Glucose metabolism impacts the spatiotemporal onset and magnitude of HSC induction in vivo

Blood

Volumn 121, Issue 13, 2013, Pages 2483-2493

  Harris, James M ^a   Esain, Virginie ^a   Frechette, Gregory M ^a   Harris, Lauren J ^a   Cox, Andrew G ^a   Cortes, Mauricio ^a   Garnaas, Maija K ^a   Carroll, Kelli J ^a   Cutting, Claire C ^a   Khan, Tahsin ^b   Elks, Philip M ^c   Renshaw, Stephen A ^c   Dickinson, Bryan C ^d   Chang, Christopher J ^d   Murphy, Michael P ^e   Paw, Barry H ^a   Vander Heiden, Matthew G ^a,b   Goessling, Wolfram ^a,f   North, Trista E ^a,f  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c MEDICAL RESEARCH COUNCIL   (United Kingdom)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR RUNX1; HYPOXIA INDUCIBLE FACTOR 1ALPHA;

ANIMAL CELL; AORTA; ARTICLE; CELL METABOLISM; CELL STIMULATION; CONTROLLED STUDY; EMBRYO; EPISTASIS; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; GLYCOLYSIS; GONAD; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; IN VIVO STUDY; MESONEPHROS; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SPATIOTEMPORAL ANALYSIS; STEM CELL EXPANSION; ZEBRA FISH; ANIMAL; ANIMAL EMBRYO; CARBOHYDRATE METABOLISM; CELL PROLIFERATION; CYTOLOGY; DRUG EFFECT; EMBRYO INDUCTION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; PRENATAL DEVELOPMENT; TIME; TRANSGENIC ANIMAL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CARBOHYDRATE METABOLISM; CELL PROLIFERATION; EMBRYO, NONMAMMALIAN; EMBRYONIC INDUCTION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUCOSE; GLYCOLYSIS; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; OXIDATIVE PHOSPHORYLATION; TIME FACTORS; ZEBRAFISH;

MLCS; MLOWN;

EID: 84878414798     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2012-12-471201     Document Type: Article

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