Lkb1 regulates quiescence and metabolic homeostasis of haematopoietic stem cells

Nature

Volumn 468, Issue 7324, 2010, Pages 701-704

  Gan, Boyi ^a,b   Hu, Jian ^a,b   Jiang, Shan ^a,b   Liu, Yingchun ^a,b   Sahin, Ergün ^a,b   Zhuang, Li ^a,b   Fletcher Sananikone, Eliot ^a,b   Colla, Simona ^a,b   Wang, Y Alan ^a,b   Chin, Lynda ^a,b   Depinho, Ronald A ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1BETA; PROTEIN KINASE LKB1;

APOPTOSIS; ENERGY USE; ENZYME ACTIVITY; HEMATOLOGY; HOMEOSTASIS; METABOLISM; MITOCHONDRION; PROTEIN;

ACUTE STRESS; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BIOGENESIS; CELL ENERGY; CELL METABOLISM; CELL POPULATION; CELL PROLIFERATION; CELL REGENERATION; CELL SURVIVAL; DOWN REGULATION; ENERGY METABOLISM; EUKARYOTIC CELL; GENE DELETION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; HOMEOSTASIS; LETHALITY; MOUSE; NONHUMAN; PANCYTOPENIA; PRIORITY JOURNAL; PROTEIN FUNCTION;

ANIMALS; APOPTOSIS; CELL CYCLE; CELL PROLIFERATION; CELL SURVIVAL; ENERGY METABOLISM; FEMALE; GENE DELETION; HEMATOPOIESIS; HEMATOPOIETIC STEM CELLS; HOMEOSTASIS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; PANCYTOPENIA; PHENOTYPE; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; SURVIVAL ANALYSIS; TRANSCRIPTION FACTORS;

EUKARYOTA; MUS;

EID: 78649874959     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature09595     Document Type: Article

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