-
1
-
-
0242363225
-
Identification of the haematopoietic stem cell niche and control of the niche size
-
Zhang J, CNiu, LYe, HHuang, XHe, WGTong, JRoss, JHaug, T Johnson, et al. (2003). Identification of the haematopoietic stem cell niche and control of the niche size. Nature 425:836-841.
-
(2003)
Nature
, vol.425
, pp. 836-841
-
-
Zhang, J.1
Niu, C.2
Ye, L.3
Huang, H.4
He, X.5
Tong, W.G.6
Ross, J.7
Haug, J.8
Johnson, T.9
-
2
-
-
73949121249
-
The hematopoietic stem cell niche: Low in oxygen but a nice place to be
-
Eliasson P and JI Jonsson. (2010). The hematopoietic stem cell niche: low in oxygen but a nice place to be. J Cell Physiol 222:17-22.
-
(2010)
J Cell Physiol
, vol.222
, pp. 17-22
-
-
Eliasson, P.1
Jonsson, J.I.2
-
3
-
-
77956205122
-
The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche
-
Simsek T, F Kocabas, J Zheng, RJ Deberardinis, AI Mahmoud, EN Olson, JW Schneider, CC Zhang and HA Sadek. (2010). The distinct metabolic profile of hematopoietic stem cells reflects their location in a hypoxic niche. Cell Stem Cell 7:380-390.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 380-390
-
-
Simsek, T.1
Kocabas, F.2
Zheng, J.3
Deberardinis, R.J.4
Mahmoud, A.I.5
Olson, E.N.6
Schneider, J.W.7
Zhang, C.C.8
Sadek, H.A.9
-
4
-
-
84878080889
-
Peroxisome proliferator-activated-gamma coactivator-1alpha-mediated mitochondrial biogenesis is important for hematopoietic recovery in response to stress
-
Basu S, HE Broxmeyer and G Hangoc. (2013). Peroxisome proliferator-activated-gamma coactivator-1alpha-mediated mitochondrial biogenesis is important for hematopoietic recovery in response to stress. Stem cells Dev 22:1678-1692.
-
(2013)
Stem Cells Dev
, vol.22
, pp. 1678-1692
-
-
Basu, S.1
Broxmeyer, H.E.2
Hangoc, G.3
-
5
-
-
79955698235
-
Accumulating mitochondrial DNA mutations drive premature hema-topoietic aging phenotypes distinct from physiological stem cell aging
-
Norddahl GL, CJ Pronk, M Wahlestedt, G Sten, JM Nygren, A Ugale, M Sigvardsson and D Bryder. (2011). Accumulating mitochondrial DNA mutations drive premature hema-topoietic aging phenotypes distinct from physiological stem cell aging. Cell Stem Cell 8:499-510.
-
(2011)
Cell Stem Cell
, vol.8
, pp. 499-510
-
-
Norddahl, G.L.1
Pronk, C.J.2
Wahlestedt, M.3
Sten, G.4
Nygren, J.M.5
Ugale, A.6
Sigvardsson, M.7
Bryder, D.8
-
6
-
-
84879559313
-
Cord blood-derived CD34+ hematopoietic cells with low mitochondrial mass are enriched in hematopoietic re-populating stem cell function
-
Romero-Moya D, C Bueno, R Montes, O Navarro-Montero, FJ Iborra, LC Lopez, M Martin and P Menendez. (2013). Cord blood-derived CD34+ hematopoietic cells with low mitochondrial mass are enriched in hematopoietic re-populating stem cell function. Haematologica 98:1022-1029.
-
(2013)
Haematologica
, vol.98
, pp. 1022-1029
-
-
Romero-Moya, D.1
Bueno, C.2
Montes, R.3
Navarro-Montero, O.4
Iborra, F.J.5
Lopez, L.C.6
Martin, M.7
Menendez, P.8
-
7
-
-
33645730667
-
Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells
-
Ito K, A Hirao, F Arai, K Takubo, S Matsuoka, K Miyamoto, M Ohmura, K Naka, K Hosokawa, Y Ikeda and T Suda. (2006). Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. Nat Med 12:446-451.
-
(2006)
Nat Med
, vol.12
, pp. 446-451
-
-
Ito, K.1
Hirao, A.2
Arai, F.3
Takubo, K.4
Matsuoka, S.5
Miyamoto, K.6
Ohmura, M.7
Naka, K.8
Hosokawa, K.9
Ikeda, Y.10
Suda, T.11
-
8
-
-
35548936968
-
A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche
-
Jang YY and SJ Sharkis. (2007). A low level of reactive oxygen species selects for primitive hematopoietic stem cells that may reside in the low-oxygenic niche. Blood 110:3056-3063.
-
(2007)
Blood
, vol.110
, pp. 3056-3063
-
-
Jang, Y.Y.1
Sharkis, S.J.2
-
9
-
-
77956217067
-
Regulation of the HIF-1alpha level is essential for hematopoietic stem cells
-
Takubo K, N Goda, W Yamada, H Iriuchishima, E Ikeda, Y Kubota, H Shima, RS Johnson, A Hirao, M Suematsu and T Suda. (2010). Regulation of the HIF-1alpha level is essential for hematopoietic stem cells. Cell Stem Cell 7:391-402.
-
(2010)
Cell Stem Cell
, vol.7
, pp. 391-402
-
-
Takubo, K.1
Goda, N.2
Yamada, W.3
Iriuchishima, H.4
Ikeda, E.5
Kubota, Y.6
Shima, H.7
Johnson, R.S.8
Hirao, A.9
Suematsu, M.10
Suda, T.11
-
10
-
-
80053926733
-
Cripto regulates hematopoi-etic stem cells as a hypoxic-niche-related factor through cell surface receptor GRP78
-
Miharada K, G Karlsson, M Rehn, E Rorby, K Siva, J Cam-menga and S Karlsson. (2011). Cripto regulates hematopoi-etic stem cells as a hypoxic-niche-related factor through cell surface receptor GRP78. Cell Stem Cell 9:330-344.
-
(2011)
Cell Stem Cell
, vol.9
, pp. 330-344
-
-
Miharada, K.1
Karlsson, G.2
Rehn, M.3
Rorby, E.4
Siva, K.5
Cam-Menga, J.6
Karlsson, S.7
-
11
-
-
84870981340
-
Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress
-
Unnisa Z, JP Clark, J Roychoudhury, E Thomas, L Tessar-ollo, NG Copeland, NA Jenkins, HL Grimes and AR Kumar. (2012). Meis1 preserves hematopoietic stem cells in mice by limiting oxidative stress. Blood 120:4973-4981.
-
(2012)
Blood
, vol.120
, pp. 4973-4981
-
-
Unnisa, Z.1
Clark, J.P.2
Roychoudhury, J.3
Thomas, E.4
Tessar-Ollo, L.5
Copeland, N.G.6
Jenkins, N.A.7
Grimes, H.L.8
Kumar, A.R.9
-
12
-
-
84871001227
-
Meis1 regulates the metabolic phenotype and oxidant defense of he-matopoietic stem cells
-
Kocabas F, J Zheng, S Thet, NG Copeland, NA Jenkins, RJ DeBerardinis, C Zhang and HA Sadek. (2012). Meis1 regulates the metabolic phenotype and oxidant defense of he-matopoietic stem cells. Blood 120:4963-4972.
-
(2012)
Blood
, vol.120
, pp. 4963-4972
-
-
Kocabas, F.1
Zheng, J.2
Thet, S.3
Copeland, N.G.4
Jenkins, N.A.5
Deberardinis, R.J.6
Zhang, C.7
Sadek, H.A.8
-
13
-
-
84872011926
-
Regulation of glycolysis by pdk functions as a metabolic checkpoint for cell cycle quiescence in he-matopoietic stem cells
-
Takubo K, G Nagamatsu, CI Kobayashi, A Nakamura-Ishizu, H Kobayashi, E Ikeda, N Goda, Y Rahimi, RS Johnson, et al. (2013). Regulation of glycolysis by pdk functions as a metabolic checkpoint for cell cycle quiescence in he-matopoietic stem cells. Cell Stem Cell 12:49-61.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 49-61
-
-
Takubo, K.1
Nagamatsu, G.2
Kobayashi, C.I.3
Nakamura-Ishizu, A.4
Kobayashi, H.5
Ikeda, E.6
Goda, N.7
Rahimi, Y.8
Johnson, R.S.9
-
14
-
-
33646376411
-
Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
-
Yilmaz OH, R Valdez, BK Theisen, W Guo, DO Ferguson, H Wu and SJ Morrison. (2006). Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. Nature 441:475-482.
-
(2006)
Nature
, vol.441
, pp. 475-482
-
-
Yilmaz, O.H.1
Valdez, R.2
Theisen, B.K.3
Guo, W.4
Ferguson, D.O.5
Wu, H.6
Morrison, S.J.7
-
15
-
-
33646351002
-
PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention
-
Zhang J, JC Grindley, T Yin, S Jayasinghe, XC He, JT Ross, JS Haug, D Rupp, KS Porter-Westpfahl, et al. (2006). PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention. Nature 441:518-522.
-
(2006)
Nature
, vol.441
, pp. 518-522
-
-
Zhang, J.1
Grindley, J.C.2
Yin, T.3
Jayasinghe, S.4
He, X.C.5
Ross, J.T.6
Haug, J.S.7
Rupp, D.8
Porter-Westpfahl, K.S.9
-
16
-
-
53349091768
-
TSC-mTOR maintains quiescence and function of he-matopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species
-
Chen C, Y Liu, R Liu, T Ikenoue, KL Guan and P Zheng. (2008). TSC-mTOR maintains quiescence and function of he-matopoietic stem cells by repressing mitochondrial biogenesis and reactive oxygen species. J Exp Med 205:2397-2408.
-
(2008)
J Exp Med
, vol.205
, pp. 2397-2408
-
-
Chen, C.1
Liu, Y.2
Liu, R.3
Ikenoue, T.4
Guan, K.L.5
Zheng, P.6
-
17
-
-
58049196780
-
MTORC1-dependent and-independent regulation of stem cell renewal, differentiation, and mobilization
-
Gan B, E Sahin, S Jiang, A Sanchez-Aguilera, KL Scott, L Chin, DA Williams, DJ Kwiatkowski and RA DePinho. (2008). mTORC1-dependent and-independent regulation of stem cell renewal, differentiation, and mobilization. Proc Natl Acad Sci U S A 105:19384-19389.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 19384-19389
-
-
Gan, B.1
Sahin, E.2
Jiang, S.3
Sanchez-Aguilera, A.4
Scott, K.L.5
Chin, L.6
Williams, D.A.7
Kwiatkowski, D.J.8
Depinho, R.A.9
-
18
-
-
70350729488
-
Overexpression of Rheb2 enhances mouse hemato-poietic progenitor cell growth while impairing stem cell repopulation
-
Campbell TB, S Basu, G Hangoc, W Tao and HE Broxmeyer. (2009). Overexpression of Rheb2 enhances mouse hemato-poietic progenitor cell growth while impairing stem cell repopulation. Blood 114:3392-3401.
-
(2009)
Blood
, vol.114
, pp. 3392-3401
-
-
Campbell, T.B.1
Basu, S.2
Hangoc, G.3
Tao, W.4
Broxmeyer, H.E.5
-
19
-
-
84870866912
-
Maintenance of hemato-poietic stem cells through regulation of Wnt and mTOR pathways
-
Huang J, M Nguyen-McCarty, EO Hexner, G Danet-Desnoyers and PS Klein. (2012). Maintenance of hemato-poietic stem cells through regulation of Wnt and mTOR pathways. Nat Med 18:1778-1785.
-
(2012)
Nat Med
, vol.18
, pp. 1778-1785
-
-
Huang, J.1
Nguyen-Mccarty, M.2
Hexner, E.O.3
Danet-Desnoyers, G.4
Klein, P.S.5
-
20
-
-
84866082606
-
MTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis
-
Kalaitzidis D, SM Sykes, Z Wang, N Punt, Y Tang, C Ragu, AU Sinha, SW Lane, AL Souza, et al. (2012). mTOR complex 1 plays critical roles in hematopoiesis and Pten-loss-evoked leukemogenesis. Cell Stem Cell 11:429-439.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 429-439
-
-
Kalaitzidis, D.1
Sykes, S.M.2
Wang, Z.3
Punt, N.4
Tang, Y.5
Ragu, C.6
Sinha, A.U.7
Lane, S.W.8
Souza, A.L.9
-
21
-
-
77953283847
-
AKT1 and AKT2 maintain he-matopoietic stem cell function by regulating reactive oxygen species
-
Juntilla MM, VD Patil, M Calamito, RP Joshi, MJ Birnbaum and GA Koretzky. (2010). AKT1 and AKT2 maintain he-matopoietic stem cell function by regulating reactive oxygen species. Blood 115:4030-4038.
-
(2010)
Blood
, vol.115
, pp. 4030-4038
-
-
Juntilla, M.M.1
Patil, V.D.2
Calamito, M.3
Joshi, R.P.4
Birnbaum, M.J.5
Koretzky, G.A.6
-
22
-
-
77949900650
-
Con-stitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice
-
Kharas MG, R Okabe, JJ Ganis, M Gozo, T Khandan, M Paktinat, DG Gilliland and K Gritsman. (2010). Con-stitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice. Blood 115:1406-1415.
-
(2010)
Blood
, vol.115
, pp. 1406-1415
-
-
Kharas, M.G.1
Okabe, R.2
Ganis, J.J.3
Gozo, M.4
Khandan, T.5
Paktinat, M.6
Gilliland, D.G.7
Gritsman, K.8
-
23
-
-
34249882777
-
Foxo3a is essential for maintenance of the hematopoietic stem cell pool
-
Miyamoto K, KY Araki, K Naka, F Arai, K Takubo, S Yamazaki, S Matsuoka, T Miyamoto, K Ito, et al. (2007). Foxo3a is essential for maintenance of the hematopoietic stem cell pool. Cell Stem Cell 1:101-112.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 101-112
-
-
Miyamoto, K.1
Araki, K.Y.2
Naka, K.3
Arai, F.4
Takubo, K.5
Yamazaki, S.6
Matsuoka, S.7
Miyamoto, T.8
Ito, K.9
-
24
-
-
33846419112
-
FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress
-
Tothova Z, R Kollipara, BJ Huntly, BH Lee, DH Castrillon, DE Cullen, EP McDowell, S Lazo-Kallanian, IR Williams, et al. (2007). FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress. Cell 128:325-339.
-
(2007)
Cell
, vol.128
, pp. 325-339
-
-
Tothova, Z.1
Kollipara, R.2
Huntly, B.J.3
Lee, B.H.4
Castrillon, D.H.5
Cullen, D.E.6
McDowell, E.P.7
Lazo-Kallanian, S.8
Williams, I.R.9
-
25
-
-
78649851511
-
The Lkb1 metabolic sensor maintains haematopoietic stem cell survival
-
Gurumurthy S, SZ Xie, B Alagesan, J Kim, RZ Yusuf, B Saez, A Tzatsos, F Ozsolak, P Milos, et al. (2010). The Lkb1 metabolic sensor maintains haematopoietic stem cell survival. Nature 468:659-663.
-
(2010)
Nature
, vol.468
, pp. 659-663
-
-
Gurumurthy, S.1
Xie, S.Z.2
Alagesan, B.3
Kim, J.4
Yusuf, R.Z.5
Saez, B.6
Tzatsos, A.7
Ozsolak, F.8
Milos, P.9
-
26
-
-
78649811793
-
Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells
-
Nakada D, TL Saunders and SJ Morrison. (2010). Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells. Nature 468:653-658.
-
(2010)
Nature
, vol.468
, pp. 653-658
-
-
Nakada, D.1
Saunders, T.L.2
Morrison, S.J.3
-
27
-
-
78649874959
-
Lkb1 regulates quiescence and metabolic homeosta-sis of haematopoietic stem cells
-
Gan B, J Hu, S Jiang, Y Liu, E Sahin, L Zhuang, E Fletcher-Sananikone, S Colla, YA Wang, L Chin and RA Depinho. (2010). Lkb1 regulates quiescence and metabolic homeosta-sis of haematopoietic stem cells. Nature 468:701-704.
-
(2010)
Nature
, vol.468
, pp. 701-704
-
-
Gan, B.1
Hu, J.2
Jiang, S.3
Liu, Y.4
Sahin, E.5
Zhuang, L.6
Fletcher-Sananikone, E.7
Colla, S.8
Wang, Y.A.9
Chin, L.10
Depinho, R.A.11
-
28
-
-
84868632060
-
A PML-PPAR-delta pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance
-
Ito K, A Carracedo, D Weiss, F Arai, U Ala, DE Avigan, ZT Schafer, RM Evans, T Suda, CH Lee and PP Pandolfi. (2012). A PML-PPAR-delta pathway for fatty acid oxidation regulates hematopoietic stem cell maintenance. Nat Med 18: 1350-1358.
-
(2012)
Nat Med
, vol.18
, pp. 1350-1358
-
-
Ito, K.1
Carracedo, A.2
Weiss, D.3
Arai, F.4
Ala, U.5
Avigan, D.E.6
Schafer, Z.T.7
Evans, R.M.8
Suda, T.9
Lee, C.H.10
Pandolfi, P.P.11
-
29
-
-
84872037830
-
Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation
-
Yu WM, X Liu, J Shen, O Jovanovic, EE Pohl, SL Gerson, T Finkel, HE Broxmeyer and CK Qu. (2013). Metabolic regulation by the mitochondrial phosphatase PTPMT1 is required for hematopoietic stem cell differentiation. Cell Stem Cell 12:62-74.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 62-74
-
-
Yu, W.M.1
Liu, X.2
Shen, J.3
Jovanovic, O.4
Pohl, E.E.5
Gerson, S.L.6
Finkel, T.7
Broxmeyer, H.E.8
Qu, C.K.9
-
30
-
-
0001190221
-
MRG1, the product of a melanocyte-specific gene related gene, is a cytokine-inducible transcription factor with transformation activity
-
Sun HB, YX Zhu, T Yin, G Sledge and YC Yang. (1998). MRG1, the product of a melanocyte-specific gene related gene, is a cytokine-inducible transcription factor with transformation activity. Proc Natl Acad Sci U S A 95:13555-13560.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 13555-13560
-
-
Sun, H.B.1
Zhu, Y.X.2
Yin, T.3
Sledge, G.4
Yang, Y.C.5
-
31
-
-
0032900610
-
Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1
-
Bhattacharya S, CL Michels, MK Leung, ZP Arany, AL Kung and DM Livingston. (1999). Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1. Genes Dev 13:64-75.
-
(1999)
Genes Dev
, vol.13
, pp. 64-75
-
-
Bhattacharya, S.1
Michels, C.L.2
Leung, M.K.3
Arany, Z.P.4
Kung, A.L.5
Livingston, D.M.6
-
32
-
-
18344389337
-
Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator
-
Bamforth SD, J Braganca, JJ Eloranta, JN Murdoch, FI Marques, KR Kranc, H Farza, DJ Henderson, HC Hurst and S Bhattacharya. (2001). Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator. Nat Genet 29:469-474.
-
(2001)
Nat Genet
, vol.29
, pp. 469-474
-
-
Bamforth, S.D.1
Braganca, J.2
Eloranta, J.J.3
Murdoch, J.N.4
Marques, F.I.5
Kranc, K.R.6
Farza, H.7
Henderson, D.J.8
Hurst, H.C.9
Bhattacharya, S.10
-
33
-
-
0036679122
-
The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation
-
Yin Z, J Haynie, X Yang, B Han, S Kiatchoosakun, J Restivo, S Yuan, NR Prabhakar, K Herrup, et al. (2002). The essential role of Cited2, a negative regulator for HIF-1alpha, in heart development and neurulation. Proc Natl Acad Sci U S A 99:10488-10493.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 10488-10493
-
-
Yin, Z.1
Haynie, J.2
Yang, X.3
Han, B.4
Kiatchoosakun, S.5
Restivo, J.6
Yuan, S.7
Prabhakar, N.R.8
Herrup, K.9
-
34
-
-
16544377641
-
Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway
-
Bamforth SD, J Braganca, CR Farthing, JE Schneider, C Broadbent, AC Michell, K Clarke, S Neubauer, D Norris, et al. (2004). Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway. Nat Genet 36:1189-1196.
-
(2004)
Nat Genet
, vol.36
, pp. 1189-1196
-
-
Bamforth, S.D.1
Braganca, J.2
Farthing, C.R.3
Schneider, J.E.4
Broadbent, C.5
Michell, A.C.6
Clarke, K.7
Neubauer, S.8
Norris, D.9
-
35
-
-
17244379390
-
Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development
-
Weninger WJ, K Lopes Floro, MB Bennett, SL Withington, JI Preis, JP Barbera, TJ Mohun and SL Dunwoodie. (2005). Cited2 is required both for heart morphogenesis and establishment of the left-right axis in mouse development. Development 132:1337-1348.
-
(2005)
Development
, vol.132
, pp. 1337-1348
-
-
Weninger, W.J.1
Lopes Floro, K.2
Bennett, M.B.3
Withington, S.L.4
Preis, J.I.5
Barbera, J.P.6
Mohun, T.J.7
Dunwoodie, S.L.8
-
36
-
-
35648939343
-
Cited2, a coactivator of HNF4alpha, is essential for liver development
-
Qu X, E Lam, YQ Doughman, Y Chen, YT Chou, M Lam, M Turakhia, SL Dunwoodie, M Watanabe, et al. (2007). Cited2, a coactivator of HNF4alpha, is essential for liver development. EMBO J 26:4445-4456.
-
(2007)
EMBO J
, vol.26
, pp. 4445-4456
-
-
Qu, X.1
Lam, E.2
Doughman, Y.Q.3
Chen, Y.4
Chou, Y.T.5
Lam, M.6
Turakhia, M.7
Dunwoodie, S.L.8
Watanabe, M.9
-
37
-
-
0033579430
-
MRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone alpha-subunit gene expression
-
Glenn DJ and RA Maurer. (1999). MRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone alpha-subunit gene expression. J Biol Chem 274:36159-36167.
-
(1999)
J Biol Chem
, vol.274
, pp. 36159-36167
-
-
Glenn, D.J.1
Maurer, R.A.2
-
38
-
-
35548948518
-
Cited2 is required for normal hematopoiesis in the murine fetal liver
-
Chen Y, P Haviernik, KD Bunting and YC Yang. (2007). Cited2 is required for normal hematopoiesis in the murine fetal liver. Blood 110:2889-2898.
-
(2007)
Blood
, vol.110
, pp. 2889-2898
-
-
Chen, Y.1
Haviernik, P.2
Bunting, K.D.3
Yang, Y.C.4
-
39
-
-
70450253358
-
Cited2 is an essential regulator of adult hematopoietic stem cells
-
Kranc KR, H Schepers, NP Rodrigues, S Bamforth, E Villadsen, H Ferry, T Bouriez-Jones, M Sigvardsson, S Bhattacharya, SE Jacobsen and T Enver. (2009). Cited2 is an essential regulator of adult hematopoietic stem cells. Cell Stem Cell 5:659-665.
-
(2009)
Cell Stem Cell
, vol.5
, pp. 659-665
-
-
Kranc, K.R.1
Schepers, H.2
Rodrigues, N.P.3
Bamforth, S.4
Villadsen, E.5
Ferry, H.6
Bouriez-Jones, T.7
Sigvardsson, M.8
Bhattacharya, S.9
Jacobsen, S.E.10
Enver, T.11
-
40
-
-
84863376354
-
HIF-1alpha deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency
-
Du J, Y Chen, Q Li, X Han, C Cheng, Z Wang, D Danielpour, SL Dunwoodie, KD Bunting and YC Yang. (2012). HIF-1alpha deletion partially rescues defects of hematopoietic stem cell quiescence caused by Cited2 deficiency. Blood 119:2789-2798.
-
(2012)
Blood
, vol.119
, pp. 2789-2798
-
-
Du, J.1
Chen, Y.2
Li, Q.3
Han, X.4
Cheng, C.5
Wang, Z.6
Danielpour, D.7
Dunwoodie, S.L.8
Bunting, K.D.9
Yang, Y.C.10
-
41
-
-
84865204039
-
Cited2 controls pluripotency and cardiomyocyte differentiation of murine embryonic stem cells through Oct4
-
Li Q, DL Ramirez-Bergeron, SL Dunwoodie and YC Yang. (2012). Cited2 controls pluripotency and cardiomyocyte differentiation of murine embryonic stem cells through Oct4. J Biol Chem 287:29088-29100.
-
(2012)
J Biol Chem
, vol.287
, pp. 29088-29100
-
-
Li, Q.1
Ramirez-Bergeron, D.L.2
Dunwoodie, S.L.3
Yang, Y.C.4
-
42
-
-
20044363097
-
Gene expression profile of murine long-term reconstituting vs. Short-term reconstituting hematopoietic stem cells
-
Zhong JF, Y Zhao, S Sutton, A Su, Y Zhan, L Zhu, C Yan, T Gallaher, PB Johnston, WF Anderson and MP Cooke. (2005). Gene expression profile of murine long-term reconstituting vs. short-term reconstituting hematopoietic stem cells. Proc Natl Acad Sci U S A 102:2448-2453.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 2448-2453
-
-
Zhong, J.F.1
Zhao, Y.2
Sutton, S.3
Su, A.4
Zhan, Y.5
Zhu, L.6
Yan, C.7
Gallaher, T.8
Johnston, P.B.9
Anderson, W.F.10
Cooke, M.P.11
-
43
-
-
5444224643
-
Efficacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues
-
Pendergrass W, N Wolf and M Poot. (2004). Efficacy of MitoTracker Green and CMXrosamine to measure changes in mitochondrial membrane potentials in living cells and tissues. Cytometry A 61:162-169.
-
(2004)
Cytometry A
, vol.61
, pp. 162-169
-
-
Pendergrass, W.1
Wolf, N.2
Poot, M.3
-
44
-
-
0022852609
-
Quantitative analysis of cellular glutathione by flow cytometry utilizing monochlorobimane: Some applications to radiation and drug resistance in vitro and in vivo
-
Rice GC, EA Bump, DC Shrieve, W Lee and M Kovacs. (1986). Quantitative analysis of cellular glutathione by flow cytometry utilizing monochlorobimane: some applications to radiation and drug resistance in vitro and in vivo. Cancer Res 46:6105-6110.
-
(1986)
Cancer Res
, vol.46
, pp. 6105-6110
-
-
Rice, G.C.1
Bump, E.A.2
Shrieve, D.C.3
Lee, W.4
Kovacs, M.5
-
45
-
-
0028325262
-
Evaluation of methods for measuring cellular glutathione content using flow cytome-try
-
Hedley DW and S Chow. (1994). Evaluation of methods for measuring cellular glutathione content using flow cytome-try. Cytometry 15:349-358.
-
(1994)
Cytometry
, vol.15
, pp. 349-358
-
-
Hedley, D.W.1
Chow, S.2
-
46
-
-
52049085061
-
Metabolomic and mass isotopomer analysis of liver gluconeogenesis and citric acid cycle: II. Heterogeneity of metabolite labeling pattern
-
Yang L, T Kasumov, RS Kombu, SH Zhu, AV Cendrowski, F David, VE Anderson, JK Kelleher and H Brunengraber. (2008). Metabolomic and mass isotopomer analysis of liver gluconeogenesis and citric acid cycle: II. Heterogeneity of metabolite labeling pattern. J Biol Chem 283:21988-21996.
-
(2008)
J Biol Chem
, vol.283
, pp. 21988-21996
-
-
Yang, L.1
Kasumov, T.2
Kombu, R.S.3
Zhu, S.H.4
Cendrowski, A.V.5
David, F.6
Anderson, V.E.7
Kelleher, J.K.8
Brunengraber, H.9
-
47
-
-
81155132236
-
Peroxisome proliferator-activated receptor gamma (PPARgamma) mediates a Ski oncogene-induced shift from glycolysis to oxidative energy metabolism
-
Ye F, H Lemieux, CL Hoppel, RW Hanson, P Hakimi, CM Croniger, M Puchowicz, VE Anderson, H Fujioka and E Stavnezer. (2011). Peroxisome proliferator-activated receptor gamma (PPARgamma) mediates a Ski oncogene-induced shift from glycolysis to oxidative energy metabolism. J Biol Chem 286:40013-40024.
-
(2011)
J Biol Chem
, vol.286
, pp. 40013-40024
-
-
Ye, F.1
Lemieux, H.2
Hoppel, C.L.3
Hanson, R.W.4
Hakimi, P.5
Croniger, C.M.6
Puchowicz, M.7
Anderson, V.E.8
Fujioka, H.9
Stavnezer, E.10
-
48
-
-
84874192375
-
FOXO3A directs a protective autophagy program in haematopoietic stem cells
-
Warr MR, M Binnewies, J Flach, D Reynaud, T Garg, R Malhotra, J Debnath and E Passegue. (2013). FOXO3A directs a protective autophagy program in haematopoietic stem cells. Nature 494:323-327.
-
(2013)
Nature
, vol.494
, pp. 323-327
-
-
Warr, M.R.1
Binnewies, M.2
Flach, J.3
Reynaud, D.4
Garg, T.5
Malhotra, R.6
Debnath, J.7
Passegue, E.8
-
49
-
-
84860531487
-
HIF1alpha induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition
-
Zhou W, M Choi, D Margineantu, L Margaretha, J Hesson, C Cavanaugh, CA Blau, MS Horwitz, D Hockenbery, C Ware and H Ruohola-Baker. (2012). HIF1alpha induced switch from bivalent to exclusively glycolytic metabolism during ESC-to-EpiSC/hESC transition. EMBO J 31:2103-2116.
-
(2012)
EMBO J
, vol.31
, pp. 2103-2116
-
-
Zhou, W.1
Choi, M.2
Margineantu, D.3
Margaretha, L.4
Hesson, J.5
Cavanaugh, C.6
Blau, C.A.7
Horwitz, M.S.8
Hockenbery, D.9
Ware, C.10
Ruohola-Baker, H.11
-
50
-
-
84055178474
-
Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks
-
Magnuson B, B Ekim and DC Fingar. (2012). Regulation and function of ribosomal protein S6 kinase (S6K) within mTOR signalling networks. Biochem J 441:1-21.
-
(2012)
Biochem J
, vol.441
, pp. 1-21
-
-
Magnuson, B.1
Ekim, B.2
Fingar, D.C.3
-
51
-
-
0142200472
-
Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation
-
Furuyama T, K Kitayama, H Yamashita and N Mori. (2003). Forkhead transcription factor FOXO1 (FKHR)-dependent induction of PDK4 gene expression in skeletal muscle during energy deprivation. Biochem J 375:365-371.
-
(2003)
Biochem J
, vol.375
, pp. 365-371
-
-
Furuyama, T.1
Kitayama, K.2
Yamashita, H.3
Mori, N.4
-
52
-
-
33749338109
-
Insulin regulation of skeletal muscle PDK4 mRNA expression is impaired in acute insulin-resistant states
-
Kim YI, FN Lee, WS Choi, S Lee and JH Youn. (2006). Insulin regulation of skeletal muscle PDK4 mRNA expression is impaired in acute insulin-resistant states. Diabetes 55:2311-2317.
-
(2006)
Diabetes
, vol.55
, pp. 2311-2317
-
-
Kim, Y.I.1
Lee, F.N.2
Choi, W.S.3
Lee, S.4
Youn, J.H.5
-
53
-
-
47249119658
-
CD36-dependent regulation of muscle FoxO1 and PDK4 in the PPAR delta/beta-mediated adaptation to metabolic stress
-
Nahle Z, M Hsieh, T Pietka, CT Coburn, PA Grimaldi, MQ Zhang, D Das and NA Abumrad. (2008). CD36-dependent regulation of muscle FoxO1 and PDK4 in the PPAR delta/beta-mediated adaptation to metabolic stress. J Biol Chem 283:14317-14326.
-
(2008)
J Biol Chem
, vol.283
, pp. 14317-14326
-
-
Nahle, Z.1
Hsieh, M.2
Pietka, T.3
Coburn, C.T.4
Grimaldi, P.A.5
Zhang, M.Q.6
Das, D.7
Abumrad, N.A.8
-
54
-
-
78751485448
-
Insulin receptor substrates Irs1 and Irs2 coordinate skeletal muscle growth and metabolism via the Akt and AMPK pathways
-
Long YC, Z Cheng, KD Copps and MF White. (2011). Insulin receptor substrates Irs1 and Irs2 coordinate skeletal muscle growth and metabolism via the Akt and AMPK pathways. Mol Cell Biol 31:430-441.
-
(2011)
Mol Cell Biol
, vol.31
, pp. 430-441
-
-
Long, Y.C.1
Cheng, Z.2
Copps, K.D.3
White, M.F.4
-
55
-
-
84858959012
-
Autophagy in premature senescent cells is activated via AMPK pathway
-
Guo L, B Xie and Z Mao. (2012). Autophagy in premature senescent cells is activated via AMPK pathway. Int J Mol Sci 13:3563-3582.
-
(2012)
Int J Mol Sci
, vol.13
, pp. 3563-3582
-
-
Guo, L.1
Xie, B.2
Mao, Z.3
-
56
-
-
77955273858
-
Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells
-
Inoue S, S Noda, K Kashima, K Nakada, J Hayashi and H Miyoshi. (2010). Mitochondrial respiration defects modulate differentiation but not proliferation of hematopoietic stem and progenitor cells. FEBS Lett 584:3402-3409.
-
(2010)
FEBS Lett
, vol.584
, pp. 3402-3409
-
-
Inoue, S.1
Noda, S.2
Kashima, K.3
Nakada, K.4
Hayashi, J.5
Miyoshi, H.6
-
57
-
-
77954878639
-
Enhanced oxidative stress and increased mitochondrial mass during efavirenz-induced apoptosis in human hepatic cells
-
Apostolova N, LJ Gomez-Sucerquia, A Moran, A Alvarez, A Blas-Garcia and JV Esplugues. (2010). Enhanced oxidative stress and increased mitochondrial mass during efavirenz-induced apoptosis in human hepatic cells. Br J Pharmacol 160:2069-2084.
-
(2010)
Br J Pharmacol
, vol.160
, pp. 2069-2084
-
-
Apostolova, N.1
Gomez-Sucerquia, L.J.2
Moran, A.3
Alvarez, A.4
Blas-Garcia, A.5
Esplugues, J.V.6
-
58
-
-
84876909069
-
The ageing haematopoietic stem cell compartment
-
Geiger H, G de Haan and MC Florian. (2013). The ageing haematopoietic stem cell compartment. Nat Rev Immunol 13:376-389.
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 376-389
-
-
Geiger, H.1
De Haan, G.2
Florian, M.C.3
-
59
-
-
77950630969
-
Growth factor erv1-like modulates Drp1 to preserve mitochondrial dynamics and function in mouse embryonic stem cells
-
Todd LR, MN Damin, R Gomathinayagam, SR Horn, AR Means and U Sankar. (2010). Growth factor erv1-like modulates Drp1 to preserve mitochondrial dynamics and function in mouse embryonic stem cells. Mol Biol Cell 21:1225-1236.
-
(2010)
Mol Biol Cell
, vol.21
, pp. 1225-1236
-
-
Todd, L.R.1
Damin, M.N.2
Gomathinayagam, R.3
Horn, S.R.4
Means, A.R.5
Sankar, U.6
-
60
-
-
84868347607
-
Metabolic plasticity in stem cell homeostasis and differentiation
-
Folmes CD, PP Dzeja, TJ Nelson and A Terzic. (2012). Metabolic plasticity in stem cell homeostasis and differentiation. Cell Stem Cell 11:596-606.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 596-606
-
-
Folmes, C.D.1
Dzeja, P.P.2
Nelson, T.J.3
Terzic, A.4
-
61
-
-
80052775605
-
Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice
-
Yu X, N Shen, ML Zhang, FY Pan, C Wang, WP Jia, C Liu, Q Gao, X Gao, B Xue and CJ Li. (2011). Egr-1 decreases adipocyte insulin sensitivity by tilting PI3K/Akt and MAPK signal balance in mice. EMBO J 30:3754-3765.
-
(2011)
EMBO J
, vol.30
, pp. 3754-3765
-
-
Yu, X.1
Shen, N.2
Zhang, M.L.3
Pan, F.Y.4
Wang, C.5
Jia, W.P.6
Liu, C.7
Gao, Q.8
Gao, X.9
Xue, B.10
Li, C.J.11
-
62
-
-
84855878565
-
P53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2
-
Contractor T and CR Harris. (2012). p53 negatively regulates transcription of the pyruvate dehydrogenase kinase Pdk2. Cancer Res 72:560-567.
-
(2012)
Cancer Res
, vol.72
, pp. 560-567
-
-
Contractor, T.1
Harris, C.R.2
-
63
-
-
37349025432
-
FOXO3a is activated inresponse tohypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2
-
Bakker WJ, IS Harris and TW Mak. (2007). FOXO3a is activated inresponse tohypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2. Mol Cell 28:941-953.
-
(2007)
Mol Cell
, vol.28
, pp. 941-953
-
-
Bakker, W.J.1
Harris, I.S.2
Mak, T.W.3
-
64
-
-
84875143073
-
BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells
-
Lagadinou ED, A Sach, K Callahan, RM Rossi, SJ Neering, M Minhajuddin, JM Ashton, S Pei, V Grose, et al. (2013). BCL-2 inhibition targets oxidative phosphorylation and selectively eradicates quiescent human leukemia stem cells. Cell Stem Cell 12:329-341.
-
(2013)
Cell Stem Cell
, vol.12
, pp. 329-341
-
-
Lagadinou, E.D.1
Sach, A.2
Callahan, K.3
Rossi, R.M.4
Neering, S.J.5
Minhajuddin, M.6
Ashton, J.M.7
Pei, S.8
Grose, V.9
-
65
-
-
77955134007
-
Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: Report from the International Microarray Innovations in Leukemia Study Group
-
Haferlach T, A Kohlmann, L Wieczorek, G Basso, GT Kronnie, MC Bene, J De Vos, JM Hernandez, WK Hofmann, et al. (2010). Clinical utility of microarray-based gene expression profiling in the diagnosis and subclassification of leukemia: report from the International Microarray Innovations in Leukemia Study Group. J Clin Oncol 28:2529-2537.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2529-2537
-
-
Haferlach, T.1
Kohlmann, A.2
Wieczorek, L.3
Basso, G.4
Kronnie, G.T.5
Bene, M.C.6
De Vos, J.7
Hernandez, J.M.8
Hofmann, W.K.9
|