-
1
-
-
0034490852
-
Chemoprotection against cancer by induction of phase 2 enzymes
-
P. Talalay Chemoprotection against cancer by induction of phase 2 enzymes Biofactors 12 2000 5 11
-
(2000)
Biofactors
, vol.12
, pp. 5-11
-
-
Talalay, P.1
-
2
-
-
0035965945
-
Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention
-
J.D. Hayes, and M. McMahon Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention Cancer Lett. 174 2001 103 113
-
(2001)
Cancer Lett.
, vol.174
, pp. 103-113
-
-
Hayes, J.D.1
McMahon, M.2
-
3
-
-
0025948113
-
The antioxidant responsive element; Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity
-
T.H. Rushmore The antioxidant responsive element; activation by oxidative stress and identification of the DNA consensus sequence required for functional activity J. Biol. Chem. 266 1991 11632 11639
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 11632-11639
-
-
Rushmore, T.H.1
-
4
-
-
0029906134
-
Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene
-
R. Venugopal Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene Proc. Natl. Acad. Sci. U. S. A. 93 1996 14960 14965
-
(1996)
Proc. Natl. Acad. Sci. U. S. A.
, vol.93
, pp. 14960-14965
-
-
Venugopal, R.1
-
5
-
-
0031577292
-
An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements
-
K. Itoh An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements Biochem. Biophys. Res. Commun. 236 1997 313 322
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.236
, pp. 313-322
-
-
Itoh, K.1
-
6
-
-
0037055265
-
Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors
-
H. Motohashi Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors Gene 294 2002 1 12
-
(2002)
Gene
, vol.294
, pp. 1-12
-
-
Motohashi, H.1
-
7
-
-
0037160092
-
Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression
-
H. Sasaki Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression J. Biol. Chem. 277 2002 44765 44771
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44765-44771
-
-
Sasaki, H.1
-
8
-
-
0141534255
-
Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein 1 in mouse embryo fibroblasts
-
A. Hayashi Transcription factor Nrf2 is required for the constitutive and inducible expression of multidrug resistance-associated protein 1 in mouse embryo fibroblasts Biochem. Biophys. Res. Commun. 310 2003 824 829
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.310
, pp. 824-829
-
-
Hayashi, A.1
-
9
-
-
13044304201
-
Nrf2 is essential for protection against acute pulmonary injury in mice
-
K. Chan, and Y.W. Kan Nrf2 is essential for protection against acute pulmonary injury in mice Proc. Natl. Acad. Sci. U. S. A. 96 1999 12731 12736
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, pp. 12731-12736
-
-
Chan, K.1
Kan, Y.W.2
-
10
-
-
0035153227
-
High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes
-
A. Enomoto High sensitivity of Nrf2 knockout mice to acetaminophen hepatotoxicity associated with decreased expression of ARE-regulated drug metabolizing enzymes and antioxidant genes Toxicol. Sci. 59 2001 169 177
-
(2001)
Toxicol. Sci.
, vol.59
, pp. 169-177
-
-
Enomoto, A.1
-
11
-
-
2342613543
-
Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 mice
-
C.E. Goldring Activation of hepatic Nrf2 in vivo by acetaminophen in CD-1 mice Hepatology 39 2004 1267 1276
-
(2004)
Hepatology
, vol.39
, pp. 1267-1276
-
-
Goldring, C.E.1
-
12
-
-
0035875447
-
Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust
-
Y. Aoki Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust Toxicol. Appl. Pharmacol. 173 2001 154 160
-
(2001)
Toxicol. Appl. Pharmacol.
, vol.173
, pp. 154-160
-
-
Aoki, Y.1
-
13
-
-
0035853157
-
Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice
-
M. Ramos-Gomez Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice Proc. Natl. Acad. Sci. U. S. A. 98 2001 3410 3415
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 3410-3415
-
-
Ramos-Gomez, M.1
-
14
-
-
0242329881
-
Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation
-
N. Wakabayashi Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation Nat. Genet. 35 2003 238 245
-
(2003)
Nat. Genet.
, vol.35
, pp. 238-245
-
-
Wakabayashi, N.1
-
15
-
-
0035313445
-
Reduced oxidative-stress response in red blood cells from p45NFE2-deficient mice
-
J.Y. Chan Reduced oxidative-stress response in red blood cells from p45NFE2-deficient mice Blood 97 2001 2151 2158
-
(2001)
Blood
, vol.97
, pp. 2151-2158
-
-
Chan, J.Y.1
-
16
-
-
0039726828
-
The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents
-
M. Kwong The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents J. Biol. Chem. 274 1999 37491 37498
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 37491-37498
-
-
Kwong, M.1
-
17
-
-
0347481377
-
Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress
-
L. Leung Deficiency of the Nrf1 and Nrf2 transcription factors results in early embryonic lethality and severe oxidative stress J. Biol. Chem. 278 2003 48021 48029
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 48021-48029
-
-
Leung, L.1
-
18
-
-
3042794972
-
Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes
-
A. Kobayashi Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes Methods Enzymol. 378 2004 273 286
-
(2004)
Methods Enzymol.
, vol.378
, pp. 273-286
-
-
Kobayashi, A.1
-
19
-
-
1842453034
-
Complexity of CNC transcription factors as revealed by gene targeting of the nrf3 locus
-
A. Derjuga Complexity of CNC transcription factors as revealed by gene targeting of the nrf3 locus Mol. Cell. Biol. 24 2004 3286 3294
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 3286-3294
-
-
Derjuga, A.1
-
20
-
-
0033956744
-
The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin
-
J.D. Hayes The Nrf2 transcription factor contributes both to the basal expression of glutathione S-transferases in mouse liver and to their induction by the chemopreventive synthetic antioxidants, butylated hydroxyanisole and ethoxyquin Biochem. Soc. Trans. 28 2000 33 41
-
(2000)
Biochem. Soc. Trans.
, vol.28
, pp. 33-41
-
-
Hayes, J.D.1
-
21
-
-
0037188518
-
Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobactor pylori and prevents benzo[a]pyrene-induced stomach tumors
-
J.W. Fahey Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobactor pylori and prevents benzo[a]pyrene-induced stomach tumors Proc. Natl. Acad. Sci. U. S. A. 99 2002 7610 7615
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 7610-7615
-
-
Fahey, J.W.1
-
22
-
-
0034717329
-
Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
-
T. Ishii Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages J. Biol. Chem. 275 2000 16023 16029
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16023-16029
-
-
Ishii, T.1
-
23
-
-
0036006792
-
Linkage analysis of susceptibility to hyperoxia. Nrf2 is a candidate gene
-
H-Y. Cho Linkage analysis of susceptibility to hyperoxia. Nrf2 is a candidate gene Am. J. Respir. Cell Mol. Biol. 26 2002 42 51
-
(2002)
Am. J. Respir. Cell Mol. Biol.
, vol.26
, pp. 42-51
-
-
Cho, H.-Y.1
-
24
-
-
0036007313
-
Role of NRF2 in protection against hyperoxic lung injury in mice
-
H-Y. Cho Role of NRF2 in protection against hyperoxic lung injury in mice Am. J. Respir. Cell Mol. Biol. 26 2002 175 182
-
(2002)
Am. J. Respir. Cell Mol. Biol.
, vol.26
, pp. 175-182
-
-
Cho, H.-Y.1
-
25
-
-
0037448015
-
EPR imaging of reducing activity in Nrf2 transcription factor-deficient mice
-
A. Hirayama EPR imaging of reducing activity in Nrf2 transcription factor-deficient mice Free Radic. Biol. Med. 34 2003 1236 1242
-
(2003)
Free Radic. Biol. Med.
, vol.34
, pp. 1236-1242
-
-
Hirayama, A.1
-
26
-
-
0034785941
-
Nrf2-deficient female mice develop lupus-like autoimmune nephritis
-
K. Yoh Nrf2-deficient female mice develop lupus-like autoimmune nephritis Kidney Int. 60 2001 1343 1353
-
(2001)
Kidney Int.
, vol.60
, pp. 1343-1353
-
-
Yoh, K.1
-
27
-
-
0034752461
-
Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription
-
Y. Katoh Two domains of Nrf2 cooperatively bind CBP, a CREB binding protein, and synergistically activate transcription Genes Cells 6 2001 857 868
-
(2001)
Genes Cells
, vol.6
, pp. 857-868
-
-
Katoh, Y.1
-
28
-
-
0033637756
-
Positive of negative MARE-dependent transcriptional regulation is determined by the abundance of small Maf proteins
-
H. Motohashi Positive of negative MARE-dependent transcriptional regulation is determined by the abundance of small Maf proteins Cell 103 2000 865 875
-
(2000)
Cell
, vol.103
, pp. 865-875
-
-
Motohashi, H.1
-
29
-
-
1942520367
-
Nrf2 signaling in coordinated activation of antioxidant gene expression
-
A.K. Jaiswal Nrf2 signaling in coordinated activation of antioxidant gene expression Free Radic. Biol. Med. 36 2004 1199 1207
-
(2004)
Free Radic. Biol. Med.
, vol.36
, pp. 1199-1207
-
-
Jaiswal, A.K.1
-
30
-
-
2342511435
-
Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway
-
H. Motohashi Small Maf proteins serve as transcriptional cofactors for keratinocyte differentiation in the Keap1-Nrf2 regulatory pathway Proc. Natl. Acad. Sci. U. S. A. 101 2004 6379 6384
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 6379-6384
-
-
Motohashi, H.1
-
31
-
-
0032953192
-
Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
-
K. Itoh Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain Genes Dev. 13 1999 76 86
-
(1999)
Genes Dev.
, vol.13
, pp. 76-86
-
-
Itoh, K.1
-
32
-
-
0036668466
-
Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system
-
M. Kobayashi Identification of the interactive interface and phylogenic conservation of the Nrf2-Keap1 system Genes Cells 7 2002 807 820
-
(2002)
Genes Cells
, vol.7
, pp. 807-820
-
-
Kobayashi, M.1
-
33
-
-
3843104763
-
Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron
-
M. McMahon Redox-regulated turnover of Nrf2 is determined by at least two separate protein domains, the redox-sensitive Neh2 degron and the redox-insensitive Neh6 degron J. Biol. Chem. 279 2004 31556 31567
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 31556-31567
-
-
McMahon, M.1
-
34
-
-
0042626242
-
Skn-1 links C. elegans mesodermal specification to a conserved oxidative stress response
-
J. Hyung, and T.K. Blackwell Skn-1 links C. elegans mesodermal specification to a conserved oxidative stress response Genes Dev. 17 2003 1882 1893
-
(2003)
Genes Dev.
, vol.17
, pp. 1882-1893
-
-
Hyung, J.1
Blackwell, T.K.2
-
35
-
-
0037462651
-
Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium
-
D. Stewart Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium J. Biol. Chem. 278 2003 2396 2402
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 2396-2402
-
-
Stewart, D.1
-
36
-
-
0013282861
-
Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome
-
T. Nguyen Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome J. Biol. Chem. 287 2003 4536 4541
-
(2003)
J. Biol. Chem.
, vol.287
, pp. 4536-4541
-
-
Nguyen, T.1
-
37
-
-
0037821802
-
Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression
-
M. McMahon Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression J. Biol. Chem. 278 2003 21592 21600
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 21592-21600
-
-
McMahon, M.1
-
38
-
-
12444257799
-
Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles
-
K. Itoh Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles Genes Cells 8 2003 379 391
-
(2003)
Genes Cells
, vol.8
, pp. 379-391
-
-
Itoh, K.1
-
39
-
-
0037015035
-
Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants
-
A.T. Dinkova-Kostova Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants Proc. Natl. Acad. Sci. U. S. A. 99 2002 11908 11913
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, pp. 11908-11913
-
-
Dinkova-Kostova, A.T.1
-
40
-
-
0242580049
-
Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress
-
D.D. Zhang, and M. Hannink Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress Mol. Cell. Biol. 23 2003 8137 8151
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8137-8151
-
-
Zhang, D.D.1
Hannink, M.2
-
41
-
-
1242296811
-
Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers
-
N. Wakabayashi Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers Proc. Natl. Acad. Sci. U. S. A. 101 2004 2040 2045
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 2040-2045
-
-
Wakabayashi, N.1
-
42
-
-
3543008924
-
Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2
-
A. Kobayashi Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2 Mol. Cell. Biol. 24 2004 7130 7139
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 7130-7139
-
-
Kobayashi, A.1
-
43
-
-
1242274394
-
Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes
-
M. Kang Scaffolding of Keap1 to the actin cytoskeleton controls the function of Nrf2 as key regulator of cytoprotective phase 2 genes Proc. Natl. Acad. Sci. U. S. A. 101 2004 2046 2051
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 2046-2051
-
-
Kang, M.1
-
44
-
-
0037183998
-
The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm
-
L.M. Zipper, and R.T. Mulcahy The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm J. Biol. Chem. 277 2002 36544 36552
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36544-36552
-
-
Zipper, L.M.1
Mulcahy, R.T.2
-
45
-
-
0033731182
-
Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2
-
H.C. Huang Regulation of the antioxidant response element by protein kinase C-mediated phosphorylation of NF-E2-related factor 2 Proc. Natl. Acad. Sci. U. S. A. 97 2000 12475 12480
-
(2000)
Proc. Natl. Acad. Sci. U. S. A.
, vol.97
, pp. 12475-12480
-
-
Huang, H.C.1
-
46
-
-
0037044791
-
Phosphorylation of Nrf2 at Ser40 by protein kinase C regulates antioxidant response element-mediated transcription
-
H.C. Huang Phosphorylation of Nrf2 at Ser40 by protein kinase C regulates antioxidant response element-mediated transcription J. Biol. Chem. 277 2002 42769 42774
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42769-42774
-
-
Huang, H.C.1
-
47
-
-
0242666198
-
40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression
-
40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression J. Biol. Chem. 278 2003 44675 44682
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 44675-44682
-
-
Bloom, D.A.1
Jaiswal, A.K.2
-
48
-
-
0041742490
-
Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress
-
S. Numazawa Atypical protein kinase C mediates activation of NF-E2-related factor 2 in response to oxidative stress Am. J. Physiol. Cell Physiol. 285 2003 C334 C342
-
(2003)
Am. J. Physiol. Cell Physiol.
, vol.285
-
-
Numazawa, S.1
-
49
-
-
0034687543
-
Inhibition of ERK and p38 MAP kinases inhibits binding of Nrf2 and induction of GCS genes
-
L.M. Zipper, and R.T. Mulcahey Inhibition of ERK and p38 MAP kinases inhibits binding of Nrf2 and induction of GCS genes Biochem. Biophys. Res. Commun. 278 2000 484 492
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.278
, pp. 484-492
-
-
Zipper, L.M.1
Mulcahey, R.T.2
-
50
-
-
0034704079
-
Activation of mitogen-activated protein kinases pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanisms
-
R. Yu Activation of mitogen-activated protein kinases pathways induces antioxidant response element-mediated gene expression via a Nrf2-dependent mechanisms J. Biol. Chem. 275 2000 39907 39913
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 39907-39913
-
-
Yu, R.1
-
51
-
-
0038663090
-
Erk activation is required for Nrf2 nuclear localization during pyrrolidine dithiocarbamate induction of glutamate cycteine ligase modulatory gene expression in HepG2 cells
-
L.M. Zipper, and R.T. Mulcahy Erk activation is required for Nrf2 nuclear localization during pyrrolidine dithiocarbamate induction of glutamate cycteine ligase modulatory gene expression in HepG2 cells Toxicol. Sci. 73 2003 124 134
-
(2003)
Toxicol. Sci.
, vol.73
, pp. 124-134
-
-
Zipper, L.M.1
Mulcahy, R.T.2
-
52
-
-
0141567455
-
Involvement of Nrf2 and JNK1 in the activation of antioxidant responsive element (ARE) by chemoprevention agent phenethyl isothiocyanate (PEITC)
-
Y.S. Keum Involvement of Nrf2 and JNK1 in the activation of antioxidant responsive element (ARE) by chemoprevention agent phenethyl isothiocyanate (PEITC) Pharm. Res. 20 2003 1351 1356
-
(2003)
Pharm. Res.
, vol.20
, pp. 1351-1356
-
-
Keum, Y.S.1
-
53
-
-
0035827505
-
Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells
-
J-M. Lee Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells J. Biol. Chem. 276 2001 20011 20016
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 20011-20016
-
-
Lee, J.-M.1
-
54
-
-
0038537298
-
PI3K is a key molecule in the Nrf2-mediated regulation of antioxidative proteins by hemin in human neuroblastoma cells
-
K. Nakaso PI3K is a key molecule in the Nrf2-mediated regulation of antioxidative proteins by hemin in human neuroblastoma cells FEBS Lett. 546 2003 181 184
-
(2003)
FEBS Lett.
, vol.546
, pp. 181-184
-
-
Nakaso, K.1
-
55
-
-
0036840585
-
Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress
-
K.W. Kang Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress Mol. Pharmacol. 62 2002 1001 1010
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 1001-1010
-
-
Kang, K.W.1
-
56
-
-
0141752795
-
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
-
S.B. Cullinan nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival Mol. Cell. Biol. 23 2003 7198 7209
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 7198-7209
-
-
Cullinan, S.B.1
-
57
-
-
2442542312
-
PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress
-
S.B. Cullinan PERK-dependent activation of Nrf2 contributes to redox homeostasis and cell survival following endoplasmic reticulum stress J. Biol. Chem. 279 2004 20108 20117
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20108-20117
-
-
Cullinan, S.B.1
-
58
-
-
2942568014
-
Dietary chemopreventive compounds and ARE/EpRE signaling
-
C. Chen, and A-N.T. Kong Dietary chemopreventive compounds and ARE/EpRE signaling Free Radic. Biol. Med. 36 2004 1505 1516
-
(2004)
Free Radic. Biol. Med.
, vol.36
, pp. 1505-1516
-
-
Chen, C.1
Kong, A-N.T.2
-
59
-
-
4444315787
-
A strategy for cancer prevention: Stimulation of the Nrf2-ARE signaling pathway
-
Y. Zhang, and G.B. Gordon A strategy for cancer prevention: stimulation of the Nrf2-ARE signaling pathway Mol. Cancer Ther. 3 2004 885 892
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 885-892
-
-
Zhang, Y.1
Gordon, G.B.2
-
60
-
-
2342598377
-
Redox ranking of inducers of a cancer-protective enzyme via the energy of their highest occupied molecular orbital
-
V. Zoete Redox ranking of inducers of a cancer-protective enzyme via the energy of their highest occupied molecular orbital Free Radic. Biol. Med. 36 2004 1418 1423
-
(2004)
Free Radic. Biol. Med.
, vol.36
, pp. 1418-1423
-
-
Zoete, V.1
-
61
-
-
0036479330
-
A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway
-
Y. Morimitsu A sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway J. Biol. Chem. 277 2002 3456 3463
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3456-3463
-
-
Morimitsu, Y.1
-
62
-
-
0037569694
-
Curcumin activates the heme oxygenase-1 gene via regulation of Nrf2 and the antioxidant responsive element
-
E. Balogun Curcumin activates the heme oxygenase-1 gene via regulation of Nrf2 and the antioxidant responsive element Biochem. J. 371 2003 887 895
-
(2003)
Biochem. J.
, vol.371
, pp. 887-895
-
-
Balogun, E.1
-
64
-
-
0035823540
-
Induction of cellular antioxidative stress genes through heterodimeric transcription factor Nrf2/Small Maf by antirheumatic gold(I) compounds
-
K. Kataoka Induction of cellular antioxidative stress genes through heterodimeric transcription factor Nrf2/Small Maf by antirheumatic gold(I) compounds J. Biol. Chem. 276 2001 34074 34081
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 34074-34081
-
-
Kataoka, K.1
-
65
-
-
0036318224
-
Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound
-
S. Braun Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound Mol. Cell. Biol. 22 2002 5492 5505
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 5492-5505
-
-
Braun, S.1
-
66
-
-
0037767747
-
Nitric oxide stimulates Nrf2 nuclear translocation in vascular endothelium
-
B.J. Buckley Nitric oxide stimulates Nrf2 nuclear translocation in vascular endothelium Biochem. Biophys. Res. Commun. 307 2003 973 979
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.307
, pp. 973-979
-
-
Buckley, B.J.1
-
67
-
-
2442535969
-
Nitric oxide-induced transcriptional up-regulation of protective genes by Nrf2 via the antioxidant response element counteracts apoptosis of neuroblastoma cells
-
S. Dhakshinamoorthy, and A.G. Porter Nitric oxide-induced transcriptional up-regulation of protective genes by Nrf2 via the antioxidant response element counteracts apoptosis of neuroblastoma cells J. Biol. Chem. 279 2004 20096 20107
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 20096-20107
-
-
Dhakshinamoorthy, S.1
Porter, A.G.2
-
68
-
-
1642540092
-
Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione levels
-
N. Morito Nrf2 regulates the sensitivity of death receptor signals by affecting intracellular glutathione levels Oncogene 22 2003 9275 9281
-
(2003)
Oncogene
, vol.22
, pp. 9275-9281
-
-
Morito, N.1
-
69
-
-
0242721624
-
Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway
-
M-K. Kwak Antioxidants enhance mammalian proteasome expression through the Keap1-Nrf2 signaling pathway Mol. Cell. Biol. 23 2003 8786 8794
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 8786-8794
-
-
Kwak, M.-K.1
-
70
-
-
0842304134
-
Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinine and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult
-
A.D. Kraft Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinine and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult J. Neurosci. 24 2004 1101 1112
-
(2004)
J. Neurosci.
, vol.24
, pp. 1101-1112
-
-
Kraft, A.D.1
|