The histone methyltransferase activity of MLL1 is dispensable for hematopoiesis and leukemogenesis

Cell Reports

Volumn 7, Issue 4, 2014, Pages 1239-1247

  Mishra, Bibhu P ^a   Zaffuto, Kristin M ^a   Artinger, Erika L ^a   Org, Tonis ^b   Mikkola, Hanna K A ^b   Cheng, Chao ^a   Djabali, Malek ^c   Ernst, Patricia ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITÉ PAUL SABATIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; HISTONE H3; HISTONE METHYLTRANSFERASE; HYBRID PROTEIN; LYSINE 4; ONCOPROTEIN; POLYCOMB GROUP PROTEIN; SIRTUIN 1; UNCLASSIFIED DRUG; HISTONE ACETYLTRANSFERASE; HISTONE LYSINE METHYLTRANSFERASE; MIXED LINEAGE LEUKEMIA PROTEIN; MLL PROTEIN, MOUSE; MOF PROTEIN, MOUSE; SIRT1 PROTEIN, MOUSE; TRANSCRIPTION FACTOR; HISTONE METHYLTRANSFERASE MLL1; MLL AF9 FUSION ONCOPROTEIN; TRANSCRIPTION FACTOR EZH2;

ACETYLATION; ARTICLE; EMBRYO; ENZYME ACTIVITY; GENE ACTIVATION; GENE CONTROL; GENE DELETION; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; LEUKEMOGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FUNCTION; ANIMAL; CYTOLOGY; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE; PHYSIOLOGY; ANIMAL CELL; CONTROLLED STUDY; DEACETYLATION; GENE FUNCTION; HISTONE ACETYLATION; HISTONE METHYLATION; INTRINSIC ACTIVITY; MLL1 GENE; PROTEIN DEPLETION; PROTEIN PROTEIN INTERACTION; TRANSCRIPTION REGULATION;

ANIMALS; GENE EXPRESSION REGULATION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HISTONE ACETYLTRANSFERASES; HISTONE-LYSINE N-METHYLTRANSFERASE; MICE; MYELOID-LYMPHOID LEUKEMIA PROTEIN; SIRTUIN 1; TRANSCRIPTION FACTORS;

EID: 84901281295     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2014.04.015     Document Type: Article

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