-
1
-
-
8844247034
-
Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes
-
Alcendor RR, Kirshenbaum LA, Imai S, Vatner SF, and Sa-doshima J. Silent information regulator 2alpha, a longevity factor and class III histone deacetylase, is an essential endogenous apoptosis inhibitor in cardiac myocytes. Circ Res 95: 971-980, 2004.
-
(2004)
Circ Res
, vol.95
, pp. 971-980
-
-
Alcendor, R.R.1
Kirshenbaum, L.A.2
Imai, S.3
Vatner, S.F.4
Sa-Doshima, J.5
-
2
-
-
77957655795
-
Human sirt-1: Molecular modeling and structure-function relationships of an unordered protein
-
Autiero I, Costantini S, and Colonna G. Human sirt-1: Molecular modeling and structure-function relationships of an unordered protein. PLoS ONE 4: e7350, 2008.
-
(2008)
PLoS ONE
, vol.4
-
-
Autiero, I.1
Costantini, S.2
Colonna, G.3
-
3
-
-
0031458341
-
Modification of aldose reductase by S-nitrosoglutathione
-
Chandra A, Srivastava S, Petrash JM, Bhatnagar A, and Srivastava SK. Modification of aldose reductase by S-nitrosoglutathione. Biochemistry 36: 15801-15809, 1997.
-
(1997)
Biochemistry
, vol.36
, pp. 15801-15809
-
-
Chandra, A.1
Srivastava, S.2
Petrash, J.M.3
Bhatnagar, A.4
Srivastava, S.K.5
-
4
-
-
49249100288
-
Vasoprotective effects of resver-atrol and SIRT1: Attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations
-
Csiszar A, Labinskyy N, Podlutsky A, Kaminski PM, Wolin MS, Zhang C, Mukhopadhyay P, Pacher P, Hu F, de CR, Ballabh P, and Ungvari Z. Vasoprotective effects of resver-atrol and SIRT1: Attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations. Am J Physiol Heart Circ Physiol 294: H2721-H2735, 2008.
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.294
-
-
Csiszar, A.1
Labinskyy, N.2
Podlutsky, A.3
Kaminski, P.M.4
Wolin, M.S.5
Zhang, C.6
Mukhopadhyay, P.7
Pacher, P.8
Hu, F.9
De, C.R.10
Ballabh, P.11
Ungvari, Z.12
-
5
-
-
33749365317
-
Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: Role of NF-kappaB inhibition
-
Csiszar A, Smith K, Labinskyy N, Orosz Z, Rivera A, and Ungvari Z. Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: Role of NF-kappaB inhibition. Am J Physiol Heart Circ Physiol 291: H1694-H1699, 2006.
-
(2006)
Am J Physiol Heart Circ Physiol
, vol.291
-
-
Csiszar, A.1
Smith, K.2
Labinskyy, N.3
Orosz, Z.4
Rivera, A.5
Ungvari, Z.6
-
6
-
-
0043244921
-
Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state
-
Fulco M, Schiltz RL, Iezzi S, King MT, Zhao P, Kashiwaya Y, Hoffman E, Veech RL, and Sartorelli V. Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state. Mol Cell 12: 51-62, 2003.
-
(2003)
Mol Cell
, vol.12
, pp. 51-62
-
-
Fulco, M.1
Schiltz, R.L.2
Iezzi, S.3
King, M.T.4
Zhao, P.5
Kashiwaya, Y.6
Hoffman, E.7
Veech, R.L.8
Sartorelli, V.9
-
7
-
-
18844410338
-
S-nitrosation versus S-glutathionylation of protein sulfhydryl groups by S-nitrosoglutathione
-
Giustarini D, Milzani A, Aldini G, Carini M, Rossi R, and le-Donne I. S-nitrosation versus S-glutathionylation of protein sulfhydryl groups by S-nitrosoglutathione. Antioxid Redox Signal 7: 930-939, 2005.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 930-939
-
-
Giustarini, D.1
Milzani, A.2
Aldini, G.3
Carini, M.4
Rossi, R.5
Le-Donne, I.6
-
8
-
-
0000071405
-
Some observations concerning the S-nitroso and S-phenylsulphonyl derivatives of L-cysteine and glutathione
-
Hart TW. Some observations concerning the S-nitroso and S-phenylsulphonyl derivatives of L-cysteine and glutathione. Tetrahedron Lett 26: 2013-2016, 1985.
-
(1985)
Tetrahedron Lett
, vol.26
, pp. 2013-2016
-
-
Hart, T.W.1
-
9
-
-
0032983979
-
Nitric oxide inhibits c-Jun DNA binding by specifically targeted S-glutathionylation
-
Klatt P, Molina EP, and Lamas S. Nitric oxide inhibits c-Jun DNA binding by specifically targeted S-glutathionylation. J Biol Chem 274: 15857-15864, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 15857-15864
-
-
Klatt, P.1
Molina, E.P.2
Lamas, S.3
-
10
-
-
0034662178
-
Novel application of S-nitrosoglutathione-Sepharose to identify proteins that are potential targets for S-nitrosoglutathione-induced mixed-disulphide formation
-
Klatt P, Pineda ME, Perez-Sala D, and Lamas S. Novel application of S-nitrosoglutathione-Sepharose to identify proteins that are potential targets for S-nitrosoglutathione-induced mixed-disulphide formation. Biochem J 349: 567-578, 2000.
-
(2000)
Biochem J
, vol.349
, pp. 567-578
-
-
Klatt, P.1
Pineda, M.E.2
Perez-Sala, D.3
Lamas, S.4
-
11
-
-
0037093346
-
Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence
-
Langley E, Pearson M, Faretta M, Bauer UM, Frye RA, Minucci S, Pelicci PG, and Kouzarides T. Human SIR2 deacetylates p53 and antagonizes PML/p53-induced cellular senescence. EMBO J 21: 2383-2396, 2002.
-
(2002)
EMBO J
, vol.21
, pp. 2383-2396
-
-
Langley, E.1
Pearson, M.2
Faretta, M.3
Bauer, U.M.4
Frye, R.A.5
Minucci, S.6
Pelicci, P.G.7
Kouzarides, T.8
-
12
-
-
0037167653
-
Red wine polyphenols enhance endothelial nitric oxide synthase expression and subsequent nitric oxide release from endothelial cells
-
Leikert JF, Rathel TR, Wohlfart P, Cheynier V, Vollmar AM, and Dirsch VM. Red wine polyphenols enhance endothelial nitric oxide synthase expression and subsequent nitric oxide release from endothelial cells. Circulation 106: 1614-1617, 2002.
-
(2002)
Circulation
, vol.106
, pp. 1614-1617
-
-
Leikert, J.F.1
Rathel, T.R.2
Wohlfart, P.3
Cheynier, V.4
Vollmar, A.M.5
Dirsch, V.M.6
-
13
-
-
0347128279
-
Calorie restriction extends yeast life span by lowering the level of NADH
-
Lin SJ, Ford E, Haigis M, Liszt G, and Guarente L. Calorie restriction extends yeast life span by lowering the level of NADH. Genes Dev 18: 12-16, 2004.
-
(2004)
Genes Dev
, vol.18
, pp. 12-16
-
-
Lin, S.J.1
Ford, E.2
Haigis, M.3
Liszt, G.4
Guarente, L.5
-
14
-
-
0031931823
-
S-Transni-trosation reactions are involved in the metabolic fate and biological actions of nitric oxide
-
Liu Z, Rudd MA, Freedman JE, and Loscalzo J. S-Transni-trosation reactions are involved in the metabolic fate and biological actions of nitric oxide. J Pharmacol Exp Ther 284: 526-534, 1998.
-
(1998)
J Pharmacol Exp Ther
, vol.284
, pp. 526-534
-
-
Liu, Z.1
Rudd, M.A.2
Freedman, J.E.3
Loscalzo, J.4
-
15
-
-
36749087548
-
Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes
-
Milne JC, Lambert PD, Schenk S, Carney DP, Smith JJ, Gagne DJ, Jin L, Boss O, Perni RB, Vu CB, Bemis JE, Xie R, Disch JS, Ng PY, Nunes JJ, Lynch AV, Yang H, Galonek H, Israelian K, Choy W, Iffland A, Lavu S, Medvedik O, Sinclair DA, Olefsky JM, Jirousek MR, Elliott PJ, and Westphal CH. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature 450: 712-716, 2007.
-
(2007)
Nature
, vol.450
, pp. 712-716
-
-
Milne, J.C.1
Lambert, P.D.2
Schenk, S.3
Carney, D.P.4
Smith, J.J.5
Gagne, D.J.6
Jin, L.7
Boss, O.8
Perni, R.B.9
Vu, C.B.10
Bemis, J.E.11
Xie, R.12
Disch, J.S.13
Ng, P.Y.14
Nunes, J.J.15
Lynch, A.V.16
Yang, H.17
Galonek, H.18
Israelian, K.19
Choy, W.20
Iffland, A.21
Lavu, S.22
Medvedik, O.23
Sinclair, D.A.24
Olefsky, J.M.25
Jirousek, M.R.26
Elliott, P.J.27
Westphal, C.H.28
more..
-
16
-
-
0035917536
-
Crystal structure of a SIR2 homolog-NAD complex
-
Min J, Landry J, Sternglanz R, and Xu RM. Crystal structure of a SIR2 homolog-NAD complex. Cell 105: 269-279, 2001.
-
(2001)
Cell
, vol.105
, pp. 269-279
-
-
Min, J.1
Landry, J.2
Sternglanz, R.3
Xu, R.M.4
-
17
-
-
0033515479
-
Nitric oxide-induced S-glutathionylation and inactivation of glyc-eraldehyde-3-phosphate dehydrogenase
-
Mohr S, Hallak H, de BA, Lapetina EG, and Brune B. Nitric oxide-induced S-glutathionylation and inactivation of glyc-eraldehyde-3-phosphate dehydrogenase. J Biol Chem 274: 9427-9430, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 9427-9430
-
-
Mohr, S.1
Hallak, H.2
De Ba Lapetina, E.G.3
Brune, B.4
-
18
-
-
29144501185
-
Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1
-
Napper AD, Hixon J, McDonagh T, Keavey K, Pons JF, Barker J, Yau WT, Amouzegh P, Flegg A, Hamelin E, Thomas RJ, Kates M, Jones S, Navia MA, Saunders JO, DiStefano PS, Curtis R. Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1. J Med Chem 48: 8045-8054, 2005.
-
(2005)
J Med Chem
, vol.48
, pp. 8045-8054
-
-
Napper, A.D.1
Hixon, J.2
McDonagh, T.3
Keavey, K.4
Pons, J.F.5
Barker, J.6
Yau, W.T.7
Amouzegh, P.8
Flegg, A.9
Hamelin, E.10
Thomas, R.J.11
Kates, M.12
Jones, S.13
Navia, M.A.14
Saunders, J.O.15
Distefano, P.S.16
Curtis, R.17
-
19
-
-
0033550050
-
Inhibition of cathepsin K by nitric oxide donors: Evidence for the formation of mixed disulfides and a sulfenic acid
-
Percival MD, Ouellet M, Campagnolo C, Claveau D, and Li C. Inhibition of cathepsin K by nitric oxide donors: Evidence for the formation of mixed disulfides and a sulfenic acid. Biochemistry 38: 13574-13583, 1999.
-
(1999)
Biochemistry
, vol.38
, pp. 13574-13583
-
-
Percival, M.D.1
Ouellet, M.2
Campagnolo, C.3
Claveau, D.4
Li, C.5
-
20
-
-
47849088748
-
Emerging roles of SIRT1 in vascular endothelial homeostasis
-
Potente M and Dimmeler S. Emerging roles of SIRT1 in vascular endothelial homeostasis. Cell Cycle 7: 2117-2122, 2008.
-
(2008)
Cell Cycle
, vol.7
, pp. 2117-2122
-
-
Potente, M.1
Dimmeler, S.2
-
21
-
-
42349085704
-
Sirt1 contributes critically to the redox-dependent fate of neural progenitors
-
Prozorovski T, Schulze-Topphoff U, Glumm R, Baumgart J, Schroter F, Ninnemann O, Siegert E, Bendix I, Brustle O, Nitsch R, Zipp F, and Aktas O. Sirt1 contributes critically to the redox-dependent fate of neural progenitors. Nat Cell Biol 10: 385-394, 2008.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 385-394
-
-
Prozorovski, T.1
Schulze-Topphoff, U.2
Glumm, R.3
Baumgart, J.4
Schroter, F.5
Ninnemann, O.6
Siegert, E.7
Bendix, I.8
Brustle, O.9
Nitsch, R.10
Zipp, F.11
Aktas, O.12
-
22
-
-
14544282413
-
Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1
-
Rodgers JT, Lerin C, Haas W, Gygi SP, Spiegelman BM, and Puigserver P. Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1. Nature 434: 113-118, 2005.
-
(2005)
Nature
, vol.434
, pp. 113-118
-
-
Rodgers, J.T.1
Lerin, C.2
Haas, W.3
Gygi, S.P.4
Spiegelman, B.M.5
Puigserver, P.6
-
23
-
-
58149202185
-
Phosphorylation regulates SIRT1 function
-
Sasaki T, Maier B, Koclega KD, Chruszcz M, Gluba W, Stukenberg PT, Minor W, and Scrable H. Phosphorylation regulates SIRT1 function. PLoS ONE 3: e4020, 2008.
-
(2008)
PLoS ONE
, vol.3
-
-
Sasaki, T.1
Maier, B.2
Koclega, K.D.3
Chruszcz, M.4
Gluba, W.5
Stukenberg, P.T.6
Minor, W.7
Scrable, H.8
-
24
-
-
4344677972
-
Determining cysteine oxidation status using differential alkylation
-
Schilling B, Yoo CB, Collins CJ, and Gibson BW. Determining cysteine oxidation status using differential alkylation. Int J Mass Spectrom 236: 117-127, 2004.
-
(2004)
Int J Mass Spectrom
, vol.236
, pp. 117-127
-
-
Schilling, B.1
Yoo, C.B.2
Collins, C.J.3
Gibson, B.W.4
-
25
-
-
14044257843
-
Glutaredoxin: Role in reversible protein S-glutathionylation and regulation of re-dox signal transduction and protein translocation
-
Shelton MD, Chock PB, and Mieyal JJ. Glutaredoxin: Role in reversible protein S-glutathionylation and regulation of re-dox signal transduction and protein translocation. Antioxid Redox Signal 7: 348-366, 2005.
-
(2005)
Antioxid Redox Signal
, vol.7
, pp. 348-366
-
-
Shelton, M.D.1
Chock, P.B.2
Mieyal, J.J.3
-
26
-
-
0035913903
-
And Weinberg RA. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase
-
Vaziri H, Dessain SK, Ng EE, Imai SI, Frye RA, Pandita TK, Guarente L, and Weinberg RA. hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell 107: 149-159, 2001.
-
(2001)
Cell
, vol.107
, pp. 149-159
-
-
Vaziri, H.1
Dessain, S.K.2
Ng, E.E.3
Imai, S.I.4
Frye, R.A.5
Pandita, T.K.6
Guarente, L.7
-
27
-
-
0037167677
-
Resveratrol, a polyphenolic phyto-alexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase
-
Wallerath T, Deckert G, Ternes T, Anderson H, Li H, Witte K, and Forstermann U. Resveratrol, a polyphenolic phyto-alexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase. Circulation 106: 1652-1658, 2002.
-
(2002)
Circulation
, vol.106
, pp. 1652-1658
-
-
Wallerath, T.1
Deckert, G.2
Ternes, T.3
Anderson, H.4
Li, H.5
Witte, K.6
Forstermann, U.7
-
28
-
-
33845600791
-
Protein glutathiolation by nitric oxide: An intracellular mechanism regulating redox protein modification
-
West MB, Hill BG, Xuan YT, and Bhatnagar A. Protein glutathiolation by nitric oxide: An intracellular mechanism regulating redox protein modification. FASEB J 20: 1715-1717, 2006.
-
(2006)
FASEB J
, vol.20
, pp. 1715-1717
-
-
West, M.B.1
Hill, B.G.2
Xuan, Y.T.3
Bhatnagar, A.4
-
29
-
-
35748962613
-
SIRT1 sumoylation regulates its dea-cetylase activity and cellular response to genotoxic stress
-
Yang Y, Fu W, Chen J, Olashaw N, Zhang X, Nicosia SV, Bhalla K, and Bai W. SIRT1 sumoylation regulates its dea-cetylase activity and cellular response to genotoxic stress. Nat Cell Biol 9: 1253-1262, 2007.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 1253-1262
-
-
Yang, Y.1
Fu, W.2
Chen, J.3
Olashaw, N.4
Zhang, X.5
Nicosia, S.V.6
Bhalla, K.7
Bai, W.8
-
30
-
-
0033597924
-
Mass spectrometric analysis of nitric oxide-modified caspase-3
-
Zech B, Wilm M, van ER, and Brune B. Mass spectrometric analysis of nitric oxide-modified caspase-3. J Biol Chem 274: 20931-20936, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 20931-20936
-
-
Zech, B.1
Wilm, M.2
Van, E.R.3
Brune, B.4
|