.1
Biteau, B.2
Bohmann, D.3
Jasper, H.4
-
50
-
-
84901316606
-
Cellular mechanisms and physiological consequences of redox-dependent signalling
-
Holmstroöm, K. M andFinkel, T. (2014). Cellular mechanisms and physiological consequences of redox-dependent signalling. Nat. Rev. Mol. Cell Biol. 15, 411-421.
-
(2014)
Nat. Rev. Mol. Cell Biol
, vol.15
, pp. 411-421
-
-
Holmstroöm, K.M.1
Finkel, T.2
-
51
-
-
80755129126
-
The permeability transition pore controls cardiac mitochondrial maturation and myocyte differentiation
-
Hom, J. R., Quintanilla, R. A., Hoffman, D. L., de Mesy Bentley, K. L., Molkentin, J. D., Sheu, S.-S. and Porter, G. A. (2011). The permeability transition pore controls cardiac mitochondrial maturation and myocyte differentiation. Dev. Cell 21, 469-478.
-
(2011)
Dev. Cell
, vol.21
, pp. 469-478
-
-
Hom, J.R.1
Quintanilla, R.A.2
Hoffman, D.L.3
De Mesy Bentley, K.L.4
Molkentin, J.D.5
Sheu, S.-S.6
Porter, G.A.7
-
52
-
-
0030980641
-
Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts
-
Irani, K., Xia, Y., Zweier, J. L., Sollott, S. J., Der, C. J., Fearon, E. R., Sundaresan, M., Finkel, T. and Goldschmidt-Clermont, P. J. (1997). Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science 275, 1649-1652.
-
(1997)
Science
, vol.275
, pp. 1649-1652
-
-
Irani, K.1
Xia, Y.2
Zweier, J.L.3
Sollott, S.J.4
Der, C.J.5
Fearon, E.R.6
Sundaresan, M.7
Finkel, T.8
Goldschmidt-Clermont, P.J.9
-
53
-
-
7244250309
-
Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells
-
Ito, K., Hirao, A., Arai, F., Matsuoka, S., Takubo, K., Hamaguchi, I., Nomiyama, K., Hosokawa, K., Sakurada, K., Nakagata, N. et al. (2004). Regulation of oxidative stress by ATM is required for self-renewal of haematopoietic stem cells. Nature 431, 997-1002.
-
(2004)
Nature
, vol.431
, pp. 997-1002
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Matsuoka, S.4
Takubo, K.5
Hamaguchi, I.6
Nomiyama, K.7
Hosokawa, K.8
Sakurada, K.9
Nakagata, N.10
-
54
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito, K., Hirao, A., Arai, F., Takubo, K., Matsuoka, S., Miyamoto, K., Ohmura, M., Naka, K., Hosokawa, K., Ikeda, Y. et al. (2006). Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat. Med. 12, 446-451.
-
(2006)
Nat. Med
, vol.12
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Takubo, K.4
Matsuoka, S.5
Miyamoto, K.6
Ohmura, M.7
Naka, K.8
Hosokawa, K.9
Ikeda, Y.10
-
55
-
-
84868632060
-
A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance
-
Ito, K., Carracedo, A., Weiss, D., Arai, F., Ala, U., Avigan, D. E., Schafer, Z. T., Evans, R. M., Suda, T., Lee, C.-H. et al. (2012). A PML–PPAR-δ pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance. Nat. Med. 18, 1350-1358.
-
(2012)
Nat. Med
, vol.18
, pp. 1350-1358
-
-
Ito, K.1
Carracedo, A.2
Weiss, D.3
Arai, F.4
Ala, U.5
Avigan, D.E.6
Schafer, Z.T.7
Evans, R.M.8
Suda, T.9
Lee, C.-H.10
-
56
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
Itoh, K., Wakabayashi, N., Katoh, Y., Ishii, T., Igarashi, K., Engel, J. D. and Yamamoto, M. (1999). Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev. 13, 76-86.
-
(1999)
Genes Dev
, vol.13
, pp. 76-86
-
-
Itoh, K.1
Wakabayashi, N.2
Katoh, Y.3
Ishii, T.4
Igarashi, K.5
Engel, J.D.6
Yamamoto, M.7
-
57
-
-
35548936968
-
A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche
-
Jang, Y.-Y. and Sharkis, S. J. (2007). A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche. Blood 110, 3056-3063.
-
(2007)
Blood
, vol.110
, pp. 3056-3063
-
-
Jang, Y.-Y.1
Sharkis, S.J.2
-
58
-
-
45049085873
-
Redox-based regulation of signal transduction: Principles, pitfalls, and promises
-
Janssen-Heininger, Y. M. W., Mossman, B. T., Heintz, N. H., Forman, H. J., Kalyanaraman, B., Finkel, T., Stamler, J. S., Rhee, S. G. and van der Vliet, A. (2008). Redox-based regulation of signal transduction: principles, pitfalls, and promises. Free Radic. Biol. Med. 45, 1-17.
-
(2008)
Free Radic. BiolMed
, vol.45
, pp. 1-17
-
-
Janssen-Heininger, Y.M.W.1
Mossman, B.T.2
Heintz, N.H.3
Forman, H.J.4
Kalyanaraman, B.5
Finkel, T.6
Stamler, J.S.7
Rhee, S.G.8
Van Der Vliet, A.9
-
59
-
-
84892598278
-
Antioxidant supplementation reduces genomic aberrations in human induced pluripotent stem cells
-
Ji, J., Sharma, V., Qi, S., Guarch, M. E., Zhao, P., Luo, Z., Fan, W., Wang, Y., Mbabaali, F., Neculai, D. et al. (2014). Antioxidant supplementation reduces genomic aberrations in human induced pluripotent stem cells. Stem Cell Rep. 2, 44-51.
-
(2014)
Stem Cell Rep
, vol.2
, pp. 44-51
-
-
Ji, J.1
Sharma, V.2
Qi, S.3
Guarch, M.E.4
Zhao, P.5
Luo, Z.6
Fan, W.7
Wang, Y.8
Mbabaali, F.9
Neculai, D.10
-
60
-
-
84887456727
-
Mitophagy in hematopoietic stem cells: The case for exploration
-
J oshi, A. and Kundu, M. (2013). Mitophagy in hematopoietic stem cells: the case for exploration. Autophagy 9, 1737-1749.
-
(2013)
Autophagy
, vol.9
, pp. 1737-1749
-
-
J Oshi, A.1
Kundu, M.2
-
61
-
-
84879858404
-
TXNIP maintains the hematopoietic cell pool by switching the function of p53 under oxidative stress
-
Jung, H., Kim, M. J., Kim, D. O., Kim, W. S., Yoon, S.-J., Park, Y.-J., Yoon, S. R., Kim, T.-D., Suh, H.-W., Yun, S. et al. (2013). TXNIP maintains the hematopoietic cell pool by switching the function of p53 under oxidative stress. Cell Metabol. 18, 75-85.
-
(2013)
Cell Metabol
, vol.18
, pp. 75-85
-
-
Jung, H.1
Kim, M.J.2
Kim, D.O.3
Kim, W.S.4
Yoon, S.-J.5
Park, Y.-J.6
Yoon, S.R.7
Kim, T.-D.8
Suh, H.-W.9
Yun, S.10
-
62
-
-
77953283847
-
AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species
-
Juntilla, M. M., Patil, V. D., Calamito, M., Joshi, R. P., Birnbaum, M. J. and Koretzky, G. A. (2010). AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species. Blood 115, 4030-4038.
-
(2010)
Blood
, vol.115
, pp. 4030-4038
-
-
Juntilla, M.M.1
Patil, V.D.2
Calamito, M.3
Joshi, R.P.4
Birnbaum, M.J.5
Koretzky, G.A.6
-
63
-
-
79961011901
-
Reactive oxygen species mediate adipocyte differentiation in mesenchymal stem cells
-
Kanda, Y., Hinata, T., Kang, S. W. and Watanabe, Y. (2011). Reactive oxygen species mediate adipocyte differentiation in mesenchymal stem cells. Life Sci. 89, 250-258.
-
(2011)
Life Sci
, vol.89
, pp. 250-258
-
-
Kanda, Y.1
Hinata, T.2
Kang, S.W.3
Watanabe, Y.4
-
64
-
-
58849156573
-
A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress
-
Kang, J., Gemberling, M., Nakamura, M., Whitby, F. G., Handa, H., Fairbrother, W. G. and Tantin, D. (2009). A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress. Genes Dev. 23, 208-222.
-
(2009)
Genes Dev
, vol.23
, pp. 208-222
-
-
Kang, J.1
Gemberling, M.2
Nakamura, M.3
Whitby, F.G.4
Handa, H.5
Fairbrother, W.G.6
Tantin, D.7
-
65
-
-
69249127963
-
Loss of ATM impairs proliferation of neural stem cells through oxidative stress-mediated p38 MAPK signaling
-
Kim, J, and Wong, P. K. Y. (2009). Loss of ATM impairs proliferation of neural stem cells through oxidative stress-mediated p38 MAPK signaling. Stem Cells 27, 1987-1998.
-
(2009)
Stem Cells
, vol.27
, pp. 1987-1998
-
-
Kim, J.1
Wong, P.K.Y.2
-
66
-
-
84891367550
-
Low production of reactive oxygen species and high DNA repair: Mechanism of radioresistance of prostate cancer stem cells
-
Kim, Y. S., Kang, M. J. and Cho, Y. M. (2013). Low production of reactive oxygen species and high DNA repair: mechanism of radioresistance of prostate cancer stem cells. Anticancer Res. 33, 4469-4474.
-
(2013)
Anticancer Res
, vol.33
, pp. 4469-4474
-
-
Kim, Y.S.1
Kang, M.J.2
Cho, Y.M.3
-
67
-
-
24744469490
-
SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stress
-
Kobayashi, Y., Furukawa-Hibi, Y., Chen, C., Horio, Y., Isobe, K., Ikeda, K. and Motoyama, N. (2005). SIRT1 is critical regulator of FOXO-mediated transcription in response to oxidative stress. Int. J. Mol. Med. 16, 237-243.
-
(2005)
Int. J. Mol. Med
, vol.16
, pp. 237-243
-
-
Kobayashi, Y.1
Furukawa-Hibi, Y.2
Chen, C.3
Horio, Y.4
Isobe, K.5
Ikeda, K.6
Motoyama, N.7
-
68
-
-
84871001227
-
Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells
-
Kocabas, F., Zheng, J., Thet, S., Copeland, N. G., Jenkins, N. A., DeBerardinis, R. J., Zhang, C. and Sadek, A. H. (2012). Meis1 regulates the metabolic phenotype and oxidant defense of hematopoietic stem cells. Blood 120, 4963-4972.
-
(2012)
Blood
, vol.120
, pp. 4963-4972
-
-
Kocabas, F.1
Zheng, J.2
Thet, S.3
Copeland, N.G.4
Jenkins, N.A.5
Deberardinis, R.J.6
Zhang, C.7
Sadek, A.H.8
-
69
-
-
84886860116
-
TET enzymes, TDG and the dynamics of DNA demethylation
-
Kohli, R. M. and Zhang, Y. (2013). TET enzymes, TDG and the dynamics of DNA demethylation. Nature 502, 472-479.
-
(2013)
Nature
, vol.502
, pp. 472-479
-
-
Kohli, R.M.1
Zhang, Y.2
-
70
-
-
84886947010
-
Arteriolar niches maintain haematopoietic stem cell quiescence
-
Kunisaki, Y., Bruns, I., Scheiermann, C., Ahmed, J., Pinho, S., Zhang, D., Mizoguchi, T, Wei, Q, Lucas, D, Ito, K. et al. (2013). Arteriolar niches maintain haematopoietic stem cell quiescence. Nature 502, 637-643.
-
(2013)
Nature
, vol.502
, pp. 637-643
-
-
Kunisaki, Y.1
Bruns, I.2
Scheiermann, C.3
Ahmed, J.4
Pinho, S.5
Zhang, D.6
Mizoguchi, T.7
Wei, Q.8
Lucas, D.9
Ito, K.10
-
71
-
-
84875143073
-
BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells
-
Lagadinou, E. D., Sach, A., Callahan, K., Rossi, R. M., Neering, S. J., Minhajuddin, M., Ashton, J. M., Pei, S., Grose, V., O’Dwyer, K. M. et al. (2013). BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells. Cell Stem Cell 12, 329-341.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 329-341
-
-
Lagadinou, E.D.1
Sach, A.2
Callahan, K.3
Rossi, R.M.4
Neering, S.J.5
Minhajuddin, M.6
Ashton, J.M.7
Pei, S.8
Grose, V.9
O’dwyer, K.M.10
-
72
-
-
73749085674
-
When a theory of aging ages badly
-
Lapointe, J. and Hekimi, S. (2010). When a theory of aging ages badly. Cell. Mol. Life Sci. 67, 1-8.
-
(2010)
Cell. Mol. Life Sci
, vol.67
, pp. 1-8
-
-
Lapointe, J.1
Hekimi, S.2
-
73
-
-
78650968492
-
Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/ Akt-dependant manner
-
Le Belle, J. E., Orozco, N. M., Paucar, A. A., Saxe, J. P., Mottahedeh, J., Pyle, A. D., Wu, H. and Kornblum, H. I. (2011). Proliferative neural stem cells have high endogenous ROS levels that regulate self-renewal and neurogenesis in a PI3K/ Akt-dependant manner. Cell Stem Cell 8, 59-71.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 59-71
-
-
Le Belle, J.E.1
Orozco, N.M.2
Paucar, A.A.3
Saxe, J.P.4
Mottahedeh, J.5
Pyle, A.D.6
Wu, H.7
Kornblum, H.I.8
-
74
-
-
0032191655
-
Inhibition of p53-dependent apoptosis by the KIT tyrosine kinase: Regulation of mitochondrial permeability transition and reactive oxygen species generation
-
Lee, J. M. (1998). Inhibition of p53-dependent apoptosis by the KIT tyrosine kinase: regulation of mitochondrial permeability transition and reactive oxygen species generation. Oncogene 17, 1653-1662.
-
(1998)
Oncogene
, vol.17
, pp. 1653-1662
-
-
Lee, J.M.1
-
75
-
-
0037036358
-
Reversible inactivation of the tumor suppressor PTEN by H2O2
-
Lee, S.-R., Yang, K.-S., Kwon, J., Lee, C., Jeong, W. and Rhee, S. G. (2002). Reversible inactivation of the tumor suppressor PTEN by H2O2. J. Biol. Chem. 277, 20336-20342.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 20336-20342
-
-
Lee, S.-R.1
Yang, K.-S.2
Kwon, J.3
Lee, C.4
Jeong, W.5
Rhee, S.G.6
-
76
-
-
0037673984
-
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells
-
Lessard, J. and Sauvageau, G. (2003). Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells. Nature 423, 255-260.
-
(2003)
Nature
, vol.423
, pp. 255-260
-
-
Lessard, J.1
Sauvageau, G.2
-
77
-
-
84897040644
-
Stem cells, redox signaling, and stem cell aging.
-
Liang, R. and Ghaffari, S. (2014). Stem cells, redox signaling, and stem cell aging. Antioxid. Redox Signal. 20, 1902-1916.
-
(2014)
Antioxid. Redox Signal
, vol.20
, pp. 1902-1916
-
-
Liang, R.1
Ghaffari, S.2
-
78
-
-
77955499804
-
Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxiainducible factor 1alpha
-
Lim, J.-H., Lee, Y.-M., Chun, Y.-S., Chen, J., Kim, J.-E. and Park, J.-W. (2010). Sirtuin 1 modulates cellular responses to hypoxia by deacetylating hypoxiainducible factor 1alpha. Mol. Cell 38, 864-878.
-
(2010)
Mol. Cell
, vol.38
, pp. 864-878
-
-
Lim, J.-H.1
Lee, Y.-M.2
Chun, Y.-S.3
Chen, J.4
Kim, J.-E.5
Park, J.-W.6
-
79
-
-
27944474377
-
Redox-dependent transcriptional regulation
-
Liu, H., Colavitti, R., Rovira, I. I. and Finkel, T. (2005). Redox-dependent transcriptional regulation. Circ. Res. 97, 967-974.
-
(2005)
Circ. Res
, vol.97
, pp. 967-974
-
-
Liu, H.1
Colavitti, R.2
Rovira, I.I.3
Finkel, T.4
-
80
-
-
58049216794
-
(2009a). p53 regulates hematopoietic stem cell quiescence
-
Liu, Y., Elf, S. E., Miyata, Y., Sashida, G., Liu, Y., Huang, G., Di Giandomenico, S., Lee, J. M., Deblasio, A., Menendez, S. et al. (2009a). p53 regulates hematopoietic stem cell quiescence. Cell Stem Cell 4, 37-48.
-
Cell Stem Cell
, vol.4
, pp. 37-48
-
-
Liu, Y.1
Elf, S.E.2
Miyata, Y.3
Sashida, G.4
Liu, Y.5
Huang, G.6
Di Giandomenico, S.7
Lee, J.M.8
Deblasio, A.9
Menendez, S.10
-
81
-
-
67349156082
-
Bmi1 regulates mitochondrial function and the DNA damage response pathway
-
Liu, J., Cao, L., Chen, J., Song, S., Lee, I. H., Quijano, C., Liu, H., Keyvanfar, K., Chen, H., Cao, L.-Y. et al. (2009b). Bmi1 regulates mitochondrial function and the DNA damage response pathway. Nature 459, 387-392.
-
(2009)
Nature
, vol.459
, pp. 387-392
-
-
Liu, J.1
Cao, L.2
Chen, J.3
Song, S.4
Lee, I.H.5
Quijano, C.6
Liu, H.7
Keyvanfar, K.8
Chen, H.9
Cao, L.-Y.10
-
82
-
-
81855207310
-
Oxidants, metabolism, and stem cell biology
-
Liu, J., Cao, L. and Finkel, T. (2011). Oxidants, metabolism, and stem cell biology. Free Radic. Biol. Med. 51, 2158-2162.
-
(2011)
Free Radic. Biol. Med
, vol.51
, pp. 2158-2162
-
-
Liu, J.1
Cao, L.2
Finkel, T.3
-
83
-
-
79953000879
-
Mitochondrial function controls proliferation and early differentiation potential of embryonic stem cells
-
Mandal, S., Lindgren, A. G., Srivastava, A. S., Clark, A. T. and Banerjee, U. (2011). Mitochondrial function controls proliferation and early differentiation potential of embryonic stem cells. Stem Cells 29, 486-495.
-
(2011)
Stem Cells
, vol.29
, pp. 486-495
-
-
Mandal, S.1
Lindgren, A.G.2
Srivastava, A.S.3
Clark, A.T.4
Banerjee, U.5
-
84
-
-
84887320216
-
A role for reactive oxygen species in JAK2V617F myeloproliferative neoplasm progression.
-
Marty, C., Lacout, C., Droin, N., Le Couedic J. -P., Ribrag, V., Solary, E., Vainchenker, W., Villeval, J.-L. and Plo, I. (2013). A role for reactive oxygen species in JAK2V617F myeloproliferative neoplasm progression. Leukemia 27, 2187-2195.
-
(2013)
Leukemia
, vol.27
, pp. 2187-2195
-
-
Marty, C.1
Lacout, C.2
Droin, N.3
Le Couedic , J.-P.4
Ribrag, V.5
Solary, E.6
Vainchenker, W.7
Villeval, J.-L.8
Plo, I.9
-
85
-
-
84860528235
-
The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells
-
Maryanovich, M., Oberkovitz, G., Niv, H., Vorobiyov, L., Zaltsman, Y., Brenner, O., Lapidot, T., Jung, S. and Gross, A. (2012). The ATM-BID pathway regulates quiescence and survival of haematopoietic stem cells. Nat. Cell Biol. 14, 535-541.
-
(2012)
Nat. Cell Biol
, vol.14
, pp. 535-541
-
-
Maryanovich, M.1
Oberkovitz, G.2
Niv, H.3
Vorobiyov, L.4
Zaltsman, Y.5
Brenner, O.6
Lapidot, T.7
Jung, S.8
Gross, A.9
-
86
-
-
84901281295
-
The histone methyltransferase activity of MLL1 is dispensable for hematopoiesis and leukemogenesis
-
Mishra, B. P., Zaffuto, K. M., Artinger, E. L., Org, T., Mikkola, H. K. A., Cheng, C., Djabali, M. and Ernst, P. (2014). The histone methyltransferase activity of MLL1 is dispensable for hematopoiesis and leukemogenesis. Cell Rep. 7, 1239-1247.
-
(2014)
Cell Rep
, vol.7
, pp. 1239-1247
-
-
Mishra, B.P.1
Zaffuto, K.M.2
Artinger, E.L.3
Org, T.4
Mikkola, H.K.A.5
Cheng, C.6
Djabali, M.7
Ernst, P.8
-
87
-
-
34249882777
-
Foxo3a is essential for maintenance of the hematopoietic stem cell pool
-
Miyamoto, K., Araki, K. Y., Naka, K., Arai, F., Takubo, K., Yamazaki, S., Matsuoka, S., Miyamoto, T., Ito, K., Ohmura, M. et al. (2007). Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell 1, 101-112.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 101-112
-
-
Miyamoto, K.1
Araki, K.Y.2
Naka, K.3
Arai, F.4
Takubo, K.5
Yamazaki, S.6
Matsuoka, S.7
Miyamoto, T.8
Ito, K.9
Ohmura, M.10
-
88
-
-
0242667922
-
Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation
-
Molofsky, A. V., Pardal, R., Iwashita, T., Park, I.-K., Clarke, M. F. and Morrison, S. J. (2003). Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425, 962-967.
-
(2003)
Nature
, vol.425
, pp. 962-967
-
-
Molofsky, A.V.1
Pardal, R.2
Iwashita, T.3
Park, I.-K.4
Clarke, M.F.5
Morrison, S.J.6
-
89
-
-
79960064353
-
Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation
-
Moran-Crusio, K., Reavie, L., Shih, A., Abdel-Wahab, O., Ndiaye-Lobry, D., Lobry, C., Figueroa, M. E., Vasanthakumar, A., Patel, J., Zhao, X. et al. (2011). Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation. Cancer Cell 20, 11-24.
-
(2011)
Cancer Cell
, vol.20
, pp. 11-24
-
-
Moran-Crusio, K.1
Reavie, L.2
Shih, A.3
Abdel-Wahab, O.4
Ndiaye-Lobry, D.5
Lobry, C.6
Figueroa, M.E.7
Vasanthakumar, A.8
Patel, J.9
Zhao, X.10
-
90
-
-
84878846051
-
ROS are required for mouse spermatogonial stem cell self-renewal
-
Morimoto, H., Iwata, K., Ogonuki, N., Inoue, K., Atsuo, O., Kanatsu-Shinohara, M., Morimoto, T., Yabe-Nishimura, C. and Shinohara, T. (2013). ROS are required for mouse spermatogonial stem cell self-renewal. Cell Stem Cell 12, 774-786.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 774-786
-
-
Morimoto, H.1
Iwata, K.2
Ogonuki, N.3
Inoue, K.4
Atsuo, O.5
Kanatsu-Shinohara, M.6
Morimoto, T.7
Yabe-Nishimura, C.8
Shinohara, T.9
-
91
-
-
7244253081
-
Nrf2-Keap1 defines a physiologically important stress response mechanism
-
Motohashi, H. and Yamamoto, M. (2004). Nrf2-Keap1 defines a physiologically important stress response mechanism. Trends Mol. Med. 10, 549-557.
-
(2004)
Trends Mol. Med
, vol.10
, pp. 549-557
-
-
Motohashi, H.1
Yamamoto, M.2
-
92
-
-
1342264308
-
Mammalian SIRT1 represses forkhead transcription factors
-
Motta, M. C., Divecha, N., Lemieux, M., Kamel, C., Chen, D., Gu, W., Bultsma, Y., McBurney, M. and Guarente, L. (2004). Mammalian SIRT1 represses forkhead transcription factors. Cell 116, 551-563.
-
(2004)
Cell
, vol.116
, pp. 551-563
-
-
Motta, M.C.1
Divecha, N.2
Lemieux, M.3
Kamel, C.4
Chen, D.5
Gu, W.6
Bultsma, Y.7
McBurney, M.8
Guarente, L.9
-
93
-
-
84880517634
-
he NAD(+)/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling.
-
Mouchiroud, L., Houtkooper, R. H., Moullan, N., Katsyuba, E., Ryu, D., Canto C., Mottis A., Jo Y.-S., Viswanathan M., Schoonjans K. et al. (2013). The NAD(+)/sirtuin pathway modulates longevity through activation of mitochondrial UPR and FOXO signaling. Cell 154, 430-441.
-
(2013)
Cell
, vol.54
, pp. 30-441.
-
-
Mouchiroud, L.1
Houtkooper, R.H.2
Moullan, N.3
Katsyuba, E.4
Ryu, D.5
Cantoó, C.6
Mottis, A.7
Jo, Y.-S.8
Viswanathan, M.9
Schoonjans, K.10
-
94
-
-
0346749513
-
Glutaredoxin exerts an antiapoptotic effect by regulating the redox state of Akt
-
Murata, H., Ihara, Y., Nakamura, H., Yodoi, J., Sumikawa, K. and Kondo, T. (2003). Glutaredoxin exerts an antiapoptotic effect by regulating the redox state of Akt. J. Biol. Chem. 278, 50226-50233.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 50226-50233
-
-
Murata, H.1
Ihara, Y.2
Nakamura, H.3
Yodoi, J.4
Sumikawa, K.5
Kondo, T.6
-
95
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
Murphy, M. P. (2009). How mitochondria produce reactive oxygen species. Biochem. J. 417, 1-13.
-
(2009)
Biochem. J
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
96
-
-
79953762174
-
Unraveling the biological roles of reactive oxygen species
-
Murphy, M. P., Holmgren, A., Larsson, N.-G., Halliwell, B., Chang, C. J., Kalyanaraman, B., Rhee, S. G., Thornalley, P. J., Partridge, L., Gems, D. et al. (2011). Unraveling the biological roles of reactive oxygen species. Cell Metabol. 13, 361-366.
-
(2011)
Cell Metabol
, vol.13
, pp. 361-366
-
-
Murphy, M.P.1
Holmgren, A.2
Larsson, N.-G.3
Halliwell, B.4
Chang, C.J.5
Kalyanaraman, B.6
Rhee, S.G.7
Thornalley, P.J.8
Partridge, L.9
Gems, D.10
-
97
-
-
39349106325
-
Differentiation of embryonic stem cells to clinically relevant populations: Lessons from embryonic development
-
Murry, C. E. and Keller, G. (2008). Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell 132, 661-680.
-
(2008)
Cell
, vol.132
, pp. 661-680
-
-
Murry, C.E.1
Keller, G.2
-
98
-
-
78649811793
-
Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells
-
Nakada, D., Saunders, T. L. and Morrison, S. J. (2010). Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells. Nature 468, 653-658.
-
(2010)
Nature
, vol.468
, pp. 653-658
-
-
Nakada, D.1
Saunders, T.L.2
Morrison, S.J.3
-
99
-
-
84876931396
-
Beyond oxidative stress: An immunologist’s guide to reactive oxygen species
-
Nathan, C. and Cunningham-Bussel, A. (2013). Beyond oxidative stress: an immunologist’s guide to reactive oxygen species. Nat. Rev. Immunol. 13, 349-361.
-
(2013)
Nat. Rev. Immunol
, vol.13
, pp. 349-361
-
-
Nathan, C.1
Cunningham-Bussel, A.2
-
100
-
-
79955698235
-
Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging
-
Norddahl, G. L., Pronk, C. J., Wahlestedt, M., Sten, G., Nygren, J. M., Ugale, A., Sigvardsson, M. and Bryder, D. (2011). Accumulating mitochondrial DNA mutations drive premature hematopoietic aging phenotypes distinct from physiological stem cell aging. Cell Stem Cell 8, 499-510.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 499-510
-
-
Norddahl, G.L.1
Pronk, C.J.2
Wahlestedt, M.3
Sten, G.4
Nygren, J.M.5
Ugale, A.6
Sigvardsson, M.7
Bryder, D.8
-
101
-
-
84905921360
-
Glucose and glutamine metabolism regulate human hematopoietic stem cell lineage specification
-
Oburoglu, L., Tardito, S., Fritz, V., de Barros, S. C., Merida, P., Craveiro, M., Mamede, J., Cretenet, G., Mongellaz, C., An, X. et al. (2014). Glucose and glutamine metabolism regulate human hematopoietic stem cell lineage specification. Cell Stem Cell p15, 169-184.
-
(2014)
Cell Stem Cell
, vol.p15
, pp. 169-184
-
-
Oburoglu, L.1
Tardito, S.2
Fritz, V.3
De Barros, S.C.4
Merida, P.5
Craveiro, M.6
Mamede, J.7
Cretenet, G.8
Mongellaz, C.9
An, X.10
-
102
-
-
84898031861
-
SIRT1 positively regulates autophagy and mitochondria function in embryonic stem cells under oxidative stress
-
Ou, X., Lee, M. R., Huang, X., Messina-Graham, S. and Broxmeyer, H. E. (2014). SIRT1 positively regulates autophagy and mitochondria function in embryonic stem cells under oxidative stress. Stem Cells 32, 1183-1194.
-
(2014)
Stem Cells
, vol.32
, pp. 1183-1194
-
-
Ou, X.1
Lee, M.R.2
Huang, X.3
Messina-Graham, S.4
Broxmeyer, H.E.5
-
103
-
-
70349446465
-
Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation
-
Owusu-Ansah, E. and Banerjee, U. (2009). Reactive oxygen species prime Drosophila haematopoietic progenitors for differentiation. Nature 461, 537-541.
-
(2009)
Nature
, vol.461
, pp. 537-541
-
-
Owusu-Ansah, E.1
Banerjee, U.2
-
104
-
-
70350497348
-
FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis
-
Paik, J.-h., Ding, Z., Narurkar, R., Ramkissoon, S., Muller, F., Kamoun, W. S., Chae, S.-S., Zheng, H., Ying, H., Mahoney, J. et al. (2009). FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis. Cell Stem Cell 5, 540-553.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 540-553
-
-
Paik, J.-H.1
Ding, Z.2
Narurkar, R.3
Ramkissoon, S.4
Muller, F.5
Kamoun, W.S.6
Chae, S.-S.7
Zheng, H.8
Ying, H.9
Mahoney, J.10
-
105
-
-
0030746981
-
Redox state regulates binding of p53 to sequence-specific DNA, but not to non-specific or mismatched DNA
-
Parks, D., Bolinger, R. and Mann, K. (1997). Redox state regulates binding of p53 to sequence-specific DNA, but not to non-specific or mismatched DNA. Nucleic Acids Res. 25, 1289-1295.
-
(1997)
Nucleic Acids Res
, vol.25
, pp. 1289-1295
-
-
Parks, D.1
Bolinger, R.2
Mann, K.3
-
106
-
-
84888362641
-
Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells
-
P ei, S., Minhajuddin, M., Callahan, K. P., Balys, M., Ashton, J. M., Neering, S. J., Lagadinou, E. D., Corbett, C., Ye, H., Liesveld, J. L. et al. (2013). Targeting aberrant glutathione metabolism to eradicate human acute myelogenous leukemia cells. J. Biol. Chem. 288, 33542-33558.
-
(2013)
J. Biol. Chem
, vol.288
, pp. 33542-33558
-
-
P Ei, S.1
Minhajuddin, M.2
Callahan, K.P.3
Balys, M.4
Ashton, J.M.5
Neering, S.J.6
Lagadinou, E.D.7
Corbett, C.8
Ye, H.9
Liesveld, J.L.10
-
107
-
-
0030930366
-
A model for p53-induced apoptosis
-
Polyak, K., Xia, Y., Zweier, J. L., Kinzler, K.W. and Vogelstein, B. (1997). A model for p53-induced apoptosis. Nature 389, 300-305.
-
(1997)
Nature
, vol.389
, pp. 300-305
-
-
Polyak, K.1
Xia, Y.2
Zweier, J.L.3
Kinzler, K.W.4
Vogelstein, B.5
-
108
-
-
77951002352
-
The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells
-
Prigione, A., Fauler, B., Lurz, R., Lehrach, H. and Adjaye, J. (2010). The senescence-related mitochondrial/oxidative stress pathway is repressed in human induced pluripotent stem cells. Stem Cells 28, 721-733.
-
(2010)
Stem Cells
, vol.28
, pp. 721-733
-
-
Prigione, A.1
Fauler, B.2
Lurz, R.3
Lehrach, H.4
Adjaye, J.5
-
109
-
-
70350506802
-
FoxO3 regulates neural stem cell homeostasis
-
Renault, V. M., Rafalski, V. A., Morgan, A. A., Salih, D. A. M., Brett, J. O., Webb, A. E., Villeda, S. A., Thekkat, P. U., Guillerey, C., Denko, N. C. et al. (2009). FoxO3 regulates neural stem cell homeostasis. Cell Stem Cell 5, 527-539.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 527-539
-
-
Renault, V.M.1
Rafalski, V.A.2
Morgan, A.A.3
Salih, D.A.M.4
Brett, J.O.5
Webb, A.E.6
Villeda, S.A.7
Thekkat, P.U.8
Guillerey, C.9
Denko, N.C.10
-
110
-
-
84904206273
-
ging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells.
-
Rimmele P., Bigarella, C. L., Liang, R., Izac, B., Dieguez-Gonzalez, R., Barbet, G., Donovan, M., Brugnara, C., Blander, J. M., Sinclair, D. A. et al. (2014). Aging-like phenotype and defective lineage specification in SIRT1-deleted hematopoietic stem and progenitor cells. Stem Cell Rep. 3, 44-59.
-
(2014)
Stem Cell Rep.
, pp. 4-59
-
-
Rimmele, P.1
Bigarella, C.L.2
Liang, R.3
Izac, B.4
Dieguez-Gonzalez, R.5
Barbet, G.6
Donovan, M.7
Brugnara, C.8
Blander, J.M.9
Sinclair, D.A.10
-
111
-
-
84879130009
-
Aldolase sequestersWASP and affects WASP/Arp2/3-stimulated actin dynamics
-
R itterson Lew, C. and Tolan, D. R. (2013). Aldolase sequestersWASP and affects WASP/Arp2/3-stimulated actin dynamics. J. Cell. Biochem. 114, 1928-1939.
-
(2013)
J. Cell. Biochem
, vol.114
, pp. 1928-1939
-
-
R Itterson Lew, C.1
Tolan, D.R.2
-
112
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
Rodgers, J. T., Lerin, C., Haas, W., Gygi, S. P., Spiegelman, B. M. and Puigserver, P. (2005). Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434, 113-118.
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
113
-
-
84870409504
-
Production of reactive oxygen species by multipotent stromal cells/mesenchymal stem cells upon exposure to fas ligand
-
R odrigues, M., Turner, O., Stolz, D., Griffith, L. G. and Wells, A. (2012). Production of reactive oxygen species by multipotent stromal cells/mesenchymal stem cells upon exposure to fas ligand. Cell Transplant. 21, 2171-2187.
-
(2012)
Cell Transplant
, vol.21
, pp. 2171-2187
-
-
R Odrigues, M.1
Turner, O.2
Stolz, D.3
Griffith, L.G.4
Wells, A.5
-
114
-
-
85027932030
-
HIF-2α protects human hematopoietic stem/progenitors and acute myeloid leukemic cells from apoptosis induced by endoplasmic reticulum stress
-
R ouault-Pierre, K., Lopez-Onieva, L., Foster, K., Anjos-Afonso, F., Lamrissi- Garcia, I., Serrano-Sanchez, M., Mitter, R., Ivanovic, Z., de Verneuil, H., Gribben, J. et al. (2013). HIF-2α protects human hematopoietic stem/progenitors and acute myeloid leukemic cells from apoptosis induced by endoplasmic reticulum stress. Cell Stem Cell 13, 549-563.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 549-563
-
-
R Ouault-Pierre, K.1
Lopez-Onieva, L.2
Foster, K.3
Anjos-Afonso, F.4
Lamrissi- Garcia, I.5
Serrano-Sanchez, M.6
Mitter, R.7
Ivanovic, Z.8
De Verneuil, H.9
Gribben, J.10
-
115
-
-
28644447272
-
The antioxidant function of the p53 tumor suppressor.
-
S ablina, A. A., Budanov, A. V., Ilyinskaya, G. V., Agapova, L. S., Kravchenko, J. E. and Chumakov, P. M. (2005). The antioxidant function of the p53 tumor suppressor. Nat. Med. 11, 1306-1313.
-
(2005)
Nat. Med
, vol.11
, pp. 1306-1313
-
-
S Ablina, A.A.1
Budanov, A.V.2
Ilyinskaya, G.V.3
Agapova, L.S.4
Kravchenko, J.E.5
Chumakov, P.M.6
-
116
-
-
77749317560
-
Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML
-
S aito, Y., Uchida, N., Tanaka, S., Suzuki, N., Tomizawa-Murasawa, M., Sone, A., Najima, Y., Takagi, S., Aoki, Y., Wake, A. et al. (2010). Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML. Nat. Biotechnol. 28, 275-280.
-
(2010)
Nat. Biotechnol
, vol.28
, pp. 275-280
-
-
S Aito, Y.1
Uchida, N.2
Tanaka, S.3
Suzuki, N.4
Tomizawa-Murasawa, M.5
Sone, A.6
Najima, Y.7
Takagi, S.8
Aoki, Y.9
Wake, A.10
-
117
-
-
0032080283
-
Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1
-
Saitoh, M., Nishitoh, H., Fujii, M., Takeda, K., Tobiume, K., Sawada, Y., Kawabata, M., Miyazono, K. and Ichijo, H. (1998). Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. E MBO J. 17, 2596-2606.
-
(1998)
E MBO J
, vol.17
, pp. 2596-2606
-
-
Saitoh, M.1
Nishitoh, H.2
Fujii, M.3
Takeda, K.4
Tobiume, K.5
Sawada, Y.6
Kawabata, M.7
Miyazono, K.8
Ichijo, H.9
-
118
-
-
0038411479
-
Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate
-
S almeen, A., Andersen, J. N., Myers, M. P., Meng, T.-C., Hinks, J. A., Tonks, N. K. and Barford, D. (2003). Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate. Nature 423, 769-773.
-
(2003)
Nature
, vol.423
, pp. 769-773
-
-
S Almeen, A.1
Andersen, J.N.2
Myers, M.P.3
Meng, T.-C.4
Hinks, J.A.5
Tonks, N.K.6
Barford, D.7
-
119
-
-
28244469041
-
Redox regulation of the nutrientsensitive raptor-mTOR pathway and complex
-
S arbassov, D. D. and Sabatini, D. M. (2005). Redox regulation of the nutrientsensitive raptor-mTOR pathway and complex. J. Biol. Chem. 280, 39505-39509.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 39505-39509
-
-
S Arbassov, D.D.1
Sabatini, D.M.2
-
120
-
-
57649134966
-
Mitochondrial metabolism modulates differentiation and teratoma formation capacity in mouse embryonic stem cells
-
S chieke, S. M., Ma, M., Cao, L., McCoy, J. P., Liu, C., Hensel, N. F., Barrett, A. J., Boehm, M. and Finkel, T. (2008). Mitochondrial metabolism modulates differentiation and teratoma formation capacity in mouse embryonic stem cells. J. Biol. Chem. 283, 28506-28512.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 28506-28512
-
-
S Chieke, S.M.1
Ma, M.2
Cao, L.3
McCoy, J.P.4
Liu, C.5
Hensel, N.F.6
Barrett, A.J.7
Boehm, M.8
Finkel, T.9
-
121
-
-
84873608154
-
Mechanisms that regulate stem cell aging and life span
-
S igner, R. A. J. and Morrison, S. J. (2013). Mechanisms that regulate stem cell aging and life span. Cell Stem Cell 12, 152-165.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 152-165
-
-
S Igner, R.A.J.1
Morrison, S.J.2
-
122
-
-
77956205122
-
The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche
-
S imsek, T., Kocabas, F., Zheng, J., Deberardinis, R. J., Mahmoud, A. I., Olson, E. N., Schneider, J. W., Zhang, C. C. and Sadek, H. A. (2010). The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. Cell Stem Cell 7, 380-390.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 380-390
-
-
S Imsek, T.1
Kocabas, F.2
Zheng, J.3
Deberardinis, R.J.4
Mahmoud, A.I.5
Olson, E.N.6
Schneider, J.W.7
Zhang, C.C.8
Sadek, H.A.9
-
123
-
-
84879591586
-
Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance
-
S ingh, S. K., Williams, C. A., Klarmann, K., Burkett, S. S., Keller, J. R. and Oberdoerffer, P. (2013). Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance. J. Exp. Med. 210, 987-1001.
-
(2013)
J. Exp. Med
, vol.210
, pp. 987-1001
-
-
S Ingh, S.K.1
Williams, C.A.2
Klarmann, K.3
Burkett, S.S.4
Keller, J.R.5
Oberdoerffer, P.6
-
124
-
-
80052340065
-
Role of thioredoxin 1 and thioredoxin 2 on proliferation of human adipose tissue-derived mesenchymal stem cells
-
S ong, J. S., Cho, H. H., Lee, B.-J., Bae, Y. C. and Jung, J. S. (2011). Role of thioredoxin 1 and thioredoxin 2 on proliferation of human adipose tissue-derived mesenchymal stem cells. Stem Cells Dev. 20, 1529-1537.
-
(2011)
Stem Cells Dev
, vol.20
, pp. 1529-1537
-
-
S Ong, J.S.1
Cho, H.H.2
Lee, B.-J.3
Bae, Y.C.4
Jung, J.S.5
-
125
-
-
0028973482
-
Requirement for generation of H2O2 for platelet-derived growth factor signal transduction
-
S undaresan, M., Yu, Z.-X., Ferrans, V. J., Irani, K. and Finkel, T. (1995). Requirement for generation of H2O2 for platelet-derived growth factor signal transduction. Science 270, 296-299.
-
(1995)
Science
, vol.270
, pp. 296-299
-
-
S Undaresan, M.1
Yu, Z.-X.2
Ferrans, V.J.3
Irani, K.4
Finkel, T.5
-
126
-
-
84903954689
-
A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation
-
S utendra, G., Kinnaird, A., Dromparis, P., Paulin, R., Stenson, T. H., Haromy, A., Hashimoto, K., Zhang, N., Flaim, E. and Michelakis, E. D. (2014). A nuclear pyruvate dehydrogenase complex is important for the generation of acetyl-CoA and histone acetylation. Cell 158, 84-97.
-
(2014)
Cell
, vol.158
, pp. 84-97
-
-
S Utendra, G.1
Kinnaird, A.2
Dromparis, P.3
Paulin, R.4
Stenson, T.H.5
Haromy, A.6
Hashimoto, K.7
Zhang, N.8
Flaim, E.9
Michelakis, E.D.10
-
127
-
-
63349087445
-
Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation
-
T ahara, E. B., Navarete, F. D. T. and Kowaltowski, A. J. (2009). Tissue-, substrate-, and site-specific characteristics of mitochondrial reactive oxygen species generation. Free Radic. Biol. Med. 46, 1283-1297.
-
(2009)
Free Radic. Biol. Med
, vol.46
, pp. 1283-1297
-
-
T Ahara, E.B.1
Navarete, F.D.T.2
Kowaltowski, A.J.3
-
128
-
-
66149146320
-
Conversion of 5- methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1
-
Tahiliani, M., Koh, K. P., Shen, Y., Pastor, W. A., Bandukwala, H., Brudno, Y., Agarwal, S., Iyer, L. M., Liu, D. R., Aravind, L. et al. (2009). Conversion of 5- methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1. Science 324, 930-935.
-
(2009)
Science
, vol.324
, pp. 930-935
-
-
Tahiliani, M.1
Koh, K.P.2
Shen, Y.3
Pastor, W.A.4
Bandukwala, H.5
Brudno, Y.6
Agarwal, S.7
Iyer, L.M.8
Liu, D.R.9
Aravind, L.10
-
129
-
-
84894414901
-
Mortalin and DJ-1 coordinately regulate hematopoietic stem cell function through the control of oxidative stress
-
Tai-Nagara, I., Matsuoka, S., Ariga, H. and Suda, T. (2014). Mortalin and DJ-1 coordinately regulate hematopoietic stem cell function through the control of oxidative stress. Blood 123, 41-50.
-
(2014)
Blood
, vol.123
, pp. 41-50
-
-
Tai-Nagara, I.1
Matsuoka, S.2
Ariga, H.3
Suda, T.4
-
130
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi, K. and Yamanaka, S. (2006). Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126, 663-676.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
131
-
-
77956217067
-
Regulation of the HIF-1alpha level is essential for hematopoietic stem cells
-
Takubo, K., Goda, N., Yamada, W., Iriuchishima, H., Ikeda, E., Kubota, Y., Shima, H., Johnson, R. S., Hirao, A., Suematsu, M. et al. (2010). Regulation of the HIF-1alpha level is essential for hematopoietic stem cells. Cell Stem Cell 7, 391-402.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 391-402
-
-
Takubo, K.1
Goda, N.2
Yamada, W.3
Iriuchishima, H.4
Ikeda, E.5
Kubota, Y.6
Shima, H.7
Johnson, R.S.8
Hirao, A.9
Suematsu, M.10
-
132
-
-
84872011926
-
Regulation of glycolysis by pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells
-
Takubo, K., Nagamatsu, G., Kobayashi, C. I., Nakamura-Ishizu, A., Kobayashi, H., Ikeda, E., Goda, N., Rahimi, Y., Johnson, R. S., Soga, T. et al. (2013). Regulation of glycolysis by pdk functions as a metabolic checkpoint for cell cycle quiescence in hematopoietic stem cells. Cell Stem Cell 12, 49-61.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 49-61
-
-
Takubo, K.1
Nagamatsu, G.2
Kobayashi, C.I.3
Nakamura-Ishizu, A.4
Kobayashi, H.5
Ikeda, E.6
Goda, N.7
Rahimi, Y.8
Johnson, R.S.9
Soga, T.10
-
133
-
-
0037711685
-
Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice
-
TeKippe, M., Harrison, D. E. and Chen, J. (2003). Expansion of hematopoietic stem cell phenotype and activity in Trp53-null mice. Exp. Hematol. 31, 521-527.
-
(2003)
Exp. Hematol
, vol.31
, pp. 521-527
-
-
Tekippe, M.1
Harrison, D.E.2
Chen, J.3
-
134
-
-
84872048038
-
Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes
-
Tohyama, S., Hattori, F., Sano, M., Hishiki, T., Nagahata, Y., Matsuura, T., Hashimoto, H., Suzuki, T., Yamashita, H., Satoh, Y. et al. (2012). Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes. Cell Stem Cell 12, 127-137.
-
(2012)
Cell Stem Cell
, vol.12
, pp. 127-137
-
-
Tohyama, S.1
Hattori, F.2
Sano, M.3
Hishiki, T.4
Nagahata, Y.5
Matsuura, T.6
Hashimoto, H.7
Suzuki, T.8
Yamashita, H.9
Satoh, Y.10
-
135
-
-
0025852479
-
Modulation of transcription factor NFkappa B binding activity by oxidation-reduction in vitro
-
Toledano, M. B. and Leonard, W. J. (1991). Modulation of transcription factor NFkappa B binding activity by oxidation-reduction in vitro. Proc. Natl. Acad. Sci. USA 88, 4328-4332.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 4328-4332
-
-
Toledano, M.B.1
Leonard, W.J.2
-
136
-
-
33644652602
-
Airing out an antioxidant role for the tumor suppressor p53
-
Tomko, R. J., Bansal, P. and Lazo, J. S. (2006). Airing out an antioxidant role for the tumor suppressor p53. Mol. Interv. 6, 23-25, 2.
-
(2006)
Mol. Interv
, vol.6
, pp. 23-25, 2
-
-
Tomko, R.J.1
Bansal, P.2
Lazo, J.S.3
-
137
-
-
80053904684
-
Mitochondrial complex III ROS regulate adipocyte differentiation
-
Tormos, K. V., Anso, E., Hamanaka, R. B., Eisenbart, J., Joseph, J., Kalyanaraman, B. and Chandel, N. S. (2011). Mitochondrial complex III ROS regulate adipocyte differentiation. Cell Metabol. 14, 537-544.
-
(2011)
Cell Metabol
, vol.14
, pp. 537-544
-
-
Tormos, K.V.1
Anso, E.2
Hamanaka, R.B.3
Eisenbart, J.4
Joseph, J.5
Kalyanaraman, B.6
Chandel, N.S.7
-
138
-
-
33846419112
-
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
-
T othova, Z., Kollipara, R., Huntly, B. J., Lee, B. H., Castrillon, D. H., Cullen, D. E., McDowell, E. P., Lazo-Kallanian, S., Williams, I. R., Sears, C. et al. (2007). FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell 128, 325-339.
-
(2007)
Cell
, vol.128
, pp. 325-339
-
-
T Othova, Z.1
Kollipara, R.2
Huntly, B.J.3
Lee, B.H.4
Castrillon, D.H.5
Cullen, D.E.6
McDowell, E.P.7
Lazo-Kallanian, S.8
Williams, I.R.9
Sears, C.10
-
139
-
-
70349469788
-
DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells
-
T rowbridge, J. J., Snow, J. W., Kim, J. and Orkin, S. H. (2009). DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells. Cell Stem Cell 5, 442-449.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 442-449
-
-
T Rowbridge, J.J.1
Snow, J.W.2
Kim, J.3
Orkin, S.H.4
-
140
-
-
43149111604
-
Functional interaction between FOXO3a and ATM regulates DNA damage response
-
T sai, W. B., Chung, Y. M., Takahashi, Y., Xu, Z., Hu, M. C., (2008). Functional interaction between FOXO3a and ATM regulates DNA damage response. Nat. Cell Biol. 10, 460-467.
-
(2008)
Nat. Cell Biol
, vol.10
, pp. 460-467
-
-
T Sai, W.B.1
Chung, Y.M.2
Takahashi, Y.3
Xu, Z.4
Hu, M.C.5
-
141
-
-
84874655208
-
Nrf2 regulates haematopoietic stem cell function
-
T sai, J. J., Dudakov, J. A., Takahashi, K., Shieh, J.-H., Velardi, E., Holland, A. M., Singer, N. V., West, M. L., Smith, O. M., Young, L. F. et al. (2013). Nrf2 regulates haematopoietic stem cell function. Nat. Cell Biol. 15, 309-316.
-
(2013)
Nat. Cell Biol
, vol.15
, pp. 309-316
-
-
T Sai, J.J.1
Dudakov, J.A.2
Takahashi, K.3
Shieh, J.-H.4
Velardi, E.5
Holland, A.M.6
Singer, N.V.7
West, M.L.8
Smith, O.M.9
Young, L.F.10
-
142
-
-
33744926266
-
Quantitative proteomics reveals posttranslational control as a regulatory factor in primary hematopoietic stem cells
-
U nwin, R. D., Smith, D. L., Blinco, D., Wilson, C. L., Miller, C. J., Evans, C. A., Jaworska, E., Baldwin, S. A., Barnes, K., Pierce, A., et al. (2006). Quantitative proteomics reveals posttranslational control as a regulatory factor in primary hematopoietic stem cells. Blood 107, 4687-4694.
-
(2006)
Blood
, vol.107
, pp. 4687-4694
-
-
U Nwin, R.D.1
Smith, D.L.2
Blinco, D.3
Wilson, C.L.4
Miller, C.J.5
Evans, C.A.6
Jaworska, E.7
Baldwin, S.A.8
Barnes, K.9
Pierce, A.10
-
143
-
-
84870290830
-
Redox regulation of stem/progenitor cells and bone marrow niche
-
U rao, N. and Ushio-Fukai, M. (2013). Redox regulation of stem/progenitor cells and bone marrow niche. Free Radic. Biol. Med. 54, 26-39.
-
(2013)
Free Radic. Biol. Med
, vol.54
, pp. 26-39
-
-
U Rao, N.1
Ushio-Fukai, M.2
-
144
-
-
0030613796
-
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria
-
V ander Heiden, M. G., Chandel, N. S., Williamson, E. K., Schumacker, P. T. and Thompson, C. B. (1997). Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell 91, 627-637.
-
(1997)
Cell
, vol.91
, pp. 627-637
-
-
V Ander Heiden, M.G.1
Chandel, N.S.2
Williamson, E.K.3
Schumacker, P.T.4
Thompson, C.B.5
-
145
-
-
3142742707
-
FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1)
-
Van der Horst, A., Tertoolen, L. G. J., de Vries-Smits, L. M. M., Frye, R. A., Medema, R. H. and Burgering, B. M. T. (2004). FOXO4 is acetylated upon peroxide stress and deacetylated by the longevity protein hSir2(SIRT1). J. Biol. Chem. 279, 28873-28879.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 28873-28879
-
-
Van Der Horst, A.1
Tertoolen, L.G.J.2
De Vries-Smits, L.M.M.3
Frye, R.A.4
Medema, R.H.5
Burgering, B.M.T.6
-
146
-
-
0035913903
-
HSIR2(SIRT1) functions as an NADdependent p53 deacetylase
-
Vaziri, H., Dessain, S. K., Ng Eaton, E., Imai, S.-I., Frye, R. A., Pandita, T. K., Guarente, L. and Weinberg, R. A. (2001). hSIR2(SIRT1) functions as an NADdependent p53 deacetylase. Cell 107, 149-159.
-
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng Eaton, E.3
Imai, S.-I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
Weinberg, R.8
-
147
-
-
34347329257
-
Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress
-
Velu, C. S., Niture, S. K., Doneanu, C. E., Pattabiraman, N. and Srivenugopal, K. S. (2007). Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress. Biochemistry 46, 7765-7780.
-
(2007)
Biochemistry
, vol.46
, pp. 7765-7780
-
-
Velu, C.S.1
Niture, S.K.2
Doneanu, C.E.3
Pattabiraman, N.4
Srivenugopal, K.S.5
-
148
-
-
0029906134
-
Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:Quinone oxidoreductase1 gene
-
Venugopal, R. and Jaiswal, A. K. (1996). Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene. Proc. Natl. Acad. Sci. USA 93, 14960-14965.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 14960-14965
-
-
Venugopal, R.1
Jaiswal, A.K.2
-
149
-
-
0027324056
-
Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding
-
Walker, L. J., Robson, C. N., Black, E., Gillespie, D. and Hickson, I. D. (1993). Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding. Mol. Cell. Biol. 13, 5370-5376.
-
(1993)
Mol. Cell. Biol
, vol.13
, pp. 5370-5376
-
-
Walker, L.J.1
Robson, C.N.2
Black, E.3
Gillespie, D.4
Hickson, I.D.5
-
150
-
-
34047146388
-
Suppressing phosphatidylcholine-specific phospholipase C and elevating ROS level, NADPH oxidase activity and Rb level induced neuronal differentiation in mesenchymal stem cells
-
Wang, N., Xie, K., Huo, S., Zhao, J., Zhang, S. and Miao, J. (2007). Suppressing phosphatidylcholine-specific phospholipase C and elevating ROS level, NADPH oxidase activity and Rb level induced neuronal differentiation in mesenchymal stem cells. J. Cell. Biochem. 100, 1548-1557.
-
(2007)
J. Cell. Biochem
, vol.100
, pp. 1548-1557
-
-
Wang, N.1
Xie, K.2
Huo, S.3
Zhao, J.4
Zhang, S.5
Miao, J.6
-
151
-
-
67749140110
-
Dependence of mouse embryonic stem cells on threonine catabolism
-
Wang, J., Alexander, P., Wu, L., Hammer, R., Cleaver, O. and McKnight, S. L. (2009). Dependence of mouse embryonic stem cells on threonine catabolism. Science 325, 435-439.
-
(2009)
Science
, vol.325
, pp. 435-439
-
-
Wang, J.1
Alexander, P.2
Wu, L.3
Hammer, R.4
Cleaver, O.5
McKnight, S.L.6
-
152
-
-
84908058792
-
Cell-statespecific metabolic dependency in hematopoiesis and leukemogenesis
-
Wang, Y.-H., Israelsen, W. J., Lee, D., Yu, V. W. C., Jeanson, N. T., Clish, C. B., Cantley, L. C., Vander Heiden, M. G. and Scadden, D. T. (2014). Cell-statespecific metabolic dependency in hematopoiesis and leukemogenesis. Cell 158, 1309-1323.
-
(2014)
Cell
, vol.158
, pp. 1309-1323
-
-
Wang, Y.-H.1
Israelsen, W.J.2
Lee, D.3
Yu, V.W.C.4
Jeanson, N.T.5
Clish, C.B.6
Cantley, L.C.7
Vander Heiden, M.G.8
Scadden, D.T.9
-
153
-
-
84858604270
-
Metabolic reprogramming: A cancer hallmark even warburg did not anticipate
-
Ward, P. S. and Thompson, C. B. (2012). Metabolic reprogramming: a cancer hallmark even warburg did not anticipate. Cancer Cell 21, 297-308.
-
(2012)
Cancer Cell
, vol.21
, pp. 297-308
-
-
Ward, P.S.1
Thompson, C.B.2
-
154
-
-
84876687303
-
Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment. Nat
-
Will, B., Vogler, T. O., Bartholdy, B., Garrett-Bakelman, F., Mayer, J., Barreyro, L., Pandolfi, A., Todorova, T. I., Okoye-Okafor, U. C., Stanley, R. F. et al. (2013). Satb1 regulates the self-renewal of hematopoietic stem cells by promoting quiescence and repressing differentiation commitment. Nat. Immunol. 14, 437-445.
-
(2013)
Immunol
, vol.14
, pp. 437-445
-
-
Will, B.1
Vogler, T.O.2
Bartholdy, B.3
Garrett-Bakelman, F.4
Mayer, J.5
Barreyro, L.6
Pandolfi, A.7
Todorova, T.I.8
Okoye-Okafor, U.C.9
Stanley, R.F.10
-
155
-
-
56549128268
-
Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
-
Wilson, A., Laurenti, E., Oser, G., van der Wath, R. C., Blanco-Bose, W., Jaworski, M., Offner, S., Dunant, C. F., Eshkind, L., Bockamp, E. et al. (2008). Hematopoietic stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair. Cell 135, 1118-1129.
-
(2008)
Cell
, vol.135
, pp. 1118-1129
-
-
Wilson, A.1
Laurenti, E.2
Oser, G.3
Van Der Wath, R.C.4
Blanco-Bose, W.5
Jaworski, M.6
Offner, S.7
Dunant, C.F.8
Eshkind, L.9
Bockamp, E.10
-
156
-
-
84890115755
-
Current methods to study reactive oxygen species–pros and cons. Preface. Biochim. Biophys
-
Winterbourn, C. (2014). Current methods to study reactive oxygen species–pros and cons. Preface. Biochim. Biophys. Acta 1840, 707.
-
(2014)
Acta
, vol.1840
, pp. 707
-
-
Winterbourn, C.1
-
157
-
-
65649128653
-
Embryonic stem cell differentiation into smooth muscle cells is mediated by Nox4-produced H2O2. A m
-
Xiao, Q., Luo, Z., Pepe, A. E., Margariti, A., Zeng, L. and Xu, Q. (2009). Embryonic stem cell differentiation into smooth muscle cells is mediated by Nox4-produced H2O2. A m. J. Physiol. Cell Physiol. 296, C711-C723.
-
(2009)
J. Physiol. Cell Physiol
, vol.296
, pp. C711-C723
-
-
Xiao, Q.1
Luo, Z.2
Pepe, A.E.3
Margariti, A.4
Zeng, L.5
Xu, Q.6
-
158
-
-
84862632865
-
Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors
-
X iao, M., Yang, H., Xu, W., Ma, S., Lin, H., Zhu, H., Liu, L., Liu, Y., Yang, C., Xu, Y. et al. (2012). Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors. Genes Dev. 26, 1326-1338.
-
(2012)
Genes Dev
, vol.26
, pp. 1326-1338
-
-
X Iao, M.1
Yang, H.2
Xu, W.3
Ma, S.4
Lin, H.5
Zhu, H.6
Liu, L.7
Liu, Y.8
Yang, C.9
Xu, Y.10
-
159
-
-
80052930073
-
Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells
-
Y ahata, T., Takanashi, T., Muguruma, Y., Ibrahim, A. A., Matsuzawa, H., Uno, T., Sheng, Y., Onizuka, M., Ito, M., Kato, S. et al. (2011). Accumulation of oxidative DNA damage restricts the self-renewal capacity of human hematopoietic stem cells. Blood 118, 2941-2950.
-
(2011)
Blood
, vol.118
, pp. 2941-2950
-
-
Y Ahata, T.1
Takanashi, T.2
Muguruma, Y.3
Ibrahim, A.A.4
Matsuzawa, H.5
Uno, T.6
Sheng, Y.7
Onizuka, M.8
Ito, M.9
Kato, S.10
-
160
-
-
54449092731
-
Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells
-
Y alcin, S., Zhang, X., Luciano, J. P., Mungamuri, S. K., Marinkovic, D., Vercherat, C., Sarkar, A., Grisotto, M., Taneja, R. and Ghaffari, S. (2008). Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells. J. Biol. Chem. 283, 25692-25705.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 25692-25705
-
-
Y Alcin, S.1
Zhang, X.2
Luciano, J.P.3
Mungamuri, S.K.4
Marinkovic, D.5
Vercherat, C.6
Sarkar, A.7
Grisotto, M.8
Taneja, R.9
Ghaffari, S.10
-
161
-
-
78650302424
-
ROS-mediated amplification of AKT/mTOR signalling pathway leads to myeloproliferative syndrome in Foxo3(-/-) mice
-
Y alcin, S., Marinkovic, D., Mungamuri, S. K., Zhang, X., Tong, W., Sellers, R. and Ghaffari, S. (2010). ROS-mediated amplification of AKT/mTOR signalling pathway leads to myeloproliferative syndrome in Foxo3(-/-) mice. EMBO J. 29, 4118-4131.
-
(2010)
EMBO J
, vol.29
, pp. 4118-4131
-
-
Y Alcin, S.1
Marinkovic, D.2
Mungamuri, S.K.3
Zhang, X.4
Tong, W.5
Sellers, R.6
Ghaffari, S.7
-
162
-
-
77952545479
-
etabolic oxidation regulates embryonic stemcell differentiation
-
Yanes, O., Clark, J., Wong, D. M., Patti, G. J., Sanchez-Ruiz, A., Benton, H. P., Trauger, S. A., Desponts, C., Ding, S. and Siuzdak, G. (2010). Metabolic oxidation regulates embryonic stemcell differentiation. Nat. Chem. Biol. 6, 411-417.
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 411-417
-
-
Yanes, O.1
Clark, J.2
Wong, D.M.3
Patti, G.J.4
SaNchez-Ruiz, A.5
Benton, H.P.6
Trauger, S.A.7
Desponts, C.8
Ding, S.9
Siuzdak, G.10
-
163
-
-
82555170271
-
Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation
-
Yang, W., Xia, Y., Ji, H., Zheng, Y., Liang, J., Huang, W., Gao, X., Aldape, K. and Lu, Z. (2011). Nuclear PKM2 regulates β-catenin transactivation upon EGFR activation. Nature 478, 118-122.
-
(2011)
Nature
, vol.478
, pp. 118-122
-
-
Yang, W.1
Xia, Y.2
Ji, H.3
Zheng, Y.4
Liang, J.5
Huang, W.6
Gao, X.7
Aldape, K.8
Lu, Z.9
-
164
-
-
84885172074
-
FoxO3 coordinates metabolic pathways to maintain redox balance in neural stem cells
-
Yeo, H., Lyssiotis, C. A., Zhang, Y., Ying, H., Asara, J. M., Cantley, L. C. and Paik, J.-H. (2013). FoxO3 coordinates metabolic pathways to maintain redox balance in neural stem cells. EMBO J. 32, 2531-2656.
-
(2013)
EMBO J
, vol.32
, pp. 2531-2656
-
-
Yeo, H.1
Lyssiotis, C.A.2
Zhang, Y.3
Ying, H.4
Asara, J.M.5
Cantley, L.C.6
Paik, J.-H.7
-
165
-
-
80052736325
-
Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway
-
Yoshida, S., Hong, S., Suzuki, T., Nada, S., Mannan, A. M., Wang, J., Okada, M., Guan, K.-L. and Inoki, K. (2011). Redox regulates mammalian target of rapamycin complex 1 (mTORC1) activity by modulating the TSC1/TSC2-Rheb GTPase pathway. J. Biol. Chem. 286, 32651-32660.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 32651-32660
-
-
Yoshida, S.1
Hong, S.2
Suzuki, T.3
Nada, S.4
Mannan, A.M.5
Wang, J.6
Okada, M.7
Guan, K.-L.8
Inoki, K.9
-
166
-
-
84865544952
-
Mitochondrial fission, fusion, and stress
-
Youle, R. J. and van der Bliek, A. M. (2012). Mitochondrial fission, fusion, and stress. Science 337, 1062-1065.
-
(2012)
Science
, vol.337
, pp. 1062-1065
-
-
Youle, R.J.1
Van Der Bliek, A.M.2
-
167
-
-
84872037830
-
Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation
-
Yu, W.-M., Liu, X., Shen, J., Jovanovic, O., Pohl, E. E., Gerson, S. L., Finkel, T., Broxmeyer, H. E. and Qu, C.-K. (2013). Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation. Cell Stem Cell 12, 62-74.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 62-74
-
-
Yu, W.-M.1
Liu, X.2
Shen, J.3
Jovanovic, O.4
Pohl, E.E.5
Gerson, S.L.6
Finkel, T.7
Broxmeyer, H.E.8
Qu, C.-K.9
-
168
-
-
77955862787
-
Redox regulation of sirtuin-1 by S-glutathiolation. Antioxid
-
Zee, R. S., Yoo, C. B., Pimentel, D. R., Perlman, D. H., Burgoyne, J. R., Hou, X., McComb, M. E., Costello, C. E., Cohen, R. A. and Bachschmid, M. M. (2010). Redox regulation of sirtuin-1 by S-glutathiolation. Antioxid. Redox Signal. 13, 1023-1032.
-
(2010)
Redox Signal
, vol.13
, pp. 1023-1032
-
-
Zee, R.S.1
Yoo, C.B.2
Pimentel, D.R.3
Perlman, D.H.4
Burgoyne, J.R.5
Hou, X.6
McComb, M.E.7
Costello, C.E.8
Cohen, R.A.9
Bachschmid, M.M.10
-
169
-
-
80052490840
-
OXO1 is an essential regulator of pluripotency in human embryonic stem cells
-
Zhang, X., Yalcin, S., Lee, D.-F., Yeh, T.-Y. J., Lee, S.-M., Su, J., Mungamuri, S. K., Rimmele P., Kennedy, M., Sellers, R. et al. (2011a). FOXO1 is an essential regulator of pluripotency in human embryonic stem cells. Nat. Cell Biol. 13, 1092-1099.
-
(2011)
Nat. Cell Biol.
, vol.3
, pp. 092-1099.
-
-
Zhang, X.1
Yalcin, S.2
Lee, D.-F.3
Yeh, T.-Y.J.4
Lee, S.-M.5
Su, J.6
Mungamuri, S.K.7
Rimmele, P.8
Kennedy, M.9
Sellers, R.10
-
170
-
-
83455235489
-
UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells
-
Zhang, J., Khvorostov, I., Hong, J. S., Oktay, Y., Vergnes, L., Nuebel, E., Wahjudi, P. N., Setoguchi, K., Wang, G., Do, A. et al. (2011b). UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells. EMBO J. 30, 4860-4873.
-
(2011)
EMBO J
, vol.30
, pp. 4860-4873
-
-
Zhang, J.1
Khvorostov, I.2
Hong, J.S.3
Oktay, Y.4
Vergnes, L.5
Nuebel, E.6
Wahjudi, P.N.7
Setoguchi, K.8
Wang, G.9
Do, A.10
-
171
-
-
79959918521
-
Regulation and function of FoxO transcription factors in normal and cancer stem cells: What have we learned
-
Zhang, X., Rielland, M., Yalcin, S. and Ghaffari, S. (2011c). Regulation and function of FoxO transcription factors in normal and cancer stem cells: what have we learned? Curr. Drug Targets 12, 1267-1283.
-
(2011)
Curr. Drug Targets
, vol.12
, pp. 1267-1283
-
-
Zhang, X.1
Rielland, M.2
Yalcin, S.3
Ghaffari, S.4
-
172
-
-
84868351585
-
Metabolic regulation in pluripotent stem cells during reprogramming and selfrenewal
-
Zhang, J., Nuebel, E., Daley, G. Q., Koehler, C. M. and Teitell, M. A. (2012). Metabolic regulation in pluripotent stem cells during reprogramming and selfrenewal. Cell Stem Cell 11, 589-595.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 589-595
-
-
Zhang, J.1
Nuebel, E.2
Daley, G.Q.3
Koehler, C.M.4
Teitell, M.A.5
-
173
-
-
84908029999
-
XO3-mTOR metabolic cooperation in the regulation of erythroid cell maturation and homeostasis.
-
Zhang, X., Camprecios, G., Rimmele P., Liang, R., Yalcin, S., Mungamuri, S. K., Barminko, J., D’Escamard, V., Baron, M. H., Brugnara, C. et al. (2014). FOXO3-mTOR metabolic cooperation in the regulation of erythroid cell maturation and homeostasis. Am. J. Hematol. 89, 954-963.
-
(2014)
J. Hematol.
, pp. 4-963
-
-
Zhang, X.1
Camprecios, G.2
Rimmele, P.3
Liang, R.4
Yalcin, S.5
Mungamuri, S.K.6
Barminko, J.7
D’escamard, V.8
Baron, M.H.9
Brugnara, C.10
-
174
-
-
84860531487
-
HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to- EpiSC/hESC transition
-
Zhou, W., Choi, M., Margineantu, D., Margaretha, L., Hesson, J., Cavanaugh, C., Blau, C. A., Horwitz, M. S., Hockenbery, D., Ware, C. et al. (2012). HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC-to- EpiSC/hESC transition. EMBO J. 31, 2103-2116.
-
(2012)
EMBO J
, vol.31
, pp. 2103-2116
-
-
Zhou, W.1
Choi, M.2
Margineantu, D.3
Margaretha, L.4
Hesson, J.5
Cavanaugh, C.6
Blau, C.A.7
Horwitz, M.S.8
Hockenbery, D.9
Ware, C.10
-
175
-
-
78649647814
-
Reprogramming of human primary somatic cells by OCT4 and chemical compounds
-
Z hu, S., Li, W., Zhou, H., Wei, W., Ambasudhan, R., Lin, T., Kim, J., Zhang, K. and Ding, S. (2010). Reprogramming of human primary somatic cells by OCT4 and chemical compounds. Cell Stem Cell 7, 651-655.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 651-655
-
-
Z Hu, S.1
Li, W.2
Zhou, H.3
Wei, W.4
Ambasudhan, R.5
Lin, T.6
Kim, J.7
Zhang, K.8
Ding, S.9
-
176
-
-
33847377224
-
Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain
-
Zou, G.-M., Luo, M.-H., Reed, A., Kelley, M. R. and Yoder, M. C. (2007). Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain. Blood 109, 1917-1922.
-
(2007)
Blood
, vol.109
, pp. 1917-1922
-
-
Zou, G.-M.1
Luo, M.-H.2
Reed, A.3
Kelley, M.R.4
Yoder, M.C.5
|